Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.1892 | 0.2546 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.026 | 0.286 | 0.3848 |
Onchocerca volvulus | 0.0021 | 0 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0656 | 0.5 |
Echinococcus granulosus | geminin | 0.0179 | 0.1892 | 0.2546 |
Echinococcus multilocularis | geminin | 0.0179 | 0.1892 | 0.1892 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.026 | 0.286 | 0.286 |
Echinococcus multilocularis | serotonin receptor | 0.0642 | 0.7431 | 0.7431 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.026 | 0.286 | 0.3848 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0656 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.0642 | 0.7431 | 0.7431 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0076 | 0.0656 | 0.0882 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0656 | 0.5 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0656 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0076 | 0.0656 | 0.0882 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0076 | 0.0656 | 0.0656 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0656 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0642 | 0.7431 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0281 | 0.3109 | 0.3109 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0642 | 0.7431 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.1892 | 0.2546 |
Schistosoma mansoni | thyroid hormone receptor | 0.0281 | 0.3109 | 0.4184 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.7431 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0281 | 0.3109 | 0.4184 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0656 | 0.0882 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.7431 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.