Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | acetyl-CoA carboxylase alpha | Starlite/ChEMBL | References |
Homo sapiens | acetyl-CoA carboxylase beta | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0744 | 0.9605 | 0.96 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0203 | 0.2106 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.006 | 0.0133 | 0.5 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0077 | 0.0367 | 0.0448 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase alpha chain | 0.0077 | 0.0367 | 0.0448 |
Plasmodium falciparum | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0147 | 0.1329 | 0.5 |
Onchocerca volvulus | 0.006 | 0.0133 | 0.5 | |
Schistosoma mansoni | pyruvate carboxylase | 0.0077 | 0.0367 | 0.0448 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.0196 | 0.2007 | 0.1899 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0126 | 0.1036 | 1 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.0196 | 0.2007 | 0.1978 |
Mycobacterium ulcerans | bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 | 0.0077 | 0.0367 | 0.5 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0203 | 0.2106 | 1 |
Mycobacterium ulcerans | pyruvate carboxylase | 0.0077 | 0.0367 | 0.5 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0077 | 0.0367 | 0.0448 |
Onchocerca volvulus | Bile acid receptor homolog | 0.006 | 0.0133 | 0.5 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0203 | 0.2106 | 1 |
Mycobacterium tuberculosis | Probable pyruvate carboxylase Pca (pyruvic carboxylase) | 0.0077 | 0.0367 | 0.5 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0077 | 0.0367 | 0.1741 |
Wolbachia endosymbiont of Brugia malayi | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.0077 | 0.0367 | 0.5 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 | 0.0077 | 0.0367 | 0.5 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0376 | 0.4506 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0436 | 0.5343 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0436 | 0.5343 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0376 | 0.4506 | 0.8394 |
Loa Loa (eye worm) | hypothetical protein | 0.0741 | 0.9558 | 0.995 |
Chlamydia trachomatis | biotin carboxylase | 0.007 | 0.0268 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0744 | 0.9605 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0436 | 0.5343 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.006 | 0.0133 | 0.5 |
Plasmodium vivax | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0147 | 0.1329 | 0.5 |
Mycobacterium leprae | Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) | 0.0077 | 0.0367 | 0.5 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0077 | 0.0367 | 0.1741 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0744 | 0.9605 | 0.96 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0376 | 0.4506 | 0.8394 |
Echinococcus granulosus | propionyl coenzyme A carboxylase alpha chain | 0.0077 | 0.0367 | 0.0534 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0203 | 0.2106 | 0.3786 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 | 0.0077 | 0.0367 | 0.5 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0203 | 0.2106 | 0.3786 |
Mycobacterium tuberculosis | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie | 0.0077 | 0.0367 | 0.5 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0203 | 0.2106 | 0.451 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0203 | 0.2106 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.