Detailed information for compound 1562720

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 419.985 | Formula: C24H34ClNO3
  • H donors: 1 H acceptors: 2 LogP: 5.48 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCN(CC(COc1ccccc1C(=O)CCc1ccccc1)O)CCC.Cl
  • InChi: 1S/C24H33NO3.ClH/c1-3-16-25(17-4-2)18-21(26)19-28-24-13-9-8-12-22(24)23(27)15-14-20-10-6-5-7-11-20;/h5-13,21,26H,3-4,14-19H2,1-2H3;1H
  • InChiKey: KOZGVKPOPLZDRS-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.0224 0.103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.012 0.0503
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0014
Schistosoma mansoni protein tyrosine phosphatase 0.0018 0.005 0.0034
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Entamoeba histolytica hypothetical protein 0.0036 0.0185 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0015 0.0029 0.0024
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0298 0.2071 0.5985
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Trichomonas vaginalis Heterochromatin protein, putative 0.0014 0.0023 0.0014
Brugia malayi hypothetical protein 0.0024 0.0095 0.0161
Brugia malayi TAR-binding protein 0.013 0.0864 0.173
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Echinococcus granulosus chromobox protein 2 0.0014 0.0023 0.0006
Leishmania major hypothetical protein, conserved 0.0035 0.0176 0.4759
Trichomonas vaginalis set domain proteins, putative 0.0287 0.1996 1
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0185 0.0168
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0018 0.005 0.0068
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0018 0.005 0.0034
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0487 0.344 1
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0093 0.0591 0.3667
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0096 0.019
Schistosoma mansoni tar DNA-binding protein 0.013 0.0864 0.0849
Brugia malayi Pre-SET motif family protein 0.0037 0.0193 0.036
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0344 0.0668
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0298 0.2071 0.596
Mycobacterium ulcerans hypothetical protein 0.0024 0.0096 0.019
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.005 0.0034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.012 0.0503
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0066 0.1168
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0109 0.0707 0.0691
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0018 0.005 0.0034
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.019 0.1292 0.3579
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0015 0.0029 0.0024
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.0863 0.5492
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0176 0.0159
Loa Loa (eye worm) hypothetical protein 0.0057 0.0336 0.0684
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0066 0.005
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0018 0.005 0.0637
Echinococcus granulosus geminin 0.0205 0.14 0.1385
Plasmodium falciparum glutathione reductase 0.0057 0.0336 0.55
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0014 0.0023 0.0006
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0018 0.005 0.0034
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Mycobacterium ulcerans lipase LipD 0.0035 0.0176 0.0425
Onchocerca volvulus 0.0024 0.0095 0.0367
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0066 0.0104
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.0968 0.2609
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.1983 0.197
Onchocerca volvulus 0.0018 0.005 0.0138
Echinococcus multilocularis hypothetical protein 0.0018 0.005 0.0034
Brugia malayi Protein cec-1. 0.0014 0.0023 0.0013
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0018 0.005 0.0102
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0023 0.0006
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.005 0.0034
Brugia malayi glutathione reductase 0.0057 0.0336 0.0651
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0176 0.0425
Schistosoma mansoni hypothetical protein 0.0058 0.0344 0.0328
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0487 0.344 1
Plasmodium falciparum glutathione reductase 0.002 0.0066 0.0764
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0109 0.0707 0.0691
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0024 0.0099 0.0168
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0096 0.0339
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0176 0.0358
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.035 0.0712
Loa Loa (eye worm) histone methyltransferase 0.002 0.0065 0.0133
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0176 0.0159
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0096 0.2125
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0286 0.1333
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0039 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0176 0.0787
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0047
Echinococcus granulosus Chromobox protein 3 0.0014 0.0023 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Onchocerca volvulus 0.0018 0.005 0.0138
Onchocerca volvulus 0.0018 0.005 0.0138
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.0224 0.103
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0039 0.0022
Echinococcus granulosus tar DNA binding protein 0.013 0.0864 0.0849
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0018 0.005 0.0034
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.1535 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0142 0.0951 0.0936
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Loa Loa (eye worm) hypothetical protein 0.0041 0.0221 0.0449
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0061 0.009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0193 0.0177
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0018 0.005 0.0034
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.0863 0.5492
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0487 0.344 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0052 0.0512
Echinococcus granulosus GPCR family 2 0.0019 0.0061 0.0044
Echinococcus granulosus RUN 0.0024 0.0095 0.0079
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0336 0.0319
Brugia malayi Cytochrome P450 family protein 0.0015 0.0031 0.0029
Echinococcus granulosus dnaJ subfamily B 0.0842 0.5997 0.5991
Loa Loa (eye worm) hypothetical protein 0.0035 0.0176 0.0358
Mycobacterium leprae Probable lipase LipE 0.0035 0.0176 0.024
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0061 0.0044
Loa Loa (eye worm) TAR-binding protein 0.013 0.0864 0.1758
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0064 0.0095
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0018 0.005 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0193 0.0177
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0176 0.0787
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0018 0.005 0.0034
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0176 0.0787
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0095 0.0079
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0286 0.027
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Onchocerca volvulus 0.0018 0.005 0.0138
Schistosoma mansoni cpg binding protein 0.0062 0.0374 0.0358
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0075 0.0276
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0096 0.2125
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0061 0.0044
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0193 0.0177
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0066 0.1168
Brugia malayi hypothetical protein 0.0122 0.0806 0.1611
Toxoplasma gondii thioredoxin reductase 0.0057 0.0336 0.0915
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0066 0.0127
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Onchocerca volvulus 0.0122 0.0806 0.3967
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0061 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0106
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.012 0.0503
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0068 0.024
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.0274 0.0258
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0018 0.005 0.0102
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.0274 0.0258
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0018 0.005 0.1686
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0176 0.4759
Schistosoma mansoni chromobox protein 0.0014 0.0023 0.0006
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0047 0.0096
Echinococcus multilocularis Chromo domain 0.0014 0.0023 0.0006
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0692 0.4916 0.4907
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Schistosoma mansoni cpg binding protein 0.0059 0.035 0.0334
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0045 0.0245 0.0498
Onchocerca volvulus 0.005 0.0286 0.1333
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0106
Schistosoma mansoni hypothetical protein 0.0024 0.0095 0.0079
Brugia malayi Thioredoxin reductase 0.0057 0.0336 0.0651
Brugia malayi M-phase phosphoprotein, mpp8 0.0122 0.0806 0.1611
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0066 0.1168
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0095 0.0079
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0176 0.0787
Loa Loa (eye worm) hypothetical protein 0.006 0.0358 0.0728
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0023 0.0014
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0039 0.0022
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0174 0.0158
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0198 0.1352 0.1337
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0066 0.1168
Brugia malayi hypothetical protein 0.0018 0.005 0.0068
Onchocerca volvulus 0.0018 0.005 0.0138
Schistosoma mansoni hypothetical protein 0.0205 0.14 0.1385
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0066 0.0764
Onchocerca volvulus 0.0035 0.0176 0.0774
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0096 0.019
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0045 0.0245 0.0229
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0066 0.1168
Onchocerca volvulus 0.0018 0.005 0.0138
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0024 0.0099 0.0201
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0106
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0096 0.0161
Echinococcus multilocularis 0.0018 0.005 0.0034
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.0968 0.6196
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0066 0.1168
Echinococcus granulosus Chromo domain 0.0014 0.0023 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Brugia malayi beta-lactamase family protein 0.0035 0.0176 0.0325
Trypanosoma brucei trypanothione reductase 0.0057 0.0336 1
Brugia malayi hypothetical protein 0.0018 0.005 0.0068
Schistosoma mansoni hypothetical protein 0.0019 0.0061 0.0044
Entamoeba histolytica hypothetical protein 0.0036 0.0185 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0052 0.0047
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0018 0.005 0.0034
Loa Loa (eye worm) heterochromatin protein 1 0.0014 0.0023 0.0047
Brugia malayi hypothetical protein 0.0036 0.0185 0.0342
Onchocerca volvulus 0.0018 0.005 0.0138
Schistosoma mansoni chromobox protein 0.0014 0.0023 0.0006
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0018 0.005 0.0034
Brugia malayi hypothetical protein 0.0018 0.005 0.0068
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0018 0.005 0.0034
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0176 0.0878
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0095 0.0079
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0093 0.0591 0.1173
Onchocerca volvulus 0.0018 0.005 0.0138
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0096 0.019
Plasmodium falciparum thioredoxin reductase 0.0057 0.0336 0.55
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0253 0.1746 0.3551
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0066 0.0143
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.1983 0.197
Schistosoma mansoni hypothetical protein 0.0019 0.0061 0.0044
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0031 0.0063
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0336 0.0652
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.005 0.0034
Onchocerca volvulus 0.0018 0.005 0.0138
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0066 0.0233
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0075 0.0276
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0018 0.005 0.0034
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0018 0.005 0.0637
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0061 0.0124
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0047 0.0031
Brugia malayi SET domain containing protein 0.0016 0.0042 0.0051
Schistosoma mansoni tar DNA-binding protein 0.013 0.0864 0.0849
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0014
Loa Loa (eye worm) hypothetical protein 0.0035 0.0176 0.0358
Brugia malayi RNA recognition motif domain containing protein 0.013 0.0864 0.173
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0018 0.005 0.1686
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0066 0.1168
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0066 0.0104
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0095 0.1274
Brugia malayi Protein-tyrosine phosphatase 1 0.0018 0.005 0.0068
Onchocerca volvulus 0.0018 0.005 0.0138
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0018 0.005 0.1686
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0286 0.027
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0018 0.005 0.0034
Onchocerca volvulus 0.0018 0.005 0.0138
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0176 0.0425
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Loa Loa (eye worm) protein tyrosine phosphatase 0.0018 0.005 0.0102
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0018 0.005 0.0637
Schistosoma mansoni protein tyrosine phosphatase 0.0018 0.005 0.0034
Entamoeba histolytica hypothetical protein 0.0036 0.0185 1
Schistosoma mansoni hypothetical protein 0.0041 0.0221 0.0204
Onchocerca volvulus 0.0018 0.005 0.0138
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0096 0.019
Onchocerca volvulus 0.0024 0.0096 0.0368
Mycobacterium ulcerans hypothetical protein 0.0024 0.0099 0.0201
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0096 0.019
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.0968 0.6196
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0052 0.0512
Onchocerca volvulus 0.0051 0.0292 0.1365
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0176 0.4759
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.0863 0.5492
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0066 0.1168
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0014
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0093 0.0591 1
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0298 0.2071 1
Schistosoma mansoni tar DNA-binding protein 0.013 0.0864 0.0849
Loa Loa (eye worm) hypothetical protein 0.0286 0.1983 0.4035
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0023 0.0014
Schistosoma mansoni hypothetical protein 0.0019 0.0061 0.0044
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0039 0.0022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0066 0.1168
Echinococcus multilocularis Chromobox protein 3 0.0014 0.0023 0.0006
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0193 0.0177
Loa Loa (eye worm) glutathione reductase 0.0057 0.0336 0.0683
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0193 0.0498
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0018 0.005 0.0034
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0692 0.4916 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0336 0.032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.012 0.0503
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0061 0.009
Loa Loa (eye worm) hypothetical protein 0.0037 0.0193 0.0393
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Trichomonas vaginalis hypothetical protein 0.0014 0.0023 0.0014
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0066 0.005
Onchocerca volvulus 4.1 G protein, putative homolog 0.0018 0.005 0.0138
Schistosoma mansoni hypothetical protein 0.0014 0.0023 0.0006
Onchocerca volvulus 0.0018 0.005 0.0138
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0066 0.0233
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0336 0.195
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Schistosoma mansoni pcd6 interacting protein-related 0.0018 0.005 0.0034
Schistosoma mansoni lipoxygenase 0.0142 0.0951 0.0936
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0109 0.0707 0.0691
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0093 0.0591 0.1482
Echinococcus multilocularis tar DNA binding protein 0.013 0.0864 0.0849
Echinococcus multilocularis chromobox protein 2 0.0014 0.0023 0.0006
Loa Loa (eye worm) hypothetical protein 0.0093 0.0591 0.1203
Onchocerca volvulus 0.0058 0.0344 0.1626
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0185 0.0168
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0034
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0066 0.0127
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0018 0.005 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0096 0.0194
Loa Loa (eye worm) beta-lactamase 0.0035 0.0176 0.0358
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0018 0.005 0.0034
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.019 0.1292 0.8373
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0096 0.0161
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0066 0.0764
Brugia malayi hypothetical protein 0.0018 0.005 0.0068
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0066 0.1168
Brugia malayi CXXC zinc finger family protein 0.0059 0.035 0.068
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0106
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Echinococcus multilocularis dnaJ subfamily B 0.0842 0.5997 0.5991
Leishmania major tyrosine specific protein phosphatase, putative 0.0018 0.005 0.0637
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0018 0.005 0.0034
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Mycobacterium ulcerans epimerase 0.0024 0.0099 0.0201
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0066 0.1168
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0047 0.0031
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Echinococcus multilocularis geminin 0.0205 0.14 0.1385
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0176 0.0159
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0176 0.0878
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0336 0.032
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0018 0.005 0.0034
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0286 0.027
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0047 0.0031
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Loa Loa (eye worm) hypothetical protein 0.0122 0.0806 0.1639
Schistosoma mansoni loxhd1 0.0024 0.0095 0.0079
Echinococcus multilocularis GPCR, family 2 0.0019 0.0061 0.0044
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0109 0.0707 0.0691
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0018 0.005 0.0034
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0692 0.4916 0.4907
Schistosoma mansoni chromobox protein 0.0014 0.0023 0.0006
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0336 0.0683
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0096 0.019
Brugia malayi Protein-tyrosine phosphatase 0.0018 0.005 0.0068
Plasmodium vivax SET domain protein, putative 0.0037 0.0193 0.2992
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0336 0.55
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Onchocerca volvulus 0.0035 0.0176 0.0774
Mycobacterium ulcerans beta-lactamase 0.0035 0.0176 0.0425
Schistosoma mansoni hypothetical protein 0.0019 0.0061 0.0044
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0096 0.4493
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0193 0.0177
Loa Loa (eye worm) hypothetical protein 0.0039 0.0203 0.0412
Brugia malayi hypothetical protein 0.0286 0.1983 0.4014
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0176 0.0878
Brugia malayi Associated with TFs and helicases family protein 0.0014 0.0023 0.0013
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Schistosoma mansoni cpg binding protein 0.0062 0.0374 0.0358
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.0863 0.5492
Echinococcus multilocularis chromobox protein 1 0.0014 0.0023 0.0006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0096 0.4493
Loa Loa (eye worm) hypothetical protein 0.0035 0.0176 0.0358
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0099 0.0011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0066 0.1168
Mycobacterium ulcerans endonuclease IV 0.0093 0.0591 0.1644
Onchocerca volvulus 0.0018 0.005 0.0138
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0286 0.0582
Brugia malayi chromobox protein homolog 3 0.0014 0.0023 0.0013
Mycobacterium tuberculosis Conserved protein 0.0035 0.0176 0.0878
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Schistosoma mansoni tar DNA-binding protein 0.013 0.0864 0.0849
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.012 0.0503
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.005 0.0034
Leishmania major trypanothione reductase 0.0057 0.0336 1
Toxoplasma gondii ABC1 family protein 0.0035 0.0176 0.0447
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0096 0.4493
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0065 0.0048
Brugia malayi beta-lactamase 0.0035 0.0176 0.0325
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0018 0.005 0.0068
Chlamydia trachomatis endonuclease IV 0.0093 0.0591 0.1592
Brugia malayi Valyl-tRNA synthetase 0.0014 0.0023 0.0013
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.0968 0.6196
Schistosoma mansoni chromobox protein 0.0014 0.0023 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0176 0.2689
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0023 0.0014
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0741 0.2102
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Onchocerca volvulus 0.0018 0.005 0.0138
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0018 0.005 0.0034
Onchocerca volvulus 0.0018 0.005 0.0138
Echinococcus multilocularis microtubule associated protein 2 0.1397 1 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0095 0.0079
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0176 0.0787
Brugia malayi hypothetical protein 0.0024 0.0095 0.0161
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0014 0.0023 0.0006
Loa Loa (eye worm) MBCTL1 0.0057 0.0336 0.0684
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Onchocerca volvulus 0.0035 0.0176 0.0774
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0286 0.027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0047
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0052 0.0063
Loa Loa (eye worm) hypothetical protein 0.0247 0.1709 0.3476
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0018 0.005 0.0034
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0061 0.0044
Chlamydia trachomatis dehyroquinate synthase 0.019 0.1292 0.3661
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0045 0.0245 0.0466
Onchocerca volvulus 0.0018 0.005 0.0138
Trichomonas vaginalis esterase, putative 0.0035 0.0176 0.0787
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0358 0.0728
Onchocerca volvulus 0.0122 0.0806 0.3967
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0023 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.012 0.0503
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Echinococcus multilocularis chromobox protein 1 0.0014 0.0023 0.0006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.012 0.0503
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0018 0.005 0.0034
Mycobacterium tuberculosis Probable reductase 0.013 0.0863 0.5492
Schistosoma mansoni hypothetical protein 0.0205 0.14 0.1385
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0066 0.1168
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0176 0.4759
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0096 0.019
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Brugia malayi Protein-tyrosine phosphatase 0.0018 0.005 0.0068
Brugia malayi Heterochromatin protein 1 0.0014 0.0023 0.0013
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0095 0.0079
Echinococcus multilocularis cpg binding protein 0.0062 0.0374 0.0358
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0014 0.0023 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0023 0.0014
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0692 0.4916 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0014
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0066 0.1168
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0096 0.0161
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0358 0.0696
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0095 0.0194
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0286 0.027
Trypanosoma brucei protein tyrosine phosphatase 1 0.0018 0.005 0.0637
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0031 0.0063
Echinococcus granulosus chromobox protein 1 0.0014 0.0023 0.0006
Brugia malayi Doublecortin family protein 0.0024 0.0095 0.0161
Brugia malayi Cytochrome P450 family protein 0.0015 0.0031 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0014
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0018 0.005 0.0034
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0018 0.005 0.0034
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0336 0.032
Mycobacterium ulcerans 3-dehydroquinate synthase 0.019 0.1292 0.3701
Mycobacterium tuberculosis Conserved protein 0.0035 0.0176 0.0878
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0286 0.027
Brugia malayi mbt repeat family protein 0.005 0.0286 0.055
Schistosoma mansoni polycystin 1-related 0.0024 0.0095 0.0079
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0023 0.0014
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Schistosoma mansoni hypothetical protein 0.0036 0.0185 0.0168
Schistosoma mansoni survival motor neuron protein 0.0058 0.0344 0.0328
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0018 0.005 0.0034
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0176 0.024
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0487 0.344 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0018 0.005 0.0034
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.005 0.0102
Brugia malayi photoreceptor-specific nuclear receptor 0.0247 0.1709 0.3453
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0047
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0142 0.0951 0.0936
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0047
Schistosoma mansoni protein tyrosine phosphatase 0.0018 0.005 0.0034
Brugia malayi beta-lactamase family protein 0.0035 0.0176 0.0325
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0018 0.005 0.0034
Loa Loa (eye worm) hypothetical protein 0.005 0.0286 0.0582
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0018 0.005 0.0102
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0095 0.0079
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0047
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0018 0.005 0.0034
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0018 0.005 0.0034
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0023 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Echinococcus granulosus cpg binding protein 0.0062 0.0374 0.0358
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0096 0.2125
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0176 0.0878
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.0863 0.5492
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0095 0.1274
Onchocerca volvulus 0.0287 0.1996 1
Toxoplasma gondii endonuclease IV APN 0.0093 0.0591 0.1663
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0023 0.0006
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.002 0.0066 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Loa Loa (eye worm) hypothetical protein 0.0122 0.0806 0.1639
Loa Loa (eye worm) hypothetical protein 0.0024 0.0096 0.0194
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0221 0.0416
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Entamoeba histolytica hypothetical protein 0.0036 0.0185 1
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0093 0.0591 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0176 0.0878
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0014
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0198 0.1352 0.1337
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Loa Loa (eye worm) hypothetical protein 0.0035 0.0176 0.0358
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Mycobacterium tuberculosis Conserved hypothetical protein 0.0024 0.0099 0.0363
Mycobacterium ulcerans hypothetical protein 0.0035 0.0176 0.0425
Brugia malayi mbt repeat family protein 0.005 0.0286 0.055
Loa Loa (eye worm) hypothetical protein 0.0024 0.0099 0.0202
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0193 0.0177
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0124
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0692 0.4916 0.4907
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0047
Plasmodium vivax glutathione reductase, putative 0.0057 0.0336 0.55
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0066 0.1168
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0336 0.032
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0298 0.2071 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0065 0.0048
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0185 0.0168
Loa Loa (eye worm) hypothetical protein 0.0024 0.0095 0.0194
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0176 0.0878
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0023 0.0014
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0066 0.0764
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0066 0.1168
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0176 0.0159
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0023 0.0014
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0031 0.0063
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0286 0.027
Onchocerca volvulus 0.0018 0.005 0.0138
Schistosoma mansoni tar DNA-binding protein 0.013 0.0864 0.0849
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0018 0.005 0.0034
Onchocerca volvulus 0.0018 0.005 0.0138
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.019 0.1292 0.8373
Loa Loa (eye worm) hypothetical protein 0.0024 0.0095 0.0194
Plasmodium falciparum thioredoxin reductase 0.002 0.0066 0.0764
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0066 0.0104
Echinococcus granulosus chromobox protein 1 0.0014 0.0023 0.0006
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0066 0.0764
Onchocerca volvulus 0.0018 0.005 0.0138
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0024 0.0099 0.0386
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0176 0.0878
Loa Loa (eye worm) RNA binding protein 0.013 0.0864 0.1758
Brugia malayi Pre-SET motif family protein 0.0253 0.1746 0.3529
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.0863 0.2295
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0106
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0066 0.005
Loa Loa (eye worm) hypothetical protein 0.0035 0.0176 0.0358
Trichomonas vaginalis pten, drome, putative 0.0018 0.005 0.0152
Onchocerca volvulus 0.0018 0.005 0.0138
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.012 0.0503
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0358 0.0696
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0176 0.0878
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0066 1
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0336 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0096 0.0339
Loa Loa (eye worm) hypothetical protein 0.0035 0.0176 0.0358
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0336 0.032
Echinococcus multilocularis RUN 0.0024 0.0095 0.0079
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0018 0.005 0.0034
Schistosoma mansoni hypothetical protein 0.0842 0.5997 0.5991
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0018 0.005 0.0102
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0018 0.005 0.0034
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0838 0.0822
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0336 0.0319
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0039 0.0022
Loa Loa (eye worm) helicase 0.0014 0.0023 0.0047
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0018 0.005 0.0034
Schistosoma mansoni rab6-interacting 0.0024 0.0095 0.0079
Loa Loa (eye worm) hypothetical protein 0.0024 0.0096 0.0194
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Onchocerca volvulus 0.0059 0.035 0.1658
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0023 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0051 0.0292 0.0276
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.013 0.0864 0.1758
Onchocerca volvulus 0.0018 0.005 0.0138
Onchocerca volvulus 0.0024 0.0095 0.0367
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0045 0.0245 0.0229
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0066 0.0101
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Brugia malayi RNA binding protein 0.013 0.0864 0.173
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0176 0.0325
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0066 0.1168
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0023 0.0014
Brugia malayi hypothetical protein 0.0018 0.005 0.0068
Echinococcus granulosus protein tyrosine phosphatase n9 0.0018 0.005 0.0034
Schistosoma mansoni 3-dehydroquinate synthase 0.019 0.1292 0.1278
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0023 0.0006
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.005 0.0034
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.005 0.0068
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.005 0.0034
Schistosoma mansoni lipoxygenase 0.01 0.0642 0.0626
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0102
Schistosoma mansoni microtubule-associated protein tau 0.1397 1 1
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0018 0.005 0.0034
Brugia malayi CHD4 protein 0.0017 0.0047 0.0062
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0018 0.005 0.0637
Schistosoma mansoni rab6-interacting 0.0024 0.0095 0.0079
Onchocerca volvulus 0.0018 0.005 0.0138
Schistosoma mansoni hypothetical protein 0.0305 0.2127 0.2114

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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