Detailed information for compound 156919

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 855.92 | Formula: C44H57NO16
  • H donors: 3 H acceptors: 8 LogP: 4.1 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCC(=O)O[C@@H]1C2=C(C)[C@@H](OC(=O)[C@@H]([C@@H](NC(=O)OC(C)(C)C)C=C(C)C)O)[C@H]3[C@@](C2(C)C)(OC(=O)O3)[C@H](C2[C@@](C1=O)(C)[C@@H](O)CC1[C@]2(CO1)OC(=O)C)Oc1ccccc1
  • InChi: 1S/C44H57NO16/c1-12-28(48)56-32-29-22(4)31(57-37(51)30(49)25(18-21(2)3)45-38(52)60-40(6,7)8)35-44(41(29,9)10,61-39(53)58-35)36(55-24-16-14-13-15-17-24)33-42(11,34(32)50)26(47)19-27-43(33,20-54-27)59-23(5)46/h13-18,25-27,30-33,35-36,47,49H,12,19-20H2,1-11H3,(H,45,52)/t25-,26-,27?,30+,31+,32+,33?,35-,36-,42+,43-,44+/m0/s1
  • InChiKey: NITTXNSIJDONSB-FFVKEPDKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0632 0.063
Leishmania major cysteine peptidase A (CPA) 0.0113 0.0352 0.3486
Echinococcus multilocularis 0.059 0.23 0.2298
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0033 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0014
Plasmodium vivax serine-repeat antigen (SERA) 0.0052 0.0102 0.0721
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0041 0.0039
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0048 0.0088 0.0112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0027 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0014
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0145 0.0482 0.048
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0028 0.0007 0.0005
Onchocerca volvulus 0.003 0.0012 0.0026
Loa Loa (eye worm) PHD-finger family protein 0.0123 0.0395 0.0513
Plasmodium vivax vivapain-2 0.0113 0.0352 0.2618
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0108
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0007 0.0009
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.0319 0.3328
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0108
Echinococcus multilocularis neuropeptide receptor A26 0.0456 0.1754 0.1753
Onchocerca volvulus 0.0094 0.0275 0.072
Plasmodium falciparum serine repeat antigen 8 0.0052 0.0102 0.0721
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Plasmodium vivax unspecified product 0.0053 0.0108 0.0768
Brugia malayi RNA binding protein 0.0063 0.0151 0.0193
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0432 0.1655 0.6448
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0102 0.013
Echinococcus multilocularis epidermal growth factor receptor 0.1029 0.4097 0.4095
Schistosoma mansoni cathepsin C 0.0052 0.0102 0.01
Brugia malayi hypothetical protein 0.0029 0.0011 0.0012
Schistosoma mansoni hypothetical protein 0.0088 0.0249 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0024 0.004
Toxoplasma gondii cathepsin CPL 0.0113 0.0352 0.2616
Giardia lamblia Encystation-specific protease 0.0052 0.0102 0.0633
Schistosoma mansoni chromobox protein 0.0069 0.0172 0.017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0027 0.002
Schistosoma mansoni endoplasmin 0.0093 0.027 0.0268
Brugia malayi Cathepsin L-like precursor 0.0113 0.0352 0.0455
Mycobacterium tuberculosis Probable reductase 0.0432 0.1655 0.6448
Mycobacterium tuberculosis Probable oxidoreductase 0.048 0.1852 0.7226
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0052 0.0102 0.0191
Brugia malayi Bromodomain containing protein 0.0105 0.0321 0.0415
Brugia malayi mbt repeat family protein 0.0094 0.0275 0.0354
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0037 0.0173
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Schistosoma mansoni protein phosphatase 2C 0.0028 0.0007 0.0005
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0113 0.0352 0.035
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0196 0.0632
Echinococcus multilocularis Immunoglobulin 0.0029 0.0011 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.016 0.0545 0.1801
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0052 0.0102 0.0721
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0051 0.0331
Trichomonas vaginalis endoplasmin, putative 0.0067 0.0166 0.0315
Echinococcus granulosus SAM and MBT domain containing protein 0.0094 0.0275 0.0273
Plasmodium falciparum heat shock protein 90 0.0093 0.027 0.1994
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0049 0.0089
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0037 0.0066
Loa Loa (eye worm) inositol-1 0.0036 0.0037 0.0048
Brugia malayi Cathepsin L-like precursor 0.0053 0.0108 0.0138
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0352 0.0675
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0041 0.0027
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0082 0.008
Plasmodium vivax hypothetical protein, conserved 0.0088 0.0249 0.1837
Loa Loa (eye worm) mbt repeat family protein 0.0094 0.0275 0.0357
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0113 0.0352 0.2618
Onchocerca volvulus 0.0113 0.0352 0.0924
Schistosoma mansoni hypothetical protein 0.0578 0.2253 0.2251
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0008 0.0011
Trypanosoma cruzi heat shock protein 90, putative 0.0079 0.0215 0.0697
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0102 0.0191
Echinococcus multilocularis cathepsin L 0.0105 0.0319 0.0317
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.0215 0.028
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0041 0.0039
Schistosoma mansoni cpg binding protein 0.0195 0.0688 0.0686
Plasmodium vivax vivapain-3 0.0105 0.0319 0.2365
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0082 0.0574
Trichomonas vaginalis heat shock protein, putative 0.0079 0.0215 0.041
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0052 0.0102 0.0721
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0181 0.0632 0.063
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0066 0.0159 1
Onchocerca volvulus 0.0135 0.0442 0.1162
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0057 0.0124 0.0233
Loa Loa (eye worm) hypothetical protein 0.0298 0.111 0.1442
Echinococcus granulosus cathepsin b 0.076 0.2996 0.2995
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0113 0.0352 0.0457
Toxoplasma gondii heat shock protein 90, putative 0.0093 0.027 0.1992
Onchocerca volvulus 0.0435 0.1668 0.4397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2655
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0352 0.0675
Loa Loa (eye worm) hypothetical protein 0.0422 0.1617 0.2101
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0048 0.0086 0.0084
Giardia lamblia Cathepsin B precursor 0.0052 0.0102 0.0633
Brugia malayi Muscleblind-like protein 0.015 0.0503 0.0651
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.1294 0.5176 0.6723
Schistosoma mansoni tyrosine kinase 0.081 0.3199 0.3198
Plasmodium falciparum serine repeat antigen 3 0.0052 0.0102 0.0721
Echinococcus multilocularis lysine specific demethylase 5A 0.0106 0.0324 0.0322
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0377 0.1433 0.1431
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.076 0.2996 0.2995
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0083 0.0689
Echinococcus multilocularis cpg binding protein 0.0195 0.0688 0.0686
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Schistosoma mansoni hypothetical protein 0.0171 0.0591 0.0589
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0066 0.0159 0.1539
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0052 0.0102 0.0721
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0002 0.0003
Loa Loa (eye worm) cysteine protease 0.0113 0.0352 0.0457
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.1294 0.5176 0.6724
Brugia malayi Pre-SET motif family protein 0.0124 0.0396 0.0512
Schistosoma mansoni phosphatidylserine receptor 0.0028 0.0007 0.0005
Onchocerca volvulus 0.0113 0.0352 0.0924
Echinococcus multilocularis cathepsin b 0.076 0.2996 0.2995
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0352 0.0675
Echinococcus granulosus cathepsin l1 0.0113 0.0352 0.035
Plasmodium falciparum thioredoxin reductase 0.0066 0.0159 0.1156
Loa Loa (eye worm) hypothetical protein 0.0053 0.0108 0.014
Loa Loa (eye worm) ctsf protein 0.0113 0.0352 0.0457
Schistosoma mansoni jumonji domain containing protein 0.0028 0.0007 0.0005
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0115 0.0363 0.0361
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0029 0.0011 0.0009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.076 0.2996 0.2995
Leishmania major cathepsin L-like protease 0.016 0.0545 0.5436
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0009
Brugia malayi hypothetical protein 0.0072 0.0186 0.0239
Toxoplasma gondii thioredoxin reductase 0.0189 0.0664 0.4984
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0027 0.002
Echinococcus granulosus neuropeptide s receptor 0.0456 0.1754 0.1753
Echinococcus granulosus epidermal growth factor receptor 0.1029 0.4097 0.4095
Plasmodium falciparum cysteine proteinase falcipain 3 0.0113 0.0352 0.2618
Echinococcus granulosus roundabout 2 0.0046 0.0081 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0113 0.0352 0.0675
Loa Loa (eye worm) hypothetical protein 0.005 0.0094 0.0122
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0105 0.0319 0.1043
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0189 0.0664 0.2538
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0113 0.0352 0.0457
Schistosoma mansoni jumonji/arid domain-containing protein 0.0127 0.0411 0.0409
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0052 0.0102 0.0721
Echinococcus granulosus transcription factor btf3 0.0069 0.0172 0.017
Loa Loa (eye worm) CHromoDomain protein family member 0.0033 0.0024 0.0032
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0066 0.0159 0.051
Leishmania major cathepsin L-like protease 0.016 0.0545 0.5436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0047 0.0082 0.0574
Entamoeba histolytica heat shock protein 90, putative 0.0093 0.027 0.278
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0061 0.0155
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0037 0.023
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2655
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0052 0.0102 0.0899
Echinococcus multilocularis roundabout 2 0.0046 0.0081 0.0079
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0135 0.0442 0.044
Entamoeba histolytica hypothetical protein 0.0069 0.0172 0.1689
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0108 0.0339
Loa Loa (eye worm) hypothetical protein 0.025 0.0914 0.1187
Echinococcus granulosus peregrin 0.0105 0.0321 0.0319
Brugia malayi hypothetical protein 0.0074 0.0196 0.0252
Entamoeba histolytica transcription factor BTF3, putative 0.0069 0.0172 0.1689
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0052 0.0102 0.0132
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0652 0.2554 1
Trypanosoma brucei heat shock protein 90, putative 0.0093 0.027 0.2655
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0468 0.0466
Schistosoma mansoni hypothetical protein 0.0029 0.0008 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.051
Echinococcus multilocularis neuroglian 0.0037 0.0042 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0052 0.0102 0.0191
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2655
Brugia malayi fibroinase precursor 0.0052 0.0102 0.013
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0145 0.0482 0.048
Loa Loa (eye worm) hypothetical protein 0.0088 0.0249 0.0324
Brugia malayi protein kinase C3,putative 0.0262 0.096 0.1245
Trypanosoma brucei ISWI complex protein 0.0091 0.0265 0.2604
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0029 0.0008 0.0011
Trichomonas vaginalis set domain proteins, putative 0.0954 0.379 0.7322
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0049 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.0895 0.3545 0.6848
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0041 0.0349
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0066 0.0159 0.1155
Leishmania major heat shock protein, putative 0.0062 0.0143 0.1372
Schistosoma mansoni hypothetical protein 0.2475 1 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0048 0.0086 0.0084
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0082 0.008
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.0215 0.0213
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0051 0.0103
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0141 0.0467 0.4992
Onchocerca volvulus 0.0954 0.379 1
Entamoeba histolytica cysteine protease, putative 0.0113 0.0352 0.3702
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0062 0.0143 0.0141
Brugia malayi Cathepsin L-like precursor 0.006 0.0135 0.0173
Echinococcus multilocularis muscleblind protein 1 0.015 0.0503 0.0501
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Schistosoma mansoni zinc finger protein 0.0091 0.0265 0.0263
Onchocerca volvulus 0.003 0.0015 0.0034
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2655
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0288 0.1067 0.4098
Brugia malayi cathepsin F-like cysteine proteinase 0.0052 0.0102 0.013
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0615 0.2402 0.2401
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0491 0.1895 0.2462
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0035 0.0051
Schistosoma mansoni nephrin 0.0037 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0045
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Plasmodium vivax heat shock protein 90, putative 0.0062 0.0143 0.1031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0319 0.0611
Loa Loa (eye worm) hypothetical protein 0.0107 0.0328 0.0426
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0172 0.0328
Trypanosoma cruzi ISWI complex protein 0.0091 0.0265 0.0862
Echinococcus granulosus raf serine:threonine protein kinase 0.0035 0.0033 0.0031
Entamoeba histolytica cysteine protease, putative 0.0052 0.0102 0.0899
Trypanosoma cruzi heat shock protein 85, putative 0.0093 0.027 0.0879
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0271 0.0997 0.1922
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Loa Loa (eye worm) endoplasmin 0.0093 0.027 0.035
Echinococcus multilocularis thioredoxin glutathione reductase 0.0189 0.0664 0.0663
Brugia malayi AF-10 protein 0.0029 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Giardia lamblia Cathepsin L precursor 0.0052 0.0102 0.0633
Onchocerca volvulus 0.0047 0.0083 0.0214
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0159 0.0542 0.054
Plasmodium falciparum serine repeat antigen 6 0.0052 0.0102 0.0721
Schistosoma mansoni tyrosine kinase 0.0615 0.2402 0.2401
Loa Loa (eye worm) bromodomain containing protein 0.0109 0.0337 0.0438
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0066 0.0159 0.1539
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0045
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0041 0.0075
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0124 0.0396 0.0394
Echinococcus granulosus neuropeptide receptor A26 0.0456 0.1754 0.1753
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0102 0.0307 0.0305
Brugia malayi F/Y-rich N-terminus family protein 0.0098 0.029 0.0374
Toxoplasma gondii cathepsin CPC1 0.0052 0.0102 0.072
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0066 0.0159 0.1156
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.076 0.2996 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0047 0.0082 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.0319 0.3149
Trichomonas vaginalis glutathione reductase, putative 0.0066 0.0159 0.0302
Echinococcus granulosus heat shock protein 90 0.0093 0.027 0.0268
Echinococcus multilocularis polycomb protein SCMH1 0.0094 0.0275 0.0273
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0052 0.0102 0.0633
Toxoplasma gondii NADPH-glutathione reductase 0.0066 0.0159 0.1155
Giardia lamblia Cathepsin L precursor 0.0052 0.0102 0.0633
Mycobacterium ulcerans hypothetical protein 0.0047 0.0083 0.0193
Trichomonas vaginalis glucosylceramidase, putative 0.0895 0.3545 0.6848
Echinococcus granulosus histone lysine methyltransferase setb 0.0225 0.0812 0.081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0632 0.063
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0172 0.0328
Trichomonas vaginalis bromodomain-containing protein, putative 0.0057 0.0124 0.0233
Brugia malayi Cathepsin L-like cysteine proteinase 0.006 0.0135 0.0173
Schistosoma mansoni cathepsin S (C01 family) 0.0052 0.0102 0.01
Trypanosoma cruzi heat shock protein 85, putative 0.0079 0.0215 0.0697
Trypanosoma cruzi cysteine peptidase, putative 0.0105 0.0319 0.1043
Brugia malayi cathepsin Z-like cysteine proteinase 0.0052 0.0102 0.013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.051
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Echinococcus granulosus cathepsin L 0.0052 0.0102 0.01
Echinococcus granulosus chromobox protein 1 0.0069 0.0172 0.017
Trypanosoma cruzi Heat shock protein 83, putative 0.0093 0.027 0.0879
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0287 0.1063 0.1061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0102 0.0191
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0051 0.0098 0.0184
Trichomonas vaginalis heat shock protein, putative 0.0087 0.0246 0.0471
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0052 0.0102 0.0721
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0008 0.0015
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.0215 0.0277
Entamoeba histolytica hypothetical protein 0.0072 0.0186 0.1844
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0062 0.0143 0.0141
Echinococcus granulosus polycomb protein SCMH1 0.0094 0.0275 0.0273
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0033 0.0024 0.0022
Brugia malayi heat shock protein 90 0.0093 0.027 0.0348
Treponema pallidum heat shock protein 90 0.0087 0.0246 0.4817
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0113 0.0352 0.0675
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0151 0.0149
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Plasmodium vivax basic transcription factor 3b, putative 0.0069 0.0172 0.1256
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0052 0.0102 0.0899
Echinococcus granulosus cathepsin l cysteine peptidase 0.0113 0.0352 0.035
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.005 0.0144
Entamoeba histolytica cysteine proteinase 1, putative 0.0105 0.0319 0.3328
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0029 0.0011 0.0009
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0087 0.0246 1
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0352 0.3702
Onchocerca volvulus Alhambra homolog 0.0088 0.0249 0.0652
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0061 0.0112
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0181 0.0632 0.0821
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0052 0.0102 0.0633
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0014
Brugia malayi protein kinase C II. 0.0043 0.0067 0.0085
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0053 0.0108 0.014
Trichomonas vaginalis heat shock protein, putative 0.0093 0.027 0.0516
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0083 0.0105
Trypanosoma cruzi cysteine peptidase, putative 0.016 0.0545 0.1801
Brugia malayi Cathepsin L-like precursor 0.0113 0.0352 0.0455
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0052 0.0102 0.0191
Giardia lamblia Cathepsin L precursor 0.0052 0.0102 0.0633
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0066 0.0159 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0102 0.0191
Giardia lamblia Cathepsin L precursor 0.0052 0.0102 0.0633
Loa Loa (eye worm) jmjC domain-containing protein 0.0127 0.0411 0.0535
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0087 0.0246 0.242
Echinococcus multilocularis transcription factor btf3 0.0069 0.0172 0.017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0012 0.0017
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0037 0.0009
Entamoeba histolytica hypothetical protein 0.0052 0.0102 0.0899
Schistosoma mansoni hypothetical protein 0.1693 0.6808 0.6807
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0215 0.0768 0.0766
Toxoplasma gondii PHD-finger domain-containing protein 0.0088 0.0249 0.1836
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Loa Loa (eye worm) hypothetical protein 0.0094 0.0275 0.0357
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0027 0.002
Onchocerca volvulus Glucosylceramidase homolog 0.0849 0.3359 0.8861
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0014
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Plasmodium vivax heat shock protein, putative 0.0351 0.1325 1
Onchocerca volvulus 0.005 0.0094 0.0242
Loa Loa (eye worm) PHD-finger family protein 0.0088 0.0249 0.0324
Brugia malayi jmjC domain containing protein 0.0028 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0039 0.005 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Echinococcus granulosus thioredoxin glutathione reductase 0.0189 0.0664 0.0663
Leishmania major trypanothione reductase 0.0189 0.0664 0.6641
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0279 0.1033 0.1342
Echinococcus multilocularis chromobox protein 1 0.0069 0.0172 0.017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.076 0.2996 0.2995
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Echinococcus multilocularis GPCR, family 2 0.0079 0.0215 0.0213
Echinococcus granulosus cysteine protease 0.0105 0.0319 0.0317
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0043 0.0067 0.0065
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0066 0.0159 0.0494
Echinococcus multilocularis heat shock protein 90 0.0079 0.0215 0.0213
Schistosoma mansoni zinc finger protein 0.013 0.0424 0.0422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Schistosoma mansoni methyl-cpg binding protein mbd 0.0102 0.0307 0.0305
Entamoeba histolytica hypothetical protein 0.0072 0.0186 0.1844
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0037 0.0035
Brugia malayi TAR-binding protein 0.0063 0.0151 0.0193
Loa Loa (eye worm) hypothetical protein 0.015 0.0503 0.0653
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0181 0.0632 0.063
Echinococcus multilocularis geminin 0.1693 0.6808 0.6807
Giardia lamblia Cysteine protease 0.0052 0.0102 0.0633
Schistosoma mansoni endoplasmin 0.0093 0.027 0.0268
Brugia malayi CHD4 protein 0.0033 0.0024 0.0029
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0082 0.0764
Echinococcus granulosus cathepsin L cysteine proteinase 0.0113 0.0352 0.035
Brugia malayi jmjC domain containing protein 0.0127 0.0411 0.0532
Loa Loa (eye worm) heat shock protein 90 0.0093 0.027 0.035
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Plasmodium vivax unspecified product 0.0052 0.0102 0.0721
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0041 0.0116
Toxoplasma gondii cathepsin B 0.0271 0.0997 0.7505
Schistosoma mansoni cpg binding protein 0.0174 0.0601 0.0599
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0011 0.0009
Brugia malayi Latrophilin receptor protein 2 0.0079 0.0215 0.0277
Loa Loa (eye worm) hypothetical protein 0.005 0.0095 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Echinococcus multilocularis dnaJ subfamily B 0.2475 1 1
Brugia malayi Cathepsin L-like precursor 0.0113 0.0352 0.0455
Brugia malayi Cathepsin L-like precursor 0.0113 0.0352 0.0455
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0029 0.0011 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Entamoeba histolytica cysteine protease, putative 0.0052 0.0102 0.0899
Brugia malayi Bromodomain containing protein 0.0232 0.084 0.109
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0019
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.0215 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0033 0.0031
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Echinococcus multilocularis isocitrate dehydrogenase 0.0047 0.0082 0.008
Giardia lamblia Cathepsin L-like protease 0.0052 0.0102 0.0633
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0051 0.0098 0.0184
Echinococcus granulosus fetal alzheimer antigen falz 0.0145 0.0482 0.048
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0186 0.0184
Loa Loa (eye worm) cathepsin B 0.0271 0.0997 0.1295
Echinococcus granulosus protein kinase c epsilon type 0.0043 0.0067 0.0065
Giardia lamblia Cysteine protease 0.0052 0.0102 0.0633
Trypanosoma cruzi ISWI complex protein 0.0091 0.0265 0.0862
Toxoplasma gondii cathepsin CPC2 0.0052 0.0102 0.072
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0045
Schistosoma mansoni hypothetical protein 0.0079 0.0215 0.0213
Brugia malayi latrophilin 2 splice variant baaae 0.0171 0.0591 0.0766
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0041 0.0349
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0151 0.0149
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0014
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0047 0.0082 0.0574
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Brugia malayi jmjC domain containing protein 0.0028 0.0007 0.0006
Giardia lamblia Fructose-bisphosphate aldolase 0.0141 0.0467 0.4455
Giardia lamblia NADH oxidase lateral transfer candidate 0.0066 0.0159 0.1233
Echinococcus granulosus protein tyrosine kinase 0.081 0.3199 0.3198
Giardia lamblia Hypothetical protein 0.0052 0.0102 0.0633
Loa Loa (eye worm) hypothetical protein 0.006 0.0135 0.0176
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.0024 0.0022
Schistosoma mansoni hypothetical protein 0.0033 0.0028 0.0026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0024 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0102 0.0191
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0196 0.1432
Entamoeba histolytica cysteine protease, putative 0.0052 0.0102 0.0899
Brugia malayi CXXC zinc finger family protein 0.0174 0.0601 0.0779
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0352 0.3702
Echinococcus multilocularis heat shock protein 0.0093 0.027 0.0268
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0052 0.0102 0.0191
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0052 0.0102 0.01
Trypanosoma cruzi heat shock protein, putative 0.0062 0.0143 0.0455
Onchocerca volvulus Cathepsin L homolog 0.0113 0.0352 0.0924
Schistosoma mansoni cathepsin F (C01 family) 0.006 0.0135 0.0133
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0101
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0094 0.0092
Echinococcus granulosus epidermal growth factor receptor 0.1911 0.7697 0.7697
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0377 0.1433 0.1431
Leishmania major cathepsin L-like protease 0.0113 0.0352 0.3486
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0066 0.0159 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Mycobacterium tuberculosis Probable dehydrogenase 0.0432 0.1655 0.6448
Brugia malayi isocitrate dehydrogenase 0.0047 0.0082 0.0105
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0067 0.0065
Echinococcus multilocularis JmjC domain containing protein 4 0.0028 0.0007 0.0005
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0271 0.0997 0.3312
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.0215 0.0213
Brugia malayi SET domain containing protein 0.003 0.0012 0.0013
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0057 0.0124 0.0885
Schistosoma mansoni heat shock protein 0.0093 0.027 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.006 0.0135 0.0256
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0053 0.0108 0.0138
Trypanosoma brucei cysteine peptidase C (CPC) 0.0271 0.0997 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0081 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0052 0.0102 0.0191
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0113 0.0352 0.2618
Trypanosoma cruzi heat shock protein 85, putative 0.0093 0.027 0.0879
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Entamoeba histolytica cysteine protease, putative 0.0052 0.0102 0.0899
Echinococcus multilocularis tumor protein p63 0.0339 0.1274 0.1272
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Brugia malayi Furin-like cysteine rich region family protein 0.1911 0.7697 1
Loa Loa (eye worm) ICD-1 protein 0.0069 0.0172 0.0224
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0102 0.013
Schistosoma mansoni SET domain protein 0.003 0.0012 0.001
Plasmodium vivax vivapain-2 0.0113 0.0352 0.2618
Trypanosoma cruzi heat shock protein 90, putative 0.0093 0.027 0.0879
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0225 0.0812 0.081
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0047 0.0082 0.0764
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0057 0.0124 0.0885
Echinococcus granulosus chromobox protein 1 0.0069 0.0172 0.017
Toxoplasma gondii preprocathepsin c precursor, putative 0.0052 0.0102 0.072
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Onchocerca volvulus 0.0052 0.0102 0.0264
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1029 0.4097 0.4095
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0066 0.0159 0.051
Loa Loa (eye worm) histone methyltransferase 0.0058 0.0129 0.0167
Plasmodium falciparum serine repeat antigen 5 0.0052 0.0102 0.0721
Loa Loa (eye worm) hypothetical protein 0.0046 0.0081 0.0105
Brugia malayi PHD-finger family protein 0.0088 0.0249 0.0321
Brugia malayi Papain family cysteine protease containing protein 0.0105 0.0319 0.0411
Echinococcus multilocularis raf serine:threonine protein kinase 0.0035 0.0033 0.0031
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0037 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0172 0.0328
Leishmania major hypothetical protein, conserved 0.0091 0.0265 0.2604
Schistosoma mansoni jumonji domain containing protein 0.0228 0.0822 0.082
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0082 0.0574
Schistosoma mansoni myelin transcription factor 1 myt1 0.0107 0.0328 0.0326
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0083 0.0193
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Brugia malayi Inositol-1 0.0036 0.0037 0.0046
Echinococcus granulosus methyl CpG binding domain protein 2 0.0102 0.0307 0.0305
Echinococcus multilocularis microtubule associated protein 2 0.136 0.5447 0.5446
Echinococcus multilocularis heat shock protein 90 0.0093 0.027 0.0268
Echinococcus granulosus Immunoglobulin 0.0029 0.0011 0.0009
Brugia malayi hypothetical protein 0.0048 0.0088 0.0111
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0066 0.0159 0.1539
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.006 0.0135 0.0256
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0083 0.0689
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0052 0.0102 0.0633
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0151 0.0149
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0048 0.0086 0.0084
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0002 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0352 0.0675
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0181 0.0632 0.063
Onchocerca volvulus Tyrosine kinase homolog 0.0459 0.1767 0.4659
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0432 0.1655 0.6448
Plasmodium falciparum zinc finger protein, putative 0.0032 0.0022 0.0113
Echinococcus multilocularis cathepsin L cysteine protease 0.0113 0.0352 0.035
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0052 0.0102 0.0721
Echinococcus granulosus cathepsin L cysteine protease 0.0105 0.0319 0.0317
Plasmodium vivax SET domain protein, putative 0.0124 0.0396 0.2953
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0041 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0172 0.0328
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.1539
Brugia malayi Thioredoxin reductase 0.0189 0.0664 0.0861
Loa Loa (eye worm) isocitrate dehydrogenase 0.0047 0.0082 0.0107
Toxoplasma gondii LsmAD domain-containing protein 0.0074 0.0196 0.1431
Entamoeba histolytica cysteine proteinase 2 0.0105 0.0319 0.3328
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0108
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.048 0.1852 0.7226
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0306
Brugia malayi Papain family cysteine protease containing protein 0.0105 0.0319 0.0411
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0111 0.021
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0066 0.0159 0.0543
Echinococcus granulosus heat shock protein 90 0.0079 0.0215 0.0213
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0102 0.01
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0105 0.0319 0.0317
Echinococcus multilocularis cathepsin L cysteine protease 0.0113 0.0352 0.035
Echinococcus granulosus tar DNA binding protein 0.0063 0.0151 0.0149
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0083 0.0242
Giardia lamblia Cysteine protease 0.0052 0.0102 0.0633
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0094 0.0275 0.072
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0196 0.1432
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.051
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.1539
Schistosoma mansoni tyrosine kinase 0.1013 0.4028 0.4027
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0107 0.0328 0.0326
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Loa Loa (eye worm) thioredoxin reductase 0.0189 0.0664 0.0863
Brugia malayi beta-NAC-like protein 0.0069 0.0172 0.0221
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0225 0.0812 0.081
Plasmodium falciparum serine repeat antigen 1 0.0052 0.0102 0.0721
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0107 0.0328 0.1075
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.0319 0.3328
Schistosoma mansoni heat shock protein 0.0062 0.0143 0.0141
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0352 0.0675
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0151 0.0149
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Trypanosoma cruzi cysteine proteinase, putative 0.0105 0.0319 0.1043
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0124 0.0396 0.2951
Loa Loa (eye worm) hypothetical protein 0.0053 0.0108 0.014
Onchocerca volvulus 0.0113 0.0352 0.0924
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Brugia malayi Protein kinase domain containing protein 0.0615 0.2402 0.3119
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0066 0.0159 0.1156
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0066 0.0159 0.1539
Giardia lamblia Cathepsin L-like protease 0.0052 0.0102 0.0633
Trypanosoma cruzi trypanothione reductase, putative 0.0189 0.0664 0.22
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0083 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0048 0.0088 0.0112
Toxoplasma gondii Hsp90 domain-containing protein 0.0351 0.1325 0.9993
Schistosoma mansoni hypothetical protein 0.0072 0.0186 0.0184
Plasmodium vivax ataxin-2 like protein, putative 0.0074 0.0196 0.1432
Giardia lamblia Cathepsin L precursor 0.0052 0.0102 0.0633
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0039 0.0052 0.0339
Trypanosoma cruzi cysteine peptidase, putative 0.016 0.0545 0.1801
Brugia malayi Isocitrate dehydrogenase 0.0047 0.0082 0.0105
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0083 0.0193
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0052 0.0102 0.0132
Plasmodium vivax vivapain-1 0.0105 0.0319 0.2365
Loa Loa (eye worm) hypothetical protein 0.0052 0.0102 0.0132
Echinococcus multilocularis lysine specific demethylase 6a 0.0028 0.0007 0.0005
Giardia lamblia Cathepsin B precursor 0.0052 0.0102 0.0633
Loa Loa (eye worm) TK/EGFR protein kinase 0.1911 0.7697 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0082 0.008
Brugia malayi PHD-finger family protein 0.0162 0.0554 0.0718
Giardia lamblia Heat shock protein HSP 90-alpha 0.0093 0.027 0.2389
Trypanosoma brucei trypanothione reductase 0.0189 0.0664 0.6641
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0151 0.0196
Echinococcus multilocularis phd:f box containing protein 0.0028 0.0007 0.0005
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0172 0.0554
Loa Loa (eye worm) glutathione reductase 0.0189 0.0664 0.0863
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Echinococcus multilocularis chromobox protein 1 0.0069 0.0172 0.017
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.0275 0.0273
Loa Loa (eye worm) MH2 domain-containing protein 0.0352 0.1327 0.1724
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0839 0.3319 0.4312
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0041 0.0221
Trypanosoma brucei heat shock protein 84, putative 0.0062 0.0143 0.1372
Loa Loa (eye worm) hypothetical protein 0.0039 0.0049 0.0063
Entamoeba histolytica cysteine protease, putative 0.0052 0.0102 0.0899
Brugia malayi cathepsin L precursor 0.0052 0.0102 0.013
Loa Loa (eye worm) CXXC zinc finger family protein 0.0174 0.0601 0.0781
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0083 0.0105
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0432 0.1655 0.6448
Plasmodium vivax unspecified product 0.0105 0.0319 0.2365
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0083 0.0772
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.0275 0.0273
Echinococcus granulosus lysine specific demethylase 5A 0.0127 0.0411 0.0409
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Echinococcus multilocularis insulin receptor 0.0615 0.2402 0.2401
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0052 0.0102 0.0721
Echinococcus granulosus lysine specific demethylase 6a 0.0028 0.0007 0.0005
Entamoeba histolytica heat shock protein 90, putative 0.0093 0.027 0.278
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0014
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0052 0.0102 0.01
Onchocerca volvulus Cathepsin L homolog 0.0113 0.0352 0.0924
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0008 0.0015
Brugia malayi Cathepsin L-like precursor 0.006 0.0135 0.0173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.0319 0.3149
Onchocerca volvulus 0.0113 0.0352 0.0924
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Schistosoma mansoni inositol monophosphatase 0.0036 0.0037 0.0035
Echinococcus multilocularis zinc finger protein 0.013 0.0424 0.0422
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.048 0.1852 0.7226
Brugia malayi mbt repeat family protein 0.0094 0.0275 0.0354
Schistosoma mansoni hypothetical protein 0.0123 0.0395 0.0393
Schistosoma mansoni hypothetical protein 0.1693 0.6808 0.6807
Schistosoma mansoni transcription factor btf3 0.0069 0.0172 0.017
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0087 0.0246 0.0887
Schistosoma mansoni tyrosine kinase 0.0615 0.2402 0.2401
Echinococcus multilocularis cysteine protease 0.0113 0.0352 0.035
Schistosoma mansoni ap endonuclease 0.0037 0.0041 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Echinococcus granulosus phd:f box containing protein 0.0028 0.0007 0.0005
Toxoplasma gondii histone lysine methyltransferase SET1 0.0351 0.1326 1
Brugia malayi hypothetical protein 0.0298 0.111 0.144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0066 0.0159 0.5834
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.037 0.1403 0.1401
Brugia malayi Bromodomain containing protein 0.0461 0.1776 0.2306
Echinococcus multilocularis SAM and MBT domain containing protein 0.0094 0.0275 0.0273
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0066 0.0159 0.0204
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0035 0.0212
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0041 0.0077
Echinococcus multilocularis jumonji domain containing 1A 0.0028 0.0007 0.0005
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Echinococcus multilocularis epidermal growth factor receptor 0.1911 0.7697 0.7697
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0066 0.0159 0.1156
Brugia malayi Endoplasmin precursor 0.0093 0.027 0.0348
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0083 0.0193
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0271 0.0997 0.0995
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.025 0.0914 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0076 0.0203 0.0201
Echinococcus granulosus zinc finger protein 0.013 0.0424 0.0422
Loa Loa (eye worm) hypothetical protein 0.0052 0.0102 0.0132
Echinococcus granulosus protein kinase c iota type 0.0286 0.1061 0.1059
Loa Loa (eye worm) hypothetical protein 0.0052 0.0102 0.0132
Echinococcus multilocularis cysteine protease 0.0113 0.0352 0.035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0102 0.0191
Schistosoma mansoni tyrosine kinase 0.0034 0.003 0.0028
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0102 0.01
Schistosoma mansoni tyrosine kinase 0.1911 0.7697 0.7697
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0052 0.0102 0.0132
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.015 0.0505 0.0656
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0172 0.0554
Loa Loa (eye worm) hypothetical protein 0.015 0.0503 0.0653
Schistosoma mansoni bromodomain containing protein 0.0391 0.149 0.1489
Brugia malayi chromobox protein homolog 3 0.0039 0.0049 0.0061
Giardia lamblia Cathepsin B precursor 0.0271 0.0997 1
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Echinococcus granulosus heat shock protein 0.0093 0.027 0.0268
Brugia malayi glutathione reductase 0.0189 0.0664 0.0861
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0058 0.0129 0.0127
Trypanosoma brucei Heat shock protein 83, putative 0.0093 0.027 0.2655
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0041 0.0262
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0432 0.1655 0.6448
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0052 0.0102 0.0721
Plasmodium vivax heat shock protein 86, putative 0.0093 0.027 0.1994
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0052 0.0102 0.01
Echinococcus granulosus twitchin 0.0037 0.0044 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0083 0.0193
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0373 0.1415 0.1413
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0011 0.0012
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0062 0.0143 0.0371
Loa Loa (eye worm) hypothetical protein 0.0229 0.0828 0.1075
Schistosoma mansoni cathepsin F (C01 family) 0.0113 0.0352 0.035
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0066 0.0159 0.1539
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.005 0.0094 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Trichomonas vaginalis heat shock protein, putative 0.0087 0.0246 0.0471
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0102 0.0318
Plasmodium falciparum heat shock protein 90, putative 0.0054 0.0111 0.0792
Schistosoma mansoni hypothetical protein 0.0091 0.0265 0.0263
Brugia malayi cathepsin F-like cysteine proteinase 0.0053 0.0108 0.0138
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0066 0.0159 0.5834
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0271 0.0997 1
Toxoplasma gondii heat shock protein HSP90 0.0093 0.027 0.1992
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0062 0.0143 0.1356
Leishmania major cathepsin L-like protease 0.0113 0.0352 0.3486
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0066 0.0159 0.1156
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0052 0.0339
Onchocerca volvulus Cathepsin F homolog 0.0113 0.0352 0.0924
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0113 0.0352 0.035
Entamoeba histolytica hypothetical protein 0.0072 0.0186 0.1844
Entamoeba histolytica cysteine proteinase, putative 0.006 0.0135 0.1272
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0067 0.0065
Trichomonas vaginalis helicase, putative 0.0039 0.0052 0.0095
Plasmodium falciparum basic transcription factor 3b, putative 0.0069 0.0172 0.1256
Giardia lamblia Cathepsin B precursor 0.0271 0.0997 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0083 0.0193
Plasmodium vivax serine-repeat antigen (SERA) 0.0052 0.0102 0.0721
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0615 0.2402 0.2401
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0039 0.005 0.0048
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0432 0.1655 0.6448
Loa Loa (eye worm) jmjC domain-containing protein 0.0181 0.063 0.0818
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Leishmania major cathepsin L-like protease 0.0113 0.0352 0.3486
Schistosoma mansoni microtubule-associated protein tau 0.136 0.5447 0.5446
Plasmodium falciparum cysteine proteinase falcipain 1 0.0105 0.0319 0.2365
Brugia malayi Fibronectin type III domain containing protein 0.0029 0.0011 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0632 0.063
Trypanosoma cruzi cruzipain precursor, putative 0.016 0.0545 0.1801
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0087 0.0246 0.0887
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0031 0.0017 0.008
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0102 0.01
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0052 0.0102 0.0721
Brugia malayi cathepsin L-like precursor 0.006 0.0135 0.0173
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0041 0.0075
Schistosoma mansoni inositol monophosphatase 0.0036 0.0037 0.0035
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.0319 0.3328
Schistosoma mansoni jumonji/arid domain-containing protein 0.0127 0.0411 0.0409
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0079 0.0215 0.0213
Loa Loa (eye worm) hypothetical protein 0.006 0.0135 0.0176
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0094 0.0275 0.0273
Loa Loa (eye worm) TK/FAK protein kinase 0.0819 0.3238 0.4206
Toxoplasma gondii exonuclease III APE 0.0037 0.0041 0.0262
Echinococcus granulosus histone acetyltransferase MYST2 0.0107 0.0328 0.0326
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Schistosoma mansoni hypothetical protein 0.0079 0.0215 0.0213
Trypanosoma brucei heat shock protein 90, putative 0.0093 0.027 0.2655
Echinococcus granulosus PHD finger protein rhinoceros 0.0088 0.0249 0.0247
Brugia malayi Papain family cysteine protease containing protein 0.0113 0.0352 0.0455
Echinococcus multilocularis muscleblind protein 0.015 0.0503 0.0501
Brugia malayi Cathepsin L-like precursor 0.0113 0.0352 0.0455
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0352 0.0675
Brugia malayi Cathepsin L-like precursor 0.0113 0.0352 0.0455
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0083 0.0772
Onchocerca volvulus Cathepsin L homolog 0.0052 0.0102 0.0264
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0083 0.0689
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0052 0.0102 0.0721
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0035 0.0212
Entamoeba histolytica cysteine protease, putative 0.0052 0.0102 0.0899
Leishmania major cathepsin L-like protease 0.016 0.0545 0.5436
Onchocerca volvulus 0.0113 0.0352 0.0924
Brugia malayi acetyltransferase, GNAT family protein 0.0159 0.0542 0.0702
Brugia malayi cathepsin B-like cysteine proteinase 0.076 0.2996 0.3891
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0047 0.0082 0.024
Trypanosoma brucei PAB1-binding protein , putative 0.0074 0.0196 0.1907
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0172 0.0224
Trypanosoma brucei transcription factor BTF3, putative 0.0069 0.0172 0.1672
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0288 0.1067 0.4098
Schistosoma mansoni bromodomain containing protein 0.0039 0.0051 0.0049
Schistosoma mansoni cathepsin s 0.0053 0.0108 0.0106
Schistosoma mansoni heat shock protein 0.0093 0.027 0.0268
Schistosoma mansoni cpg binding protein 0.0195 0.0688 0.0686
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Loa Loa (eye worm) fibroinase 0.0113 0.0352 0.0457
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0151 0.0193
Loa Loa (eye worm) hypothetical protein 0.0053 0.0108 0.014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Plasmodium falciparum glutathione reductase 0.0066 0.0159 0.1156
Giardia lamblia Cathepsin B precursor 0.0052 0.0102 0.0633
Loa Loa (eye worm) hypothetical protein 0.0247 0.09 0.1169
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0041 0.0205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0102 0.0191
Brugia malayi jmjC domain containing protein 0.0028 0.0007 0.0006
Schistosoma mansoni vesicular amine transporter 0.0029 0.0011 0.0009
Echinococcus multilocularis endoplasmin 0.0087 0.0246 0.0244
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0102 0.01
Schistosoma mansoni cathepsin F (C01 family) 0.0113 0.0352 0.035
Giardia lamblia Cathepsin B precursor 0.0052 0.0102 0.0633
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0172 0.0328
Loa Loa (eye worm) hypothetical protein 0.0052 0.0102 0.0132
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Schistosoma mansoni hypothetical protein 0.0079 0.0215 0.0213
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0151 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0102 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Loa Loa (eye worm) hypothetical protein 0.0113 0.0352 0.0457
Schistosoma mansoni tyrosine kinase 0.1029 0.4097 0.4095
Toxoplasma gondii PHD-finger domain-containing protein 0.0088 0.0249 0.1836
Echinococcus granulosus histone acetyltransferase KAT2B 0.0057 0.0124 0.0122
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0052 0.0102 0.0191
Echinococcus granulosus cathepsin l1 0.006 0.0135 0.0133
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0052 0.0102 0.01
Echinococcus granulosus GPCR family 2 0.0079 0.0215 0.0213
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Leishmania major basic transcription factor 3a, putative 0.0069 0.0172 0.1672
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0052 0.0102 0.0721
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0047 0.0082 0.008
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2655
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Loa Loa (eye worm) MBCTL1 0.0107 0.0328 0.0426
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0352 0.0675
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0037 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0181 0.0632 0.0819
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0052 0.0102 0.0633
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Giardia lamblia Cathepsin B precursor 0.0271 0.0997 1
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Trypanosoma cruzi trypanothione reductase, putative 0.0066 0.0159 0.051
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0061 0.0112
Giardia lamblia Cathepsin L precursor 0.0052 0.0102 0.0633
Giardia lamblia Cathepsin B precursor 0.0052 0.0102 0.0633
Loa Loa (eye worm) hypothetical protein 0.0251 0.0915 0.1189
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0082 0.0764
Plasmodium falciparum serine repeat antigen 4 0.0052 0.0102 0.0721
Treponema pallidum fructose-bisphosphate aldolase 0.0141 0.0467 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0102 0.0191
Loa Loa (eye worm) hypothetical protein 0.006 0.0135 0.0176
Echinococcus multilocularis cathepsin b 0.076 0.2996 0.2995
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.025 0.0914 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0099 0.0295 0.0964
Loa Loa (eye worm) hypothetical protein 0.076 0.2996 0.3893
Echinococcus multilocularis histone acetyltransferase MYST2 0.0107 0.0328 0.0326
Echinococcus granulosus cathepsin L 0.0105 0.0319 0.0317
Echinococcus granulosus endoplasmin 0.0087 0.0246 0.0244
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0049 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0082 0.0253
Plasmodium vivax glutathione reductase, putative 0.0189 0.0664 0.4987
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2655
Onchocerca volvulus 0.0174 0.0601 0.1581
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0101
Toxoplasma gondii heat shock protein 75, putative 0.0062 0.0143 0.103
Plasmodium falciparum phd finger protein, putative 0.0088 0.0249 0.1837
Trypanosoma cruzi cysteine peptidase, putative 0.0113 0.0352 0.1155
Echinococcus granulosus neuroglian 0.0037 0.0042 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Mycobacterium ulcerans heat shock protein 90 0.0087 0.0246 0.0841
Giardia lamblia Hypothetical protein 0.0052 0.0102 0.0633
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0083 0.0193
Brugia malayi cathepsin L-like cysteine proteinase 0.0052 0.0102 0.013
Trypanosoma cruzi cysteine proteinase, putative 0.0105 0.0319 0.1043
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0083 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Schistosoma mansoni methyl-cpg binding protein mbd 0.0102 0.0307 0.0305
Plasmodium falciparum serine repeat antigen 7 0.0052 0.0102 0.0721
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0196 0.0632
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0066 0.0159 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0319 0.0611
Giardia lamblia Cysteine protease 0.0052 0.0102 0.0633
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0067 0.0065
Loa Loa (eye worm) hypothetical protein 0.0052 0.0102 0.0132
Brugia malayi jmjC domain containing protein 0.0287 0.1063 0.1379
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0045
Brugia malayi Pre-SET motif family protein 0.0839 0.3319 0.431
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0352 0.0675
Echinococcus multilocularis cathepsin L 0.0052 0.0102 0.01
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0102 0.0191
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.0215 0.0213
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0043 0.0067 0.0087
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0047 0.0082 0.008
Schistosoma mansoni ap endonuclease 0.0037 0.0041 0.0039
Schistosoma mansoni myst-related protein 0.0032 0.0022 0.002
Plasmodium vivax endoplasmin, putative 0.0093 0.027 0.1994
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2655
Echinococcus multilocularis peregrin 0.0105 0.0321 0.0319
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0225 0.0812 0.081
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0041 0.0262
Treponema pallidum NADH oxidase 0.0066 0.0159 0.2768
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0052 0.0102 0.0721
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.076 0.2996 0.2995
Schistosoma mansoni chromobox protein 0.0069 0.0172 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0251 0.0915 0.1189
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0052 0.0102 0.013
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0037 0.0035
Trypanosoma cruzi cruzipain precursor, putative 0.0053 0.0108 0.0339
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0066 0.0159 0.0494
Echinococcus multilocularis PHD finger protein rhinoceros 0.0088 0.0249 0.0247
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0048 0.0086 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.051
Plasmodium falciparum serine repeat antigen 9 0.0052 0.0102 0.0721
Leishmania major hypothetical protein, conserved 0.0074 0.0196 0.1907
Loa Loa (eye worm) RNA binding protein 0.0063 0.0151 0.0196
Echinococcus multilocularis Immunoglobulin 0.0029 0.0011 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0102 0.0191
Echinococcus multilocularis protein kinase c epsilon type 0.0043 0.0067 0.0065
Echinococcus granulosus jumonji domain containing 1A 0.0028 0.0007 0.0005
Leishmania major cathepsin L-like protease 0.0113 0.0352 0.3486
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0033 0.0028 0.0026
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0047 0.0082 0.0253
Plasmodium vivax thioredoxin reductase, putative 0.0189 0.0664 0.4987
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0052 0.0102 0.0721
Schistosoma mansoni tyrosine kinase 0.1013 0.4028 0.4027
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0181 0.0632 0.063
Echinococcus granulosus geminin 0.1693 0.6808 0.6807
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0066 0.0159 0.1539
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0652 0.2554 1
Plasmodium falciparum thioredoxin reductase 0.0189 0.0664 0.4987
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0186 0.0184
Loa Loa (eye worm) hypothetical protein 0.0268 0.0987 0.1282
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0251 0.0915 0.1187
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0088 0.0249 0.0247
Plasmodium falciparum endoplasmin, putative 0.0067 0.0166 0.1207
Schistosoma mansoni myst-related protein 0.0032 0.0022 0.002
Plasmodium falciparum glutathione reductase 0.0189 0.0664 0.4987
Brugia malayi cathepsin Z-like cysteine proteinase 0.0052 0.0102 0.013
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0102 0.01
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0066 0.0159 0.0494
Loa Loa (eye worm) hypothetical protein 0.0225 0.0812 0.1055
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0083 0.0772
Plasmodium falciparum serine repeat antigen 2 0.0052 0.0102 0.0721
Echinococcus granulosus JmjC domain containing protein 4 0.0028 0.0007 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0052 0.0102 0.0191
Brugia malayi Calcitonin receptor-like protein seb-1 0.0251 0.0915 0.1187
Schistosoma mansoni cell adhesion molecule 0.0039 0.005 0.0048
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0151 0.0149
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Trichomonas vaginalis mercuric reductase, putative 0.0066 0.0159 0.0302
Onchocerca volvulus 0.006 0.0135 0.0352
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0041 0.0116
Giardia lamblia PHD finger protein 15 0.0088 0.0249 0.2173
Giardia lamblia Heat shock protein HSP 90-alpha 0.0079 0.0215 0.1817
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0051 0.0337
Loa Loa (eye worm) hypothetical protein 0.0074 0.0196 0.0254
Trypanosoma cruzi cysteine protease, putative 0.0105 0.0319 0.1043
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0041 0.0054
Echinococcus granulosus Protein kinase C brain isozyme 0.0043 0.0067 0.0065
Echinococcus granulosus tumor protein p63 0.0339 0.1274 0.1272
Trypanosoma cruzi heat shock protein 85, putative 0.0093 0.027 0.0879
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0652 0.2554 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0083 0.0242
Brugia malayi jmjC domain containing protein 0.0028 0.0007 0.0006
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0215 0.0768 0.0766
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Schistosoma mansoni cathepsin B (C01 family) 0.0052 0.0102 0.01
Toxoplasma gondii NAC domain-containing protein 0.0069 0.0172 0.1255
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0107 0.0328 0.0326
Entamoeba histolytica hypothetical protein 0.0072 0.0186 0.1844
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0186 0.0184
Schistosoma mansoni phd/f-box containing protein 0.0028 0.0007 0.0005
Loa Loa (eye worm) transcription factor SMAD2 0.0352 0.1327 0.1724
Plasmodium falciparum heat shock protein 90, putative 0.0351 0.1325 1
Echinococcus multilocularis neuropeptide s receptor 0.0456 0.1754 0.1753
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0141 0.0467 0.4992
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.048 0.1852 0.7226
Brugia malayi PHD-finger family protein 0.005 0.0095 0.0121
Echinococcus multilocularis protein tyrosine kinase 0.081 0.3199 0.3198
Echinococcus granulosus jumonji domain containing protein 0.0122 0.0389 0.0387
Echinococcus granulosus insulin receptor 0.0615 0.2402 0.2401
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.0319 0.3328
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.005 0.0094 0.0092
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0545 0.5436
Onchocerca volvulus 0.0113 0.0352 0.0924
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0083 0.0242
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.051
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0105 0.0319 0.0317
Brugia malayi Heterochromatin protein 1 0.0069 0.0172 0.0221
Giardia lamblia Grp94/Hsp90 0.0087 0.0246 0.2146
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0396 0.0394
Loa Loa (eye worm) TK/INSR protein kinase 0.0615 0.2402 0.3121
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0052 0.0102 0.0191
Schistosoma mansoni tyrosine kinase 0.1013 0.4028 0.4027
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Loa Loa (eye worm) hypothetical protein 0.0052 0.0102 0.0132
Echinococcus granulosus microtubule associated protein 2 0.136 0.5447 0.5446
Schistosoma mansoni tyrosine kinase 0.1029 0.4097 0.4095
Schistosoma mansoni atypical protein kinase C 0.0304 0.1134 0.1132
Loa Loa (eye worm) hypothetical protein 0.0171 0.0591 0.0768
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0268 0.0984 0.3801
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0102 0.0191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0352 0.0675
Brugia malayi Immunoglobulin I-set domain containing protein 0.0491 0.1895 0.246
Echinococcus granulosus muscleblind protein 0.015 0.0503 0.0501
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0045
Echinococcus granulosus cathepsin b 0.076 0.2996 0.2995
Loa Loa (eye worm) hypothetical protein 0.0079 0.0215 0.028
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0151 0.0149
Echinococcus multilocularis jumonji domain containing protein 0.0122 0.0389 0.0387
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0033 0.0024 0.0022
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0007 0.0009
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0306
Brugia malayi MH2 domain containing protein 0.0352 0.1327 0.1722
Schistosoma mansoni hypothetical protein 0.0079 0.0215 0.0213
Brugia malayi Protein kinase domain containing protein 0.0819 0.3238 0.4205
Trichomonas vaginalis heat shock protein, putative 0.0067 0.0166 0.0315
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0058 0.0129 0.0127
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0287 0.1063 0.1061
Entamoeba histolytica cysteine protease, putative 0.0105 0.0319 0.3328
Leishmania major cathepsin L-like protease 0.0113 0.0352 0.3486
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0105 0.0319 0.0317
Echinococcus granulosus cpg binding protein 0.0195 0.0688 0.0686
Echinococcus multilocularis protein kinase c iota type 0.0286 0.1061 0.1059
Loa Loa (eye worm) heat shock protein 75 0.0062 0.0143 0.0185
Onchocerca volvulus 0.0113 0.0352 0.0924
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2655
Onchocerca volvulus 0.0298 0.111 0.2925
Loa Loa (eye worm) hypothetical protein 0.0039 0.0051 0.0066
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0107 0.0328 0.0423
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0102 0.013
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0159 0.0542 0.054
Brugia malayi Hsp90 protein 0.0062 0.0143 0.0183
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2655
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0083 0.0242
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Echinococcus granulosus defective proboscis extension response 0.0029 0.0011 0.0009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.037 0.1403 0.1401
Loa Loa (eye worm) acetyltransferase 0.0159 0.0542 0.0704
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0057 0.0124 0.0885
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0352 0.0675

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.2 nM Growth inhibition of human mammary carcinoma (MCF-7) cell line ChEMBL. 9022793
IC50 (functional) = 0.2 nM Growth inhibition of human mammary carcinoma (MCF-7) cell line ChEMBL. 9022793
IC50 (functional) = 0.5 nM Growth inhibition of human non-small-lung carcinoma (A549) cell line ChEMBL. 9022793
IC50 (functional) = 0.5 nM Growth inhibition of human non-small-lung carcinoma (A549) cell line ChEMBL. 9022793
IC50 (functional) = 0.6 nM Growth inhibition of human colon carcinoma (HT-29) cell line ChEMBL. 9022793
IC50 (functional) = 0.6 nM Growth inhibition of human colon carcinoma (HT-29) cell line ChEMBL. 9022793
IC50 (functional) = 0.7 nM Growth inhibition of human ovarian carcinoma (A121) cell line ChEMBL. 9022793
IC50 (functional) = 0.7 nM Growth inhibition of human ovarian carcinoma (A121) cell line ChEMBL. 9022793
IC50 (functional) = 26 nM Growth inhibition of human mammary carcinoma 180 fold resistant to doxorubicin (MCF-7-R) cell line ChEMBL. 9022793
IC50 (functional) = 26 nM Growth inhibition of human mammary carcinoma 180 fold resistant to doxorubicin (MCF-7-R) cell line ChEMBL. 9022793
Ratio (functional) = 130 Ratio of growth inhibition (IC50) of MCF7-R / MCF-7 cell lines ChEMBL. 9022793

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 9022793

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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