Detailed information for compound 1568732

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 396.436 | Formula: C22H24N2O5
  • H donors: 0 H acceptors: 2 LogP: 4 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1cc(ccc1OC)C(=CC#N)c1ccc(c(c1)OC(=O)N(C)C)OC
  • InChi: 1S/C22H24N2O5/c1-6-28-20-13-15(7-9-18(20)26-4)17(11-12-23)16-8-10-19(27-5)21(14-16)29-22(25)24(2)3/h7-11,13-14H,6H2,1-5H3
  • InChiKey: CJDUNKLUUVJWIS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens phosphodiesterase 4D, cAMP-specific Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase 4C, putative Get druggable targets OG5_128242 All targets in OG5_128242
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein Get druggable targets OG5_128242 All targets in OG5_128242
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Cryptosporidium parvum membrane associated HD superfamily cyclic nucleotide phosphodiesterase domain containing protein Get druggable targets OG5_128242 All targets in OG5_128242
Neospora caninum cAMP-specific phosphodiesterase, putative Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase 4D, putative Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase, isoform F, putative Get druggable targets OG5_128242 All targets in OG5_128242
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum IPR002073,3'5'-cyclic nucleotide phosphodiesterase,domain-containing Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase 4D, putative Get druggable targets OG5_128242 All targets in OG5_128242
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.003 0.0042 0.008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0274
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0064 0.0477
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0042 0.026
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.0206 0.1262
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0005 0.0031
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0022 0.0064
Trypanosoma cruzi histone deacetylase, putative 0.0677 0.1632 1
Schistosoma mansoni protein kinase subunit beta 0.0015 0.0005 0.0016
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0096 0.0206 0.0712
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0166 0.1015
Toxoplasma gondii histone deacetylase HDAC2 0.0554 0.1332 0.2507
Leishmania major GTP-binding protein, putative 0.0022 0.0023 0.0144
Brugia malayi jmjC domain containing protein 0.0016 0.0008 0.0051
Plasmodium falciparum NIMA related kinase 4 0.0022 0.0025 0.0046
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Onchocerca volvulus 0.0034 0.0053 0.0433
Leishmania major chloride channel protein, putative 0.0021 0.0022 0.0135
Loa Loa (eye worm) hypothetical protein 0.0606 0.146 0.8942
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0021 0.0022 0.0022
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0259 0.0606 0.3713
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0014 0.0003 0.0018
Echinococcus multilocularis expressed conserved protein 0.0282 0.0661 0.0661
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0064 0.0477
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0093 0.027
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0238 0.0695
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0019 0.0114
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Trypanosoma brucei histone deacetylase 2 0.028 0.0658 0.4028
Echinococcus multilocularis cyclin dependent kinase 5 0.0047 0.0084 0.0084
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.005 0.0093 0.0568
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0021 0.0022 0.0474
Echinococcus multilocularis tar DNA binding protein 0.0128 0.0284 0.0284
Echinococcus granulosus hemicentin 1 0.0023 0.0027 0.0078
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0084 0.0516
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Onchocerca volvulus 0.0013 0 0.0002
Toxoplasma gondii patched family protein 0.0018 0.0014 0.0027
Brugia malayi CHE-14 protein 0.0129 0.0286 0.175
Brugia malayi AMP-binding enzyme family protein 0.0096 0.0206 0.1262
Toxoplasma gondii histone kinase SNF1, putative 0.005 0.0093 0.0175
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0015 0.0008 0.0022
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.0206 0.0384
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0045 0.013
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Echinococcus granulosus neuroligin 0.0034 0.0053 0.0154
Brugia malayi jmjC domain containing protein 0.0016 0.0008 0.0051
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.005 0.0093 0.0175
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0014 0.0003 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Echinococcus granulosus histone deacetylase 8 0.028 0.0658 0.1917
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.0238 0.227
Giardia lamblia Kinase, NEK 0.0022 0.0025 0.0168
Brugia malayi protein unc-22 0.0017 0.0011 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Echinococcus granulosus Immunoglobulin 0.0021 0.0022 0.0064
Loa Loa (eye worm) RNA binding protein 0.0128 0.0284 0.1739
Echinococcus granulosus phd:f box containing protein 0.0016 0.0008 0.0024
Brugia malayi Csnk2b protein 0.0037 0.0062 0.0377
Echinococcus granulosus neuroglian 0.0023 0.0027 0.0078
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Brugia malayi Disorganized muscle protein 1 0.0013 0 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0316
Loa Loa (eye worm) histone deacetylase 11 0.028 0.0658 0.4028
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0095 0.0278
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0323
Entamoeba histolytica deoxycytidyl transferase, putative 0.0108 0.0234 0.1759
Giardia lamblia Histone deacetylase 0.0554 0.1332 1
Leishmania major mitochondrial DNA polymerase beta 0.0307 0.0723 0.443
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0015 0.0008 0.0008
Loa Loa (eye worm) histone deacetylase 1 0.0554 0.1332 0.8158
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0323
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0016 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0584
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0014 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.0013 0 0.0001
Giardia lamblia DNA damage repair protein 0.0033 0.0052 0.0372
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0023 0.0027 0.0078
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0108 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0064 0.0237
Brugia malayi Immunoglobulin I-set domain containing protein 0.0528 0.1267 0.7761
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0135
Brugia malayi Histone deacetylase family protein 0.0677 0.1632 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0011 0.0068
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0096 0.0206 0.0783
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.0039 0.0039
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Toxoplasma gondii exonuclease III APE 0.0019 0.0016 0.003
Echinococcus granulosus titin 0.0013 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.02 0.0462 0.2831
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0326 0.1998
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.0238 0.0907
Plasmodium falciparum protein kinase 5 0.0047 0.0084 0.0158
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0021 0.0022 0.0135
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0023 0.0027 0.0027
Brugia malayi Myosin head containing protein 0.0018 0.0014 0.0087
Brugia malayi Patched protein homolog 1 0.0018 0.0014 0.0087
Leishmania major histone deacetylase, putative 0.0554 0.1332 0.8158
Loa Loa (eye worm) hypothetical protein 0.0121 0.0268 0.164
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Echinococcus multilocularis histone deacetylase 6 0.0677 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0135
Entamoeba histolytica protein kinase, putative 0.0176 0.0401 0.3009
Brugia malayi 6-phosphofructokinase 0.0109 0.0238 0.146
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0047 0.0084 0.0516
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Leishmania major hypothetical protein, conserved 0.0115 0.0253 0.1549
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0008 0.0008
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0328 0.0956
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0008 0.0008
Plasmodium vivax replication factor C subunit 1, putative 0.003 0.0042 0.008
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0176 0.0401 0.3009
Echinococcus multilocularis histone deacetylase 1 0.0554 0.1332 0.1332
Schistosoma mansoni hypothetical protein 0.0124 0.0274 0.0799
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0045 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0016
Schistosoma mansoni cell adhesion molecule 0.0013 0 0.0001
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0 0.0002
Trichomonas vaginalis ran, putative 0.0022 0.0023 0.0176
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0005 0.0005
Leishmania major serine/threonine-protein kinase, putative 0.0022 0.0025 0.015
Loa Loa (eye worm) hypothetical protein 0.0112 0.0244 0.1493
Brugia malayi DKFZp564C0469 protein 0.003 0.0042 0.026
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0239
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Schistosoma mansoni septate junction protein 0.0023 0.0027 0.0078
Trypanosoma brucei AIR9-like protein 0.0015 0.0005 0.0033
Schistosoma mansoni casein kinase II beta subunit 0.0037 0.0062 0.018
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0137 0.0516
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0096 0.0206 0.0783
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0045 0.0274
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0186 0.0426 0.2607
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Echinococcus granulosus tar DNA binding protein 0.0128 0.0284 0.0828
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0014 0.0003 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0042 0.0318
Echinococcus multilocularis tyrosine protein kinase otk 0.0023 0.0027 0.0027
Brugia malayi histone deacetylase 3 (HD3) 0.0554 0.1332 0.8158
Plasmodium falciparum histone deacetylase 2 0.0677 0.1632 0.3072
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Onchocerca volvulus 0.003 0.0042 0.0348
Echinococcus granulosus cpg binding protein 0.0062 0.0122 0.0354
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0027 0.0165
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0017 0.0049
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0176 0.0401 0.3009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0084 0.0244
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0047 0.0085 0.0159
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0021 0.0022 0.0022
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0005 0.0031
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0319 0.0752 0.4609
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0013 0 0.0001
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0021 0.0022 0.0076
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0135
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0021 0.0022 0.0076
Schistosoma mansoni histone deacetylase 4 5 0.0677 0.1632 0.4758
Toxoplasma gondii CBS family protein 0.0021 0.0022 0.0042
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0135
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0397 0.0944 0.5785
Giardia lamblia Kinase, CAMK CAMKL 0.005 0.0093 0.0681
Schistosoma mansoni cell adhesion molecule 0.0023 0.0027 0.0078
Echinococcus multilocularis dna polymerase kappa 0.0162 0.0367 0.0367
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0093 0.027
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0113 0.0694
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0042 0.0318
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0005 0.0015
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0304 0.0717 0.2091
Brugia malayi nuclear receptor NHR-67 0.0014 0.0005 0.0031
Giardia lamblia Hypothetical protein 0.0015 0.0008 0.004
Brugia malayi Muscleblind-like protein 0.0606 0.146 0.8942
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0022 0.0025 0.015
Schistosoma mansoni DNA polymerase IV / kappa 0.0033 0.0052 0.0151
Schistosoma mansoni cpg binding protein 0.0062 0.0122 0.0354
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) hypothetical protein 0.008 0.0166 0.1015
Plasmodium falciparum glycogen synthase kinase 3 0.0053 0.0099 0.0187
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0075 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0045 0.0274
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0137 0.0516
Trichomonas vaginalis histone deacetylase, putative 0.0554 0.1332 1
Onchocerca volvulus Putative titin 0.0013 0 0.0002
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0028 0.0039 0.0069
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0165
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0019 0.0019
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0072 0.0146 0.0553
Brugia malayi Pre-SET motif family protein 0.0031 0.0046 0.0285
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0059 0.0115 0.0216
Echinococcus multilocularis peroxidasin 0.0023 0.0027 0.0027
Schistosoma mansoni roundabout 0.0023 0.0027 0.0078
Brugia malayi hypothetical protein 0.003 0.0042 0.026
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0016 0.0098
Schistosoma mansoni titin 0.0017 0.0011 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0002 0.0016
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0015 0.0008 0.0047
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0039 0.0141
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0005 0.0005
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0045 0.0045
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0277 0.0808
Leishmania major hypothetical protein, conserved,leucine-rich repeat protein, putative 0.0015 0.0005 0.0033
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0021 0.0022 0.0135
Treponema pallidum DNA ligase (lig) 0.003 0.0042 0.0386
Loa Loa (eye worm) Csnk2b protein 0.0037 0.0062 0.0377
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0045 0.013
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) RecQ helicase 0.002 0.0019 0.0114
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0039 0.0239
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.026
Trypanosoma cruzi histone deacetylase, putative 0.0677 0.1632 1
Echinococcus multilocularis AMPK beta subunit 0.0115 0.0253 0.0253
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0246 0.0573 0.351
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0176 0.0401 0.1168
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0039 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0045 0.0274
Leishmania major DNA polymerase eta, putative 0.0133 0.0297 0.1821
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0021 0.0022 0.0076
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0096 0.018
Schistosoma mansoni nephrin related 0.0013 0 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0047 0.0084 0.0516
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.0039 0.0114
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0014 0.0003 0.0008
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0016 0.012
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0436 0.1042 0.7824
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0045 0.013
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0186 0.0426 0.2607
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0096 0.018
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0554 0.1332 1
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0117 0.0257 0.0909
Brugia malayi RNA, U transporter 1 0.0085 0.0178 0.1091
Echinococcus multilocularis dna polymerase eta 0.0133 0.0297 0.0297
Onchocerca volvulus 0.0034 0.0053 0.0433
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Plasmodium falciparum flap endonuclease 1 0.0053 0.0101 0.019
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0028 0.0039 0.0069
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0039 0.0239
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0003 0.0018
Mycobacterium tuberculosis Carboxylesterase LipT 0.0034 0.0053 0.0194
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0023 0.0068
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0053 0.0099 0.029
Loa Loa (eye worm) CAMK protein kinase 0.0017 0.0011 0.0068
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0112 0.0244 0.0711
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Echinococcus multilocularis importin subunit beta 1 0.003 0.0043 0.0043
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Brugia malayi Thioredoxin reductase 0.0038 0.0064 0.0392
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0005 0.0041
Schistosoma mansoni titin 0.0013 0 0.0001
Echinococcus granulosus leucine rich repeat containing protein 4 0.0013 0 0.0001
Schistosoma mansoni hypothetical protein 0.0013 0 0.0001
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0008 0.0051
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0046 0.0135
Trypanosoma brucei histone deacetylase 3 0.0677 0.1632 1
Trypanosoma cruzi histone deacetylase 1, putative 0.0554 0.1332 0.8158
Brugia malayi Myb-like DNA-binding domain containing protein 0.0013 0 0.0002
Schistosoma mansoni hypothetical protein 0.008 0.0166 0.0483
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0115 0.0115
Schistosoma mansoni ets-related 0.0221 0.0511 0.1491
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0016 0.012
Trichomonas vaginalis flap endonuclease-1, putative 0.0053 0.0101 0.0756
Trypanosoma brucei DNA polymerase IV, putative 0.0148 0.0334 0.2045
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0064 0.0392
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.0008 0.0047
Schistosoma mansoni hypothetical protein 0.0013 0 0.0001
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0039 0.0293
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0062 0.0463
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0328 0.2009
Brugia malayi glutaminase DH11.1 0.0549 0.1319 0.8082
Schistosoma mansoni hypothetical protein 0.0013 0 0.0001
Schistosoma mansoni protein kinase 0.0176 0.0401 0.1168
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0014 0.0003 0.0018
Leishmania major chloride channel protein, putative 0.0021 0.0022 0.0135
Trichomonas vaginalis spcc417.12 protein, putative 0.0034 0.0053 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0042 0.0318
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0042 0.026
Loa Loa (eye worm) hypothetical protein 0.0096 0.0206 0.1262
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0029 0.0218
Loa Loa (eye worm) hypothetical protein 0.0152 0.0343 0.2102
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.0039 0.0073
Echinococcus granulosus neuroglian 0.0034 0.0053 0.0154
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0005 0.0015
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0023 0.0027 0.0027
Loa Loa (eye worm) acetyltransferase 0.0146 0.0328 0.2009
Schistosoma mansoni histone deacetylase 1 2 3 0.028 0.0658 0.1917
Loa Loa (eye worm) hypothetical protein 0.0042 0.0073 0.045
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0115 0.0253 0.1549
Mycobacterium ulcerans cystathionine beta-synthase 0.0021 0.0022 0.0037
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0112 0.0244 0.0244
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0053 0.0154
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0015 0.0008 0.0022
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0123 0.0754
Loa Loa (eye worm) histone deacetylase 7A 0.0677 0.1632 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0135
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0023 0.0144
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0238 0.1789
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0028 0.0039 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0436 0.1042 0.7824
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0039 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0042 0.0318
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0021 0.0022 0.0135
Chlamydia trachomatis CBS domain-containing protein 0.0021 0.0022 0.0037
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.003 0.0042 0.0079
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0117 0.0257 0.0978
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0039 0.0239
Echinococcus granulosus titin 0.0017 0.0011 0.0032
Brugia malayi glutathione reductase 0.0038 0.0064 0.0392
Loa Loa (eye worm) glutaminase 0.0549 0.1319 0.8082
Leishmania major cAMP-specific phosphodiesterase, putative 0.0014 0.0003 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0003 0.0018
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.03 0.0707 0.2654
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0014 0.0003 0.0018
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Leishmania major DNA polymerase eta, putative 0.0059 0.0115 0.0702
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0022 0.0025 0.015
Echinococcus granulosus Niemann Pick C1 protein 0.0428 0.1022 0.2979
Brugia malayi cell division control protein 2 homolog 0.0047 0.0084 0.0516
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0027 0.0165
Plasmodium vivax histone deacetylase, putative 0.028 0.0658 0.1238
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0786 0.1901 0.7297
Brugia malayi hypothetical protein 0.0152 0.0343 0.2102
Echinococcus multilocularis roundabout 2 0.0045 0.0079 0.0079
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0331 0.0784 0.48
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0075 0.0563
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0027 0.0165
Plasmodium falciparum chorismate synthase 0.2175 0.5313 1
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0013 0 0.0001
Brugia malayi Flap endonuclease-1 0.0053 0.0101 0.0617
Trypanosoma cruzi DNA damage repair protein, putative 0.0033 0.0052 0.0317
Schistosoma mansoni cell adhesion molecule 0.0023 0.0027 0.0078
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0022 0.0135
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.0062 0.0122 0.0354
Trypanosoma cruzi histone deacetylase 1, putative 0.0554 0.1332 0.8158
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Brugia malayi Carboxylesterase family protein 0.02 0.0462 0.2831
Toxoplasma gondii NEK kinase 0.0022 0.0025 0.0046
Schistosoma mansoni alkaline phosphatase 0.0164 0.0372 0.1083
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0068 0.0137 0.0257
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0 0.0002
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0018
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0112 0.0244 0.0459
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0014 0.0003 0.0008
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0186 0.0426 0.2607
Entamoeba histolytica hypothetical protein 0.0037 0.0059 0.0446
Leishmania major guanosine monophosphate reductase 0.0021 0.0022 0.0135
Mycobacterium tuberculosis Probable oxidoreductase 0.0097 0.0209 0.0794
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0176 0.0401 0.3009
Echinococcus granulosus roundabout 2 0.0023 0.0027 0.0078
Echinococcus multilocularis dnaJ subfamily B 0.0834 0.2018 0.2018
Schistosoma mansoni histone deacetylase hda2 0.028 0.0658 0.1917
Onchocerca volvulus 0.0017 0.0011 0.009
Trypanosoma cruzi leucine rich repeat protein, putative 0.0015 0.0005 0.0033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Echinococcus multilocularis lachesin 0.0023 0.0027 0.0027
Toxoplasma gondii NEK kinase 0.0022 0.0025 0.0046
Brugia malayi Fli-1 protein 0.0221 0.0511 0.3133
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0 0.0002
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0042 0.0079
Loa Loa (eye worm) histone deacetylase 3 0.0554 0.1332 0.8158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0002 0.0014
Echinococcus granulosus nibrin 0.003 0.0042 0.0124
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0 0.0002
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0 0.0002
Onchocerca volvulus Glucosylceramidase homolog 0.017 0.0387 0.3177
Trypanosoma cruzi cdc2-related kinase 3 0.0047 0.0084 0.0516
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0005
Toxoplasma gondii patched family protein 0.0018 0.0014 0.0027
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0034 0.0053 0.0396
Plasmodium falciparum phosphodiesterase gamma, putative 0.0014 0.0003 0.0005
Loa Loa (eye worm) PDE1B protein 0.0014 0.0003 0.0018
Onchocerca volvulus 0.0034 0.0053 0.0433
Onchocerca volvulus 0.0013 0 0.0002
Mycobacterium tuberculosis Conserved protein 0.0021 0.0022 0.0076
Brugia malayi ancient conserved domain protein 2 0.0021 0.0022 0.0135
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0002 0.0004
Leishmania major protein kinase, putative 0.0022 0.0025 0.015
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0046 0.0087
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0096 0.0587
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Loa Loa (eye worm) AUR protein kinase 0.0176 0.0401 0.2455
Trypanosoma cruzi DNA polymerase eta, putative 0.0133 0.0297 0.1821
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0097 0.0209 0.0794
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0045 0.0045
Entamoeba histolytica hypothetical protein 0.0037 0.0059 0.0446
Echinococcus multilocularis hemicentin 1 0.0023 0.0027 0.0027
Entamoeba histolytica protein kinase domain containing protein 0.0186 0.0426 0.3196
Toxoplasma gondii hypothetical protein 0.0049 0.0091 0.0171
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0045 0.013
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0284 0.0828
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0014 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0045 0.0274
Echinococcus multilocularis hemicentin 1 0.0023 0.0027 0.0027
Toxoplasma gondii hypothetical protein 0.0015 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0452 0.1079 0.661
Brugia malayi hypothetical protein 0.0018 0.0014 0.0087
Onchocerca volvulus 0.0053 0.0099 0.0816
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0323
Echinococcus granulosus insulin growth factor binding 0.0013 0 0.0001
Echinococcus granulosus dual specificity 0.0186 0.0426 0.1241
Plasmodium falciparum glutathione reductase 0.0038 0.0064 0.012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0135
Loa Loa (eye worm) hypothetical protein 0.0129 0.0286 0.175
Schistosoma mansoni neuroligin 3 (S09 family) 0.0034 0.0053 0.0154
Schistosoma mansoni hypothetical protein 0.0013 0 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0284 0.0828
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0005 0.0031
Chlamydia trachomatis Mg++ transporter 0.0021 0.0022 0.0037
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.0008 0.0047
Brugia malayi hypothetical protein 0.0018 0.0014 0.0087
Brugia malayi nuclear hormone receptor 0.0014 0.0005 0.0031
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0002 0.0014
Onchocerca volvulus 0.0152 0.0343 0.2816
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0017 0.0048
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0045 0.0274
Brugia malayi hypothetical protein 0.0021 0.0022 0.0135
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0002 0.0014
Echinococcus granulosus Niemann Pick C1 protein 0.03 0.0706 0.2058
Loa Loa (eye worm) oxidoreductase 0.0028 0.0039 0.0239
Leishmania major hypothetical protein, conserved 0.0014 0.0003 0.0018
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0062 0.0116
Onchocerca volvulus 0.0034 0.0053 0.0433
Leishmania major inosine-5-monophosphate dehydrogenase 0.0021 0.0022 0.0135
Echinococcus multilocularis cpg binding protein 0.0062 0.0122 0.0122
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0023 0.0144
Brugia malayi jmjC domain containing protein 0.0016 0.0008 0.0051
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0005 0.0031
Onchocerca volvulus 0.0034 0.0053 0.0433
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0148 0.0431
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0019 0.0114
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0005 0.0031
Brugia malayi histone deacetylase 1 (HD1) 0.0554 0.1332 0.8158
Giardia lamblia Kinase, CMGC GSK 0.0053 0.0099 0.0732
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0274
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0052 0.0317
Loa Loa (eye worm) carboxylesterase 0.0034 0.0053 0.0323
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Brugia malayi Prion-like- 0.0013 0 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0039 0.0069
Loa Loa (eye worm) hypothetical protein 0.0181 0.0415 0.2541
Loa Loa (eye worm) hypothetical protein 0.0045 0.0079 0.0486
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.0039 0.0239
Leishmania major trypanothione reductase 0.0038 0.0064 0.0392
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0013 0 0.0001
Schistosoma mansoni apoptosis regulator bax 0.0083 0.0174 0.0508
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0323
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Onchocerca volvulus 0.0028 0.0039 0.032
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0021 0.0022 0.0064
Loa Loa (eye worm) acetylcholinesterase 1 0.02 0.0462 0.2831
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0014 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0573 0.167
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0436 0.1042 0.7824
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0096 0.0206 0.0384
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0166 0.0483
Mycobacterium tuberculosis Probable reductase 0.0088 0.0185 0.0702
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0165
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0135
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0083 0.0174 0.0508
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0022 0.0135
Toxoplasma gondii aurora kinase 0.0176 0.0401 0.0754
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0328 0.0328
Brugia malayi Leucine Rich Repeat family protein 0.0013 0 0.0002
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0019 0.0114
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.026
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0005 0.0031
Brugia malayi steroid hormone receptor 0.0031 0.0045 0.0274
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0028 0.0039 0.0141
Trypanosoma brucei DNA polymerase IV, putative 0.0162 0.0367 0.2246
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0025 0.0184
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0045 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0013 0 0.0002
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0039 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0093 0.027
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Brugia malayi Latrophilin receptor protein 2 0.008 0.0166 0.1015
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0014 0.0003 0.0003
Schistosoma mansoni acetylcholinesterase 0.0034 0.0053 0.0154
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0064 0.0185
Trypanosoma brucei cdc2-related kinase 3 0.0047 0.0084 0.0516
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0015 0.0008 0.0057
Entamoeba histolytica protein kinase , putative 0.0176 0.0401 0.3009
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0096 0.0206 0.0384
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0088 0.0185 0.0702
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.026
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0387 0.2908
Schistosoma mansoni hypothetical protein 0.0124 0.0274 0.0799
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0098 0.021 0.0613
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0115 0.0253 0.1549
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Echinococcus granulosus acetylcholinesterase 0.02 0.0462 0.1347
Onchocerca volvulus Protein patched homolog 0.0018 0.0014 0.0116
Schistosoma mansoni DNA helicase recq1 0.002 0.0019 0.0054
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0016 0.0104
Loa Loa (eye worm) glutathione reductase 0.0038 0.0064 0.0392
Trypanosoma brucei DNA polymerase IV, putative 0.0162 0.0367 0.2246
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.0723 0.443
Brugia malayi hypothetical protein 0.0014 0.0005 0.0031
Loa Loa (eye worm) animal heme peroxidase 0.0013 0 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.0008 0.0057
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.0008 0.0047
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0042 0.0079
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0029 0.0218
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0016 0.003
Treponema pallidum P26 0.0015 0.0005 0.003
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0041 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0267 0.1636
Echinococcus multilocularis tumor protein p63 0.035 0.0829 0.0829
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0045 0.0274
Brugia malayi Prion-like- 0.0023 0.0027 0.0165
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0062 0.0463
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0083 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0135
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.007 0.0142 0.0867
Echinococcus multilocularis acetylcholinesterase 0.02 0.0462 0.0462
Schistosoma mansoni DNA polymerase eta 0.0133 0.0297 0.0866
Echinococcus multilocularis cyclin dependent kinase 0.0047 0.0084 0.0084
Schistosoma mansoni patched 1 0.0129 0.0286 0.0832
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0135
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0042 0.026
Echinococcus granulosus GPCR family 2 0.008 0.0166 0.0483
Chlamydia trachomatis chorismate synthase 0.2175 0.5313 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0021 0.0022 0.0474
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0002 0.0004
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0014 0.0003 0.0008
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0123 0.0359
Brugia malayi Carboxylesterase family protein 0.0034 0.0053 0.0323
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0034 0.0053 0.0194
Trypanosoma cruzi FHA domain containing protein, putative 0.003 0.0042 0.026
Echinococcus multilocularis histone deacetylase 6 0.0677 0.1632 0.1632
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0307 0.0723 0.443
Echinococcus granulosus expressed conserved protein 0.0282 0.0661 0.1928
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0025 0.0071
Brugia malayi MH2 domain containing protein 0.012 0.0265 0.1622
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.0487 0.2985
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0389
Schistosoma mansoni nuclear receptor 0.0014 0.0005 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0008 0.0024
Brugia malayi ecdysteroid receptor 0.0031 0.0045 0.0274
Brugia malayi Calcitonin receptor-like protein seb-1 0.0252 0.059 0.3612
Onchocerca volvulus 0.0013 0 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0185 0.1133
Toxoplasma gondii histone deacetylase HDAC4 0.028 0.0658 0.1238
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0021 0.0022 0.0474
Brugia malayi Animal haem peroxidase family protein 0.0013 0 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0045 0.0274
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0018
Loa Loa (eye worm) patched family protein 0.0018 0.0014 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0016
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Onchocerca volvulus 0.0013 0 0.0002
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0121 0.0267 0.1636
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0062 0.0377
Echinococcus granulosus casein kinase ii subunit beta 0.0037 0.0062 0.018
Brugia malayi hypothetical protein 0.0037 0.0059 0.0364
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0083 0.0174 0.0174
Echinococcus granulosus acetylcholinesterase 0.02 0.0462 0.1347
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0033 0.0052 0.0097
Echinococcus granulosus AMPK beta subunit 0.0115 0.0253 0.0737
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Loa Loa (eye worm) patched family protein 0.0018 0.0014 0.0087
Schistosoma mansoni chloride channel protein 0.0021 0.0022 0.0064
Brugia malayi putative serine/threonine kinase SADA gamma 0.005 0.0093 0.0568
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0062 0.0116
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0115 0.0253 0.1885
Echinococcus granulosus muscleblind protein 0.0606 0.146 0.4255
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0099 0.0747
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0033
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0084 0.0632
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0011 0.0032
Loa Loa (eye worm) patched family protein 0.0018 0.0014 0.0087
Mycobacterium ulcerans chorismate synthase 0.2175 0.5313 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0096 0.018
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.0039 0.0073
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0014 0.0003 0.0008
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0065 0.0065
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0099 0.0747
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0022 0.0135
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0016 0.0047
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0052 0.0317
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0252 0.059 0.3612
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0117 0.0257 0.0479
Echinococcus multilocularis microtubule associated protein 2 0.1409 0.3431 0.3431
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0237 0.0553 0.0553
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0057
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0002 0.0004
Brugia malayi 6-phosphofructokinase 0.0109 0.0238 0.1461
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0014 0.0003 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0045 0.013
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Schistosoma mansoni topbp1 0.003 0.0042 0.0124
Mycobacterium ulcerans DNA polymerase IV 0.0162 0.0367 0.0686
Schistosoma mansoni hypothetical protein 0.0083 0.0174 0.0508
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0028 0.0038 0.023
Echinococcus granulosus cyclin dependent kinase 0.0047 0.0084 0.0245
Entamoeba histolytica protein kinase, putative 0.0053 0.0099 0.0747
Plasmodium falciparum replication factor C subunit 1, putative 0.003 0.0042 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0185 0.1133
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.0206 0.0384
Echinococcus granulosus alkaline phosphatase 0.0164 0.0372 0.1083
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0326 0.1998
Echinococcus granulosus replication factor c subunit 1 0.003 0.0042 0.0124
Schistosoma mansoni terminal deoxycytidyl transferase 0.0108 0.0234 0.0683
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0254 0.0592 0.1727
Trichomonas vaginalis histone deacetylase, putative 0.0554 0.1332 1
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0183 0.042 0.3446
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0014 0.0003 0.0008
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0025 0.015
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0023 0.0027 0.0027
Echinococcus granulosus histone deacetylase 6 0.0677 0.1632 0.4758
Onchocerca volvulus 0.0018 0.0014 0.0116
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0032 0.0049 0.0142
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0022 0.0135
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0023 0.0027 0.0078
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0015 0.0008 0.0022
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0005 0.0015
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0014 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0121 0.0268 0.164
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0083 0.0174 0.1068
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Loa Loa (eye worm) hypothetical protein 0.014 0.0314 0.1925
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0084 0.0244
Mycobacterium ulcerans hypothetical protein 0.0021 0.0022 0.0037
Trypanosoma cruzi DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0045 0.0045
Echinococcus granulosus para nitrobenzyl esterase 0.0034 0.0053 0.0154
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.0366 0.14
Entamoeba histolytica acyl-CoA synthetase, putative 0.0096 0.0206 0.1547
Brugia malayi hypothetical protein 0.0034 0.0053 0.0323
Chlamydia trachomatis DNA ligase 0.003 0.0042 0.0076
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0062 0.0116
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Brugia malayi topoisomerase 0.003 0.0042 0.026
Echinococcus granulosus titin 0.0013 0 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0002 0.0016
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0164 0.0372 0.0372
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0045 0.013
Mycobacterium tuberculosis Conserved protein 0.0021 0.0022 0.0076
Echinococcus granulosus defective proboscis extension response 0.0021 0.0022 0.0064
Brugia malayi intracellular kinase 0.0053 0.0099 0.0609
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0084 0.0616
Echinococcus granulosus down syndrome cell adhesion 0.0013 0 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0133 0.0297 0.1821
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0013 0.0002 0.0001
Entamoeba histolytica Ran family GTPase 0.0022 0.0023 0.0176
Plasmodium falciparum importin beta, putative 0.003 0.0043 0.0081
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0075 0.0141
Echinococcus multilocularis bloom syndrome protein 0.002 0.0019 0.0019
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0123 0.0359
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.0039 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0027 0.0165
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0084 0.0512
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0164 0.0372 0.1083
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0129 0.0286 0.175
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Onchocerca volvulus Histone deacetylase 10 homolog 0.028 0.0658 0.5396
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0016 0.0053
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.041 0.3076
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0015 0.0008 0.0057
Entamoeba histolytica hypothetical protein 0.0024 0.0029 0.0218
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Loa Loa (eye worm) chloride channel 3 0.0021 0.0022 0.0135
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0002 0.0017
Leishmania major hypothetical protein, conserved 0.0014 0.0003 0.0018
Loa Loa (eye worm) histone deacetylase 0.0677 0.1632 1
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0022 0.0064
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0064 0.0064
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0254 0.0592 0.1727
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0027 0.0165
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0015 0.0008 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Entamoeba histolytica hypothetical protein 0.0186 0.0426 0.3196
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0064 0.0064
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0019 0.0054
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) runx1 0.0057 0.0109 0.0666
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0274
Echinococcus granulosus nephrin 0.0013 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0173 0.0393 0.241
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0045 0.013
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0097 0.0209 0.0794
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0238 0.1789
Schistosoma mansoni glutaminase 0.0549 0.1319 0.3845
Echinococcus granulosus histone deacetylase 6 0.0689 0.1663 0.4847
Loa Loa (eye worm) hypothetical protein 0.0554 0.1332 0.8158
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0009 0.0009
Leishmania major DNA damage repair protein, putative 0.0033 0.0052 0.0317
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0016 0.0099
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0045 0.013
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0029 0.0104
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.005 0.0093 0.0568
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Onchocerca volvulus 0.0018 0.0014 0.0116
Echinococcus multilocularis muscleblind protein 0.0606 0.146 0.146
Onchocerca volvulus 0.0028 0.0039 0.032
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0019 0.0035
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.0008 0.0047
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0083 0.0174 0.1068
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0042 0.0075
Schistosoma mansoni hypothetical protein 0.0083 0.0174 0.0508
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0014 0.0027
Onchocerca volvulus 0.0014 0.0005 0.0041
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0014 0.0003 0.0018
Trichomonas vaginalis DNA polymerase eta, putative 0.0162 0.0367 0.2753
Echinococcus multilocularis roundabout 2 0.0023 0.0027 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0387 0.2908
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) hypothetical protein 0.0261 0.0611 0.3743
Entamoeba histolytica protein kinase, putative 0.0176 0.0401 0.3009
Loa Loa (eye worm) AUR protein kinase 0.0176 0.0401 0.2455
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0238 0.1789
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0021 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.0284 0.1739
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0005 0.0031
Brugia malayi Prion-like- 0.0013 0 0.0002
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0005 0.0015
Loa Loa (eye worm) AUR protein kinase 0.0176 0.0401 0.2455
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0015 0.0008 0.0022
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0015 0.0008 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0039 0.0069
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0014 0.0003 0.0008
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0021 0.0022 0.0076
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0037 0.0062 0.0116
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0064 0.0461
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0176 0.0401 0.0401
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0003 0.0018
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0075 0.0462
Echinococcus granulosus lachesin 0.0023 0.0027 0.0078
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.0206 0.1262
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Schistosoma mansoni titin 0.0013 0 0.0001
Echinococcus multilocularis histone deacetylase 0.0677 0.1632 0.1632
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0164 0.0372 0.0372
Echinococcus multilocularis histone deacetylase 6 0.0689 0.1663 0.1663
Schistosoma mansoni nuclear receptor 0.0014 0.0005 0.0015
Brugia malayi RNA binding protein 0.0128 0.0284 0.1739
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Plasmodium falciparum glutathione reductase 0.0013 0.0002 0.0004
Echinococcus multilocularis protein patched 0.0129 0.0286 0.0286
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0042 0.0384
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0064 0.0392
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0039 0.0239
Entamoeba histolytica Flap nuclease, putative 0.0053 0.0101 0.0756
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0554 0.1332 1
Trichomonas vaginalis helicase, putative 0.0013 0.0002 0.0016
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0022 0.0135
Toxoplasma gondii propionate-CoA ligase 0.0028 0.0039 0.0073
Treponema pallidum fructose-bisphosphate aldolase 0.0436 0.1042 1
Trypanosoma cruzi SNF1-related protein kinases, putative 0.005 0.0093 0.0568
Toxoplasma gondii ATPase, AAA family protein 0.003 0.0042 0.008
Echinococcus multilocularis Protein lozenge 0.0057 0.0109 0.0109
Chlamydia trachomatis dehyroquinate synthase 0.0117 0.0257 0.0479
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.0008 0.0057
Echinococcus granulosus flap endonuclease 1 0.0053 0.0101 0.0294
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0606 0.4551
Loa Loa (eye worm) TAR-binding protein 0.0128 0.0284 0.1739
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0135
Brugia malayi Histone deacetylase 1 0.0554 0.1332 0.8158
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0084 0.0244
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0014 0.0003 0.0003
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0045 0.0367
Schistosoma mansoni protein kinase subunit beta 0.0062 0.0122 0.0354
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.026
Schistosoma mansoni gliotactin 0.0034 0.0053 0.0154
Brugia malayi hypothetical protein 0.0014 0.0005 0.0031
Loa Loa (eye worm) hypothetical protein 0.0181 0.0415 0.2541
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.041 0.3076
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0045 0.013
Schistosoma mansoni vesicular amine transporter 0.0021 0.0022 0.0064
Schistosoma mansoni microtubule-associated protein tau 0.1409 0.3431 1
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0387 0.2908
Loa Loa (eye worm) hypothetical protein 0.0032 0.0049 0.0297
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0075 0.0563
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0022 0.0135
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0034 0.0053 0.0194
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0064 0.0185
Brugia malayi Pre-SET motif family protein 0.0211 0.0487 0.2985
Brugia malayi phosphofructokinase 0.0109 0.0238 0.146
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.0021 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0896
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0019 0.0019
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0002 0.0014
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0786 0.1901 0.7276
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Echinococcus granulosus peroxidasin 0.0023 0.0027 0.0078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0016 0.0133
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0265 0.1622
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0005 0.0015
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0016 0.0009 0.0009
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0021 0.0022 0.0064
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0238 0.0695
Plasmodium falciparum phosphodiesterase delta, putative 0.0014 0.0003 0.0005
Mycobacterium ulcerans DNA polymerase IV 0.0162 0.0367 0.0686
Brugia malayi Ets-domain containing protein 0.0073 0.0148 0.0907
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Echinococcus multilocularis histone deacetylase 3 0.0554 0.1332 0.1332
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0043 0.0263
Treponema pallidum hemolysin (tlyC) 0.0021 0.0022 0.0191
Brugia malayi nuclear hormone receptor 0.0031 0.0045 0.0274
Schistosoma mansoni nephrin 0.0023 0.0027 0.0078
Brugia malayi tailless protein 0.0014 0.0005 0.0031
Brugia malayi Carboxylesterase family protein 0.0034 0.0053 0.0323
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0002 0.0004
Onchocerca volvulus 0.0051 0.0095 0.0782
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0121 0.0266 0.0776
Treponema pallidum Mg2+ transport protein (mgtE) 0.0021 0.0022 0.0191
Onchocerca volvulus 0.0013 0 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0002 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0039 0.0069
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0042 0.0316
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0027 0.0165
Schistosoma mansoni titin 0.0013 0 0.0001
Plasmodium vivax chorismate synthase 0.2175 0.5313 1
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0042 0.0318
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0062 0.0116
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0016 0.033
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Schistosoma mansoni protein kinase subunit beta 0.0115 0.0253 0.0737
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0014 0.0003 0.0008
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0008 0.0016
Trichomonas vaginalis replication factor C large subunit, putative 0.003 0.0042 0.0318
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0021 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0185 0.1133
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0065 0.019
Echinococcus multilocularis carboxylesterase 5A 0.02 0.0462 0.0462
Brugia malayi CLC chloride channel protein 0.0021 0.0022 0.0135
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0606 0.4551
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.0008 0.0047
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0896
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0099 0.0747
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0062 0.0506
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0042 0.0079
Schistosoma mansoni hypothetical protein 0.008 0.0166 0.0483
Loa Loa (eye worm) hypothetical protein 0.0096 0.0206 0.1262
Loa Loa (eye worm) TK protein kinase 0.0016 0.0009 0.0053
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0014 0.0003 0.0018
Schistosoma mansoni DNA ligase IV 0.003 0.0042 0.0124
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0053 0.0099 0.0609
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0042 0.0318
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0016 0.0016
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0786 0.1901 0.3575
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0084 0.0632
Brugia malayi hypothetical protein 0.0033 0.0051 0.0313
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0096 0.0587
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0014 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0039 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0045 0.0274
Loa Loa (eye worm) apoptosis regulator protein 0.0083 0.0174 0.1068
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0045 0.013
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.003 0.0042 0.0076
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0238 0.1789
Echinococcus granulosus tumor protein p63 0.035 0.0829 0.2416
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Trypanosoma brucei histone deacetylase, putative 0.0677 0.1632 1
Leishmania major DNA polymerase kappa, putative 0.0121 0.0267 0.1636
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.0238 0.146
Brugia malayi hypothetical protein 0.0046 0.0082 0.0502
Entamoeba histolytica hypothetical protein 0.003 0.0042 0.0318
Loa Loa (eye worm) hypothetical protein 0.0031 0.0046 0.0285
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0008 0.0024
Schistosoma mansoni titin 0.0013 0 0.0001
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0022 0.0135
Echinococcus multilocularis sterol regulatory element binding protein 0.0129 0.0286 0.0286
Toxoplasma gondii chorismate synthase, putative 0.2175 0.5313 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0008 0.0023
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0045 0.013
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0075 0.0218
Brugia malayi AMP-binding enzyme family protein 0.0096 0.0206 0.1262
Echinococcus multilocularis histone deacetylase 8 0.028 0.0658 0.0658
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.0039 0.0066
Echinococcus multilocularis serine:threonine kinase SAD 1 0.005 0.0093 0.0093
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0115 0.0253 0.1549
Loa Loa (eye worm) carboxylesterase 0.02 0.0462 0.2831
Loa Loa (eye worm) hypothetical protein 0.0046 0.0082 0.0502
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0017 0.0017
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0014 0.0003 0.0018
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0044
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) carboxylesterase 0.0034 0.0053 0.0323
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0096 0.0206 0.0712
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0112 0.0244 0.0711
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0025 0.0184
Schistosoma mansoni cell adhesion molecule 0.0023 0.0027 0.0078
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0259 0.0606 0.3713
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0246 0.0573 0.167
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0014 0.0003 0.0008
Giardia lamblia hypothetical protein 0.0014 0.0003 0.0005
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0039 0.0069
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0039 0.0141
Loa Loa (eye worm) disorganized muscle protein 1 0.0013 0 0.0002
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0005 0.0015
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0064 0.012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.005 0.0093 0.0568
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0164 0.0372 0.1083
Entamoeba histolytica serine/threonine protein kinase, putative 0.005 0.0093 0.0697
Toxoplasma gondii patched family protein 0.0018 0.0014 0.0027
Trypanosoma brucei unspecified product 0.0148 0.0334 0.2045
Onchocerca volvulus Netrin receptor homolog 0.0013 0 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0387 0.2908
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0039 0.0239
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0025 0.015
Brugia malayi serine/threonine kinase 12 0.0176 0.0401 0.2455
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0014 0.0003 0.0018
Entamoeba histolytica hypothetical protein 0.0037 0.0059 0.0446
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0176 0.0401 0.3009
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0005
Giardia lamblia Replication factor C, subunit 1 0.003 0.0042 0.0302
Brugia malayi latrophilin 2 splice variant baaae 0.0173 0.0393 0.241
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0045 0.013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Trypanosoma cruzi GMP reductase 0.0021 0.0022 0.0135
Toxoplasma gondii patched family protein 0.0018 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0016 0.0098
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0021 0.0022 0.0022
Entamoeba histolytica protein kinase, putative 0.0186 0.0426 0.3196
Trypanosoma brucei aurora B kinase 0.0176 0.0401 0.2455
Loa Loa (eye worm) hypothetical protein 0.0133 0.0297 0.1821
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0027 0.0165
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0019 0.0139
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0019 0.0114
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0148 0.0148
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0401 0.1168
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0045 0.0274
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0316
Leishmania major hypothetical protein, conserved 0.0051 0.0096 0.0587
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0015 0.0008 0.0047
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0183 0.042 0.2573
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0316
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0184 0.1127
Schistosoma mansoni hypothetical protein 0.0173 0.0393 0.1147
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.0286 0.2144
Loa Loa (eye worm) hypothetical protein 0.005 0.0093 0.0568
Trypanosoma cruzi NIMA-related kinase, putative 0.0022 0.0025 0.015
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0039 0.0239
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0064 0.0389
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0002 0.0014
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0026 0.0026
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0045 0.013
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0238 0.146
Onchocerca volvulus 0.0059 0.0113 0.093
Trichomonas vaginalis set domain proteins, putative 0.024 0.0558 0.4193
Schistosoma mansoni ran 0.0022 0.0023 0.0068
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0018
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0064 0.0389
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0013 0 0.0001
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0016 0.0098
Toxoplasma gondii CBS domain-containing protein 0.0021 0.0022 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0009 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0022
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0039 0.0069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0045 0.0274
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0274
Schistosoma mansoni BC026374 protein (S09 family) 0.0034 0.0053 0.0154
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0008 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0003 0.0018
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0084 0.0244
Schistosoma mansoni neuroglian 0.0023 0.0027 0.0078
Plasmodium vivax JmjC domain containing protein 0.0016 0.0008 0.0016
Onchocerca volvulus 0.0031 0.0045 0.0367
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0052 0.0317
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0043 0.0081
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0009 0.0027
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0165
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0064 0.0185
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.0022 0.0149
Schistosoma mansoni hypothetical protein 0.0083 0.0174 0.0508
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0014 0.0003 0.0008
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0528 0.1267 0.7761
Trypanosoma cruzi histone deacetylase, putative 0.028 0.0658 0.4028
Loa Loa (eye worm) hypothetical protein 0.0606 0.146 0.8942
Schistosoma mansoni hypothetical protein 0.008 0.0166 0.0483
Plasmodium falciparum serine/threonine protein kinase KIN 0.005 0.0093 0.0175
Plasmodium vivax histone deacetylase 1, putative 0.0554 0.1332 0.2507
Echinococcus granulosus BC026374 protein S09 family 0.0034 0.0053 0.0154
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0016
Trypanosoma cruzi histone deacetylase, putative 0.0677 0.1632 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.03 0.0706 0.0706
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0045 0.013
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0019 0.0114
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0075 0.0462
Leishmania major histone deacetylase, putative 0.0554 0.1332 0.8158
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0046 0.0135
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.0008 0.0057
Entamoeba histolytica serine/threonine protein kinase, putative 0.0022 0.0025 0.0184
Brugia malayi hypothetical protein 0.0016 0.0009 0.0057
Plasmodium vivax flap endonuclease 1, putative 0.0053 0.0101 0.019
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0015 0.0008 0.0008
Echinococcus granulosus Protein patched homolog 1 0.0129 0.0286 0.0832
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Giardia lamblia Kinase, CMGC GSK 0.0053 0.0099 0.0732
Brugia malayi ecdysone receptor 0.0014 0.0005 0.0031
Echinococcus multilocularis Immunoglobulin 0.0021 0.0022 0.0022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0002 0.0014
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.03 0.0707 0.1331
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0896
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0053 0.0101 0.0617
Mycobacterium tuberculosis Conserved protein 0.0021 0.0022 0.0076
Onchocerca volvulus 0.0028 0.0039 0.032
Echinococcus multilocularis dual specificity 0.0186 0.0426 0.0426
Schistosoma mansoni ap endonuclease 0.0019 0.0016 0.0047
Entamoeba histolytica acyl-CoA synthetase, putative 0.0096 0.0206 0.1547
Brugia malayi Patched related family protein 12 0.0018 0.0014 0.0087
Brugia malayi hypothetical protein 0.0016 0.0009 0.0057
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0022 0.0025 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0016
Onchocerca volvulus Peroxidasin homolog 0.0013 0 0.0002
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0045 0.013
Loa Loa (eye worm) projectin 0.0013 0 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0284 0.0828
Mycobacterium ulcerans hypothetical protein 0.0021 0.0022 0.0037
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0014 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0436 0.1042 0.7824
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0084 0.0632
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0066 0.0497
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0121 0.0267 0.1018
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0053 0.0099 0.0187
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0008 0.0008
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0075 0.0462
Trichomonas vaginalis histone deacetylase, putative 0.0554 0.1332 1
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0008 0.0024
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0045 0.0274
Schistosoma mansoni histone deacetylase 0.0554 0.1332 0.3882
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0005 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0045 0.0274
Echinococcus multilocularis protein dispatched 1 0.0147 0.033 0.033
Plasmodium vivax SET domain protein, putative 0.0031 0.0046 0.0087
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0183 0.042 0.402
Onchocerca volvulus 0.0013 0 0.0002
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0047 0.0084 0.0516
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Brugia malayi N-terminal motif family protein 0.0183 0.042 0.2573
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0099 0.0604
Trypanosoma cruzi GMP reductase 0.0021 0.0022 0.0135
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0002 0.0016
Schistosoma mansoni hypothetical protein 0.0319 0.0752 0.2193
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0144
Brugia malayi histone deacetylase 11 0.028 0.0658 0.4028
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0115 0.0253 0.1549
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0042 0.026
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0019 0.0139
Onchocerca volvulus 0.0028 0.0039 0.032
Echinococcus multilocularis neuroligin 0.0034 0.0053 0.0053
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0045 0.013
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0014 0.0003 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0045 0.0274
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Toxoplasma gondii histone deacetylase HDAC1 0.0677 0.1632 0.3072
Echinococcus multilocularis flap endonuclease 1 0.0053 0.0101 0.0101
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0021 0.0022 0.0022
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0045 0.013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0045 0.0274
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0009 0.0027
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0053 0.0101 0.0617
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0554 0.1332 1
Brugia malayi hypothetical protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Toxoplasma gondii hypothetical protein 0.0018 0.0014 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0896
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.0238 0.0238
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0002 0.0014
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0028 0.0039 0.0141
Leishmania major histone deacetylase, putative 0.0677 0.1632 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0274
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0284 0.0828
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0014 0.0003 0.0018
Trichomonas vaginalis histone deacetylase, putative 0.0554 0.1332 1
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0014 0.0003 0.0018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0002 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0096 0.0206 0.1262
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0028 0.0039 0.0141
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0014 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0014 0.0003 0.0008
Echinococcus granulosus titin 0.0013 0 0.0001
Brugia malayi Carboxylesterase family protein 0.02 0.0462 0.2831
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0051
Onchocerca volvulus 0.0018 0.0014 0.0116
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.1072 0.2604 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0016
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Brugia malayi serine/threonine protein kinase 6 0.0176 0.0401 0.2455
Leishmania major DNA polymerase kappa, putative 0.0033 0.0052 0.0317
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0084 0.0632
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0093 0.027
Brugia malayi polk-prov protein 0.0087 0.0184 0.1127
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0002 0.0004
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0436 0.1042 0.7824
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0039 0.0069
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.0008 0.0057
Leishmania major hypothetical protein, conserved 0.0021 0.0022 0.0135
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Brugia malayi nuclear receptor RXR 0.0016 0.0009 0.0057
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0026 0.0076
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0005 0.0041
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0606 0.4551
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Toxoplasma gondii glycogen synthase, putative 0.0015 0.0005 0.001
Brugia malayi ImpB/MucB/SamB family protein 0.0108 0.0234 0.1435
Schistosoma mansoni chromosome transmission fidelity factor 0.003 0.0042 0.0124
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0237 0.0553 0.1611
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0002 0.0014
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0088 0.0185 0.0702
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0039 0.0239
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0045 0.0045
Trypanosoma brucei unspecified product 0.0074 0.0152 0.0932
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0098 0.021 0.1289
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0088 0.0185 0.0702
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0015 0.0008 0.0014
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0021 0.0022 0.0037
Schistosoma mansoni cell adhesion molecule 0.0013 0 0.0001
Brugia malayi hypothetical protein 0.0121 0.0268 0.164
Brugia malayi CXXC zinc finger family protein 0.0059 0.0113 0.0694
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.026
Trypanosoma brucei histone deacetylase 1 0.0554 0.1332 0.8158
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0046 0.0046
Onchocerca volvulus 0.0492 0.118 0.968
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0039 0.0293
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.0062 0.0122 0.0122
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0042 0.0079
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0166 0.0166
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0014 0.0003 0.0022
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0022 0.0135
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0053 0.0154
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0002 0.0014
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.0254 0.0477
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0284 0.0828
Loa Loa (eye worm) DR-78 0.0014 0.0005 0.0031
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0042 0.0316
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0186 0.0426 0.2607
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0239
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0045 0.0045
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.005 0.0093 0.0568
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0072 0.0146 0.0271
Mycobacterium ulcerans hypothetical protein 0.0162 0.0366 0.0686
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0246 0.0573 0.351
Echinococcus granulosus histone deacetylase 3 0.0554 0.1332 0.3882
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0084 0.0084
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.003 0.0042 0.096
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Schistosoma mansoni tyrosine kinase 0.0027 0.0035 0.0103
Echinococcus multilocularis para nitrobenzyl esterase 0.0034 0.0053 0.0053
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0323
Brugia malayi protein C24B5.3 0.0018 0.0014 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0045 0.0274
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0021 0.0022 0.0076
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0039 0.0239
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0096 0.0206 0.0384
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0005 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0009 0.0057
Trypanosoma brucei chrX additional, unordered contigs 0.0033 0.0052 0.0317
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0017 0.0103
Echinococcus multilocularis nibrin 0.003 0.0042 0.0042
Toxoplasma gondii IMP dehydrogenas 0.0021 0.0022 0.0042
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0108 0.0234 0.0683
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.0022 0.0149
Loa Loa (eye worm) hypothetical protein 0.0062 0.0122 0.0748
Brugia malayi jmjC domain containing protein 0.0063 0.0123 0.0754
Entamoeba histolytica histone deacetylase, putative 0.0554 0.1332 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0014 0.0003 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0316
Onchocerca volvulus 0.0018 0.0014 0.0116
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0039 0.0239
Trypanosoma brucei protein kinase, putative 0.0053 0.0099 0.0609
Schistosoma mansoni flap endonuclease-1 0.0048 0.0088 0.0257
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0045 0.0367
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0051
Loa Loa (eye worm) hypothetical protein 0.0045 0.0079 0.0486
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0002 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0016
Plasmodium vivax glutathione reductase, putative 0.0038 0.0064 0.012
Loa Loa (eye worm) TK/ROR protein kinase 0.0016 0.0009 0.0053
Schistosoma mansoni hypothetical protein 0.0124 0.0274 0.0799
Echinococcus granulosus H:Cl exchange transporter 3 0.0021 0.0022 0.0064
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0452 0.1079 0.661
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0019 0.0123
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0008 0.0024
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0002 0.0014
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0246 0.0573 0.0573
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0064 0.0185
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.03 0.0706 0.5301
Entamoeba histolytica recQ family helicase, putative 0.002 0.0019 0.0139
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0237 0.0553 0.4141
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0238 0.1789
Echinococcus multilocularis muscleblind protein 1 0.0606 0.146 0.146
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.0008 0.0047
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0028 0.0039 0.0069
Echinococcus granulosus importin subunit beta 1 0.003 0.0043 0.0125
Onchocerca volvulus 0.0452 0.1079 0.8855
Loa Loa (eye worm) fli-1 protein 0.0221 0.0511 0.3133
Loa Loa (eye worm) hypothetical protein 0.0087 0.0184 0.1127
Brugia malayi loechrig isoform VII 0.0237 0.0553 0.3387
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0016
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0034 0.0053 0.0053
Echinococcus multilocularis BC026374 protein (S09 family) 0.0034 0.0053 0.0053
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0002 0.0014
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0021 0.0022 0.0076
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0062 0.0377
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0045 0.0274
Trypanosoma cruzi protein kinase, putative 0.0018 0.0014 0.0084
Onchocerca volvulus 0.0014 0.0005 0.0041
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0084 0.0516
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Onchocerca volvulus Tyrosine kinase homolog 0.0508 0.1219 1
Trypanosoma brucei SNF1-related protein kinases, putative 0.005 0.0093 0.0568
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0166 0.0483
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0022 0.0025 0.015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0027 0.0165
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0183 0.042 0.0787
Echinococcus granulosus titin 0.0017 0.0011 0.0032
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0014 0.0003 0.0018
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0021 0.0022 0.0064
Echinococcus multilocularis Immunoglobulin 0.0021 0.0022 0.0022
Schistosoma mansoni importin beta-1 0.003 0.0043 0.0125
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0002 0.0016
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0075 0.0462
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0084 0.0244
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0238 0.146
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0062 0.0463
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0039 0.0293
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0008 0.0016
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0053 0.0099 0.029
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0096 0.0206 0.0384
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0016
Brugia malayi hypothetical protein 0.0051 0.0096 0.0587
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0039 0.0239
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Brugia malayi Prion-like- 0.0013 0 0.0002
Brugia malayi Niemann-Pick C1 protein precursor 0.03 0.0706 0.4325
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0112 0.0244 0.0244
Onchocerca volvulus 0.0018 0.0014 0.0116
Loa Loa (eye worm) loechrig isoform VII 0.0237 0.0553 0.3387
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0274
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0042 0.0079
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0064 0.0389
Loa Loa (eye worm) flap endonuclease-1 0.0053 0.0101 0.0617
Brugia malayi Ets-domain containing protein 0.0073 0.0148 0.0907
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0165
Brugia malayi chloride channel protein 7 0.0021 0.0022 0.0135
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0057
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0023 0.0027 0.0078
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0043 0.0263
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0896
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0002 0.0007
Plasmodium falciparum serine/threonine protein kinase, putative 0.0176 0.0401 0.0754
Loa Loa (eye worm) hypothetical protein 0.0409 0.0975 0.5972
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0014 0.0003 0.0018
Schistosoma mansoni 3-dehydroquinate synthase 0.0117 0.0257 0.0748
Giardia lamblia Hypothetical protein 0.0021 0.0022 0.0149
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.0008 0.0047
Loa Loa (eye worm) one IG domain family member 0.0013 0 0.0002
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0124 0.0274 0.0799
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0274
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0023 0.0044
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0064 0.0389
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0046 0.0135
Echinococcus granulosus sterol regulatory element binding protein 0.0129 0.0286 0.0832
Brugia malayi Patched related family protein 4 0.0018 0.0014 0.0087
Trypanosoma cruzi DNA polymerase eta, putative 0.0059 0.0115 0.0702
Trypanosoma brucei DNA polymerase eta, putative 0.0133 0.0297 0.1821
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0039 0.0239
Mycobacterium ulcerans acetyl-CoA synthetase 0.0028 0.0039 0.0069
Schistosoma mansoni ap endonuclease 0.0019 0.0016 0.0047
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0037 0.0062 0.0377
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.02 0.0462 0.1347
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.0039 0.0239
Echinococcus multilocularis replication factor c subunit 1 0.003 0.0042 0.0042
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Schistosoma mansoni ran 0.0022 0.0023 0.0068
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0084 0.0512
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0045 0.0045
Trypanosoma cruzi histone deacetylase, putative 0.028 0.0658 0.4028
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0039 0.0239
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0042 0.0318
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0323
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0016 0.0098
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0045 0.0274
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0 0.0002
Schistosoma mansoni nephrin 0.0034 0.0053 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Echinococcus granulosus cyclin dependent kinase 5 0.0047 0.0084 0.0245
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0014 0.0003 0.0018
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0084 0.0084
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.0238 0.0837
Echinococcus granulosus roundabout 2 0.0045 0.0079 0.0231
Echinococcus granulosus bloom syndrome protein 0.002 0.0019 0.0054
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0117 0.0257 0.0978
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0238 0.1789
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.005 0.0093 0.0568
Entamoeba histolytica protein kinase domain containing protein 0.0176 0.0401 0.3009
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0022
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0015 0.0008 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0029 0.0178
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0115 0.0335
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0027 0.0165
Schistosoma mansoni hypothetical protein 0.0037 0.0059 0.0173
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0014 0.0003 0.0018
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0098 0.021 0.021
Echinococcus multilocularis titin 0.0017 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.0037 0.0059 0.0446
Toxoplasma gondii histone deacetylase HDAC3 0.0554 0.1332 0.2507
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.026
Echinococcus granulosus cyclin dependent kinase 1 0.0047 0.0084 0.0245
Loa Loa (eye worm) glutaminase 2 0.0549 0.1319 0.8082
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0008 0.0024
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0028 0.0039 0.0141
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0021 0.0022 0.0064
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0075 0.0141
Schistosoma mansoni cpg binding protein 0.0062 0.0122 0.0354
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0254 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0158 0.0357 0.2185
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0005 0.0031
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.1072 0.2604 1
Schistosoma mansoni cell adhesion molecule 0.0013 0 0.0001
Schistosoma mansoni gabp alpha 0.0073 0.0148 0.0431
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0039 0.0066
Onchocerca volvulus 0.0096 0.0206 0.1691
Plasmodium falciparum DNA repair protein REV1, putative 0.0033 0.0052 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Echinococcus multilocularis twitchin 0.0017 0.0011 0.0011
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0252 0.059 0.3612
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0014 0.0003 0.0008
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0099 0.0747
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0045 0.013
Schistosoma mansoni titin 0.0013 0 0.0001
Loa Loa (eye worm) phosphofructokinase 0.0109 0.0238 0.146
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0088 0.0185 0.063
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0015 0.0008 0.0014
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0042 0.03
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0008 0.0051
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0017 0.0017
Brugia malayi Protein kinase domain containing protein 0.0186 0.0426 0.2607
Schistosoma mansoni protein kinase subunit gamma 0.0237 0.0553 0.1611
Plasmodium falciparum protein MAM3, putative 0.0021 0.0022 0.0042
Trypanosoma cruzi DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Loa Loa (eye worm) hypothetical protein 0.028 0.0658 0.4028
Brugia malayi Importin beta-1 subunit 0.003 0.0043 0.0263
Mycobacterium ulcerans hypothetical protein 0.0096 0.0206 0.0384
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0002 0.0014
Toxoplasma gondii serine/threonine specific protein phosphatase 0.0015 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0137 0.0516
Brugia malayi Patched related family protein 10 0.0018 0.0014 0.0087
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0002 0.0007
Brugia malayi Protein kinase domain containing protein 0.0047 0.0084 0.0516
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0021 0.0022 0.0022
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0216 0.05 0.05
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0021 0.0022 0.0474
Trypanosoma brucei GMP reductase 0.0021 0.0022 0.0135
Trypanosoma cruzi cdc2-related kinase 1 0.0047 0.0084 0.0516
Echinococcus granulosus serine:threonine protein kinase Nek1 0.0018 0.0014 0.004
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0008 0.0024
Echinococcus granulosus histone deacetylase 6 0.0677 0.1632 0.4758
Schistosoma mansoni coup transcription factor 0.0031 0.0045 0.013
Echinococcus multilocularis Niemann Pick C1 protein 0.0428 0.1022 0.1022
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0025 0.0184
Toxoplasma gondii NEK kinase 0.0022 0.0025 0.0046
Echinococcus granulosus histone deacetylase 7 0.0677 0.1632 0.4758
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0606 0.4551
Plasmodium vivax importin-beta 2, putative 0.003 0.0043 0.0081
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0005 0.0005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0318 0.0926
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0096 0.0587
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.03 0.0707 0.1328
Echinococcus granulosus carboxylesterase 5A 0.02 0.0462 0.1347
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0148 0.0907
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0436 0.1042 0.7824
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0162 0.0367 0.2753
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0112 0.0244 0.0711
Schistosoma mansoni topbp1 0.003 0.0042 0.0124
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0115 0.0253 0.1549
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0046 0.0135
Echinococcus multilocularis aurora kinase A 0.0176 0.0401 0.0401
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0166 0.1015
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0008 0.0016
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0019 0.0139
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0053 0.0099 0.0609
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0021 0.0022 0.0135
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0014 0.0003 0.0008
Echinococcus granulosus H:Cl exchange transporter 7 0.0021 0.0022 0.0064
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0039 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0606 0.4551
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Trypanosoma brucei unspecified product 0.0074 0.0152 0.0932
Trichomonas vaginalis histone deacetylase, putative 0.0554 0.1332 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Echinococcus multilocularis roundabout 2 0.0023 0.0027 0.0027
Entamoeba histolytica protein kinase, putative 0.0186 0.0426 0.3196
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0016 0.012
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0016 0.0098
Echinococcus multilocularis histone deacetylase 7 0.0677 0.1632 0.1632
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0112 0.0244 0.1817
Trichomonas vaginalis glutaminase, putative 0.0549 0.1319 0.9906
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.0008 0.0047
Brugia malayi Histone deacetylase family protein 0.0677 0.1632 1
Loa Loa (eye worm) IMP dehydrogenase 1 0.0021 0.0022 0.0135
Schistosoma mansoni hypothetical protein 0.0085 0.0178 0.052
Echinococcus multilocularis GPCR, family 2 0.008 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0057
Leishmania major importin beta-1 subunit, putative 0.0024 0.0029 0.0178
Plasmodium vivax DNA repair protein REV1, putative 0.0033 0.0052 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0045 0.0274
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0014 0.0003 0.0003
Schistosoma mansoni hemicentin 0.0013 0 0.0001
Onchocerca volvulus 0.0013 0 0.0002
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0008 0.0024
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0019 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Brugia malayi protein C24B5.3 0.0018 0.0014 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0045 0.0274
Trypanosoma brucei DNA damage repair protein, putative 0.0033 0.0052 0.0317
Plasmodium vivax histone deacetylase 2, putative 0.0677 0.1632 0.3072
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.03 0.0707 0.1328
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0053 0.0101 0.0617
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0045 0.013
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0016 0.003
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0265 0.1622
Trypanosoma cruzi cdc2-related kinase 3 0.0047 0.0084 0.0516
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0005 0.0005
Brugia malayi Carboxylesterase family protein 0.0034 0.0053 0.0323
Echinococcus granulosus intestinal type alkaline phosphatase 0.0164 0.0372 0.1083
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Brugia malayi Carboxylesterase family protein 0.0034 0.0053 0.0323
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0039 0.0141
Toxoplasma gondii CBS domain-containing protein 0.0021 0.0022 0.0042
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0263
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0186 0.0426 0.2607
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0323
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.0008 0.0047
Onchocerca volvulus 0.0031 0.0046 0.0381
Echinococcus granulosus microtubule associated protein 2 0.1409 0.3431 1
Giardia lamblia Hypothetical protein 0.0014 0.0003 0.0005
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0176 0.0401 0.0754
Echinococcus granulosus snurportin 1 0.0319 0.0752 0.2193
Loa Loa (eye worm) hypothetical protein 0.0254 0.0592 0.3629
Schistosoma mansoni DNA helicase recq5 0.002 0.0019 0.0054
Trypanosoma brucei DNA damage repair protein, putative 0.0033 0.0052 0.0317
Echinococcus granulosus serine:threonine kinase SAD 1 0.005 0.0093 0.027
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0016 0.0098
Mycobacterium ulcerans transcriptional regulator 0.0021 0.0022 0.0037
Trypanosoma brucei cdc2-related kinase 1 0.0047 0.0084 0.0516
Leishmania major histone deacetylase, putative 0.0677 0.1632 1
Loa Loa (eye worm) hypothetical protein 0.0252 0.059 0.3612
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0165
Plasmodium vivax patched family protein, putative 0.0018 0.0014 0.0027
Giardia lamblia Aurora kinase 0.0176 0.0401 0.2998
Onchocerca volvulus 0.0018 0.0014 0.0116
Plasmodium vivax histone deacetylase, putative 0.0677 0.1632 0.3072
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0053 0.0099 0.0609
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0316
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0183 0.042 0.0787
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0015 0.0008 0.0014
Brugia malayi serine/threonine-protein kinase 6 0.0176 0.0401 0.2455
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0066 0.0481
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0088 0.0185 0.0702
Brugia malayi nuclear receptor NHR-88 0.0031 0.0045 0.0274
Entamoeba histolytica acyl-coA synthetase, putative 0.0096 0.0206 0.1547
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0015 0.0008 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0436 0.1042 0.7824
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0028 0.0039 0.0069
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0165
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0039 0.0239
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Echinococcus granulosus histone deacetylase 0.0677 0.1632 0.4758
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0238 0.146
Onchocerca volvulus 0.0013 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0008 0.0051
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0005
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0022 0.0135
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0011 0.0032
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0002 0.0014
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0015 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Echinococcus multilocularis alkaline phosphatase 0.0164 0.0372 0.0372
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0023 0.0023
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0005 0.0031
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0018
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Schistosoma mansoni chloride channel protein 0.0021 0.0022 0.0064
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.003 0.0042 0.0318
Echinococcus multilocularis snurportin 1 0.0319 0.0752 0.0752
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.0206 0.0384
Schistosoma mansoni cell adhesion molecule 0.0032 0.0049 0.0142
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0008 0.0023
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0028 0.0039 0.0141
Echinococcus granulosus aurora kinase A 0.0176 0.0401 0.1168
Brugia malayi kettin 0.0013 0 0.0002
Trypanosoma brucei trypanothione reductase 0.0038 0.0064 0.0392
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0014 0.0003 0.0018
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0042 0.0318
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0051
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0053 0.0099 0.0609
Echinococcus granulosus tyrosine protein kinase otk 0.0023 0.0027 0.0078
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0002 0.0016
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0021 0.0022 0.0064
Leishmania major protein kinase, putative 0.0176 0.0401 0.2455
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0014 0.0003 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Onchocerca volvulus 0.024 0.0558 0.4582
Brugia malayi Pax transcription activation domain interacting protein 0.003 0.0042 0.026
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0042 0.0318
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0114
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Trypanosoma cruzi cdc2-related kinase 1 0.0047 0.0084 0.0516
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0015 0.0008 0.004
Plasmodium falciparum thioredoxin reductase 0.0038 0.0064 0.012
Toxoplasma gondii ck2 beta subunit 0.0037 0.0062 0.0116
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0008 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0098 0.021 0.1289
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0093 0.0697
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0436 0.1042 0.7824
Schistosoma mansoni septate junction protein 0.0023 0.0027 0.0078
Echinococcus granulosus dna polymerase eta 0.0133 0.0297 0.0866
Echinococcus granulosus twitchin 0.0038 0.0063 0.0185
Plasmodium vivax phosphodiesterase gamma, putative 0.0014 0.0003 0.0005
Trypanosoma brucei NIMA-related protein kinase 0.0022 0.0025 0.015
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0022 0.0135
Echinococcus multilocularis casein kinase ii subunit beta 0.0037 0.0062 0.0062
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.0008 0.0057
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0045 0.0045
Loa Loa (eye worm) patched family protein 0.0018 0.0014 0.0087
Brugia malayi hypothetical protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0238 0.146
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0045 0.013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0003 0.0005
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0008 0.0051
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0008 0.0008
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.0015 0.0005 0.001
Brugia malayi hypothetical protein 0.003 0.0042 0.026
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0017 0.0011 0.0068
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0028 0.0039 0.0141
Brugia malayi Voltage gated chloride channel family protein 0.0021 0.0022 0.0135
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0023 0.0144
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.0326 0.1998
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Schistosoma mansoni chloride channel protein 0.0021 0.0022 0.0064
Onchocerca volvulus 0.0013 0 0.0002
Schistosoma mansoni zinc finger protein 0.0014 0.0005 0.0015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0027 0.0165
Mycobacterium ulcerans hypothetical protein 0.0021 0.0022 0.0037
Plasmodium falciparum histone deacetylase, putative 0.0677 0.1632 0.3072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0027 0.0165
Schistosoma mansoni hypothetical protein 0.0834 0.2018 0.5882
Loa Loa (eye worm) hypothetical protein 0.0046 0.0082 0.0502
Mycobacterium tuberculosis Probable dehydrogenase 0.0088 0.0185 0.0702
Trichomonas vaginalis AGC family protein kinase 0.0176 0.0401 0.3009
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0057
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Trichomonas vaginalis histone deacetylase, putative 0.0554 0.1332 1
Echinococcus granulosus dna polymerase kappa 0.0162 0.0367 0.1069
Echinococcus granulosus H:Cl exchange transporter 4 0.0021 0.0022 0.0064
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0144
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Echinococcus multilocularis serine:threonine protein kinase Nek1 0.0018 0.0014 0.0014
Onchocerca volvulus 0.0018 0.0014 0.0116
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0084 0.0632
Plasmodium falciparum NIMA related kinase 2 0.0022 0.0025 0.0046
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.0238 0.0444
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0028 0.0039 0.0069
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0045 0.0045
Trypanosoma cruzi DNA polymerase kappa, putative 0.0162 0.0367 0.2246
Echinococcus multilocularis neuroglian 0.0034 0.0053 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0003 0.0018
Giardia lamblia Flap structure-specific endonuclease 0.0053 0.0101 0.0741
Brugia malayi jmjC domain containing protein 0.0059 0.0115 0.0704
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0034 0.0053 0.0154
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0003 0.0022
Schistosoma mansoni histone deacetylase 0.0554 0.1332 0.3882
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0097 0.0209 0.0723
Schistosoma mansoni hypothetical protein 0.0013 0 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0176 0.0401 0.3009
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0084 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.0426 0.1241
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0019 0.0054
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0059 0.0059
Plasmodium falciparum thioredoxin reductase 0.0013 0.0002 0.0004
Trypanosoma cruzi DNA damage repair protein, putative 0.0033 0.0052 0.0317
Loa Loa (eye worm) hypothetical protein 0.03 0.0706 0.4325
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0316
Toxoplasma gondii IQ calmodulin-binding motif domain-containing protein 0.0015 0.0005 0.001
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0005 0.0033
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0028 0.0039 0.0069
Plasmodium vivax protein kinase Crk2 0.0047 0.0084 0.0158
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0021 0.0022 0.0042
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0013 0 0.0001
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0115 0.0253 0.1549
Echinococcus multilocularis neuroglian 0.0023 0.0027 0.0027
Plasmodium vivax acyl-CoA synthetase, putative 0.0072 0.0146 0.0275
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0064 0.0185
Giardia lamblia Fructose-bisphosphate aldolase 0.0436 0.1042 0.782
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0039 0.0069
Onchocerca volvulus 0.0021 0.0022 0.0181
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0083 0.0174 0.0508
Schistosoma mansoni alkaline phosphatase 0.0164 0.0372 0.1083
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0046 0.0135
Brugia malayi nuclear receptor RXR 0.0014 0.0005 0.0031
Echinococcus granulosus contactin 0.0023 0.0027 0.0078
Brugia malayi hypothetical protein 0.0452 0.1079 0.661
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0083 0.0174 0.0508
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0022 0.0025 0.0046
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0045 0.013
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.0284 0.1739
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0045 0.0274
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0053 0.0101 0.019
Echinococcus granulosus roundabout 2 0.0023 0.0027 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0606 0.4551
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0021 0.0022 0.0135
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0387 0.2908
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0184 0.1127
Trichomonas vaginalis STE family protein kinase 0.0022 0.0025 0.0184
Leishmania major CBS domain protein, conserved 0.0021 0.0022 0.0135
Mycobacterium tuberculosis Conserved hypothetical protein 0.0108 0.0234 0.0892
Schistosoma mansoni histone deacetylase hda2 0.0689 0.1663 0.4847
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0037 0.0062 0.0377
Toxoplasma gondii histone deacetylase HDAC5 0.028 0.0658 0.1238
Schistosoma mansoni hypothetical protein 0.008 0.0166 0.0483
Trypanosoma brucei histone deacetylase 4 0.0677 0.1632 1
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0022 0.0025 0.0046
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0183 0.042 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Plasmodium falciparum acyl-CoA synthetase 0.0072 0.0146 0.0275
Plasmodium vivax glycogen synthase kinase 3, putative 0.0053 0.0099 0.0187
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.0146 0.0271
Schistosoma mansoni hypothetical protein 0.0023 0.0026 0.0076
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0005 0.0015
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0115 0.0335
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0087
Trypanosoma cruzi aurora B kinase, putative 0.0176 0.0401 0.2455
Loa Loa (eye worm) patched family protein 0.0018 0.0014 0.0087
Trichomonas vaginalis AGC family protein kinase 0.0176 0.0401 0.3009
Echinococcus multilocularis acetylcholinesterase 0.02 0.0462 0.0462
Brugia malayi jmjC domain containing protein 0.0016 0.0008 0.0051
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0053 0.0099 0.0099
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0052 0.0317
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0387 0.2908
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0096 0.018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0045 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0064 0.0477
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0164 0.0372 0.0372
Plasmodium falciparum histone deacetylase 1 0.0554 0.1332 0.2507
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0064 0.0477
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0238 0.1789
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.0096 0.0587
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0021 0.0022 0.0037
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0019 0.0035
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0053 0.0154
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0165
Brugia malayi CBS domain containing protein 0.0021 0.0022 0.0135
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0008 0.0051
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0019 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0045 0.0274
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0045 0.0274
Schistosoma mansoni titin 0.0013 0 0.0001
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0066 0.0124
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0042 0.0079
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0014 0.0003 0.0018
Echinococcus granulosus protein kinase shaggy 0.0053 0.0099 0.029
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0014 0.0003 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0436 0.1042 0.7824
Brugia malayi Patched family protein 0.0018 0.0014 0.0087
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0009 0.0057
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0023 0.0027 0.0221
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0108 0.0234 0.1435
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0003 0.0018
Mycobacterium ulcerans carboxylesterase, LipT 0.0034 0.0053 0.0095
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0021 0.0022 0.0076
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0051
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0042 0.0079
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0064 0.0389
Onchocerca volvulus 0.0013 0 0.0002
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0059 0.0173
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0436 0.1042 0.7824
Mycobacterium ulcerans hypothetical protein 0.0033 0.0052 0.0093
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0002 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0009 0.0057
Schistosoma mansoni cpg binding protein 0.0059 0.0113 0.033
Brugia malayi conserved hypotetical protein 0.0014 0.0005 0.0031
Schistosoma mansoni histone deacetylase 4 5 0.0677 0.1632 0.4758
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.003 0.0042 0.026
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0009 0.0027
Brugia malayi nuclear receptor NHR-88 0.0014 0.0005 0.0031
Onchocerca volvulus Protein patched homolog 0.0018 0.0014 0.0116
Brugia malayi TAR-binding protein 0.0128 0.0284 0.1739
Schistosoma mansoni lozenge 0.0057 0.0109 0.0317
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0084 0.0616
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0029 0.0218
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.016
Schistosoma mansoni titin 0.0023 0.0027 0.0078
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0045 0.0274
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0002 0.0016
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.0723 0.443
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0005 0.0015
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0022 0.0135
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0047 0.0084 0.0245
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0137 0.0516
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0042 0.0075
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0387 0.2908
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0057
Giardia lamblia DINP protein human, muc B family 0.0121 0.0267 0.1992
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0108 0.0234 0.0683
Loa Loa (eye worm) hypothetical protein 0.0096 0.0206 0.1262
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.0123 0.0359
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0027 0.0165
Loa Loa (eye worm) hypothetical protein 0.02 0.0462 0.2831
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0003 0.0018
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0016
Brugia malayi ancient conserved domain protein 4 0.0021 0.0022 0.0135
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Mycobacterium ulcerans glutaminase 0.0549 0.1319 0.248
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0023 0.0044
Brugia malayi Peroxidasin 0.0023 0.0027 0.0165
Echinococcus multilocularis protein kinase shaggy 0.0053 0.0099 0.0099
Echinococcus granulosus dnaJ subfamily B 0.0834 0.2018 0.5882
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0084 0.0245
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.0206 0.1262
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0016 0.0026
Brugia malayi Fibronectin type III domain containing protein 0.0021 0.0022 0.0135
Loa Loa (eye worm) chloride channel protein 7 0.0021 0.0022 0.0135
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0115 0.0115
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0084 0.0245
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0028 0.0039 0.0141
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0005
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0047 0.0084 0.0158
Giardia lamblia Casein kinase II beta chain 0.0037 0.0062 0.0447
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0062 0.0506
Giardia lamblia Kinase, CAMK CAMKL 0.005 0.0093 0.0681
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0014 0.0003 0.0018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0002 0.0016
Toxoplasma gondii thioredoxin reductase 0.0038 0.0064 0.012
Onchocerca volvulus Peroxidasin homolog 0.0013 0 0.0002
Schistosoma mansoni slit 0.0013 0 0.0001
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.0039 0.0073
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0062 0.0463
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0059 0.0173
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0014 0.0003 0.0022
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0039 0.0239
Echinococcus granulosus histone deacetylase 1 0.0554 0.1332 0.3882
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0039 0.0239
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.0238 0.0695
Onchocerca volvulus Alicorn homolog 0.0101 0.0217 0.178
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0025 0.0184
Schistosoma mansoni myosin-binding protein-related 0.0013 0 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0019 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0 0.0002

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.12 uM Inhibition of human PDE4 expressed in U937 cells using [3H]cAMP as substrate after 30 mins ChEMBL. 21955454
IC50 (functional) = 0.24 uM Inhibition of LPS-induced TNFalpha production in human PBMC preincubated 1 hr prior to LPS stimulation measured after 18 to 20 hrs by ELISA ChEMBL. 21955454
IC50 (functional) > 10 uM Cytotoxicity against human HCT116 cells assessed as reduction of [3H]thymidine incorporation after 72 hrs by scintillation counting ChEMBL. 21955454

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 21955454

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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