Detailed information for compound 157292

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 306.261 | Formula: C11H9F3N2O3S
  • H donors: 0 H acceptors: 1 LogP: 3.05 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)Cn1c(=N)sc2c1ccc(c2)OC(F)(F)F
  • InChi: 1S/C11H9F3N2O3S/c1-18-9(17)5-16-7-3-2-6(19-11(12,13)14)4-8(7)20-10(16)15/h2-4,15H,5H2,1H3
  • InChiKey: OTDIGRNSFZGKOI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0304 0.0307 0.3997
Loa Loa (eye worm) hypothetical protein 0.0582 0.0615 0.0615
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Brugia malayi Glutamate receptor 1 precursor 0.003 0.0005 0.0005
Plasmodium falciparum plasmepsin I 0.0038 0.0013 0.0151
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Mycobacterium ulcerans polyketide synthase Pks13 0.0117 0.01 0.2376
Brugia malayi hypothetical protein 0.0038 0.0013 0.0013
Loa Loa (eye worm) AGC/AKT protein kinase 0.0042 0.0018 0.0018
Toxoplasma gondii subtilisin SUB6 0.0399 0.0413 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0087 0.0133
Loa Loa (eye worm) DEAH box polypeptide 35 0.0033 0.0007 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0006 0.0006
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0038 0.0013 0.0013
Brugia malayi Trypsin-like protease protein 5 0.0029 0.0003 0.0003
Loa Loa (eye worm) sirtuin 4 0.0105 0.0087 0.0087
Schistosoma mansoni amine oxidase 0.0118 0.0102 0.0102
Mycobacterium tuberculosis Conserved hypothetical protein 0.0118 0.0102 0.234
Brugia malayi hypothetical protein 0.0038 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0039 0.0015 0.0015
Loa Loa (eye worm) glutamate receptor 1 0.003 0.0005 0.0005
Schistosoma mansoni glutamate receptor NMDA 0.0257 0.0255 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0399 0.0413 0.0667
Plasmodium vivax NAD-dependent deacetylase, putative 0.0105 0.0087 0.1871
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0257 0.0255 0.0319
Plasmodium vivax subtilisin-like protease 2, putative 0.0399 0.0413 0.938
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0003 0.0003
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0118 0.0102 0.2208
Mycobacterium ulcerans NAD-dependent deacetylase 0.0105 0.0087 0.2059
Brugia malayi CUB domain containing protein 0.0035 0.001 0.001
Trypanosoma cruzi subtilisin peptidase 0.0399 0.0413 0.5265
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0435 0.0452 0.5924
Brugia malayi hypothetical protein 0.0304 0.0307 0.0307
Loa Loa (eye worm) apoptosis regulator protein 0.0054 0.0031 0.0031
Brugia malayi Trypsin family protein 0.0029 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Echinococcus multilocularis integrin beta 2 0.0491 0.0514 0.0642
Brugia malayi Trypsin family protein 0.0029 0.0003 0.0003
Plasmodium vivax subtilisin-like protease 1 0.0399 0.0413 0.938
Brugia malayi Stress-activated protein kinase jnk-1 0.0224 0.0218 0.0218
Toxoplasma gondii type I fatty acid synthase, putative 0.0082 0.0062 0.1501
Loa Loa (eye worm) transcriptional regulator 0.0105 0.0087 0.0087
Brugia malayi Integrin beta pat-3 precursor 0.0666 0.0708 0.0708
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0105 0.0087 0.0087
Echinococcus granulosus lysine specific histone demethylase 1A 0.0582 0.0615 0.0615
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2208 0.2413 0.3946
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.5545 0.6104 1
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0103 0.0085 0.0085
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0109 0.0092 0.0877
Onchocerca volvulus 0.0101 0.0083 0.1204
Brugia malayi Trypsin family protein 0.0029 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0631 0.0669 0.0669
Mycobacterium ulcerans polyketide synthase 0.0082 0.0062 0.1441
Echinococcus multilocularis Tolloid protein 1 0.0062 0.0039 0.0049
Brugia malayi CUB domain containing protein 0.0035 0.001 0.001
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0045 0.002 0.002
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0077 0.0056 0.0777
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0304 0.0307 0.0307
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0399 0.0413 0.0413
Schistosoma mansoni chromatin regulatory protein sir2 0.0105 0.0087 0.0087
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0022 0.0022
Schistosoma mansoni chromatin regulatory protein sir2 0.0712 0.0759 0.0759
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0712 0.0759 1
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0399 0.0413 1
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Entamoeba histolytica protein kinase, putative 0.0042 0.0018 0.0158
Echinococcus multilocularis expressed protein 0.0371 0.0381 0.0476
Toxoplasma gondii aspartyl protease 0.0038 0.0013 0.0307
Loa Loa (eye worm) hypothetical protein 0.0049 0.0025 0.0025
Onchocerca volvulus 0.0035 0.001 0.0111
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0399 0.0413 0.0516
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.5545 0.6104 0.6104
Brugia malayi Nematode astacin protease protein 30 0.0035 0.001 0.001
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0022 0.0028
Loa Loa (eye worm) hypothetical protein 0.0042 0.0018 0.0018
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0004 0.0006
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0582 0.0615 0.0615
Schistosoma mansoni discoidin domain receptor 0.0053 0.003 0.003
Echinococcus multilocularis 0.726 0.8 1
Trypanosoma cruzi UDP-galactopyranose mutase 0.0118 0.0102 0.101
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0053 0.003 0.0039
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0022 0.0028
Brugia malayi Probable ATP-dependent helicase DHX35 0.0033 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0035 0.001 0.001
Echinococcus granulosus adam 0.0068 0.0046 0.0046
Schistosoma mansoni amine oxidase 0.0118 0.0102 0.0102
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0003 0.0003
Loa Loa (eye worm) fatty acid synthase 0.0079 0.0058 0.0058
Onchocerca volvulus 0.0038 0.0013 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Plasmodium vivax aspartyl protease, putative 0.0038 0.0013 0.0151
Echinococcus multilocularis glycoprotein Antigen 5 0.0029 0.0003 0.0004
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0046 0.0022 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0105 0.0087 0.1981
Loa Loa (eye worm) hypothetical protein 0.0103 0.0085 0.0085
Echinococcus multilocularis c4b binding protein beta chain 0.0038 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0101 0.0083 0.0083
Echinococcus multilocularis neuropilin (nrp) and tolloid (tll) 0.0035 0.001 0.0013
Schistosoma mansoni memapsin-2 (A01 family) 0.0038 0.0013 0.0013
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0304 0.0307 0.3997
Loa Loa (eye worm) proprotein convertase 2 0.2208 0.2413 0.2413
Mycobacterium leprae PROBABLE CONSERVED TRANSMEMBRANE PROTEIN 0.0053 0.003 0.0087
Schistosoma mansoni tyrosine kinase 0.0677 0.072 0.072
Schistosoma mansoni protein arginine n-methyltransferase 0.0109 0.0092 0.0092
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2208 0.2413 0.3946
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0105 0.0087 0.1078
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0078 0.0057 0.1247
Echinococcus multilocularis chromatin regulatory protein sir2 0.0712 0.0759 0.0949
Echinococcus multilocularis MAM 0.0101 0.0083 0.0104
Echinococcus granulosus tissue type plasminogen activator 0.0052 0.0028 0.0028
Schistosoma mansoni c4b-binding protein beta chain 0.0038 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0029 0.0003 0.0003
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0054 0.0031 0.0031
Brugia malayi hypothetical protein 0.0038 0.0013 0.0013
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0712 0.0759 0.0759
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0105 0.0087 0.017
Toxoplasma gondii subtilisin SUB9 0.0399 0.0413 1
Brugia malayi hypothetical protein 0.0101 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0035 0.001 0.001
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0058 0.0035 0.0685
Echinococcus multilocularis cubilin 0.0035 0.001 0.0013
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.1808 0.1971 0.3222
Schistosoma mansoni hypothetical protein 0.0054 0.0031 0.0031
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0052 0.0028 0.0028
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.9068 1 1
Schistosoma mansoni growth factor receptor-bound protein 0.0136 0.0122 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Brugia malayi celfurPC protein 0.726 0.8 0.8
Loa Loa (eye worm) aspartyl protease 6 0.0038 0.0013 0.0013
Trypanosoma brucei subtilisin peptidase 0.0399 0.0413 0.5403
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0006 0.0008
Leishmania major arginine N-methyltransferase-like protein 0.0194 0.0186 0.2388
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0078 0.0057 0.5
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0062 0.0039 0.0885
Plasmodium vivax plasmepsin V, putative 0.0424 0.044 1
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0399 0.0413 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0013 0.0013
Schistosoma mansoni glutamate receptor kainate 0.003 0.0005 0.0005
Echinococcus multilocularis growth factor receptor bound protein 2 0.0136 0.0122 0.0152
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0223 0.0217 0.0217
Onchocerca volvulus 0.0052 0.0028 0.0377
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0105 0.0087 0.0109
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0006 0.0148
Schistosoma mansoni dock 0.0053 0.003 0.003
Plasmodium vivax apical sushi protein, putative 0.0038 0.0013 0.0169
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0054 0.0031 0.0031
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0038 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0029 0.0003 0.0003
Echinococcus multilocularis transmembrane protease serine 3 0.0029 0.0003 0.0004
Brugia malayi transcriptional regulator, Sir2 family protein 0.0712 0.0759 0.0759
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0082 0.0062 0.1358
Trypanosoma cruzi UDP-galactopyranose mutase 0.0118 0.0102 0.101
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Plasmodium falciparum plasmepsin VIII, putative 0.0038 0.0013 0.0151
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Brugia malayi hypothetical protein 0.0038 0.0013 0.0013
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0045 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0025 0.0032
Mycobacterium tuberculosis Probable thioesterase TesA 0.0067 0.0045 0.0936
Brugia malayi hypothetical protein 0.0038 0.0013 0.0013
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0109 0.0092 0.1142
Echinococcus granulosus nmda type glutamate receptor 0.0109 0.0091 0.0091
Brugia malayi Angiotensin-converting enzyme family protein 0.0672 0.0714 0.0714
Schistosoma mansoni glutamate receptor AMPA 0.003 0.0005 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2208 0.2413 0.3946
Loa Loa (eye worm) CUB domain-containing protein 0.0035 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.3523 0.3867 0.3867
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0029 0.0003 0.0003
Toxoplasma gondii kringle domain-containing protein 0.0052 0.0028 0.0678
Echinococcus granulosus glutamate receptor 2 0.0046 0.0022 0.0022
Echinococcus granulosus protein arginine methyltransferase 0.0194 0.0186 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0018 0.0019
Echinococcus multilocularis glutamate receptor 2 0.003 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0035 0.001 0.001
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0087 0.0133
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0109 0.0092 0.0092
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0013 0.0013
Echinococcus granulosus glutamate receptor ionotropic kainate 0.003 0.0005 0.0005
Brugia malayi hypothetical protein 0.0103 0.0085 0.0085
Mycobacterium leprae Probable polyketide synthase Pks1 0.0082 0.0062 0.0919
Echinococcus granulosus membrane bound transcription factor site 1 0.0399 0.0413 0.0413
Toxoplasma gondii rhoptry neck protein RON9 0.0038 0.0013 0.0326
Schistosoma mansoni site-1 peptidase (S08 family) 0.0399 0.0413 0.0413
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Echinococcus multilocularis glutamate receptor 2 0.0046 0.0022 0.0028
Schistosoma mansoni furin-1 (S08 family) 0.3922 0.4309 0.4309
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.003 0.0005 0.0005
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0118 0.0102 0.2208
Giardia lamblia Hypothetical protein 0.0712 0.0759 0.2017
Toxoplasma gondii subtilisin SUB12 0.0399 0.0413 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2208 0.2413 0.3946
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0117 0.01 0.2301
Toxoplasma gondii F5/8 type C domain-containing protein 0.0053 0.003 0.0722
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0058 0.0036 0.0036
Toxoplasma gondii histone deacetylase SIR2 0.0105 0.0087 0.2114
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0045 0.002 0.002
Brugia malayi Nematode astacin protease protein 30 0.0035 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0101 0.0083 0.0083
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0139 0.0124 0.0124
Loa Loa (eye worm) WD40 repeat protein 0.0278 0.0278 0.0278
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.5545 0.6104 1
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0118 0.0102 0.0102
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0062 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.001 0.001
Onchocerca volvulus 0.0035 0.001 0.0111
Brugia malayi Sushi domain 0.0038 0.0013 0.0013
Loa Loa (eye worm) integrin beta-2 0.0666 0.0708 0.0708
Toxoplasma gondii type I fatty acid synthase, putative 0.0057 0.0034 0.0825
Toxoplasma gondii PA14 domain-containing protein 0.0053 0.003 0.0722
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0082 0.0062 0.1358
Loa Loa (eye worm) transcriptional regulator 0.0712 0.0759 0.0759
Loa Loa (eye worm) zinc metalloproteinase toh-2 0.0035 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.9068 1 1
Leishmania major UDP-galactopyranose mutase 0.0118 0.0102 0.1271
Leishmania major arginine N-methyltransferase, type I 0.0109 0.0092 0.1142
Plasmodium falciparum plasmepsin X 0.0038 0.0013 0.0151
Onchocerca volvulus 0.0038 0.0013 0.0147
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0022 0.0022
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0682 0.0726 0.0726
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0075 0.0054 0.1156
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0077 0.0056 0.1222
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0007
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0081 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0149 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0052 0.0028 0.0028
Brugia malayi Kringle domain containing protein 0.0052 0.0028 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Loa Loa (eye worm) hypothetical protein 0.0058 0.0035 0.0035
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0087 0.0133
Trichomonas vaginalis hypothetical protein 0.1808 0.1971 0.3222
Echinococcus granulosus c4b binding protein beta chain 0.0038 0.0013 0.0013
Plasmodium falciparum plasmepsin V 0.0424 0.044 1
Echinococcus multilocularis enteropeptidase 0.0029 0.0003 0.0004
Toxoplasma gondii subtilisin SUB10 0.0399 0.0413 1
Brugia malayi Subtilase family protein 0.0399 0.0413 0.0413
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0029 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0101 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0035 0.001 0.001
Giardia lamblia Sirtuin type 2 0.0105 0.0087 0.017
Loa Loa (eye worm) Carm1-pending protein 0.0109 0.0092 0.0092
Schistosoma mansoni hypothetical protein 0.0109 0.0092 0.0092
Mycobacterium ulcerans polyketide synthase 0.0077 0.0056 0.1307
Schistosoma mansoni ATP-binding cassette transporter 0.003 0.0005 0.0005
Entamoeba histolytica PH domain containing protein kinase, putative 0.0078 0.0057 0.0678
Toxoplasma gondii aspartyl protease ASP3 0.0038 0.0013 0.0307
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.0056 0.1307
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0194 0.0186 0.0295
Schistosoma mansoni cathepsin D (A01 family) 0.0038 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0042 0.0018 0.0018
Brugia malayi Sex muscle abnormal protein 5 0.0136 0.0122 0.0122
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0046 0.0022 0.0022
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0109 0.0092 0.0092
Schistosoma mansoni glutamate receptor kainate 0.003 0.0005 0.0005
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0046 0.0021 0.0358
Brugia malayi Glutamate receptor 2 precursor 0.003 0.0005 0.0005
Brugia malayi CUB domain containing protein 0.0039 0.0015 0.0015
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0045 0.002 0.0025
Onchocerca volvulus 0.0035 0.001 0.0111
Brugia malayi Protein kinase domain containing protein 0.0042 0.0018 0.0018
Brugia malayi p70 ribosomal S6 kinase beta 0.0041 0.0016 0.0016
Brugia malayi SWIRM domain containing protein 0.0049 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Brugia malayi aspartic protease BmAsp-1, identical 0.0038 0.0013 0.0013
Brugia malayi pregnancy-associated plasma protein-A 0.0038 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0105 0.0087 0.0087
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0109 0.0092 0.1142
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.003 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0018 0.0019
Echinococcus multilocularis neuroendocrine convertase 2 0.573 0.6309 0.7886
Brugia malayi Kelch motif family protein 0.0139 0.0124 0.0124
Echinococcus granulosus glycoprotein Antigen 5 0.0029 0.0003 0.0003
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0052 0.0028 0.0504
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0218 0.0218
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0109 0.0092 0.0877
Loa Loa (eye worm) glutamate receptor 2 0.003 0.0005 0.0005
Mycobacterium ulcerans oxidoreductase 0.0118 0.0102 0.2414
Toxoplasma gondii aspartyl protease ASP1 0.0038 0.0013 0.0307
Loa Loa (eye worm) hypothetical protein 0.0157 0.0145 0.0145
Onchocerca volvulus 0.0053 0.003 0.0404
Brugia malayi zinc metalloproteinase toh-2 precursor 0.0035 0.001 0.001
Toxoplasma gondii subtilisin SUB7 0.0399 0.0413 1
Brugia malayi transcriptional regulator, Sir2 family protein 0.0105 0.0087 0.0087
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0078 0.0057 0.1233
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0399 0.0413 1
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0078 0.0057 0.1233
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.003 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Onchocerca volvulus 0.0038 0.0013 0.0159
Schistosoma mansoni btb and poz domain-containing protein 0.0053 0.003 0.003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2208 0.2413 0.3946
Toxoplasma gondii subtilisin SUB8 0.0399 0.0413 1
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0109 0.0092 0.0877
Mycobacterium tuberculosis Possible oxidoreductase 0.0118 0.0102 0.234
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.004 0.0016 0.0382
Onchocerca volvulus 0.0038 0.0013 0.0159
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0082 0.0062 0.1358
Leishmania major silent information regulator 2, putative 0.0712 0.0759 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Echinococcus multilocularis discoidin domain containing receptor 2 0.0053 0.003 0.0037
Onchocerca volvulus 0.0631 0.0669 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0254 0.0252 0.0316
Loa Loa (eye worm) hypothetical protein 0.0062 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0003
Onchocerca volvulus 0.0075 0.0054 0.0764
Plasmodium falciparum plasmepsin VI 0.0038 0.0013 0.0151
Echinococcus granulosus furin 0.9068 1 1
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0105 0.0087 0.1871
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0399 0.0413 1
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Echinococcus multilocularis membrane bound transcription factor site 1 0.0399 0.0413 0.0516
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.0056 0.1307
Mycobacterium ulcerans dehydrogenase 0.0118 0.0102 0.2414
Schistosoma mansoni hypothetical protein 0.1808 0.1971 0.1971
Onchocerca volvulus 0.0194 0.0186 0.2744
Plasmodium vivax hypothetical protein, conserved 0.0105 0.0087 0.1871
Echinococcus granulosus glutamate NMDA receptor subunit 0.0257 0.0255 0.0255
Brugia malayi Protein arginine N-methyltransferase 0.0109 0.0092 0.0092
Brugia malayi Protein kinase domain containing protein 0.0052 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0399 0.0413 0.0667
Echinococcus granulosus CUB 0.0035 0.001 0.001
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0038 0.0013 0.0307
Entamoeba histolytica hypothetical protein 0.0304 0.0307 0.3997
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0582 0.0615 0.0769
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0013 0.0013
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Brugia malayi Zinc metalloproteinase toh-2 precursor 0.0035 0.001 0.001
Giardia lamblia High cysteine membrane protein Group 2 0.3337 0.3662 1
Brugia malayi proprotein convertase 2 0.573 0.6309 0.6309
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0435 0.0452 0.5802
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0712 0.0759 1
Echinococcus granulosus enteropeptidase 0.0029 0.0003 0.0003
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0003 0.0004
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0118 0.0102 0.2208
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0194 0.0186 0.0186
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0035 0.001 0.001
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0105 0.0087 0.0087
Plasmodium falciparum subtilisin-like protease 2 0.0399 0.0413 0.938
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0672 0.0714 0.0714
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Toxoplasma gondii subtilisin SUB5 0.0399 0.0413 1
Onchocerca volvulus 0.0278 0.0278 0.4133
Loa Loa (eye worm) hypothetical protein 0.0045 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0101 0.0083 0.0083
Echinococcus granulosus discoidin domain containing receptor 2 0.0053 0.003 0.003
Toxoplasma gondii aspartyl protease ASP5 0.0386 0.0398 0.9641
Plasmodium vivax hypothetical protein, conserved 0.0118 0.0102 0.2208
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0118 0.0102 0.2414
Mycobacterium tuberculosis Possible arabinofuranosyltransferase AftD 0.0053 0.003 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0085 0.0085
Plasmodium falciparum plasmepsin VII 0.0038 0.0013 0.0151
Schistosoma mansoni hypothetical protein 0.0054 0.0031 0.0031
Plasmodium falciparum LCCL domain-containing protein 0.0053 0.003 0.0546
Echinococcus multilocularis adam 0.0068 0.0046 0.0058
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0003
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0054 0.0031 0.0039
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0087 0.0133
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0194 0.0186 0.4504
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Loa Loa (eye worm) hypothetical protein 0.0118 0.0102 0.0102
Schistosoma mansoni protein kinase 0.0254 0.0252 0.0252
Echinococcus multilocularis Coagulation factor 5 8 type, C terminal 0.0053 0.003 0.0037
Mycobacterium leprae Polyketide synthase Pks13 0.0117 0.01 0.191
Brugia malayi GCC2 and GCC3 family protein 0.0058 0.0035 0.0035
Trypanosoma brucei SIR2-like protein 4, putative 0.0105 0.0087 0.1078
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0082 0.0062 0.0919
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Echinococcus granulosus cubilin 0.0035 0.001 0.001
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Echinococcus multilocularis SWI:SNF complex subunit SMARCC2 0.0049 0.0025 0.0032
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0053 0.003 0.0039
Schistosoma mansoni chromatin regulatory protein sir2 0.0105 0.0087 0.0087
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0712 0.0759 0.1235
Loa Loa (eye worm) hypothetical protein 0.0118 0.0102 0.0102
Plasmodium vivax aspartyl proteinase, putative 0.0038 0.0013 0.0151
Mycobacterium ulcerans Sir2-like regulatory protein 0.0105 0.0087 0.2059
Echinococcus granulosus integrin beta 2 0.0491 0.0514 0.0514
Echinococcus multilocularis discoidin domain containing receptor 2 0.0053 0.003 0.0037
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0109 0.0092 0.0115
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0105 0.0087 0.0109
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0118 0.0102 0.2208
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0006 0.0006
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0077 0.0056 0.1222
Mycobacterium ulcerans thioesterase TesA 0.0067 0.0045 0.1024
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0038 0.0013 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0399 0.0413 0.0413
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Echinococcus granulosus growth factor receptor bound protein 2 0.0136 0.0122 0.0122
Schistosoma mansoni atypical protein kinase C 0.0027 0.0001 0.0001
Toxoplasma gondii subtilisin SUB1 0.0399 0.0413 1
Brugia malayi hypothetical protein 0.0038 0.0013 0.0013
Brugia malayi hypothetical protein 0.0029 0.0003 0.0003
Plasmodium falciparum LCCL domain-containing protein 0.0053 0.003 0.0546
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0109 0.0092 0.0877
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0712 0.0759 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Schistosoma mansoni septate junction protein 0.0073 0.0052 0.0052
Brugia malayi SWIRM domain containing protein 0.0631 0.0669 0.0669
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.001 0.0007
Echinococcus granulosus cubilin 0.0035 0.001 0.001
Entamoeba histolytica protein kinase, putative 0.0033 0.0008 0.002
Giardia lamblia Furin precursor putative serine protease 0.1808 0.1971 0.5349
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0013 0.0013
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Toxoplasma gondii bicoid-interacting protein BIN3 0.0109 0.0092 0.223
Loa Loa (eye worm) hypothetical protein 0.0053 0.003 0.003
Entamoeba histolytica protein kinase, putative 0.0041 0.0016 0.0129
Onchocerca volvulus 0.0038 0.0013 0.0159
Echinococcus granulosus expressed protein 0.0371 0.0381 0.0381
Loa Loa (eye worm) CUB domain-containing protein 0.0035 0.001 0.001
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0399 0.0413 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.001 0.001
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0062 0.0039 0.0039
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0087 0.0133
Echinococcus multilocularis Mastin 0.0029 0.0003 0.0004
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0054 0.0031 0.0031
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0223 0.0217 0.0217
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Loa Loa (eye worm) hypothetical protein 0.003 0.0004 0.0004
Onchocerca volvulus Putative cubilin 0.0055 0.0032 0.0442
Brugia malayi hypothetical protein 0.0038 0.0013 0.0013
Echinococcus multilocularis NMDA receptor 0.003 0.0005 0.0006
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0077 0.0056 0.0777
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0105 0.0087 0.1871
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0077 0.0056 0.0056
Brugia malayi aspartic protease BmAsp-2, identical 0.0038 0.0013 0.0013
Brugia malayi hypothetical protein 0.0035 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0101 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0003
Echinococcus granulosus serine:threonine protein kinase N2 0.0076 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Loa Loa (eye worm) acyl carrier protein 0.0037 0.0012 0.0012
Onchocerca volvulus 0.0038 0.0013 0.0159
Schistosoma mansoni chromatin regulatory protein sir2 0.0105 0.0087 0.0087
Echinococcus multilocularis protoporphyrinogen oxidase 0.0118 0.0102 0.0127
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0105 0.0087 0.0811
Brugia malayi hypothetical protein 0.0058 0.0036 0.0036
Echinococcus granulosus protein arginine N methyltransferase 8 0.0194 0.0186 0.0186
Plasmodium falciparum plasmepsin II 0.0038 0.0013 0.0151
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0087 0.0133
Plasmodium vivax aspartyl protease, putative 0.0038 0.0013 0.0151
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0109 0.0092 0.0115
Plasmodium vivax subtilisin-like serine protease, putative 0.0399 0.0413 0.938
Mycobacterium ulcerans thioesterase 0.0067 0.0045 0.1024
Schistosoma mansoni hypothetical protein 0.0278 0.0278 0.0278
Plasmodium vivax plasmepsin IV, putative 0.0038 0.0013 0.0151
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0105 0.0087 0.0811
Echinococcus granulosus c-Jun N-terminal kinases 0.0224 0.0218 0.0218
Brugia malayi Cam kinase protein 1 0.0032 0.0006 0.0006
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0053 0.003 0.0039
Echinococcus granulosus glutamate receptor subunit protein glur 0.003 0.0005 0.0005
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0399 0.0413 0.0413
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Loa Loa (eye worm) hypothetical protein 0.0055 0.0032 0.0032
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0038 0.0013 0.0016
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0006 0.0006
Schistosoma mansoni chromatin regulatory protein sir2 0.0105 0.0087 0.0087
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0041 0.0016 0.0016
Echinococcus multilocularis protein kinase c epsilon type 0.0103 0.0085 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Entamoeba histolytica hypothetical protein, conserved 0.0105 0.0087 0.1078
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.0056 0.1307
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Echinococcus granulosus protein will die slowly 0.0278 0.0278 0.0278
Brugia malayi hypothetical protein 0.0118 0.0102 0.0102
Brugia malayi protein kinase C II. 0.0103 0.0085 0.0085
Echinococcus granulosus discoidin domain receptor 0.0053 0.003 0.003
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0194 0.0186 0.0295
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0399 0.0413 1
Echinococcus multilocularis fibrillin 1 0.0038 0.0014 0.0017
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0022 0.0028
Onchocerca volvulus 0.0038 0.0013 0.0147
Toxoplasma gondii subtilisin SUB11 0.0399 0.0413 1
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0194 0.0186 0.0186
Onchocerca volvulus 0.0038 0.0013 0.0159
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2208 0.2413 0.3946
Onchocerca volvulus 0.0038 0.0013 0.0159
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0118 0.0102 0.1951
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0035 0.001 0.001
Brugia malayi Eukaryotic aspartyl protease family protein 0.0038 0.0013 0.0013
Echinococcus multilocularis nmda type glutamate receptor 0.0109 0.0091 0.0114
Echinococcus granulosus protein kinase c iota type 0.0027 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0399 0.0413 0.0667
Echinococcus multilocularis glutamate receptor subunit protein glur 0.003 0.0005 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0054 0.0031 0.0031
Entamoeba histolytica SWIRM domain protein 0.0049 0.0025 0.0257
Echinococcus granulosus transmembrane protease serine 3 0.0029 0.0003 0.0003
Toxoplasma gondii rhoptry neck protein RON1 0.0038 0.0013 0.0326
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0078 0.0057 0.1332
Leishmania major sir2-family protein-like protein 0.0105 0.0087 0.1078
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0136 0.0122 0.0122
Brugia malayi Protein kinase domain containing protein 0.0101 0.0083 0.0083
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0006 0.0006
Trichomonas vaginalis hypothetical protein 0.0053 0.003 0.0039
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.003 0.0004 0.0004
Plasmodium falciparum plasmepsin III 0.0038 0.0013 0.0151
Brugia malayi neuroendocrine convertase 1 precursor 0.573 0.6309 0.6309
Loa Loa (eye worm) hypothetical protein 0.0399 0.0413 0.0413
Loa Loa (eye worm) transcriptional regulator 0.0105 0.0087 0.0087
Echinococcus granulosus MAM 0.0101 0.0083 0.0083
Brugia malayi Muscle positioning protein 4 0.0042 0.0017 0.0017
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0064 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0053 0.003 0.003
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0399 0.0413 0.5265
Onchocerca volvulus 0.0038 0.0013 0.0159
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0117 0.01 0.2301
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0006 0.0008
Brugia malayi amine oxidase, flavin-containing family protein 0.0168 0.0156 0.0156
Schistosoma mansoni hypothetical protein 0.0035 0.001 0.001
Echinococcus multilocularis epidermal growth factor receptor 0.0677 0.072 0.09
Echinococcus multilocularis serine:threonine protein kinase N2 0.0095 0.0076 0.0095
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0109 0.0091 0.0114
Loa Loa (eye worm) hypothetical protein 0.0035 0.001 0.001
Onchocerca volvulus 0.0053 0.003 0.0404
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0068 0.0046 0.0046
Echinococcus granulosus Mastin 0.0029 0.0003 0.0003
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0109 0.0092 0.0141
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0712 0.0759 0.0949
Brugia malayi Protein kinase domain containing protein 0.0053 0.003 0.003
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0087 0.0133
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1356 0.1471 0.1471
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0018 0.0019
Leishmania major subtilisin-like serine peptidase 0.0399 0.0413 0.5403
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0399 0.0413 1
Echinococcus multilocularis discoidin domain containing receptor 2 0.0053 0.003 0.0037
Echinococcus granulosus C type lectin domian containing protein 0.0038 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Echinococcus granulosus epidermal growth factor receptor 0.0677 0.072 0.072
Echinococcus multilocularis Furin 1 0.2208 0.2413 0.3016
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0003 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0006 0.0006
Echinococcus granulosus lysine specific histone demethylase 1A 0.0118 0.0102 0.0102
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0109 0.0092 0.223
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0029 0.0003 0.0003
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0052 0.0028 0.069
Trichomonas vaginalis conserved hypothetical protein 0.0399 0.0413 0.0667
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0118 0.0102 0.2467
Loa Loa (eye worm) hypothetical protein 0.0582 0.0615 0.0615
Brugia malayi Pepsin A precursor 0.0038 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0032 0.0006 0.0006
Schistosoma mansoni integrin beta subunit 0.0388 0.04 0.04
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0006 0.0006
Schistosoma mansoni chromatin regulatory protein sir2 0.0712 0.0759 0.0759
Brugia malayi Suppressor of lurcher protein 1 precursor 0.0035 0.001 0.001
Loa Loa (eye worm) TK/ROR protein kinase 0.0052 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0035 0.001 0.001
Plasmodium falciparum subtilisin-like protease 3 0.0399 0.0413 0.938
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0006 0.0006
Schistosoma mansoni apoptosis regulator bax 0.0054 0.0031 0.0031
Loa Loa (eye worm) reprolysin 0.0045 0.002 0.002
Echinococcus multilocularis tissue type plasminogen activator 0.0052 0.0028 0.0035
Toxoplasma gondii histone deacetylase SIR2-like 0.0105 0.0087 0.2114
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0038 0.0013 0.0011
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0399 0.0413 1
Trichomonas vaginalis conserved hypothetical protein 0.0399 0.0413 0.0667
Onchocerca volvulus Arrow homolog 0.003 0.0004 0.0023
Toxoplasma gondii subtilisin SUB4 0.0399 0.0413 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0013 0.0013
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0006 0.0148
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0082 0.0062 0.0919
Echinococcus granulosus Protein kinase C brain isozyme 0.0029 0.0003 0.0003
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0247 0.0244 0.0244
Loa Loa (eye worm) DPY-31 protein 0.0035 0.001 0.001
Echinococcus granulosus chromatin regulatory protein sir2 0.0712 0.0759 0.0759
Schistosoma mansoni chromatin regulatory protein sir2 0.0712 0.0759 0.0759
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.0017
Echinococcus granulosus methyltransferase protein 5 0.0109 0.0092 0.0092
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0304 0.0307 0.3817
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0006 0.0148
Plasmodium falciparum apical sushi protein 0.0038 0.0013 0.0169
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0013 0.0013
Brugia malayi CUB domain containing protein 0.0035 0.001 0.001
Echinococcus granulosus neuroendocrine convertase 2 0.573 0.6309 0.6309
Loa Loa (eye worm) TK/ALK protein kinase 0.0101 0.0083 0.0083
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0018 0.0019
Brugia malayi NAD-dependent deacetylase SIRT1 0.0105 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.0017
Chlamydia trachomatis protoporphyrinogen oxidase 0.0118 0.0102 1
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0018 0.0019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0003 0.0003
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0062 0.0039 0.0885
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0194 0.0186 0.4147
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0254 0.0252 0.0252
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0013 0.0013
Brugia malayi Lectin C-type domain containing protein 0.0035 0.001 0.001
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0035 0.001 0.001
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0109 0.0092 0.1142
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.005 0.0026 0.0575
Brugia malayi Furin-like cysteine rich region family protein 0.0677 0.072 0.072
Echinococcus multilocularis discoidin domain receptor 0.0053 0.003 0.0037
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0029 0.0003 0.0004
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0087 0.0133
Plasmodium vivax LCCL domain-containing protein 0.0053 0.003 0.0546
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0063 0.004 0.0824
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Echinococcus granulosus discoidin domain containing receptor 2 0.0053 0.003 0.003
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0077 0.0056 0.1222
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0194 0.0186 0.0232
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0006 0.0008
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0682 0.0726 0.0907
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.5545 0.6104 0.7629
Brugia malayi Calcium binding EGF domain containing protein 0.0055 0.0032 0.0032
Giardia lamblia Transcriptional regulator, Sir2 family 0.0105 0.0087 0.017
Leishmania major hypothetical protein, conserved 0.0052 0.0028 0.029
Onchocerca volvulus 0.0399 0.0413 0.6152
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.003 0.0005 0.0006
Schistosoma mansoni SWI/SNF complex-related 0.0049 0.0025 0.0025
Echinococcus multilocularis C type lectin domian containing protein 0.0038 0.0013 0.0017
Loa Loa (eye worm) trypsin family protein 0.0029 0.0003 0.0003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0003 0.0003
Echinococcus granulosus protein arginine N methyltransferase 7 0.0109 0.0092 0.0092
Brugia malayi hypothetical protein 0.0038 0.0013 0.0013
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.1808 0.1971 0.3222
Loa Loa (eye worm) endoprotease bli-4 0.9068 1 1
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0194 0.0186 0.4147
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0712 0.0759 1
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0109 0.0092 0.223
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0712 0.0759 0.1235
Brugia malayi Carm1-pending protein 0.0109 0.0092 0.0092
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.1808 0.1971 0.3222
Schistosoma mansoni growth factor receptor-bound protein 0.0136 0.0122 0.0122
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0105 0.0087 0.1078
Onchocerca volvulus 0.0101 0.0083 0.1204
Onchocerca volvulus 0.0139 0.0125 0.1836
Brugia malayi transcriptional regulator, Sir2 family protein 0.0105 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.0029 0.0003 0.0003
Onchocerca volvulus 0.0064 0.0042 0.0581
Plasmodium vivax aspartyl protease, putative 0.0038 0.0013 0.0151
Schistosoma mansoni site-1 peptidase (S08 family) 0.0399 0.0413 0.0413
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Schistosoma mansoni hypothetical protein 0.0054 0.0031 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0018 0.0019
Toxoplasma gondii AGC kinase 0.0041 0.0016 0.0383
Echinococcus granulosus SWI:SNF complex subunit SMARCC2 0.0049 0.0025 0.0025
Schistosoma mansoni discoidin domain receptor 0.0053 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0053 0.003 0.003
Plasmodium vivax aspartyl proteinase, putative 0.0038 0.0013 0.0151
Toxoplasma gondii SWIRM domain-containing protein 0.0049 0.0025 0.0617
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0399 0.0413 0.0413
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0105 0.0087 0.1078
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Echinococcus multilocularis CUB 0.0035 0.001 0.0013
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0109 0.0092 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.1808 0.1971 0.3222
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.003 0.0005 0.0006
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0105 0.0087 0.1078
Onchocerca volvulus 0.0035 0.001 0.0111
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0435 0.0452 0.5802
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0042 0.0018 0.0018
Echinococcus multilocularis protein kinase c iota type 0.0027 0.0001 0.0001
Toxoplasma gondii subtilisin SUB2 0.0399 0.0413 1
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0109 0.0092 0.0141
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0038 0.0013 0.0013
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0224 0.0218 0.0218
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0087 0.0133
Brugia malayi hypothetical protein 0.0038 0.0013 0.0013
Plasmodium vivax LCCL domain-containing protein 0.0053 0.003 0.0546
Echinococcus granulosus protein kinase c epsilon type 0.0103 0.0085 0.0085
Schistosoma mansoni cathepsin D (A01 family) 0.0038 0.0013 0.0013
Entamoeba histolytica SWIRM domain protein 0.0049 0.0025 0.0257
Plasmodium falciparum plasmepsin IX 0.0038 0.0013 0.0151
Echinococcus multilocularis protein arginine methyltransferase 0.0194 0.0186 0.0232
Mycobacterium ulcerans monoamine oxidase 0.0118 0.0102 0.2414
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.003 0.0005 0.0005
Mycobacterium leprae Possible secreted protease 0.0399 0.0413 1
Schistosoma mansoni hypothetical protein 0.0035 0.001 0.001
Plasmodium falciparum cysteine repeat modular protein 1 0.0052 0.0028 0.0504
Plasmodium vivax hypothetical protein, conserved 0.0118 0.0102 0.2208
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Entamoeba histolytica hypothetical protein 0.0049 0.0025 0.0257
Plasmodium falciparum protoporphyrinogen oxidase 0.0118 0.0102 0.2208
Loa Loa (eye worm) subtilase 0.0399 0.0413 0.0413
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0168 0.0156 0.0156
Onchocerca volvulus 0.0038 0.0013 0.0159
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0038 0.0013 0.0013
Schistosoma mansoni glutamate receptor kainate 0.003 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0067 0.0045 0.0476
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0054 0.0054
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0224 0.0218 0.0273
Plasmodium falciparum subtilisin-like protease 1 0.0399 0.0413 0.938
Trypanosoma brucei rac serine-threonine kinase, putative 0.0042 0.0018 0.0158
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0712 0.0759 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Onchocerca volvulus Fatty acid synthase homolog 0.0144 0.0131 0.1918
Plasmodium falciparum plasmepsin IV 0.0038 0.0013 0.0151
Echinococcus granulosus Tolloid protein 1 0.0062 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0025 0.0032
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.2208 0.2413 0.2413
Echinococcus multilocularis nuclear receptor 2C2 associated protein 0.0053 0.003 0.0037
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0078 0.0057 0.5
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0082 0.0062 0.1441
Onchocerca volvulus 0.0038 0.0013 0.0159
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0105 0.0087 0.0109
Loa Loa (eye worm) hypothetical protein 0.0035 0.001 0.001
Brugia malayi Will die slowly protein 0.0278 0.0278 0.0278
Schistosoma mansoni protein kinase 0.0254 0.0252 0.0252
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0075 0.0054 0.0054
Brugia malayi astacin protease protein 30 0.0035 0.001 0.001
Echinococcus granulosus neuropilin nrp and tolloid tll 0.0035 0.001 0.001
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0077 0.0056 0.1307
Echinococcus multilocularis cubilin 0.0035 0.001 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0003 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Mycobacterium ulcerans polyketide synthase Pks9 0.005 0.0026 0.0575
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0194 0.0186 0.0186
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0399 0.0413 0.0413
Echinococcus multilocularis protein will die slowly 0.0278 0.0278 0.0348
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0018 0.0019
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0082 0.0062 0.1441
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0304 0.0307 0.3817
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Echinococcus granulosus Furin 1 0.2208 0.2413 0.2413
Schistosoma mansoni protein kinase 0.0254 0.0252 0.0252
Echinococcus granulosus Coagulation factor 5 8 type C terminal 0.0053 0.003 0.003
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0118 0.0102 0.2414
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0013 0.0013
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0194 0.0186 0.0295
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0118 0.0102 0.2414
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0105 0.0087 0.0087
Brugia malayi CUB domain containing protein 0.0035 0.001 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0399 0.0413 0.0667
Brugia malayi Trypsin family protein 0.0029 0.0003 0.0003
Toxoplasma gondii histone lysine-specific demethylase 0.0118 0.0102 0.2467
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0399 0.0413 1
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.003 0.0039
Loa Loa (eye worm) TK/EGFR protein kinase 0.0677 0.072 0.072
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0003 0.0003
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0029 0.0003 0.0003
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0013 0.0013
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0062 0.0039 0.0329
Echinococcus multilocularis 0.0118 0.0102 0.0127
Toxoplasma gondii F5/8 type C domain-containing protein 0.0053 0.003 0.0722
Toxoplasma gondii F5/8 type C domain-containing protein 0.0053 0.003 0.0722
Echinococcus granulosus discoidin domain containing receptor 2 0.0053 0.003 0.003
Schistosoma mansoni glutamate receptor AMPA 0.003 0.0005 0.0005
Entamoeba histolytica protein kinase, putative 0.0042 0.0018 0.0158
Trichomonas vaginalis WD repeat domain, putative 0.0278 0.0278 0.0446
Schistosoma mansoni glutamate receptor NMDA 0.0046 0.0022 0.0022

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) > 10 mg kg-1 Tested for the protection against glutamic acid-evoked convulsions in rats by intraperitoneal administration ChEMBL. 10425092

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.