Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0266 | 0.3118 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0629 | 0.0608 |
Brugia malayi | Isocitrate dehydrogenase | 0.0035 | 0.0122 | 0.0392 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0125 | 0.1296 | 0.4156 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0629 | 0.6816 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Schistosoma mansoni | nuclear hormone receptor | 0.0266 | 0.3118 | 0.3593 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0125 | 0.1296 | 0.1408 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0629 | 0.0608 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.021 | 0.0259 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.0365 | 0.117 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0207 | 0.0665 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0266 | 0.3118 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.0365 | 0.117 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0188 | 0.0079 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0266 | 0.3118 | 0.3033 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0125 | 0.1296 | 0.4156 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.3118 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0 | 0.5 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.149 | 0.4237 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0141 | 0.1491 | 0.4782 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.021 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0145 | 0.0464 |
Echinococcus granulosus | FTZ F1 alpha | 0.0266 | 0.3118 | 0.3593 |
Brugia malayi | nuclear receptor RXR | 0.0141 | 0.1491 | 0.4782 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0125 | 0.1296 | 0.4156 |
Onchocerca volvulus | 0.0125 | 0.1296 | 0.4156 | |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0125 | 0.1296 | 0.1408 |
Onchocerca volvulus | 0.0125 | 0.1296 | 0.4156 | |
Brugia malayi | hypothetical protein | 0.0074 | 0.0629 | 0.2018 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0266 | 0.3118 | 0.3593 |
Brugia malayi | conserved hypotetical protein | 0.0125 | 0.1296 | 0.4156 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0125 | 0.1296 | 0.4156 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0266 | 0.3118 | 0.3593 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0678 | 0.8461 | 0.8442 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0141 | 0.1491 | 0.1642 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0266 | 0.3118 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.0365 | 0.117 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0125 | 0.1296 | 0.1408 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.0553 | 0.1774 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0266 | 0.3118 | 0.3033 |
Echinococcus granulosus | expressed conserved protein | 0.0091 | 0.0847 | 0.087 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0266 | 0.3118 | 1 |
Brugia malayi | steroid hormone receptor | 0.0266 | 0.3118 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.1491 | 0.4782 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.1491 | 0.4782 |
Brugia malayi | hypothetical protein | 0.0141 | 0.1491 | 0.4782 |
Brugia malayi | isocitrate dehydrogenase | 0.0035 | 0.0122 | 0.0392 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0125 | 0.1296 | 0.4156 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0125 | 0.1296 | 0.1188 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0138 | 0.1462 | 0.1356 |
Echinococcus granulosus | tar DNA binding protein | 0.0068 | 0.0553 | 0.0517 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0125 | 0.1296 | 0.1408 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0125 | 0.1296 | 0.1188 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0035 | 0.0122 | 0.0347 |
Brugia malayi | nuclear receptor NHR-88 | 0.0125 | 0.1296 | 0.4156 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0145 | 0.0027 |
Brugia malayi | nuclear hormone receptor | 0.0266 | 0.3118 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0266 | 0.3118 | 0.3593 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0125 | 0.1296 | 0.1188 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0125 | 0.1296 | 0.1188 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.149 | 0.403 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0553 | 0.0517 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0678 | 0.8461 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.0553 | 0.1774 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0553 | 0.0517 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0629 | 0.0513 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.0207 | 0.0665 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0266 | 0.3118 | 0.3033 |
Brugia malayi | hypothetical protein | 0.0141 | 0.1491 | 0.4782 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.0553 | 0.1774 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0266 | 0.3118 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0138 | 0.1462 | 0.1606 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0266 | 0.3118 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0266 | 0.3118 | 0.3033 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0125 | 0.1296 | 0.1408 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0156 | 0.1696 | 1 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0035 | 0.0122 | 0.5 |
Brugia malayi | RNA binding protein | 0.0068 | 0.0553 | 0.1774 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0266 | 0.3118 | 0.3033 |
Schistosoma mansoni | nuclear receptor | 0.0125 | 0.1296 | 0.1408 |
Schistosoma mansoni | zinc finger protein | 0.0125 | 0.1296 | 0.1408 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Brugia malayi | tailless protein | 0.0125 | 0.1296 | 0.4156 |
Brugia malayi | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.1491 | 0.4782 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0283 | 0.0163 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.0207 | 0.0102 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0328 | 0.0608 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0266 | 0.3118 | 0.3593 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.014 | 0.149 | 0.403 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.0207 | 0.0665 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0266 | 0.3118 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0266 | 0.3118 | 0.3593 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.3118 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0266 | 0.3118 | 1 |
Brugia malayi | ecdysone receptor | 0.0125 | 0.1296 | 0.4156 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0097 | 0.0923 | 0.2961 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0125 | 0.1296 | 0.1188 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0035 | 0.0122 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0328 | 0.1053 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0266 | 0.3118 | 0.3593 |
Brugia malayi | nuclear receptor NHR-67 | 0.0125 | 0.1296 | 0.4156 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0125 | 0.1296 | 0.4156 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0266 | 0.3118 | 0.3593 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0266 | 0.3118 | 0.3593 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0629 | 0.0608 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.0207 | 0.0102 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.029 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0266 | 0.3118 | 0.3593 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0297 | 0.3517 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0297 | 0.3517 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0297 | 0.3517 | 1 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.0207 | 0.0102 |
Schistosoma mansoni | nuclear hormone receptor | 0.0125 | 0.1296 | 0.1408 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0553 | 0.0517 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0266 | 0.3118 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0125 | 0.1296 | 0.1408 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0125 | 0.1296 | 0.1408 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0266 | 0.3118 | 0.3033 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0141 | 0.1491 | 0.1642 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0266 | 0.3118 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0553 | 0.0517 |
Brugia malayi | nuclear hormone receptor | 0.0125 | 0.1296 | 0.4156 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0145 | 0.0464 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0266 | 0.3118 | 0.3593 |
Brugia malayi | ecdysteroid receptor | 0.0266 | 0.3118 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0266 | 0.3118 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0125 | 0.1296 | 0.4156 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0097 | 0.0923 | 1 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.0553 | 0.1774 |
Mycobacterium ulcerans | hypothetical protein | 0.0156 | 0.1696 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0141 | 0.1491 | 0.1386 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.021 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.3118 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0266 | 0.3118 | 0.3033 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0125 | 0.1296 | 0.4156 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0125 | 0.1296 | 0.1408 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0188 | 0.0079 |
Loa Loa (eye worm) | DR-78 | 0.0125 | 0.1296 | 0.4156 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0207 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0141 | 0.1491 | 0.4782 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.0553 | 0.1774 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.0207 | 0.0086 |
Schistosoma mansoni | nuclear receptor | 0.0125 | 0.1296 | 0.1408 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0923 | 0.2961 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0035 | 0.0122 | 0.0392 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0266 | 0.3118 | 0.3593 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0266 | 0.3118 | 1 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.021 | 0.0259 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0629 | 0.6816 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0097 | 0.0923 | 0.0811 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0266 | 0.3118 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0266 | 0.3118 | 0.3033 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0266 | 0.3118 | 0.3593 |
Schistosoma mansoni | coup transcription factor | 0.0266 | 0.3118 | 0.3593 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0266 | 0.3118 | 0.3033 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0297 | 0.3517 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0266 | 0.3118 | 0.3593 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0266 | 0.3118 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0141 | 0.1491 | 0.4782 |
Schistosoma mansoni | nuclear hormone receptor | 0.0125 | 0.1296 | 0.1408 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0678 | 0.8461 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0266 | 0.3118 | 0.3593 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.1491 | 0.4782 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0266 | 0.3118 | 0.3593 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0125 | 0.1296 | 0.4156 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0125 | 0.1296 | 0.1188 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0266 | 0.3118 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0125 | 0.1296 | 0.4156 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0266 | 0.3118 | 0.3593 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0266 | 0.3118 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0629 | 0.6816 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.0207 | 0.0086 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0266 | 0.3118 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0125 | 0.1296 | 0.1408 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0141 | 0.1491 | 0.1642 |
Echinococcus multilocularis | tar DNA binding protein | 0.0068 | 0.0553 | 0.0436 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.3118 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0266 | 0.3118 | 0.3593 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0125 | 0.1296 | 0.4156 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.3118 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0553 | 0.0517 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0266 | 0.3118 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0266 | 0.3118 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0266 | 0.3118 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0266 | 0.3118 | 0.3593 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0629 | 0.6816 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0188 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0365 | 0.117 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0266 | 0.3118 | 0.3593 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0098 | 0.0943 | 0.0984 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0188 | 0.0079 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0035 | 0.0122 | 0.0721 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0125 | 0.1296 | 0.4156 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0097 | 0.0923 | 0.0961 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0266 | 0.3118 | 1 |
Echinococcus multilocularis | expressed conserved protein | 0.0091 | 0.0847 | 0.0734 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.1491 | 0.4782 |
Onchocerca volvulus | 0.0266 | 0.3118 | 1 | |
Brugia malayi | hypothetical protein | 0.0125 | 0.1296 | 0.4156 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | = 21.6 uM | Tested for cytotoxicity against human cancer cell lines HL-60(TB) (leukemia) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 21.6 uM | Tested for cytotoxicity against human cancer cell lines HL-60(TB) (leukemia) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 49.1 uM | Tested for cytotoxicity against COLO 205 (colon cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 49.1 uM | Tested for cytotoxicity against COLO 205 (colon cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | Tested for cytotoxicity against NCI-H522 (non-small-cell lung cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | Tested for cytotoxicity against DMS 273 (small-cell lung cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | In vitro cytotoxicity against SF-295 (CNS cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | Tested for cytotoxicity against M14 melanoma | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | Tested for cytotoxicity against OVCAR-3 (ovarian cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | Tested for cytotoxicity against CAKI-1 renal cancer | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | Tested for cytotoxicity against NCI-H522 (non-small-cell lung cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | Tested for cytotoxicity against DMS 273 (small-cell lung cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | In vitro cytotoxicity against SF-295 (CNS cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | Tested for cytotoxicity against M14 melanoma | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | Tested for cytotoxicity against OVCAR-3 (ovarian cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | > 100 uM | Tested for cytotoxicity against CAKI-1 renal cancer | ChEMBL. | 8410995 |
IC50 (functional) | > 40 uM | In vitro inhibition of bovine electrophoretically homogeneous tubulin polymerization. | ChEMBL. | 8410995 |
IC50 (functional) | > 40 uM | In vitro inhibition of bovine electrophoretically homogeneous tubulin polymerization. | ChEMBL. | 8410995 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.