Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.025 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0155 | 0.4444 | 0.396 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0155 | 0.4444 | 0.396 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.025 | 1 | 1 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.025 | 1 | 1 |
Treponema pallidum | adenosine deaminase | 0.0092 | 0.0802 | 0.5 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0155 | 0.4444 | 0.396 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.025 | 1 | 1 |
Plasmodium falciparum | adenosylhomocysteinase | 0.025 | 1 | 1 |
Echinococcus granulosus | adenosylhomocysteinase | 0.025 | 1 | 1 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.025 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.025 | 1 | 1 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.025 | 1 | 1 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.025 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0155 | 0.4444 | 0.396 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.025 | 1 | 1 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.025 | 1 | 0.5 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.025 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0092 | 0.0802 | 0.0802 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0092 | 0.0802 | 0.5 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.025 | 1 | 0.5 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.025 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.025 | 1 | 1 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.025 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0092 | 0.0802 | 0.0802 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.025 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.