Detailed information for compound 156953

Basic information

Technical information
  • TDR Targets ID: 156953
  • Name: N-[2-[4-[[3-butyl-5-oxo-1-[2-(trifluoromethyl )phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phe nyl]sulfonyl-3-cyclopentylpropanamide
  • MW: 654.742 | Formula: C34H37F3N4O4S
  • H donors: 1 H acceptors: 4 LogP: 7.73 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCc1nn(c(=O)n1Cc1ccc(cc1)c1ccccc1S(=O)(=O)NC(=O)CCC1CCCC1)c1ccccc1C(F)(F)F
  • InChi: 1S/C34H37F3N4O4S/c1-2-3-16-31-38-41(29-14-8-7-13-28(29)34(35,36)37)33(43)40(31)23-25-17-20-26(21-18-25)27-12-6-9-15-30(27)46(44,45)39-32(42)22-19-24-10-4-5-11-24/h6-9,12-15,17-18,20-21,24H,2-5,10-11,16,19,22-23H2,1H3,(H,39,42)
  • InChiKey: NIOFBGYJFARBSF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[2-[4-[[3-butyl-5-oxo-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phenyl]sulfonyl-3-cyclopentyl-propanamide
  • N-[2-[4-[[3-butyl-5-keto-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phenyl]sulfonyl-3-cyclopentyl-propionamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Oryctolagus cuniculus Angiotensin II type 1a (AT-1a) receptor Starlite/ChEMBL References
Rattus norvegicus Angiotensin II type 2 (AT-2) receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis neuropeptide receptor Angiotensin II type 2 (AT-2) receptor   363 aa 308 aa 21.4 %
Onchocerca volvulus Angiotensin II type 1a (AT-1a) receptor   359 aa 341 aa 23.2 %
Echinococcus granulosus neuropeptide receptor Angiotensin II type 2 (AT-2) receptor   363 aa 306 aa 22.2 %
Echinococcus granulosus allatostatin A receptor Angiotensin II type 2 (AT-2) receptor   363 aa 340 aa 24.1 %
Brugia malayi putative neuropeptide receptor NPR1 Angiotensin II type 1a (AT-1a) receptor   359 aa 295 aa 27.1 %
Echinococcus granulosus tm gpcr rhodopsin Angiotensin II type 1a (AT-1a) receptor   359 aa 306 aa 21.9 %
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor Angiotensin II type 1a (AT-1a) receptor   359 aa 346 aa 18.2 %
Echinococcus granulosus growth hormone secretagogue receptor type 1 Angiotensin II type 1a (AT-1a) receptor   359 aa 342 aa 22.2 %
Brugia malayi ORL1-like opioid receptor Angiotensin II type 1a (AT-1a) receptor   359 aa 333 aa 21.3 %
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor Angiotensin II type 2 (AT-2) receptor   363 aa 398 aa 18.1 %
Onchocerca volvulus Angiotensin II type 1a (AT-1a) receptor   359 aa 399 aa 25.3 %
Echinococcus multilocularis G-protein coupled receptor, putative Angiotensin II type 1a (AT-1a) receptor   359 aa 307 aa 22.5 %
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor Angiotensin II type 1a (AT-1a) receptor   359 aa 364 aa 23.1 %
Loa Loa (eye worm) hypothetical protein Angiotensin II type 1a (AT-1a) receptor   359 aa 308 aa 27.3 %
Schistosoma japonicum Rhodopsin, putative Angiotensin II type 2 (AT-2) receptor   363 aa 341 aa 22.0 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Angiotensin II type 2 (AT-2) receptor   363 aa 310 aa 23.5 %
Schistosoma mansoni opsin-like receptor Angiotensin II type 1a (AT-1a) receptor   359 aa 299 aa 25.1 %
Echinococcus multilocularis allatostatin A receptor Angiotensin II type 2 (AT-2) receptor   363 aa 342 aa 24.6 %
Loa Loa (eye worm) neuropeptide F receptor Angiotensin II type 2 (AT-2) receptor   363 aa 356 aa 23.3 %
Onchocerca volvulus Angiotensin II type 2 (AT-2) receptor   363 aa 306 aa 22.5 %
Schistosoma mansoni adenoreceptor Angiotensin II type 2 (AT-2) receptor   363 aa 328 aa 22.0 %
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Angiotensin II type 1a (AT-1a) receptor   359 aa 306 aa 21.9 %
Echinococcus granulosus pyroglutamylated rfamide peptide receptor Angiotensin II type 2 (AT-2) receptor   363 aa 398 aa 18.3 %
Echinococcus granulosus thyrotropin releasing hormone receptor Angiotensin II type 2 (AT-2) receptor   363 aa 308 aa 22.1 %
Onchocerca volvulus E3 ubiquitin-protein ligase rpm-1 homolog Angiotensin II type 1a (AT-1a) receptor   359 aa 328 aa 20.7 %
Onchocerca volvulus Angiotensin II type 1a (AT-1a) receptor   359 aa 313 aa 25.6 %
Loa Loa (eye worm) hypothetical protein Angiotensin II type 1a (AT-1a) receptor   359 aa 335 aa 23.0 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Angiotensin II type 1a (AT-1a) receptor   359 aa 325 aa 20.9 %
Brugia malayi GnHR receptor homolog Angiotensin II type 1a (AT-1a) receptor   359 aa 364 aa 20.3 %
Onchocerca volvulus Angiotensin II type 1a (AT-1a) receptor   359 aa 296 aa 23.0 %
Schistosoma mansoni peptide (allatostatin)-like receptor Angiotensin II type 2 (AT-2) receptor   363 aa 364 aa 20.9 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Angiotensin II type 2 (AT-2) receptor   363 aa 308 aa 21.8 %
Onchocerca volvulus Angiotensin II type 2 (AT-2) receptor   363 aa 305 aa 21.6 %
Onchocerca volvulus Angiotensin II type 2 (AT-2) receptor   363 aa 311 aa 23.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus inositol monophosphatase 1 0.0073 0.0203 0.02
Echinococcus granulosus cysteine protease 0.0103 0.0319 0.0316
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0065
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0027 0.0028
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0163 0.0555 0.0552
Loa Loa (eye worm) heat shock protein 75 0.0065 0.0168 0.0219
Loa Loa (eye worm) transcription factor SMAD2 0.0241 0.0862 0.115
Brugia malayi cathepsin F-like cysteine proteinase 0.0052 0.012 0.0153
Onchocerca volvulus 0.0036 0.0054 0.0103
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0051 0.0113 0.0776
Schistosoma mansoni myst-related protein 0.0035 0.0051 0.0048
Onchocerca volvulus 0.0441 0.1652 0.35
Onchocerca volvulus 0.0024 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Schistosoma mansoni zinc finger protein 0.0024 0.0008 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0152 0.0588
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0033 0.007
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0567 0.2146 0.2144
Schistosoma mansoni PHD zinc finger protein XAP135-related 0.0024 0.0008 0.0005
Plasmodium vivax heat shock protein 90, putative 0.0065 0.0168 0.1182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0907 0.0904
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0111 0.035 0.0744
Schistosoma mansoni hypothetical protein 0.0109 0.0343 0.034
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0061 0.0154 0.02
Schistosoma mansoni methyl-cpg binding protein mbd 0.0122 0.0393 0.039
Echinococcus granulosus jumonji domain containing 1A 0.0029 0.0027 0.0023
Echinococcus granulosus cathepsin L 0.0051 0.0113 0.011
Toxoplasma gondii NADPH-glutathione reductase 0.0051 0.0116 0.0798
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0018 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Plasmodium falciparum serine repeat antigen 1 0.0051 0.0113 0.0776
Schistosoma mansoni hypothetical protein 0.0082 0.0235 0.0232
Echinococcus granulosus GPCR family 2 0.0082 0.0235 0.0232
Brugia malayi hypothetical protein 0.0029 0.0027 0.0029
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0041 0.0048
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0026 0.0017 0.0015
Entamoeba histolytica hypothetical protein 0.0073 0.0203 0.2213
Brugia malayi conserved hypotetical protein 0.0029 0.0027 0.0029
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0011 0.0008
Trypanosoma cruzi ISWI complex protein 0.0109 0.0343 0.1181
Echinococcus multilocularis epidermal growth factor receptor 0.1913 0.745 0.7449
Onchocerca volvulus Matrilysin homolog 0.0036 0.0054 0.0103
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0027 0.0066
Onchocerca volvulus 0.0434 0.1622 0.3435
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0051 0.0113 0.121
Echinococcus multilocularis cathepsin L 0.0051 0.0113 0.011
Echinococcus multilocularis JmjC domain containing protein 4 0.0029 0.0027 0.0023
Schistosoma mansoni tyrosine kinase 0.1913 0.745 0.7449
Brugia malayi Matrixin family protein 0.0036 0.0054 0.0065
Schistosoma mansoni zinc finger protein 0.0153 0.0518 0.0515
Loa Loa (eye worm) hypothetical protein 0.0258 0.0929 0.1241
Brugia malayi hypothetical protein 0.0032 0.0041 0.0048
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.0119 0.0253
Echinococcus granulosus cathepsin L cysteine proteinase 0.0111 0.035 0.0347
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0051 0.0113 0.0776
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0103 0.0319 0.1095
Brugia malayi Immunoglobulin I-set domain containing protein 0.0489 0.1841 0.2465
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0154 0.02
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0105 0.0326 0.1121
Echinococcus multilocularis neuroglian 0.0037 0.0058 0.0055
Plasmodium vivax endoplasmin, putative 0.0097 0.0297 0.2129
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.004 0.0073 0.0155
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.006 0.015 0.1045
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus granulosus cathepsin L cysteine protease 0.0103 0.0319 0.0316
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Plasmodium falciparum heat shock protein 90 0.0097 0.0297 0.2129
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0376 0.1394 0.5565
Echinococcus granulosus neuropeptide s receptor 0.0466 0.1748 0.1746
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.035 0.3869
Schistosoma mansoni hypothetical protein 0.1732 0.6737 0.6736
Toxoplasma gondii LsmAD domain-containing protein 0.0075 0.0211 0.1493
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Schistosoma mansoni cathepsin C 0.0051 0.0113 0.011
Loa Loa (eye worm) hypothetical protein 0.0082 0.0235 0.0309
Echinococcus granulosus cathepsin l cysteine peptidase 0.0111 0.035 0.0347
Trypanosoma brucei heat shock protein 90, putative 0.0097 0.0297 0.3038
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0029 0.0029 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0473 0.047
Brugia malayi nuclear hormone receptor 0.0061 0.0154 0.02
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Schistosoma mansoni hypothetical protein 0.0176 0.0608 0.0605
Giardia lamblia Hypothetical protein 0.0051 0.0113 0.0495
Echinococcus multilocularis phd finger protein 10 0.0024 0.0008 0.0005
Plasmodium vivax serine-repeat antigen (SERA) 0.0051 0.0113 0.0776
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0152 0.0149
Brugia malayi Bromodomain containing protein 0.0548 0.2074 0.2778
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0051 0.0113 0.024
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0376 0.1394 0.5565
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0051 0.0116 0.0798
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Giardia lamblia Cysteine protease 0.0051 0.0113 0.0495
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Echinococcus multilocularis ecdysone induced protein 78C 0.0061 0.0154 0.0151
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0011 0.0012
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0265 0.0959 1
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0154 0.0151
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0278 0.1011 0.1008
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0061 0.0154 0.02
Treponema pallidum heat shock protein 90 0.0091 0.0273 0.4403
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0035 0.0053 0.0049
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Echinococcus multilocularis remodeling and spacing factor 1 0.0024 0.0008 0.0005
Brugia malayi TAR-binding protein 0.0252 0.0907 0.1211
Brugia malayi RNA binding protein 0.0252 0.0907 0.1211
Echinococcus granulosus lamin 0.0026 0.0018 0.0015
Loa Loa (eye worm) TK protein kinase 0.0024 0.0009 0.0005
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Echinococcus multilocularis tar DNA binding protein 0.0252 0.0907 0.0904
Onchocerca volvulus Matrilysin homolog 0.0079 0.0225 0.0466
Entamoeba histolytica hypothetical protein 0.0051 0.0113 0.121
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0051 0.0116 0.1138
Giardia lamblia Heat shock protein HSP 90-alpha 0.0083 0.0242 0.1936
Schistosoma mansoni hypothetical protein 0.0073 0.0203 0.02
Brugia malayi Inositol-1 0.0073 0.0203 0.0265
Toxoplasma gondii hypothetical protein 0.0052 0.0119 0.0815
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Trichomonas vaginalis heat shock protein, putative 0.0091 0.0273 0.058
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0027 0.0024
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0028 0.0148
Onchocerca volvulus 0.0033 0.0046 0.0085
Giardia lamblia Encystation-specific protease 0.0051 0.0113 0.0495
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0027 0.0029
Echinococcus multilocularis Immunoglobulin 0.0029 0.0029 0.0026
Schistosoma mansoni hypothetical protein 0.0029 0.0028 0.0025
Echinococcus granulosus PHD finger protein rhinoceros 0.0089 0.0263 0.026
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0152 0.1063
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0061 0.0154 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0113 0.024
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0029 0.0027 0.0137
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0091 0.0273 0.2809
Echinococcus granulosus histone acetyltransferase KAT2B 0.006 0.015 0.0147
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0027 0.0024
Trypanosoma cruzi cruzipain precursor, putative 0.0157 0.0532 0.1845
Giardia lamblia Fructose-bisphosphate aldolase 0.0142 0.0473 0.4539
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0152 0.0149
Brugia malayi cathepsin L-like cysteine proteinase 0.0051 0.0113 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0113 0.0145
Echinococcus multilocularis zinc finger protein 0.0153 0.0518 0.0515
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2848 0.2846
Giardia lamblia Cathepsin L-like protease 0.0051 0.0113 0.0495
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0153
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.0319 0.0316
Echinococcus granulosus insulin receptor 0.0615 0.2338 0.2336
Echinococcus multilocularis muscleblind protein 0.0151 0.0508 0.0505
Brugia malayi Steroid receptor seven-up type 2 0.0061 0.0154 0.02
Echinococcus multilocularis histone acetyltransferase myst4 0.0024 0.0008 0.0005
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0027 0.0024
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0032 0.0041 0.0038
Echinococcus multilocularis TAF3 RNA polymerase II, TATA box binding protein 0.0024 0.0008 0.0005
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0258 0.0929 0.1241
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Echinococcus granulosus PHD finger protein 14 0.0024 0.0008 0.0005
Brugia malayi jmjC domain containing protein 0.0029 0.0027 0.0028
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0047 0.0044
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0061 0.0154 0.02
Plasmodium falciparum thioredoxin reductase 0.0051 0.0116 0.0798
Brugia malayi PHD-finger family protein 0.0191 0.0668 0.089
Trypanosoma cruzi Heat shock protein 83, putative 0.0097 0.0297 0.1017
Echinococcus granulosus histone acetyltransferase MYST2 0.0163 0.0555 0.0552
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0113 0.024
Onchocerca volvulus 0.0111 0.035 0.0733
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0029 0.0032
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.0116 0.0381
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0028
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.006 0.015 0.1045
Onchocerca volvulus Matrix metalloproteinase homolog 0.0079 0.0225 0.0466
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Leishmania major hypothetical protein, conserved 0.0109 0.0343 0.3544
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0038 0.0034
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0154 0.0151
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Plasmodium vivax vivapain-2 0.0111 0.035 0.2522
Schistosoma mansoni jumonji domain containing protein 0.0029 0.0027 0.0023
Echinococcus multilocularis epidermal growth factor receptor 0.1031 0.3974 0.3972
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0089 0.0263 0.026
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0059 0.0147 0.0144
Brugia malayi glutathione reductase 0.0148 0.0498 0.0661
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0319 0.3517
Toxoplasma gondii NAC domain-containing protein 0.0071 0.0192 0.1359
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0033 0.0044 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0111 0.035 0.0744
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Plasmodium vivax glutathione reductase, putative 0.0148 0.0498 0.3607
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0051 0.0113 0.024
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0051 0.0116 0.0149
Loa Loa (eye worm) hypothetical protein 0.0059 0.0145 0.0187
Brugia malayi Matrixin family protein 0.0036 0.0054 0.0065
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0065 0.0168 0.0165
Plasmodium vivax basic transcription factor 3b, putative 0.0071 0.0192 0.1359
Trichomonas vaginalis heat shock protein, putative 0.0083 0.0242 0.0513
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0027 0.0029
Schistosoma mansoni hypothetical protein 0.0024 0.0008 0.0005
Echinococcus multilocularis heat shock protein 0.0097 0.0297 0.0294
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0051 0.0113 0.0145
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0027 0.0024
Loa Loa (eye worm) cathepsin B 0.0265 0.0959 0.1281
Giardia lamblia Cathepsin B precursor 0.0265 0.0959 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0026 0.0017 0.0036
Echinococcus multilocularis Zinc finger, DBF type 0.0024 0.0008 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Echinococcus granulosus roundabout 2 0.0046 0.0096 0.0093
Loa Loa (eye worm) hypothetical protein 0.025 0.0897 0.1197
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0615 0.2338 0.2336
Brugia malayi MH2 domain containing protein 0.0241 0.0862 0.115
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0027 0.0046
Loa Loa (eye worm) jmjC domain-containing protein 0.0183 0.0635 0.0845
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0061 0.0154 0.0151
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0171 0.0587 0.0584
Echinococcus multilocularis inositol monophosphatase 1 0.0073 0.0203 0.02
Loa Loa (eye worm) hypothetical protein 0.005 0.0111 0.0141
Loa Loa (eye worm) CHromoDomain protein family member 0.0035 0.0053 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2848 0.2846
Giardia lamblia PHD finger protein 15 0.0089 0.0263 0.2176
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0051 0.0116 0.0113
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0113 0.0145
Brugia malayi Latrophilin receptor protein 2 0.0082 0.0235 0.0309
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Giardia lamblia Cathepsin B precursor 0.0051 0.0113 0.0495
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0154 0.0151
Brugia malayi hypothetical protein 0.0032 0.0041 0.0048
Trichomonas vaginalis inhibitor of growth, putative 0.0024 0.0008 0.0017
Schistosoma mansoni nephrin 0.0037 0.0058 0.0055
Plasmodium vivax heat shock protein, putative 0.0369 0.1365 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0319 0.3517
Echinococcus multilocularis muscleblind protein 1 0.0151 0.0508 0.0505
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0008 0.0003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0052 0.012 0.0153
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0113 0.0495
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0052 0.012 0.0153
Echinococcus multilocularis histone acetyltransferase myst3 0.0024 0.0008 0.0005
Echinococcus multilocularis lysine specific demethylase 6a 0.0029 0.0027 0.0023
Echinococcus multilocularis chromobox protein 1 0.0069 0.0187 0.0184
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0059 0.0147 0.1465
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Loa Loa (eye worm) TAR-binding protein 0.0252 0.0907 0.1211
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Onchocerca volvulus 0.0029 0.0027 0.0046
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0028
Toxoplasma gondii preprocathepsin c precursor, putative 0.0051 0.0113 0.0776
Loa Loa (eye worm) cysteine protease 0.0111 0.035 0.0463
Schistosoma mansoni hypothetical protein 0.0082 0.0235 0.0232
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0113 0.024
Mycobacterium tuberculosis Probable dehydrogenase 0.0338 0.1245 0.497
Brugia malayi nuclear receptor NHR-88 0.0061 0.0154 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0473 0.047
Brugia malayi Bromodomain containing protein 0.0109 0.0343 0.0454
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.025 0.0897 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0089 0.0263 0.1879
Entamoeba histolytica hypothetical protein 0.0073 0.0203 0.2213
Brugia malayi PHD-finger family protein 0.0024 0.0008 0.0003
Brugia malayi Pre-SET motif family protein 0.0157 0.0532 0.0707
Schistosoma mansoni RAR-like nuclear receptor 0.0061 0.0154 0.0151
Brugia malayi hypothetical protein 0.0024 0.0008 0.0003
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.0116 0.1138
Brugia malayi nuclear receptor NHR-88 0.0029 0.0027 0.0029
Trypanosoma cruzi heat shock protein 85, putative 0.0097 0.0297 0.1017
Schistosoma mansoni tyrosine kinase 0.1031 0.3974 0.3972
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0376 0.1394 0.5565
Schistosoma mansoni requim req/dpf2 0.0024 0.0008 0.0005
Echinococcus granulosus microtubule associated protein 2 0.1364 0.5286 0.5284
Schistosoma mansoni tyrosine kinase 0.1014 0.3908 0.3906
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0338 0.1245 0.497
Loa Loa (eye worm) MBCTL1 0.0163 0.0555 0.0738
Giardia lamblia Cathepsin B precursor 0.0265 0.0959 1
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Schistosoma mansoni tyrosine kinase 0.0808 0.3094 0.3092
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0052 0.0121 0.0117
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0111 0.035 0.0347
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0211 0.0713
Echinococcus granulosus endoplasmin 0.0091 0.0273 0.027
Echinococcus granulosus polycomb protein SCMH1 0.0143 0.0477 0.0474
Echinococcus multilocularis lysine specific demethylase 5A 0.0107 0.0336 0.0333
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Trypanosoma brucei transcription factor BTF3, putative 0.0071 0.0192 0.194
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0048
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0113 0.0145
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0065
Trichomonas vaginalis mercuric reductase, putative 0.0051 0.0116 0.0247
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Echinococcus multilocularis uro adherence factor A 0.0024 0.0008 0.0005
Onchocerca volvulus Cathepsin L homolog 0.0111 0.035 0.0733
Schistosoma mansoni dpf3 0.0024 0.0008 0.0005
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0111 0.0107
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0065 0.0168 0.0346
Schistosoma mansoni hypothetical protein 0.0024 0.0008 0.0005
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0051 0.0116 0.0444
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.012 0.0393
Loa Loa (eye worm) TK/ROR protein kinase 0.0024 0.0009 0.0005
Brugia malayi Bromodomain associated family protein 0.0024 0.0008 0.0003
Loa Loa (eye worm) hypothetical protein 0.0441 0.1652 0.2212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0078 0.0155
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0018 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0051 0.0113 0.024
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0027 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0157 0.0532 0.1845
Echinococcus granulosus histone acetyltransferase myst4 0.0024 0.0008 0.0005
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Entamoeba histolytica hypothetical protein 0.0073 0.0203 0.2213
Entamoeba histolytica cysteine protease, putative 0.0111 0.035 0.3869
Brugia malayi tailless protein 0.0029 0.0027 0.0029
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0039 0.0067 0.0063
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.0319 0.0316
Leishmania major trypanothione reductase 0.0148 0.0498 0.5161
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0113 0.024
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0038 0.0062 0.0077
Brugia malayi hypothetical protein 0.0029 0.0027 0.0029
Mycobacterium ulcerans hydrolase 0.0043 0.0085 0.0317
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0011 0.0008
Echinococcus multilocularis mixed lineage leukemia protein mll 0.005 0.0112 0.0109
Brugia malayi Muscleblind-like protein 0.0151 0.0508 0.0675
Plasmodium vivax hypothetical protein, conserved 0.004 0.0071 0.0466
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Plasmodium falciparum serine repeat antigen 2 0.0051 0.0113 0.0776
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0473 0.047
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0061 0.0154 0.0151
Entamoeba histolytica hypothetical protein 0.0025 0.0011 0.0067
Loa Loa (eye worm) hypothetical protein 0.0441 0.1652 0.2212
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Toxoplasma gondii thioredoxin reductase 0.0148 0.0498 0.3607
Brugia malayi hypothetical protein 0.0461 0.1731 0.2317
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0051 0.0116 0.0798
Schistosoma mansoni phd/f-box containing protein 0.0029 0.0027 0.0023
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0036 0.0054 0.0051
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0011 0.0008
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0029 0.0029 0.0026
Trichomonas vaginalis set domain proteins, putative 0.1218 0.4711 1
Echinococcus granulosus cathepsin b 0.0745 0.2848 0.2846
Brugia malayi Endoplasmin precursor 0.0097 0.0297 0.0392
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0051 0.0113 0.0776
Echinococcus multilocularis PHD and RING finger domain containing protein 1 0.0024 0.0008 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Loa Loa (eye worm) TK/INSR protein kinase 0.0615 0.2338 0.3133
Trypanosoma cruzi cysteine peptidase, putative 0.0111 0.035 0.1205
Toxoplasma gondii cathepsin CPL 0.0111 0.035 0.2522
Echinococcus granulosus epidermal growth factor receptor 0.1031 0.3974 0.3972
Schistosoma mansoni sex comb on midleg homolog 0.0143 0.0477 0.0474
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0061 0.0154 0.0151
Plasmodium falciparum zinc finger protein, putative 0.0035 0.0051 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0103 0.0319 0.0677
Brugia malayi Pre-SET motif family protein 0.1071 0.413 0.5541
Onchocerca volvulus Cathepsin F homolog 0.0111 0.035 0.0733
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0143 0.0477 0.1001
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0051 0.0116 0.5
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0029 0.0027 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0113 0.024
Schistosoma mansoni retinoic acid receptor RXR 0.0061 0.0154 0.0151
Loa Loa (eye worm) hypothetical protein 0.0461 0.1731 0.2317
Leishmania major cathepsin L-like protease 0.0111 0.035 0.3616
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0163 0.0555 0.0738
Trypanosoma cruzi trypanothione reductase, putative 0.0148 0.0498 0.1724
Schistosoma mansoni nuclear receptor 0.0029 0.0027 0.0024
Loa Loa (eye worm) RNA binding protein 0.0252 0.0907 0.1211
Echinococcus multilocularis cathepsin L cysteine protease 0.0111 0.035 0.0347
Brugia malayi cathepsin F-like cysteine proteinase 0.0051 0.0113 0.0145
Onchocerca volvulus Alhambra homolog 0.0089 0.0263 0.0547
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0051 0.0113 0.011
Brugia malayi PHD-finger family protein 0.0024 0.0008 0.0003
Schistosoma mansoni hypothetical protein 0.0024 0.0008 0.0005
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0129 0.0423 0.042
Brugia malayi nuclear hormone receptor 0.0029 0.0027 0.0029
Toxoplasma gondii heat shock protein 90, putative 0.0097 0.0297 0.2129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Echinococcus multilocularis heat shock protein 90 0.0097 0.0297 0.0294
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0027 0.0029
Trypanosoma brucei heat shock protein 90, putative 0.0097 0.0297 0.3038
Loa Loa (eye worm) histone methyltransferase 0.0061 0.0155 0.0201
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0026 0.0017 0.0015
Loa Loa (eye worm) hypothetical protein 0.0053 0.0122 0.0157
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0027 0.0029
Brugia malayi Matrixin family protein 0.0036 0.0054 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0027 0.0029
Schistosoma mansoni cathepsin F (C01 family) 0.0111 0.035 0.0347
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0061 0.0154 0.0151
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0027 0.0024
Loa Loa (eye worm) PHD-finger family protein 0.0147 0.0493 0.0655
Trypanosoma cruzi transcription factor btf3, putative 0.0071 0.0192 0.065
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.005 0.0112 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Plasmodium falciparum serine repeat antigen 6 0.0051 0.0113 0.0776
Onchocerca volvulus 0.005 0.0111 0.0223
Echinococcus multilocularis neuropeptide s receptor 0.0466 0.1748 0.1746
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0051 0.0116 0.0798
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0152 0.0588
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0011 0.0037
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0051 0.0113 0.0145
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0027 0.0029
Echinococcus multilocularis Immunoglobulin 0.0029 0.0029 0.0026
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.0319 0.0316
Echinococcus multilocularis neuropeptide receptor A26 0.0466 0.1748 0.1746
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0157 0.0532 0.386
Plasmodium vivax serine-repeat antigen (SERA) 0.0051 0.0113 0.0776
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.2087 0.4431
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0203 0.0431
Schistosoma mansoni zinc finger protein 0.0024 0.0008 0.0005
Echinococcus granulosus SAM and MBT domain containing protein 0.0143 0.0477 0.0474
Brugia malayi nuclear receptor RXR 0.0032 0.0041 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0192 0.0408
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0798 0.3057 0.4099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0145 0.0307
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0907 0.0904
Loa Loa (eye worm) hypothetical protein 0.0176 0.0608 0.081
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0008 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0061 0.0154 0.02
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Loa Loa (eye worm) hypothetical protein 0.0152 0.0512 0.0681
Onchocerca volvulus Cathepsin L homolog 0.0111 0.035 0.0733
Trypanosoma brucei trypanothione reductase 0.0148 0.0498 0.5148
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Plasmodium falciparum glutathione reductase 0.0148 0.0498 0.3607
Brugia malayi photoreceptor-specific nuclear receptor 0.0061 0.0154 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0192 0.0408
Schistosoma mansoni hypothetical protein 0.2561 1 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0051 0.0116 0.0798
Loa Loa (eye worm) matrixin family protein 0.0086 0.0253 0.0332
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Schistosoma mansoni hypothetical protein 0.0024 0.0008 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0265 0.0959 0.0956
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Onchocerca volvulus 0.1218 0.4711 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0051 0.0116 0.0444
Brugia malayi PHD-finger family protein 0.0024 0.0008 0.0003
Plasmodium falciparum glutathione reductase 0.0051 0.0116 0.0798
Schistosoma mansoni atypical protein kinase C 0.01 0.0309 0.0306
Trypanosoma cruzi cysteine proteinase, putative 0.0103 0.0319 0.1095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0008 0.0003
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0069 0.0716
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0091 0.0273 0.1074
Loa Loa (eye worm) jmjC domain-containing protein 0.0131 0.043 0.0571
Brugia malayi hypothetical protein 0.0075 0.0211 0.0276
Brugia malayi jmjC domain containing protein 0.0029 0.0027 0.0028
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0091 0.0273 0.1074
Leishmania major cathepsin L-like protease 0.0111 0.035 0.3616
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Schistosoma mansoni inositol monophosphatase 0.0073 0.0203 0.02
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0092 0.0277 0.0365
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0043 0.0085 0.0106
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0142 0.0473 0.5247
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Brugia malayi PHD-finger family protein 0.0053 0.0122 0.0157
Brugia malayi Hypothetical C28H8.9 in chromosome III 0.0024 0.0008 0.0003
Leishmania major cathepsin L-like protease 0.0157 0.0532 0.552
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0059 0.0147 0.0313
Brugia malayi cathepsin L-like precursor 0.0059 0.0145 0.0187
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0111 0.035 0.0463
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Plasmodium vivax JmjC domain containing protein 0.0029 0.0027 0.0137
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0154 0.02
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0059 0.0147 0.1465
Schistosoma mansoni lamin 0.0026 0.0018 0.0015
Brugia malayi PHD-finger family protein 0.0089 0.0263 0.0346
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0061 0.0154 0.02
Entamoeba histolytica hypothetical protein 0.0035 0.0051 0.0512
Giardia lamblia Grp94/Hsp90 0.0091 0.0273 0.2294
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0061 0.0154 0.02
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.004 0.0071 0.0466
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.029 0.1057 0.1054
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0051 0.0116 0.1161
Echinococcus multilocularis geminin 0.1732 0.6737 0.6736
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Onchocerca volvulus 0.0051 0.0113 0.0229
Echinococcus granulosus fetal alzheimer antigen falz 0.0171 0.0587 0.0584
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Echinococcus granulosus muscleblind protein 0.0151 0.0508 0.0505
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0027 0.0024
Echinococcus multilocularis musashi 0.0026 0.0018 0.0015
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0026 0.0017 0.0014
Giardia lamblia NADH oxidase lateral transfer candidate 0.0051 0.0116 0.0527
Entamoeba histolytica cysteine proteinase, putative 0.0059 0.0145 0.1562
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0051 0.0113 0.0776
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0129 0.0423 0.042
Echinococcus multilocularis dnaJ subfamily B 0.2561 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Schistosoma mansoni heat shock protein 0.0097 0.0297 0.0294
Loa Loa (eye worm) hypothetical protein 0.0273 0.0991 0.1324
Plasmodium falciparum phd finger protein, putative 0.0089 0.0263 0.1879
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Trypanosoma brucei Heat shock protein 83, putative 0.0097 0.0297 0.3038
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0027 0.0024
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1071 0.413 0.5541
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.004 0.0073 0.0155
Brugia malayi cathepsin B-like cysteine proteinase 0.0745 0.2848 0.3819
Schistosoma mansoni tyrosine kinase 0.0034 0.0047 0.0044
Entamoeba histolytica cysteine proteinase 2 0.0103 0.0319 0.3517
Schistosoma mansoni hypothetical protein 0.1732 0.6737 0.6736
Echinococcus multilocularis lamin 0.0026 0.0018 0.0015
Echinococcus multilocularis cathepsin L cysteine protease 0.0111 0.035 0.0347
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0163 0.0557 0.0554
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Echinococcus granulosus histone lysine methyltransferase setb 0.0278 0.1011 0.1008
Loa Loa (eye worm) endoplasmin 0.0097 0.0297 0.0392
Loa Loa (eye worm) matrix metalloproteinase 0.0036 0.0054 0.0065
Brugia malayi Bromodomain containing protein 0.0277 0.1003 0.134
Loa Loa (eye worm) PHD-finger family protein 0.0089 0.0263 0.0346
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0474 0.0471
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0113 0.0495
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0439 0.1644 0.1642
Brugia malayi steroid hormone receptor 0.0061 0.0154 0.02
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0113 0.024
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0051 0.0116 0.0798
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0387 0.1438 0.1435
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0026 0.0017 0.0014
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0147 0.0491
Echinococcus granulosus remodeling and spacing factor 1 0.0024 0.0008 0.0005
Brugia malayi ecdysteroid receptor 0.0061 0.0154 0.02
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0027 0.0024
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0059 0.0147 0.0144
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0798 0.3057 0.4099
Brugia malayi Furin-like cysteine rich region family protein 0.1913 0.745 1
Schistosoma mansoni myst histone acetyltransferase 0.0024 0.0008 0.0005
Echinococcus multilocularis phd:f box containing protein 0.0029 0.0027 0.0023
Echinococcus multilocularis Protein lozenge 0.0055 0.0132 0.0129
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0473 0.047
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0083
Brugia malayi AF-10 protein 0.0029 0.0028 0.003
Brugia malayi chromobox protein homolog 3 0.0039 0.0067 0.0083
Loa Loa (eye worm) acetyltransferase 0.0163 0.0557 0.074
Echinococcus granulosus TAF3 RNA polymerase II TATA box binding protein 0.0024 0.0008 0.0005
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0032 0.0041 0.0048
Giardia lamblia Cathepsin B precursor 0.0265 0.0959 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0113 0.011
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0051 0.0116 0.0444
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0061 0.0154 0.0151
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Schistosoma mansoni hypothetical protein 0.0082 0.0235 0.0232
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0163 0.0557 0.0554
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Trichomonas vaginalis heat shock protein, putative 0.0057 0.0137 0.029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0103 0.0319 0.327
Echinococcus granulosus uro adherence factor A 0.0024 0.0008 0.0005
Brugia malayi Hemopexin family protein 0.005 0.0113 0.0144
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0152 0.0149
Echinococcus granulosus cathepsin b 0.0745 0.2848 0.2846
Onchocerca volvulus 0.0111 0.035 0.0733
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0061 0.0154 0.0316
Plasmodium falciparum endoplasmin, putative 0.0071 0.0192 0.1355
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0073 0.0203 0.5512
Brugia malayi acetyltransferase, GNAT family protein 0.0163 0.0557 0.074
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Echinococcus granulosus neuropeptide receptor A26 0.0466 0.1748 0.1746
Brugia malayi hypothetical protein 0.0441 0.1652 0.2212
Brugia malayi hypothetical protein 0.0049 0.0105 0.0134
Brugia malayi cathepsin Z-like cysteine proteinase 0.0051 0.0113 0.0145
Brugia malayi Hsp90 protein 0.0065 0.0168 0.0219
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0051 0.0116 0.0444
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0083 0.0242 0.0238
Brugia malayi Protein kinase domain containing protein 0.0817 0.3131 0.4199
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.035 0.3869
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0065 0.0168 0.0165
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Loa Loa (eye worm) fibroinase 0.0111 0.035 0.0463
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0027 0.0029
Trichomonas vaginalis inositol monophosphatase, putative 0.0073 0.0203 0.0431
Schistosoma mansoni hypothetical protein 0.0082 0.0235 0.0232
Onchocerca volvulus 0.0111 0.035 0.0733
Loa Loa (eye worm) hypothetical protein 0.0504 0.1899 0.2544
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0051 0.0116 0.0113
Plasmodium vivax SET domain containing protein 0.003 0.0032 0.0178
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0051 0.0113 0.0776
Brugia malayi Cathepsin L-like precursor 0.0059 0.0145 0.0187
Brugia malayi beta-NAC-like protein 0.0071 0.0192 0.0251
Onchocerca volvulus 0.0024 0.0008 0.0005
Echinococcus granulosus phd finger protein 12 0.0024 0.0008 0.0005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0203 0.0431
Plasmodium vivax vivapain-1 0.0103 0.0319 0.2291
Schistosoma mansoni endoplasmin 0.0097 0.0297 0.0294
Plasmodium falciparum serine repeat antigen 3 0.0051 0.0113 0.0776
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0051 0.0113 0.0776
Trypanosoma cruzi ISWI complex protein 0.0109 0.0343 0.1181
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0051 0.0113 0.024
Brugia malayi intermediate filament protein 0.0026 0.0018 0.0017
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0203 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0047
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0048
Schistosoma mansoni cpg binding protein 0.018 0.0622 0.0619
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0103 0.0319 0.327
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0211 0.1493
Plasmodium vivax heat shock protein 86, putative 0.0097 0.0297 0.2129
Loa Loa (eye worm) ctsf protein 0.0111 0.035 0.0463
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Loa Loa (eye worm) TK/EGFR protein kinase 0.1913 0.745 1
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0116 0.0381
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0163 0.0555 0.0552
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0111 0.035 0.0347
Brugia malayi Cathepsin L-like precursor 0.0059 0.0145 0.0187
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0027 0.0024
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2848 0.2846
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0011 0.0026
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0113 0.0495
Toxoplasma gondii Hsp90 domain-containing protein 0.0369 0.1365 1
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0011 0.0008
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0143 0.0477 0.0474
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0061 0.0154 0.0151
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0018 0.0017
Echinococcus multilocularis histone acetyltransferase MYST2 0.0163 0.0555 0.0552
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0027 0.0029
Leishmania major cathepsin L-like protease 0.0111 0.035 0.3616
Loa Loa (eye worm) CXXC zinc finger family protein 0.018 0.0622 0.0828
Leishmania major hypothetical protein, conserved 0.0075 0.0211 0.2151
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Leishmania major cathepsin L-like protease 0.0157 0.0532 0.552
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Echinococcus multilocularis tumor protein p63 0.0341 0.1257 0.1254
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1031 0.3974 0.3972
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0048
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0203 0.02
Trichomonas vaginalis endoplasmin, putative 0.0071 0.0192 0.0407
Schistosoma mansoni cpg binding protein 0.0204 0.0716 0.0713
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.0116 0.0381
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0319 0.3517
Trichomonas vaginalis heat shock protein, putative 0.0071 0.0192 0.0407
Trypanosoma brucei PAB1-binding protein , putative 0.0075 0.0211 0.213
Echinococcus granulosus zinc finger protein 0.0153 0.0518 0.0515
Onchocerca volvulus Protein ultraspiracle homolog 0.0061 0.0154 0.0316
Schistosoma mansoni cathepsin s 0.0052 0.012 0.0116
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0045 0.0095
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0027 0.0024
Loa Loa (eye worm) thioredoxin reductase 0.0148 0.0498 0.0661
Echinococcus granulosus heat shock protein 90 0.0083 0.0242 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0119 0.0252
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0278 0.1011 0.1008
Loa Loa (eye worm) hypothetical protein 0.0059 0.0145 0.0187
Trypanosoma brucei cysteine peptidase C (CPC) 0.0265 0.0959 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0113 0.024
Onchocerca volvulus 0.0111 0.035 0.0733
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0027 0.0024
Brugia malayi nuclear receptor NHR-67 0.0029 0.0027 0.0029
Echinococcus multilocularis thioredoxin glutathione reductase 0.0148 0.0498 0.0495
Plasmodium vivax unspecified product 0.0103 0.0319 0.2291
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0078 0.0167
Echinococcus multilocularis thyroid hormone receptor alpha 0.0061 0.0154 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.1161
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Brugia malayi mbt repeat family protein 0.0143 0.0477 0.0633
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0027 0.0024
Entamoeba histolytica hypothetical protein 0.0071 0.0192 0.2098
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0051 0.0113 0.0776
Loa Loa (eye worm) bromodomain containing protein 0.013 0.0424 0.0562
Brugia malayi Matrixin family protein 0.0036 0.0054 0.0065
Echinococcus granulosus tumor protein p63 0.0341 0.1257 0.1254
Mycobacterium tuberculosis Probable reductase 0.0338 0.1245 0.497
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0567 0.2146 0.2144
Brugia malayi Fibronectin type III domain containing protein 0.0029 0.0029 0.0032
Loa Loa (eye worm) hypothetical protein 0.0143 0.0477 0.0633
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Echinococcus multilocularis protein kinase c iota type 0.0094 0.0286 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0154 0.02
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0073 0.0203 0.2214
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Schistosoma mansoni intermediate filament proteins 0.0026 0.0018 0.0015
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0032 0.0041 0.0038
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0038
Trichomonas vaginalis helicase, putative 0.0041 0.0074 0.0158
Trypanosoma cruzi cysteine peptidase, putative 0.0157 0.0532 0.1845
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0168 0.0577 0.0574
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0473 0.047
Schistosoma mansoni microtubule-associated protein tau 0.1364 0.5286 0.5284
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0051 0.0113 0.121
Onchocerca volvulus 0.0461 0.1731 0.3666
Loa Loa (eye worm) matrixin family protein 0.0079 0.0225 0.0295
Toxoplasma gondii cathepsin B 0.0265 0.0959 0.7007
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Echinococcus multilocularis phd finger protein 12 0.0024 0.0008 0.0005
Loa Loa (eye worm) DR-78 0.0029 0.0027 0.0029
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0061 0.0154 0.0151
Onchocerca volvulus Tyrosine kinase homolog 0.0458 0.1717 0.3638
Onchocerca volvulus Bile acid receptor homolog 0.0061 0.0154 0.0316
Schistosoma mansoni cpg binding protein 0.0204 0.0716 0.0713
Toxoplasma gondii heat shock protein HSP90 0.0097 0.0297 0.2129
Echinococcus multilocularis lysine specific demethylase 5B 0.0024 0.0008 0.0005
Entamoeba histolytica transcription factor BTF3, putative 0.0071 0.0192 0.2098
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0041 0.0048
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0027 0.0024
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0073 0.0203 0.0791
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0142 0.0473 0.0628
Plasmodium falciparum serine repeat antigen 5 0.0051 0.0113 0.0776
Giardia lamblia Cysteine protease 0.0051 0.0113 0.0495
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0061 0.0154 0.0151
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0078 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0154 0.02
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0027 0.0046
Echinococcus granulosus ecdysone induced protein 78C 0.0061 0.0154 0.0151
Brugia malayi Thioredoxin reductase 0.0148 0.0498 0.0661
Schistosoma mansoni chromobox protein 0.0069 0.0187 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0147 0.0313
Echinococcus granulosus FTZ F1 alpha 0.0061 0.0154 0.0151
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0029 0.0028 0.0148
Leishmania major cathepsin L-like protease 0.0111 0.035 0.3616
Trypanosoma brucei heat shock protein 84, putative 0.0065 0.0168 0.1687
Schistosoma mansoni cathepsin F (C01 family) 0.0111 0.035 0.0347
Loa Loa (eye worm) hypothetical protein 0.0294 0.1072 0.1432
Echinococcus multilocularis cathepsin b 0.0745 0.2848 0.2846
Schistosoma mansoni SET domain protein 0.0033 0.0046 0.0042
Schistosoma mansoni zinc finger protein 0.0109 0.0343 0.034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0473 0.047
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Trichomonas vaginalis bromodomain-containing protein, putative 0.006 0.015 0.0318
Onchocerca volvulus 0.0059 0.0145 0.0296
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0082
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0024 0.0009 0.0006
Echinococcus granulosus cathepsin L 0.0103 0.0319 0.0316
Plasmodium falciparum cysteine proteinase falcipain 1 0.0103 0.0319 0.2291
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0147 0.0494 0.0491
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0061 0.0154 0.0151
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0113 0.024
Schistosoma mansoni bromodomain containing protein 0.0044 0.0088 0.0085
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Leishmania major cathepsin L-like protease 0.0157 0.0532 0.552
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Schistosoma mansoni methyl-cpg binding protein mbd 0.0122 0.0393 0.039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Trichomonas vaginalis heat shock protein, putative 0.0097 0.0297 0.063
Echinococcus multilocularis lamin dm0 0.0026 0.0018 0.0015
Toxoplasma gondii PHD-finger domain-containing protein 0.0089 0.0263 0.1879
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0035 0.0053 0.0049
Brugia malayi PHD-finger family protein 0.0024 0.0008 0.0003
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0615 0.2338 0.2336
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0256 0.0923 0.092
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Schistosoma mansoni lozenge 0.0055 0.0132 0.0129
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0051 0.0113 0.011
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.1161
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0061 0.0154 0.02
Leishmania major hypothetical protein, conserved 0.0029 0.0027 0.0222
Toxoplasma gondii cathepsin CPC2 0.0051 0.0113 0.0776
Onchocerca volvulus 0.0026 0.0018 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0154 0.02
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0142 0.0473 0.5247
Brugia malayi SET domain containing protein 0.0033 0.0046 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Trichomonas vaginalis heat shock protein, putative 0.0091 0.0273 0.058
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0091 0.0273 1
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0026 0.0017 0.0036
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0008 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Loa Loa (eye worm) hypothetical protein 0.0089 0.0263 0.0346
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0153
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Echinococcus granulosus heat shock protein 0.0097 0.0297 0.0294
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0017 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0061 0.0154 0.02
Echinococcus granulosus PHD and RING finger domain containing protein 1 0.0024 0.0008 0.0005
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0111 0.035 0.2522
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0065 0.0168 0.1828
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0265 0.0959 0.3349
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0028 0.0211
Plasmodium falciparum cysteine proteinase falcipain 3 0.0111 0.035 0.2522
Schistosoma mansoni phosphatidylserine receptor 0.0029 0.0027 0.0023
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0029 0.0027 0.0023
Brugia malayi latrophilin 2 splice variant baaae 0.0176 0.0608 0.081
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0122 0.0393 0.039
Schistosoma mansoni cathepsin S (C01 family) 0.0051 0.0113 0.011
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0028 0.0211
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0048
Loa Loa (eye worm) steroid hormone receptor 0.0061 0.0154 0.02
Schistosoma mansoni cell adhesion molecule 0.0039 0.0067 0.0063
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0187 0.0244
Brugia malayi jmjC domain containing protein 0.0029 0.0027 0.0028
Plasmodium falciparum serine repeat antigen 9 0.0051 0.0113 0.0776
Loa Loa (eye worm) F/Y-rich family protein 0.0024 0.0008 0.0003
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0061 0.0154 0.0151
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Entamoeba histolytica heat shock protein 90, putative 0.0097 0.0297 0.327
Entamoeba histolytica hypothetical protein 0.0073 0.0203 0.2213
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0024 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Loa Loa (eye worm) latrophilin receptor protein 2 0.0082 0.0235 0.0309
Loa Loa (eye worm) TK/FAK protein kinase 0.0817 0.3131 0.4199
Echinococcus granulosus geminin 0.1732 0.6737 0.6736
Brugia malayi nuclear receptor RXR 0.0029 0.0027 0.0029
Treponema pallidum fructose-bisphosphate aldolase 0.0142 0.0473 1
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.0119 0.0253
Leishmania major cysteine peptidase A (CPA) 0.0111 0.035 0.3616
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0051 0.0113 0.0776
Giardia lamblia Cathepsin L-like protease 0.0051 0.0113 0.0495
Echinococcus multilocularis jumonji domain containing 1A 0.0029 0.0027 0.0023
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0051 0.0113 0.011
Brugia malayi jmjC domain containing protein 0.029 0.1057 0.1412
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0154 0.0151
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Brugia malayi F/Y-rich N-terminus family protein 0.0103 0.032 0.0423
Loa Loa (eye worm) ICD-1 protein 0.0071 0.0192 0.0251
Trypanosoma cruzi cysteine proteinase, putative 0.0103 0.0319 0.1095
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0051 0.0113 0.0776
Echinococcus granulosus methyl CpG binding domain protein 2 0.0122 0.0393 0.039
Brugia malayi Calcitonin receptor-like protein seb-1 0.0258 0.0929 0.1241
Brugia malayi Heterochromatin protein 1 0.0069 0.0187 0.0244
Schistosoma mansoni vesicular amine transporter 0.0029 0.0029 0.0026
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0027 0.0024
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0657 0.25 1
Plasmodium vivax ataxin-2 like protein, putative 0.0075 0.0211 0.1493
Brugia malayi ecdysone receptor 0.0029 0.0027 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0907 0.0904
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Loa Loa (eye worm) hypothetical protein 0.0046 0.0096 0.0122
Trypanosoma cruzi heat shock protein 85, putative 0.0097 0.0297 0.1017
Trypanosoma cruzi cysteine protease, putative 0.0103 0.0319 0.1095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0047 0.0044
Toxoplasma gondii histone lysine methyltransferase SET1 0.0367 0.1358 0.9948
Schistosoma mansoni bromodomain containing protein 0.0465 0.1745 0.1742
Echinococcus multilocularis GPCR, family 2 0.0082 0.0235 0.0232
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0079 0.0226 0.0223
Onchocerca volvulus 0.0111 0.035 0.0733
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0051 0.0113 0.0776
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.2087 0.4431
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0489 0.1841 0.2465
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0052 0.0121 0.0117
Loa Loa (eye worm) hypothetical protein 0.0745 0.2848 0.3819
Echinococcus multilocularis SAM and MBT domain containing protein 0.0143 0.0477 0.0474
Toxoplasma gondii heat shock protein 75, putative 0.0065 0.0168 0.1182
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0187 0.0397
Schistosoma mansoni nuclear hormone receptor 0.0061 0.0154 0.0151
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Echinococcus granulosus twitchin 0.0037 0.0059 0.0056
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0258 0.0929 0.1241
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0907 0.0904
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0041 0.0038
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0113 0.0371
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0026 0.0017 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0152 0.0588
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.006 0.015 0.0318
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0211 0.0713
Echinococcus granulosus phd finger protein 10 0.0024 0.0008 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus multilocularis insulin receptor 0.0615 0.2338 0.2336
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0067 0.0142
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0113 0.011
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0338 0.1245 0.497
Loa Loa (eye worm) heat shock protein 90 0.0097 0.0297 0.0392
Echinococcus multilocularis PHD finger protein rhinoceros 0.0089 0.0263 0.026
Schistosoma mansoni nuclear receptor 0.0029 0.0027 0.0024
Echinococcus multilocularis cathepsin L 0.0103 0.0319 0.0316
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0278 0.1011 0.1008
Echinococcus multilocularis cysteine protease 0.0111 0.035 0.0347
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0745 0.2848 0.2846
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0152 0.0149
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.029 0.1057 0.1054
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.035 0.0463
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0061 0.0154 0.02
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0027 0.0028
Onchocerca volvulus 0.0024 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Trypanosoma cruzi cysteine peptidase, putative 0.0157 0.0532 0.1845
Giardia lamblia Cathepsin B precursor 0.0051 0.0113 0.0495
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Loa Loa (eye worm) runx1 0.0055 0.0132 0.017
Plasmodium falciparum heat shock protein 90, putative 0.0057 0.0137 0.0948
Trypanosoma cruzi transcription factor btf3, putative 0.0071 0.0192 0.065
Schistosoma mansoni myst-related protein 0.0035 0.0051 0.0048
Plasmodium falciparum heat shock protein 90, putative 0.0369 0.1365 1
Echinococcus multilocularis polycomb protein SCMH1 0.0143 0.0477 0.0474
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0153
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0027 0.0066
Schistosoma mansoni tyrosine kinase 0.0615 0.2338 0.2336
Brugia malayi protein kinase C3,putative 0.0086 0.0254 0.0334
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Echinococcus granulosus jumonji domain containing protein 0.0123 0.04 0.0397
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0157 0.0532 0.0529
Onchocerca volvulus Glucosylceramidase homolog 0.0524 0.1976 0.4188
Loa Loa (eye worm) hypothetical protein 0.0111 0.035 0.0463
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.005 0.0112 0.0109
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0211 0.1493
Plasmodium vivax histone acetyltransferase GCN5, putative 0.006 0.015 0.1045
Giardia lamblia Heat shock protein HSP 90-alpha 0.0097 0.0297 0.2558
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Echinococcus multilocularis roundabout 2 0.0046 0.0096 0.0093
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Giardia lamblia Hypothetical protein 0.0051 0.0113 0.0495
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0027 0.0024
Echinococcus multilocularis FTZ F1 alpha 0.0061 0.0154 0.0151
Schistosoma mansoni phd finger protein 0.0024 0.0008 0.0005
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Echinococcus multilocularis heat shock protein 90 0.0083 0.0242 0.0238
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0067 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.004 0.0073 0.0229
Onchocerca volvulus 0.0061 0.0154 0.0316
Schistosoma mansoni hypothetical protein 0.005 0.0113 0.0109
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0171 0.0587 0.0584
Onchocerca volvulus 0.0029 0.0027 0.0046
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0152 0.0588
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0173 0.067
Schistosoma mansoni hypothetical protein 0.0872 0.335 0.3348
Echinococcus granulosus Zinc finger DBF type 0.0024 0.0008 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0319 0.3517
Onchocerca volvulus 0.0111 0.035 0.0733
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Loa Loa (eye worm) mbt repeat family protein 0.0143 0.0477 0.0633
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0113 0.0145
Mycobacterium tuberculosis Probable oxidoreductase 0.0376 0.1394 0.5565
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0657 0.25 1
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.025 0.0897 1
Brugia malayi cathepsin L precursor 0.0051 0.0113 0.0145
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Plasmodium vivax SET domain protein, putative 0.0157 0.0532 0.386
Echinococcus multilocularis jumonji domain containing protein 0.0123 0.04 0.0397
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0439 0.1644 0.1642
Onchocerca volvulus 0.0024 0.0008 0.0005
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0038 0.0062 0.0077
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0473 0.047
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0029 0.0029 0.0026
Loa Loa (eye worm) hypothetical protein 0.0163 0.0555 0.0738
Loa Loa (eye worm) inositol-1 0.0073 0.0203 0.0265
Echinococcus granulosus lysine specific demethylase 6a 0.0029 0.0027 0.0023
Echinococcus multilocularis endoplasmin 0.0091 0.0273 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0047
Loa Loa (eye worm) hypothetical protein 0.0059 0.0145 0.0187
Brugia malayi Papain family cysteine protease containing protein 0.0103 0.0319 0.0421
Brugia malayi Matrixin family protein 0.0086 0.0253 0.0332
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Entamoeba histolytica heat shock protein 90, putative 0.0097 0.0297 0.327
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0051 0.0113 0.0776
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0027 0.0024
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0061 0.0154 0.0151
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Plasmodium vivax vivapain-2 0.0111 0.035 0.2522
Schistosoma mansoni tyrosine kinase 0.0615 0.2338 0.2336
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0338 0.1245 0.497
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0187 0.0397
Echinococcus granulosus thioredoxin glutathione reductase 0.0148 0.0498 0.0495
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0154 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Plasmodium falciparum serine repeat antigen 8 0.0051 0.0113 0.0776
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0203 0.0686
Plasmodium vivax unspecified product 0.0052 0.012 0.0823
Echinococcus multilocularis 0.059 0.2239 0.2237
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0203 0.0686
Plasmodium vivax thioredoxin reductase, putative 0.0148 0.0498 0.3607
Schistosoma mansoni coup transcription factor 0.0061 0.0154 0.0151
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0256 0.0923 0.092
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0082 0.0235 0.0309
Onchocerca volvulus 0.0111 0.035 0.0733
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0113 0.0145
Brugia malayi Cathepsin L-like cysteine proteinase 0.0059 0.0145 0.0187
Plasmodium vivax unspecified product 0.0051 0.0113 0.0776
Trypanosoma cruzi heat shock protein 85, putative 0.0097 0.0297 0.1017
Echinococcus granulosus protein tyrosine kinase 0.0808 0.3094 0.3092
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0265 0.0959 0.2036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Loa Loa (eye worm) hypothetical protein 0.0151 0.0508 0.0675
Schistosoma mansoni lamin 0.0026 0.0018 0.0015
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Loa Loa (eye worm) hypothetical protein 0.0151 0.0508 0.0675
Echinococcus granulosus transcription factor btf3 0.0071 0.0192 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Trypanosoma cruzi heat shock protein 90, putative 0.0097 0.0297 0.1017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0082 0.0235 0.0232
Echinococcus multilocularis cpg binding protein 0.0204 0.0716 0.0713
Echinococcus granulosus neuroglian 0.0037 0.0058 0.0055
Onchocerca volvulus 0.0143 0.0477 0.1001
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0657 0.25 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Plasmodium falciparum JmjC domain-containing protein, putative 0.0029 0.0027 0.0137
Echinococcus granulosus chromobox protein 1 0.0069 0.0187 0.0184
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0061 0.0155 0.0152
Loa Loa (eye worm) hypothetical protein 0.0075 0.0211 0.0276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Loa Loa (eye worm) MH2 domain-containing protein 0.0241 0.0862 0.115
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0111 0.035 0.2522
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0053 0.0049
Schistosoma mansoni tyrosine kinase 0.1014 0.3908 0.3906
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0142 0.0473 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0192 0.0408
Echinococcus multilocularis cathepsin b 0.0745 0.2848 0.2846
Trypanosoma cruzi cysteine peptidase, putative 0.0103 0.0319 0.1095
Plasmodium vivax vivapain-3 0.0103 0.0319 0.2291
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0061 0.0154 0.02
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Trichomonas vaginalis glutathione reductase, putative 0.0051 0.0116 0.0247
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0103 0.0319 0.0677
Brugia malayi hypothetical protein 0.0024 0.0008 0.0003
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0051 0.0113 0.0776
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0145 0.0307
Echinococcus granulosus chromobox protein 1 0.0069 0.0187 0.0184
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Brugia malayi heat shock protein 90 0.0097 0.0297 0.0392
Loa Loa (eye worm) hypothetical protein 0.0318 0.1166 0.1558
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Loa Loa (eye worm) hypothetical protein 0.0043 0.0085 0.0106
Trypanosoma cruzi major cysteine proteinase, putative 0.0097 0.0295 0.101
Echinococcus multilocularis protein tyrosine kinase 0.0808 0.3094 0.3092
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Echinococcus granulosus lysine specific demethylase 5A 0.0131 0.043 0.0427
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0061 0.0154 0.02
Giardia lamblia Cathepsin B precursor 0.0051 0.0113 0.0495
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0152 0.1539
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0051 0.0113 0.0776
Schistosoma mansoni hypothetical protein 0.0034 0.0047 0.0044
Trypanosoma cruzi heat shock protein 90, putative 0.0041 0.0074 0.0234
Schistosoma mansoni tyrosine kinase 0.1031 0.3974 0.3972
Schistosoma mansoni zinc finger protein 0.0029 0.0027 0.0024
Schistosoma mansoni endoplasmin 0.0097 0.0297 0.0294
Onchocerca volvulus 0.018 0.0622 0.1311
Schistosoma mansoni phd finger protein 0.0024 0.0008 0.0005
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0154 0.02
Brugia malayi hypothetical protein 0.0073 0.0203 0.0265
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Echinococcus granulosus protein kinase c iota type 0.0094 0.0286 0.0283
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0113 0.011
Onchocerca volvulus 0.0168 0.0577 0.1214
Brugia malayi jmjC domain containing protein 0.0131 0.043 0.0571
Echinococcus granulosus peregrin 0.0109 0.0343 0.034
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0051 0.0116 0.0113
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0027 0.0024
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0059 0.0147 0.0144
Schistosoma mansoni heat shock protein 0.0065 0.0168 0.0165
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Brugia malayi mbt repeat family protein 0.0143 0.0477 0.0633
Echinococcus granulosus lamin dm0 0.0026 0.0018 0.0015
Brugia malayi Cathepsin L-like precursor 0.0052 0.012 0.0153
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0173 0.067
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0061 0.0155 0.0152
Schistosoma mansoni heat shock protein 0.0097 0.0297 0.0294
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0069 0.0452
Echinococcus granulosus intermediate filament protein 0.0026 0.0018 0.0015
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0051 0.0113 0.011
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0027 0.0029
Schistosoma mansoni transcription factor btf3 0.0071 0.0192 0.0189
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0032 0.0041 0.0038
Mycobacterium ulcerans heat shock protein 90 0.0091 0.0273 0.1074
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0045 0.0095
Brugia malayi hypothetical protein 0.0029 0.0029 0.0032
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0061 0.0154 0.0151
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0073 0.0203 0.1436
Schistosoma mansoni protein phosphatase 2C 0.0029 0.0027 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Trypanosoma brucei ISWI complex protein 0.0109 0.0343 0.3527
Echinococcus granulosus mixed lineage leukemia protein mll 0.005 0.0112 0.0109
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0082 0.0235 0.0232
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0203 0.207
Schistosoma mansoni jumonji/arid domain-containing protein 0.0131 0.043 0.0427
Schistosoma mansoni hypothetical protein 0.0147 0.0493 0.049
Schistosoma mansoni fyve-containing 0.0024 0.0008 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0113 0.024
Leishmania major heat shock protein, putative 0.0065 0.0168 0.1708
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0157 0.0532 0.0529
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0745 0.2848 1
Loa Loa (eye worm) glutathione reductase 0.0148 0.0498 0.0661
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0011 0.0024
Leishmania major cathepsin L-like protease 0.0111 0.035 0.3616
Brugia malayi Papain family cysteine protease containing protein 0.0103 0.0319 0.0421
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0082 0.0235 0.0232
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0059 0.0147 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0119 0.0252
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0082 0.0235 0.0232
Brugia malayi jmjC domain containing protein 0.0029 0.0027 0.0028
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0085 0.0247 0.0244
Mycobacterium leprae PROBABLE HYDROLASE 0.0043 0.0085 0.0317
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Brugia malayi RNA recognition motif domain containing protein 0.0252 0.0907 0.1211
Echinococcus multilocularis peregrin 0.0109 0.0343 0.034
Echinococcus granulosus defective proboscis extension response 0.0029 0.0029 0.0026
Plasmodium falciparum serine repeat antigen 7 0.0051 0.0113 0.0776
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Echinococcus granulosus histone acetyltransferase myst3 0.0024 0.0008 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0147 0.0491
Giardia lamblia Cysteine protease 0.0051 0.0113 0.0495
Schistosoma mansoni myelin transcription factor 1 myt1 0.0163 0.0555 0.0552
Plasmodium falciparum serine repeat antigen 4 0.0051 0.0113 0.0776
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0338 0.1245 0.497
Onchocerca volvulus 0.005 0.0113 0.0228
Echinococcus granulosus heat shock protein 90 0.0097 0.0297 0.0294
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0029 0.0027 0.0196
Echinococcus granulosus lysine specific demethylase 5B 0.0024 0.0008 0.0005
Schistosoma mansoni cathepsin F (C01 family) 0.0059 0.0145 0.0141
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0005
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0252 0.0907 0.1211
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0203 0.02
Schistosoma mansoni cathepsin B (C01 family) 0.0051 0.0113 0.011
Brugia malayi Protein kinase domain containing protein 0.0615 0.2338 0.3133
Trypanosoma cruzi heat shock protein 85, putative 0.0083 0.0242 0.0823
Echinococcus multilocularis chromobox protein 1 0.0069 0.0187 0.0184
Trypanosoma cruzi heat shock protein 90, putative 0.0083 0.0242 0.0823
Brugia malayi CXXC zinc finger family protein 0.018 0.0622 0.0828
Schistosoma mansoni jumonji domain containing protein 0.0231 0.0822 0.0819
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0067 0.0142
Giardia lamblia Cathepsin B precursor 0.0051 0.0113 0.0495
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0113 0.011
Onchocerca volvulus 0.0026 0.0018 0.0027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Echinococcus granulosus JmjC domain containing protein 4 0.0029 0.0027 0.0023
Echinococcus multilocularis transcription factor btf3 0.0071 0.0192 0.0189
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Echinococcus granulosus epidermal growth factor receptor 0.1913 0.745 0.7449
Echinococcus granulosus Immunoglobulin 0.0029 0.0029 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0061 0.0154 0.02
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0043 0.0085 0.0317
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0338 0.1245 0.497
Schistosoma mansoni inositol monophosphatase 0.0073 0.0203 0.02
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0112
Echinococcus multilocularis PHD finger protein 14 0.0024 0.0008 0.0005
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0061 0.0154 0.02
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0061 0.0154 0.0151
Loa Loa (eye worm) hypothetical protein 0.0278 0.1011 0.135
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0061 0.0154 0.0151
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0113 0.011
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0051 0.0116 0.1138
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0148 0.0498 0.1973
Plasmodium vivax hypothetical protein, conserved 0.0089 0.0263 0.1879
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0051 0.0113 0.0495
Trypanosoma cruzi heat shock protein, putative 0.0065 0.0168 0.0565
Schistosoma mansoni hepatitis B virus X associated protein hbxa 0.0024 0.0008 0.0005
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0033 0.0044 0.0153
Echinococcus granulosus cathepsin l1 0.0059 0.0145 0.0141
Schistosoma mansoni jumonji/arid domain-containing protein 0.0131 0.043 0.0427
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0065
Loa Loa (eye worm) hypothetical protein 0.0046 0.0096 0.0122
Trypanosoma cruzi cruzipain precursor, putative 0.0052 0.012 0.0393
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0113 0.0229
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Schistosoma mansoni chromobox protein 0.0069 0.0187 0.0184
Plasmodium falciparum thioredoxin reductase 0.0148 0.0498 0.3607
Echinococcus granulosus cpg binding protein 0.0204 0.0716 0.0713
Echinococcus granulosus cathepsin l1 0.0111 0.035 0.0347
Schistosoma mansoni sex comb on midleg homolog 0.0143 0.0477 0.0474
Giardia lamblia Cysteine protease 0.0051 0.0113 0.0495
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0048
Onchocerca volvulus 0.003 0.0034 0.006
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Entamoeba histolytica cysteine proteinase 1, putative 0.0103 0.0319 0.3517
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0033 0.0044 0.0153
Brugia malayi CHD4 protein 0.0035 0.0053 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Leishmania major basic transcription factor 3a, putative 0.0071 0.0192 0.1961
Plasmodium falciparum basic transcription factor 3b, putative 0.0071 0.0192 0.1359
Echinococcus multilocularis cysteine protease 0.0111 0.035 0.0347
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.0116 0.1138
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0017
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0154 0.0151
Schistosoma mansoni hypothetical protein 0.0089 0.0263 0.026
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0147 0.0491
Toxoplasma gondii cathepsin CPC1 0.0051 0.0113 0.0776
Brugia malayi cathepsin Z-like cysteine proteinase 0.0051 0.0113 0.0145
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0111 0.035 0.0463
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0061 0.0154 0.0151
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0203 0.2049
Echinococcus granulosus phd:f box containing protein 0.0029 0.0027 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0119 0.0252
Giardia lamblia Cathepsin B precursor 0.0051 0.0113 0.0495
Schistosoma mansoni steroid hormone receptor ad4bp 0.0061 0.0154 0.0151
Schistosoma mansoni tyrosine kinase 0.1014 0.3908 0.3906
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0051 0.0116 0.1161
Echinococcus granulosus tar DNA binding protein 0.0252 0.0907 0.0904
Schistosoma mansoni hypothetical protein 0.0024 0.0008 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0061 0.0154 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Echinococcus multilocularis microtubule associated protein 2 0.1364 0.5286 0.5284
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0907 0.0904
Brugia malayi fibroinase precursor 0.0051 0.0113 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.2 nM In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII ChEMBL. 8064808
IC50 (binding) = 1.2 nM In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII ChEMBL. 8064808
IC50 (binding) = 720 nM In vitro inhibitory activity against angiotensin II rat midbrain AT2 receptor using radioligand [125I]-Sar Ile-AII ChEMBL. 8064808
IC50 (binding) = 720 nM In vitro inhibitory activity against angiotensin II rat midbrain AT2 receptor using radioligand [125I]-Sar Ile-AII ChEMBL. 8064808

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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