Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0646 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0203 | 0.2452 | 0.2068 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0646 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0646 | 1 | 1 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0646 | 1 | 1 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0646 | 1 | 0.5 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0087 | 0.0484 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0087 | 0.0484 | 0.5 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0646 | 1 | 0.5 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0646 | 1 | 0.5 |
Schistosoma mansoni | adenosylhomocysteinase | 0.04 | 0.5807 | 0.5593 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0646 | 1 | 1 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0646 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0646 | 1 | 1 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0646 | 1 | 1 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0646 | 1 | 1 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0646 | 1 | 1 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0646 | 1 | 1 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0646 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.04 | 0.5807 | 0.5593 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0646 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0484 | 0.0484 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0646 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.04 | 0.5807 | 0.5593 |
Schistosoma mansoni | adenosylhomocysteinase | 0.04 | 0.5807 | 0.5593 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0646 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.