Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0028 | 0.0253 | 0.0226 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0053 | 0.0537 | 0.186 |
Echinococcus multilocularis | ferritin | 0.001 | 0.0056 | 0.0028 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0053 | 0.0537 | 0.49 |
Trichomonas vaginalis | ferritin, putative | 0.001 | 0.0056 | 0.0665 |
Schistosoma mansoni | nuclear hormone receptor | 0.0013 | 0.0093 | 0.0115 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0053 | 0.0537 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0537 | 0.49 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0305 | 0.1058 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0013 | 0.0093 | 0.0324 |
Echinococcus granulosus | tar DNA binding protein | 0.0268 | 0.2887 | 0.5045 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0028 | 0.0253 | 0.0878 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0013 | 0.0093 | 0.0115 |
Echinococcus multilocularis | tar DNA binding protein | 0.0268 | 0.2887 | 0.2867 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.0624 | 0.1051 |
Schistosoma mansoni | nuclear hormone receptor | 0.0013 | 0.0093 | 0.0115 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0028 | 0.0253 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0042 | 0.0409 | 0.0382 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0028 | 0.0253 | 0.0878 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0028 | 0.0253 | 0.0878 |
Brugia malayi | conserved hypotetical protein | 0.0013 | 0.0093 | 0.0324 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0053 | 0.0537 | 0.49 |
Brugia malayi | tailless protein | 0.0013 | 0.0093 | 0.0324 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0089 | 0.0926 | 0.3208 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0015 | 0.0111 | 0.0083 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0013 | 0.0093 | 0.0065 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0028 | 0.0253 | 0.0878 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0163 | 1 |
Echinococcus multilocularis | expressed protein | 0.001 | 0.0056 | 0.0028 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0952 | 0.0926 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0028 | 0.0253 | 0.0878 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0028 | 0.0253 | 0.0226 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.004 | 0.0021 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0028 | 0.0253 | 0.1044 |
Schistosoma mansoni | tar DNA-binding protein | 0.0268 | 0.2887 | 0.5045 |
Brugia malayi | nuclear receptor NHR-88 | 0.0028 | 0.0253 | 0.0878 |
Brugia malayi | Protein kinase domain containing protein | 0.0089 | 0.0926 | 0.3208 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.004 | 0.0021 |
Schistosoma mansoni | ferritin | 0.001 | 0.0056 | 0.0049 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0028 | 0.0253 | 0.0226 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.1261 | 0.4368 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.004 | 0.0021 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0028 | 0.0253 | 0.0397 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.004 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0253 | 0.0878 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0281 | 0.0446 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.1072 | 0.3713 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0305 | 0.0278 |
Loa Loa (eye worm) | DR-78 | 0.0013 | 0.0093 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0253 | 0.0878 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0028 | 0.0253 | 0.0878 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.004 | 0.0138 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.004 | 0.0138 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0624 | 0.0597 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0028 | 0.0253 | 0.0397 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.004 | 0.0012 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0624 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 0.0537 | 0.0898 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0952 | 0.0926 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0013 | 0.0093 | 0.0115 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.0743 | 0.76 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.0624 | 1 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Trypanosoma brucei | protein kinase, putative | 0.0053 | 0.0537 | 0.49 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0028 | 0.0253 | 0.0878 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.004 | 0.0138 |
Schistosoma mansoni | nuclear hormone receptor | 0.0028 | 0.0253 | 0.0397 |
Echinococcus multilocularis | geminin | 0.0524 | 0.5695 | 0.5682 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0028 | 0.0253 | 0.0397 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.0952 | 0.3298 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0163 | 0.2749 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0028 | 0.0253 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0111 | 0.0383 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.0743 | 0.76 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.1261 | 0.4368 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1575 | 0.5455 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0028 | 0.0253 | 0.0878 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0028 | 0.0253 | 0.0878 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0163 | 0.0565 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0624 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0042 | 0.0409 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0028 | 0.0253 | 0.0226 |
Brugia malayi | nuclear receptor NHR-88 | 0.0013 | 0.0093 | 0.0324 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0013 | 0.0093 | 0.0065 |
Schistosoma mansoni | zinc finger protein | 0.0013 | 0.0093 | 0.0115 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0952 | 0.163 |
Onchocerca volvulus | 0.0153 | 0.1625 | 1 | |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.004 | 0.0021 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0013 | 0.0093 | 0.0324 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0053 | 0.0537 | 0.49 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.0624 | 0.6033 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0053 | 0.0537 | 0.8123 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0624 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0013 | 0.0093 | 0.0065 |
Brugia malayi | RNA binding protein | 0.0268 | 0.2887 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0028 | 0.0253 | 0.0878 |
Schistosoma mansoni | nuclear receptor | 0.0013 | 0.0093 | 0.0115 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0028 | 0.0253 | 0.0226 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0047 | 0.0034 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0305 | 0.0489 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0717 | 0.1216 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0028 | 0.0253 | 0.0878 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0028 | 0.0253 | 0.1044 |
Brugia malayi | TAR-binding protein | 0.0268 | 0.2887 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0013 | 0.0093 | 0.0324 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0405 | 0.4398 | 0.4382 |
Loa Loa (eye worm) | RNA binding protein | 0.0268 | 0.2887 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0028 | 0.0253 | 0.0397 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0028 | 0.0253 | 0.0397 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0624 | 0.1051 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0028 | 0.0253 | 0.1044 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0952 | 0.163 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0028 | 0.0253 | 0.0397 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0013 | 0.0093 | 0.0065 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0163 | 0.0238 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0163 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0268 | 0.2887 | 0.5045 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.004 | 0.0021 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0163 | 0.0238 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.004 | 0.0138 |
Schistosoma mansoni | ferritin light chain | 0.001 | 0.0056 | 0.0049 |
Echinococcus multilocularis | muscleblind protein | 0.0148 | 0.1575 | 0.1551 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0305 | 0.0489 |
Entamoeba histolytica | protein kinase, putative | 0.0089 | 0.0926 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0013 | 0.0093 | 0.0324 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0613 | 0.1032 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0072 | 0.0743 | 0.1262 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0028 | 0.0253 | 0.0878 |
Schistosoma mansoni | ferritin | 0.001 | 0.0056 | 0.0049 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0072 | 0.0743 | 0.1262 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.004 | 0.0138 |
Brugia malayi | Smad1 | 0.0008 | 0.004 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0952 | 0.163 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0281 | 0.0446 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0072 | 0.0743 | 0.2574 |
Schistosoma mansoni | tar DNA-binding protein | 0.0268 | 0.2887 | 0.5045 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0268 | 0.2887 | 1 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.001 | 0.0056 | 0.5 |
Schistosoma mansoni | ferritin | 0.001 | 0.0056 | 0.0049 |
Loa Loa (eye worm) | TAR-binding protein | 0.0268 | 0.2887 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0268 | 0.2887 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0524 | 0.5695 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0537 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1575 | 0.5455 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0542 | 0.8234 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0013 | 0.0093 | 0.0065 |
Schistosoma mansoni | hypothetical protein | 0.0405 | 0.4398 | 0.7712 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0305 | 0.0489 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0089 | 0.0926 | 0.1585 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.0952 | 0.3298 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0015 | 0.0111 | 0.0145 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0053 | 0.0537 | 0.0898 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0015 | 0.0111 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0253 | 0.0878 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0028 | 0.0253 | 0.0878 |
Schistosoma mansoni | smad | 0.0008 | 0.004 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0305 | 0.0489 |
Brugia malayi | ecdysone receptor | 0.0013 | 0.0093 | 0.0324 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0537 | 0.49 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0015 | 0.0111 | 0.0145 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0072 | 0.0743 | 0.76 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0072 | 0.0743 | 0.0717 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0028 | 0.0253 | 0.0878 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0028 | 0.0253 | 0.0397 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0028 | 0.0253 | 0.0397 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0624 | 0.1051 |
Echinococcus granulosus | geminin | 0.0524 | 0.5695 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0028 | 0.0253 | 0.0397 |
Echinococcus multilocularis | dual specificity | 0.0089 | 0.0926 | 0.0901 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0013 | 0.0093 | 0.0324 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.1072 | 0.3713 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0263 | 0.0911 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0046 | 0.0159 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.1261 | 0.4368 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0053 | 0.0537 | 0.49 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0305 | 0.1058 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.004 | 0.0012 |
Schistosoma mansoni | ferritin | 0.001 | 0.0056 | 0.0049 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0163 | 0.1892 |
Brugia malayi | nuclear receptor RXR | 0.0013 | 0.0093 | 0.0324 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0028 | 0.0253 | 0.0397 |
Brugia malayi | MAP kinase sur-1 | 0.0053 | 0.0537 | 0.186 |
Echinococcus granulosus | smad | 0.0008 | 0.004 | 0.0021 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0047 | 0.0019 |
Entamoeba histolytica | protein kinase, putative | 0.0089 | 0.0926 | 1 |
Schistosoma mansoni | apoferritin-2 | 0.001 | 0.0056 | 0.0049 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0028 | 0.0253 | 0.0878 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0163 | 0.1892 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0028 | 0.0253 | 0.0397 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0028 | 0.0253 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0111 | 0.0383 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0305 | 0.0489 |
Schistosoma mansoni | thyroid hormone receptor | 0.0028 | 0.0253 | 0.0397 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0028 | 0.0253 | 0.0878 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0089 | 0.0926 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0013 | 0.0093 | 0.0115 |
Brugia malayi | nuclear receptor RXR | 0.0015 | 0.0111 | 0.0383 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.1072 | 0.3713 |
Onchocerca volvulus | 0.0028 | 0.0263 | 0.1106 | |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0013 | 0.0093 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0111 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0253 | 0.0878 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.004 | 0.0021 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.004 | 0.0138 |
Brugia malayi | hypothetical protein | 0.0153 | 0.1625 | 0.563 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0089 | 0.0926 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0089 | 0.0926 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Schistosoma mansoni | thyroid hormone receptor | 0.0028 | 0.0253 | 0.0397 |
Echinococcus granulosus | muscleblind protein | 0.0148 | 0.1575 | 0.2729 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0537 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0028 | 0.0253 | 0.0397 |
Schistosoma mansoni | tar DNA-binding protein | 0.0268 | 0.2887 | 0.5045 |
Schistosoma mansoni | ferritin light chain | 0.001 | 0.0056 | 0.0049 |
Brugia malayi | nuclear receptor NHR-67 | 0.0013 | 0.0093 | 0.0324 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0163 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0028 | 0.0253 | 0.0226 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0305 | 0.0278 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0263 | 0.0911 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0537 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0253 | 0.0878 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0916 | 0.3173 |
Brugia malayi | hypothetical protein | 0.0015 | 0.0111 | 0.0383 |
Echinococcus granulosus | ferritin | 0.001 | 0.0056 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Brugia malayi | Muscleblind-like protein | 0.0148 | 0.1575 | 0.5455 |
Echinococcus multilocularis | smad | 0.0008 | 0.004 | 0.0012 |
Onchocerca volvulus | 0.0028 | 0.0253 | 0.1044 | |
Schistosoma mansoni | apoferritin-2 | 0.001 | 0.0056 | 0.0049 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0537 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0952 | 0.163 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.004 | 0.0012 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0028 | 0.0253 | 0.0878 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0163 | 0.2749 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0111 | 0.0383 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0028 | 0.0253 | 0.0878 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0053 | 0.0537 | 0.49 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0072 | 0.0743 | 0.76 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0053 | 0.0537 | 0.0898 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0028 | 0.0253 | 0.0878 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0163 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0111 | 0.0383 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0047 | 0.0164 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0163 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0028 | 0.0253 | 0.0397 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0163 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.1625 | 0.563 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0013 | 0.0093 | 0.0115 |
Schistosoma mansoni | nuclear receptor | 0.0013 | 0.0093 | 0.0115 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0028 | 0.0253 | 0.0878 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0028 | 0.0253 | 0.0397 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0072 | 0.0743 | 0.2574 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0305 | 0.0489 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0013 | 0.0093 | 0.0324 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0305 | 0.1058 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0305 | 0.0278 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0013 | 0.0093 | 0.0324 |
Echinococcus granulosus | FTZ F1 alpha | 0.0028 | 0.0253 | 0.0397 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0028 | 0.0253 | 0.0878 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0263 | 0.0414 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0013 | 0.0093 | 0.0115 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0013 | 0.0093 | 0.0324 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.0717 | 0.2484 |
Echinococcus granulosus | expressed protein | 0.001 | 0.0056 | 0.0049 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0163 | 0.0565 |
Brugia malayi | nuclear hormone receptor | 0.0013 | 0.0093 | 0.0324 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.0743 | 0.76 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.004 | 0.0021 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0053 | 0.0537 | 0.051 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0013 | 0.0093 | 0.0115 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0013 | 0.0093 | 0.0115 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0281 | 0.0446 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0305 | 0.1058 |
Brugia malayi | ecdysteroid receptor | 0.0028 | 0.0253 | 0.0878 |
Schistosoma mansoni | hypothetical protein | 0.0524 | 0.5695 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0405 | 0.4398 | 0.7712 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0015 | 0.0111 | 0.0145 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0028 | 0.0253 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0253 | 0.0878 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0053 | 0.0537 | 0.051 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0028 | 0.0253 | 0.0226 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0015 | 0.0111 | 0.0383 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0013 | 0.0093 | 0.0115 |
Brugia malayi | hypothetical protein | 0.0015 | 0.0111 | 0.0383 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0028 | 0.0253 | 0.0878 |
Brugia malayi | nuclear hormone receptor | 0.0028 | 0.0253 | 0.0878 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0089 | 0.0926 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0268 | 0.2887 | 0.5045 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0028 | 0.0253 | 0.0878 |
Echinococcus granulosus | dual specificity | 0.0089 | 0.0926 | 0.1585 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0624 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0717 | 0.2484 |
Brugia malayi | steroid hormone receptor | 0.0028 | 0.0253 | 0.0878 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0028 | 0.0253 | 0.0878 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0028 | 0.0253 | 0.0397 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0148 | 0.1575 | 0.1551 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0015 | 0.0111 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0253 | 0.0878 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0013 | 0.0093 | 0.0065 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0281 | 0.0253 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0305 | 0.0489 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0253 | 0.0878 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1072 | 0.3713 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0916 | 0.3173 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0013 | 0.0093 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0952 | 0.163 |
Entamoeba histolytica | hypothetical protein | 0.0089 | 0.0926 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0093 | 0.0324 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.004 | 0.0021 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0089 | 0.0926 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0028 | 0.0253 | 0.0226 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.32 uM | Antimicrobial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 harboring pFCA-lux AB gene measured under aerobic condition after 8 days by luminescence analysis | ChEMBL. | 22148391 |
MIC (functional) | > 32 uM | Antimicrobial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 harboring pFCA-lux AB gene measured under anaerobic condition after 11 days by luminescence analysis | ChEMBL. | 22148391 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.