Detailed information for compound 1574965

Basic information

Technical information
  • TDR Targets ID: 1574965
  • Name: N-[2-[(4-methoxyphenyl)methyl-[2-oxo-2-(oxola n-2-ylmethylamino)-1-phenylethyl]amino]-2-oxo ethyl]furan-2-carboxamide
  • MW: 505.562 | Formula: C28H31N3O6
  • H donors: 2 H acceptors: 3 LogP: 3.04 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccc(cc1)CN(C(c1ccccc1)C(=O)NCC1CCCO1)C(=O)CNC(=O)c1ccco1
  • InChi: 1S/C28H31N3O6/c1-35-22-13-11-20(12-14-22)19-31(25(32)18-30-27(33)24-10-6-16-37-24)26(21-7-3-2-4-8-21)28(34)29-17-23-9-5-15-36-23/h2-4,6-8,10-14,16,23,26H,5,9,15,17-19H2,1H3,(H,29,34)(H,30,33)
  • InChiKey: YTKBVOLFLZTIHY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[2-[(4-methoxyphenyl)methyl-[2-oxo-1-phenyl-2-(tetrahydrofuran-2-ylmethylamino)ethyl]amino]-2-oxo-ethyl]furan-2-carboxamide
  • N-[2-[(4-methoxyphenyl)methyl-[2-oxo-1-phenyl-2-(2-tetrahydrofuranylmethylamino)ethyl]amino]-2-oxoethyl]-2-furancarboxamide
  • N-[2-keto-2-[[2-keto-1-phenyl-2-(tetrahydrofurfurylamino)ethyl]-(4-methoxybenzyl)amino]ethyl]-2-furamide
  • N-[2-[(4-methoxyphenyl)methyl-[2-oxo-2-(oxolan-2-ylmethylamino)-1-phenyl-ethyl]amino]-2-oxo-ethyl]furan-2-carboxamide
  • ASN 05989844

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Schistosoma mansoni calcium-activated potassium channel 0.0029 0.0109 0.0095
Plasmodium falciparum alpha/beta hydrolase fold domain containing protein, putative 0.0021 0.0037 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Echinococcus multilocularis ryanodine receptor 44f 0.0029 0.0109 0.0095
Echinococcus multilocularis transfer RNA-Gly 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0184 0.1367 0.1355
Loa Loa (eye worm) voltage-gated potassium channel 0.0029 0.0109 0.0095
Toxoplasma gondii hypothetical protein 0.0021 0.0037 0.0545
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0439 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0029 0.0109 0.0095
Plasmodium vivax lysophospholipase, putative 0.0021 0.0037 0.0086
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0109 0.0095
Trichomonas vaginalis set domain proteins, putative 0.0274 0.2093 0.7708
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0419 0.1503
Echinococcus granulosus sex peptide receptor 0.0095 0.0641 0.0628
Schistosoma mansoni amidase 0.1247 1 1
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.0109 0.0095
Schistosoma mansoni voltage-gated ion channel 0.0029 0.0109 0.0095
Echinococcus multilocularis G-protein coupled receptor, putative 0.0095 0.0641 0.0628
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0059 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0037 0.0086
Trypanosoma brucei monoglyceride lipase, putative 0.035 0.2712 1
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0029 0.0109 0.0095
Plasmodium falciparum esterase, putative 0.035 0.2712 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0095 0.0641 0.0628
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0029 0.0109 0.0095
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0029 0.0109 0.0095
Echinococcus granulosus voltage gated potassium channel 0.0029 0.0109 0.0095
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.015 0.1091 1
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.0419 0.1503
Brugia malayi olfactory channel protein osm-9 0.0032 0.0127 0.0113
Leishmania major hypothetical protein, conserved 0.0021 0.0037 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Brugia malayi Cyclic-nucleotide gated cation channel 0.0029 0.0109 0.0095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0029 0.0109 0.0095
Echinococcus granulosus allatostatin A receptor 0.0095 0.0641 0.0628
Echinococcus granulosus sodium channel protein 0.0029 0.0109 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0037 0.0086
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0029 0.0109 0.0095
Echinococcus multilocularis neuropeptide receptor 0.0095 0.0641 0.0628
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Toxoplasma gondii hypothetical protein 0.0021 0.0037 0.0545
Trypanosoma brucei monoglyceride lipase, putative 0.035 0.2712 1
Echinococcus granulosus hypothetical protein 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Echinococcus multilocularis hyperpolarization activated cyclic 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Onchocerca volvulus 0.0095 0.0641 0.2988
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0029 0.0109 0.0095
Echinococcus granulosus monoacylglycerol lipase abhd12 0.0021 0.0037 0.0023
Echinococcus multilocularis voltage gated potassium channel 0.0029 0.0109 0.0095
Trypanosoma brucei hypothetical protein, conserved 0.0052 0.029 0.1071
Trypanosoma cruzi Serine peptidase, Clan SC, Family S09X, putative 0.0021 0.0037 0.0086
Echinococcus multilocularis potassium voltage gated channel protein 0.0029 0.0109 0.0095
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0059 0.0167
Echinococcus multilocularis potassium voltage gated channel protein 0.0029 0.0109 0.0095
Brugia malayi hypothetical protein 0.0095 0.0641 0.0628
Mycobacterium ulcerans lysophospholipase 0.035 0.2712 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0095 0.0641 0.0628
Schistosoma mansoni adenoreceptor 0.0095 0.0641 0.0628
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0095 0.0641 0.0628
Brugia malayi hypothetical protein 0.0029 0.0109 0.0095
Brugia malayi MGC79044 protein 0.0021 0.0037 0.0023
Schistosoma mansoni opsin-like receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis g protein coupled receptor 0.0095 0.0641 0.0628
Schistosoma mansoni amine GPCR 0.0095 0.0641 0.0628
Echinococcus granulosus short transient receptor potential channel 6 0.0029 0.0109 0.0095
Echinococcus multilocularis dna polymerase eta 0.0023 0.0059 0.0045
Echinococcus multilocularis fatty acid amide hydrolase 1 0.1247 1 1
Loa Loa (eye worm) voltage-dependent calcium channel 0.0029 0.0109 0.0095
Entamoeba histolytica ;Alias 0.0021 0.0037 0.0086
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.0109 0.0095
Onchocerca volvulus 0.0095 0.0641 0.2988
Onchocerca volvulus 0.0034 0.015 0.0648
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.015 0.0136
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.035 0.2712 1
Leishmania major hypothetical protein, conserved 0.015 0.1091 0.3994
Echinococcus granulosus hyperpolarization activated cyclic 0.0029 0.0109 0.0095
Plasmodium vivax unspecified product 0.0021 0.0037 0.0086
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0439 0.1522
Schistosoma mansoni two-pore calcium channel 0.0029 0.0109 0.0095
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.0109 0.0095
Plasmodium vivax alpha/beta hydrolase, putative 0.0021 0.0037 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0059 0.0217
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0052 0.029 0.1026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0059 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0021 0.0037 0.0136
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0029 0.0109 0.0095
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.015 0.1091 0.3994
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.015 0.1091 0.3308
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0439 0.0426
Plasmodium vivax alpha/beta hydrolase, putative 0.0021 0.0037 0.0086
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0023
Echinococcus multilocularis g-protein coupled receptor 0.0095 0.0641 0.0628
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.035 0.2712 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus granulosus ryanodine receptor 44f 0.0029 0.0109 0.0095
Echinococcus granulosus two pore calcium channel protein 2 0.0029 0.0109 0.0095
Echinococcus multilocularis abhydrolase domain containing 3 0.0021 0.0037 0.0023
Mycobacterium tuberculosis Possible lysophospholipase 0.035 0.2712 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0037 0.0086
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Leishmania major DNA polymerase eta, putative 0.0023 0.0059 0.0167
Leishmania major hypothetical protein, conserved 0.0021 0.0037 0.0086
Echinococcus granulosus neuropeptide receptor 0.0095 0.0641 0.0628
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0029 0.0109 0.0095
Schistosoma mansoni amine GPCR 0.0095 0.0641 0.0628
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.035 0.2712 1
Echinococcus granulosus TRP transient receptor potential channel 0.0029 0.0109 0.0095
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.015 0.0136
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.0109 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0037 0.0086
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.015 0.0136
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0059 0.0217
Echinococcus granulosus voltage dependent calcium channel 0.0029 0.0109 0.0095
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.015 0.1091 0.1079
Echinococcus granulosus L aminoadipate semialdehyde 0.0184 0.1367 0.1355
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.035 0.2712 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0095 0.0641 0.0628
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0059 0.0167
Echinococcus granulosus biogenic amine 5HT receptor 0.0095 0.0641 0.0628
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0059 0.0167
Toxoplasma gondii transporter, cation channel family protein 0.0029 0.0109 0.2233
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0059 0.0167
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0095 0.0641 0.0628
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0037 0.0086
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0032 0.0066
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0029 0.0109 0.0095
Echinococcus granulosus potassium voltage gated channel protein 0.0029 0.0109 0.0095
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0021 0.0037 0.0086
Mycobacterium ulcerans amidase 0.015 0.1091 0.3955
Echinococcus granulosus calcium activated potassium channel 0.0029 0.0109 0.0095
Trypanosoma brucei Serine peptidase, Clan SC, Family S09X 0.0021 0.0037 0.0136
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.015 0.1091 0.4025
Plasmodium falciparum BEM46-like protein, putative 0.0021 0.0037 0.0086
Mycobacterium ulcerans hypothetical protein 0.035 0.2712 1
Echinococcus granulosus voltage dependent calcium channel 0.0029 0.0109 0.0095
Schistosoma mansoni transient receptor potential channel 0.0029 0.0109 0.0095
Brugia malayi hypothetical protein 0.0095 0.0641 0.0628
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0439 0.1522
Brugia malayi hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0029 0.0109 0.0095
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.015 0.1091 0.3308
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0095 0.0641 0.0628
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0034 0.015 0.0136
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0032 0.0066
Brugia malayi Serotonin receptor 0.0095 0.0641 0.0628
Schistosoma mansoni vesicular amine transporter 0.0029 0.0109 0.0095
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0095 0.0641 0.0628
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0021 0.0037 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Brugia malayi Protein C20orf22 0.0021 0.0037 0.0023
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0095 0.0641 0.0628
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0021 0.0037 0.0086
Plasmodium falciparum exported lipase 1 0.0021 0.0037 0.0086
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Schistosoma mansoni biogenic amine (5HT) receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis neuropeptide Y receptor 0.0095 0.0641 0.0628
Onchocerca volvulus 0.0095 0.0641 0.2988
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0059 0.0217
Schistosoma mansoni myosin xvIII 0.0095 0.0641 0.0628
Brugia malayi sulfakinin receptor protein 0.0095 0.0641 0.0628
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0032 0.0066
Giardia lamblia DINP protein human, muc B family 0.0023 0.0059 1
Brugia malayi putative amidase 0.015 0.1091 0.1079
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis conserved hypothetical protein 0.0029 0.0109 0.0095
Loa Loa (eye worm) melatonin receptor type 1A 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0023
Leishmania major monoglyceride lipase, putative 0.035 0.2712 1
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0021 0.0037 0.0086
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Echinococcus granulosus Phospholipase carboxylesterase 0.0021 0.0037 0.0023
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0029 0.0109 0.0095
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0029 0.0109 0.0095
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0032 0.0018
Plasmodium falciparum alpha/beta hydrolase, putative 0.0021 0.0037 0.0086
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.015 0.1091 0.3955
Trichomonas vaginalis conserved hypothetical protein 0.035 0.2712 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.0641 0.0628
Echinococcus multilocularis neuropeptides capa receptor 0.0095 0.0641 0.0628
Plasmodium falciparum lysophospholipase, putative 0.035 0.2712 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0302 0.1067
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0059 0.0217
Plasmodium vivax SET domain protein, putative 0.0034 0.015 0.0504
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.035 0.2712 1
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0029 0.0109 0.0352
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.0641 0.0628
Echinococcus granulosus two pore calcium channel protein 1 0.0029 0.0109 0.0095
Schistosoma mansoni neuropeptide receptor 0.0095 0.0641 0.0628
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0021 0.0037 0.0545
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0095 0.0641 0.0628
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0021 0.0037 0.0023
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0029 0.0109 0.0095
Schistosoma mansoni hypothetical protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0029 0.0109 0.0095
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0029 0.0109 0.0095
Onchocerca volvulus 0.0095 0.0641 0.2988
Echinococcus granulosus potassium voltage gated channel protein 0.0029 0.0109 0.0095
Loa Loa (eye worm) ion channel NompC 0.0029 0.0109 0.0095
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0021 0.0037 0.0136
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0641 0.0628
Leishmania major cathepsin L-like protease 0.0068 0.0419 0.1503
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0439 0.1522
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0021 0.0037 0.0086
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0184 0.1367 0.1355
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0021 0.0037 0.0086
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Plasmodium vivax unspecified product 0.0021 0.0037 0.0086
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Schistosoma mansoni hypothetical protein 0.0029 0.0109 0.0095
Toxoplasma gondii esterase/lipase/thioesterase domain-containing protein 0.0021 0.0037 0.0545
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0029 0.0109 0.0095
Brugia malayi hypothetical protein 0.0095 0.0641 0.0628
Echinococcus granulosus abhydrolase domain containing 3 0.0021 0.0037 0.0023
Leishmania major cathepsin L-like protease 0.0068 0.0419 0.1503
Echinococcus granulosus neuropeptide FF receptor 2 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Loa Loa (eye worm) G-protein coupled receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Plasmodium falciparum exported lipase 2 0.0021 0.0037 0.0086
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.0641 0.0628
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0032 0.0066
Echinococcus multilocularis potassium voltage gated channel protein 0.0029 0.0109 0.0095
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0184 0.1367 0.1355
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0021 0.0037 0.0086
Echinococcus granulosus g-protein coupled receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Schistosoma mansoni voltage-gated cation channel 0.0029 0.0109 0.0095
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0059 0.0102
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0059 0.0045
Echinococcus granulosus peptide allatostatin:somatostatin 0.0095 0.0641 0.0628
Schistosoma mansoni hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0029 0.0109 0.0095
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0059 0.0217
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.015 0.1091 0.3955
Loa Loa (eye worm) calcium channel 0.0029 0.0109 0.0095
Echinococcus multilocularis voltage gated potassium channel 0.0029 0.0109 0.0095
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0029 0.0109 0.0095
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0029 0.0109 0.0095
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0052 0.029 0.0966
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0059 0.0217
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.0372 0.1326
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Echinococcus granulosus orexin receptor type 2 0.0095 0.0641 0.0628
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0109 0.0352
Echinococcus granulosus transient receptor potential gamma protein 0.0029 0.0109 0.0095
Echinococcus granulosus fatty acid amide hydrolase 1 0.1247 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Brugia malayi hypothetical protein 0.0095 0.0641 0.0628
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Schistosoma mansoni amine GPCR 0.0095 0.0641 0.0628
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0029 0.0109 0.0095
Echinococcus granulosus sodium leak channel non selective protein 0.0029 0.0109 0.0095
Brugia malayi hypothetical protein 0.0095 0.0641 0.0628
Trypanosoma cruzi amidase, putative 0.015 0.1091 0.3994
Echinococcus granulosus neuropeptide s receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis potassium voltage gated channel protein 0.0029 0.0109 0.0095
Brugia malayi putative neuropeptide receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Echinococcus multilocularis voltage dependent calcium channel 0.0029 0.0109 0.0095
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0029 0.0109 0.0095
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0021 0.0037 0.0023
Brugia malayi ORL1-like opioid receptor 0.0095 0.0641 0.0628
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0037 0.0086
Schistosoma mansoni amine GPCR 0.0095 0.0641 0.0628
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0029 0.0109 0.0095
Brugia malayi follicle stimulating hormone receptor 0.0095 0.0641 0.0628
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0095 0.0641 0.0628
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0059 0.0167
Schistosoma mansoni transient receptor potential channel 4 0.0029 0.0109 0.0095
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0059 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Onchocerca volvulus 0.0095 0.0641 0.2988
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0029 0.0109 0.0095
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0109 0.0095
Onchocerca volvulus 0.0095 0.0641 0.2988
Brugia malayi Dopamine receptor protein 1 0.0095 0.0641 0.0628
Loa Loa (eye worm) neuropeptide F receptor 0.0095 0.0641 0.0628
Echinococcus granulosus potassium voltage gated channel protein 0.0029 0.0109 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0059 0.0217
Plasmodium vivax PST-A protein 0.0021 0.0037 0.0086
Schistosoma mansoni transient receptor potential channel 0.0029 0.0109 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0023
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0029 0.0109 0.0095
Schistosoma mansoni amine GPCR 0.0095 0.0641 0.0628
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0059 0.0102
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis potassium large conductance calcium activated 0.0029 0.0109 0.0095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0641 0.0628
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.015 0.0136
Brugia malayi Serotonin receptor 0.0095 0.0641 0.0628
Plasmodium falciparum alpha/beta-hydrolase, putative 0.0021 0.0037 0.0086
Echinococcus granulosus neuropeptide Y receptor 0.0095 0.0641 0.0628
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0029 0.0109 0.0095
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Echinococcus granulosus 7TM GPCR rhodopsin 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus granulosus shaker cognate 0.0029 0.0109 0.0095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.015 0.0136
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0059 0.0045
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0052 0.029 0.1026
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) voltage-gated potassium channel 0.0029 0.0109 0.0095
Brugia malayi GnHR receptor homolog 0.0095 0.0641 0.0628
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0095 0.0641 0.0628
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.015 0.0136
Mycobacterium ulcerans amidase 0.015 0.1091 0.3955
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0052 0.029 0.2405
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Schistosoma mansoni neuropeptide receptor 0.0095 0.0641 0.0628
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Echinococcus granulosus voltage gated potassium channel 0.0029 0.0109 0.0095
Schistosoma mansoni ap endonuclease 0.002 0.0032 0.0018
Echinococcus multilocularis serotonin receptor 0.0095 0.0641 0.0628
Echinococcus granulosus potassium large conductance calcium activated 0.0029 0.0109 0.0095
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.035 0.2712 1
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0419 0.1503
Toxoplasma gondii transporter, cation channel family protein 0.0029 0.0109 0.2233
Echinococcus multilocularis short transient receptor potential channel 6 0.0032 0.0127 0.0113
Echinococcus granulosus somatostatin receptor 0.0095 0.0641 0.0628
Plasmodium vivax PST-A protein 0.0021 0.0037 0.0086
Schistosoma mansoni opsin-like receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis allatostatin A receptor 0.0095 0.0641 0.0628
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0095 0.0641 0.0628
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.0109 0.0095
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0052 0.029 0.0966
Toxoplasma gondii transporter, cation channel family protein 0.0029 0.0109 0.2233
Plasmodium falciparum alpha/beta hydrolase, putative 0.0021 0.0037 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0037 0.0086
Echinococcus granulosus g protein coupled receptor 0.0095 0.0641 0.0628
Onchocerca volvulus 0.0095 0.0641 0.2988
Schistosoma mansoni fatty-acid amide hydrolase 0.015 0.1091 0.1079
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0029 0.0109 0.0095
Echinococcus multilocularis fatty acid amide hydrolase 1 0.015 0.1091 0.1079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0095 0.0641 0.0628
Plasmodium falciparum alpha/beta hydrolase, putative 0.0021 0.0037 0.0086
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Schistosoma mansoni biogenic amine receptor 0.0095 0.0641 0.0628
Echinococcus granulosus abhydrolase domain containing protein 13 0.0021 0.0037 0.0023
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0029 0.0109 0.0095
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0095 0.0641 0.0628
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0032 0.0018
Trypanosoma cruzi monoglyceride lipase, putative 0.035 0.2712 1
Onchocerca volvulus 0.0095 0.0641 0.2988
Plasmodium falciparum esterase, putative 0.0021 0.0037 0.0086
Brugia malayi Dopamine receptor 0.0095 0.0641 0.0628
Brugia malayi Pre-SET motif family protein 0.024 0.1823 0.1812
Brugia malayi Amidase family protein 0.015 0.1091 0.1079
Schistosoma mansoni neuropeptide receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0095 0.0641 0.0628
Trypanosoma brucei unspecified product 0.0023 0.0059 0.0217
Echinococcus multilocularis dro:myosuppressin receptor 0.0095 0.0641 0.0628
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0059 0.0217
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Onchocerca volvulus 0.0095 0.0641 0.2988
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0059 0.0045
Schistosoma mansoni neuropeptide f receptor 76f 0.0095 0.0641 0.0628
Echinococcus multilocularis Phospholipase carboxylesterase 0.0021 0.0037 0.0023
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0059 0.0045
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0029 0.0109 0.0095
Echinococcus multilocularis g protein coupled receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0029 0.0109 0.0095
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Toxoplasma gondii hypothetical protein 0.0029 0.0109 0.2233
Mycobacterium ulcerans hypothetical protein 0.0021 0.0037 0.002
Loa Loa (eye worm) amidase 0.015 0.1091 0.1079
Plasmodium vivax PST-A protein 0.0021 0.0037 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0641 0.0628
Entamoeba histolytica hypothetical protein 0.0021 0.0037 0.0086
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0641 0.0628
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.015 0.1091 0.1079
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.0641 0.0628
Echinococcus granulosus tachykinin peptides receptor 99D 0.0095 0.0641 0.0628
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.024 0.1823 0.1812
Schistosoma mansoni 60S ribosomal protein L21 0.0029 0.0109 0.0095
Brugia malayi neuropeptide F receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0029 0.0109 0.0095
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0029 0.0109 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Onchocerca volvulus 0.0095 0.0641 0.2988
Echinococcus multilocularis sodium leak channel non selective protein 0.0029 0.0109 0.0095
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0029 0.0109 0.0095
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0439 0.0426
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0059 0.0167
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0029 0.0109 0.0401
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Brugia malayi Tachykinin-like peptides receptor 99D 0.0095 0.0641 0.0628
Leishmania major phosphopantetheinyl transferase-like protein 0.0052 0.029 0.1026
Echinococcus multilocularis two pore calcium channel protein 2 0.0029 0.0109 0.0095
Onchocerca volvulus 0.0095 0.0641 0.2988
Schistosoma mansoni neuropeptide receptor 0.0095 0.0641 0.0628
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.015 0.1091 0.3955
Onchocerca volvulus 0.0276 0.2111 1
Echinococcus multilocularis neuropeptide s receptor 0.0095 0.0641 0.0628
Echinococcus granulosus g protein coupled receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0029 0.0109 0.0095
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) neuropeptide F receptor 0.0095 0.0641 0.0628
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0029 0.0109 0.0095
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Echinococcus granulosus fatty acid amide hydrolase 1 0.1247 1 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Brugia malayi G-protein coupled receptor 0.0095 0.0641 0.0628
Mycobacterium ulcerans hypothetical protein 0.0021 0.0037 0.002
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0052 0.029 0.6501
Onchocerca volvulus 0.0095 0.0641 0.2988
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0023
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0029 0.0109 0.0095
Schistosoma mansoni hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0029 0.0109 0.0095
Brugia malayi MGC83647 protein 0.0021 0.0037 0.0023
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.015 0.1091 0.3994
Echinococcus multilocularis sodium channel protein 0.0029 0.0109 0.0095
Mycobacterium ulcerans amidase 0.015 0.1091 0.3955
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.015 0.1091 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0439 0.0426
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.015 0.1091 1
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0052 0.029 0.2444
Mycobacterium ulcerans amidase 0.015 0.1091 0.3955
Echinococcus granulosus G protein coupled receptor 139 0.0095 0.0641 0.0628
Echinococcus multilocularis neuropeptide FF receptor 2 0.0095 0.0641 0.0628
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0109 0.0095
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0032 0.0066
Schistosoma mansoni voltage-dependent calcium channel 0.0029 0.0109 0.0095
Schistosoma mansoni DNA polymerase eta 0.0023 0.0059 0.0045
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0029 0.0109 0.0401
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.0641 0.0628
Onchocerca volvulus 0.0095 0.0641 0.2988
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis calcium activated potassium channel 0.0029 0.0109 0.0095
Echinococcus multilocularis two pore calcium channel protein 1 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Trichomonas vaginalis valacyclovir hydrolase, putative 0.035 0.2712 1
Plasmodium falciparum lysophospholipase, putative 0.0021 0.0037 0.0086
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0439 0.0426
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Trypanosoma cruzi serine peptidase, putative 0.0021 0.0037 0.0086
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0095 0.0641 0.0628
Echinococcus multilocularis transient receptor potential cation channel 0.0032 0.0127 0.0113
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0109 0.0095
Toxoplasma gondii hypothetical protein 0.0029 0.0109 0.2233
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0029 0.0109 0.2233
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0641 0.0628
Brugia malayi cation channel family protein 0.0029 0.0109 0.0095
Echinococcus granulosus dna polymerase kappa 0.0023 0.0059 0.0045
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0021 0.0037 0.0086
Echinococcus granulosus biogenic amine 5HT receptor 0.0095 0.0641 0.0628
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0095 0.0641 0.0628
Brugia malayi neuropeptide F receptor 0.0095 0.0641 0.0628
Plasmodium falciparum alpha/beta hydrolase, putative 0.0021 0.0037 0.0086
Plasmodium falciparum lysophospholipase, putative 0.035 0.2712 1
Loa Loa (eye worm) voltage-gated calcium channel 0.0029 0.0109 0.0095
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0095 0.0641 0.0628
Onchocerca volvulus 0.0095 0.0641 0.2988
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0029 0.0109 0.0095
Plasmodium vivax PST-A protein 0.0021 0.0037 0.0086
Toxoplasma gondii hypothetical protein 0.0021 0.0037 0.0545
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Schistosoma mansoni growth hormone secretagogue receptor 0.0095 0.0641 0.0628
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0439 0.1522
Toxoplasma gondii hypothetical protein 0.0021 0.0037 0.0545
Echinococcus multilocularis fmrfamide receptor 0.0095 0.0641 0.0628
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.035 0.2712 1
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.015 0.3193
Brugia malayi hypothetical protein 0.0095 0.0641 0.0628
Schistosoma mansoni fatty-acid amide hydrolase 0.1247 1 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0095 0.0641 0.0628
Echinococcus granulosus potassium voltage gated channel protein 0.0029 0.0109 0.0095
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0095 0.0641 0.0628
Echinococcus granulosus neuropeptide receptor A26 0.0095 0.0641 0.0628
Echinococcus multilocularis sex peptide receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0045
Brugia malayi ion channel NompC 0.0029 0.0109 0.0095
Echinococcus granulosus neuropeptides capa receptor 0.0095 0.0641 0.0628
Plasmodium falciparum epoxide hydrolase 2 0.0021 0.0037 0.0086
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Leishmania major cathepsin L-like protease 0.0068 0.0419 0.1503
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.015 0.1091 0.3955
Echinococcus multilocularis G protein coupled receptor 139 0.0095 0.0641 0.0628
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0029 0.0109 0.0095
Onchocerca volvulus 0.0184 0.1367 0.6449
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.0109 0.0095
Schistosoma mansoni histamine h1 receptor 0.0095 0.0641 0.0628
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Loa Loa (eye worm) ryanodine receptor 0.0029 0.0109 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Echinococcus multilocularis neuropeptide receptor A26 0.0095 0.0641 0.0628
Plasmodium vivax PST-A protein 0.0021 0.0037 0.0086
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.035 0.2712 1
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0029 0.0109 0.0352
Mycobacterium ulcerans hydrolase 0.0021 0.0037 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0419 0.1546
Trypanosoma cruzi serine peptidase, putative 0.0021 0.0037 0.0086
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0029 0.0109 0.0095
Plasmodium vivax PST-A protein 0.035 0.2712 1
Echinococcus multilocularis g protein coupled receptor 0.0095 0.0641 0.0628
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0059 0.0102
Echinococcus granulosus g protein coupled receptor 0.0095 0.0641 0.0628
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0052 0.029 0.0966
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0029 0.0109 0.0095
Leishmania major DNA polymerase kappa, putative 0.0023 0.0059 0.0167
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0439 0.1578
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0139 0.0126
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0032 0.0066
Brugia malayi Melatonin receptor type 1A 0.0095 0.0641 0.0628
Plasmodium falciparum lysophospholipase, putative 0.0021 0.0037 0.0086
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0029 0.0109 0.0095
Loa Loa (eye worm) TYRA-2 protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0029 0.0109 0.0095
Onchocerca volvulus 0.0095 0.0641 0.2988
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0059 0.0217
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus granulosus short transient receptor potential channel 6 0.0032 0.0127 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0059 0.0217
Echinococcus granulosus hyperpolarization activated cyclic 0.0029 0.0109 0.0095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0641 0.0628
Schistosoma mansoni biogenic amine (5HT) receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis transient receptor potential gamma protein 0.0029 0.0109 0.0095
Echinococcus granulosus alpha 1A adrenergic receptor 0.0095 0.0641 0.0628
Schistosoma mansoni alpha-1 adrenergic receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0029 0.0109 0.0095
Echinococcus granulosus voltage gated hydrogen channel 1 0.0029 0.0109 0.0095
Giardia lamblia Cgi67 serine protease precursor-like protein 0.0021 0.0037 0.1993
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Plasmodium falciparum esterase, putative 0.0021 0.0037 0.0086
Toxoplasma gondii phospholipase 0.0021 0.0037 0.0545
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Schistosoma mansoni transient receptor potential channel 0.0032 0.0127 0.0113
Echinococcus multilocularis neuropeptide Y receptor 0.0095 0.0641 0.0628
Echinococcus granulosus dro:myosuppressin receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0023
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0029 0.0109 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0037 0.0086
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.0109 0.0095
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0095 0.0641 0.0628
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0029 0.0109 0.0095
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0021 0.0037 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Brugia malayi hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Schistosoma mansoni peptidase 0.0021 0.0037 0.0023
Echinococcus multilocularis orexin receptor type 2 0.0095 0.0641 0.0628
Trypanosoma cruzi amidase, putative 0.015 0.1091 0.3994
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0032 0.0066
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Echinococcus multilocularis fmrfamide receptor 0.0095 0.0641 0.0628
Toxoplasma gondii protein c14orf29, putative 0.0021 0.0037 0.0545
Echinococcus granulosus potassium voltage gated channel protein 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0059 0.0217
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0021 0.0037 0.0545
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0095 0.0641 0.0628
Loa Loa (eye worm) amidase 0.015 0.1091 0.1079
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0029 0.0109 0.0095
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0059 0.0045
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0032 0.0018
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0109 0.0352
Echinococcus granulosus dna polymerase eta 0.0023 0.0059 0.0045
Loa Loa (eye worm) hypothetical protein 0.0032 0.0127 0.0113
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0029 0.0109 0.0095
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.015 0.1091 0.3955
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0419 0.1503
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0052 0.029 0.2444
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0029 0.0109 0.2233
Echinococcus multilocularis shaker cognate 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis voltage dependent calcium channel 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Leishmania major Bem46-like serine peptidase,Serine peptidase, Clan SC, Family S09X 0.0021 0.0037 0.0086
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Mycobacterium ulcerans amidase 0.015 0.1091 0.3955
Brugia malayi AKH receptor 0.0095 0.0641 0.0628
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.1247 1 1
Echinococcus granulosus fmrfamide receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis fatty acid amide hydrolase 1 0.1247 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0037 0.0086
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0037 0.0086
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0052 0.029 0.6501
Onchocerca volvulus 0.0095 0.0641 0.2988
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0021 0.0037 0.0086
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0059 0.0045
Echinococcus multilocularis L aminoadipate semialdehyde 0.0184 0.1367 0.1355
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0032 0.0018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.0641 0.0628
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.015 0.1091 0.3955
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Plasmodium vivax lysophospholipase, putative 0.0021 0.0037 0.0086
Brugia malayi Pre-SET motif family protein 0.0034 0.015 0.0136
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0095 0.0641 0.0628
Leishmania major hypothetical protein, unknown function 0.0029 0.0109 0.0352
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0029 0.0109 0.0095
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.015 0.0136
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0037 0.002
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0029 0.0109 0.0352
Echinococcus multilocularis serotonin receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.035 0.2712 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0095 0.0641 0.0628
Schistosoma mansoni ap endonuclease 0.002 0.0032 0.0018
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0029 0.0109 0.0095
Echinococcus granulosus neuropeptide receptor 0.0095 0.0641 0.0628
Toxoplasma gondii phospholipase/carboxylesterase 0.0021 0.0037 0.0545
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0641 0.0628
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.0641 0.0628
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0095 0.0641 0.0628
Onchocerca volvulus 0.0029 0.0109 0.0453
Echinococcus granulosus transient receptor potential cation channel 0.0032 0.0127 0.0113
Brugia malayi larval opioid receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis short transient receptor potential channel 6 0.0029 0.0109 0.0095
Echinococcus multilocularis neuropeptides capa receptor 0.0095 0.0641 0.0628
Echinococcus granulosus fatty acid amide hydrolase 1 0.015 0.1091 0.1079
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0095 0.0641 0.0628
Leishmania major hypothetical protein, conserved 0.0029 0.0109 0.0352
Echinococcus granulosus serotonin receptor 0.0095 0.0641 0.0628
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0032 0.0066
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0059 0.0167
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0059 0.0045
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Brugia malayi hypothetical protein 0.0095 0.0641 0.0628
Brugia malayi Dopamine receptor protein 2 0.0095 0.0641 0.0628
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0021 0.0037 0.0086
Plasmodium falciparum alpha/beta hydrolase, putative 0.0021 0.0037 0.0086
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0032 0.0116
Loa Loa (eye worm) G-protein coupled receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0641 0.0628
Mycobacterium ulcerans peptide amidase, GatA 0.015 0.1091 0.3955
Echinococcus multilocularis hyperpolarization activated cyclic 0.0029 0.0109 0.0095
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0059 0.0102
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0029 0.0109 0.0095
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.015 0.1091 0.1079
Plasmodium falciparum lysophospholipase, putative 0.035 0.2712 1
Plasmodium vivax lysophospholipase, putative 0.0021 0.0037 0.0086
Onchocerca volvulus Neuropeptide F receptor homolog 0.0095 0.0641 0.2988
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0029 0.0109 0.0453
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0037 0.0086
Plasmodium falciparum prodrug activation and resistance esterase 0.0021 0.0037 0.0086
Schistosoma mansoni neuropeptide F-like receptor 0.0095 0.0641 0.0628
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0029 0.0109 0.0095
Echinococcus multilocularis somatostatin receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0029 0.0109 0.0095
Brugia malayi Amidase family protein 0.015 0.1091 0.1079
Brugia malayi Transient-receptor-potential like protein 0.0029 0.0109 0.0095
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0029 0.0109 0.0095
Brugia malayi cation channel family protein 0.0029 0.0109 0.0095
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0029 0.0109 0.0095
Entamoeba histolytica hypothetical protein 0.0052 0.029 0.1026
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0029 0.0109 0.0095
Brugia malayi putative neuropeptide receptor NPR1 0.0095 0.0641 0.0628
Echinococcus multilocularis monoacylglycerol lipase abhd12 0.0021 0.0037 0.0023
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0029 0.0109 0.0095
Brugia malayi RE15519p 0.0095 0.0641 0.0628
Schistosoma mansoni ryanodine receptor related 0.0029 0.0109 0.0095
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0029 0.0109 0.0095
Brugia malayi G-protein coupled receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0029 0.0109 0.0095
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0021 0.0037 0.0086
Brugia malayi voltage-dependent calcium channel 0.0029 0.0109 0.0095
Echinococcus granulosus neuropeptides capa receptor 0.0095 0.0641 0.0628
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0021 0.0037 0.0086
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus granulosus neuropeptide Y receptor 0.0095 0.0641 0.0628
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.0109 0.0095
Schistosoma mansoni opsin-like receptor 0.0095 0.0641 0.0628
Schistosoma mansoni biogenic amine receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0029 0.0109 0.0095
Entamoeba histolytica hypothetical protein 0.0021 0.0037 0.0086
Schistosoma mansoni neuropeptide F-like receptor 0.0095 0.0641 0.0628
Echinococcus granulosus hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.0109 0.0095
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0628
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0029 0.0109 0.0095
Echinococcus multilocularis transient receptor potential cation channel 0.0032 0.0127 0.0113
Schistosoma mansoni biogenic amine receptor 0.0095 0.0641 0.0628
Toxoplasma gondii exonuclease III APE 0.002 0.0032 0.0418
Schistosoma mansoni hypothetical protein 0.0095 0.0641 0.0628
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0059 0.0217
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0095 0.0641 0.2988
Brugia malayi G protein-coupled receptor 0.0095 0.0641 0.0628
Echinococcus multilocularis neuropeptide receptor 0.0095 0.0641 0.0628
Brugia malayi hypothetical protein 0.0095 0.0641 0.0628
Onchocerca volvulus 0.0095 0.0641 0.2988
Toxoplasma gondii peptidase S15, putative 0.0021 0.0037 0.0545
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0059 0.0167
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0109 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0037 0.0086
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0059 0.0217
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.0641 0.0628
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0029 0.0109 0.0453
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0641 0.0628
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0021 0.0037 0.0086
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0095 0.0641 0.0628
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.0641 0.0628
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0029 0.0109 0.0095

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 2.3323 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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