Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Echinococcus granulosus | protein jagged 2 | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Brugia malayi | Cadherin domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Brugia malayi | EGF-like domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0284 | 0.3868 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0284 | 0.3868 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0284 | 0.3868 | 1 |
Schistosoma mansoni | notch | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.1086 | 0.0678 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0092 | 0.1086 | 0.0678 |
Schistosoma mansoni | slit | 0.0092 | 0.1086 | 0.0678 |
Brugia malayi | Muscle positioning protein 4 | 0.0092 | 0.1086 | 0.2808 |
Echinococcus multilocularis | protein jagged 1 | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Echinococcus multilocularis | fibropellin Ia | 0.0092 | 0.1086 | 0.0678 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.1086 | 0.0678 |
Onchocerca volvulus | Dual oxidase homolog | 0.0284 | 0.3868 | 1 |
Schistosoma mansoni | peroxidasin | 0.0284 | 0.3868 | 0.3587 |
Onchocerca volvulus | Peroxidase homolog | 0.0284 | 0.3868 | 1 |
Onchocerca volvulus | 0.0284 | 0.3868 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Echinococcus granulosus | peroxidasin | 0.0284 | 0.3868 | 0.3587 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0092 | 0.1086 | 0.0678 |
Onchocerca volvulus | 0.0284 | 0.3868 | 1 | |
Echinococcus granulosus | delta-like protein 1 | 0.0092 | 0.1086 | 0.0678 |
Schistosoma mansoni | notch | 0.0092 | 0.1086 | 0.0678 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0092 | 0.1086 | 0.2808 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0133 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0092 | 0.1086 | 0.2808 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0284 | 0.3868 | 0.3587 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Brugia malayi | Peroxidasin | 0.0284 | 0.3868 | 1 |
Echinococcus granulosus | protein jagged 2 | 0.0092 | 0.1086 | 0.0678 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0708 | 1 | 1 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0092 | 0.1086 | 0.0678 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0133 | 0.0343 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0092 | 0.1086 | 0.0678 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.1086 | 0.0678 |
Echinococcus granulosus | protein jagged 1 | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Schistosoma mansoni | cell polarity protein | 0.0092 | 0.1086 | 0.0678 |
Giardia lamblia | High cysteine protein | 0.0092 | 0.1086 | 0.5 |
Onchocerca volvulus | 0.0284 | 0.3868 | 1 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0284 | 0.3868 | 1 |
Echinococcus granulosus | slit 2 protein | 0.0092 | 0.1086 | 0.0678 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Echinococcus multilocularis | slit 2 protein | 0.0092 | 0.1086 | 0.0678 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.1086 | 0.0678 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0133 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0437 | 0.1131 |
Echinococcus granulosus | fibropellin Ia | 0.0092 | 0.1086 | 0.0678 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0092 | 0.1086 | 0.0678 |
Brugia malayi | Animal haem peroxidase family protein | 0.0284 | 0.3868 | 1 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0092 | 0.1086 | 0.0678 |
Brugia malayi | Delta serrate ligand family protein | 0.0092 | 0.1086 | 0.2808 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0284 | 0.3868 | 1 |
Schistosoma mansoni | notch | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Brugia malayi | Animal haem peroxidase family protein | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | notch protein | 0.0092 | 0.1086 | 0.2553 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0437 | 0.0816 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Brugia malayi | EGF-like domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Echinococcus granulosus | neural cadherin | 0.0092 | 0.1086 | 0.0678 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.2273 | 0.192 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Brugia malayi | Animal haem peroxidase family protein | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0284 | 0.3868 | 1 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0092 | 0.1086 | 0.0678 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0284 | 0.3868 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.1086 | 0.0678 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0133 | 0.5 |
Echinococcus multilocularis | protein jagged 1 | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | Notch2 | 0.0092 | 0.1086 | 0.2553 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0133 | 0.5 |
Schistosoma mansoni | septate junction protein | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0708 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0284 | 0.3868 | 1 |
Echinococcus multilocularis | protein jagged 2 | 0.0092 | 0.1086 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Brugia malayi | notch-like transmembrane receptor | 0.0092 | 0.1086 | 0.2808 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Brugia malayi | EGF-like domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Onchocerca volvulus | Peroxidasin homolog | 0.0284 | 0.3868 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0133 | 0.5 |
Brugia malayi | hypothetical protein | 0.0284 | 0.3868 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.1086 | 0.0678 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0092 | 0.1086 | 0.0678 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0092 | 0.1086 | 0.0678 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0092 | 0.1086 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0092 | 0.1086 | 0.0678 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0133 | 0.5 |
Brugia malayi | EGF-like domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0092 | 0.1086 | 0.0678 |
Echinococcus granulosus | notch | 0.0092 | 0.1086 | 0.0678 |
Brugia malayi | Cadherin domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0133 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Schistosoma mansoni | peroxidasin | 0.0284 | 0.3868 | 0.3587 |
Schistosoma mansoni | notch | 0.0092 | 0.1086 | 0.0678 |
Brugia malayi | Blistered cuticle protein 3 | 0.0284 | 0.3868 | 1 |
Schistosoma mansoni | notch | 0.0092 | 0.1086 | 0.0678 |
Echinococcus granulosus | geminin | 0.0174 | 0.2273 | 0.192 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.3868 | 1 |
Schistosoma mansoni | notch | 0.0092 | 0.1086 | 0.0678 |
Brugia malayi | EGF-like domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Echinococcus multilocularis | notch | 0.0092 | 0.1086 | 0.0678 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.2273 | 0.192 |
Brugia malayi | EGF-like domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1086 | 0.2553 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0092 | 0.1086 | 0.2808 |
Echinococcus multilocularis | neural cadherin | 0.0092 | 0.1086 | 0.0678 |
Echinococcus multilocularis | geminin | 0.0174 | 0.2273 | 0.192 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.