Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1331 | 0.1849 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0133 | 0.0083 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.1245 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1077 | 0.0961 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.2757 | 0.3903 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0037 | 0.0789 | 0.0718 |
Brugia malayi | Protein kinase domain containing protein | 0.0015 | 0.0129 | 0.000000094103 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.1543 | 0.1433 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0561 | 0.0715 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.1245 | 0.8071 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0429 | 0.0543 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0388 | 0.0314 |
Onchocerca volvulus | Netrin receptor homolog | 0.0015 | 0.0129 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.467 | 0.6771 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.005 | 0.1175 | 0.1059 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.066 | 0.0589 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0709 | 0.0953 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.1543 | 0.1478 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0431 | 0.0545 |
Schistosoma mansoni | lamin | 0.0055 | 0.1331 | 0.1218 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0037 | 0.0782 | 0.5068 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.1543 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0243 | 0.6893 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.015 | 0.0135 |
Brugia malayi | hypothetical protein | 0.0168 | 0.467 | 0.6745 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0155 | 0.4285 | 0.6202 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.1245 | 1 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.075 | 0.6026 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.3001 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.1077 | 0.1476 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0015 | 0.0133 | 0.0004 |
Brugia malayi | Pre-SET motif family protein | 0.0213 | 0.6021 | 0.8751 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1077 | 0.0961 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.2757 | 0.3903 |
Echinococcus multilocularis | geminin | 0.0347 | 1 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.015 | 0.1204 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.1543 | 0.1478 |
Brugia malayi | hypothetical protein | 0.0111 | 0.3001 | 0.4266 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0076 | 0.0026 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0015 | 0.015 | 0.0972 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0076 | 0.1937 | 0.1876 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.3001 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.066 | 0.0589 |
Loa Loa (eye worm) | ICD-1 protein | 0.0036 | 0.075 | 0.0994 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0015 | 0.0129 | 0.0053 |
Brugia malayi | hypothetical protein | 0.0052 | 0.1245 | 0.1658 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0076 | 0.0026 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0046 | 0.1061 | 0.0945 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0694 | 0.084 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0482 | 0.0598 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.1077 | 0.1009 |
Schistosoma mansoni | hypothetical protein | 0.0111 | 0.3001 | 0.291 |
Echinococcus granulosus | transcription factor btf3 | 0.0036 | 0.075 | 0.068 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0611 | 0.0539 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.015 | 0.1204 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.1245 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0781 | 0.1058 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0562 | 0.049 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.051 | 0.0661 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0241 | 0.6862 | 0.6838 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.015 | 0.0135 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0241 | 0.6862 | 0.6838 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.1153 | 0.1521 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0046 | 0.1061 | 0.1624 |
Leishmania major | protein kinase, putative | 0.0013 | 0.0076 | 0.0492 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0213 | 0.6021 | 0.8761 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0034 | 0.0709 | 0.0862 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0076 | 0.0026 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0614 | 0.0543 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0046 | 0.1061 | 0.6879 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.1153 | 0.1037 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0781 | 0.1058 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.1571 | 0.1461 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.071 | 0.0954 |
Brugia malayi | beta-NAC-like protein | 0.0036 | 0.075 | 0.0923 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0076 | 0.1937 | 0.1876 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.071 | 0.0954 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.003 | 0.0569 | 0.0727 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.075 | 0.0281 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.066 | 0.0589 |
Brugia malayi | Cytochrome P450 family protein | 0.0046 | 0.1071 | 0.1399 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.1077 | 0.1009 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.1245 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0611 | 0.0488 |
Schistosoma mansoni | hypothetical protein | 0.0347 | 1 | 1 |
Leishmania major | basic transcription factor 3a, putative | 0.0036 | 0.075 | 0.4863 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0429 | 0.0543 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.1543 | 0.1433 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.066 | 0.0589 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0611 | 0.0539 |
Brugia malayi | PAS domain containing protein | 0.005 | 0.1175 | 0.1553 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0614 | 0.0721 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.1153 | 0.1037 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1543 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0076 | 0.0026 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0046 | 0.1061 | 0.8524 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.066 | 0.0861 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.3001 | 1 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0015 | 0.015 | 0.1204 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.3001 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0076 | 0.0026 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.1077 | 0.1009 |
Echinococcus multilocularis | expressed protein | 0.0034 | 0.0709 | 0.0638 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0781 | 0.1058 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.1077 | 0.1009 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0046 | 0.1061 | 0.1452 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0046 | 0.1071 | 0.1466 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0046 | 0.1061 | 0.8524 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1543 | 1 |
Echinococcus granulosus | expressed protein | 0.0034 | 0.0709 | 0.0638 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0561 | 0.0438 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0431 | 0.0545 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.066 | 0.0538 |
Echinococcus granulosus | lamin | 0.0055 | 0.1331 | 0.1265 |
Brugia malayi | hypothetical protein | 0.0241 | 0.6862 | 1 |
Schistosoma mansoni | transcription factor btf3 | 0.0036 | 0.075 | 0.063 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0015 | 0.015 | 0.0109 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.066 | 0.0589 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0046 | 0.1061 | 0.8524 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0034 | 0.0685 | 0.4442 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0034 | 0.0685 | 0.5503 |
Echinococcus granulosus | Ankyrin | 0.0015 | 0.0133 | 0.0057 |
Schistosoma mansoni | intermediate filament proteins | 0.0055 | 0.1331 | 0.1218 |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.0709 | 0.0953 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0015 | 0.015 | 0.0075 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.1077 | 0.1409 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.1245 | 0.8071 |
Onchocerca volvulus | 0.0031 | 0.0614 | 0.079 | |
Onchocerca volvulus | 0.0049 | 0.1153 | 0.1579 | |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0614 | 0.3982 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0111 | 0.3001 | 0.2947 |
Schistosoma mansoni | lamin | 0.0055 | 0.1331 | 0.1218 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.2757 | 0.395 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.071 | 0.0954 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0015 | 0.015 | 0.0031 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.066 | 0.0589 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.0685 | 0.5503 |
Brugia malayi | Uncoordinated protein 44 | 0.0015 | 0.0129 | 0.000000094103 |
Toxoplasma gondii | NAC domain-containing protein | 0.0036 | 0.075 | 0.4863 |
Giardia lamblia | GTOR | 0.0046 | 0.1061 | 0.5 |
Schistosoma mansoni | rotamase | 0.0034 | 0.0709 | 0.0588 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.058 | 0.0764 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.066 | 0.0538 |
Echinococcus multilocularis | musashi | 0.0055 | 0.1331 | 0.1265 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0076 | 0.0492 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.015 | 0.0135 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Echinococcus granulosus | lamin dm0 | 0.0055 | 0.1331 | 0.1265 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.066 | 0.0861 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1543 | 1 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Loa Loa (eye worm) | intermediate filament protein | 0.0055 | 0.1331 | 0.1849 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0037 | 0.0782 | 0.6279 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.075 | 0.6026 |
Brugia malayi | Death domain containing protein | 0.0015 | 0.0129 | 0.000000094103 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0015 | 0.0129 | 0.0053 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.071 | 0.0954 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0055 | 0.1331 | 0.1849 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1786 | 0.2521 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.071 | 0.0954 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.0685 | 0.5503 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0076 | 0.0026 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0034 | 0.071 | 0.4602 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0037 | 0.0782 | 0.6279 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1301 | 0.1805 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0013 | 0.0076 | 0.0026 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0111 | 0.3001 | 0.291 |
Wolbachia endosymbiont of Brugia malayi | parvulin-like peptidyl-prolyl isomerase, PPID | 0.001 | 0 | 0.5 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0036 | 0.075 | 0.0281 |
Brugia malayi | bHLH-PAS transcription factor | 0.0037 | 0.0789 | 0.098 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0027 | 0.0482 | 0.0409 |
Leishmania major | protein kinase, putative | 0.0013 | 0.0076 | 0.0492 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0388 | 0.0262 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0501 | 0.0649 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.066 | 0.0538 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0027 | 0.0482 | 0.0409 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0431 | 0.0545 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0611 | 0.0488 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0039 | 0.0861 | 0.1175 |
Echinococcus multilocularis | transcription factor btf3 | 0.0036 | 0.075 | 0.068 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0561 | 0.0642 |
Mycobacterium leprae | Possible regulatory protein | 0.0013 | 0.0076 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0046 | 0.1061 | 0.1468 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0076 | 0.0026 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.015 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.6862 | 1 |
Onchocerca volvulus | 0.0243 | 0.6897 | 1 | |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0614 | 0.0492 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0034 | 0.0685 | 0.4442 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0431 | 0.0545 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0015 | 0.0129 | 0.0053 |
Brugia malayi | intermediate filament protein | 0.0055 | 0.1331 | 0.1785 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.1245 | 1 |
Echinococcus multilocularis | Ankyrin | 0.0015 | 0.0133 | 0.0057 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0013 | 0.0076 | 0.0026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.015 | 0.0135 |
Schistosoma mansoni | hypothetical protein | 0.0106 | 0.2837 | 0.2743 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.051 | 0.0661 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0046 | 0.1061 | 0.1624 |
Echinococcus multilocularis | lamin dm0 | 0.0055 | 0.1331 | 0.1265 |
Onchocerca volvulus | 0.0055 | 0.1331 | 0.184 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1077 | 0.0961 |
Onchocerca volvulus | 0.0029 | 0.0561 | 0.0711 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.075 | 0.1013 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.075 | 0.1013 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0781 | 0.1058 |
Echinococcus granulosus | intermediate filament protein | 0.0055 | 0.1331 | 0.1265 |
Brugia malayi | hypoxia-induced factor 1 | 0.0155 | 0.4285 | 0.6172 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.003 | 0.0569 | 0.0654 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0015 | 0.0129 | 0.000000064185 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0452 | 0.0554 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.015 | 0.0135 |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.0685 | 0.0918 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0015 | 0.0129 | 0.0053 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.1786 | 0.2462 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.066 | 0.0789 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0055 | 0.1331 | 0.1785 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0013 | 0.0076 | 0.0026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.071 | 0.0954 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0111 | 0.3001 | 0.2947 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0019 | 0.026 | 0.2085 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0013 | 0.0076 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0452 | 0.0554 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0614 | 0.0492 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0046 | 0.1061 | 0.1468 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0046 | 0.1061 | 0.1385 |
Onchocerca volvulus | 0.0055 | 0.1331 | 0.184 | |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0015 | 0.015 | 0.0075 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0614 | 0.0543 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0076 | 0.0026 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.075 | 0.1013 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.2757 | 0.395 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0015 | 0.015 | 0.0021 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.1543 | 0.5 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0046 | 0.1061 | 0.8524 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.1245 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.061 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1245 | 0.1723 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0129 | 0.0078 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.1374 | 0.8901 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0036 | 0.075 | 0.6026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.071 | 0.0954 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.1543 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0614 | 0.0794 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0036 | 0.075 | 0.2156 |
Schistosoma mansoni | single-minded | 0.005 | 0.1175 | 0.1059 |
Schistosoma mansoni | hypothetical protein | 0.0347 | 1 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0388 | 0.0314 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.0709 | 0.0934 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0046 | 0.1061 | 0.6879 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0781 | 0.1058 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0015 | 0.0129 | 0.0078 |
Echinococcus granulosus | death domain containing protein | 0.0015 | 0.0129 | 0.0053 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0046 | 0.1061 | 0.1468 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0614 | 0.0543 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0501 | 0.0649 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0614 | 0.0492 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.066 | 0.0538 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0614 | 0.0492 |
Onchocerca volvulus | 0.0037 | 0.0789 | 0.1045 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.066 | 0.0789 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0022 | 0.0339 | 0.2719 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0429 | 0.0543 |
Echinococcus granulosus | single minded 2 | 0.0037 | 0.0789 | 0.0718 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0046 | 0.1061 | 0.0993 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.1786 | 0.1679 |
Echinococcus multilocularis | lamin | 0.0055 | 0.1331 | 0.1265 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.051 | 0.0661 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.015 | 0.1204 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0046 | 0.1061 | 0.0993 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 55 % | Inhibition of human recombinant MAGL assessed as remaining activity at 100 uM after 10 mins by spectrophotometry relative to control | ChEMBL. | 21982493 |
Activity (binding) | = 80 % | Inhibition of human recombinant MAGL assessed as remaining activity at 10 uM after 10 mins by spectrophotometry relative to control | ChEMBL. | 21982493 |
Activity (binding) | = 96 % | Inhibition of human recombinant MAGL assessed as remaining activity at 1 uM after 10 mins by spectrophotometry relative to control | ChEMBL. | 21982493 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.