Detailed information for compound 1565847

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 599.034 | Formula: C17H11Br3N8O2
  • H donors: 1 H acceptors: 8 LogP: 3.5 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(=O)Cn1nnc(n1)c1cncc(c1)c1nnn(c1)Cc1cc(Br)c(c(c1)Br)Br
  • InChi: 1S/C17H11Br3N8O2/c18-12-1-9(2-13(19)16(12)20)6-27-7-14(22-25-27)10-3-11(5-21-4-10)17-23-26-28(24-17)8-15(29)30/h1-5,7H,6,8H2,(H,29,30)
  • InChiKey: KFLRCBGJPSBTOG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Acyl-CoA desaturase 1 Starlite/ChEMBL References
Homo sapiens stearoyl-CoA desaturase (delta-9-desaturase) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) acyl-CoA desaturase Get druggable targets OG5_126939 All targets in OG5_126939
Candida albicans one of two potential fatty acid desaturase genes similar to S. cerevisiae OLE1 (YGL055W) delta-9-fatty acid desaturase Get druggable targets OG5_126939 All targets in OG5_126939
Leishmania major stearic acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Leishmania donovani stearic acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Leishmania braziliensis fatty-acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Trypanosoma brucei fatty acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Leishmania braziliensis stearic acid desaturase Get druggable targets OG5_126939 All targets in OG5_126939
Plasmodium berghei stearoyl-CoA desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Leishmania mexicana fatty-acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Trypanosoma congolense fatty acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Trypanosoma cruzi fatty acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Plasmodium vivax stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative Get druggable targets OG5_126939 All targets in OG5_126939
Leishmania donovani fatty-acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Trypanosoma cruzi fatty acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Trypanosoma brucei gambiense fatty acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Leishmania major fatty-acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Trypanosoma cruzi fatty acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Plasmodium knowlesi stearoyl-CoA desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Brugia malayi acyl-CoA desaturase Get druggable targets OG5_126939 All targets in OG5_126939
Onchocerca volvulus Get druggable targets OG5_126939 All targets in OG5_126939
Plasmodium falciparum stearoyl-CoA desaturase Get druggable targets OG5_126939 All targets in OG5_126939
Candida albicans one of two potential fatty acid desaturase genes similar to S. cerevisiae OLE1 (YGL055W) delta-9-fatty acid desaturase Get druggable targets OG5_126939 All targets in OG5_126939
Leishmania infantum fatty-acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Plasmodium yoelii delta-9 fatty acid desaturase Get druggable targets OG5_126939 All targets in OG5_126939
Leishmania infantum stearic acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Neospora caninum fatty acyl-CoA desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Leishmania mexicana stearic acid desaturase, putative Get druggable targets OG5_126939 All targets in OG5_126939
Onchocerca volvulus Get druggable targets OG5_126939 All targets in OG5_126939
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans one of two potential fatty acid desaturase genes similar to S. cerevisiae OLE1 (YGL055W) delta-9 fatty acid desaturase Acyl-CoA desaturase 1   358 aa 317 aa 27.1 %
Candida albicans one of two potential fatty acid desaturase genes similar to S. cerevisiae OLE1 (YGL055W) delta-9 fatty acid desaturase Acyl-CoA desaturase 1   358 aa 317 aa 27.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0037 0.0067
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0104 0.0224 0.0402
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0021 0.0021
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0227 0.0552 0.0992
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.0048 0.0087
Leishmania major protein kinase, putative 0.006 0.0106 0.0185
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0024 0.0012 0.0061
Echinococcus multilocularis sterol regulatory element binding protein 0.0097 0.0207 0.0207
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0048 0.0075 0.0135
Echinococcus granulosus alpha tubulin 0.1523 0.4009 0.6285
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0025 0.0014 0.0022
Mycobacterium leprae Possible regulatory protein 0.0059 0.0104 0.0741
Brugia malayi conserved hypotetical protein 0.0033 0.0034 0.0062
Echinococcus granulosus thioredoxin glutathione reductase 0.011 0.024 0.0376
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0037 0.143
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0716 0.1857 0.1857
Schistosoma mansoni tubulin subunit beta 0.2106 0.5563 0.8721
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0076 0.0148 0.0233
Brugia malayi hypothetical protein 0.0048 0.0075 0.0135
Echinococcus granulosus dnaJ subfamily B 0.0943 0.2461 0.3858
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0093 0.0196 0.0352
Loa Loa (eye worm) hypothetical protein 0.0043 0.0062 0.0112
Onchocerca volvulus 0.0099 0.021 0.0986
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0067 0.0126 0.0227
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0043 0.0061 0.0096
Brugia malayi bZIP transcription factor family protein 0.0284 0.0705 0.1268
Schistosoma mansoni aryl hydrocarbon receptor 0.0226 0.055 0.0862
Echinococcus multilocularis Tubulin beta 2C chain 0.2106 0.5563 0.5563
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0037 0.006
Brugia malayi hypothetical protein 0.0099 0.021 0.0377
Echinococcus multilocularis tubulin alpha chain 0.1523 0.4009 0.4009
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0037 0.006
Schistosoma mansoni thyroid hormone receptor 0.0076 0.0148 0.0233
Loa Loa (eye worm) hypothetical protein 0.005 0.0079 0.0143
Echinococcus granulosus histone lysine methyltransferase setb 0.0104 0.0224 0.0351
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0281 0.0506
Brugia malayi Tubulin alpha chain 0.1523 0.4009 0.7206
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0037 0.0067
Schistosoma mansoni smad1 5 8 and 0.0047 0.0071 0.0111
Schistosoma mansoni ap endonuclease 0.0021 0.0004 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0076 0.0148 0.0267
Brugia malayi Cytochrome P450 family protein 0.0024 0.0012 0.0021
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0131 0.0205
Leishmania major gamma-tubulin 0.1163 0.3048 0.5476
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0036 0.0044 0.0079
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0153 0.0354 0.2704
Echinococcus granulosus tubulin beta 4A class IVa 0.2106 0.5563 0.8721
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0024 0.0012 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0268 0.0481
Loa Loa (eye worm) tubulin alpha-2 chain 0.1523 0.4009 0.7206
Plasmodium falciparum thioredoxin reductase 0.0038 0.0048 0.008
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0131 0.0205
Brugia malayi hypothetical protein 0.0043 0.0061 0.011
Trichomonas vaginalis abcb9, putative 0.0025 0.0014 0.0025
Entamoeba histolytica hypothetical protein 0.0048 0.0075 0.0135
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.012 0.0268 0.0481
Leishmania major beta tubulin 0.2106 0.5563 1
Schistosoma mansoni hypothetical protein 0.0968 0.2528 0.3964
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0037 0.0067
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Loa Loa (eye worm) hypothetical protein 0.0097 0.0207 0.0371
Schistosoma mansoni tubulin subunit alpha 0.0508 0.1301 0.2039
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0076 0.0148 0.0694
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0076 0.0148 0.0267
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0048 0.0075 0.0118
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0024 0.0012 0.0061
Onchocerca volvulus 0.0623 0.1608 0.7636
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0076 0.0148 0.0267
Echinococcus multilocularis CREB binding protein 0.015 0.0346 0.0346
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0219 0.053 0.083
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0067 0.0126 0.0227
Brugia malayi Pax transcription factor protein 2 0.0282 0.0698 0.1254
Loa Loa (eye worm) hypoxia-induced factor 1 0.07 0.1813 0.326
Schistosoma mansoni serine/threonine protein kinase 0.005 0.008 0.0125
Entamoeba histolytica hypothetical protein 0.0048 0.0075 0.0135
Brugia malayi Tubulin gamma chain 0.1163 0.3048 0.5479
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0024 0.0012 0.0061
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0024 0.0012 0.0061
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0008 0.0032
Echinococcus granulosus Tubulin alpha 1 chain 0.1523 0.4009 0.6285
Loa Loa (eye worm) nuclear hormone receptor 0.0033 0.0034 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0268 0.0419
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0007
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.0781 0.1405
Echinococcus granulosus tumor protein p63 0.1556 0.4097 0.6423
Schistosoma mansoni cpg binding protein 0.0102 0.022 0.0345
Mycobacterium ulcerans 6-phosphofructokinase 0.0125 0.0281 0.2141
Onchocerca volvulus Huntingtin homolog 0.0415 0.1054 0.4998
Brugia malayi SPARC precursor 0.0067 0.0126 0.0227
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Schistosoma mansoni smad1 5 8 and 0.0047 0.0071 0.0111
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0184 0.0289
Brugia malayi MH1 domain containing protein 0.0047 0.0071 0.0128
Echinococcus granulosus expressed protein 0.0834 0.2169 0.3401
Echinococcus multilocularis transcription factor Dp 1 0.0045 0.0066 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0156 0.028
Schistosoma mansoni lamin 0.0093 0.0196 0.0307
Brugia malayi Tubulin alpha-2 chain 0.1523 0.4009 0.7206
Loa Loa (eye worm) hypothetical protein 0.09 0.2347 0.4219
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.1131 0.2962 0.5325
Loa Loa (eye worm) tubulin alpha 2 0.0392 0.0993 0.1785
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0076 0.0148 0.0233
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0781 0.1405
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0035 0.0064
Loa Loa (eye worm) tubulin alpha 2 0.1016 0.2655 0.4772
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0024 0.0012 0.0061
Brugia malayi steroid hormone receptor 0.0076 0.0148 0.0267
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0011
Brugia malayi CHE-14 protein 0.0097 0.0207 0.0371
Leishmania major beta tubulin 0.2106 0.5563 1
Leishmania major ATP-dependent phosphofructokinase 0.0125 0.0281 0.0499
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.006 0.0106 0.0191
Trichomonas vaginalis guanylate cyclase, putative 0.0059 0.0104 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0115 0.0206
Echinococcus granulosus smad 0.0047 0.0071 0.0111
Brugia malayi Intermediate filament tail domain containing protein 0.0093 0.0196 0.0352
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0078 0.0122
Brugia malayi follicle stimulating hormone receptor 0.0284 0.0703 0.1265
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0125 0.0281 0.2116
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0012 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0048 0.0087
Echinococcus multilocularis Tubulin beta 2C chain 0.2106 0.5563 0.5563
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0098 0.0177
Loa Loa (eye worm) tubulin alpha 2 0.1016 0.2655 0.4772
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0014 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0076 0.0148 0.0267
Echinococcus granulosus tubulin alpha 3 chain 0.1523 0.4009 0.6285
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0099 0.021 0.0329
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0048 0.0087
Loa Loa (eye worm) pax transcription factor protein 2 0.0282 0.0698 0.1254
Brugia malayi Pre-SET motif family protein 0.0711 0.1844 0.3315
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0034 0.0054
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0024 0.0012 0.0061
Loa Loa (eye worm) CBP-B 0.0152 0.0352 0.0632
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0024 0.0012 0.0061
Echinococcus granulosus expressed conserved protein 0.0213 0.0515 0.0808
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0131 0.0228
Brugia malayi prostaglandin transporter 0.0099 0.021 0.0377
Plasmodium falciparum glutathione reductase 0.0038 0.0048 0.008
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0067 0.0126 0.0227
Echinococcus granulosus sterol regulatory element binding protein 0.0097 0.0207 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.001
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0034 0.0062
Echinococcus multilocularis tumor protein p63 0.1556 0.4097 0.4097
Loa Loa (eye worm) cytochrome P450 0.0024 0.0012 0.0021
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.0062 0.0112
Brugia malayi acyl-CoA desaturase 0.0205 0.0493 0.0885
Schistosoma mansoni multidrug resistance protein 0.0025 0.0014 0.0022
Loa Loa (eye worm) intermediate filament protein 0.0093 0.0196 0.0352
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0049 0.0078 0.014
Echinococcus granulosus microtubule associated protein 2 0.2412 0.6378 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0135 0.0243
Loa Loa (eye worm) 6-phosphofructokinase 0.0125 0.0281 0.0506
Loa Loa (eye worm) hypothetical protein 0.0099 0.021 0.0377
Onchocerca volvulus 0.0033 0.0034 0.0152
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0086 0.0177 0.0177
Echinococcus multilocularis musashi 0.0093 0.0196 0.0196
Echinococcus multilocularis agrin 0.0067 0.0126 0.0126
Trichomonas vaginalis tubulin beta chain, putative 0.0623 0.1608 0.2891
Echinococcus multilocularis ubiquitin specific protease 41 0.0043 0.0062 0.0062
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0251 0.0616 0.4718
Echinococcus granulosus CREB binding protein 0.0036 0.0042 0.0066
Loa Loa (eye worm) hypothetical protein 0.1016 0.2655 0.4772
Schistosoma mansoni microtubule-associated protein tau 0.2412 0.6378 1
Echinococcus granulosus Protein patched homolog 1 0.0097 0.0207 0.0324
Trichomonas vaginalis tubulin, putative 0.0623 0.1608 0.2891
Echinococcus granulosus CREB binding protein 0.0135 0.0306 0.048
Trichomonas vaginalis tubulin beta chain, putative 0.1523 0.4009 0.7206
Echinococcus granulosus lysine specific demethylase 5A 0.0074 0.0145 0.0227
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0781 0.1405
Brugia malayi hypothetical protein 0.0277 0.0684 0.123
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.0144 0.0259
Schistosoma mansoni axis inhibition protein axin 0.0048 0.0075 0.0118
Leishmania major stearic acid desaturase, putative 0.0223 0.0541 0.0966
Echinococcus multilocularis regulator of G protein signaling 3 0.0048 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0043 0.0062 0.0112
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0781 0.1405
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0025 0.0014 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0076 0.0148 0.0267
Plasmodium vivax tubulin alpha chain, putative 0.1523 0.4009 0.7204
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0076 0.0148 0.0267
Echinococcus granulosus Tubulin alpha 1 chain 0.1523 0.4009 0.6285
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.001
Echinococcus multilocularis Tubulin beta 2C chain 0.2106 0.5563 0.5563
Echinococcus multilocularis lipoxygenase domain containing protein 0.0179 0.0425 0.0425
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0025 0.0014 0.0014
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0076 0.0148 0.0233
Trichomonas vaginalis tubulin beta chain, putative 0.1523 0.4009 0.7206
Giardia lamblia Kinase, CMGC MAPK 0.012 0.0268 0.0475
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0038 0.0048 0.008
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0036 0.0044 0.031
Echinococcus multilocularis CREB binding protein 0.0036 0.0042 0.0042
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.0034 0.0062
Leishmania major trypanothione reductase 0.011 0.024 0.0425
Schistosoma mansoni tubulin subunit beta 0.2106 0.5563 0.8721
Schistosoma mansoni retinoic acid receptor RXR 0.0076 0.0148 0.0233
Onchocerca volvulus 0.0099 0.021 0.0986
Echinococcus granulosus tubulin epsilon chain 0.1163 0.3047 0.4777
Trypanosoma cruzi beta tubulin, putative 0.2106 0.5563 1
Loa Loa (eye worm) thioredoxin reductase 0.011 0.024 0.0432
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0105 0.0228 0.0403
Toxoplasma gondii tubulin, putative 0.0032 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0025
Leishmania major epsilon tubulin, putative 0.1163 0.3047 0.5474
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0105 0.0228 0.041
Trypanosoma cruzi epsilon tubulin, putative 0.1163 0.3047 0.5477
Giardia lamblia GTOR 0.0105 0.0228 0.0403
Trypanosoma brucei epsilon tubulin 0.1163 0.3047 0.5477
Giardia lamblia Fructose-bisphosphate aldolase 0.0313 0.0781 0.1399
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0037 0.006
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0024 0.0012 0.0061
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0025 0.0014 0.0077
Loa Loa (eye worm) hypothetical protein 0.0043 0.0061 0.011
Echinococcus granulosus regulator of G protein signaling 7 0.0048 0.0075 0.0118
Echinococcus granulosus tubulin alpha chain 0.1523 0.4009 0.6285
Echinococcus multilocularis thyroid hormone receptor alpha 0.0076 0.0148 0.0148
Loa Loa (eye worm) tubulin beta chain 0.2106 0.5563 1
Echinococcus granulosus nuclear factor of activated T cells 5 0.0086 0.0177 0.0277
Echinococcus granulosus 6 phosphofructokinase 0.0125 0.0281 0.0441
Echinococcus multilocularis expressed protein 0.0834 0.2169 0.2169
Echinococcus multilocularis Tubulin alpha 1 chain 0.1523 0.4009 0.4009
Trypanosoma brucei protein kinase, putative 0.012 0.0268 0.0481
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0045 0.0067 0.0067
Mycobacterium leprae putative cytochrome p450 0.0024 0.0012 0.0029
Trypanosoma brucei beta tubulin 0.1131 0.2962 0.5325
Echinococcus multilocularis beta tubulin 0.2106 0.5563 0.5563
Onchocerca volvulus 0.0059 0.0104 0.0482
Trypanosoma brucei beta tubulin 0.2106 0.5563 1
Entamoeba histolytica tubulin family protein 0.2106 0.5563 1
Leishmania major beta tubulin 0.2106 0.5563 1
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0131 0.0235
Trypanosoma brucei epsilon tubulin 0.1131 0.2962 0.5325
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.001
Echinococcus multilocularis Tubulin beta 2C chain 0.2106 0.5563 0.5563
Echinococcus multilocularis Tubulin alpha 1 chain 0.1523 0.4009 0.4009
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0131 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0099 0.0177
Leishmania major beta tubulin 0.2106 0.5563 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.012 0.0268 0.0268
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0062 0.0112
Schistosoma mansoni regulator of G protein signaling 0.0049 0.0078 0.0122
Echinococcus multilocularis tubulin alpha chain 0.1523 0.4009 0.4009
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0105 0.0228 0.041
Loa Loa (eye worm) hypothetical protein 0.0033 0.0035 0.0064
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0014 0.0022
Echinococcus multilocularis tubulin subunit TubB 0.1523 0.4009 0.4009
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.0048 0.0087
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0033 0.0034 0.0062
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0153 0.0275
Echinococcus multilocularis axis inhibition protein axin 0.0048 0.0075 0.0075
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0004 0.0007
Mycobacterium tuberculosis Probable dehydrogenase 0.0251 0.0616 0.4718
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0104 0.0224 0.0351
Schistosoma mansoni lipoxygenase 0.0393 0.0995 0.1561
Echinococcus granulosus ecdysone induced protein 78C 0.0076 0.0148 0.0233
Echinococcus granulosus Polycystic kidney disease protein 0.0179 0.0425 0.0667
Echinococcus multilocularis tubulin beta 1 chain 0.2106 0.5563 0.5563
Schistosoma mansoni multidrug resistance protein 0.0025 0.0014 0.0022
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0037 0.006
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0025 0.0014 0.0022
Brugia malayi sodium-independent organic anion transporter family protein 0.0099 0.021 0.0377
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0187 0.0336
Brugia malayi Cell division protein ftsZ 0.0508 0.1301 0.2338
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.0034 0.0034
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0251 0.0616 0.4718
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0023 0.0008 0.0032
Toxoplasma gondii NADPH-glutathione reductase 0.0038 0.0048 0.0087
Schistosoma mansoni niemann-pick C1 (NPC1) 0.023 0.0561 0.088
Plasmodium falciparum stearoyl-CoA desaturase 0.0205 0.0493 0.0879
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0041 0.0074
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0004 0.0006
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0153 0.0275
Leishmania major zeta tubulin, putative 0.084 0.2186 0.3926
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0059 0.0104 0.0186
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0279 0.069 0.5279
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0077 0.0153 0.0268
Brugia malayi hypoxia-induced factor 1 0.07 0.1813 0.326
Schistosoma mansoni 6-phosphofructokinase 0.0125 0.0281 0.0441
Schistosoma mansoni tubulin subunit beta 0.0508 0.1301 0.2039
Schistosoma mansoni smad 0.0021 0.0002 0.0004
Loa Loa (eye worm) tubulin beta-1 chain 0.2106 0.5563 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0099 0.0177
Echinococcus granulosus Tubulin beta 2C chain 0.2106 0.5563 0.8721
Trypanosoma brucei alpha tubulin 0.1523 0.4009 0.7206
Schistosoma mansoni agrin 0.0067 0.0126 0.0198
Schistosoma mansoni regulator of G protein signaling 0.0048 0.0075 0.0118
Mycobacterium leprae cell division protein FtsZ 0.0508 0.1301 1
Echinococcus multilocularis Smad4 0.0047 0.0071 0.0071
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0033 0.0035 0.0055
Brugia malayi CXXC zinc finger family protein 0.0097 0.0205 0.0369
Trichomonas vaginalis tubulin gamma chain, putative 0.1163 0.3047 0.5477
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0099 0.021 0.0377
Schistosoma mansoni hypothetical protein 0.0053 0.0087 0.0136
Echinococcus multilocularis lipoxygenase domain containing protein 0.0179 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0087 0.0179 0.0321
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.09 0.2347 0.4219
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0025 0.0014 0.0025
Echinococcus multilocularis regulator of G protein signaling 3 0.0048 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0094 0.0197 0.0309
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.001
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0076 0.0148 0.0267
Echinococcus granulosus axis inhibition protein axin 0.0048 0.0075 0.0118
Echinococcus granulosus tubulin alpha chain 0.1523 0.4009 0.6285
Brugia malayi multidrug resistance protein 3 0.0025 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0062 0.0112
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0034 0.0037 0.0058
Echinococcus multilocularis protein dispatched 1 0.0111 0.0243 0.0243
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0038 0.0048 0.008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Loa Loa (eye worm) hypothetical protein 0.0076 0.0148 0.0267
Leishmania major fatty-acid desaturase, putative 0.0223 0.0541 0.0966
Loa Loa (eye worm) hypothetical protein 0.0076 0.0148 0.0267
Echinococcus multilocularis tubulin delta chain 0.0508 0.1301 0.1301
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0048 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0022 0.004
Leishmania major beta tubulin 0.2106 0.5563 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0037 0.0258
Plasmodium falciparum ataxin-2 like protein, putative 0.0117 0.0259 0.046
Trichomonas vaginalis tubulin beta chain, putative 0.1523 0.4009 0.7206
Brugia malayi nuclear hormone receptor 0.0076 0.0148 0.0267
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0077 0.0153 0.0153
Brugia malayi hypothetical protein 0.0179 0.0425 0.0765
Mycobacterium ulcerans hypothetical protein 0.0023 0.0008 0.0032
Trichomonas vaginalis ABC transporter, putative 0.0025 0.0014 0.0025
Echinococcus granulosus Tubulin beta 2C chain 0.2106 0.5563 0.8721
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0004 0.0004
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.0781 0.1405
Echinococcus multilocularis geminin 0.0968 0.2528 0.2528
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0025 0.0014 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0508 0.1301 0.2338
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0077 0.0153 0.0275
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0035 0.0041 0.0074
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0014 0.0076
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0077 0.0153 0.0275
Brugia malayi Regulator of G protein signaling domain containing protein 0.0048 0.0075 0.0135
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0034 0.0054
Echinococcus granulosus Tubulin alpha 1 chain 0.1523 0.4009 0.6285
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0053 0.0087 0.0136
Loa Loa (eye worm) Smad1 0.0047 0.0071 0.0128
Schistosoma mansoni alpha tubulin 0.1523 0.4009 0.6285
Echinococcus granulosus Tubulin beta 2C chain 0.2106 0.5563 0.8721
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0024 0.0012 0.0061
Brugia malayi hypothetical protein 0.0048 0.0075 0.0135
Onchocerca volvulus Putative organic anion transporter 0.0099 0.021 0.0986
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0184 0.0289
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0184 0.0331
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0251 0.0616 0.4718
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.0145 0.0227
Onchocerca volvulus Bile acid receptor homolog 0.0076 0.0148 0.0694
Echinococcus multilocularis peroxisome assembly protein 26 0.1523 0.4009 0.4009
Echinococcus multilocularis mothers against decapentaplegic 2 0.0021 0.0002 0.0002
Trypanosoma cruzi target of rapamycin kinase 3 0.0084 0.0171 0.0307
Echinococcus multilocularis isocitrate dehydrogenase 0.0036 0.0044 0.0044
Trichomonas vaginalis tubulin epsilon chain, putative 0.1523 0.4009 0.7206
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0014 0.0076
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0023 0.0008 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0156 0.028
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0048 0.0075 0.0135
Schistosoma mansoni RAR-like nuclear receptor 0.0076 0.0148 0.0233
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0251 0.0616 0.4718
Schistosoma mansoni hypothetical protein 0.0179 0.0425 0.0667
Trypanosoma cruzi tubulin delta chain 0.0706 0.183 0.3291
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0206 0.0495 0.0776
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0048 0.0075 0.0118
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0038 0.0048 0.0345
Schistosoma mansoni single-minded 0.0226 0.055 0.0862
Brugia malayi tubulin alpha chain - mouse 0.1523 0.4009 0.7206
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0035 0.0041 0.0064
Brugia malayi Cytochrome P450 family protein 0.0074 0.0144 0.0259
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0279 0.069 0.5293
Schistosoma mansoni hypothetical protein 0.0297 0.074 0.1159
Toxoplasma gondii protease inhibitor PI2 0.0067 0.0126 0.0227
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0004 0.0007
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0024 0.0012 0.0021
Loa Loa (eye worm) CYP4Cod1 0.0074 0.0144 0.0259
Trichomonas vaginalis taga, putative 0.0025 0.0014 0.0025
Onchocerca volvulus 0.0076 0.0148 0.0694
Onchocerca volvulus Huntingtin homolog 0.0415 0.1054 0.4998
Onchocerca volvulus 0.0093 0.0196 0.0919
Entamoeba histolytica P-glycoprotein-5 0.0025 0.0014 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0097 0.0207 0.0371
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.001
Echinococcus granulosus peroxisome assembly protein 26 0.1523 0.4009 0.6285
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0035 0.0064
Entamoeba histolytica P-glycoprotein-2 0.0025 0.0014 0.0025
Echinococcus multilocularis Regulator of G protein signaling 20 0.0048 0.0075 0.0075
Trichomonas vaginalis tubulin beta chain, putative 0.2106 0.5563 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.0048 0.008
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0048 0.0075 0.0075
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0028 0.0021 0.0039
Echinococcus multilocularis tubulin alpha chain 0.1523 0.4009 0.4009
Echinococcus multilocularis neuropeptide receptor A26 0.107 0.2801 0.2801
Onchocerca volvulus 0.0104 0.0224 0.1053
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0024 0.0012 0.0061
Brugia malayi PXA domain containing protein 0.0048 0.0075 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.017 0.0306
Toxoplasma gondii beta-tubulin, putative 0.2106 0.5563 1
Schistosoma mansoni DNA helicase recq5 0.0033 0.0035 0.0055
Brugia malayi hypothetical protein 0.0076 0.0149 0.0267
Trichomonas vaginalis tubulin alpha chain, putative 0.1131 0.2962 0.5325
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0062 0.0112
Echinococcus granulosus tubulin alpha 0.1131 0.2962 0.4644
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0025 0.0014 0.0025
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0004 0.0007
Trypanosoma brucei tubulin gamma chain 0.1163 0.3048 0.5479
Plasmodium falciparum glutathione reductase 0.011 0.024 0.0425
Giardia lamblia Delta tubulin 0.0508 0.1301 0.2333
Schistosoma mansoni transcription factor LCR-F1 0.0206 0.0495 0.0776
Giardia lamblia Beta tubulin 0.2106 0.5563 1
Echinococcus multilocularis protein patched 0.0097 0.0207 0.0207
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.0034 0.0054
Toxoplasma gondii alpha-tubulin I, putative 0.1523 0.4009 0.7206
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.0043 0.0078
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.0034 0.0062
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0024 0.0012 0.0061
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0038 0.0048 0.0087
Loa Loa (eye worm) phosphofructokinase 0.0125 0.0281 0.0506
Trichomonas vaginalis tubulin, putative 0.2106 0.5563 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.021 0.0377
Loa Loa (eye worm) glutathione reductase 0.011 0.024 0.0432
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0053 0.0087 0.0087
Loa Loa (eye worm) MH2 domain-containing protein 0.0047 0.0071 0.0128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0076 0.0148 0.0267
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0135
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0281 0.0506
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0024 0.0012 0.0061
Entamoeba histolytica hypothetical protein 0.0206 0.0495 0.089
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0087 0.0179 0.135
Trichomonas vaginalis tubulin, putative 0.054 0.1386 0.2492
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0098 0.0177
Brugia malayi photoreceptor-specific nuclear receptor 0.0076 0.0148 0.0267
Echinococcus multilocularis ATP binding cassette sub family B 0.0025 0.0013 0.0013
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0251 0.0616 0.4701
Echinococcus granulosus aryl hydrocarbon receptor 0.0059 0.0104 0.0162
Schistosoma mansoni rab6-interacting 0.0179 0.0425 0.0667
Schistosoma mansoni intermediate filament proteins 0.0093 0.0196 0.0307
Loa Loa (eye worm) hypothetical protein 0.0059 0.0104 0.0186
Loa Loa (eye worm) tubulin alpha chain 0.1523 0.4009 0.7206
Brugia malayi MH2 domain containing protein 0.0021 0.0002 0.0004
Echinococcus multilocularis follistatin 0.0067 0.0126 0.0126
Echinococcus granulosus cpg binding protein 0.0102 0.022 0.0345
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0024 0.0012 0.0061
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0059 0.0104 0.0162
Onchocerca volvulus 0.0223 0.0543 0.2568
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Onchocerca volvulus 0.0228 0.0554 0.2624
Echinococcus multilocularis tubulin alpha 3 chain 0.1523 0.4009 0.4009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0061 0.011
Schistosoma mansoni thyroid hormone receptor 0.0076 0.0148 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0508 0.1301 0.2338
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0034 0.0062
Trichomonas vaginalis tubulin alpha chain, putative 0.0623 0.1608 0.2891
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0034 0.0152
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0037 0.0067
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0711 0.1844 0.3315
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0038 0.0048 0.0048
Trypanosoma cruzi alpha tubulin, putative 0.1523 0.4009 0.7206
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0038 0.0048 0.0345
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0206 0.0495 0.0495
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0075 0.0135
Schistosoma mansoni cytochrome P450 0.0024 0.0012 0.0018
Schistosoma mansoni zinc finger protein 0.0033 0.0034 0.0054
Schistosoma mansoni tubulin subunit beta 0.2106 0.5563 0.8721
Schistosoma mansoni hypothetical protein 0.0231 0.0563 0.0883
Schistosoma mansoni coup transcription factor 0.0076 0.0148 0.0233
Entamoeba histolytica P-glycoprotein-2 0.0025 0.0014 0.0025
Leishmania major beta tubulin 0.2106 0.5563 1
Brugia malayi F/Y-rich N-terminus family protein 0.0033 0.0036 0.0064
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0076 0.0148 0.0233
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0781 0.1405
Echinococcus multilocularis mitogen activated protein kinase 0.012 0.0268 0.0268
Loa Loa (eye worm) tubulin alpha-3 chain 0.09 0.2347 0.4219
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0508 0.1301 0.2338
Brugia malayi Tubulin alpha chain 0.0508 0.1301 0.2338
Echinococcus multilocularis tubulin alpha chain 0.1523 0.4009 0.4009
Plasmodium vivax SET domain protein, putative 0.0104 0.0224 0.0396
Leishmania major beta tubulin 0.2106 0.5563 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0179 0.0425 0.0667
Loa Loa (eye worm) multidrug resistance protein 3 0.0025 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Loa Loa (eye worm) hypothetical protein 0.0067 0.0126 0.0227
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0044 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0075 0.0135
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0014 0.0018
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0025 0.0014 0.0025
Trichomonas vaginalis tubulin beta chain, putative 0.1523 0.4009 0.7206
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0076 0.0148 0.0267
Loa Loa (eye worm) CXXC zinc finger family protein 0.0097 0.0205 0.0369
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0014 0.0024
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0037 0.0067
Schistosoma mansoni multidrug resistance protein 0.0025 0.0014 0.0022
Trichomonas vaginalis glutathione reductase, putative 0.0038 0.0048 0.0087
Brugia malayi cytochrome P450 0.0024 0.0012 0.0021
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Leishmania major beta tubulin 0.2106 0.5563 1
Brugia malayi nuclear receptor NHR-88 0.0033 0.0034 0.0062
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0059 0.0104 0.0186
Schistosoma mansoni axis inhibition protein axin 0.0048 0.0075 0.0118
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0105 0.0228 0.0357
Plasmodium falciparum ataxin-2 like protein, putative 0.0117 0.0259 0.046
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0059 0.0104 0.0186
Echinococcus granulosus Niemann Pick C1 protein 0.0324 0.0812 0.1272
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0024 0.0012 0.0014
Onchocerca volvulus 0.0179 0.0425 0.2011
Leishmania major beta tubulin 0.2106 0.5563 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.0048 0.0087
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0077 0.0153 0.024
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0076 0.0148 0.0233
Leishmania major cytochrome p450-like protein 0.0074 0.0144 0.0253
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0131 0.0978
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.0034 0.0054
Schistosoma mansoni hypothetical protein 0.0094 0.0197 0.0309
Entamoeba histolytica tubulin alpha chain, putative 0.1523 0.4009 0.7206
Loa Loa (eye worm) tubulin beta-4 chain 0.2106 0.5563 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0076 0.0148 0.0148
Echinococcus granulosus regulator of G protein signaling 3 0.0048 0.0075 0.0118
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0284 0.0703 0.1265
Brugia malayi hypothetical protein 0.0099 0.021 0.0377
Echinococcus multilocularis lysine specific demethylase 5A 0.0069 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0268 0.0481
Echinococcus granulosus beta-adrenergic receptor kinase 0.0049 0.0078 0.0122
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0033 0.0034 0.0034
Leishmania major hypothetical protein, conserved 0.0117 0.0259 0.046
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0062 0.0112
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0279 0.069 0.5293
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0104 0.0224 0.0351
Loa Loa (eye worm) acyl-CoA desaturase 0.0205 0.0493 0.0885
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0025 0.0014 0.0014
Schistosoma mansoni tubulin subunit epsilon 0.1163 0.3047 0.4777
Echinococcus multilocularis tubulin subunit beta 0.2106 0.5563 0.5563
Entamoeba histolytica tubulin alpha-1 chain 0.1523 0.4009 0.7206
Trypanosoma cruzi PAB1-binding protein , putative 0.0117 0.0259 0.0466
Echinococcus granulosus mitogen activated protein kinase 3 0.012 0.0268 0.0419
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Echinococcus multilocularis mothers against decapentaplegic 5 0.0047 0.0071 0.0071
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0025 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0067 0.0126 0.0227
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0044 0.0065 0.0111
Brugia malayi beta-tubulin, identical 0.2106 0.5563 1
Brugia malayi hypothetical protein 0.0223 0.0543 0.0975
Trichomonas vaginalis mercuric reductase, putative 0.0038 0.0048 0.0087
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0025 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0093 0.0196 0.0352
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0076 0.0148 0.0233
Echinococcus granulosus tubulin alpha chain 0.1523 0.4009 0.6285
Loa Loa (eye worm) hypothetical protein 0.0415 0.1054 0.1894
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0025 0.0014 0.0025
Brugia malayi hypothetical protein 0.0415 0.1054 0.1894
Plasmodium vivax tubulin beta chain, putative 0.2106 0.5563 1
Echinococcus granulosus tubulin alpha chain 0.1523 0.4009 0.6285
Brugia malayi MH2 domain containing protein 0.0683 0.1768 0.3178
Schistosoma mansoni tubulin subunit alpha 0.1523 0.4009 0.6285
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0025 0.0014 0.0025
Schistosoma mansoni tubulin subunit delta 0.0508 0.1301 0.2039
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0024 0.0012 0.0061
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0036 0.0044 0.0044
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0067 0.0126 0.0227
Toxoplasma gondii target of rapamycin (TOR), putative 0.0078 0.0156 0.028
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0061 0.0096
Trypanosoma cruzi PAB1-binding protein , putative 0.0117 0.0259 0.0466
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.012 0.0268 0.0475
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0037 0.0067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0759 0.197 0.3542
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0033 0.0035 0.0057
Schistosoma mansoni follistatin 0.0067 0.0126 0.0198
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0043 0.0061 0.0061
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0024 0.0012 0.0061
Loa Loa (eye worm) hypothetical protein 0.0277 0.0684 0.123
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0087 0.0179 0.0321
Brugia malayi bHLH-PAS transcription factor 0.0167 0.0393 0.0707
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0035 0.0041 0.0074
Echinococcus granulosus neuropeptide s receptor 0.107 0.2801 0.4391
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0087 0.0179 0.0315
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0113 0.0203
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0281 0.0506
Brugia malayi MH1 domain containing protein 0.0026 0.0015 0.0028
Echinococcus multilocularis smad 0.0047 0.0071 0.0071
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0716 0.1857 0.2911
Echinococcus multilocularis transfer RNA-Lys 0.0167 0.0393 0.0393
Brugia malayi jmjC domain containing protein 0.0069 0.013 0.0234
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.0034 0.0054
Giardia lamblia Epsilon tubulin 0.0539 0.1385 0.2485
Loa Loa (eye worm) hypothetical protein 0.0067 0.0126 0.0227
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0105 0.0228 0.041
Brugia malayi Tubulin alpha-2 chain 0.1523 0.4009 0.7206
Brugia malayi Niemann-Pick C1 protein precursor 0.0227 0.0552 0.0992
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0025 0.0014 0.0025
Schistosoma mansoni tubulin subunit beta 0.2106 0.5563 0.8721
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0025 0.0014 0.0025
Plasmodium falciparum LCCL domain-containing protein 0.0179 0.0425 0.0758
Schistosoma mansoni fkbp-rapamycin associated protein 0.002 0.000000013964 0.000000021893
Trichomonas vaginalis ABC transporter, putative 0.0025 0.0014 0.0025
Trypanosoma cruzi tubulin gamma chain 0.1163 0.3048 0.5479
Brugia malayi glutathione reductase 0.011 0.024 0.0432
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0074 0.0144 0.1083
Plasmodium vivax thioredoxin reductase, putative 0.011 0.024 0.0425
Echinococcus multilocularis tubulin alpha 1C chain 0.1523 0.4009 0.4009
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0508 0.1301 1
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0049 0.0078 0.014
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0076 0.0148 0.0267
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.013 0.0204
Schistosoma mansoni smad1 5 8 and 0.0047 0.0071 0.0111
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0005 0.001
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0024 0.0012 0.0061
Echinococcus granulosus cytochrome P450 2K1 0.0024 0.0012 0.0018
Echinococcus multilocularis CREB binding protein 0.0036 0.0042 0.0042
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0034 0.0152
Brugia malayi ecdysteroid receptor 0.0076 0.0148 0.0267
Echinococcus multilocularis Niemann Pick C1 protein 0.0324 0.0812 0.0812
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0145 0.0261
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0062 0.0098
Loa Loa (eye worm) hypothetical protein 0.0117 0.0259 0.0466
Echinococcus multilocularis ecdysone induced protein 78C 0.0076 0.0148 0.0148
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0014 0.0018
Toxoplasma gondii beta-1 tubulin, putative 0.2106 0.5563 1
Echinococcus multilocularis RUN 0.0179 0.0425 0.0425
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0156 0.028
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0004 0.0007
Schistosoma mansoni cpg binding protein 0.0102 0.022 0.0345
Mycobacterium ulcerans endonuclease IV 0.0087 0.0179 0.135
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.0034 0.0062
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0076 0.0148 0.0148
Leishmania major beta tubulin 0.2106 0.5563 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.2106 0.5563 1
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0281 0.0506
Schistosoma mansoni DNA helicase recq1 0.0033 0.0035 0.0055
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0623 0.1608 0.2891
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0067 0.0126 0.0227
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.0034 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0075 0.0135
Echinococcus multilocularis regulator of G protein signaling 0.0048 0.0075 0.0075
Onchocerca volvulus 0.0093 0.0196 0.0919
Trypanosoma brucei cytochrome P450, putative 0.0074 0.0144 0.0259
Giardia lamblia Beta tubulin 0.2106 0.5563 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0131 0.0978
Entamoeba histolytica hypothetical protein 0.0206 0.0495 0.089
Echinococcus multilocularis expressed conserved protein 0.0213 0.0515 0.0515
Echinococcus multilocularis mothers against decapentaplegic 6 0.0021 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0076 0.0148 0.0267
Schistosoma mansoni organic anion transporter 0.0099 0.021 0.0329
Trypanosoma cruzi MFS transporter, putative 0.0099 0.021 0.0377
Echinococcus granulosus intermediate filament protein 0.0093 0.0196 0.0307
Trypanosoma brucei epsilon tubulin 0.1163 0.3047 0.5477
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0156 0.028
Loa Loa (eye worm) hypothetical protein 0.0076 0.0148 0.0267
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0076 0.0148 0.0233
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0099 0.0177
Loa Loa (eye worm) alpha-tubulin 0.1523 0.4009 0.7206
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0024 0.0012 0.0061
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0135
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0044 0.0079
Loa Loa (eye worm) hypothetical protein 0.0227 0.0552 0.0992
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0105 0.0228 0.0403
Leishmania major beta tubulin 0.2106 0.5563 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0179 0.0425 0.0425
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0099 0.021 0.021
Plasmodium vivax glutathione reductase, putative 0.011 0.024 0.0425
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0105 0.0228 0.0357
Schistosoma mansoni CREB-binding protein 2 0.0219 0.053 0.083
Entamoeba histolytica hypothetical protein 0.0206 0.0495 0.089
Trichomonas vaginalis ABC transporter, putative 0.0025 0.0014 0.0025
Schistosoma mansoni tubulin subunit beta 0.2106 0.5563 0.8721
Onchocerca volvulus 0.0282 0.0698 0.3306
Entamoeba histolytica P-glycoprotein 5, putative 0.0025 0.0014 0.0025
Loa Loa (eye worm) doublecortin family protein 0.0179 0.0425 0.0765
Trypanosoma cruzi cytochrome P450, putative 0.0074 0.0144 0.0259
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0005 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0156 0.028
Brugia malayi Pre-SET motif family protein 0.0104 0.0224 0.0402
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0024 0.0012 0.0061
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0059 0.0104 0.0186
Echinococcus multilocularis survival motor neuron protein 1 0.0277 0.0684 0.0684
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.0034 0.0054
Brugia malayi ABC transporter family protein 0.0025 0.0014 0.0025
Plasmodium vivax multidrug resistance protein 1, putative 0.0025 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0089 0.0184 0.0331
Brugia malayi MH2 domain containing protein 0.0047 0.0071 0.0128
Echinococcus granulosus tubulin gamma 1 chain 0.1163 0.3048 0.4779
Echinococcus multilocularis regulator of G protein signaling 7 0.0048 0.0075 0.0075
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0073 0.0132
Leishmania major p-glycoprotein 0.0025 0.0014 0.0018
Loa Loa (eye worm) tubulin beta-2A chain 0.2106 0.5563 1
Schistosoma mansoni loxhd1 0.0179 0.0425 0.0667
Trichomonas vaginalis tubulin, putative 0.0623 0.1608 0.2891
Leishmania major protein kinase, putative 0.006 0.0106 0.0185
Plasmodium vivax ataxin-2 like protein, putative 0.0117 0.0259 0.046
Echinococcus granulosus neuropeptide receptor A26 0.107 0.2801 0.4391
Loa Loa (eye worm) hypothetical protein 0.1523 0.4009 0.7206
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Echinococcus granulosus tubulin subunit TubB 0.1523 0.4009 0.6285
Brugia malayi sodium-independent organic anion transporter family protein 0.0099 0.021 0.0377
Brugia malayi Cytochrome P450 family protein 0.0024 0.0012 0.0021
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0036 0.0044 0.0069
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0038 0.0048 0.0076
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.011 0.024 0.1822
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0076 0.0148 0.0148
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0209 0.0505 0.0792
Loa Loa (eye worm) hypothetical protein 0.0103 0.022 0.0396
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0004 0.0007
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0156 0.028
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0062 0.0112
Trichomonas vaginalis tubulin alpha chain, putative 0.0623 0.1608 0.2891
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0073 0.0073
Echinococcus multilocularis beta tubulin 0.2106 0.5563 0.5563
Giardia lamblia Sgs1 DNA helicase, putative 0.0033 0.0035 0.0057
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0084 0.0171 0.0307
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.0043 0.0078
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0062 0.0098
Leishmania major beta tubulin 0.2106 0.5563 1
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0024 0.0012 0.0061
Echinococcus granulosus lamin 0.0093 0.0196 0.0307
Loa Loa (eye worm) MH1 domain-containing protein 0.0047 0.0071 0.0128
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0048 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0076 0.0148 0.0267
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0024 0.0012 0.0061
Brugia malayi TAZ zinc finger family protein 0.0219 0.053 0.0952
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0038 0.0048 0.0345
Leishmania major beta tubulin 0.2106 0.5563 1
Onchocerca volvulus Putative organic anion transporter 0.0099 0.021 0.0986
Schistosoma mansoni hypothetical protein 0.0206 0.0495 0.0776
Brugia malayi intermediate filament protein 0.0093 0.0196 0.0352
Echinococcus granulosus Solute carrier organic anion transporter family 0.0099 0.021 0.0329
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0045 0.0067 0.0105
Mycobacterium tuberculosis Cell division protein FtsZ 0.0508 0.1301 1
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0129 0.0232
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0076 0.0148 0.0148
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0044 0.0044
Schistosoma mansoni jun-related protein 0.0231 0.0563 0.0883
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0076 0.0148 0.0267
Echinococcus granulosus CREB binding protein 0.0036 0.0042 0.0066
Giardia lamblia Beta tubulin 0.2106 0.5563 1
Brugia malayi Steroid receptor seven-up type 2 0.0076 0.0148 0.0267
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0012 0.0021
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0035 0.0041 0.0064
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0038 0.0048 0.0087
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0037 0.0067
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0038 0.0048 0.0087
Trichomonas vaginalis guanylate cyclase, putative 0.0059 0.0104 0.0186
Brugia malayi sodium-independent organic anion transporter family protein 0.0099 0.021 0.0377
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0024 0.0012 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0076 0.0148 0.0267
Echinococcus multilocularis FTZ F1 alpha 0.0076 0.0148 0.0148
Schistosoma mansoni tubulin subunit alpha 0.1523 0.4009 0.6285
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0024 0.0012 0.0061
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0025 0.0014 0.0022
Echinococcus granulosus tubulin alpha 1C chain 0.1523 0.4009 0.6285
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0024 0.0012 0.0061
Schistosoma mansoni regulator of G protein signaling 0.0048 0.0075 0.0118
Loa Loa (eye worm) DR-78 0.0033 0.0034 0.0062
Schistosoma mansoni jumonji domain containing protein 0.0069 0.013 0.0204
Brugia malayi MAP kinase sur-1 0.012 0.0268 0.0481
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.0144 0.0259
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0073 0.0132
Loa Loa (eye worm) hypothetical protein 0.0119 0.0265 0.0476
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0048 0.0087
Brugia malayi nuclear hormone receptor 0.0033 0.0034 0.0062
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0025 0.0014 0.0025
Onchocerca volvulus 0.0033 0.0034 0.0152
Echinococcus granulosus lipoxygenase domain containing protein 0.0179 0.0425 0.0667
Schistosoma mansoni blooms syndrome DNA helicase 0.003 0.0028 0.0044
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.0048 0.0087
Trypanosoma cruzi fatty acid desaturase, putative 0.0205 0.0493 0.0885
Toxoplasma gondii exonuclease III APE 0.0021 0.0004 0.0007
Loa Loa (eye worm) BEN-1 protein 0.2106 0.5563 1
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0024 0.0012 0.0061
Brugia malayi hypothetical protein 0.0033 0.0034 0.0062
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0059 0.0104 0.5447
Trichomonas vaginalis abcb9, putative 0.0025 0.0014 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0024 0.0012 0.0061
Leishmania major beta tubulin 0.2106 0.5563 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0148 0.0267
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0034 0.0054
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0087 0.0179 0.1322
Onchocerca volvulus 0.0056 0.0097 0.0452
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0078 0.0122
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0025 0.0014 0.0014
Brugia malayi Raf kinase 0.005 0.008 0.0143
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0014 0.0076
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0125 0.0281 0.2141
Echinococcus multilocularis aryl hydrocarbon receptor 0.0059 0.0104 0.0104
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0076 0.0148 0.0233
Loa Loa (eye worm) hypothetical protein 0.0099 0.021 0.0377
Trypanosoma cruzi cytochrome P450, putative 0.0074 0.0144 0.0259
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0048 0.0075 0.0118
Schistosoma mansoni hypothetical protein 0.0094 0.0197 0.0309
Echinococcus granulosus single minded 2 0.0167 0.0393 0.0616
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0067 0.0126 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0075 0.0135
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0025 0.0014 0.0011
Schistosoma mansoni steroid hormone receptor ad4bp 0.0076 0.0148 0.0233
Echinococcus granulosus CREB binding protein 0.0219 0.053 0.083
Brugia malayi A-kinase anchor protein 10, precursor 0.0048 0.0075 0.0135
Leishmania major beta tubulin 0.2106 0.5563 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0004 0.0007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0076 0.0148 0.0233
Loa Loa (eye worm) beta-tubulin 0.2106 0.5563 1
Schistosoma mansoni rab6-interacting 0.0179 0.0425 0.0667
Brugia malayi mothers against decapentaplegic homolog 3 0.0021 0.0002 0.0004
Echinococcus granulosus beta tubulin 0.2106 0.5563 0.8721
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0049 0.0078 0.014
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.002 0.0037
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0047 0.0071 0.0071
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0105 0.0228 0.041
Echinococcus granulosus geminin 0.0968 0.2528 0.3964
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0025 0.0014 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0041 0.0074
Echinococcus multilocularis 6 phosphofructokinase 0.0125 0.0281 0.0281
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0037 0.0067
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.0034 0.0034
Toxoplasma gondii LsmAD domain-containing protein 0.0117 0.0259 0.0466
Trypanosoma cruzi fatty acid desaturase, putative 0.0205 0.0493 0.0885
Onchocerca volvulus 0.0167 0.0393 0.1859
Loa Loa (eye worm) hypothetical protein 0.0099 0.021 0.0377
Echinococcus granulosus tubulin alpha chain 0.1523 0.4009 0.6285
Schistosoma mansoni cellular tumor antigen P53 0.0228 0.0554 0.0869
Trichomonas vaginalis tubulin alpha chain, putative 0.0623 0.1608 0.2891
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0067 0.0126 0.0227
Loa Loa (eye worm) tubulin gamma chain 0.1163 0.3048 0.5479
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0025 0.0014 0.0025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0781 0.1405
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0076 0.0148 0.0267
Schistosoma mansoni survival motor neuron protein 0.0056 0.0097 0.0153
Loa Loa (eye worm) transcription factor SMAD2 0.0683 0.1768 0.3178
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0024 0.0012 0.0061
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.006 0.0106 0.0191
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.012 0.0268 0.0481
Toxoplasma gondii thioredoxin reductase 0.011 0.024 0.0432
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0097 0.0175
Toxoplasma gondii beta tubulin 0.2106 0.5563 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0025 0.0014 0.0025
Toxoplasma gondii histone lysine methyltransferase SET1 0.0191 0.0457 0.0821
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0028 0.0021 0.0039
Schistosoma mansoni alpha tubulin 0.1523 0.4009 0.6285
Onchocerca volvulus 0.0089 0.0184 0.0865
Plasmodium vivax tubulin gamma chain, putative 0.1163 0.3048 0.5476
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0033 0.0035 0.0035
Schistosoma mansoni alpha tubulin 0.1523 0.4009 0.6285
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0067 0.0126 0.0227
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0765
Brugia malayi Tubulin beta chain 0.0508 0.1301 0.2338
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0025 0.0014 0.0014
Treponema pallidum cell division protein FtsZ 0.0508 0.1301 1
Echinococcus granulosus bloom syndrome protein 0.0047 0.0073 0.0115
Brugia malayi hypothetical protein 0.0759 0.197 0.3542
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0062 0.0062
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0105 0.0228 0.041
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0059 0.0104 0.0186
Echinococcus multilocularis microtubule associated protein 2 0.2412 0.6378 0.6378
Loa Loa (eye worm) hypothetical protein 0.0228 0.0554 0.0996
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0153 0.0354 0.2704
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0156 0.028
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Loa Loa (eye worm) hypothetical protein 0.0099 0.021 0.0377
Mycobacterium ulcerans putative regulatory protein 0.0167 0.0393 0.3003
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0038 0.0048 0.0087
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0035 0.0041 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0078 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0024 0.0012 0.0061
Echinococcus granulosus regulator of G protein signaling 3 0.0048 0.0075 0.0118
Echinococcus granulosus ubiquitin specific protease 41 0.0043 0.0062 0.0098
Trypanosoma brucei alpha tubulin 0.1523 0.4009 0.7206
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0062 0.0112
Plasmodium falciparum alpha tubulin 1 0.1523 0.4009 0.7204
Trichomonas vaginalis tubulin epsilon chain, putative 0.0508 0.1301 0.2338
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0135
Schistosoma mansoni patched 1 0.0097 0.0207 0.0324
Mycobacterium ulcerans epimerase 0.0023 0.0008 0.0032
Loa Loa (eye worm) phosphatidylinositol 3 0.0035 0.0041 0.0074
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0131 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0268 0.0481
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0076 0.0148 0.0267
Brugia malayi jmjC domain containing protein 0.0074 0.0145 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0113 0.0203
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.006 0.0106 0.0191
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0014 0.0024
Brugia malayi nuclear receptor NHR-88 0.0076 0.0148 0.0267
Loa Loa (eye worm) isocitrate dehydrogenase 0.0036 0.0044 0.0079
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0028 0.0021 0.0021
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0059 0.0104 0.0186
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0025 0.0014 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0115 0.0206
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0076 0.0148 0.0267
Leishmania major beta tubulin 0.2106 0.5563 1
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0024 0.0012 0.0061
Loa Loa (eye worm) phosphatidylinositol 3 0.0105 0.0228 0.041
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1016 0.2655 0.4772
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0025 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0013 0.0023
Trypanosoma brucei alpha tubulin 0.1523 0.4009 0.7206
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0781 0.1405
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0105 0.0228 0.0228
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0067 0.0126 0.0227
Brugia malayi 6-phosphofructokinase 0.0125 0.0281 0.0506
Trichomonas vaginalis set domain proteins, putative 0.0809 0.2105 0.3785
Loa Loa (eye worm) hypothetical protein 0.0104 0.0224 0.0402
Loa Loa (eye worm) BEN-1 protein 0.2106 0.5563 1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0037 0.0067
Echinococcus multilocularis axis inhibition protein axin 0.0048 0.0075 0.0075
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.0062 0.0105
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0098 0.0208 0.0326
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0038 0.0048 0.0345
Brugia malayi MH2 domain containing protein 0.0047 0.0071 0.0128
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.0034 0.0062
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0021 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0098 0.0177
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0014 0.0045
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0035 0.0064
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.012 0.0268 0.0481
Brugia malayi 6-phosphofructokinase 0.0126 0.0282 0.0507
Trichomonas vaginalis ABC transporter, putative 0.0025 0.0014 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.017 0.0306
Echinococcus granulosus tubulin alpha 1C chain 0.1523 0.4009 0.6285
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0034 0.0054
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0061 0.011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0028
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0281 0.0506
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Loa Loa (eye worm) PXA domain-containing protein 0.0048 0.0075 0.0135
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0033 0.0035 0.0035
Plasmodium vivax multidomain scavenger receptor, putative 0.0179 0.0425 0.0758
Leishmania major cytochrome p450-like protein 0.0024 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0076 0.0148 0.0267
Echinococcus multilocularis Tubulin beta 2C chain 0.2106 0.5563 0.5563
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0025 0.0014 0.0025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0048 0.0087
Echinococcus multilocularis tubulin alpha 3 chain 0.1523 0.4009 0.4009
Trypanosoma brucei alpha tubulin 0.1523 0.4009 0.7206
Echinococcus granulosus mixed lineage leukemia protein mll 0.0028 0.0021 0.0033
Brugia malayi PAS domain containing protein 0.0226 0.055 0.0989
Echinococcus granulosus tubulin beta 1 chain 0.2106 0.5563 0.8721
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0059 0.0104 0.0186
Plasmodium vivax delta tubulin, putative 0.0508 0.1301 0.2333
Schistosoma mansoni hypothetical protein 0.0943 0.2461 0.3858
Trypanosoma brucei zeta tubulin, putative 0.084 0.2186 0.393
Echinococcus multilocularis lamin dm0 0.0093 0.0196 0.0196
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0061 0.011
Leishmania major beta tubulin 0.2106 0.5563 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0076 0.0148 0.0233
Echinococcus granulosus Smad4 0.0047 0.0071 0.0111
Schistosoma mansoni hypothetical protein 0.0056 0.0097 0.0153
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0037 0.143
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0038 0.0048 0.0345
Echinococcus granulosus mitogen activated protein kinase 0.012 0.0268 0.0419
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0125 0.0281 0.0506
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0043 0.0062 0.0105
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Brugia malayi PXA domain containing protein 0.0048 0.0075 0.0135
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0038 0.0048 0.008
Echinococcus multilocularis dnaJ subfamily B 0.0943 0.2461 0.2461
Brugia malayi tubulin alpha-2 chain 0.1523 0.4009 0.7206
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0105 0.0228 0.041
Plasmodium falciparum multidrug resistance protein 1 0.0025 0.0014 0.0018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0005 0.001
Loa Loa (eye worm) tubulin alpha chain 0.1523 0.4009 0.7206
Brugia malayi MH1 domain containing protein 0.0026 0.0015 0.0028
Echinococcus multilocularis tubulin alpha chain 0.1523 0.4009 0.4009
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0024 0.0012 0.0061
Brugia malayi Nuclear hormone receptor-like 1 0.0076 0.0148 0.0267
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.012 0.0268 0.0481
Trypanosoma brucei beta tubulin 0.2106 0.5563 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0034 0.0034
Entamoeba histolytica recQ family helicase, putative 0.0036 0.0043 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0104 0.0186
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0025 0.0014 0.0018
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0024 0.0012 0.0061
Leishmania major delta tubulin, putative 0.0706 0.183 0.3286
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0024 0.0012 0.0061
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.006 0.0106 0.0191
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0059 0.0104 0.018
Schistosoma mansoni 6-phosphofructokinase 0.0125 0.0281 0.0441
Entamoeba histolytica hypothetical protein 0.0025 0.0014 0.0024
Trypanosoma brucei tubulin delta chain 0.0706 0.183 0.3291
Echinococcus granulosus mothers against decapentaplegic 6 0.0021 0.0002 0.0004
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0084 0.0171 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.001
Onchocerca volvulus 0.0025 0.0014 0.0055
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0025 0.0014 0.0025
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.0012 0.0029
Trichomonas vaginalis tubulin gamma chain, putative 0.0508 0.1301 0.2338
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.001
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.013 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0041 0.0074
Leishmania major phosphatidylinositol 3-kinase, putative 0.0035 0.0041 0.0067
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Toxoplasma gondii isocitrate dehydrogenase 0.0036 0.0044 0.0079
Brugia malayi hypothetical protein 0.0043 0.0061 0.011
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.012 0.0268 0.0481
Giardia lamblia Alpha-tubulin 0.1523 0.4009 0.7204
Echinococcus multilocularis multidrug resistance protein 1 0.0025 0.0014 0.0014
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0038 0.0048 0.008
Loa Loa (eye worm) hypothetical protein 0.0092 0.0191 0.0343
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0104 0.0186
Schistosoma mansoni regulator of G protein signaling 0.0048 0.0075 0.0118
Schistosoma mansoni nuclear receptor 0.0033 0.0034 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0075 0.0135
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0706 0.183 0.3291
Echinococcus granulosus axis inhibition protein axin 0.0048 0.0075 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0076 0.0148 0.0267
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0781 0.1405
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0012 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0076 0.0148 0.0267
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0025 0.0014 0.0025
Trichomonas vaginalis tubulin gamma chain, putative 0.2106 0.5563 1
Entamoeba histolytica hypothetical protein 0.0206 0.0495 0.089
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0033 0.0035 0.0064
Onchocerca volvulus Putative organic anion transporter 0.0099 0.021 0.0986
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.017 0.0306
Loa Loa (eye worm) hypothetical protein 0.0415 0.1054 0.1894
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0036 0.0044 0.0072
Echinococcus granulosus lamin dm0 0.0093 0.0196 0.0307
Loa Loa (eye worm) hypothetical protein 0.0076 0.0148 0.0267
Schistosoma mansoni ap endonuclease 0.0021 0.0004 0.0006
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0087 0.0179 0.0315
Trichomonas vaginalis PIKK family atypical protein kinase 0.0105 0.0228 0.041
Echinococcus multilocularis multidrug resistance protein 1 0.0025 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0099 0.0177
Brugia malayi tailless protein 0.0033 0.0034 0.0062
Echinococcus granulosus tubulin delta chain 0.0508 0.1301 0.2039
Echinococcus multilocularis 0.0024 0.0012 0.0012
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.0145 0.0227
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0097 0.0207 0.0371
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0037 0.006
Echinococcus multilocularis jun protein 0.0284 0.0705 0.0705
Trypanosoma cruzi zeta tubulin, putative 0.084 0.2186 0.393
Loa Loa (eye worm) MH2 domain-containing protein 0.0021 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0765
Schistosoma mansoni regulator of G protein signaling 0.0048 0.0075 0.0118
Echinococcus granulosus tubulin subunit beta 0.2106 0.5563 0.8721
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0077 0.0153 0.0275
Trypanosoma brucei beta tubulin 0.2106 0.5563 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.001
Echinococcus granulosus raf serine:threonine protein kinase 0.005 0.008 0.0125
Echinococcus multilocularis raf serine:threonine protein kinase 0.005 0.008 0.008
Trichomonas vaginalis adenylate cyclase, putative 0.0059 0.0104 0.0186
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0035 0.0041 0.0074
Trypanosoma cruzi fatty acid desaturase, putative 0.0223 0.0541 0.0972
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0024 0.0012 0.0061
Entamoeba histolytica P-glyco protein 6, putative 0.0025 0.0014 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0076 0.0148 0.0267
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0014 0.0022
Onchocerca volvulus 0.0099 0.021 0.0986
Trypanosoma cruzi zeta tubulin, putative 0.084 0.2186 0.393
Echinococcus granulosus TGF beta signal transducer SmadC 0.0047 0.0071 0.0111
Echinococcus multilocularis Tubulin alpha 1 chain 0.1523 0.4009 0.4009
Schistosoma mansoni nuclear hormone receptor 0.0076 0.0148 0.0233
Schistosoma mansoni cpg binding protein 0.0097 0.0205 0.0322
Brugia malayi hypothetical protein 0.0206 0.0495 0.089
Entamoeba histolytica hypothetical protein 0.0048 0.0075 0.0135
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.012 0.0268 0.0475
Leishmania major beta tubulin 0.2106 0.5563 1
Echinococcus multilocularis neuropeptide s receptor 0.107 0.2801 0.2801
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0044 0.0064 0.0114
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0038 0.0048 0.008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0044 0.0044
Echinococcus multilocularis cpg binding protein 0.0102 0.022 0.022
Brugia malayi nuclear receptor NHR-67 0.0033 0.0034 0.0062
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0044 0.0072
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0035 0.0041 0.0067
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0135
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0135
Loa Loa (eye worm) hypothetical protein 0.0043 0.0061 0.011
Loa Loa (eye worm) 6-phosphofructokinase 0.0125 0.0281 0.0506
Brugia malayi Isocitrate dehydrogenase 0.0036 0.0044 0.0079
Leishmania major cytochrome p450-like protein 0.0024 0.0012 0.0014
Schistosoma mansoni Smad4 0.0021 0.0002 0.0004
Trichomonas vaginalis tubulin beta chain, putative 0.1523 0.4009 0.7206
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0037 0.0067
Brugia malayi alpha-tubulin 0.1523 0.4009 0.7206
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0043 0.0062 0.0098
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0024 0.0012 0.0061
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0062 0.0062
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0281 0.0506
Brugia malayi ecdysone receptor 0.0033 0.0034 0.0062
Mycobacterium tuberculosis Probable oxidoreductase 0.0279 0.069 0.5293
Giardia lamblia Gamma tubulin 0.1163 0.3048 0.5476
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.001
Trypanosoma cruzi trypanothione reductase, putative 0.011 0.024 0.0432
Loa Loa (eye worm) hypothetical protein 0.0277 0.0685 0.1231
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0099 0.021 0.021
Trypanosoma brucei beta tubulin 0.2106 0.5563 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0076 0.0148 0.0267
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0023 0.0008 0.0014
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0014 0.0024
Echinococcus multilocularis hypothetical protein 0.1523 0.4009 0.4009
Echinococcus granulosus Tubulin beta 2C chain 0.2106 0.5563 0.8721
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0005 0.001
Brugia malayi Regulator of G protein signaling domain containing protein 0.0048 0.0075 0.0135
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0036 0.0044 0.0079
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0036 0.0044 0.0072
Mycobacterium ulcerans cell division protein FtsZ 0.0508 0.1301 1
Echinococcus granulosus Regulator of G protein signaling 20 0.0048 0.0075 0.0118
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0047 0.0071 0.0111
Trichomonas vaginalis abcb9, putative 0.0025 0.0014 0.0025
Schistosoma mansoni smdr2 0.0025 0.0014 0.0022
Loa Loa (eye worm) RGS-3 protein 0.0048 0.0075 0.0135
Echinococcus multilocularis tubulin, beta 4A class IVa 0.2106 0.5563 0.5563
Schistosoma mansoni lipoxygenase 0.0716 0.1857 0.2911
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.005 0.008 0.0143
Echinococcus granulosus Tubulin beta 2C chain 0.2106 0.5563 0.8721
Echinococcus granulosus jun protein 0.0284 0.0705 0.1106
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0184 0.0184
Echinococcus granulosus agrin 0.0067 0.0126 0.0198
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0022 0.0006 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0024 0.0012 0.0061
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0025 0.0014 0.0025
Loa Loa (eye worm) steroid hormone receptor 0.0076 0.0148 0.0267
Plasmodium falciparum thioredoxin reductase 0.011 0.024 0.0425
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1523 0.4009 0.7206
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0041 0.0074
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0281 0.0506
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.0043 0.0071
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0038 0.0048 0.2109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.017 0.0306
Schistosoma mansoni lamin 0.0093 0.0196 0.0307
Echinococcus multilocularis thioredoxin glutathione reductase 0.011 0.024 0.024
Loa Loa (eye worm) histone methyltransferase 0.0034 0.0037 0.0066
Toxoplasma gondii alpha tubulin TUBA1 0.1523 0.4009 0.7206
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0005 0.001
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0059 0.0104 0.0104
Schistosoma mansoni z-protein (S1r protein) 0.0048 0.0075 0.0118
Echinococcus granulosus Niemann Pick C1 protein 0.0227 0.0552 0.0865
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0025 0.0013 0.002
Trypanosoma cruzi tubulin delta chain 0.0706 0.183 0.3291
Trypanosoma brucei fatty acid desaturase, putative 0.0223 0.0541 0.0972
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0005 0.001
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0284 0.0705 0.0705
Loa Loa (eye worm) MH2 domain-containing protein 0.0683 0.1768 0.3178
Loa Loa (eye worm) MH1 domain-containing protein 0.0021 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0067 0.0126 0.0227
Echinococcus granulosus regulator of G protein signaling 7 0.0048 0.0075 0.0118
Treponema pallidum NADH oxidase 0.0038 0.0048 0.0345
Schistosoma mansoni nuclear receptor 0.0033 0.0034 0.0054
Loa Loa (eye worm) hypothetical protein 0.0043 0.0061 0.011
Echinococcus multilocularis beta adrenergic receptor kinase 0.0049 0.0078 0.0078
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0125 0.0281 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0062 0.0112
Schistosoma mansoni hypothetical protein 0.0968 0.2528 0.3964
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0105 0.0228 0.041
Echinococcus multilocularis tubulin epsilon chain 0.1163 0.3047 0.3047
Schistosoma mansoni Smad4 0.0047 0.0071 0.0111
Brugia malayi cytoplasmic intermediate filament protein 0.005 0.008 0.0144
Echinococcus multilocularis lamin 0.0093 0.0196 0.0196
Onchocerca volvulus 0.081 0.2106 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0025 0.0014 0.0022
Trichomonas vaginalis tubulin epsilon chain, putative 0.2106 0.5563 1
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0028 0.0022 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0005 0.001
Brugia malayi regulator of G-protein signaling rgs-7 0.0048 0.0075 0.0135
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0043 0.0061 0.011
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0033 0.0035 0.0055
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0011 0.0016
Trypanosoma brucei trypanothione reductase 0.011 0.024 0.0432
Plasmodium vivax stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative 0.0205 0.0493 0.0879
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0076 0.0148 0.0148
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0038 0.0048 0.0076
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0077 0.0153 0.024
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0539 0.1385 0.249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0115 0.0206
Schistosoma mansoni hypothetical protein 0.0094 0.0197 0.0309
Brugia malayi Doublecortin family protein 0.0179 0.0425 0.0765
Brugia malayi regulator of G-protein signaling egl-10 0.0048 0.0075 0.0135
Plasmodium vivax tubulin alpha chain, putative 0.1523 0.4009 0.7204
Brugia malayi hypothetical protein 0.0117 0.0259 0.0466
Giardia lamblia Alpha-tubulin 0.1523 0.4009 0.7204
Loa Loa (eye worm) nuclear factor I 0.0026 0.0015 0.0028
Toxoplasma gondii cytochrome p450 superfamily protein 0.0024 0.0012 0.0021
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0037 0.0067
Echinococcus multilocularis regulator of G protein signaling 7 0.0048 0.0075 0.0075
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0131 0.0978
Trypanosoma brucei zeta tubulin 0.084 0.2186 0.393
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0024 0.0012 0.0061
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.012 0.0268 0.0481
Brugia malayi hypothetical protein 0.0033 0.0034 0.0062
Brugia malayi phosphofructokinase 0.0125 0.0281 0.0506
Brugia malayi Thioredoxin reductase 0.011 0.024 0.0432
Chlamydia trachomatis endonuclease IV 0.0087 0.0179 1
Echinococcus multilocularis tubulin alpha 0.1131 0.2962 0.2962
Trichomonas vaginalis PIKK family atypical protein kinase 0.0105 0.0228 0.041
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0036 0.0044 0.0069
Onchocerca volvulus 0.0099 0.021 0.0986
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0781 0.1405
Loa Loa (eye worm) hypothetical protein 0.0076 0.0148 0.0267
Loa Loa (eye worm) agrin synaptic family protein 0.0067 0.0126 0.0227
Giardia lamblia NADH oxidase lateral transfer candidate 0.0038 0.0048 0.008
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0014 0.0076
Loa Loa (eye worm) hypothetical protein 0.0099 0.021 0.0377
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0104 0.0224 0.0224
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0014 0.0076
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0035 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0104 0.0186
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0268 0.0481
Trypanosoma cruzi epsilon tubulin, putative 0.1163 0.3047 0.5477
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.0048 0.008
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0025 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0006 0.0011
Plasmodium falciparum tubulin delta chain, putative 0.0508 0.1301 0.2333
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0024 0.0012 0.0061
Onchocerca volvulus 0.0067 0.0126 0.059
Brugia malayi isocitrate dehydrogenase 0.0036 0.0044 0.0079
Trichomonas vaginalis tubulin gamma chain, putative 0.1163 0.3048 0.5479
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0004 0.0007
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0044 0.0079
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0024 0.0012 0.0061
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.0034 0.0062
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0131 0.0978
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0034 0.0037 0.0037
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0038 0.0048 0.008
Entamoeba histolytica P-glycoprotein-2, putative 0.0025 0.0014 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0076 0.0148 0.0148
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0043 0.0062 0.0098
Plasmodium falciparum tubulin gamma chain 0.1163 0.3048 0.5476
Schistosoma mansoni tubulin subunit gamma 0.1163 0.3048 0.4779
Echinococcus multilocularis tubulin gamma 1 chain 0.1163 0.3048 0.3048
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0284 0.0705 0.1106
Schistosoma mansoni hypothetical protein 0.0024 0.0012 0.0018
Echinococcus granulosus tubulin alpha 3 chain 0.1523 0.4009 0.6285
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0035 0.0041 0.0041
Echinococcus multilocularis Niemann Pick C1 protein 0.0227 0.0552 0.0552
Plasmodium falciparum alpha tubulin 2 0.1523 0.4009 0.7204
Onchocerca volvulus 0.0223 0.0541 0.2559
Schistosoma mansoni tubulin subunit beta 0.2106 0.5563 0.8721
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0059 0.0104 0.0186
Schistosoma mansoni smad 0.0047 0.0071 0.0111
Echinococcus granulosus mothers against decapentaplegic 5 0.0047 0.0071 0.0111
Echinococcus multilocularis tubulin alpha 1C chain 0.1523 0.4009 0.4009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0041 0.0074
Treponema pallidum fructose-bisphosphate aldolase 0.0313 0.0781 0.5995
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0021 0.0033
Brugia malayi nuclear receptor RXR 0.0033 0.0034 0.0062
Schistosoma mansoni tubulin subunit alpha 0.1523 0.4009 0.6285
Leishmania major alpha tubulin 0.1523 0.4009 0.7204
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0024 0.0012 0.0061
Mycobacterium tuberculosis Probable reductase 0.0251 0.0616 0.4718
Echinococcus multilocularis expressed protein 0.0067 0.0126 0.0126
Trichomonas vaginalis tubulin epsilon chain, putative 0.1523 0.4009 0.7206
Loa Loa (eye worm) raf kinase 0.005 0.008 0.0143
Loa Loa (eye worm) alpha-tubulin isotype 2 0.1016 0.2655 0.4772
Echinococcus granulosus survival motor neuron protein 1 0.0277 0.0684 0.1073
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0135
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0034 0.0034
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0025 0.0014 0.0025
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0153 0.0275
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0034 0.0054
Brugia malayi Tubulin beta-1 chain 0.2106 0.5563 1
Echinococcus granulosus transcription factor Dp 1 0.0045 0.0066 0.0104
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.012 0.0268 0.0481
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0048 0.0075 0.0118
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Loa Loa (eye worm) hypothetical protein 0.0045 0.0067 0.012
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0125 0.0281 0.2141
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0104 0.0224 0.0351
Echinococcus granulosus FTZ F1 alpha 0.0076 0.0148 0.0233
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0034 0.0034
Trypanosoma brucei alpha tubulin, putative 0.0623 0.1608 0.2891
Trichomonas vaginalis tubulin beta chain, putative 0.1523 0.4009 0.7206
Echinococcus granulosus beta tubulin 0.2106 0.5563 0.8721
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0024 0.0012 0.0061
Trypanosoma brucei PAB1-binding protein , putative 0.0117 0.0259 0.0466
Echinococcus granulosus RUN 0.0179 0.0425 0.0667
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0076 0.0148 0.0233
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0076 0.0148 0.0233
Loa Loa (eye worm) alpha-tubulin 0.1523 0.4009 0.7206
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0104 0.0224 0.0351
Plasmodium vivax tubulin epsilon chain, putative 0.1163 0.3047 0.5474
Schistosoma mansoni organic anion transporter 0.0099 0.021 0.0329
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0025 0.0014 0.0025
Brugia malayi Smad1 0.0047 0.0071 0.0128
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0076 0.0148 0.0233
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0048 0.0087
Echinococcus multilocularis CREB binding protein 0.0036 0.0042 0.0042
Entamoeba histolytica tubulin family protein 0.2106 0.5563 1
Brugia malayi secreted modular calcium-binding protein 1 0.0067 0.0126 0.0227
Plasmodium falciparum tubulin beta chain 0.2106 0.5563 1
Trichomonas vaginalis helicase, putative 0.0022 0.0005 0.001
Schistosoma mansoni polycystin 1-related 0.0179 0.0425 0.0667
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0099 0.021 0.0377
Schistosoma mansoni Smad4 0.0021 0.0002 0.0004
Brugia malayi Cytochrome P450 family protein 0.0074 0.0144 0.0259
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.0034 0.0054
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0038 0.0048 0.0345
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0025 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0054
Trichomonas vaginalis DNA helicase recq, putative 0.0036 0.0043 0.0078
Brugia malayi MH1 domain containing protein 0.0047 0.0071 0.0128
Echinococcus granulosus mothers against decapentaplegic 2 0.0021 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0014
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0025 0.0014 0.0025
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0153 0.0354 0.2681
Trichomonas vaginalis PIKK family atypical protein kinase 0.0105 0.0228 0.041
Onchocerca volvulus Protein ultraspiracle homolog 0.0076 0.0148 0.0694
Onchocerca volvulus 0.0223 0.0541 0.2559
Toxoplasma gondii isocitrate dehydrogenase 0.0036 0.0044 0.0079
Toxoplasma gondii endonuclease IV APN 0.0087 0.0179 0.0321
Loa Loa (eye worm) tubulin beta chain 0.0508 0.1301 0.2338
Loa Loa (eye worm) hypothetical protein 0.0043 0.0061 0.011
Plasmodium falciparum tubulin epsilon chain, putative 0.1163 0.3047 0.5474
Toxoplasma gondii transporter, major facilitator family protein 0.0099 0.021 0.0377
Onchocerca volvulus 0.0099 0.021 0.0986
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0062
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0043 0.0061 0.0096
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0024 0.0012 0.0061
Loa Loa (eye worm) RecQ helicase 0.0047 0.0073 0.0132
Onchocerca volvulus 0.0179 0.0425 0.2011
Echinococcus granulosus follistatin 0.0067 0.0126 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.017 0.0306
Entamoeba histolytica tubulin gamma chain 0.1163 0.3048 0.5479
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0011 0.0011
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0035 0.0041 0.0074
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0073 0.0132
Brugia malayi hypothetical protein 0.0179 0.0425 0.0765
Brugia malayi Tubulin beta chain 0.0623 0.1608 0.2891
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.005 0.008 0.0144
Brugia malayi nuclear receptor RXR 0.0043 0.0061 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0075 0.0135
Loa Loa (eye worm) hypothetical protein 0.0043 0.0062 0.0112
Entamoeba histolytica P-glycoprotein-1 0.0025 0.0014 0.0025
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0104 0.0224 0.0224
Onchocerca volvulus 0.0097 0.0205 0.0965
Trichomonas vaginalis tubulin alpha chain, putative 0.2106 0.5563 1

Activities

Activity type Activity value Assay description Source Reference
Drug uptake (ADMET) = 0.47 uM Drug uptake in C57BL/6 mouse liver at 10 mg/kg, po after 6 hrs ChEMBL. 21924609
Drug uptake (ADMET) = 0.9 uM Drug uptake in C57BL/6 mouse liver at 30 mg/kg, po after 3 hrs ChEMBL. 21924609
IC50 (binding) = 56 nM Inhibition of rat SCD by rat microsomal assay ChEMBL. 21924609
IC50 (binding) = 694 nM Inhibition of SCD in rat hepatocytes assessed as conversion of [14C]-stearic acid to [14C]-oleic acid preincubated for 15 mins measured after 1 hrs by scintillation counting ChEMBL. 21924609
IC50 (binding) = 6308 nM Inhibition of SCD in human HepG2 cells assessed as conversion of [1-(14)C]-stearic acid to (14)C-oleic acid ChEMBL. 21924609

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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