Detailed information for compound 1575752

Basic information

Technical information
  • TDR Targets ID: 1575752
  • Name: 4-ETHYLBENZALDEHYDE
  • MW: 134.175 | Formula: C9H10O
  • H donors: 0 H acceptors: 1 LogP: 2.18 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc(cc1)C=O
  • InChi: 1S/C9H10O/c1-2-8-3-5-9(7-10)6-4-8/h3-7H,2H2,1H3
  • InChiKey: QNGNSVIICDLXHT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4748-78-1
  • 53951-50-1
  • Ethyl benzaldehyde
  • ST5213337
  • BENZALDEHYDE,4-ETHYL
  • InChI=1/C9H10O/c1-2-8-3-5-9(7-10)6-4-8/h3-7H,2H2,1H
  • Benzaldehyde, 4-ethyl-
  • Benzaldehyde, P-ethyl-
  • EINECS 225-268-8
  • Ethylbenzaldehyde, p-
  • FEMA No. 3756
  • ZINC02003388
  • 233633_ALDRICH
  • Benzaldehyde, ethyl-
  • ETHYLBENZALDEHYDE
  • W375608_ALDRICH
  • p-Ethylbenzaldehyde

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Pre-SET motif family protein 0.0204 0.0761 0.1594
Loa Loa (eye worm) neuropeptide F receptor 0.0314 0.1213 0.2543
Loa Loa (eye worm) RecQ helicase 0.0065 0.0193 0.0405
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.006 0.0117
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0141 0.0505 0.1059
Entamoeba histolytica recQ family helicase, putative 0.0035 0.007 0.0137
Loa Loa (eye worm) hypothetical protein 0.0134 0.0475 0.0995
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0059 0.0115
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0001 0.0002
Onchocerca volvulus 0.0314 0.1213 0.2543
Schistosoma mansoni ap endonuclease 0.0019 0.0005 0.001
Echinococcus granulosus adenylate cyclase 9 0.0082 0.0262 0.055
Mycobacterium ulcerans hypothetical protein 0.0042 0.0099 0.0554
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus granulosus tm gpcr rhodopsin 0.0314 0.1213 0.2543
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0005 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0123
Echinococcus multilocularis nmda type glutamate receptor 0.02 0.0747 0.0747
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0059 0.0115
Schistosoma mansoni opsin-like receptor 0.0314 0.1213 0.2568
Trypanosoma brucei adenosine transporter 2, putative 0.0206 0.077 0.162
Echinococcus granulosus glutamate receptor 2 0.0038 0.0085 0.0177
Echinococcus granulosus serotonin receptor 0.0314 0.1213 0.2543
Echinococcus multilocularis neuropeptide s receptor 0.0759 0.303 0.303
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0157 0.057 0.1192
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus multilocularis g protein coupled receptor 0.0314 0.1213 0.1213
Schistosoma mansoni hypothetical protein 0.0314 0.1213 0.2568
Echinococcus granulosus biogenic amine 5HT receptor 0.0314 0.1213 0.2543
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0303 0.1168 0.244
Entamoeba histolytica nucleoside transporter, putative 0.1185 0.4772 1
Brugia malayi neuropeptide F receptor 0.0314 0.1213 0.2543
Echinococcus multilocularis GPCR, family 2 0.0018 0.0001 0.0001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0314 0.1213 0.2543
Echinococcus multilocularis expressed protein 0.0365 0.1421 0.1421
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0002
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0455 0.1789 0.3779
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.0059 0.0121
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0005 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.1213 0.2568
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0415 0.0877
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0002
Trypanosoma cruzi nucleobase transporter, putative 0.0206 0.077 0.162
Entamoeba histolytica hypothetical protein 0.0038 0.0084 0.0168
Brugia malayi G protein-coupled receptor 0.0314 0.1213 0.2543
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0415 0.0415
Echinococcus multilocularis fmrfamide receptor 0.0314 0.1213 0.1213
Mycobacterium ulcerans arylsulfatase, AslA 0.0018 0.0001 0.0006
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0314 0.1213 0.1213
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0043 0.0105 0.0214
Echinococcus granulosus thioredoxin glutathione reductase 0.0092 0.0304 0.0637
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0314 0.1213 0.2568
Brugia malayi hypothetical protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0314 0.1213 0.2543
Schistosoma mansoni netrin receptor unc5 0.003 0.005 0.0106
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0059 0.0115
Echinococcus granulosus lamin dm0 0.0026 0.0035 0.0073
Brugia malayi G-protein coupled receptor 0.0314 0.1213 0.2543
Brugia malayi ORL1-like opioid receptor 0.0314 0.1213 0.2543
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0005 0.0039
Brugia malayi sulfakinin receptor protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus multilocularis serotonin receptor 0.0314 0.1213 0.1213
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0134 0.0475 0.0475
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0206 0.077 0.162
Trypanosoma cruzi ribokinase, putative 0.0134 0.0475 0.0997
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.0024 0.005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0314 0.1213 0.1213
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3779
Trypanosoma brucei adenosine transporter 2 0.0206 0.077 0.162
Entamoeba histolytica hypothetical protein 0.0038 0.0084 0.0168
Loa Loa (eye worm) hypothetical protein 0.0134 0.0475 0.0995
Mycobacterium tuberculosis Putative ferredoxin reductase 0.021 0.0786 0.8913
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0042 0.0099 0.0208
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.006 0.031
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0059 0.0115
Trypanosoma brucei nucleoside transporter 1, putative 0.0206 0.077 0.162
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0134 0.0475 0.5385
Schistosoma mansoni lamin 0.0026 0.0035 0.0074
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0226 0.0854 0.1789
Trypanosoma brucei trypanothione reductase 0.0092 0.0304 0.0635
Onchocerca volvulus 0.0026 0.0035 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0048 0.0101
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0314 0.1213 0.2543
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0059 0.0124
Leishmania major tagatose-6-phosphate kinase-like protein 0.0134 0.0475 0.0997
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0079
Schistosoma mansoni alpha-1 adrenergic receptor 0.0314 0.1213 0.2568
Brugia malayi Uncoordinated protein 44 0.003 0.005 0.0105
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0158 0.0331
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0059 0.0303
Brugia malayi Dopamine receptor 0.0314 0.1213 0.2543
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0055 0.0155 0.0155
Echinococcus multilocularis neuropeptide FF receptor 2 0.0314 0.1213 0.1213
Echinococcus granulosus peptide allatostatin:somatostatin 0.0314 0.1213 0.2543
Echinococcus granulosus nmda type glutamate receptor 0.0192 0.0713 0.1494
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.006 0.031
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0001 0.0001
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0415 0.086
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0092 0.0304 0.3443
Loa Loa (eye worm) hypothetical protein 0.0126 0.0442 0.0926
Entamoeba histolytica hypothetical protein 0.0019 0.0005 0.0001
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0455 0.1789 0.3779
Loa Loa (eye worm) hypothetical protein 0.0026 0.0033 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0011
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0005 0.0005
Schistosoma mansoni histamine h1 receptor 0.0314 0.1213 0.2568
Mycobacterium ulcerans arylsulfatase AtsD 0.0018 0.0001 0.0006
Echinococcus granulosus death domain containing protein 0.003 0.005 0.0105
Brugia malayi Protein kinase domain containing protein 0.0126 0.0442 0.0926
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0415 0.2318
Schistosoma mansoni neuropeptide receptor 0.0314 0.1213 0.2568
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.1174 0.4726 0.9902
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0005 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.1213 0.2543
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0056 0.0158 0.0331
Onchocerca volvulus 0.0078 0.0248 0.052
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0455 0.1789 0.1789
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0001 0.0002
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.0059 0.0328
Echinococcus multilocularis g protein coupled receptor 0.0314 0.1213 0.1213
Brugia malayi putative neuropeptide receptor 0.0314 0.1213 0.2543
Echinococcus granulosus microtubule associated protein 2 0.0667 0.2653 0.556
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0314 0.1212 0.2541
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.1168 0.2445
Schistosoma mansoni ATP-binding cassette transporter 0.0047 0.0119 0.0252
Onchocerca volvulus 0.0314 0.1213 0.2543
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0044 0.0108 0.0578
Onchocerca volvulus 0.0232 0.0877 0.1837
Brugia malayi Serotonin receptor 0.0314 0.1213 0.2543
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0059 0.0115
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Brugia malayi phosphofructokinase 0.0119 0.0415 0.0869
Loa Loa (eye worm) melatonin receptor type 1A 0.0314 0.1213 0.2543
Onchocerca volvulus 0.0314 0.1213 0.2543
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0314 0.1213 0.2568
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0298 0.1146 0.2418
Echinococcus granulosus G protein coupled receptor 139 0.0314 0.1213 0.2543
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0005 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0123
Echinococcus multilocularis netrin receptor unc 5 0.003 0.005 0.005
Schistosoma mansoni glutamate receptor NMDA 0.0047 0.0119 0.0252
Echinococcus granulosus geminin 0.0529 0.2091 0.438
Schistosoma mansoni hypothetical protein 0.0314 0.1213 0.2568
Trypanosoma cruzi nucleoside transporter-like, putative 0.0206 0.077 0.162
Loa Loa (eye worm) glutathione reductase 0.0092 0.0304 0.0637
Trypanosoma brucei adenosine transporter 2 0.0206 0.077 0.162
Echinococcus granulosus tm gpcr rhodopsin 0.0314 0.1213 0.2543
Brugia malayi 6-phosphofructokinase 0.0119 0.0415 0.0869
Echinococcus granulosus nuclear factor of activated T cells 5 0.0153 0.0552 0.1157
Echinococcus granulosus neuropeptide Y receptor 0.0314 0.1213 0.2543
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0047 0.0119 0.0119
Echinococcus granulosus neuropeptide FF receptor 2 0.0314 0.1213 0.2543
Brugia malayi Nucleoside transporter family protein 0.1185 0.4772 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0005 0.0005
Plasmodium vivax SET domain protein, putative 0.0029 0.0048 0.0242
Schistosoma mansoni intermediate filament proteins 0.0026 0.0035 0.0074
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0298 0.1146 0.2418
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3747
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0314 0.1213 0.1213
Loa Loa (eye worm) hypothetical protein 0.0206 0.077 0.1613
Echinococcus multilocularis bloom syndrome protein 0.0065 0.0193 0.0193
Echinococcus multilocularis neuropeptides capa receptor 0.0314 0.1213 0.1213
Schistosoma mansoni growth hormone secretagogue receptor 0.0314 0.1213 0.2568
Schistosoma mansoni biogenic amine receptor 0.0314 0.1213 0.2568
Onchocerca volvulus 0.0314 0.1213 0.2543
Brugia malayi AKH receptor 0.0314 0.1213 0.2543
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0455 0.1789 0.3779
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0415 0.0869
Echinococcus granulosus ribokinase 0.0134 0.0475 0.0995
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.1185 0.4772 0.4772
Brugia malayi hypothetical protein 0.0314 0.1213 0.2543
Toxoplasma gondii nucleoside transporter protein 0.0206 0.077 0.162
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0455 0.1789 1
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0298 0.1146 0.24
Echinococcus multilocularis serotonin receptor 0.0314 0.1213 0.1213
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.021 0.0786 0.8777
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0208
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0314 0.1213 0.1213
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0059 0.0115
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0157 0.0571 0.6032
Mycobacterium tuberculosis Probable dehydrogenase 0.021 0.0786 0.8913
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0455 0.1789 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0059 0.0303
Brugia malayi RE15519p 0.0314 0.1213 0.2543
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0206 0.077 0.162
Entamoeba histolytica hypothetical protein 0.0019 0.0005 0.0001
Mycobacterium ulcerans arylsulfatase AtsD 0.0018 0.0001 0.0006
Schistosoma mansoni adenoreceptor 0.0314 0.1213 0.2568
Schistosoma mansoni amine GPCR 0.0314 0.1213 0.2568
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0415 0.4698
Schistosoma mansoni biogenic amine (5HT) receptor 0.0314 0.1213 0.2568
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.1185 0.4772 1
Echinococcus granulosus lamin 0.0026 0.0035 0.0073
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0059 0.0115
Brugia malayi Melatonin receptor type 1A 0.0314 0.1213 0.2543
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0027 0.0038 0.0079
Echinococcus multilocularis lamin 0.0026 0.0035 0.0035
Schistosoma mansoni opsin-like receptor 0.0314 0.1213 0.2568
Trypanosoma cruzi hypothetical protein, conserved 0.0126 0.0442 0.0926
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0035 0.0073
Echinococcus granulosus g-protein coupled receptor 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0314 0.1213 0.2543
Brugia malayi PXA domain containing protein 0.0019 0.0005 0.0011
Trypanosoma cruzi nucleobase transporter, putative 0.0206 0.077 0.162
Loa Loa (eye worm) hypothetical protein 0.0082 0.0262 0.055
Loa Loa (eye worm) hypothetical protein 0.1185 0.4772 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0233 0.0881 1
Brugia malayi Bloom's syndrome protein homolog 0.0065 0.0193 0.0405
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0206 0.077 0.162
Brugia malayi hypothetical protein 0.0314 0.1213 0.2543
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0415 0.086
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0059 0.0303
Schistosoma mansoni neuropeptide F-like receptor 0.0314 0.1213 0.2568
Echinococcus granulosus neuropeptide s receptor 0.0759 0.303 0.6349
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0455 0.1789 0.3779
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0005 0.0011
Trypanosoma cruzi nucleobase transporter, putative 0.0206 0.077 0.162
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0005 0.0005
Loa Loa (eye worm) TK/ROR protein kinase 0.0126 0.0442 0.0926
Giardia lamblia Fructose-bisphosphate aldolase 0.0303 0.1168 0.2445
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0001 0.0002
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0134 0.0475 0.2656
Giardia lamblia Ribokinase 0.0134 0.0475 0.0993
Entamoeba histolytica hypothetical protein 0.0038 0.0084 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0005 0.0011
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0055 0.0155 0.0325
Schistosoma mansoni glutamate receptor kainate 0.0047 0.0119 0.0252
Schistosoma mansoni biogenic amine receptor 0.0314 0.1213 0.2568
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0001 0.0001
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0038 0.0186
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0059 0.0123
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0005 0.0011
Schistosoma mansoni hypothetical protein 0.0314 0.1213 0.2568
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0055 0.0155 0.0325
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0059 0.0121
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0059 0.0115
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.1213 0.1213
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0008
Schistosoma mansoni glutamate receptor NMDA 0.0239 0.0903 0.1912
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3742
Brugia malayi hypothetical protein 0.0314 0.1213 0.2543
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0455 0.1789 0.3785
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0008
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0455 0.1789 0.3747
Echinococcus granulosus 7TM GPCR rhodopsin 0.0314 0.1213 0.2543
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0206 0.077 0.162
Echinococcus multilocularis tumor protein p63 0.0379 0.1479 0.1479
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0314 0.1213 0.2568
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0415 0.2298
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0415 0.0869
Schistosoma mansoni biogenic amine (5HT) receptor 0.0314 0.1213 0.2568
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.0024 0.005
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0298 0.1147 0.2402
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0314 0.1213 0.2543
Brugia malayi GnHR receptor homolog 0.0314 0.1213 0.2543
Entamoeba histolytica kinase, PfkB family 0.0134 0.0475 0.0987
Brugia malayi Glutamate receptor 1 precursor 0.0047 0.0119 0.0249
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0455 0.1789 0.3779
Schistosoma mansoni amine GPCR 0.0314 0.1213 0.2568
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0455 0.1789 0.3779
Onchocerca volvulus Neuropeptide F receptor homolog 0.0314 0.1213 0.2543
Echinococcus granulosus somatostatin receptor 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Schistosoma mansoni neuropeptide F-like receptor 0.0314 0.1213 0.2568
Schistosoma mansoni DNA helicase recq1 0.0027 0.0038 0.008
Toxoplasma gondii kinase, pfkB family protein 0.1174 0.4726 1
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.1185 0.4772 1
Schistosoma mansoni lamin 0.0026 0.0035 0.0074
Onchocerca volvulus 0.104 0.4179 0.8757
Trypanosoma brucei adenosine transporter, putative 0.0206 0.077 0.162
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0038 0.007
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0455 0.1789 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.021 0.0786 0.8913
Echinococcus multilocularis g-protein coupled receptor 0.0314 0.1213 0.1213
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.0231 0.0231
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0415 0.0869
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0298 0.1147 0.2404
Mycobacterium leprae Probable adenosine kinase adk 0.0134 0.0475 0.4807
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0005 0.0007
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.0231 0.048
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0018 0.0001 0.0002
Echinococcus multilocularis neuropeptide receptor 0.0314 0.1213 0.1213
Echinococcus multilocularis glutamate receptor 2 0.0038 0.0085 0.0085
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0314 0.1213 0.2568
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0314 0.1213 0.2568
Trypanosoma brucei adenosine kinase, putative 0.1174 0.4726 1
Loa Loa (eye worm) hypothetical protein 0.0159 0.0578 0.1211
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0005 0.0009
Echinococcus granulosus glutamate NMDA receptor subunit 0.0047 0.0119 0.0249
Loa Loa (eye worm) neuropeptide F receptor 0.0314 0.1213 0.2543
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0059 0.0121
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0314 0.1213 0.1213
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.1213 0.2568
Trypanosoma cruzi nucleoside transporter 1, putative 0.0206 0.077 0.162
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0104 0.0104
Brugia malayi putative neuropeptide receptor NPR1 0.0314 0.1213 0.2543
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0298 0.1147 0.2402
Echinococcus granulosus tm gpcr rhodopsin 0.0314 0.1213 0.2543
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.1213 0.2568
Brugia malayi larval opioid receptor 0.0314 0.1213 0.2543
Trichomonas vaginalis set domain proteins, putative 0.0232 0.0876 0.1833
Schistosoma mansoni neuropeptide receptor 0.0314 0.1213 0.2568
Brugia malayi hypothetical protein 0.0038 0.0084 0.0177
Leishmania major trypanothione reductase 0.0092 0.0304 0.0635
Schistosoma mansoni hypothetical protein 0.0529 0.2091 0.4423
Trypanosoma cruzi adenosine kinase, putative 0.0134 0.0475 0.0997
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0231 0.048
Leishmania major nucleoside transporter 1, putative 0.0206 0.077 0.162
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.1213 0.2568
Echinococcus granulosus sex peptide receptor 0.0314 0.1213 0.2543
Onchocerca volvulus 0.0029 0.0048 0.01
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus multilocularis orexin receptor type 2 0.0314 0.1213 0.1213
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Brugia malayi Serotonin receptor 0.0314 0.1213 0.2543
Brugia malayi hypothetical protein 0.0314 0.1213 0.2543
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0159 0.0578 0.1211
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0005 0.0011
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0233 0.0881 1
Leishmania major hypothetical protein, conserved 0.0027 0.0038 0.007
Entamoeba histolytica hypothetical protein 0.0019 0.0005 0.0001
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0415 0.0869
Trypanosoma brucei ribokinase, putative 0.0134 0.0475 0.0997
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0059 0.0115
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0084 0.0179
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0038 0.0186
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.007 0.0139
Onchocerca volvulus 0.0134 0.0475 0.0995
Trypanosoma cruzi adenosine kinase, putative 0.1174 0.4726 1
Echinococcus multilocularis somatostatin receptor 0.0314 0.1213 0.1213
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0314 0.1213 0.1213
Loa Loa (eye worm) glutamate receptor 2 0.0047 0.0119 0.0249
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0027 0.0038 0.0079
Mycobacterium tuberculosis Adenosine kinase 0.0134 0.0475 0.5385
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0059 0.0115
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0005 0.0011
Echinococcus granulosus Ankyrin 0.003 0.0051 0.0107
Leishmania major tagatose-6-phosphate kinase-like protein 0.0134 0.0475 0.0997
Schistosoma mansoni opsin-like receptor 0.0314 0.1213 0.2568
Echinococcus multilocularis g protein coupled receptor 0.0314 0.1213 0.1213
Echinococcus multilocularis glutamate receptor 2 0.0047 0.0119 0.0119
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0141 0.0505 0.1059
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0159 0.0578 0.6119
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0005 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.1213 0.2543
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0314 0.1213 0.2543
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0298 0.1147 0.2404
Trichomonas vaginalis ribokinase, putative 0.0134 0.0475 0.0993
Treponema pallidum fructose-bisphosphate aldolase 0.0303 0.1168 0.652
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0455 0.1789 0.3785
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Leishmania major nucleobase transporter 0.0206 0.077 0.162
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0455 0.1789 0.3748
Entamoeba histolytica hypothetical protein 0.0038 0.0084 0.0168
Schistosoma mansoni DNA helicase recq5 0.0027 0.0038 0.008
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0011
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.006 0.031
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0048 0.01
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0314 0.1213 0.2568
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.005 0.0105
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0002
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0415 0.086
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0455 0.1789 0.3779
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.006 0.0123
Loa Loa (eye worm) hypothetical protein 0.0056 0.0155 0.0325
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0314 0.1213 0.2568
Leishmania major nucleobase transporter 0.0206 0.077 0.162
Chlamydia trachomatis endonuclease IV 0.0159 0.0578 0.3
Echinococcus granulosus nmda type glutamate receptor 0.02 0.0747 0.1566
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0005 0.0011
Echinococcus multilocularis neuropeptide receptor 0.0314 0.1213 0.1213
Onchocerca volvulus Putative pyridoxal kinase 0.0134 0.0475 0.0995
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0027 0.0038 0.0038
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0035 0.0073
Echinococcus multilocularis geminin 0.0529 0.2091 0.2091
Brugia malayi PXA domain containing protein 0.0019 0.0005 0.0011
Echinococcus multilocularis musashi 0.0026 0.0035 0.0035
Loa Loa (eye worm) G-protein coupled receptor 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0011
Schistosoma mansoni ankyrin 23/unc44 0.003 0.005 0.0106
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.021 0.0786 0.8913
Onchocerca volvulus 0.0056 0.0155 0.0325
Onchocerca volvulus 0.0126 0.0442 0.0926
Leishmania major nucleoside transporter 1, putative 0.0206 0.077 0.162
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0314 0.1213 0.2543
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.006 0.0117
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0314 0.1213 0.1213
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.1168 0.2445
Echinococcus granulosus orexin receptor type 2 0.0314 0.1213 0.2543
Plasmodium vivax thioredoxin reductase, putative 0.0092 0.0304 0.1679
Trichomonas vaginalis ribokinase, putative 0.0134 0.0475 0.0993
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.1213 0.2568
Loa Loa (eye worm) TYRA-2 protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0415 0.0869
Echinococcus granulosus biogenic amine 5HT receptor 0.0314 0.1213 0.2543
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3747
Onchocerca volvulus 0.0082 0.0262 0.055
Loa Loa (eye worm) hypothetical protein 0.1185 0.4772 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.1213 0.2543
Echinococcus granulosus adenosine kinase 0.1174 0.4726 0.9902
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0314 0.1213 0.2543
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.006 0.031
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0005 0.0011
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0314 0.1213 0.1213
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0079
Toxoplasma gondii kringle domain-containing protein 0.0126 0.0442 0.0926
Schistosoma mansoni glutamate receptor kainate 0.0047 0.0119 0.0252
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.0231 0.0485
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.006 0.0007
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0005 0.0011
Entamoeba histolytica ribokinase, putative 0.0134 0.0475 0.0987
Echinococcus multilocularis glutamate receptor 2 0.0055 0.0155 0.0155
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0059 0.0115
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0059 0.0123
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0415 0.0867
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.0231 0.0485
Plasmodium falciparum glutathione reductase 0.0032 0.0059 0.0303
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.1213 0.1213
Echinococcus multilocularis allatostatin A receptor 0.0314 0.1213 0.1213
Echinococcus granulosus dro:myosuppressin receptor 0.0314 0.1213 0.2543
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.1213 0.2568
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.1168 0.2445
Echinococcus multilocularis neuropeptide Y receptor 0.0314 0.1213 0.1213
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0005 0.0011
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0005 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.1213 0.1213
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0455 0.1789 1
Brugia malayi Adenosine kinase-like 0.1174 0.4726 0.9902
Echinococcus granulosus fmrfamide receptor 0.0314 0.1213 0.2543
Echinococcus multilocularis tissue type plasminogen activator 0.0126 0.0442 0.0442
Loa Loa (eye worm) G-protein coupled receptor 0.0314 0.1213 0.2543
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3779
Brugia malayi G-protein coupled receptor 0.0314 0.1213 0.2543
Brugia malayi hypothetical protein 0.0314 0.1213 0.2543
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.006 0.031
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0158 0.0331
Echinococcus granulosus neuropeptide receptor A26 0.0759 0.303 0.6349
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0001 0.0002
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0979 0.3931 0.3931
Brugia malayi STAT protein, DNA binding domain containing protein 0.0144 0.0517 0.1083
Schistosoma mansoni myosin xvIII 0.0314 0.1213 0.2568
Schistosoma mansoni ribokinase 0.0134 0.0475 0.1005
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0059 0.0115
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0159 0.0578 0.6551
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.007
Echinococcus granulosus bloom syndrome protein 0.0065 0.0193 0.0405
Echinococcus granulosus g protein coupled receptor 0.0314 0.1213 0.2543
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0159 0.0578 0.3213
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3742
Brugia malayi intermediate filament protein 0.0026 0.0035 0.0073
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0415 0.4034
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0126 0.0442 0.245
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0298 0.1147 0.2404
Schistosoma mansoni neuropeptide f receptor 76f 0.0314 0.1213 0.2568
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0059 0.0059
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus multilocularis thioredoxin glutathione reductase 0.0092 0.0304 0.0304
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0002
Brugia malayi Protein kinase domain containing protein 0.003 0.005 0.0105
Toxoplasma gondii endonuclease IV APN 0.0159 0.0578 0.1214
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0157 0.0571 0.6474
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0011
Onchocerca volvulus 0.0314 0.1213 0.2543
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0048 0.0101
Trypanosoma brucei adenosine kinase, putative 0.1174 0.4726 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0148 0.0534 0.6053
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Schistosoma mansoni amine GPCR 0.0314 0.1213 0.2568
Loa Loa (eye worm) hypothetical protein 0.1185 0.4772 1
Toxoplasma gondii nucleoside transporter protein 0.0206 0.077 0.162
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0314 0.1213 0.2568
Echinococcus granulosus netrin receptor unc 5 0.003 0.005 0.0105
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0141 0.0505 0.1059
Plasmodium vivax glutathione reductase, putative 0.0092 0.0304 0.1679
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0314 0.1213 0.1213
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.021 0.0786 0.8913
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0206 0.077 0.1611
Schistosoma mansoni glutamate receptor kainate 0.0047 0.0119 0.0252
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0059 0.0115
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0455 0.1789 0.3779
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0455 0.1789 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0314 0.1213 0.2568
Mycobacterium ulcerans endonuclease IV 0.0159 0.0578 0.323
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0141 0.0505 0.1058
Loa Loa (eye worm) pax transcription factor protein 2 0.0255 0.0972 0.2037
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Mycobacterium ulcerans epimerase 0.0042 0.0099 0.0554
Onchocerca volvulus 0.0314 0.1213 0.2543
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0104 0.0217
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0002
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0791 0.3162 0.6626
Echinococcus granulosus neuropeptide receptor 0.0314 0.1213 0.2543
Brugia malayi hypothetical protein 0.0134 0.0475 0.0995
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0008
Giardia lamblia Hypothetical protein 0.1185 0.4772 1
Loa Loa (eye worm) glutamate receptor 1 0.0047 0.0119 0.0249
Trichomonas vaginalis DNA helicase recq, putative 0.0065 0.0193 0.0403
Schistosoma mansoni protein kinase 0.0206 0.077 0.1628
Schistosoma mansoni amine GPCR 0.0314 0.1213 0.2568
Echinococcus granulosus allatostatin A receptor 0.0314 0.1213 0.2543
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0048 0.0101
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0005 0.0005
Brugia malayi follicle stimulating hormone receptor 0.0791 0.3162 0.6626
Trichomonas vaginalis DNA helicase recq1, putative 0.0065 0.0193 0.0403
Loa Loa (eye worm) hypothetical protein 0.0029 0.0048 0.01
Trypanosoma brucei unspecified product 0.0206 0.077 0.162
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0157 0.057 0.1194
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0055 0.0155 0.0155
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0206 0.077 0.1611
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0005 0.0011
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3779
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0057 0.0161 0.0878
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0123
Trypanosoma brucei adenosine transporter 2, putative 0.0206 0.077 0.162
Brugia malayi hypothetical protein 0.0206 0.077 0.1613
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3747
Brugia malayi hypothetical protein 0.0314 0.1213 0.2543
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0082 0.0262 0.055
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0314 0.1213 0.1213
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0455 0.1789 0.3748
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.0059 0.0328
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0011
Leishmania major adenosine kinase, putative 0.1174 0.4726 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0055 0.0155 0.0325
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.1213 0.2568
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.006 0.0116
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0059 0.0303
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0038 0.007
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Trypanosoma brucei unspecified product 0.0206 0.077 0.162
Echinococcus granulosus tumor protein p63 0.0379 0.1479 0.3098
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0005 0.0011
Onchocerca volvulus 0.0255 0.0972 0.2037
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0005 0.0011
Onchocerca volvulus 0.0314 0.1213 0.2543
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0314 0.1213 0.2543
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0314 0.1213 0.2568
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0005 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0123
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3747
Brugia malayi hypothetical protein 0.0314 0.1213 0.2543
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.1213 0.2543
Schistosoma mansoni equilibrative nucleoside transporter 0.0206 0.077 0.1628
Brugia malayi hypothetical protein 0.0018 0.0001 0.0002
Trypanosoma brucei purine nucleoside transporter 0.0206 0.077 0.162
Plasmodium falciparum glutathione reductase 0.0092 0.0304 0.1679
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0002
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.0059 0.0653
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Plasmodium falciparum cysteine repeat modular protein 1 0.0126 0.0442 0.245
Echinococcus multilocularis neuropeptide Y receptor 0.0314 0.1213 0.1213
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Trypanosoma brucei adenosine transporter 2, putative 0.0206 0.077 0.162
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0303 0.1168 0.244
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.007
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0455 0.1789 1
Schistosoma mansoni hypothetical protein 0.0314 0.1213 0.2568
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0314 0.1213 0.1213
Echinococcus granulosus glutamate receptor NMDA 0.0183 0.0677 0.1418
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0415 0.0869
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0043 0.0091
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.1213 0.1213
Echinococcus multilocularis ribokinase 0.0134 0.0475 0.0475
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0059 0.0115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.1213 0.1213
Echinococcus granulosus expressed protein 0.0365 0.1421 0.2977
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.0761 0.1594
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus multilocularis dro:myosuppressin receptor 0.0314 0.1213 0.1213
Trichomonas vaginalis DNA helicase recq, putative 0.0035 0.007 0.0144
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0455 0.1789 0.3748
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0055 0.0155 0.0155
Echinococcus granulosus neuropeptides capa receptor 0.0314 0.1213 0.2543
Echinococcus granulosus neuropeptide Y receptor 0.0314 0.1213 0.2543
Echinococcus granulosus 7tm_1 domain containing protein 0.0314 0.1213 0.2543
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0123
Brugia malayi Ribokinase 0.0134 0.0475 0.0995
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0005 0.0011
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0314 0.1213 0.2543
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0298 0.1146 0.2418
Trichomonas vaginalis conserved hypothetical protein 0.0134 0.0475 0.0993
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.1185 0.4772 1
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0206 0.077 0.162
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0027 0.0038 0.0187
Toxoplasma gondii kinase, pfkB family protein 0.0134 0.0475 0.0997
Brugia malayi hypothetical protein 0.0252 0.096 0.2011
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3742
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.1213 0.1213
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.1213 0.1213
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0206 0.077 0.1611
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0011
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.0478 0.1002
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0059 0.0303
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0314 0.1213 0.2543
Onchocerca volvulus 0.0314 0.1213 0.2543
Onchocerca volvulus 0.0314 0.1213 0.2543
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0455 0.1789 0.3785
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0314 0.1213 0.1213
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0314 0.1213 0.1213
Brugia malayi Tachykinin-like peptides receptor 99D 0.0314 0.1213 0.2543
Echinococcus multilocularis adenosine kinase 0.1174 0.4726 0.4726
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.006 0.0123
Loa Loa (eye worm) adenylyl cyclase 3 0.0082 0.0262 0.055
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Trypanosoma brucei adenosine transporter 2, putative 0.0206 0.077 0.162
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3779
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.1213 0.2568
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.1168 0.2445
Treponema pallidum NADH oxidase 0.0032 0.0059 0.0303
Brugia malayi hypothetical protein 0.1185 0.4772 1
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0455 0.1789 0.3785
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0005 0.0005
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Onchocerca volvulus 0.0314 0.1213 0.2543
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0159 0.0578 0.3213
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0206 0.077 0.1611
Onchocerca volvulus 0.0314 0.1213 0.2543
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0027 0.0038 0.0079
Loa Loa (eye worm) STAT protein 0.0144 0.0517 0.1083
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.1213 0.2543
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.003 0.005 0.005
Leishmania major hypothetical protein, conserved 0.0126 0.0442 0.0926
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0038 0.007
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0085 0.0179
Brugia malayi Death domain containing protein 0.003 0.005 0.0105
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0455 0.1789 0.3779
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.1213 0.2543
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.0155 0.0329
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0314 0.1213 0.2543
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0052 0.014 0.0293
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Leishmania major putative PfkB family sugar kinase 0.0134 0.0475 0.0997
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0141 0.0505 0.1059
Plasmodium falciparum thioredoxin reductase 0.0032 0.0059 0.0303
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0005 0.0011
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0048 0.0092
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0314 0.1213 0.2568
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0206 0.077 0.1611
Echinococcus multilocularis sex peptide receptor 0.0314 0.1213 0.1213
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0059 0.0115
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.2653 0.2653
Schistosoma mansoni biogenic amine receptor 0.0314 0.1213 0.2568
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.1185 0.4772 1
Trypanosoma cruzi trypanothione reductase, putative 0.0092 0.0304 0.0635
Echinococcus multilocularis Ankyrin 0.003 0.0051 0.0051
Brugia malayi Sulfatase family protein 0.0018 0.0001 0.0002
Trypanosoma cruzi nucleoside transporter 1, putative 0.0206 0.077 0.162
Brugia malayi hypothetical protein 0.0314 0.1213 0.2543
Giardia lamblia Sgs1 DNA helicase, putative 0.0027 0.0038 0.0077
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0005 0.0011
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.006 0.0117
Echinococcus multilocularis fmrfamide receptor 0.0314 0.1213 0.1213
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0179
Echinococcus multilocularis nmda type glutamate receptor 0.0192 0.0713 0.0713
Schistosoma mansoni amine GPCR 0.0314 0.1213 0.2568
Trypanosoma brucei ribokinase, putative 0.0134 0.0475 0.0997
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0011
Schistosoma mansoni neuropeptide receptor 0.0314 0.1213 0.2568
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0158 0.0331
Echinococcus multilocularis G-protein coupled receptor, putative 0.0314 0.1213 0.1213
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0314 0.1213 0.2568
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.1185 0.4772 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0005 0.0011
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0099 0.1114
Schistosoma mansoni glutamate receptor AMPA 0.0047 0.0119 0.0252
Echinococcus multilocularis G protein coupled receptor 139 0.0314 0.1213 0.1213
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0059 0.0303
Schistosoma mansoni hypothetical protein 0.0038 0.0085 0.0181
Echinococcus multilocularis adenylate cyclase 9 0.0082 0.0262 0.0262
Brugia malayi hypothetical protein 0.0019 0.0005 0.0011
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0148 0.0534 0.2985
Echinococcus granulosus equilibrative nucleoside transporter 0.1185 0.4772 1
Toxoplasma gondii nucleoside transporter protein 0.0206 0.077 0.162
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0233 0.0881 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0011
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0314 0.1213 0.1213
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0141 0.0505 0.1059
Brugia malayi Thioredoxin reductase 0.0092 0.0304 0.0637
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.1168 0.2445
Brugia malayi MH2 domain containing protein 0.0134 0.0478 0.1002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0005 0.0005
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.006 0.0123
Schistosoma mansoni adenosine kinase 0.1174 0.4726 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.0231 0.0476
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0084 0.0177
Echinococcus granulosus GPCR family 2 0.0018 0.0001 0.0002
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0035 0.0073
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0415 0.0869
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.003 0.005 0.0105
Schistosoma mansoni hypothetical protein 0.0038 0.0084 0.0179
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0005 0.0011
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0314 0.1212 0.2541
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.1168 0.2445
Schistosoma mansoni adenosine kinase 0.1174 0.4726 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.0231 0.0489
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0231 0.048
Schistosoma mansoni hypothetical protein 0.0126 0.0442 0.0935
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0008
Entamoeba histolytica nucleoside transporter, putative 0.0206 0.077 0.1605
Schistosoma mansoni glutamate receptor AMPA 0.0047 0.0119 0.0252
Brugia malayi hypothetical protein 0.0314 0.1213 0.2543
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0298 0.1146 0.2418
Mycobacterium tuberculosis Ribokinase RbsK 0.0134 0.0475 0.5385
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0059 0.0115
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.007 0.0139
Brugia malayi Adenylyl cyclase protein 0.0082 0.0262 0.055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.1168 0.2445
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0455 0.1789 0.3747
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0011
Brugia malayi Pax transcription factor protein 2 0.0255 0.0972 0.2037
Brugia malayi Kringle domain containing protein 0.0126 0.0442 0.0926
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) thioredoxin reductase 0.0092 0.0304 0.0637
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0231 0.048
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0059 0.0115
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0298 0.1147 0.1147
Brugia malayi neuropeptide F receptor 0.0314 0.1213 0.2543
Brugia malayi Dopamine receptor protein 1 0.0314 0.1213 0.2543
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.1213 0.2568
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0455 0.1789 0.1789
Brugia malayi Dopamine receptor protein 2 0.0314 0.1213 0.2543
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0314 0.1213 0.2543
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0011
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.2653 0.5614
Schistosoma mansoni blooms syndrome DNA helicase 0.0051 0.0138 0.0291
Trypanosoma brucei nucleoside transporter 1, putative 0.0206 0.077 0.162
Onchocerca volvulus Netrin receptor homolog 0.003 0.005 0.0105
Schistosoma mansoni ap endonuclease 0.0019 0.0005 0.001
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0233 0.0881 1
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0206 0.077 0.162
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0415 0.0867
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0042 0.0099 0.0554
Trypanosoma cruzi adenosine kinase, putative 0.0134 0.0475 0.0997
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.006 0.0007
Echinococcus granulosus intermediate filament protein 0.0026 0.0035 0.0073
Leishmania major adenosine kinase-like protein 0.0134 0.0475 0.0997
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.0079
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Trypanosoma cruzi nucleoside transporter 1, putative 0.0206 0.077 0.162
Brugia malayi 6-phosphofructokinase 0.0119 0.0415 0.0869
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0105
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.0231 0.0485
Echinococcus multilocularis lamin dm0 0.0026 0.0035 0.0035
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0059 0.0115
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.1168 0.2445
Leishmania major adenosine kinase-like protein 0.0134 0.0475 0.0997
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.0059 0.0328
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0042 0.0099 0.0208
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.007 0.0139
Brugia malayi glutathione reductase 0.0092 0.0304 0.0637
Plasmodium falciparum thioredoxin reductase 0.0092 0.0304 0.1679
Entamoeba histolytica fructokinase, putative 0.0134 0.0475 0.0987
Echinococcus multilocularis neuropeptides capa receptor 0.0314 0.1213 0.1213
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0038 0.007
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0038 0.0186
Echinococcus granulosus glutamate receptor 2 0.0055 0.0155 0.0325
Brugia malayi Pre-SET motif family protein 0.0029 0.0048 0.01
Onchocerca volvulus 0.0026 0.0035 0.0073
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0005 0.0011
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0153 0.0552 0.0552
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0059 0.0115
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0005 0.0005
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Mycobacterium ulcerans sulfatase 0.0018 0.0001 0.0006
Onchocerca volvulus Ribokinase homolog 0.0134 0.0475 0.0995
Onchocerca volvulus 0.0314 0.1213 0.2543
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.0478 0.1002
Onchocerca volvulus 0.0314 0.1213 0.2543
Mycobacterium ulcerans arylsulfatase AtsB 0.0018 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0223 0.084 0.1759
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.005 0.0105
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0415 0.0877
Echinococcus multilocularis neuropeptide receptor A26 0.0759 0.303 0.303
Brugia malayi Glutamate receptor 2 precursor 0.0047 0.0119 0.0249
Onchocerca volvulus 0.0314 0.1213 0.2543
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0134 0.0475 0.0987
Trypanosoma brucei adenosine transporter 2, putative 0.0206 0.077 0.162
Echinococcus granulosus tissue type plasminogen activator 0.0126 0.0442 0.0926
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0055 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0298 0.1147 0.2404
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0134 0.0475 0.0995
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0455 0.1789 0.3779
Echinococcus granulosus neuropeptide receptor 0.0314 0.1213 0.2543
Brugia malayi hypothetical protein 0.0019 0.0005 0.0011
Toxoplasma gondii thioredoxin reductase 0.0092 0.0304 0.0635
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.1213 0.1213
Echinococcus granulosus hypothetical protein 0.0314 0.1213 0.2543
Echinococcus granulosus tachykinin peptides receptor 99D 0.0314 0.1213 0.2543
Echinococcus granulosus neuropeptides capa receptor 0.0314 0.1213 0.2543
Mycobacterium ulcerans hydrolase 0.0018 0.0001 0.0006
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0134 0.0475 0.0987
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0008
Trypanosoma cruzi adenosine kinase, putative 0.1174 0.4726 1
Schistosoma mansoni neuropeptide receptor 0.0314 0.1213 0.2568
Trypanosoma cruzi nucleoside transporter-like, putative 0.0206 0.077 0.162
Schistosoma mansoni hypothetical protein 0.0529 0.2091 0.4423
Trypanosoma brucei purine nucleoside transporter 0.0206 0.077 0.162
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0206 0.077 0.162
Trichomonas vaginalis ribokinase, putative 0.0134 0.0475 0.0993
Echinococcus granulosus g protein coupled receptor 0.0314 0.1213 0.2543
Echinococcus granulosus equilibrative nucleoside transporter 3 0.1185 0.4772 1
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.003 0.0051 0.0108
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0415 0.0867
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0026 0.0035 0.0073
Brugia malayi hypothetical protein 0.0027 0.0038 0.0079
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0005 0.0025
Mycobacterium tuberculosis Probable reductase 0.021 0.0786 0.8913
Mycobacterium ulcerans fructokinase, PfkB 0.0134 0.0475 0.2656
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Schistosoma mansoni hypothetical protein 0.003 0.005 0.0106
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0001 0.0002
Brugia malayi G protein-coupled receptor F59B2.13 0.0314 0.1213 0.2543
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0314 0.1213 0.2543
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0005 0.0009
Onchocerca volvulus 0.0314 0.1213 0.2543
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.1185 0.4772 0.4772
Echinococcus granulosus alpha 1A adrenergic receptor 0.0314 0.1213 0.2543
Leishmania major ribokinase, putative 0.0134 0.0475 0.0997
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.003 0.0051 0.0107
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0148 0.0534 0.5559
Trypanosoma brucei adenosine transporter, putative 0.0206 0.077 0.162
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0314 0.1213 0.2543
Onchocerca volvulus 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0011
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0206 0.077 0.162
Echinococcus multilocularis glutamate receptor NMDA 0.0183 0.0677 0.0677
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0048 0.0101
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.1185 0.4772 1
Echinococcus granulosus g protein coupled receptor 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0658 0.2616 0.5481
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0314 0.1213 0.2568
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0055 0.0155 0.0325
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0415 0.0867
Entamoeba histolytica nucleoside transporter, putative 0.0206 0.077 0.1605
Onchocerca volvulus 0.0314 0.1213 0.2543
Loa Loa (eye worm) hypothetical protein 0.0314 0.1213 0.2543

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.