Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0153 | 0.4701 | 0.5672 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.1262 | 0.1332 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0795 | 0.1901 |
Schistosoma mansoni | ran | 0.0021 | 0.0318 | 0.0324 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0321 | 0.0663 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.0321 | 0.097 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0035 | 0.0795 | 0.2629 |
Brugia malayi | glutathione reductase | 0.0097 | 0.2827 | 0.5835 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.0321 | 0.097 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.0321 | 0.0328 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0318 | 0.0336 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.0321 | 0.097 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.0321 | 0.0339 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0795 | 0.2629 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0387 | 0.0319 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0795 | 0.073 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0321 | 0.0339 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0033 | 0.0744 | 0.2446 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0321 | 0.0339 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0795 | 0.073 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0321 | 0.0339 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0045 | 0.1134 | 0.1071 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.0321 | 0.0339 |
Giardia lamblia | Kinase, PLK | 0.0092 | 0.2657 | 0.2416 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0092 | 0.2657 | 0.5486 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0321 | 0.0339 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2657 | 0.2605 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0321 | 0.0339 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0744 | 0.2446 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0314 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0744 | 0.2446 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0321 | 0.0663 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.3909 | 0.4127 |
Brugia malayi | RNA binding protein | 0.0129 | 0.3909 | 0.8069 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0033 | 0.0744 | 0.17 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0321 | 0.0328 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.022 | 0.6909 | 0.8837 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0033 | 0.0744 | 0.17 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0795 | 0.2629 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3909 | 0.3988 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.0321 | 0.0339 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.0321 | 0.0328 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0321 | 0.0339 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.0321 | 0.0663 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0035 | 0.0795 | 0.0839 |
Plasmodium vivax | glutathione reductase, putative | 0.0097 | 0.2827 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0795 | 0.073 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0387 | 0.0319 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0013 | 0.007 | 0.0145 |
Plasmodium falciparum | glutathione reductase | 0.0097 | 0.2827 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.0321 | 0.0339 |
Schistosoma mansoni | alpha-glucosidase | 0.0136 | 0.4119 | 0.4203 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0321 | 0.0663 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0033 | 0.0744 | 0.5 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0318 | 0.0336 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0033 | 0.0744 | 0.2446 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.022 | 0.6909 | 0.8837 |
Trypanosoma brucei | trypanothione reductase | 0.0097 | 0.2827 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0097 | 0.2827 | 0.2984 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.0321 | 0.0663 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.022 | 0.6909 | 0.8837 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0318 | 0.0899 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0045 | 0.1134 | 0.1071 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0321 | 0.0339 |
Echinococcus multilocularis | snurportin 1 | 0.0298 | 0.9472 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0321 | 0.0339 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0321 | 0.0328 |
Plasmodium falciparum | glutathione reductase | 0.0033 | 0.0744 | 0.17 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0033 | 0.0744 | 0.2446 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.1262 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0321 | 0.0339 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0744 | 0.2446 |
Toxoplasma gondii | thioredoxin reductase | 0.0097 | 0.2827 | 1 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0561 | 0.1159 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0321 | 0.0339 |
Trypanosoma brucei | polo-like protein kinase | 0.0092 | 0.2657 | 0.9386 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.0321 | 0.0339 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0321 | 0.0663 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.0321 | 0.0339 |
Loa Loa (eye worm) | glutathione reductase | 0.0097 | 0.2827 | 0.2984 |
Schistosoma mansoni | kinase | 0.0047 | 0.1174 | 0.1197 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0033 | 0.0744 | 0.0786 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0795 | 0.073 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0318 | 0.0899 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 1 | 1 |
Schistosoma mansoni | ran | 0.0021 | 0.0318 | 0.0324 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0387 | 0.1149 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0321 | 0.0328 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0321 | 0.0339 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0321 | 0.0339 |
Onchocerca volvulus | 0.0021 | 0.0321 | 0.097 | |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.0321 | 0.0328 |
Mycobacterium tuberculosis | Probable reductase | 0.022 | 0.6909 | 0.8837 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0033 | 0.0744 | 0.1537 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0033 | 0.0744 | 0.0759 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0097 | 0.2827 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0795 | 0.073 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0321 | 0.0663 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0033 | 0.0744 | 0.0679 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0033 | 0.0744 | 0.0679 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.0321 | 0.0328 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.0321 | 0.0328 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0033 | 0.0744 | 0.2446 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0321 | 0.0663 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0035 | 0.0795 | 0.0839 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0033 | 0.0744 | 0.0786 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0033 | 0.0744 | 0.2446 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0153 | 0.4701 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0097 | 0.2827 | 0.5835 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.3909 | 0.4127 |
Plasmodium falciparum | thioredoxin reductase | 0.0097 | 0.2827 | 1 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0561 | 0.0592 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0097 | 0.2827 | 0.2985 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0033 | 0.0744 | 0.5 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0033 | 0.0744 | 0.2446 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.1262 | 0.1332 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0561 | 0.0969 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0321 | 0.0663 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0321 | 0.0663 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.0321 | 0.0339 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0387 | 0.0319 |
Leishmania major | trypanothione reductase | 0.0097 | 0.2827 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2657 | 0.2605 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0321 | 0.0339 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0245 | 0.772 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0097 | 0.2827 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2657 | 0.2605 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0318 | 0.0336 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0321 | 0.0663 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0561 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0321 | 0.0339 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0158 | 0.4844 | 0.5114 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0033 | 0.0744 | 0.2446 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0035 | 0.0795 | 0.1641 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0387 | 0.0319 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0033 | 0.0744 | 0.17 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.0321 | 0.0663 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.1262 | 0.1332 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3909 | 0.3988 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.0321 | 0.0328 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0321 | 0.0663 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0033 | 0.0744 | 0.2446 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.0321 | 0.0328 |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.3909 | 0.4127 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0321 | 0.0339 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0033 | 0.0744 | 0.2446 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0744 | 0.2446 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 1 | 1 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0387 | 0.1149 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0097 | 0.2827 | 0.2984 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0561 | 0.1781 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0035 | 0.0795 | 0.0839 |
Trypanosoma brucei | glucosidase, putative | 0.0035 | 0.0795 | 0.2629 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0035 | 0.0795 | 0.073 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.1262 | 0.1287 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.1262 | 0.1332 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0318 | 0.025 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0245 | 0.772 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0025 | 0.0451 | 0.0932 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0245 | 0.772 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2657 | 0.2605 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.2657 | 0.9386 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.0321 | 0.0339 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.2657 | 0.9386 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0795 | 0.073 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3909 | 0.3988 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.2657 | 0.2711 |
Onchocerca volvulus | 0.0091 | 0.265 | 0.9972 | |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0795 | 0.073 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0321 | 0.0339 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.0321 | 0.0339 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0321 | 0.0339 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0314 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.0321 | 0.0663 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.3909 | 0.4127 |
Plasmodium falciparum | thioredoxin reductase | 0.0033 | 0.0744 | 0.17 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0158 | 0.4844 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0744 | 0.2446 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0318 | 0.0899 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0561 | 0.1781 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0033 | 0.0744 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0136 | 0.4119 | 0.4203 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0033 | 0.0744 | 0.17 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0321 | 0.0663 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0561 | 0.0573 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0744 | 0.2446 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.1262 | 0.1287 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2657 | 0.2605 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0795 | 0.073 |
Onchocerca volvulus | 0.0015 | 0.015 | 0.0307 | |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0092 | 0.2657 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0321 | 0.0339 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0744 | 0.2446 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0795 | 0.073 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2657 | 0.2605 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0318 | 0.0657 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0321 | 0.0339 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0744 | 0.2446 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.022 | 0.6909 | 0.8837 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0321 | 0.0663 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.0321 | 0.0339 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0321 | 0.0339 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.0321 | 0.0328 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2657 | 0.2605 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0158 | 0.4844 | 0.5114 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0561 | 0.0969 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0033 | 0.0744 | 0.17 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.022 | 0.6909 | 0.8837 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.0321 | 0.0328 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0092 | 0.2657 | 0.2805 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0035 | 0.0795 | 0.073 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.007 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0561 | 0.0592 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0321 | 0.0663 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0318 | 0.025 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.022 | 0.6909 | 0.7313 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.3909 | 0.4127 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0092 | 0.2657 | 0.2605 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0033 | 0.0744 | 0.044 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0245 | 0.772 | 1 |
Echinococcus granulosus | snurportin 1 | 0.0298 | 0.9472 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0298 | 0.9472 | 0.9664 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 1 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0314 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0158 | 0.4844 | 0.5114 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.1262 | 0.2604 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0321 | 0.0339 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.1262 | 0.1332 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 1 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0033 | 0.0744 | 0.17 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0097 | 0.2827 | 0.2984 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3909 | 0.3988 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0321 | 0.0663 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0092 | 0.2657 | 0.9386 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.3909 | 0.8069 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0561 | 0.0592 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0025 | 0.0451 | 0.0932 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0321 | 0.0663 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0321 | 0.0328 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0321 | 0.0339 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0298 | 0.9472 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0321 | 0.0339 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0158 | 0.4844 | 0.5114 |
Schistosoma mansoni | alpha glucosidase | 0.0035 | 0.0795 | 0.0811 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0321 | 0.0339 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3909 | 0.3988 |
Brugia malayi | RNA, U transporter 1 | 0.0079 | 0.2259 | 0.4664 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0092 | 0.2657 | 0.2805 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0092 | 0.2657 | 0.2805 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0318 | 0.0899 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.0321 | 0.0663 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.3909 | 0.8069 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.