TDR Targets

Basic information

Technical information

TDR Targets ID: 1568660
Name: 3-[4-methoxy-7-(oxan-4-yl)-1,3-benzothiazol-2 -yl]-1-methyl-1-(1-methylpiperidin-4-yl)urea
MW: 418.553 | Formula: C21H30N4O3S
H donors: 1 H acceptors: 2 LogP: 2.86 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc(c2c1nc(s2)NC(=O)N(C1CCN(CC1)C)C)C1CCOCC1
InChi: 1S/C21H30N4O3S/c1-24-10-6-15(7-11-24)25(2)21(26)23-20-22-18-17(27-3)5-4-16(19(18)29-20)14-8-12-28-13-9-14/h4-5,14-15H,6-13H2,1-3H3,(H,22,23,26)
InChiKey: ZZBZKKYQZNSJEQ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

3-(4-methoxy-7-tetrahydropyran-4-yl-1,3-benzothiazol-2-yl)-1-methyl-1-(1-methyl-4-piperidyl)urea
3-[4-methoxy-7-(4-tetrahydropyranyl)-1,3-benzothiazol-2-yl]-1-methyl-1-(1-methyl-4-piperidinyl)urea

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma cruzi	proteasome subunit beta type-5, putative	0.0244	0.6819	1
Schistosoma mansoni	26S proteasome subunit S9	0.0036	0.0498	0.0498
Loa Loa (eye worm)	proteasome regulatory particle	0.0036	0.0498	0.0731
Echinococcus multilocularis	Proteasome, subunit alpha beta	0.0131	0.3384	0.3384
Trypanosoma cruzi	proteasome beta 3 subunit, putative	0.0123	0.3165	0.4641
Entamoeba histolytica	proteasome subunit beta type 6 precursor, putative	0.0129	0.3349	0.4911
Trypanosoma brucei	proteasome beta-1 subunit, putative	0.0129	0.3349	0.4911
Brugia malayi	proteasome subunit alpha type 1	0.0129	0.3321	0.3321
Echinococcus granulosus	26S proteasome non ATPase regulatory subunit 12	0.0032	0.0399	0.0399
Echinococcus multilocularis	26S proteasome regulatory subunit N11	0.003	0.0319	0.0319
Giardia lamblia	20S proteasome alpha subunit 3	0.0129	0.3336	0.4892
Plasmodium vivax	proteasome subunit alpha type-4, putative	0.0129	0.3336	0.4892
Giardia lamblia	26S proteasome non-ATPase regulatory subunit 2	0.0033	0.0435	0.0639
Brugia malayi	Adhesion regulating molecule conserved region family protein	0.0092	0.222	0.222
Trypanosoma brucei	proteasome beta 2 subunit, putative	0.0118	0.3001	0.4402
Loa Loa (eye worm)	proteasome A-type and B-type family protein	0.0129	0.3349	0.4911
Entamoeba histolytica	26S protease regulatory subunit, putative	0.002	0.0017	0.0025
Entamoeba histolytica	26S protease regulatory subunit, putative	0.0021	0.0053	0.0077
Schistosoma mansoni	26S proteasome non-ATPase regulatory subunit	0.0032	0.0395	0.0395
Leishmania major	hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B	0.0097	0.2377	0.3486
Toxoplasma gondii	proteasome subunit alpha type, putative	0.008	0.184	0.2699
Trypanosoma cruzi	proteasome alpha 7 subunit, putative	0.0177	0.4797	0.7035
Schistosoma mansoni	26S protease regulatory subunit 6b	0.002	0.0017	0.0017
Plasmodium vivax	26S proteasome regulatory subunit RPN1, putative	0.0033	0.0435	0.0639
Schistosoma mansoni	proteasome subunit beta 3 (T01 family)	0.0123	0.3165	0.3164
Onchocerca volvulus		0.002	0.0017	0.005
Loa Loa (eye worm)	proteasome 26S subunit	0.0019	0.0000046814	0.0000068654
Plasmodium falciparum	26S proteasome regulatory subunit RPN6	0.0036	0.0498	0.0731
Entamoeba histolytica	19S cap proteasome S2 subunit	0.002	0.0034	0.005
Toxoplasma gondii	proteasome subunit alpha type 5-2, putative	0.014	0.3674	0.5387
Plasmodium vivax	26S proteasome regulatory subunit p55, putative	0.0032	0.0399	0.0585
Echinococcus granulosus	proteasome subunit beta type 7	0.0349	1	1
Trypanosoma cruzi	proteasome alpha 1 subunit, putative	0.0141	0.3702	0.5429
Echinococcus multilocularis	adhesion regulating molecule 1	0.0092	0.222	0.222
Schistosoma mansoni	proteasome subunit alpha 1 (T01 family)	0.0129	0.3321	0.3321
Leishmania major	proteasome alpha 2 subunit, putative	0.0134	0.3484	0.5109
Toxoplasma gondii	Mov34/MPN/PAD-1 family protein	0.003	0.0319	0.0468
Loa Loa (eye worm)	26S proteasome regulatory complex subunit p97	0.0033	0.0435	0.0639
Giardia lamblia	26S protease regulatory subunit 6A	0.0021	0.0053	0.0077
Trypanosoma cruzi	proteasome beta 6 subunit, putative	0.015	0.3981	0.5839
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0122	0.3115	0.4568
Brugia malayi	Ubiquitin interaction motif family protein	0.0021	0.0051	0.0051
Trypanosoma cruzi	proteasome regulatory ATPase subunit 5, putative	0.0021	0.0053	0.0077
Plasmodium vivax	26S proteasome AAA-ATPase subunit RPT3, putative	0.002	0.0017	0.0025
Loa Loa (eye worm)	20S proteasome alpha5 subunit	0.014	0.3674	0.5387
Echinococcus granulosus	26S proteasome non ATPase regulatory subunit 4	0.0021	0.0051	0.0051
Schistosoma mansoni	26S proteasome regulatory subunit S3	0.0038	0.058	0.058
Echinococcus multilocularis	26S proteasome regulatory subunit T3	0.002	0.0017	0.0017
Giardia lamblia	26S proteasome non-ATPase regulatory subunit 6	0.0032	0.0395	0.058
Plasmodium falciparum	proteasome subunit alpha type-1, putative	0.0129	0.3321	0.4871
Giardia lamblia	Proteasome subunit beta type 3	0.0123	0.3165	0.4641
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0177	0.4797	0.7035
Schistosoma mansoni	26S protease regulatory subunit	0.002	0.0017	0.0017
Brugia malayi	proteasome subunit beta type 1	0.015	0.3981	0.3981
Echinococcus multilocularis	26s protease regulatory subunit 6a	0.0021	0.0053	0.0053
Loa Loa (eye worm)	proteasome subunit alpha type 6	0.0141	0.3702	0.5429
Plasmodium falciparum	proteasome subunit beta type-7, putative	0.0118	0.3001	0.4402
Echinococcus granulosus	proteasome subunit beta t family	0.0123	0.3165	0.3164
Toxoplasma gondii	PCI domain-containing protein	0.0029	0.0314	0.0461
Toxoplasma gondii	SAC3/GANP family protein	0.0028	0.0273	0.0401
Entamoeba histolytica	proteasome subunit alpha type 3, putative	0.0131	0.3384	0.4963
Trypanosoma brucei	proteasome beta 3 subunit, putative	0.0123	0.3165	0.4641
Echinococcus granulosus	proteasome prosome macropain subunit alpha	0.0129	0.3336	0.3336
Echinococcus multilocularis	26S proteasome non ATPase regulatory subunit 12	0.0032	0.0399	0.0399
Schistosoma mansoni	multiubiquitin binding protein S5a	0.0021	0.0051	0.0051
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0123	0.3165	0.4641
Trypanosoma cruzi	proteasome beta 2 subunit, putative	0.0118	0.3001	0.4402
Plasmodium vivax	proteasome subunit alpha type-6, putative	0.0141	0.3702	0.5429
Trypanosoma brucei	Proteasome subunit A N-terminal signature/Proteasome subunit, putative	0.0129	0.3321	0.4871
Echinococcus granulosus	proteasome 26s subunit subunit 4 atpase	0.002	0.0017	0.0017
Schistosoma mansoni	proteasome catalytic subunit 2 (T01 family)	0.0349	1	1
Plasmodium vivax	proteasome subunit beta type-2, putative	0.0123	0.3165	0.4641
Echinococcus multilocularis	26S proteasome non ATPase regulatory subunit 8	0.0028	0.0273	0.0273
Entamoeba histolytica	proteasome subunit beta type 1, putative	0.015	0.3981	0.5839
Giardia lamblia	Proteasome subunit beta type 7 precursor	0.0118	0.3001	0.4402
Loa Loa (eye worm)	proteasome subunit alpha type 3	0.0131	0.3384	0.4963
Schistosoma mansoni	26S proteasome non-ATPase regulatory subunit 7	0.003	0.0319	0.0319
Leishmania major	proteasome regulatory non-ATP-ase subunit 3, putative	0.0038	0.058	0.085
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0273	0.0401
Leishmania major	proteasome regulatory non-ATP-ase subunit, putative	0.0029	0.0314	0.0461
Giardia lamblia	Proteasome subunit beta type 5 precursor	0.0244	0.6819	1
Brugia malayi	26S proteasome subunit P45 family protein	0.002	0.0017	0.0017
Echinococcus multilocularis	26S proteasome non ATPase regulatory subunit 7	0.003	0.0319	0.0319
Plasmodium vivax	proteasome subunit beta type-3, putative	0.0123	0.3165	0.4641
Echinococcus multilocularis	26S proteasome regulatory subunit S3	0.0038	0.058	0.058
Brugia malayi	Proteasome subunit alpha type 7-1	0.0177	0.4797	0.4797
Plasmodium falciparum	26S proteasome regulatory subunit RPN3, putative	0.0038	0.058	0.085
Brugia malayi	Probable 26S proteasome non-ATPase regulatory subunit 3	0.0038	0.058	0.058
Leishmania major	proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative	0.015	0.3981	0.5839
Toxoplasma gondii	proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative	0.0134	0.3484	0.5109
Echinococcus granulosus	20S proteasome subunit alpha 6	0.0129	0.3321	0.3321
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0123	0.3165	0.4641
Echinococcus granulosus	26s proteasome regulatory particle subunit	0.0033	0.0435	0.0435
Toxoplasma gondii	26s proteasome subunit p55, putative	0.0032	0.0399	0.0585
Echinococcus granulosus	proteasome prosome macropain subunit beta type	0.0122	0.3115	0.3115
Loa Loa (eye worm)	PCI domain-containing protein	0.0029	0.0314	0.0461
Plasmodium falciparum	proteasome subunit beta type-2, putative	0.0123	0.3165	0.4641
Leishmania major	proteasome beta 7 subunit, putative	0.0122	0.3115	0.4568
Trichomonas vaginalis	26S protease regulatory subunit 6A, putative	0.002	0.0017	0.0025
Giardia lamblia	20S proteasome alpha subunit 6	0.0129	0.3321	0.4871
Leishmania major	proteasome regulatory ATPase subunit 5, putative	0.0021	0.0053	0.0077
Entamoeba histolytica	proteasome subunit alpha type 4, putative	0.0129	0.3336	0.4892
Trypanosoma cruzi	proteasome regulatory ATPase subunit 2, putative	0.002	0.0017	0.0025
Trichomonas vaginalis	cop9 signalosome complex subunit, putative	0.0032	0.0395	0.058
Loa Loa (eye worm)	hypothetical protein	0.0092	0.222	0.3256
Echinococcus granulosus	adhesion regulating molecule 1	0.0092	0.222	0.222
Giardia lamblia	20S proteasome alpha subunit 2	0.0134	0.3484	0.5109
Echinococcus multilocularis	DSS1 (SEM1) domain containing protein	0.0085	0.2013	0.2013
Echinococcus granulosus	26S proteasome regulatory subunit T3	0.002	0.0017	0.0017
Echinococcus multilocularis	26S proteasome non ATPase regulatory subunit	0.0036	0.0498	0.0498
Trichomonas vaginalis	proteasome regulatory subunits, putative	0.0032	0.0399	0.0585
Loa Loa (eye worm)	hypothetical protein	0.002	0.0017	0.0025
Toxoplasma gondii	proteasome subunit alpha type, putative	0.0129	0.3336	0.4892
Brugia malayi	Probable 26S protease regulatory subunit 4	0.002	0.0017	0.0017
Giardia lamblia	26S protease regulatory subunit 6B	0.002	0.0017	0.0025
Entamoeba histolytica	proteasome subunit beta Type 4 precursor, putative	0.0122	0.3115	0.4568
Schistosoma mansoni	proteasome subunit alpha 2 (T01 family)	0.0134	0.3484	0.3484
Leishmania major	proteasome alpha 3 subunit, putative	0.0129	0.3336	0.4892
Leishmania major	proteasome beta 2 subunit, putative	0.0123	0.3165	0.4641
Echinococcus granulosus	proteasome prosome macropain subunit beta	0.015	0.3981	0.3981
Plasmodium vivax	ATP-dependent protease subunit ClpQ, putative	0.0097	0.2377	0.3486
Trypanosoma brucei	proteasome alpha 1 subunit, putative	0.0141	0.3702	0.5429
Leishmania major	proteasome regulatory non-ATPase subunit, putative	0.0033	0.0435	0.0639
Echinococcus multilocularis	Proteasome subunit alpha type 7	0.0177	0.4797	0.4797
Trichomonas vaginalis	Clan MP, family M67, Poh1-like metallopeptidase	0.003	0.0319	0.0468
Trypanosoma cruzi	proteasome subunit alpha type-5, putative	0.014	0.3674	0.5387
Giardia lamblia	Proteasome subunit beta type 9 precursor	0.0129	0.3349	0.4911
Trypanosoma brucei	proteasome regulatory non-ATP-ase subunit 9	0.0029	0.0314	0.0461
Plasmodium falciparum	26S proteasome regulatory subunit RPN7, putative	0.0032	0.0395	0.058
Entamoeba histolytica	proteasome regulatory subunit, putative	0.0032	0.0399	0.0585
Loa Loa (eye worm)	proteasome subunit beta type 1	0.015	0.3981	0.5839
Trypanosoma brucei	proteasome regulatory ATPase subunit 5	0.0021	0.0053	0.0077
Plasmodium vivax	proteasome subunit beta type-1, putative	0.015	0.3981	0.5839
Schistosoma mansoni	proteasome catalytic subunit 1 (T01 family)	0.0129	0.3349	0.3349
Trypanosoma brucei	proteasome regulatory non-ATPase subunit 6	0.0036	0.0498	0.0731
Loa Loa (eye worm)	RPN-3 protein	0.0038	0.058	0.085
Leishmania major	proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit	0.0032	0.0399	0.0585
Echinococcus granulosus	proteasome prosome macropain	0.0244	0.6819	0.6819
Schistosoma mansoni	hypothetical protein	0.0085	0.2013	0.2013
Leishmania major	proteasome alpha 7 subunit, putative	0.0177	0.4797	0.7035
Trypanosoma brucei	proteasome regulatory non-ATP-ase subunit 3	0.0038	0.058	0.085
Brugia malayi	26S proteasome non-ATPase regulatory subunit 7, putative	0.003	0.0319	0.0319
Toxoplasma gondii	proteasome subunit beta type 7 precursor, putative	0.0118	0.3001	0.4402
Trypanosoma cruzi	ATP-dependent protease subunit HslV, putative	0.0097	0.2377	0.3486
Giardia lamblia	26S proteasome ATPase subunit S4, putative	0.002	0.0017	0.0025
Schistosoma mansoni	subfamily T1A non-peptidase homologue (T01 family)	0.014	0.3674	0.3674
Giardia lamblia	Proteasome subunit beta type 1	0.015	0.3981	0.5839
Schistosoma mansoni	proteasome subunit beta 2 (T01 family)	0.0123	0.3165	0.3164
Schistosoma mansoni	proteasome subunit beta 4 (T01 family)	0.0122	0.3115	0.3115
Loa Loa (eye worm)	proteasome Regulatory Particle	0.0032	0.0395	0.058
Echinococcus granulosus	subfamily T1A non peptidase ue	0.014	0.3674	0.3674
Brugia malayi	PCI domain containing protein	0.0032	0.0399	0.0399
Trypanosoma brucei	proteasome alpha 2 subunit, putative	0.0134	0.3484	0.5109
Trypanosoma brucei	proteasome regulatory ATPase subunit 2	0.002	0.0017	0.0025
Plasmodium falciparum	proteasome subunit alpha type-4, putative	0.0129	0.3336	0.4892
Entamoeba histolytica	proteasome subunit alpha type 2-A, putative	0.0134	0.3484	0.5109
Brugia malayi	proteasome subunit alpha type 2	0.0134	0.3484	0.3484
Schistosoma mansoni	26S protease regulatory subunit 6a	0.0021	0.0053	0.0053
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0129	0.3321	0.4871
Trypanosoma cruzi	proteasome regulatory non-ATPase subunit, putative	0.0028	0.0273	0.0401
Trichomonas vaginalis	26S protease regulatory subunit, putative	0.002	0.0017	0.0025
Schistosoma mansoni	26S protease regulatory subunit 6a	0.0021	0.0053	0.0053
Schistosoma mansoni	adhesion regulating molecule 1 (110 kD cell membrane glycoprotein)	0.0092	0.222	0.222
Echinococcus multilocularis	20S proteasome subunit alpha 6	0.0129	0.3321	0.3321
Entamoeba histolytica	proteasome subunit beta type 7-B precursor, putative	0.0118	0.3001	0.4402
Entamoeba histolytica	proteasome subunit alpha type 6, putative	0.0141	0.3702	0.5429
Giardia lamblia	20S proteasome alpha subunit 7	0.0131	0.3384	0.4963
Echinococcus granulosus	26S proteasome non ATPase regulatory subunit 8	0.0028	0.0273	0.0273
Trypanosoma cruzi	proteasome alpha 1 subunit, putative	0.0141	0.3702	0.5429
Trypanosoma cruzi	proteasome regulatory non-ATP-ase subunit 9, putative	0.0029	0.0314	0.0461
Schistosoma mansoni	proteasome subunit beta 3 (T01 family)	0.0123	0.3165	0.3164
Trypanosoma brucei	proteasome regulatory ATPase subunit 3	0.002	0.0017	0.0025
Plasmodium vivax	26S proteasome regulatory subunit RPN9, putative	0.0029	0.0314	0.0461
Schistosoma mansoni	proteasome subunit alpha 4 (T01 family)	0.0129	0.3336	0.3336
Plasmodium falciparum	proteasome subunit beta type-5	0.0244	0.6819	1
Schistosoma mansoni	proteasome subunit alpha 6 (T01 family)	0.0141	0.3702	0.3702
Toxoplasma gondii	proteasome subunit alpha type 1, putative	0.0129	0.3321	0.4871
Plasmodium falciparum	26S proteasome regulatory subunit RPN1, putative	0.0033	0.0435	0.0639
Echinococcus granulosus	Proteasome subunit alpha type 7	0.0177	0.4797	0.4797
Schistosoma mansoni	26s proteasome regulatory particle subunit	0.0033	0.0435	0.0435
Plasmodium falciparum	26S proteasome regulatory subunit RPN8, putative	0.003	0.0319	0.0468
Trypanosoma cruzi	proteasome regulatory ATPase subunit 5, putative	0.0021	0.0053	0.0077
Entamoeba histolytica	proteasome subunit alpha type 1, putative	0.0129	0.3321	0.4871
Plasmodium vivax	26S proteasome regulatory subunit RPN7, putative	0.0032	0.0395	0.058
Brugia malayi	Proteasome A-type and B-type family protein	0.0129	0.3349	0.3349
Trypanosoma cruzi	proteasome beta 6 subunit, putative	0.015	0.3981	0.5839
Trypanosoma cruzi	proteasome alpha 3 subunit, putative	0.0129	0.3336	0.4892
Echinococcus multilocularis	proteasome 26s subunit subunit 4 atpase	0.002	0.0017	0.0017
Toxoplasma gondii	proteasome subunit beta type 2, putative	0.0123	0.3165	0.4641
Trichomonas vaginalis	26S proteasome non-ATPase regulatory subunit, putative	0.0028	0.0273	0.0401
Trypanosoma brucei	proteasome regulatory non-ATP-ase subunit	0.0028	0.0273	0.0401
Trypanosoma cruzi	proteasome regulatory ATPase subunit 3, putative	0.002	0.0017	0.0025
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0122	0.3115	0.4568
Toxoplasma gondii	26S proteasome regulatory subunit 6b, putative	0.002	0.0017	0.0025
Entamoeba histolytica	proteasome subunit alpha type 5, putative	0.014	0.3674	0.5387
Schistosoma mansoni	proteasome subunit alpha 7 (T01 family)	0.0177	0.4797	0.4797
Plasmodium falciparum	ATP-dependent protease subunit ClpQ	0.0097	0.2377	0.3486
Toxoplasma gondii	PCI domain-containing protein	0.0038	0.058	0.085
Echinococcus granulosus	proteasome prosome macropain subunit beta	0.0123	0.3165	0.3164
Trichomonas vaginalis	26S proteasome subunit S9, putative	0.0036	0.0498	0.0731
Trypanosoma cruzi	proteasome beta-1 subunit, putative	0.0129	0.3349	0.4911
Trichomonas vaginalis	26S proteasome non-ATPase regulatory subunit, putative	0.0021	0.0051	0.0074
Brugia malayi	proteasome subunit beta type 3	0.0123	0.3165	0.3164
Plasmodium falciparum	proteasome subunit beta type-6, putative	0.0129	0.3349	0.4911
Echinococcus granulosus	26S proteasome non ATPase regulatory subunit	0.0036	0.0498	0.0498
Leishmania major	hypothetical protein, conserved	0.0048	0.0879	0.1289
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0208	0.0304
Plasmodium falciparum	26S proteasome regulatory subunit p55, putative	0.0032	0.0399	0.0585
Leishmania major	proteasome beta-1 subunit, putative	0.0129	0.3349	0.4911
Plasmodium vivax	proteasome subunit alpha type-3, putative	0.0131	0.3384	0.4963
Echinococcus multilocularis	proteasome (prosome, macropain) subunit, beta	0.0123	0.3165	0.3164
Entamoeba histolytica	proteasome regulatory subunit, putative	0.0028	0.0273	0.0401
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0122	0.3115	0.4568
Loa Loa (eye worm)	proteasome subunit beta type 2	0.0123	0.3165	0.4641
Loa Loa (eye worm)	26S protease regulatory subunit 8	0.0019	0.0000046814	0.0000068654
Plasmodium falciparum	26S proteasome regulatory subunit RPN11, putative	0.003	0.0319	0.0468
Echinococcus multilocularis	26S proteasome non ATPase regulatory subunit 4	0.0021	0.0051	0.0051
Trypanosoma cruzi	proteasome regulatory non-ATP-ase subunit 7, putative	0.0029	0.0289	0.0423
Giardia lamblia	20S proteasome alpha subunit 1	0.0141	0.3702	0.5429
Leishmania major	proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative	0.003	0.0319	0.0468
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.015	0.3981	0.5839
Echinococcus multilocularis	proteasome subunit alpha type 2	0.0134	0.3484	0.3484
Trypanosoma cruzi	proteasome alpha 7 subunit, putative	0.0177	0.4797	0.7035
Toxoplasma gondii	PCI domain-containing protein	0.0036	0.0498	0.0731
Loa Loa (eye worm)	proteasome subunit alpha type 1	0.0129	0.3321	0.4871
Plasmodium vivax	proteasome subunit alpha type-5, putative	0.014	0.3674	0.5387
Echinococcus multilocularis	proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta	0.0123	0.3165	0.3164
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0118	0.3001	0.4402
Schistosoma mansoni	26s proteasome regulatory particle subunit	0.0033	0.0435	0.0435
Trypanosoma brucei	proteasome regulatory non-ATP-ase subunit 5	0.0032	0.0399	0.0585
Schistosoma mansoni	proteasome subunit beta 2 (T01 family)	0.0097	0.2377	0.2377
Toxoplasma gondii	proteasome subunit beta type, putative	0.0244	0.6819	1
Plasmodium vivax	proteasome subunit alpha type-7, putative	0.0177	0.4797	0.7035
Toxoplasma gondii	20S proteasome subunit beta 7, putative	0.0122	0.3115	0.4568
Trypanosoma cruzi	proteasome alpha 7 subunit, putative	0.0131	0.3384	0.4963
Trypanosoma cruzi	26S proteasome regulatory non-ATPase subunit, putative	0.002	0.0034	0.005
Trypanosoma cruzi	20S proteasome subunit	0.0123	0.3165	0.4641
Plasmodium vivax	26S protease regulatory subunit 6a, putative	0.0021	0.0053	0.0077
Mycobacterium leprae	proteasome (beta subunit) PrcB	0.0244	0.6819	1
Plasmodium falciparum	proteasome subunit alpha type-6, putative	0.0141	0.3702	0.5429
Trypanosoma cruzi	proteasome alpha 3 subunit, putative	0.0129	0.3336	0.4892
Schistosoma mansoni	proteasome subunit beta 1 (T01 family)	0.015	0.3981	0.3981
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0122	0.3115	0.4568
Toxoplasma gondii	proteasome regulatory subunit	0.003	0.0319	0.0468
Leishmania major	proteasome alpha 7 subunit, putative	0.0131	0.3384	0.4963
Plasmodium falciparum	proteasome subunit beta type-1, putative	0.015	0.3981	0.5839
Giardia lamblia	Proteasome subunit beta type 4 precursor	0.0122	0.3115	0.4568
Trichomonas vaginalis	26S proteasome non-ATPase regulatory subunit, putative	0.0028	0.0273	0.0401
Trypanosoma brucei	proteasome subunit alpha type-5, putative	0.014	0.3674	0.5387
Echinococcus granulosus	26S proteasome regulatory subunit S3	0.0038	0.058	0.058
Brugia malayi	proteasome subunit alpha type 4	0.0113	0.2854	0.2854
Plasmodium vivax	proteasome subunit beta type-4, putative	0.0122	0.3115	0.4568
Leishmania major	proteasome alpha 1 subunit, putative	0.0129	0.3321	0.4871
Toxoplasma gondii	proteasome beta subunit	0.0123	0.3165	0.4641
Mycobacterium ulcerans	proteasome PrcB	0.0244	0.6819	1
Loa Loa (eye worm)	hypothetical protein	0.002	0.0017	0.0025
Entamoeba histolytica	proteasome subunit alpha type 5, putative	0.014	0.3674	0.5387
Schistosoma mansoni	26S proteasome non-ATPase regulatory subunit	0.0028	0.0273	0.0273
Brugia malayi	26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein	0.0028	0.0273	0.0273
Toxoplasma gondii	adhesion regulating molecule region protein, putative	0.0092	0.222	0.3256
Trypanosoma brucei	proteasome alpha 7 subunit, putative	0.0177	0.4797	0.7035
Toxoplasma gondii	proteasome subunit beta type 1, putative	0.015	0.3981	0.5839
Entamoeba histolytica	probable proteasome subunit beta type 2, putative	0.0123	0.3165	0.4641
Trypanosoma brucei	26S proteasome regulatory non-ATPase subunit	0.0033	0.0435	0.0639
Onchocerca volvulus		0.002	0.0017	0.005
Entamoeba histolytica	26S proteasome non-ATPase regulatory subunit, putative	0.003	0.0319	0.0468
Trypanosoma cruzi	proteasome alpha 7 subunit, putative	0.0131	0.3384	0.4963
Plasmodium vivax	26S proteasome regulatory subunit RPN11, putative	0.003	0.0319	0.0468
Entamoeba histolytica	proteasome regulatory subunit, putative	0.0038	0.058	0.085
Entamoeba histolytica	proteasome regulatory subunit, putative	0.0036	0.0498	0.0731
Toxoplasma gondii	proteasome 26S regulatory subunit	0.002	0.0034	0.005
Entamoeba histolytica	proteasome subunit alpha type 7, putative	0.0177	0.4797	0.7035
Echinococcus multilocularis	subfamily T1A non peptidase ue	0.014	0.3674	0.3674
Giardia lamblia	20S proteasome alpha subunit 5	0.014	0.3674	0.5387
Trichomonas vaginalis	26S protease regulatory subunit, putative	0.002	0.0017	0.0025
Echinococcus multilocularis	proteasome subunit beta type 7	0.0349	1	1
Trichomonas vaginalis	26S proteasome subunit, putative	0.0029	0.0314	0.0461
Brugia malayi	20S proteasome alpha5 subunit	0.014	0.3674	0.3674
Schistosoma mansoni	26S protease regulatory subunit 6a	0.0021	0.0053	0.0053
Trypanosoma cruzi	proteasome alpha 2 subunit, putative	0.0134	0.3484	0.5109
Trypanosoma brucei	19S proteasome non-atpase subunit 8	0.003	0.0319	0.0468
Onchocerca volvulus	Notchless protein homolog	0.0131	0.3384	1
Trichomonas vaginalis	26S proteasome regulatory subunit, putative	0.0033	0.0435	0.0639
Entamoeba histolytica	proteasome subunit beta type 3, putative	0.0123	0.3165	0.4641
Echinococcus multilocularis	proteasome subunit beta type 6	0.0129	0.3349	0.3349
Schistosoma mansoni	proteasome regulatory subunit-related	0.0032	0.0399	0.0399
Plasmodium falciparum	26S proteasome regulatory subunit RPN12, putative	0.0028	0.0273	0.0401
Schistosoma mansoni	26S proteasome regulatory subunit S3	0.0038	0.058	0.058
Plasmodium falciparum	proteasome subunit alpha type-3, putative	0.0131	0.3384	0.4963
Brugia malayi	proteasome subunit beta type 2	0.0123	0.3165	0.3164
Onchocerca volvulus	Proteasomal ubiquitin receptor ADRM1 homolog	0.0059	0.1198	0.354
Loa Loa (eye worm)	proteasome subunit alpha type 2	0.0134	0.3484	0.5109
Trypanosoma brucei	proteasome alpha 7 subunit	0.0131	0.3384	0.4963
Plasmodium vivax	proteasome subunit beta type-6, putative	0.0129	0.3349	0.4911
Loa Loa (eye worm)	proteasome subunit beta type 3	0.0123	0.3165	0.4641
Toxoplasma gondii	26s proteasome regulatory complex subunit, putative	0.0032	0.0395	0.058
Trypanosoma brucei	proteasome subunit beta type-5, putative	0.0244	0.6819	1
Toxoplasma gondii	26S proteasome regulatory subunit, S6a family AAA ATpase	0.0021	0.0053	0.0077
Brugia malayi	26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein	0.0028	0.0273	0.0273
Leishmania major	proteasome regulatory ATPase subunit 2, putative	0.002	0.0017	0.0025
Entamoeba histolytica	proteasome subunit alpha type 4, putative	0.0129	0.3336	0.4892
Echinococcus granulosus	26S proteasome non ATPase regulatory subunit 6	0.0032	0.0395	0.0395
Plasmodium falciparum	26S proteasome regulatory subunit RPN13, putative	0.0048	0.0879	0.1289
Plasmodium vivax	26S protease regulatory subunit 4, putative	0.002	0.0017	0.0025
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0244	0.6819	1
Toxoplasma gondii	proteasome subunit alpha1, putative	0.0141	0.3702	0.5429
Plasmodium falciparum	26S protease regulatory subunit 6B, putative	0.002	0.0017	0.0025
Entamoeba histolytica	proteasome regulatory subunit, putative	0.0029	0.0314	0.0461
Trypanosoma cruzi	proteasome regulatory non-ATPase subunit, putative	0.0021	0.0051	0.0074
Plasmodium vivax	26S proteasome regulatory subunit RPN8, putative	0.003	0.0319	0.0468
Loa Loa (eye worm)	26S proteasome non-ATPase regulatory subunit 7	0.003	0.0319	0.0468
Wolbachia endosymbiont of Brugia malayi	ATP-dependent protease peptidase subunit	0.0097	0.2377	0.5
Entamoeba histolytica	proteasome regulatory subunit, putative	0.0032	0.0395	0.058
Loa Loa (eye worm)	proteasome subunit alpha type 7-1	0.0177	0.4797	0.7035
Brugia malayi	Hypothetical 35.8 kDa protein F37A4.5 in chromosome III	0.003	0.0319	0.0319
Leishmania major	proteasome regulatory ATPase subunittcc1l8.3, putative	0.002	0.0017	0.0025
Trypanosoma cruzi	26S proteasome regulatory non-ATPase subunit, putative	0.0033	0.0435	0.0639
Trichomonas vaginalis	Clan MP, family M67, Poh1-like metallopeptidase	0.003	0.0319	0.0468
Loa Loa (eye worm)	proteasome A-type and B-type family protein	0.0244	0.6819	1
Entamoeba histolytica	26S proteasome non-ATPase regulatory subunit 14, putative	0.003	0.0319	0.0468
Echinococcus multilocularis	Proteasome subunit alpha type 7	0.0177	0.4797	0.4797
Trypanosoma brucei	proteasome alpha 3 subunit, putative	0.0129	0.3336	0.4892
Brugia malayi	Proteasome A-type and B-type family protein	0.0122	0.3115	0.3115
Leishmania major	proteasome regulatory non-ATPase subunit 6, putative	0.0036	0.0498	0.0731
Leishmania major	proteasome beta 2 subunit, putative	0.0118	0.3001	0.4402
Echinococcus granulosus	DSS1 SEM1 domain containing protein	0.0085	0.2013	0.2013
Leishmania major	proteasome regulatory non-ATP-ase subunit, putative	0.0028	0.0273	0.0401
Echinococcus multilocularis	Proteasome subunit alpha type 7	0.0177	0.4797	0.4797
Leishmania major	proteasome beta 5 subunit, putative	0.0244	0.6819	1
Trypanosoma cruzi	proteasome regulatory non-ATPase subunit 7, putative	0.0032	0.0395	0.058
Leishmania major	proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative)	0.014	0.3674	0.5387
Echinococcus multilocularis	proteasome (prosome, macropain) subunit, beta	0.015	0.3981	0.3981
Brugia malayi	Chain A, Structure Of A Brca2-Dss1 Complex.	0.021	0.5786	0.5786
Entamoeba histolytica	calcium-dependent protein kinase 2, putative	0.0097	0.2377	0.3486
Schistosoma mansoni	subfamily T1A non-peptidase homologue (T01 family)	0.0124	0.3191	0.3191
Toxoplasma gondii	26S protease regulatory subunit 4, putative	0.002	0.0017	0.0025
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.014	0.3674	0.5387
Leishmania major	proteasome beta 3 subunit, putative	0.0123	0.3165	0.4641
Toxoplasma gondii	hypothetical protein	0.0026	0.0208	0.0304
Trypanosoma cruzi	proteasome beta 3 subunit, putative	0.0123	0.3165	0.4641
Plasmodium falciparum	26S proteasome regulatory subunit RPN9, putative	0.0029	0.0314	0.0461
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0122	0.3115	0.4568
Trypanosoma brucei	proteasome beta 7 subunit	0.0122	0.3115	0.4568
Entamoeba histolytica	proteasome subunit alpha type 3, putative	0.0131	0.3384	0.4963
Entamoeba histolytica	proteasome regulatory subunit, putative	0.0021	0.0051	0.0074
Plasmodium vivax	proteasome subunit beta type-5, putative	0.0244	0.6819	1
Plasmodium falciparum	proteasome subunit alpha type-2, putative	0.0134	0.3484	0.5109
Toxoplasma gondii	proteasome subunit	0.0129	0.3349	0.4911
Brugia malayi	proteasome subunit alpha type 3	0.0131	0.3384	0.3384
Plasmodium vivax	proteasome subunit alpha type-1, putative	0.0129	0.3321	0.4871
Trichomonas vaginalis	26S protease regulatory subunit, putative	0.0021	0.0053	0.0077
Schistosoma mansoni	proteasome subunit alpha 3 (T01 family)	0.0131	0.3384	0.3384
Brugia malayi	26S proteasome regulatory complex subunit p97	0.0033	0.0435	0.0435
Trypanosoma cruzi	proteasome regulatory ATPase subunit 3, putative	0.002	0.0017	0.0025
Plasmodium vivax	proteasome subunit beta type-7, putative	0.0118	0.3001	0.4402
Echinococcus granulosus	Proteasome subunit alpha beta	0.0131	0.3384	0.3384
Plasmodium falciparum	proteasome subunit beta type-4	0.0122	0.3115	0.4568
Trypanosoma cruzi	proteasome regulatory non-ATPase subunit, putative	0.0021	0.0051	0.0074
Echinococcus multilocularis	26s proteasome regulatory particle subunit	0.0033	0.0435	0.0435
Giardia lamblia	Proteasome subunit beta type 2	0.0123	0.3165	0.4641
Leishmania major	proteasome regulatory non-ATP-ase subunit, putative	0.0032	0.0395	0.058
Echinococcus granulosus	proteasome subunit alpha type 2	0.0134	0.3484	0.3484
Trypanosoma cruzi	19S proteasome non-atpase subunit 8	0.003	0.0319	0.0468
Entamoeba histolytica	26S protease regulatory subunit, putative	0.002	0.0017	0.0025
Echinococcus granulosus	26S proteasome regulatory subunit N1	0.0029	0.0314	0.0314
Mycobacterium tuberculosis	Proteasome beta subunit PrcB; assembles with alpha subunit PrcA.	0.0244	0.6819	1
Trypanosoma cruzi	proteasome regulatory non-ATP-ase subunit 5, putative	0.0032	0.0399	0.0585
Trypanosoma cruzi	proteasome regulatory non-ATPase subunit 3, putative	0.0038	0.058	0.085
Echinococcus granulosus	proteasome subunit beta type 6	0.0129	0.3349	0.3349
Trypanosoma brucei	ATP-dependent protease subunit HslV	0.0097	0.2377	0.3486
Trypanosoma cruzi	proteasome beta-1 subunit, putative	0.0129	0.3349	0.4911
Brugia malayi	26S proteasome regulatory subunit rpn11	0.003	0.0319	0.0319
Loa Loa (eye worm)	proteasome A-type and B-type family protein	0.0122	0.3115	0.4568
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0273	0.0401
Trypanosoma cruzi	proteasome regulatory ATPase subunit 2, putative	0.002	0.0017	0.0025
Loa Loa (eye worm)	RPT-2 protein	0.002	0.0017	0.0025
Brugia malayi	proteasome subunit alpha type 6	0.0141	0.3702	0.3702
Loa Loa (eye worm)	26S protease regulatory subunit 6A	0.0021	0.0053	0.0077
Echinococcus multilocularis	proteasome (prosome macropain) subunit beta type	0.0122	0.3115	0.3115
Echinococcus granulosus	26S proteasome non ATPase regulatory subunit 7	0.003	0.0319	0.0319
Loa Loa (eye worm)	PCI domain-containing protein	0.0032	0.0399	0.0585
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0122	0.3115	0.4568
Plasmodium falciparum	26S protease regulatory subunit 4, putative	0.002	0.0017	0.0025
Schistosoma mansoni	proteasome catalytic subunit 3 (T01 family)	0.0244	0.6819	0.6819
Trypanosoma cruzi	proteasome beta 7 subunit, putative	0.0122	0.3115	0.4568
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0131	0.3384	0.4963
Loa Loa (eye worm)	hypothetical protein	0.021	0.5786	0.8485
Plasmodium vivax	proteasome subunit alpha type-2, putative	0.0134	0.3484	0.5109
Schistosoma mansoni	26s proteasome non-ATPase regulatory subunit 4	0.0021	0.0051	0.0051
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0141	0.3702	0.5429
Brugia malayi	26S protease regulatory subunit 6A	0.0021	0.0053	0.0053
Trypanosoma cruzi	19S proteasome non-atpase subunit 8	0.003	0.0319	0.0468
Giardia lamblia	20S proteasome alpha subunit 4	0.0177	0.4797	0.7035
Echinococcus multilocularis	26S proteasome non ATPase regulatory subunit 6	0.0032	0.0395	0.0395
Plasmodium vivax	26S proteasome regulatory subunit RPN6, putative	0.0036	0.0498	0.0731
Trypanosoma brucei	proteasome subunit beta type-2, putative	0.0123	0.3165	0.4641
Echinococcus multilocularis	26S proteasome regulatory subunit N1	0.0029	0.0314	0.0314
Brugia malayi	Proteasome subunit alpha type 1	0.0113	0.2839	0.2839
Echinococcus multilocularis	proteasome subunit alpha type 6	0.0141	0.3702	0.3702
Brugia malayi	Probable 26S proteasome non-ATPase regulatory subunit 6	0.0032	0.0395	0.0395
Trypanosoma cruzi	proteasome alpha 2 subunit, putative	0.0118	0.3001	0.4402
Brugia malayi	PCI domain containing protein	0.0029	0.0314	0.0314
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0123	0.3165	0.4641
Plasmodium falciparum	proteasome subunit alpha type-7, putative	0.0177	0.4797	0.7035
Loa Loa (eye worm)	26S proteasome regulatory subunit rpn11	0.003	0.0319	0.0468
Loa Loa (eye worm)	PAS-3 protein	0.0113	0.2854	0.4185
Trypanosoma cruzi	proteasome subunit alpha type-1, putative	0.0129	0.3321	0.4871
Trypanosoma cruzi	proteasome subunit beta type-2, putative	0.0123	0.3165	0.4641
Echinococcus granulosus	proteasome subunit alpha type 6	0.0141	0.3702	0.3702
Plasmodium falciparum	proteasome subunit beta type-3, putative	0.0123	0.3165	0.4641
Trichomonas vaginalis	26S proteasome regulatory subunit S3, putative	0.0021	0.0052	0.0076
Trypanosoma brucei	proteasome regulatory non-ATP-ase subunit 7	0.0032	0.0395	0.058
Plasmodium vivax	26S proteasome regulatory subunit RPN12, putative	0.0028	0.0273	0.0401
Trypanosoma cruzi	hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B	0.0097	0.2377	0.3486
Schistosoma mansoni	hypothetical protein	0.0029	0.0314	0.0314
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0118	0.3001	0.4402
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0113	0.2859	0.4193
Schistosoma mansoni	hypothetical protein	0.021	0.5786	0.5786
Trypanosoma cruzi	proteasome subunit alpha type-5, putative	0.014	0.3674	0.5387
Schistosoma mansoni	26s proteasome regulatory particle subunit	0.0033	0.0435	0.0435
Trichomonas vaginalis	regulatory particle non-ATPase, putative	0.0029	0.0314	0.0461
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0122	0.3115	0.4568
Leishmania major	proteasome alpha 1 subunit, putative	0.0141	0.3702	0.5429
Entamoeba histolytica	proteasome subunit alpha type 7, putative	0.0177	0.4797	0.7035
Plasmodium falciparum	26S protease regulatory subunit 6A, putative	0.0021	0.0053	0.0077
Echinococcus granulosus	26s protease regulatory subunit 6a	0.0021	0.0053	0.0053
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0129	0.3336	0.4892
Schistosoma mansoni	proteasome subunit beta 2 (T01 family)	0.0123	0.3165	0.3164
Trypanosoma cruzi	proteasome regulatory non-ATPase subunit 6, putative	0.0036	0.0498	0.0731
Entamoeba histolytica	proteasome subunit beta type 5 precursor, putative	0.0244	0.6819	1
Echinococcus granulosus	26S proteasome regulatory subunit N11	0.003	0.0319	0.0319
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0129	0.3349	0.4911
Toxoplasma gondii	peptidase, T1 family protein	0.0131	0.3384	0.4963
Trypanosoma cruzi	proteasome subunit beta type-5, putative	0.0244	0.6819	1
Trypanosoma brucei	proteasome beta 6 subunit	0.015	0.3981	0.5839
Echinococcus multilocularis	proteasome (prosome, macropain)	0.0244	0.6819	0.6819
Loa Loa (eye worm)	proteasome A-type and B-type family protein	0.0118	0.3001	0.4402
Giardia lamblia	Hypothetical protein	0.0036	0.0498	0.0731
Trichomonas vaginalis	26S proteasome non-ATPase regulatory subunit, putative	0.0028	0.0273	0.0401
Toxoplasma gondii	heat shock protein hslv, putative	0.0097	0.2377	0.3486
Brugia malayi	Proteasome A-type and B-type family protein	0.0244	0.6819	0.6819
Plasmodium falciparum	proteasome subunit alpha type-5, putative	0.014	0.3674	0.5387
Brugia malayi	Proteasome regulatory particle, non-atpase-like protein 6	0.0036	0.0498	0.0498
Echinococcus multilocularis	proteasome (prosome macropain) subunit alpha	0.0129	0.3336	0.3336
Schistosoma mansoni	subfamily T1A non-peptidase homologue (T01 family)	0.014	0.3674	0.3674

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL1946577

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1568660