Detailed information for compound 1574436

Basic information

Technical information
  • TDR Targets ID: 1574436
  • Name: N-(2-fluorophenyl)-2-(2-oxo-5-phenyl-3H-1,4-b enzodiazepin-1-yl)butanamide
  • MW: 415.459 | Formula: C25H22FN3O2
  • H donors: 1 H acceptors: 2 LogP: 4.53 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(N1C(=O)CN=C(c2c1cccc2)c1ccccc1)C(=O)Nc1ccccc1F
  • InChi: 1S/C25H22FN3O2/c1-2-21(25(31)28-20-14-8-7-13-19(20)26)29-22-15-9-6-12-18(22)24(27-16-23(29)30)17-10-4-3-5-11-17/h3-15,21H,2,16H2,1H3,(H,28,31)
  • InChiKey: KBIJOCKWKSBPRM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-fluorophenyl)-2-(2-keto-5-phenyl-3H-1,4-benzodiazepin-1-yl)butyramide
  • C386-0045
  • NCGC00108104-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0284 0.0292
Toxoplasma gondii protease inhibitor PI2 0.0039 0.0302 0.2236
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0602 0.1711
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0089 0.0089
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0016 0.0027 0.0025
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0066 0.0049
Schistosoma mansoni hypothetical protein 0.0016 0.0027 0.0025
Loa Loa (eye worm) doublecortin family protein 0.0083 0.0814 0.0851
Echinococcus granulosus nAChR subunit 0.0019 0.0069 0.0069
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0422 0.0436
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0112 0.1152 0.2062
Schistosoma mansoni ap endonuclease 0.0019 0.0068 0.0067
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0016 0.0027 0.0025
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0016 0.0027 0.0025
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0979 0.2814
Echinococcus granulosus RUN 0.0083 0.0814 0.0844
Schistosoma mansoni hypothetical protein 0.0019 0.0066 0.0065
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0272 0.2672
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0489 0.0503
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0016 0.0027 0.0025
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0085 0.0086
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0198 0.1797
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0112 0.1152 0.1136
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0356 0.0646
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0112 0.1152 0.1195
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0066 0.0065
Plasmodium vivax vivapain-2 0.0017 0.0043 0.0269
Trichomonas vaginalis proliferating cell nuclear antigen, putative 0.0097 0.097 0.1758
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0068 0.0145
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0314 0.0748
Onchocerca volvulus 0.0016 0.0029 0.0022
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0284 0.0292
Echinococcus granulosus Nuclear hormone receptor HR96 0.0053 0.0461 0.0476
Schistosoma mansoni hypothetical protein 0.0049 0.0417 0.0431
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0272 0.028
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0979 0.1774
Loa Loa (eye worm) hypothetical protein 0.0112 0.1152 0.1211
Echinococcus granulosus Ankyrin 0.0015 0.0019 0.0016
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0043 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.1295 0.4058
Brugia malayi nuclear hormone receptor 0.0112 0.1152 0.1136
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0059 0.0535 0.0553
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0068 0.0526
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0544 0.0528
Leishmania major cathepsin L-like protease 0.0017 0.0043 0.0073
Echinococcus granulosus ecdysone induced protein 78C 0.0112 0.1152 0.1195
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Plasmodium falciparum proliferating cell nuclear antigen 1 0.0097 0.097 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0198 0.0527
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0429 0.483 0.5139
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0029 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0085 0.0155
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0043 0.0042
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0085 0.0086
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.0979 0.1015
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0112 0.1152 0.1195
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0105 0.1065 0.1105
Echinococcus multilocularis dna polymerase eta 0.0015 0.0018 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0573 0.0592
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0112 0.1152 0.1136
Echinococcus granulosus geminin 0.0348 0.3892 0.4046
Trypanosoma cruzi MFS transporter, putative 0.0058 0.0514 0.1453
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0148 0.1559 0.4932
Loa Loa (eye worm) hypothetical protein 0.0058 0.0514 0.0531
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0029 0.0027
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0085 0.0086
Brugia malayi Protein kinase domain containing protein 0.0015 0.0021 0.0004
Onchocerca volvulus 0.0039 0.0302 0.0517
Echinococcus granulosus cathepsin l1 0.0017 0.0043 0.0042
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.3354 0.608
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0085 0.0073
Brugia malayi Nuclear hormone receptor-like 1 0.0821 0.9383 0.9382
Onchocerca volvulus 0.0055 0.0489 0.0857
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0284 0.0292
Onchocerca volvulus 0.0016 0.0029 0.0022
Schistosoma mansoni glutamate receptor AMPA 0.0016 0.0027 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Brugia malayi secreted modular calcium-binding protein 1 0.0039 0.0302 0.0285
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0085 0.0086
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0019 0.0069 0.0069
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0461 0.0476
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0112 0.1152 0.1195
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.3431 1
Schistosoma mansoni hypothetical protein 0.0083 0.0814 0.0844
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0085 0.0086
Brugia malayi nuclear receptor NHR-88 0.0053 0.0461 0.0445
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0085 0.0086
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0356 0.2663
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0105 0.1065 0.1105
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0112 0.1152 0.1211
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0039 0.0302 0.0285
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0043 0.0042
Brugia malayi orphan nuclear receptor NR2E1 0.0053 0.0461 0.0445
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0284 0.0514
Entamoeba histolytica cysteine protease, putative 0.0017 0.0043 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Echinococcus multilocularis lamin dm0 0.0055 0.0489 0.0505
Brugia malayi Doublecortin family protein 0.0083 0.0814 0.0798
Onchocerca volvulus 0.0037 0.0272 0.0463
Trypanosoma brucei polo-like protein kinase 0.0098 0.0979 0.2814
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0019 0.0069 0.0052
Echinococcus granulosus dna polymerase eta 0.0015 0.0018 0.0016
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0043 0.0042
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0039 0.0302 0.2236
Brugia malayi beta-lactamase family protein 0.0037 0.0272 0.0255
Schistosoma mansoni glutaminase 0.0279 0.3091 0.3213
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0043 0.0149
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0029 0.0012
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0073
Schistosoma mansoni nuclear receptor 0.0053 0.0461 0.0476
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0314 0.0885
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0016 0.0029 0.0027
Mycobacterium ulcerans beta-lactamase 0.0037 0.0272 0.0676
Loa Loa (eye worm) hypothetical protein 0.0058 0.0514 0.0531
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0112 0.1152 0.1195
Echinococcus multilocularis expressed protein 0.0039 0.0302 0.0311
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0734 0.0765
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0029 0.0012
Onchocerca volvulus 0.0053 0.0461 0.0807
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0112 0.1152 0.1195
Schistosoma mansoni netrin receptor unc5 0.0015 0.0017 0.0015
Echinococcus multilocularis glutamate receptor 2 0.0016 0.0027 0.0025
Loa Loa (eye worm) fibroinase 0.0017 0.0043 0.0028
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0037 0.0272 0.0272
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0019 0.0069 0.0069
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0016 0.0027 0.0025
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0043 0.0073
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0085 0.0828 0.0858
Onchocerca volvulus 0.0019 0.0069 0.0094
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0024 0.0121 0.0122
Leishmania major cathepsin L-like protease 0.0065 0.0602 0.1711
Schistosoma mansoni hypothetical protein 0.0085 0.0828 0.0858
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0019 0.0069 0.0069
Schistosoma mansoni apoptosis regulator bax 0.0085 0.0828 0.0858
Onchocerca volvulus 0.0037 0.0272 0.0463
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0734 0.076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0068 0.0145
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Echinococcus granulosus Solute carrier organic anion transporter family 0.0058 0.0514 0.0532
Schistosoma mansoni hypothetical protein 0.0015 0.0017 0.0015
Loa Loa (eye worm) steroid hormone receptor 0.0112 0.1152 0.1211
Giardia lamblia DINP protein human, muc B family 0.0022 0.0098 0.009
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0085 0.0086
Loa Loa (eye worm) proliferating cell nuclear antigen 0.0097 0.097 0.1017
Loa Loa (eye worm) hypothetical protein 0.0038 0.0284 0.0285
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Onchocerca volvulus 0.0019 0.0069 0.0094
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0053 0.0461 0.0476
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0979 0.1774
Loa Loa (eye worm) hypothetical protein 0.0458 0.5163 0.5494
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0272 0.0744
Onchocerca volvulus 0.0058 0.0514 0.0903
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0056 0.0495 0.0512
Trichomonas vaginalis glutaminase, putative 0.0279 0.3091 0.5603
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0024 0.0121 0.0122
Entamoeba histolytica hypothetical protein 0.0037 0.0272 0.076
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0085 0.0086
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0284 0.0514
Trypanosoma brucei unspecified product 0.0036 0.0258 0.0703
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0016 0.0027 0.0025
Brugia malayi TAR-binding protein 0.0076 0.0734 0.0718
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0085 0.0073
Mycobacterium ulcerans lipase LipD 0.0037 0.0272 0.0676
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.004 0.0312 0.0851
Echinococcus granulosus GPCR family 2 0.0019 0.0066 0.0065
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0198 0.1427
Treponema pallidum fructose-bisphosphate aldolase 0.0302 0.3354 1
Brugia malayi Nuclear hormone receptor-like 1 0.0821 0.9383 0.9382
Brugia malayi hypothetical protein 0.0037 0.0272 0.0255
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0573 0.0592
Echinococcus multilocularis proliferating cell nuclear antigen 0.0097 0.097 0.1006
Brugia malayi conserved hypotetical protein 0.0053 0.0461 0.0445
Echinococcus multilocularis nAChR subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.0979 0.2814
Schistosoma mansoni cpg binding protein 0.0062 0.057 0.0589
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0029 0.0107
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0284 0.0514
Schistosoma mansoni microtubule-associated protein tau 0.0705 0.804 0.8362
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0101 0.0084
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0112 0.1152 0.1211
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0544 0.0528
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0013
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0069 0.0069
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0734 0.0765
Giardia lamblia Fructose-bisphosphate aldolase 0.0302 0.3354 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Loa Loa (eye worm) glutamate receptor 2 0.0016 0.0027 0.0011
Loa Loa (eye worm) acetyltransferase 0.015 0.1585 0.1674
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0069 0.0055
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0302 0.3354 1
Onchocerca volvulus 0.0091 0.09 0.1605
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0043 0.0079
Brugia malayi Cathepsin L-like precursor 0.0017 0.0043 0.0026
Schistosoma mansoni terminal deoxycytidyl transferase 0.0015 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0304
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0044 0.0074
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0029 0.0122
Loa Loa (eye worm) serotonin transporter b 0.0016 0.0029 0.0013
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0029 0.0012
Loa Loa (eye worm) DR-78 0.0053 0.0461 0.0474
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0016 0.0029 0.0027
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0043 0.0073
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0043 0.0026
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0017 0.0015
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0041 0.0039
Echinococcus granulosus FTZ F1 alpha 0.0112 0.1152 0.1195
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.1215 0.1261
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0085 0.0828 0.0858
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0069 0.0052
Onchocerca volvulus 0.0019 0.0069 0.0094
Loa Loa (eye worm) hypothetical protein 0.0063 0.0573 0.0593
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0461 0.0476
Onchocerca volvulus 0.0017 0.0043 0.0048
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.004 0.0312 0.1149
Trypanosoma cruzi proliferative cell nuclear antigen (PCNA), putative 0.0097 0.097 0.2788
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0979 0.1015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Brugia malayi Glutamate receptor 2 precursor 0.0016 0.0027 0.001
Echinococcus granulosus glutamate receptor subunit protein glur 0.0016 0.0027 0.0025
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0091 0.09 0.0934
Loa Loa (eye worm) glutaminase 0.0279 0.3091 0.3282
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0019 0.0069 0.0069
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0043 0.0075
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0272 0.0493
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0019 0.0069 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Echinococcus granulosus lamin 0.0055 0.0489 0.0505
Brugia malayi Glutamate receptor 1 precursor 0.0016 0.0027 0.001
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0338 0.0936
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0085 0.0086
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0573 0.0592
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0019 0.0069 0.0052
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0272 0.0272
Trypanosoma brucei DNA polymerase IV, putative 0.0036 0.0258 0.0703
Echinococcus granulosus single minded 2 0.0037 0.0272 0.028
Echinococcus granulosus dna polymerase kappa 0.0042 0.0338 0.0348
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0112 0.1152 0.1136
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0112 0.1152 0.1195
Loa Loa (eye worm) solute carrier family 6 member 4 0.0016 0.0029 0.0013
Loa Loa (eye worm) glutamate receptor 1 0.0016 0.0027 0.0011
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.053 0.0548
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0069 0.0069
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0069 0.0069
Brugia malayi prostaglandin transporter 0.0058 0.0514 0.0498
Schistosoma mansoni hypothetical protein 0.0085 0.0828 0.0858
Echinococcus granulosus intermediate filament protein 0.0055 0.0489 0.0505
Brugia malayi photoreceptor-specific nuclear receptor 0.0112 0.1152 0.1136
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0272 0.0676
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0112 0.1152 0.1136
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0019 0.0069 0.0052
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0105 0.1065 0.1105
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0734 0.076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0043 0.0079
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0091 0.09 0.0943
Echinococcus multilocularis lipoxygenase domain containing protein 0.0083 0.0814 0.0844
Brugia malayi nuclear receptor RXR 0.0053 0.0461 0.0445
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0112 0.1152 0.1136
Loa Loa (eye worm) hypothetical protein 0.0059 0.0535 0.0553
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.0979 0.0963
Brugia malayi Cation transporter family protein 0.0019 0.0069 0.0052
Leishmania major cathepsin L-like protease 0.0065 0.0602 0.1711
Schistosoma mansoni loxhd1 0.0083 0.0814 0.0844
Schistosoma mansoni glutamate receptor NMDA 0.0024 0.0121 0.0122
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0069 0.0055
Plasmodium falciparum LCCL domain-containing protein 0.0083 0.0814 0.8347
Schistosoma mansoni hypothetical protein 0.0019 0.0066 0.0065
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0053 0.0461 0.0807
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Loa Loa (eye worm) LGC-31 protein 0.0019 0.0069 0.0055
Schistosoma mansoni lipoxygenase 0.037 0.4147 0.4312
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0417 0.0401
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0024 0.0121 0.0122
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0015 0.0018 0.0016
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0068 0.0145
Schistosoma mansoni hypothetical protein 0.0019 0.0066 0.0065
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0024 0.0121 0.0122
Onchocerca volvulus 0.0016 0.0029 0.0022
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0089 0.0077
Schistosoma mansoni ap endonuclease 0.0019 0.0068 0.0067
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Brugia malayi hypothetical protein 0.0458 0.5163 0.5155
Chlamydia trachomatis glutamine binding protein 0.004 0.0312 1
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0085 0.0086
Schistosoma mansoni nuclear receptor 0.0053 0.0461 0.0476
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0218 0.0584
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.1295 0.4058
Toxoplasma gondii hypothetical protein 0.0016 0.0029 0.0107
Echinococcus multilocularis dna polymerase kappa 0.0042 0.0338 0.0348
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0019 0.0069 0.0069
Echinococcus multilocularis dnaJ subfamily B 0.0841 0.9613 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0535 0.0553
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0019 0.0016
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0284 0.0292
Schistosoma mansoni nuclear hormone receptor 0.0053 0.0461 0.0476
Echinococcus granulosus sodium and chloride dependent glycine 0.0016 0.0029 0.0027
Onchocerca volvulus 0.0019 0.0069 0.0094
Onchocerca volvulus 0.0017 0.0043 0.0048
Loa Loa (eye worm) ctsf protein 0.0017 0.0043 0.0028
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.1542 0.4464
Echinococcus granulosus tar DNA binding protein 0.0076 0.0734 0.076
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.1542 0.4464
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Mycobacterium tuberculosis Conserved protein 0.0037 0.0272 0.0992
Leishmania major cathepsin L-like protease 0.0017 0.0043 0.0073
Toxoplasma gondii proliferating cell nuclear antigen PCNA2 0.0052 0.0446 0.3367
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0068 0.0116
Brugia malayi polk-prov protein 0.0032 0.0218 0.0201
Schistosoma mansoni nuclear hormone receptor 0.0112 0.1152 0.1195
Echinococcus granulosus Nuclear hormone receptor HR96 0.0053 0.0461 0.0476
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Echinococcus multilocularis cysteine protease 0.0017 0.0043 0.0042
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0085 0.0086
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0118 0.1215 0.4677
Brugia malayi Cathepsin L-like precursor 0.0017 0.0043 0.0026
Echinococcus multilocularis lamin 0.0055 0.0489 0.0505
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.1326 0.1376
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.0979 0.1015
Brugia malayi Pre-SET motif family protein 0.0063 0.0573 0.0556
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.1295 0.1344
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.004 0.0312 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.09 0.0943
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0066 0.0049
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0039 0.0302 0.2236
Onchocerca volvulus 0.0017 0.0043 0.0048
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.2653 0.2757
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0041 0.0039
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0272 0.0992
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0013
Schistosoma mansoni glutamate receptor NMDA 0.0016 0.0027 0.0025
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0066 0.0065
Schistosoma mansoni proliferating cell nuclear antigen 0.0097 0.097 0.1006
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.044 0.1236
Loa Loa (eye worm) cysteine protease 0.0017 0.0043 0.0028
Echinococcus granulosus thyroid hormone receptor alpha 0.0053 0.0461 0.0476
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.1295 0.1344
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0338 0.0892
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.1213 0.936
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0098 0.0232
Loa Loa (eye worm) hypothetical protein 0.0112 0.1152 0.1211
Echinococcus multilocularis ecdysone induced protein 78C 0.0112 0.1152 0.1195
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0053 0.0461 0.0807
Loa Loa (eye worm) hypothetical protein 0.0814 0.931 0.9921
Onchocerca volvulus 0.0016 0.0029 0.0022
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.1585 0.157
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.1542 0.4464
Brugia malayi sodium-independent organic anion transporter family protein 0.0058 0.0514 0.0498
Schistosoma mansoni sodium-dependent amino acid transporter 0.0016 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.0112 0.1152 0.1211
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0272 0.0493
Brugia malayi sodium-independent organic anion transporter family protein 0.0091 0.09 0.0885
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0041 0.0039
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0066 0.0065
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.3354 0.608
Onchocerca volvulus 0.0083 0.0814 0.1449
Plasmodium vivax proliferating cell nuclear antigen, putative 0.0097 0.097 1
Plasmodium vivax amine transporter, putative 0.0016 0.0029 0.0122
Onchocerca volvulus 0.0458 0.5163 0.9354
Brugia malayi hypothetical protein 0.0021 0.0085 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Onchocerca volvulus 0.0055 0.0489 0.0857
Brugia malayi hypothetical protein 0.0083 0.0814 0.0798
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0349 0.0968
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0043 0.0079
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0244 0.2683 0.2846
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0304
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0979 0.1774
Loa Loa (eye worm) hypothetical protein 0.0112 0.1152 0.1211
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0112 0.1152 0.1136
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0016 0.0029 0.0027
Onchocerca volvulus Putative organic anion transporter 0.0058 0.0514 0.0903
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0338 0.0936
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0085 0.0155
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0016 0.0027 0.0025
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.1295 1
Schistosoma mansoni agrin 0.0039 0.0302 0.0311
Onchocerca volvulus 0.0063 0.0573 0.1009
Echinococcus multilocularis nmda type glutamate receptor 0.0056 0.0495 0.0512
Loa Loa (eye worm) hypothetical protein 0.0058 0.0514 0.0531
Echinococcus multilocularis geminin 0.0348 0.3892 0.4046
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0073
Brugia malayi ecdysone receptor 0.0053 0.0461 0.0445
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.006 0.0544 0.0563
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.004 0.0312 0.0809
Loa Loa (eye worm) hypothetical protein 0.0032 0.0218 0.0214
Loa Loa (eye worm) hypothetical protein 0.0037 0.0272 0.0272
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0043 0.0075
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0105 0.1065 0.1105
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0043 0.0042
Schistosoma mansoni lozenge 0.0057 0.0512 0.0529
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0272 0.028
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0284 0.0778
Loa Loa (eye worm) hypothetical protein 0.0083 0.0814 0.0851
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Brugia malayi excitatory GABA receptor EXP-1A 0.0019 0.0069 0.0052
Entamoeba histolytica hypothetical protein 0.0021 0.0085 0.0201
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0018 0.0001
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.1295 0.499
Echinococcus multilocularis sodium and chloride dependent glycine 0.0016 0.0029 0.0027
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0059 0.0535 0.0553
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0085 0.0086
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0272 0.0992
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0016 0.0029 0.0013
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0043 0.0028
Plasmodium vivax multidomain scavenger receptor, putative 0.0083 0.0814 0.8367
Leishmania major hypothetical protein, conserved 0.003 0.0198 0.0527
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0043 0.0079
Loa Loa (eye worm) hypothetical protein 0.0167 0.1783 0.1885
Entamoeba histolytica hypothetical protein 0.0037 0.0272 0.076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Onchocerca volvulus 0.0017 0.0043 0.0048
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0532 0.6028 0.6269
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.0029 0.0027
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0024 0.0121 0.0122
Schistosoma mansoni thyroid hormone receptor 0.0645 0.7335 0.7629
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0284 0.0292
Loa Loa (eye worm) hypothetical protein 0.0058 0.0514 0.0531
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0013
Plasmodium falciparum proliferating cell nuclear antigen 2 0.0052 0.0446 0.4435
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0085 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0043 0.0079
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0019 0.0069 0.0069
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.008 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0406 0.0736
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.0029 0.0027
Schistosoma mansoni ATP-binding cassette transporter 0.0016 0.0027 0.0025
Schistosoma mansoni intermediate filament proteins 0.0055 0.0489 0.0505
Schistosoma mansoni lipoxygenase 0.022 0.2401 0.2495
Brugia malayi nuclear receptor NHR-67 0.0053 0.0461 0.0445
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0015 0.0018 0.0016
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0016 0.0029 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.3354 0.608
Echinococcus granulosus bloom syndrome protein 0.0022 0.0101 0.0102
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0304
Schistosoma mansoni glutamate receptor kainate 0.0016 0.0027 0.0025
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0069 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0085 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0112 0.1152 0.1136
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0085 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0112 0.1152 0.1136
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Trichomonas vaginalis set domain proteins, putative 0.0488 0.5517 1
Onchocerca volvulus 0.0058 0.0514 0.0903
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0101 0.0183
Echinococcus multilocularis musashi 0.0055 0.0489 0.0505
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.2576 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.3354 0.608
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0101 0.0183
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0017 0.0015
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.0338 0.0612
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0043 0.0079
Brugia malayi proliferating cell nuclear antigen (PCNA) 0.0097 0.097 0.0954
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.1295 0.1344
Schistosoma mansoni lamin 0.0055 0.0489 0.0505
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0356 0.0646
Schistosoma mansoni nuclear receptor nhr-48 0.0053 0.0461 0.0476
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0284 0.0292
Echinococcus multilocularis nuclear receptor nhr 48 0.0053 0.0461 0.0476
Echinococcus multilocularis neuropeptide receptor A26 0.0482 0.5445 0.5662
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0085 0.0086
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0019 0.0069 0.0055
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0069 0.0069
Echinococcus granulosus nuclear receptor nhr 48 0.0053 0.0461 0.0476
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0085 0.0086
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0284 0.0267
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0085 0.0073
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0272 0.0676
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0066 0.0052
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0019 0.0069 0.0055
Echinococcus multilocularis GPCR, family 2 0.0019 0.0066 0.0065
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0043 0.0149
Brugia malayi hypothetical protein 0.0053 0.0461 0.0445
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0052
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0272 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0085 0.0155
Onchocerca volvulus 0.0019 0.0069 0.0094
Loa Loa (eye worm) hypothetical protein 0.0242 0.2653 0.2814
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0068 0.5
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Schistosoma mansoni kinase 0.005 0.0421 0.0435
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0573 0.0592
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0039 0.0302 0.0304
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0043 0.0048
Echinococcus granulosus cpg binding protein 0.0062 0.057 0.0589
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0039 0.0302 0.0285
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0356 0.2663
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0068 0.0067
Echinococcus granulosus neuropeptide s receptor 0.0482 0.5445 0.5662
Loa Loa (eye worm) hypothetical protein 0.0041 0.0323 0.0326
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0406 0.0736
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0019 0.0069 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0073
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0068 0.0145
Schistosoma mansoni retinoic acid receptor RXR 0.0112 0.1152 0.1195
Toxoplasma gondii ABC1 family protein 0.0037 0.0272 0.2004
Brugia malayi hypothetical protein 0.0053 0.0461 0.0445
Echinococcus granulosus neuropeptide receptor A26 0.0482 0.5445 0.5662
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0198 0.1896
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0085 0.0086
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0029 0.0027
Onchocerca volvulus 0.0083 0.0814 0.1449
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0015 0.0018 0.0016
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0069 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0218 0.0584
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0356 0.3557
Echinococcus multilocularis cysteine protease 0.0017 0.0043 0.0042
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0053 0.0461 0.0476
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0272 0.0676
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0544 0.0563
Brugia malayi tailless protein 0.0053 0.0461 0.0445
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0017 0.0015
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0091 0.09 0.0934
Brugia malayi Cation transporter family protein 0.0019 0.0069 0.0052
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0029 0.0107
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Onchocerca volvulus 0.0091 0.09 0.1605
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0043 0.0079
Schistosoma mansoni hypothetical protein 0.0053 0.0466 0.0481
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0085 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0979 0.1774
Mycobacterium ulcerans hypothetical protein 0.0037 0.0272 0.0676
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0356 0.0367
Brugia malayi PAS domain containing protein 0.005 0.0422 0.0406
Echinococcus granulosus lamin dm0 0.0055 0.0489 0.0505
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0105 0.1065 0.1105
Brugia malayi hypothetical protein 0.0167 0.1783 0.1769
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0112 0.1152 0.1195
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0043 0.0079
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0734 0.076
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0044 0.0074
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0052
Echinococcus granulosus expressed protein 0.0404 0.4535 0.4716
Loa Loa (eye worm) norepinephrine transporter 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.0058 0.0514 0.0531
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0272 0.0493
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0089 0.0072
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0112 0.1152 0.1195
Schistosoma mansoni steroid hormone receptor ad4bp 0.0112 0.1152 0.1195
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.037 0.4147 0.4312
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0085 0.0828 0.0858
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0112 0.1152 0.1136
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0729 0.0755
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0018 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0155 0.0148
Echinococcus multilocularis expressed protein 0.0404 0.4535 0.4716
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0053 0.0461 0.0445
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0085 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Onchocerca volvulus 0.0017 0.0043 0.0048
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0349 0.0968
Entamoeba histolytica hypothetical protein 0.0021 0.0085 0.0201
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0198 0.0527
Schistosoma mansoni follistatin 0.0039 0.0302 0.0311
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0272 0.0279
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.1215 0.3793
Loa Loa (eye worm) hypothetical protein 0.0059 0.0535 0.0553
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0052
Echinococcus granulosus lipoxygenase domain containing protein 0.0083 0.0814 0.0844
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0323 0.0306
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0489 0.0503
Schistosoma mansoni hypothetical protein 0.0348 0.3892 0.4046
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0112 0.1152 0.1195
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0019 0.0069 0.0055
Loa Loa (eye worm) hypothetical protein 0.0083 0.0814 0.0851
Onchocerca volvulus Protein ultraspiracle homolog 0.0112 0.1152 0.2062
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0085 0.0086
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.007 0.0428
Leishmania major DNA polymerase kappa, putative 0.0022 0.0098 0.0232
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Entamoeba histolytica hypothetical protein 0.0037 0.0272 0.076
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0112 0.1152 0.1195
Loa Loa (eye worm) agrin synaptic family protein 0.0039 0.0302 0.0304
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0112 0.1152 0.1211
Brugia malayi Cathepsin L-like precursor 0.0017 0.0043 0.0026
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0198 0.1797
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0089 0.0089
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0068 0.0149
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0085 0.0068
Onchocerca volvulus 0.0059 0.053 0.0933
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Schistosoma mansoni hypothetical protein 0.0041 0.0323 0.0333
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Echinococcus multilocularis neuropeptide s receptor 0.0482 0.5445 0.5662
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0284 0.0657
Brugia malayi nuclear hormone receptor family member nhr-6 0.0053 0.0461 0.0445
Brugia malayi follicle stimulating hormone receptor 0.0244 0.2683 0.267
Loa Loa (eye worm) nuclear hormone receptor 0.0053 0.0461 0.0474
Entamoeba histolytica hypothetical protein 0.0021 0.0085 0.0201
Echinococcus granulosus microtubule associated protein 2 0.0705 0.804 0.8362
Schistosoma mansoni rab6-interacting 0.0083 0.0814 0.0844
Brugia malayi Cation transporter family protein 0.0019 0.0069 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.3354 0.608
Echinococcus multilocularis Protein lozenge 0.0057 0.0512 0.0529
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0068 0.0194
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0041 0.0039
Leishmania major cathepsin L-like protease 0.0017 0.0043 0.0073
Loa Loa (eye worm) beta-lactamase 0.0037 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0073
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0284 0.0778
Onchocerca volvulus Putative organic anion transporter 0.0058 0.0514 0.0903
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0085 0.0086
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0112 0.1152 0.1195
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0201 0.0196
Brugia malayi CXXC zinc finger family protein 0.0059 0.053 0.0514
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0459 0.1292
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0085 0.0828 0.0858
Loa Loa (eye worm) runx1 0.0057 0.0512 0.0528
Brugia malayi Cathepsin L-like precursor 0.0017 0.0043 0.0026
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0101 0.0102
Brugia malayi hypothetical protein 0.0058 0.0514 0.0498
Onchocerca volvulus Putative nachr subunit 0.0019 0.0069 0.0094
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0016 0.0029 0.0027
Echinococcus multilocularis cpg binding protein 0.0062 0.057 0.0589
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0118 0.1215 0.1261
Echinococcus granulosus death domain containing protein 0.0015 0.0017 0.0015
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0083 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Brugia malayi Steroid receptor seven-up type 2 0.0112 0.1152 0.1136
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.3354 0.608
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0043 0.0079
Brugia malayi nuclear receptor NHR-88 0.0112 0.1152 0.1136
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0284 0.0292
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Brugia malayi hypothetical protein 0.0059 0.0535 0.0519
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0073
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0112 0.1152 0.1211
Onchocerca volvulus 0.0037 0.0272 0.0463
Schistosoma mansoni DNA polymerase eta 0.0015 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0037 0.0272 0.0272
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0979 0.1774
Loa Loa (eye worm) hypothetical protein 0.0026 0.0144 0.0135
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0979 0.1774
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0043 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Onchocerca volvulus 0.0037 0.0272 0.0463
Echinococcus granulosus arachidonate 5 lipoxygenase 0.037 0.4147 0.4312
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Echinococcus multilocularis FTZ F1 alpha 0.0112 0.1152 0.1195
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0734 0.076
Onchocerca volvulus 0.0058 0.0514 0.0903
Brugia malayi glutaminase DH11.1 0.0279 0.3091 0.3079
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0272 0.0255
Echinococcus multilocularis serotonin transporter 0.0016 0.0029 0.0027
Brugia malayi ecdysteroid receptor 0.0112 0.1152 0.1136
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0083 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0085 0.0155
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0573 0.4353
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Trichomonas vaginalis esterase, putative 0.0037 0.0272 0.0493
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0272 0.0744
Mycobacterium ulcerans glutaminase 0.0279 0.3091 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0029 0.0027
Plasmodium vivax vivapain-2 0.0017 0.0043 0.0269
Schistosoma mansoni RAR-like nuclear receptor 0.0112 0.1152 0.1195
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0112 0.1152 0.1211
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.0979 0.1027
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0039 0.0302 0.2236
Toxoplasma gondii exonuclease III APE 0.0019 0.0068 0.0408
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0069 0.0069
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0112 0.1152 0.1195
Loa Loa (eye worm) hypothetical protein 0.0058 0.0514 0.0531
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.1295 0.4058
Loa Loa (eye worm) hypothetical protein 0.0059 0.0535 0.0553
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0112 0.1152 0.1211
Echinococcus granulosus agrin 0.0039 0.0302 0.0311
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0734 0.076
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0016 0.0029 0.0012
Brugia malayi PXA domain containing protein 0.0021 0.0085 0.0068
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0016 0.0029 0.0013
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0118 0.1215 0.12
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0013
Brugia malayi intermediate filament protein 0.0055 0.0489 0.0472
Schistosoma mansoni polycystin 1-related 0.0083 0.0814 0.0844
Schistosoma mansoni hypothetical protein 0.0085 0.0828 0.0858
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0284 0.0796
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0068 0.0054
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Loa Loa (eye worm) glutaminase 2 0.0279 0.3091 0.3282
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0085 0.0086
Brugia malayi Cathepsin L-like precursor 0.0017 0.0043 0.0026
Echinococcus granulosus lipoxygenase domain containing protein 0.0083 0.0814 0.0844
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0272 0.0992
Echinococcus granulosus nmda type glutamate receptor 0.0056 0.0495 0.0512
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0054 0.0477 0.0491
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0272 0.0279
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0024 0.0121 0.0122
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0059 0.0535 0.0553
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0019 0.0069 0.0052
Brugia malayi Uncoordinated protein 44 0.0015 0.0017 0.000000039941
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0112 0.1152 0.1195
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0085 0.0086
Brugia malayi beta-lactamase 0.0037 0.0272 0.0255
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0043 0.0149
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0013
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0309 0.3431 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0531 0.0549
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0085 0.0068
Leishmania major cathepsin L-like protease 0.0017 0.0043 0.0073
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0602 0.1711
Onchocerca volvulus 0.0049 0.0417 0.0727
Echinococcus multilocularis thyroid hormone receptor alpha 0.0645 0.7335 0.7629
Brugia malayi PXA domain containing protein 0.0021 0.0085 0.0068
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0729 0.0755
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0112 0.1152 0.1211
Echinococcus multilocularis Polycystic kidney disease protein 0.0083 0.0814 0.0844
Entamoeba histolytica proliferating cell nuclear antigen, putative 0.0097 0.097 0.2852
Brugia malayi nuclear hormone receptor family member odr-7 0.0053 0.0461 0.0445
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0039 0.0302 0.0285
Loa Loa (eye worm) hypothetical protein 0.0458 0.5163 0.5494
Loa Loa (eye worm) RecQ helicase 0.0022 0.0101 0.0089
Schistosoma mansoni coup transcription factor 0.0112 0.1152 0.1195
Brugia malayi hypoxia-induced factor 1 0.0154 0.1633 0.1618
Brugia malayi Nuclear hormone receptor E75 0.0053 0.0461 0.0445
Toxoplasma gondii hypothetical protein 0.005 0.0423 0.3184
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0013
Echinococcus granulosus serotonin transporter 0.0016 0.0029 0.0027
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0272 0.0992
Brugia malayi hypothetical protein 0.0021 0.0085 0.0068
Brugia malayi Death domain containing protein 0.0015 0.0017 0.000000039941
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Schistosoma mansoni hypothetical protein 0.0348 0.3892 0.4046
Loa Loa (eye worm) hypothetical protein 0.0105 0.1065 0.1119
Brugia malayi Pre-SET motif family protein 0.0429 0.483 0.4821
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0338 0.0892
Schistosoma mansoni hypothetical protein 0.0841 0.9613 1
Trypanosoma brucei proliferative cell nuclear antigen (PCNA), putative 0.0097 0.097 0.2788
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0272 0.0744
Brugia malayi hypothetical protein 0.0083 0.0814 0.0798
Schistosoma mansoni zinc finger protein 0.0053 0.0461 0.0476
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0272 0.0493
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0068 0.0051
Echinococcus multilocularis sodium and chloride dependent glycine 0.0016 0.0029 0.0027
Brugia malayi hypothetical protein 0.0059 0.0535 0.0519
Schistosoma mansoni rab6-interacting 0.0083 0.0814 0.0844
Toxoplasma gondii hypothetical protein 0.0016 0.0029 0.0107
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.006 0.0536 0.1518
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0085 0.0086
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0112 0.1152 0.1195
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0089 0.0077
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0602 0.1711
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0047 0.0045
Brugia malayi hypothetical protein 0.0016 0.0029 0.0012
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0069 0.0069
Toxoplasma gondii transporter, major facilitator family protein 0.0058 0.0514 0.3897
Loa Loa (eye worm) hypothetical protein 0.0026 0.0144 0.0135
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0112 0.1152 0.1136
Brugia malayi steroid hormone receptor 0.0112 0.1152 0.1136
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0602 0.1711
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0024 0.0121 0.0122
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0112 0.1152 0.1195
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0118 0.1215 0.3505
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0044 0.0074
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0053 0.0461 0.0476
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0085 0.0086
Schistosoma mansoni hypothetical protein 0.0532 0.6028 0.6269
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.0979 0.2879
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0979 0.1774
Loa Loa (eye worm) hypoxia-induced factor 1 0.0154 0.1633 0.1725
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0821 0.9383 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.3354 0.608
Loa Loa (eye worm) hypothetical protein 0.0112 0.1152 0.1211
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.0338 0.0612
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.1585 0.1646
Mycobacterium ulcerans hypothetical protein 0.0112 0.1148 0.3574
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0089 0.0089
Schistosoma mansoni thyroid hormone receptor 0.0645 0.7335 0.7629
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0068 0.0123
Loa Loa (eye worm) hypothetical protein 0.0017 0.0043 0.0028
Schistosoma mansoni survival motor neuron protein 0.0049 0.0417 0.0431
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Onchocerca volvulus 0.0112 0.1152 0.2062
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0314 0.3024
Onchocerca volvulus Bile acid receptor homolog 0.0112 0.1152 0.2062
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.004 0.0312 0.0851
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0029 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Loa Loa (eye worm) hypothetical protein 0.0105 0.1065 0.1119
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0017 0.0015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0112 0.1152 0.1195
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0085 0.0155
Brugia malayi hypothetical protein 0.0242 0.2653 0.264
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Schistosoma mansoni organic anion transporter 0.0091 0.09 0.0934
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0272 0.0992
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0304
Echinococcus multilocularis lipoxygenase domain containing protein 0.0083 0.0814 0.0844
Loa Loa (eye worm) hypothetical protein 0.0037 0.0272 0.0272
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0015 0.0018 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0489 0.0472
Loa Loa (eye worm) hypothetical protein 0.0059 0.0535 0.0553
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.019 0.0173
Brugia malayi nuclear receptor RXR 0.0059 0.0535 0.0519
Echinococcus granulosus sodium and chloride dependent glycine 0.0016 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0069 0.0069
Trichomonas vaginalis proliferating cell nuclear antigen, putative 0.0097 0.097 0.1758
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.1295 0.1344
Schistosoma mansoni cpg binding protein 0.0062 0.057 0.0589
Loa Loa (eye worm) hypothetical protein 0.0085 0.0828 0.0866
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0198 0.0527
Echinococcus granulosus histone acetyltransferase KAT2B 0.0146 0.1536 0.1595
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0019 0.0069 0.0052
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0069 0.0069
Echinococcus multilocularis RUN 0.0083 0.0814 0.0844
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0043 0.0079
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0734 0.0718
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.2653 0.2757
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0019 0.0069 0.0069
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0302 0.3354 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0112 0.1152 0.1211
Schistosoma mansoni glutamate receptor kainate 0.0016 0.0027 0.0025
Brugia malayi hypothetical protein 0.003 0.0198 0.0181
Toxoplasma gondii cathepsin CPL 0.0017 0.0043 0.0216
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Schistosoma mansoni cpg binding protein 0.0059 0.053 0.0549
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0039 0.0302 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0089 0.0089
Brugia malayi Nuclear hormone receptor E75 0.0053 0.0461 0.0445
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.1585 0.1646
Loa Loa (eye worm) RNA binding protein 0.0076 0.0734 0.0765
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.0055 0.0489 0.0503
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0532 0.6028 0.6269
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0349 0.0968
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0112 0.1152 0.1195
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0155 0.0158
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0024 0.0121 0.0122
Toxoplasma gondii proliferating cell nuclear antigen PCNA1 0.0097 0.097 0.7459
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.3354 0.608
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0734 0.076
Loa Loa (eye worm) hypothetical protein 0.003 0.0198 0.0193
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.019 0.0184
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0017 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Brugia malayi nuclear hormone receptor 0.0053 0.0461 0.0445
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0272 0.028
Echinococcus granulosus proliferating cell nuclear antigen 0.0097 0.097 0.1006
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0979 0.2814
Mycobacterium tuberculosis Conserved protein 0.0037 0.0272 0.0992
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0284 0.0292
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0155 0.0158
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0068 0.0067
Brugia malayi Cathepsin L-like precursor 0.0017 0.0043 0.0026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0272 0.028
Schistosoma mansoni glutamate receptor AMPA 0.0016 0.0027 0.0025
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0112 0.1152 0.1136
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0043 0.0048
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0349 0.0968
Schistosoma mansoni organic anion transporter 0.0058 0.0514 0.0532
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0085 0.0086
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0085 0.0068
Schistosoma mansoni proliferating cell nuclear antigen 0.0097 0.097 0.1006
Entamoeba histolytica hypothetical protein 0.0037 0.0272 0.076
Onchocerca volvulus 0.0017 0.0043 0.0048
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0272 0.0992
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0019 0.0069 0.0052
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0573 0.0592
Onchocerca volvulus 0.0017 0.0043 0.0048
Brugia malayi hypothetical protein 0.0058 0.0514 0.0498
Echinococcus multilocularis agrin 0.0039 0.0302 0.0311
Mycobacterium ulcerans hypothetical protein 0.0163 0.1734 0.5511
Brugia malayi SPARC precursor 0.0039 0.0302 0.0285
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0272 0.0255
Leishmania major cathepsin L-like protease 0.0017 0.0043 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0112 0.1152 0.1136
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0059 0.0535 0.0553
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0029 0.0027
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0019 0.0069 0.0069
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0338 0.0936
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0085 0.0828 0.0812
Leishmania major mitochondrial DNA polymerase beta 0.0309 0.3431 1
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0085 0.0155
Brugia malayi beta-lactamase family protein 0.0037 0.0272 0.0255
Brugia malayi RNA binding protein 0.0076 0.0734 0.0718
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0058 0.0514 0.0532
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0069 0.0052
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0573 0.0592
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Echinococcus granulosus glutamate receptor 2 0.0024 0.0121 0.0122
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0098 0.0232
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0053 0.0461 0.0476
Echinococcus granulosus Polycystic kidney disease protein 0.0083 0.0814 0.0844
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.0034
Loa Loa (eye worm) apoptosis regulator protein 0.0085 0.0828 0.0866
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0019 0.0069 0.0055
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0085 0.0068
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0039 0.0302 0.2236
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0474
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.1215 0.1261
Echinococcus multilocularis Ankyrin 0.0015 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0112 0.1152 0.1211
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0053 0.0461 0.0476
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.3431 1
Echinococcus multilocularis glutamate receptor 2 0.0024 0.0121 0.0122
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0013
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0112 0.1152 0.1195
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0068 0.041
Echinococcus multilocularis NMDA receptor 0.0016 0.0027 0.0025
Brugia malayi hypothetical protein 0.002 0.0073 0.0056
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0043 0.0042
Schistosoma mansoni single-minded 0.005 0.0422 0.0436
Loa Loa (eye worm) hypothetical protein 0.0112 0.1152 0.1211
Onchocerca volvulus 0.0488 0.5518 1
Trypanosoma cruzi proliferative cell nuclear antigen (PCNA), putative 0.0097 0.097 0.2788
Onchocerca volvulus 0.0053 0.0461 0.0807
Onchocerca volvulus 0.0019 0.0069 0.0094
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0085 0.0068
Leishmania major cathepsin L-like protease 0.0065 0.0602 0.1711
Giardia lamblia Kinase, PLK 0.0098 0.0979 0.2772
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0098 0.031
Leishmania major proliferative cell nuclear antigen (PCNA), putative 0.0097 0.097 0.2788
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0053 0.0461 0.0476
Schistosoma mansoni hypothetical protein 0.0019 0.0066 0.0065
Echinococcus multilocularis microtubule associated protein 2 0.0705 0.804 0.8362
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0272 0.0992
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0019 0.0069 0.0055
Schistosoma mansoni hypothetical protein 0.0037 0.0272 0.0279
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0069 0.0069
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.011 0.1122 0.118
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0112 0.1152 0.1195
Plasmodium vivax proliferating cell nuclear antigen, putative 0.0052 0.0446 0.4502
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Echinococcus granulosus follistatin 0.0039 0.0302 0.0311
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0148 0.1559 0.6023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0602 0.1711
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0053 0.0461 0.0476
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0052
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.1295 0.374
Brugia malayi Cytochrome P450 family protein 0.0031 0.0201 0.0184
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.1215 0.3793
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0272 0.028
Giardia lamblia PcnA 0.0097 0.097 0.2744
Loa Loa (eye worm) hypothetical protein 0.0037 0.0272 0.0272
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0041 0.0039
Brugia malayi sodium-independent organic anion transporter family protein 0.0091 0.09 0.0885
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0043 0.0079
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0043 0.0048
Schistosoma mansoni lamin 0.0055 0.0489 0.0505
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0148 0.1559 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0055
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0272 0.0493
Echinococcus granulosus dnaJ subfamily B 0.0841 0.9613 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0284 0.0778
Mycobacterium tuberculosis Conserved protein 0.0037 0.0272 0.0992
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0085 0.0086
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0053 0.0461 0.0474
Schistosoma mansoni glutamate receptor kainate 0.0016 0.0027 0.0025
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.1734 0.6706
Loa Loa (eye worm) nuclear receptor NHR-67 0.0053 0.0461 0.0474
Plasmodium vivax SET domain protein, putative 0.0063 0.0573 0.5827
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0112 0.1152 0.1136
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0089 0.0089
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0029 0.0027
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0284 0.0778
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0068 0.0123
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.0979 0.1748
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0085 0.0828 0.0858
Schistosoma mansoni nuclear hormone receptor 0.0053 0.0461 0.0476
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0573 0.0592
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0069 0.0052
Leishmania major hypothetical protein, conserved 0.0037 0.0272 0.0744
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0085 0.0086
Onchocerca volvulus Putative organic anion transporter 0.0058 0.0514 0.0903
Echinococcus multilocularis follistatin 0.0039 0.0302 0.0311
Echinococcus granulosus glutamate NMDA receptor subunit 0.0016 0.0027 0.0025

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.3162 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.6234 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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