TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 385.586 | Formula: C24H39N3O
H donors: 1 H acceptors: 1 LogP: 7.15 Rotable bonds: 14
Rule of 5 violations (Lipinski): 1
SMILES: CCCCCCCCCCCCc1ccc(cc1)C(=O)N1CCC[C@@H]1C(=N)N
InChi: 1S/C24H39N3O/c1-2-3-4-5-6-7-8-9-10-11-13-20-15-17-21(18-16-20)24(28)27-19-12-14-22(27)23(25)26/h15-18,22H,2-14,19H2,1H3,(H3,25,26)/t22-/m1/s1
InChiKey: DHYWGRWKWDDFMU-JOCHJYFZSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0175	0.0175
Schistosoma mansoni	nuclear receptor nhr-48	0.011	0.1305	0.1305
Schistosoma mansoni	calpain C (C02 family)	0.0066	0.0534	0.0534
Brugia malayi	Papain family cysteine protease containing protein	0.0172	0.2415	0.2415
Plasmodium vivax	serine-repeat antigen (SERA)	0.0046	0.0166	0.0686
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.011	0.1305	0.1305
Trypanosoma cruzi	cruzipain precursor, putative	0.0051	0.0264	0.0264
Leishmania major	calpain, putative,cysteine peptidase, Clan CA, family C2, putative	0.0066	0.0534	0.1666
Loa Loa (eye worm)	bone morphogenetic protein 1b	0.0045	0.0148	0.0148
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.011	0.1305	0.3738
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.011	0.1305	0.1305
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0046	0.0166	0.0166
Brugia malayi	cathepsin F-like cysteine proteinase	0.0051	0.0264	0.0264
Plasmodium vivax	serine-repeat antigen 4 (SERA), putative	0.0046	0.0166	0.0686
Onchocerca volvulus		0.0172	0.2415	0.6915
Loa Loa (eye worm)	hypothetical protein	0.0176	0.2486	0.2486
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0046	0.0166	0.0686
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0232	0.3492	0.3492
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0232	0.3492	0.3492
Onchocerca volvulus	Cathepsin L homolog	0.0172	0.2415	0.6915
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0232	0.3492	0.3492
Entamoeba histolytica	cysteine proteinase, putative	0.0097	0.1078	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0232	0.3492	0.3492
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0046	0.0166	0.0516
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0232	0.3492	0.3492
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0036	0	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Plasmodium vivax	serine-repeat antigen 3 (SERA)	0.0046	0.0166	0.0686
Echinococcus granulosus	cysteine protease	0.0097	0.1078	0.1078
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0066	0.0534	0.0534
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0232	0.3492	0.3492
Echinococcus multilocularis	cysteine protease	0.0172	0.2415	0.2415
Brugia malayi	nuclear hormone receptor	0.0232	0.3492	0.3492
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Schistosoma mansoni	gamma-secretase subunit aph-1	0.0237	0.3576	0.3576
Entamoeba histolytica	cysteine proteinase, putative	0.0172	0.2415	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0232	0.3492	0.3492
Schistosoma mansoni	nuclear receptor	0.011	0.1305	0.1305
Entamoeba histolytica	cysteine proteinase, putative	0.0172	0.2415	1
Plasmodium vivax	unspecified product	0.0051	0.0264	0.1095
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0232	0.3492	0.3492
Leishmania major	cathepsin L-like protease	0.0172	0.2415	0.753
Brugia malayi	cathepsin F-like cysteine proteinase	0.0046	0.0166	0.0166
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0121	0.1503	0.1503
Brugia malayi	Cathepsin L-like precursor	0.0172	0.2415	0.2415
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0598	1	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0051	0.0264	0.0264
Loa Loa (eye worm)	hypothetical protein	0.0232	0.3492	0.3492
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0172	0.2415	0.753
Trichomonas vaginalis	Clan CA, family C1, cathepsin H-like cysteine peptidase	0.0046	0.0166	0.0516
Entamoeba histolytica	cysteine proteinase 1, putative	0.0097	0.1078	0.4054
Onchocerca volvulus		0.0172	0.2415	0.6915
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0046	0.0166	0.0166
Echinococcus granulosus	cathepsin L	0.0097	0.1078	0.1078
Brugia malayi	nuclear receptor NHR-88	0.0232	0.3492	0.3492
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0046	0.0166	0.0516
Onchocerca volvulus		0.0046	0.0166	0.0474
Schistosoma mansoni	nuclear hormone receptor	0.0232	0.3492	0.3492
Schistosoma mansoni	cathepsin F (C01 family)	0.0172	0.2415	0.2415
Mycobacterium leprae	conserved hypothetical protein	0.0036	0	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0232	0.3492	0.3492
Trypanosoma cruzi	cysteine peptidase, putative	0.0172	0.2415	0.2415
Onchocerca volvulus		0.0172	0.2415	0.6915
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0232	0.3492	0.3492
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0232	0.3492	0.3492
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.011	0.1305	0.1305
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0232	0.3492	0.3492
Brugia malayi	ecdysone receptor	0.011	0.1305	0.1305
Mycobacterium leprae	Probable lipase LipE	0.0036	0	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Mycobacterium ulcerans	hypothetical protein	0.0036	0	0.5
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0232	0.3492	0.3492
Echinococcus granulosus	calpain A	0.0191	0.2762	0.2762
Loa Loa (eye worm)	hypothetical protein	0.0232	0.3492	0.3492
Mycobacterium ulcerans	beta-lactamase	0.0036	0	0.5
Onchocerca volvulus	Cathepsin F homolog	0.0172	0.2415	0.6915
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Loa Loa (eye worm)	nuclear receptor NHR-67	0.011	0.1305	0.1305
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Schistosoma mansoni	Mername-AA248 (C02 family)	0.0066	0.0534	0.0534
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0175	0.0175
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Schistosoma mansoni	cathepsin F (C01 family)	0.0172	0.2415	0.2415
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Onchocerca volvulus		0.0172	0.2415	0.6915
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0264	0.0264
Trypanosoma cruzi	major cysteine proteinase, putative	0.0046	0.0166	0.0166
Loa Loa (eye worm)	fibroinase	0.0172	0.2415	0.2415
Giardia lamblia	Cathepsin B precursor	0.0216	0.3207	1
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0123	0.1539	0.1539
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0123	0.1539	0.1539
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Entamoeba histolytica	calpain large subunit domain III containing protein	0.0046	0.0179	0.006
Brugia malayi	nuclear receptor NHR-67	0.011	0.1305	0.1305
Trypanosoma cruzi	cruzipain precursor, putative	0.0172	0.2415	0.2415
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0232	0.3492	0.3492
Entamoeba histolytica	cysteine proteinase, putative	0.0121	0.1503	0.5946
Brugia malayi	Nuclear hormone receptor-like 1	0.0123	0.1539	0.1539
Trypanosoma cruzi	Aph-1 protein, putative	0.0092	0.0998	0.0998
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0046	0.0166	0.0166
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0232	0.3492	0.3492
Echinococcus multilocularis	Tolloid protein 1	0.0045	0.0148	0.0148
Trypanosoma brucei	antigen, putative	0.0066	0.0534	0.1666
Brugia malayi	nuclear hormone receptor family member odr-7	0.011	0.1305	0.1305
Plasmodium vivax	serine-repeat antigen 5 (SERA)	0.0046	0.0166	0.0686
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Leishmania major	cathepsin L-like protease	0.0172	0.2415	0.753
Trypanosoma brucei	kinesin, putative	0.0046	0.0179	0.0558
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Schistosoma mansoni	cathepsin s	0.0051	0.0264	0.0264
Echinococcus granulosus	Nuclear hormone receptor HR96	0.011	0.1305	0.1305
Trichomonas vaginalis	Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase	0.0046	0.0166	0.0516
Brugia malayi	nuclear receptor RXR	0.011	0.1305	0.1305
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0046	0.0166	0.0166
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0232	0.3492	0.3492
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0216	0.3207	1
Echinococcus multilocularis	cathepsin L cysteine protease	0.0172	0.2415	0.2415
Mycobacterium ulcerans	esterase/lipase LipP	0.0036	0	0.5
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Echinococcus multilocularis	calpain family protein 1, d	0.013	0.1659	0.1659
Trichomonas vaginalis	conserved hypothetical protein	0.0046	0.0166	0.0516
Echinococcus multilocularis	cathepsin b	0.0598	1	1
Leishmania major	cathepsin L-like protease	0.0172	0.2415	0.753
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0232	0.3492	0.3492
Onchocerca volvulus		0.011	0.1305	0.3738
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0046	0.0166	0.0516
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0046	0.0166	0.0516
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0097	0.1078	0.4054
Brugia malayi	Cathepsin L-like precursor	0.0121	0.1503	0.1503
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Schistosoma mansoni	retinoic acid receptor RXR	0.0232	0.3492	0.3492
Brugia malayi	Papain family cysteine protease containing protein	0.0097	0.1078	0.1078
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0121	0.1503	0.1503
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0172	0.2415	1
Onchocerca volvulus		0.0172	0.2415	0.6915
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0172	0.2415	0.2415
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0046	0.0166	0.0166
Loa Loa (eye worm)	ctsf protein	0.0172	0.2415	0.2415
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0232	0.3492	0.3492
Brugia malayi	Cathepsin L-like precursor	0.0172	0.2415	0.2415
Loa Loa (eye worm)	hypothetical protein	0.0123	0.1539	0.1539
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0175	0.0175
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0066	0.0534	0.0534
Loa Loa (eye worm)	hypothetical protein	0.0232	0.3492	0.3492
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Echinococcus granulosus	cathepsin b	0.0598	1	1
Trypanosoma brucei	calpain-like protein, putative	0.0066	0.0534	0.1666
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0123	0.1539	0.1539
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.011	0.1305	0.1305
Echinococcus granulosus	cathepsin L	0.0046	0.0166	0.0166
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0046	0.0166	0.0516
Loa Loa (eye worm)	hypothetical protein	0.0123	0.1539	0.1539
Entamoeba histolytica	cysteine proteinase 2	0.0097	0.1078	0.4054
Echinococcus multilocularis	cathepsin L	0.0046	0.0166	0.0166
Schistosoma mansoni	cathepsin C	0.0046	0.0166	0.0166
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0264	0.0264
Schistosoma mansoni	thyroid hormone receptor	0.0232	0.3492	0.3492
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0172	0.2415	0.753
Echinococcus granulosus	cathepsin l1	0.0172	0.2415	0.2415
Echinococcus granulosus	thyroid hormone receptor alpha	0.011	0.1305	0.1305
Plasmodium vivax	vivapain-1	0.0097	0.1078	0.4462
Echinococcus granulosus	calpain 5	0.0066	0.0534	0.0534
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0046	0.0166	0.0166
Loa Loa (eye worm)	hypothetical protein	0.0172	0.2415	0.2415
Mycobacterium ulcerans	lipase LipD	0.0036	0	0.5
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0046	0.0175	0.0175
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0172	0.2415	0.2415
Loa Loa (eye worm)	steroid hormone receptor	0.0232	0.3492	0.3492
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Leishmania major	cathepsin L-like protease	0.0172	0.2415	0.753
Brugia malayi	Papain family cysteine protease containing protein	0.0046	0.0166	0.0166
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0166	0.0166
Echinococcus granulosus	calpain A	0.0066	0.0534	0.0534
Entamoeba histolytica	protein kinase, putative	0.0046	0.0179	0.006
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0598	1	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0046	0.0166	0.0166
Schistosoma mansoni	family C2 unassigned peptidase (C02 family)	0.0176	0.2486	0.2486
Toxoplasma gondii	cathepsin B	0.0216	0.3207	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0046	0.0166	0.0166
Echinococcus granulosus	family C2 unassigned peptidase C02 family	0.0191	0.2753	0.2753
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0172	0.2415	0.753
Schistosoma mansoni	cathepsin F (C01 family)	0.0121	0.1503	0.1503
Loa Loa (eye worm)	hypothetical protein	0.0123	0.1539	0.1539
Brugia malayi	Nuclear hormone receptor-like 1	0.0123	0.1539	0.1539
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0123	0.1539	0.1539
Brugia malayi	hypothetical protein	0.0123	0.1539	0.1539
Loa Loa (eye worm)	hypothetical protein	0.013	0.1659	0.1659
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0066	0.0534	0.1666
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0172	0.2415	0.753
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0232	0.3492	0.3492
Trypanosoma cruzi	cysteine peptidase, putative	0.0172	0.2415	0.2415
Loa Loa (eye worm)	gamma-secretase subunit aph-1	0.0237	0.3576	0.3576
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0066	0.0534	0.0534
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0046	0.0166	0.0516
Trypanosoma brucei	Aph-1 protein, putative	0.0092	0.0998	0.3112
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0232	0.3492	0.3492
Brugia malayi	fibroinase precursor	0.0046	0.0166	0.0166
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0172	0.2415	0.2415
Echinococcus granulosus	gamma secretase subunit aph 1	0.0237	0.3576	0.3576
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0046	0.0175	0.0175
Loa Loa (eye worm)	hypothetical protein	0.0598	1	1
Loa Loa (eye worm)	DR-78	0.011	0.1305	0.1305
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0216	0.3207	0.3207
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0046	0.0166	0.0516
Brugia malayi	calpain family protein 1	0.0176	0.2486	0.2486
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0097	0.1078	0.1078
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0097	0.1078	0.1078
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0232	0.349	1
Trichomonas vaginalis	conserved hypothetical protein	0.0046	0.0166	0.0516
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0051	0.0264	0.0264
Leishmania major	cathepsin L-like protease	0.0172	0.2415	0.753
Toxoplasma gondii	cathepsin CPC2	0.0046	0.0166	0.0516
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0216	0.3207	0.3207
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0216	0.3207	1
Echinococcus multilocularis	cathepsin b	0.0598	1	1
Echinococcus multilocularis	cysteine protease	0.0172	0.2415	0.2415
Plasmodium vivax	dipeptidyl aminopeptidase 2, putative	0.0046	0.0166	0.0686
Onchocerca volvulus		0.0172	0.2415	0.6915
Plasmodium vivax	unspecified product	0.0097	0.1078	0.4462
Brugia malayi	nuclear receptor RXR	0.0123	0.1539	0.1539
Onchocerca volvulus		0.011	0.1305	0.3738
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Trypanosoma cruzi	cysteine peptidase, putative	0.0051	0.0264	0.0264
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0046	0.0166	0.0516
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0172	0.2415	0.2415
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0232	0.3492	0.3492
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0172	0.2415	0.753
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0166	0.0166
Schistosoma mansoni	calpain (C02 family)	0.0066	0.0534	0.0534
Echinococcus multilocularis	gamma secretase subunit aph 1	0.0237	0.3576	0.3576
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0046	0.0166	0.0516
Giardia lamblia	Cathepsin B precursor	0.0216	0.3207	1
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.011	0.1305	0.1305
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0166	0.0166
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0232	0.3492	0.3492
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.011	0.1305	0.3738
Onchocerca volvulus	Protein ultraspiracle homolog	0.0232	0.3492	1
Schistosoma mansoni	coup transcription factor	0.0232	0.3492	0.3492
Brugia malayi	Cathepsin L-like precursor	0.0172	0.2415	0.2415
Schistosoma mansoni	calpain-7 (C02 family)	0.0066	0.0534	0.0534
Loa Loa (eye worm)	hypothetical protein	0.0121	0.1503	0.1503
Brugia malayi	calpain 7	0.0066	0.0534	0.0534
Loa Loa (eye worm)	cysteine protease	0.0172	0.2415	0.2415
Toxoplasma gondii	cathepsin CPL	0.0172	0.2415	0.753
Echinococcus multilocularis	calpain A	0.0191	0.2762	0.2762
Onchocerca volvulus		0.0232	0.3492	1
Onchocerca volvulus	Cathepsin L homolog	0.0046	0.0166	0.0474
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.011	0.1305	0.1305
Echinococcus multilocularis	family C2 unassigned peptidase (C02 family)	0.0191	0.2753	0.2753
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0175	0.0175
Trypanosoma cruzi	cysteine peptidase, putative	0.0172	0.2415	0.2415
Schistosoma mansoni	zinc finger protein	0.011	0.1305	0.1305
Plasmodium vivax	serine-repeat antigen 2 (SERA)	0.0046	0.0166	0.0686
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0232	0.3492	0.3492
Onchocerca volvulus		0.0121	0.1503	0.4304
Schistosoma mansoni	family C2 unassigned peptidase (C02 family)	0.0191	0.2753	0.2753
Plasmodium vivax	serine-repeat antigen (SERA)	0.0046	0.0166	0.0686
Plasmodium vivax	vivapain-2	0.0172	0.2415	1
Schistosoma mansoni	nuclear hormone receptor	0.011	0.1305	0.1305
Echinococcus multilocularis	calpain	0.0066	0.0534	0.0534
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0097	0.1078	0.336
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.011	0.1305	0.1305
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0232	0.3492	0.3492
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0175	0.0175
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Toxoplasma gondii	cathepsin CPC1	0.0046	0.0166	0.0516
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0172	0.2415	1
Loa Loa (eye worm)	calpain	0.0066	0.0534	0.0534
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0598	1	1
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0046	0.0166	0.0166
Brugia malayi	cathepsin L-like cysteine proteinase	0.0046	0.0166	0.0166
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0232	0.3492	0.3492
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0232	0.3492	0.3492
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0232	0.3492	0.3492
Brugia malayi	Cathepsin L-like precursor	0.0172	0.2415	0.2415
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0066	0.0534	0.0534
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0232	0.3492	0.3492
Trypanosoma cruzi	major cysteine proteinase, putative	0.0046	0.0166	0.0166
Schistosoma mansoni	cathepsin B (C01 family)	0.0046	0.0166	0.0166
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Brugia malayi	Steroid receptor seven-up type 2	0.0232	0.3492	0.3492
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0066	0.0534	0.0534
Brugia malayi	Cathepsin L-like precursor	0.0172	0.2415	0.2415
Brugia malayi	cathepsin L precursor	0.0046	0.0166	0.0166
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0216	0.3207	1
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0598	1	1
Brugia malayi	Nuclear hormone receptor E75	0.011	0.1305	0.1305
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0232	0.3492	0.3492
Entamoeba histolytica	cysteine proteinase, putative	0.0097	0.1078	0.4054
Loa Loa (eye worm)	hypothetical protein	0.0123	0.1539	0.1539
Plasmodium vivax	dipeptidyl aminopeptidase 1, putative	0.0046	0.0166	0.0686
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0232	0.3492	1
Brugia malayi	calpain family protein 1	0.0176	0.2486	0.2486
Trypanosoma cruzi	kinesin, putative	0.0046	0.0179	0.0179
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.011	0.1305	0.1305
Loa Loa (eye worm)	hypothetical protein	0.0232	0.3492	0.3492
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0066	0.0534	0.0534
Leishmania major	cysteine peptidase A (CPA)	0.0172	0.2415	0.753
Schistosoma mansoni	thyroid hormone receptor	0.0232	0.3492	0.3492
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.011	0.1305	0.1305
Plasmodium vivax	calpain, putative	0.0066	0.0534	0.2213
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0097	0.1078	0.336
Brugia malayi	nuclear hormone receptor family member nhr-6	0.011	0.1305	0.1305
Brugia malayi	nuclear receptor NHR-88	0.011	0.1305	0.1305
Loa Loa (eye worm)	hypothetical protein	0.0232	0.3492	0.3492
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0232	0.3492	0.3492
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0166	0.0166
Giardia lamblia	Cathepsin B precursor	0.0216	0.3207	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0172	0.2415	0.753
Brugia malayi	ecdysteroid receptor	0.0232	0.3492	0.3492
Schistosoma mansoni	nuclear receptor	0.011	0.1305	0.1305
Plasmodium vivax	serine-repeat antigen 4 (SERA)	0.0046	0.0166	0.0686
Loa Loa (eye worm)	hypothetical protein	0.0123	0.1539	0.1539
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0232	0.3492	0.3492
Echinococcus multilocularis	cathepsin L	0.0097	0.1078	0.1078
Onchocerca volvulus	Cathepsin L homolog	0.0172	0.2415	0.6915
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0123	0.1539	0.1539
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0172	0.2415	0.753
Trypanosoma brucei	calpain-like protein, putative	0.0066	0.0534	0.1666
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Toxoplasma gondii	preprocathepsin c precursor, putative	0.0046	0.0166	0.0516
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0598	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0066	0.0534	0.0534
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0046	0.0166	0.0516
Brugia malayi	Nuclear hormone receptor E75	0.011	0.1305	0.1305
Echinococcus granulosus	nuclear receptor nhr 48	0.011	0.1305	0.1305
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.011	0.1305	0.1305
Brugia malayi	photoreceptor-specific nuclear receptor	0.0232	0.3492	0.3492
Brugia malayi	tailless protein	0.011	0.1305	0.1305
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0232	0.3492	0.3492
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0172	0.2415	0.753
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0066	0.0534	0.0534
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Loa Loa (eye worm)	hypothetical protein	0.0232	0.3492	0.3492
Plasmodium vivax	vivapain-3	0.0097	0.1078	0.4462
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0097	0.1078	0.336
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0264	0.0264
Brugia malayi	Cathepsin L-like precursor	0.0121	0.1503	0.1503
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0066	0.0534	0.0534
Trichomonas vaginalis	Clan CA, family C1, cathepsin F-like cysteine peptidase	0.0046	0.0166	0.0516
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0046	0.0166	0.0166
Leishmania major	cathepsin L-like protease	0.0172	0.2415	0.753
Brugia malayi	orphan nuclear receptor NR2E1	0.011	0.1305	0.1305
Loa Loa (eye worm)	hypothetical protein	0.0121	0.1503	0.1503
Trypanosoma cruzi	calpain cysteine peptidase, putative	0.0066	0.0534	0.0534
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Echinococcus granulosus	calpain	0.0066	0.0534	0.0534
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0097	0.1078	0.336
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0046	0.0166	0.0166
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0121	0.1503	0.4687
Onchocerca volvulus		0.0172	0.2415	0.6915
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0066	0.0534	0.1666
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0172	0.2415	0.2415
Echinococcus granulosus	calpain 7 C02 family	0.0066	0.0534	0.0534
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.0066	0.0534	0.1666
Brugia malayi	gamma-secretase subunit aph-1	0.0237	0.3576	0.3576
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0116	0.0116
Loa Loa (eye worm)	hypothetical protein	0.0232	0.3492	0.3492
Onchocerca volvulus	Bile acid receptor homolog	0.0232	0.3492	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0046	0.0166	0.0516
Brugia malayi	steroid hormone receptor	0.0232	0.3492	0.3492
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0232	0.3492	0.3492
Trypanosoma brucei	calpain-like protein, putative	0.0066	0.0534	0.1666
Trypanosoma brucei	calpain-like protein, putative	0.0066	0.0534	0.1666
Loa Loa (eye worm)	cathepsin B	0.0216	0.3207	0.3207
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0232	0.3492	0.3492
Trypanosoma cruzi	cysteine peptidase, putative	0.0097	0.1078	0.1078
Brugia malayi	conserved hypotetical protein	0.011	0.1305	0.1305
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Plasmodium vivax	unspecified product	0.0046	0.0166	0.0686
Echinococcus granulosus	Nuclear hormone receptor HR96	0.011	0.1305	0.1305
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0232	0.3492	0.3492
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0232	0.3492	0.3492
Leishmania major	cathepsin L-like protease	0.0172	0.2415	0.753
Brugia malayi	Cathepsin L-like precursor	0.0051	0.0264	0.0264
Trypanosoma cruzi	Aph-1 protein, putative	0.0092	0.0998	0.0998
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0172	0.2415	0.2415
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0175	0.0175
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0046	0.0166	0.0686
Echinococcus multilocularis	ecdysone induced protein 78C	0.0232	0.3492	0.3492
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0166	0.0166
Echinococcus granulosus	FTZ F1 alpha	0.0232	0.3492	0.3492
Onchocerca volvulus		0.011	0.1304	0.3733
Echinococcus multilocularis	calpain 5	0.0066	0.0534	0.0534
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0232	0.3492	0.3492
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0166	0.0166
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.011	0.1305	0.1305
Brugia malayi	nuclear hormone receptor	0.011	0.1305	0.1305
Leishmania major	kinesin, putative	0.0046	0.0179	0.0558
Schistosoma mansoni	RAR-like nuclear receptor	0.0232	0.3492	0.3492
Brugia malayi	Papain family cysteine protease containing protein	0.0046	0.0166	0.0166
Brugia malayi	Cathepsin L-like precursor	0.0172	0.2415	0.2415
Loa Loa (eye worm)	hypothetical protein	0.011	0.1305	0.1305
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0172	0.2415	0.753
Leishmania major	cathepsin L-like protease	0.0172	0.2415	0.753
Schistosoma mansoni	cathepsin S (C01 family)	0.0046	0.0166	0.0166
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Schistosoma mansoni	family C2 unassigned peptidase (C02 family)	0.0191	0.2753	0.2753
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0046	0.0166	0.0516
Loa Loa (eye worm)	hypothetical protein	0.0232	0.3492	0.3492
Entamoeba histolytica	cysteine proteinase, putative	0.0097	0.1078	0.4054
Brugia malayi	calpain 5	0.0046	0.0179	0.0179
Echinococcus multilocularis	FTZ F1 alpha	0.0232	0.3492	0.3492
Brugia malayi	hypothetical protein	0.0123	0.1539	0.1539
Trypanosoma cruzi	cysteine peptidase, putative	0.0172	0.2415	0.2415
Brugia malayi	cathepsin L-like precursor	0.0121	0.1503	0.1503
Echinococcus multilocularis	calpain 7 (C02 family)	0.0066	0.0534	0.0534
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.0046	0.0166	0.0686
Brugia malayi	hypothetical protein	0.011	0.1305	0.1305
Trypanosoma cruzi	cysteine proteinase, putative	0.0097	0.1078	0.1078
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0232	0.3492	0.3492
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0046	0.0166	0.0166
Loa Loa (eye worm)	hypothetical protein	0.0156	0.213	0.213
Loa Loa (eye worm)	calpain family protein 1	0.0176	0.2486	0.2486
Brugia malayi	Papain family cysteine protease containing protein	0.0097	0.1078	0.1078
Entamoeba histolytica	cysteine protease, putative	0.0172	0.2415	1
Brugia malayi	Nuclear hormone receptor-like 1	0.0232	0.3492	0.3492
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0172	0.2415	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0172	0.2415	0.753
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0232	0.3492	0.3492
Schistosoma mansoni	calpain-7 (C02 family)	0.0066	0.0534	0.0534
Plasmodium vivax	vivapain-2	0.0172	0.2415	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0121	0.1503	0.4687
Brugia malayi	hypothetical protein	0.011	0.1305	0.1305
Schistosoma mansoni	nuclear hormone receptor	0.011	0.1305	0.1305
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0232	0.3492	0.3492
Schistosoma mansoni	subfamily M12A unassigned peptidase (M12 family)	0.0045	0.0148	0.0148
Echinococcus granulosus	Tolloid protein 1	0.0045	0.0148	0.0148
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0046	0.0166	0.0166
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0097	0.1078	0.1078
Echinococcus granulosus	ecdysone induced protein 78C	0.0232	0.3492	0.3492
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0066	0.0534	0.1666
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0046	0.0166	0.0166
Loa Loa (eye worm)	calpain 5	0.0046	0.0179	0.0179
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0046	0.0166	0.0166
Echinococcus multilocularis	nuclear receptor nhr 48	0.011	0.1305	0.1305
Echinococcus granulosus	cathepsin L cysteine protease	0.0097	0.1078	0.1078
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0172	0.2415	0.753
Entamoeba histolytica	cysteine proteinase, putative	0.0097	0.1078	0.4054
Echinococcus multilocularis	cathepsin L cysteine protease	0.0172	0.2415	0.2415
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0172	0.2415	0.753
Loa Loa (eye worm)	calpain family protein 1	0.013	0.1659	0.1659
Loa Loa (eye worm)	hypothetical protein	0.011	0.1304	0.1304
Echinococcus granulosus	cathepsin b	0.0598	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0046	0.0166	0.0516
Loa Loa (eye worm)	hypothetical protein	0.0121	0.1503	0.1503
Trypanosoma cruzi	cysteine proteinase, putative	0.0097	0.1078	0.1078
Brugia malayi	Papain family cysteine protease containing protein	0.0046	0.0166	0.0166
Loa Loa (eye worm)	nuclear hormone receptor	0.011	0.1305	0.1305
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0097	0.1078	0.1078
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0232	0.3492	0.3492
Echinococcus multilocularis	hypothetical protein	0.0066	0.0534	0.0534
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0175	0.0175
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0172	0.2415	0.753
Entamoeba histolytica	cysteine protease, putative	0.0097	0.1078	0.4054
Trypanosoma cruzi	cysteine protease, putative	0.0097	0.1078	0.1078
Trypanosoma cruzi	kinesin, putative	0.0046	0.0179	0.0179
Echinococcus granulosus	cathepsin l1	0.0121	0.1503	0.1503
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or H-like cysteine peptidase	0.0046	0.0166	0.0516

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1789804

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1571374