Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0024 | 0.0397 | 0.5 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0024 | 0.0397 | 0.5 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0178 | 0.7362 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0024 | 0.0397 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0087 | 0.3254 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0087 | 0.3254 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0024 | 0.0397 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0024 | 0.0397 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0024 | 0.0397 | 0.1221 |
Toxoplasma gondii | cathepsin CPL | 0.0024 | 0.0397 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0024 | 0.0397 | 0.0397 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0024 | 0.0397 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0024 | 0.0397 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0024 | 0.0397 | 0.1221 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0024 | 0.0397 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0024 | 0.0397 | 0.1221 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0024 | 0.0397 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0024 | 0.0397 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.3254 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0087 | 0.3254 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0191 | 0.7974 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Plasmodium vivax | unspecified product | 0.022 | 0.9288 | 0.9288 |
Plasmodium vivax | vivapain-3 | 0.0024 | 0.0397 | 0.0397 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0024 | 0.0397 | 0.1221 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0024 | 0.0397 | 0.1221 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0087 | 0.3254 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0024 | 0.0397 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0024 | 0.0397 | 0.5 |
Onchocerca volvulus | 0.0024 | 0.0397 | 0.5 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0024 | 0.0397 | 0.1221 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0024 | 0.0397 | 0.0397 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0024 | 0.0397 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0024 | 0.0397 | 0.1221 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0087 | 0.3254 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0024 | 0.0397 | 0.1221 |
Plasmodium vivax | vivapain-1 | 0.0236 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0024 | 0.0397 | 0.1221 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0024 | 0.0397 | 0.1221 |
Onchocerca volvulus | 0.0024 | 0.0397 | 0.5 | |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Onchocerca volvulus | 0.0024 | 0.0397 | 0.5 | |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0024 | 0.0397 | 0.1221 |
Plasmodium vivax | unspecified product | 0.0236 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.3254 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Onchocerca volvulus | Cathepsin F homolog | 0.0024 | 0.0397 | 0.5 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0024 | 0.0397 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0087 | 0.3254 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0087 | 0.3254 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Onchocerca volvulus | 0.0024 | 0.0397 | 0.5 | |
Loa Loa (eye worm) | ctsf protein | 0.0024 | 0.0397 | 0.1221 |
Entamoeba histolytica | cysteine protease, putative | 0.0024 | 0.0397 | 0.5 |
Onchocerca volvulus | 0.0024 | 0.0397 | 0.5 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0087 | 0.3254 | 1 |
Leishmania major | cathepsin L-like protease | 0.0024 | 0.0397 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0087 | 0.3254 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0024 | 0.0397 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0024 | 0.0397 | 0.1221 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0024 | 0.0397 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Leishmania major | cysteine peptidase A (CPA) | 0.0024 | 0.0397 | 0.5 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0191 | 0.7974 | 0.5 |
Loa Loa (eye worm) | fibroinase | 0.0024 | 0.0397 | 0.1221 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0087 | 0.3254 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0397 | 0.1221 |
Leishmania major | cathepsin L-like protease | 0.0024 | 0.0397 | 0.5 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0024 | 0.0397 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Onchocerca volvulus | 0.0024 | 0.0397 | 0.5 | |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0024 | 0.0397 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0024 | 0.0397 | 0.1221 |
Loa Loa (eye worm) | carboxylesterase | 0.0087 | 0.3254 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0024 | 0.0397 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0024 | 0.0397 | 0.5 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0024 | 0.0397 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0024 | 0.0397 | 0.1221 |
Brugia malayi | Cathepsin L-like precursor | 0.0024 | 0.0397 | 0.1221 |
Loa Loa (eye worm) | cysteine protease | 0.0024 | 0.0397 | 0.1221 |
Onchocerca volvulus | Cathepsin L homolog | 0.0024 | 0.0397 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0024 | 0.0397 | 1 |
Leishmania major | cathepsin L-like protease | 0.0024 | 0.0397 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0024 | 0.0397 | 0.5 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0024 | 0.0397 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0024 | 0.0397 | 0.1221 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0024 | 0.0397 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.