Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.066 | 0.0538 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.0751 | 0.0282 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.058 | 0.0764 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0694 | 0.0839 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0073 | 0.1937 | 0.1875 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0034 | 0.0751 | 0.6028 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.066 | 0.0589 |
Leishmania major | protein kinase, putative | 0.0013 | 0.0076 | 0.0492 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0781 | 0.1057 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.1571 | 0.1461 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.1543 | 1 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1078 | 0.1476 |
Schistosoma mansoni | single-minded | 0.0048 | 0.1174 | 0.1059 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.1153 | 0.1038 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0615 | 0.3983 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0431 | 0.0545 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1543 | 1 |
Loa Loa (eye worm) | ICD-1 protein | 0.0034 | 0.0751 | 0.0994 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0615 | 0.0492 |
Echinococcus multilocularis | geminin | 0.0335 | 1 | 1 |
Onchocerca volvulus | 0.003 | 0.0615 | 0.079 | |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.066 | 0.0589 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0045 | 0.1061 | 0.6879 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.005 | 0.1245 | 0.8071 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0045 | 0.1061 | 0.8524 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0036 | 0.0789 | 0.0718 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0045 | 0.1061 | 0.8524 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0045 | 0.107 | 0.1466 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1078 | 0.0961 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.1061 | 0.1468 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.066 | 0.0589 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0076 | 0.0026 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0045 | 0.1061 | 0.0945 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0107 | 0.3001 | 0.291 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.066 | 0.0789 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0013 | 0.0076 | 0.0026 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0107 | 0.3001 | 0.2947 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0014 | 0.0129 | 0.0053 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0014 | 0.0133 | 0.0004 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0033 | 0.0709 | 0.0862 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.1331 | 0.1265 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.015 | 0.1204 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0045 | 0.1061 | 0.1624 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0014 | 0.0129 | 0.0053 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.071 | 0.0954 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0709 | 0.0953 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0032 | 0.0685 | 0.5503 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1078 | 0.1009 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.1331 | 0.1849 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.066 | 0.0538 |
Echinococcus granulosus | transcription factor btf3 | 0.0034 | 0.0751 | 0.068 |
Brugia malayi | hypothetical protein | 0.0233 | 0.6862 | 1 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0033 | 0.071 | 0.4602 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0561 | 0.0715 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1543 | 0.1432 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0431 | 0.0545 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0431 | 0.0545 |
Brugia malayi | hypothetical protein | 0.0162 | 0.467 | 0.6744 |
Brugia malayi | Death domain containing protein | 0.0014 | 0.0129 | 0.000000094094 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0388 | 0.0314 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0431 | 0.0545 |
Trichomonas vaginalis | rotamase, putative | 0.0032 | 0.0685 | 0.0918 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.1543 | 0.1478 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.066 | 0.0589 |
Brugia malayi | PAS domain containing protein | 0.0048 | 0.1174 | 0.1553 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1543 | 0.1432 |
Onchocerca volvulus | Netrin receptor homolog | 0.0014 | 0.0129 | 0.0078 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.005 | 0.1245 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0562 | 0.049 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0045 | 0.1061 | 0.1452 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1245 | 0.1723 |
Echinococcus granulosus | lamin | 0.0053 | 0.1331 | 0.1265 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0129 | 0.0078 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0781 | 0.1057 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.2757 | 0.3902 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0014 | 0.0129 | 0.0053 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1078 | 0.1009 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.1061 | 0.1468 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.2757 | 0.395 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0206 | 0.6022 | 0.8761 |
Brugia malayi | hypoxia-induced factor 1 | 0.0149 | 0.4284 | 0.6171 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.467 | 0.6769 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.3001 | 0.291 |
Leishmania major | basic transcription factor 3a, putative | 0.0034 | 0.0751 | 0.4865 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.1245 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.015 | 0.0134 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.1543 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0781 | 0.1057 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.1331 | 0.1849 |
Trichomonas vaginalis | set domain proteins, putative | 0.0234 | 0.6894 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0709 | 0.0953 |
Brugia malayi | Cytochrome P450 family protein | 0.0045 | 0.107 | 0.1398 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0076 | 0.0492 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.0482 | 0.0409 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0045 | 0.1061 | 0.6879 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0751 | 0.1013 |
Brugia malayi | hypothetical protein | 0.0107 | 0.3001 | 0.4265 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.066 | 0.0538 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0073 | 0.1937 | 0.1875 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.005 | 0.1245 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0015 | 0.015 | 0.0031 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0076 | 0.0026 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.3001 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1543 | 1 |
Brugia malayi | Uncoordinated protein 44 | 0.0014 | 0.0129 | 0.000000094094 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.015 | 0.1204 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0611 | 0.0539 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0076 | 0.0026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.071 | 0.0954 |
Brugia malayi | Pre-SET motif family protein | 0.0206 | 0.6022 | 0.8751 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0013 | 0.0076 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.1153 | 0.1038 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0045 | 0.1061 | 0.8524 |
Onchocerca volvulus | 0.0047 | 0.1153 | 0.1579 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1078 | 0.1009 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0509 | 0.066 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0561 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0233 | 0.6862 | 1 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0014 | 0.0129 | 0.0053 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0233 | 0.6862 | 0.6838 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0615 | 0.0543 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0034 | 0.0751 | 0.6028 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.3001 | 1 |
Echinococcus granulosus | single minded 2 | 0.0036 | 0.0789 | 0.0718 |
Leishmania major | hypothetical protein, conserved | 0.005 | 0.1245 | 0.8071 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0015 | 0.015 | 0.0109 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0107 | 0.3001 | 0.2947 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.071 | 0.0954 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0018 | 0.026 | 0.2085 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.1786 | 0.2462 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0015 | 0.015 | 0.0021 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.071 | 0.0954 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.015 | 0.0972 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.1331 | 0.1785 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0076 | 0.0026 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.0685 | 0.5503 |
Onchocerca volvulus | 0.0053 | 0.1331 | 0.184 | |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0035 | 0.0782 | 0.5068 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0034 | 0.0751 | 0.6028 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1078 | 0.0961 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0034 | 0.0751 | 0.2157 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0561 | 0.0642 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0014 | 0.0129 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0452 | 0.0554 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0029 | 0.0569 | 0.0654 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0149 | 0.4284 | 0.6201 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0509 | 0.066 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.2837 | 0.2743 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0045 | 0.1061 | 0.8524 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0015 | 0.015 | 0.0075 |
Schistosoma mansoni | lamin | 0.0053 | 0.1331 | 0.1218 |
Echinococcus multilocularis | musashi | 0.0053 | 0.1331 | 0.1265 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.1061 | 0.1468 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.1543 | 0.1478 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.2757 | 0.3902 |
Brugia malayi | beta-NAC-like protein | 0.0034 | 0.0751 | 0.0923 |
Mycobacterium leprae | Possible regulatory protein | 0.0013 | 0.0076 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.015 | 0.0134 |
Onchocerca volvulus | 0.0053 | 0.1331 | 0.184 | |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0045 | 0.1061 | 0.0993 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1078 | 0.1409 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0611 | 0.0539 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.015 | 0.0134 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0076 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0452 | 0.0554 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0615 | 0.0543 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0045 | 0.1061 | 0.1385 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0015 | 0.015 | 0.0972 |
Echinococcus granulosus | death domain containing protein | 0.0014 | 0.0129 | 0.0053 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0781 | 0.1057 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0615 | 0.0794 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0045 | 0.1061 | 0.0993 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.071 | 0.0954 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0388 | 0.0314 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.1543 | 1 |
Echinococcus multilocularis | expressed protein | 0.0033 | 0.0709 | 0.0638 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0751 | 0.1013 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.1374 | 0.8904 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0133 | 0.0083 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 1 | 1 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0048 | 0.1174 | 0.1059 |
Schistosoma mansoni | transcription factor btf3 | 0.0034 | 0.0751 | 0.063 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0615 | 0.0492 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0615 | 0.0721 |
Brugia malayi | hypothetical protein | 0.005 | 0.1245 | 0.1658 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.1245 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.1331 | 0.1849 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0045 | 0.1061 | 0.1624 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0509 | 0.066 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0014 | 0.0129 | 0.000000064186 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0429 | 0.0543 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1786 | 0.252 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1078 | 0.1009 |
Brugia malayi | bHLH-PAS transcription factor | 0.0036 | 0.0789 | 0.098 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0021 | 0.0339 | 0.2719 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.0685 | 0.5503 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0035 | 0.0782 | 0.628 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.066 | 0.0789 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0611 | 0.0488 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0501 | 0.0649 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0615 | 0.0492 |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.1331 | 0.1265 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0032 | 0.0685 | 0.4442 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.0569 | 0.0727 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.015 | 0.1204 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.015 | 0.0134 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.066 | 0.0861 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0709 | 0.0933 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1078 | 0.0961 |
Toxoplasma gondii | NAC domain-containing protein | 0.0034 | 0.0751 | 0.4865 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.2757 | 0.395 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.066 | 0.0538 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0015 | 0.015 | 0.1204 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.066 | 0.0861 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0611 | 0.0488 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.1245 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.3001 | 1 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.1331 | 0.1785 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0615 | 0.0492 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.1153 | 0.1521 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.1786 | 0.1679 |
Echinococcus multilocularis | lamin | 0.0053 | 0.1331 | 0.1265 |
Schistosoma mansoni | rotamase | 0.0033 | 0.0709 | 0.0588 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0781 | 0.1057 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0751 | 0.1013 |
Echinococcus granulosus | expressed protein | 0.0033 | 0.0709 | 0.0638 |
Echinococcus multilocularis | Ankyrin | 0.0014 | 0.0133 | 0.0057 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.015 | 0.0134 |
Schistosoma mansoni | lamin | 0.0053 | 0.1331 | 0.1218 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0032 | 0.0685 | 0.4442 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0013 | 0.0076 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.1331 | 0.1218 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1543 | 1 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0429 | 0.0543 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0615 | 0.0543 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0501 | 0.0649 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0388 | 0.0262 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.0482 | 0.0409 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.066 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0482 | 0.0598 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0035 | 0.0782 | 0.628 |
Wolbachia endosymbiont of Brugia malayi | parvulin-like peptidyl-prolyl isomerase, PPID | 0.001 | 0 | 0.5 |
Echinococcus multilocularis | transcription factor btf3 | 0.0034 | 0.0751 | 0.068 |
Leishmania major | protein kinase, putative | 0.0013 | 0.0076 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1301 | 0.1805 |
Onchocerca volvulus | 0.0036 | 0.0789 | 0.1045 | |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0076 | 0.0609 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.071 | 0.0954 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.071 | 0.0954 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.3001 | 1 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0076 | 0.0026 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.1331 | 0.1265 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0429 | 0.0543 |
Brugia malayi | Protein kinase domain containing protein | 0.0014 | 0.0129 | 0.000000094094 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0013 | 0.0076 | 0.0026 |
Echinococcus granulosus | Ankyrin | 0.0014 | 0.0133 | 0.0057 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.1245 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.066 | 0.0589 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.061 | 0.0807 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0015 | 0.015 | 0.0075 |
Onchocerca volvulus | 0.0234 | 0.6897 | 1 | |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0233 | 0.6862 | 0.6838 |
Onchocerca volvulus | 0.0028 | 0.0561 | 0.0711 | |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0034 | 0.0751 | 0.0282 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0861 | 0.1174 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0076 | 0.0026 |
Giardia lamblia | GTOR | 0.0045 | 0.1061 | 0.5 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0076 | 0.0026 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins | ChEMBL. | 21903399 | |
Inhibition (binding) | Inhibition of recombinant His-tagged human DNA polymerase lambda using bovine deoxyribonuclease 1-treated DNA and dNTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins | ChEMBL. | 21903399 | |
Inhibition (binding) | Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using bovine deoxyribonuclease 1-treated DNA and dNTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins | ChEMBL. | 21903399 | |
Inhibition (binding) | Inhibition of recombinant His-tagged human DNA polymerase lambda using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins | ChEMBL. | 21903399 | |
LD50 (ADMET) | > 10 uM | Cytotoxicity against mouse RAW264.7 cells | ChEMBL. | 21903399 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.