Detailed information for compound 1575916

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 366.501 | Formula: C16H22N4O2S2
  • H donors: 2 H acceptors: 4 LogP: 2.63 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=S(=O)(C1CC1)NCCCCCNc1scc(n1)c1ccccn1
  • InChi: 1S/C16H22N4O2S2/c21-24(22,13-7-8-13)19-11-4-1-3-10-18-16-20-15(12-23-16)14-6-2-5-9-17-14/h2,5-6,9,12-13,19H,1,3-4,7-8,10-11H2,(H,18,20)
  • InChiKey: VKOGQLTYKMJQJB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens neuropeptide Y receptor Y5 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major GTP-binding protein, putative 0.0042 0.0173 0.0152
Brugia malayi CXXC zinc finger family protein 0.003 0.0086 0.0091
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.0526
Brugia malayi cathepsin F-like cysteine proteinase 0.008 0.0452 0.0481
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0592 0.06
Plasmodium vivax unspecified product 0.008 0.0452 0.1914
Echinococcus granulosus neurogenic locus protein delta 0.0034 0.0117 0.0117
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.024 0.024
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0151 0.0151
Schistosoma mansoni calmodulin 0.005 0.0229 0.0229
Brugia malayi hypothetical protein 0.004 0.0162 0.0172
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0149 0.0442
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0018 0.0019
Echinococcus granulosus tumor protein p63 0.0342 0.235 0.235
Giardia lamblia Proteasome subunit beta type 1 0.0065 0.0343 0.1232
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0018 0.0018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0332 0.2272 0.2391
Plasmodium falciparum serine repeat antigen 5 0.008 0.0452 0.1914
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0524 0.3663 1
Onchocerca volvulus 0.0344 0.2363 0.2511
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Schistosoma mansoni notch 0.0034 0.0117 0.0117
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0018 0.0018
Echinococcus multilocularis neural cadherin 0.0034 0.0117 0.0117
Echinococcus granulosus proteasome prosome macropain subunit beta 0.004 0.0163 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0018 0.0019
Onchocerca volvulus 0.0344 0.2363 0.2511
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0138 0.087 0.0896
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0592 0.06
Echinococcus granulosus protein jagged 2 0.0034 0.0117 0.0117
Echinococcus granulosus notch 0.0034 0.0117 0.0117
Schistosoma mansoni ran 0.0042 0.0173 0.0173
Leishmania major protein kinase, putative 0.005 0.0233 0.0216
Echinococcus multilocularis calpain family protein 1, d 0.0647 0.4558 0.4558
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Trichomonas vaginalis calmodulin, putative 0.005 0.0229 0.068
Loa Loa (eye worm) RGS-3 protein 0.0039 0.0151 0.0161
Brugia malayi proteasome subunit beta type 1 0.0065 0.0343 0.0365
Loa Loa (eye worm) hypothetical protein 0.005 0.0229 0.0244
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0018 0.0018
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.024 0.0225
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2363 0.7007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0018 0.0019
Schistosoma mansoni septate junction protein 0.0034 0.0117 0.0117
Echinococcus granulosus FTZ F1 alpha 0.002 0.0018 0.0018
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Giardia lamblia Dipeptidyl-peptidase I precursor 0.008 0.0452 0.1825
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.0766 0.0766
Trypanosoma cruzi oligopeptidase b 0.0524 0.3663 0.3874
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0138 0.087 0.087
Brugia malayi Muscle positioning protein 4 0.0034 0.0117 0.0124
Echinococcus granulosus calpain 7 C02 family 0.0332 0.2272 0.2272
Schistosoma mansoni centrin-related 0.005 0.0229 0.0229
Onchocerca volvulus 0.0344 0.2363 0.2511
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0332 0.2272 0.2391
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.0645 0.1914
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0205 0.0205
Schistosoma mansoni survival motor neuron protein 0.0049 0.0228 0.0228
Brugia malayi EGF-like domain containing protein 0.0034 0.0117 0.0124
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0039 0.0151 0.0449
Plasmodium vivax importin-beta 2, putative 0.0057 0.0281 0.119
Loa Loa (eye worm) papain family cysteine protease containing protein 0.008 0.0452 0.0481
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Trypanosoma brucei I/6 autoantigen 0.005 0.0229 0.0136
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0018 0.0019
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0879 0.6238 0.6238
Schistosoma mansoni cell polarity protein 0.0034 0.0117 0.0117
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0151 0.0151
Giardia lamblia Cathepsin L-like protease 0.008 0.0452 0.1825
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.024 0.0713
Plasmodium vivax SET domain protein, putative 0.0061 0.0315 0.1335
Schistosoma mansoni hypothetical protein 0.0034 0.0117 0.0117
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0592 0.1756
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.024 0.0713
Giardia lamblia Alanyl dipeptidyl peptidase 0.0138 0.087 0.4101
Schistosoma mansoni calcium binding atopy-related autoantigen 0.005 0.0234 0.0234
Plasmodium falciparum peptidase, putative 0.0138 0.087 0.3683
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0205 0.0205
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0019
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.024 0.0225
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0039 0.0151 0.0161
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0107 0.0645 0.0601
Brugia malayi fibroinase precursor 0.008 0.0452 0.0481
Leishmania major hypothetical protein, unknown function 0.01 0.0592 0.06
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0084 0.0479 0.1972
Onchocerca volvulus Putative cubilin 0.0034 0.0117 0.0124
Loa Loa (eye worm) hypothetical protein 0.0242 0.1626 0.1728
Trichomonas vaginalis conserved hypothetical protein 0.0138 0.087 0.2581
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0344 0.2363 0.2363
Entamoeba histolytica cysteine protease, putative 0.008 0.0452 0.1429
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Schistosoma mansoni cathepsin F (C01 family) 0.0344 0.2363 0.2363
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0102 0.0109
Toxoplasma gondii troponin c, isotype gamma, putative 0.005 0.0229 0.0244
Loa Loa (eye worm) beta-lactamase 0.0107 0.0645 0.0686
Brugia malayi EGF-like domain containing protein 0.0034 0.0117 0.0124
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0929 0.6597 0.6597
Brugia malayi PXA domain containing protein 0.0039 0.0151 0.0161
Leishmania major cathepsin L-like protease 0.0344 0.2363 0.2488
Brugia malayi Animal haem peroxidase family protein 0.0304 0.2071 0.2201
Giardia lamblia Encystation-specific protease 0.008 0.0452 0.1825
Onchocerca volvulus 0.0034 0.0114 0.0121
Echinococcus multilocularis calumenin 0.005 0.0234 0.0234
Plasmodium falciparum serine repeat antigen 1 0.008 0.0452 0.1914
Schistosoma mansoni hypothetical protein 0.005 0.0229 0.0229
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0151 0.0151
Leishmania major hypothetical protein, conserved 0.01 0.0592 0.06
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0138 0.087 0.087
Trichomonas vaginalis calpain, putative 0.01 0.0592 0.1756
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0138 0.087 0.087
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0288 0.1954 0.2051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Leishmania major programmed cell death 6 protein-like protein 0.005 0.0229 0.0213
Brugia malayi cathepsin B-like cysteine proteinase 0.0751 0.5307 0.564
Onchocerca volvulus Glycogen phosphorylase homolog 0.0113 0.0688 0.0731
Onchocerca volvulus Prolyl endopeptidase homolog 0.1317 0.9409 1
Loa Loa (eye worm) calpain family protein 1 0.0879 0.6238 0.663
Plasmodium vivax calpain, putative 0.0332 0.2272 0.9616
Plasmodium vivax vivapain-2 0.0344 0.2363 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Brugia malayi Protein kinase domain containing protein 0.0022 0.003 0.0032
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0173 0.0173
Toxoplasma gondii preprocathepsin c precursor, putative 0.008 0.0452 0.0481
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0018 0.0018
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Entamoeba histolytica hypothetical protein, conserved 0.0138 0.087 0.3304
Brugia malayi Cytochrome P450 family protein 0.0032 0.0102 0.0109
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.004 0.0163 0.0142
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0039 0.0151 0.0151
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0205 0.0205
Schistosoma mansoni z-protein (S1r protein) 0.0039 0.0151 0.0151
Brugia malayi Cathepsin L-like precursor 0.0344 0.2363 0.2511
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0018 0.0019
Echinococcus multilocularis glycogen phosphorylase 0.0113 0.0688 0.0688
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Echinococcus granulosus calpain 5 0.0332 0.2272 0.2272
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.008 0.0452 0.1914
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0034 0.0114 0.0121
Trypanosoma brucei mitochondrial calcium uptake 1 0.005 0.0229 0.0136
Trypanosoma cruzi centrin-3 0.005 0.0229 0.0213
Echinococcus multilocularis calcium uptake protein 1 0.005 0.0234 0.0234
Trichomonas vaginalis calcium binding protein, putative 0.005 0.0229 0.068
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0019
Brugia malayi prolyl oligopeptidase family protein 0.0138 0.087 0.0925
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0049 0.0223 0.009
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Echinococcus granulosus Mastin 0.0034 0.0114 0.0114
Brugia malayi cathepsin F-like cysteine proteinase 0.0107 0.0644 0.0685
Echinococcus multilocularis cathepsin L cysteine protease 0.0344 0.2363 0.2363
Echinococcus granulosus cathepsin b 0.0751 0.5307 0.5307
Loa Loa (eye worm) hypothetical protein 0.0061 0.0315 0.0335
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0173 0.0183
Brugia malayi Trypsin family protein 0.0034 0.0114 0.0121
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0149 0.5
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0138 0.087 0.2581
Toxoplasma gondii prolyl endopeptidase 0.1317 0.9409 1
Brugia malayi Cadherin domain containing protein 0.0034 0.0117 0.0124
Mycobacterium ulcerans proteasome PrcB 0.0084 0.0479 0.1058
Onchocerca volvulus 0.0034 0.0114 0.0121
Mycobacterium leprae conserved hypothetical protein 0.0107 0.0645 0.0522
Echinococcus granulosus calcium uptake protein 1 0.005 0.0234 0.0234
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2363 0.7007
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.0155 0.0164
Entamoeba histolytica cysteine proteinase, putative 0.0187 0.1227 0.4903
Leishmania major hypothetical protein, conserved 0.005 0.0234 0.0218
Loa Loa (eye worm) hypothetical protein 0.0034 0.0114 0.0121
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0173 0.0183
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1317 0.9409 1
Echinococcus granulosus Regulator of G protein signaling 20 0.0039 0.0151 0.0151
Schistosoma mansoni peroxidasin 0.0304 0.2071 0.2071
Leishmania major cathepsin L-like protease 0.0344 0.2363 0.2488
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0229 0.068
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0018 0.0018
Schistosoma mansoni glycogen phosphorylase 0.0113 0.0688 0.0688
Echinococcus multilocularis acylamino acid releasing enzyme 0.0138 0.087 0.087
Schistosoma mansoni ap endonuclease 0.0039 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0107 0.0644 0.0685
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0149 0.0631
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0187 0.1227 0.1208
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0315 0.0335
Giardia lamblia Cathepsin L precursor 0.008 0.0452 0.1825
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.0766 0.0785
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1317 0.9409 0.9409
Trypanosoma brucei calpain, putative 0.01 0.0592 0.0526
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Entamoeba histolytica cysteine proteinase 2 0.0187 0.1227 0.4903
Trypanosoma cruzi cysteine peptidase, putative 0.0107 0.0644 0.0655
Leishmania major cathepsin L-like protease 0.0344 0.2363 0.2488
Leishmania major cathepsin L-like protease 0.044 0.3054 0.3224
Leishmania major centrin, putative,caltractin, putative 0.005 0.0229 0.0213
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0151 0.0151
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0149 0.0175
Entamoeba histolytica calmodulin, putative 0.005 0.0229 0.0428
Schistosoma mansoni Mername-AA248 (C02 family) 0.0332 0.2272 0.2272
Onchocerca volvulus 0.0344 0.2363 0.2511
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.008 0.0452 0.0452
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0151 0.0151
Echinococcus granulosus neurogenic locus notch protein 4 0.0034 0.0117 0.0117
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0018 0.0019
Echinococcus granulosus proteasome prosome macropain 0.0084 0.0479 0.0479
Brugia malayi carbohydrate phosphorylase 0.0113 0.0688 0.0731
Echinococcus granulosus glycoprotein Antigen 5 0.0034 0.0114 0.0114
Entamoeba histolytica glycogen phosphorylase, putative 0.0049 0.0223 0.0401
Echinococcus multilocularis cpg binding protein 0.0031 0.0098 0.0098
Echinococcus granulosus cathepsin L 0.008 0.0452 0.0452
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0018 0.0019
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0344 0.2363 1
Trypanosoma cruzi cysteine proteinase, putative 0.0187 0.1227 0.1276
Schistosoma mansoni slit 0.0034 0.0117 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.008 0.0452 0.1341
Loa Loa (eye worm) cysteine protease 0.0344 0.2363 0.2511
Echinococcus granulosus geminin 0.017 0.1099 0.1099
Entamoeba histolytica cysteine protease, putative 0.008 0.0452 0.1429
Loa Loa (eye worm) hypothetical protein 0.0138 0.087 0.0925
Schistosoma mansoni cpg binding protein 0.003 0.0086 0.0086
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.008 0.0452 0.0452
Trypanosoma cruzi hypothetical protein, conserved 0.0138 0.087 0.0896
Echinococcus multilocularis cathepsin b 0.0751 0.5307 0.5307
Entamoeba histolytica cysteine proteinase, putative 0.0187 0.1227 0.4903
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0034 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0518 0.3619 0.3846
Brugia malayi hypothetical protein 0.0036 0.0134 0.0142
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.024 0.024
Schistosoma mansoni hypothetical protein 0.0034 0.0117 0.0117
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0039 0.0155 0.0164
Brugia malayi EF hand family protein 0.005 0.0229 0.0244
Toxoplasma gondii hypothetical protein 0.01 0.0592 0.0629
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.01 0.0592 0.06
Trichomonas vaginalis calcium binding protein, putative 0.005 0.0229 0.068
Echinococcus granulosus centrin 2 0.005 0.0229 0.0229
Echinococcus multilocularis neurogenic locus notch protein 0.0034 0.0117 0.0117
Leishmania major centrin, putative 0.005 0.0229 0.0213
Toxoplasma gondii centrin 0.005 0.0229 0.0244
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.01 0.0592 0.06
Brugia malayi Proteasome A-type and B-type family protein 0.0084 0.0479 0.0509
Trichomonas vaginalis hypothetical protein 0.01 0.0592 0.1756
Trichomonas vaginalis calmodulin, putative 0.005 0.0229 0.068
Echinococcus multilocularis cysteine protease 0.0344 0.2363 0.2363
Plasmodium vivax unspecified product 0.0107 0.0644 0.2727
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Echinococcus multilocularis protein jagged 1 0.0034 0.0117 0.0117
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0018 0.0018
Echinococcus multilocularis programmed cell death protein 0.005 0.0229 0.0229
Brugia malayi EGF-like domain containing protein 0.0034 0.0117 0.0124
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Brugia malayi hypothetical protein 0.0039 0.0151 0.0161
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Loa Loa (eye worm) PXA domain-containing protein 0.0039 0.0151 0.0161
Trypanosoma cruzi I/6 autoantigen, putative 0.005 0.0229 0.0213
Leishmania major proteasome beta 5 subunit, putative 0.0084 0.0479 0.0479
Leishmania major i/6 autoantigen-like protein 0.005 0.0229 0.0213
Trypanosoma brucei Calpain-like protein CALP1.3 0.01 0.0592 0.0526
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0315 0.0315
Giardia lamblia Cysteine protease 0.008 0.0452 0.1825
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0203 0.0603
Schistosoma mansoni notch 0.0034 0.0117 0.0117
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Giardia lamblia Cathepsin L precursor 0.008 0.0452 0.1825
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0606 0.4261 0.4529
Onchocerca volvulus 0.005 0.0234 0.0249
Loa Loa (eye worm) hypothetical protein 0.0153 0.0979 0.104
Trypanosoma cruzi calmodulin, putative 0.005 0.0229 0.0213
Loa Loa (eye worm) glycogen phosphorylase 0.0113 0.0688 0.0731
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Schistosoma mansoni cathepsin F (C01 family) 0.0237 0.1588 0.1588
Leishmania major calmodulin-like protein 0.005 0.0229 0.0213
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.005 0.0233 0.0985
Echinococcus granulosus calpain 0.0332 0.2272 0.2272
Schistosoma mansoni neuronal calcium sensor 0.005 0.0229 0.0229
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.008 0.0452 0.1341
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0173 0.0152
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0114 0.0114
Brugia malayi Blistered cuticle protein 3 0.0304 0.2071 0.2201
Entamoeba histolytica cysteine protease, putative 0.008 0.0452 0.1429
Brugia malayi Cathepsin L-like precursor 0.0237 0.1588 0.1688
Trichomonas vaginalis calcineurin B subunit, putative 0.005 0.0234 0.0695
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0114 0.0114
Trypanosoma cruzi major cysteine proteinase, putative 0.0176 0.1143 0.1187
Schistosoma mansoni calpain-2 (C02 family) 0.01 0.0592 0.0592
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0107 0.0644 0.0685
Trichomonas vaginalis calcium binding protein, putative 0.005 0.0229 0.068
Trichomonas vaginalis calmodulin, putative 0.005 0.0229 0.068
Echinococcus granulosus programmed cell death protein 0.005 0.0229 0.0229
Plasmodium vivax proteasome subunit beta type-1, putative 0.0065 0.0343 0.1453
Schistosoma mansoni memapsin-2 (A01 family) 0.0447 0.3111 0.3111
Loa Loa (eye worm) programmed cell death protein 6 0.005 0.0234 0.0249
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0018 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0332 0.2272 0.2331
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Loa Loa (eye worm) hypothetical protein 0.0751 0.5307 0.564
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0034 0.0117 0.0124
Echinococcus multilocularis glycogen phosphorylase 0.0113 0.0688 0.0688
Echinococcus multilocularis EF HAND 1, calcium binding site 0.005 0.0229 0.0229
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0107 0.0645 0.0645
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0065 0.0343 0.0334
Entamoeba histolytica glycogen phosphorylase, putative 0.0049 0.0223 0.0401
Leishmania major cathepsin L-like protease 0.0344 0.2363 0.2488
Echinococcus granulosus neuronal calcium sensor 0.005 0.0229 0.0229
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0018 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Echinococcus granulosus delta-like protein 1 0.0034 0.0117 0.0117
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0018 0.0018
Loa Loa (eye worm) papain family cysteine protease containing protein 0.008 0.0452 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0151 0.0449
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0452 0.1341
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2363 0.7007
Toxoplasma gondii ABC1 family protein 0.0107 0.0645 0.0686
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0018 0.0019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0018 0.0018
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0332 0.2272 0.2391
Loa Loa (eye worm) hypothetical protein 0.1317 0.9409 1
Brugia malayi MAP kinase sur-1 0.0051 0.024 0.0255
Trichomonas vaginalis penicillin-binding protein, putative 0.0107 0.0645 0.1914
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0173 0.0173
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0107 0.0645 0.0601
Toxoplasma gondii centrin, putative 0.005 0.0229 0.0244
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0107 0.0644 0.0685
Mycobacterium tuberculosis Conserved protein 0.0107 0.0645 0.0601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Brugia malayi hypothetical protein 0.0039 0.0151 0.0161
Entamoeba histolytica calpain large subunit domain III containing protein 0.0232 0.155 0.6353
Echinococcus multilocularis microtubule associated protein 2 0.1398 1 1
Echinococcus granulosus neural cadherin 0.0034 0.0117 0.0117
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0151 0.0161
Loa Loa (eye worm) notch protein 0.0034 0.0117 0.0124
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Echinococcus multilocularis neurogenic locus notch protein 0.0034 0.0117 0.0117
Loa Loa (eye worm) EF hand family protein 0.005 0.0229 0.0244
Plasmodium falciparum importin beta, putative 0.0057 0.0281 0.119
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.005 0.0229 0.0428
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1317 0.9409 0.9409
Echinococcus multilocularis neurogenic locus notch protein 4 0.0034 0.0117 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0151 0.0449
Echinococcus granulosus Glycosyl transferase family 35 0.0113 0.0688 0.0688
Loa Loa (eye worm) hypothetical protein 0.0647 0.4558 0.4844
Toxoplasma gondii exonuclease III APE 0.0039 0.0149 0.0159
Brugia malayi beta-lactamase 0.0107 0.0645 0.0686
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0929 0.6597 0.6597
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.01 0.0592 0.0526
Schistosoma mansoni calpain C (C02 family) 0.0332 0.2272 0.2272
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Toxoplasma gondii hypothetical protein 0.0138 0.087 0.0925
Schistosoma mansoni calpain (C02 family) 0.0332 0.2272 0.2272
Mycobacterium leprae Probable lipase LipE 0.0107 0.0645 0.0522
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Plasmodium vivax unspecified product 0.0187 0.1227 0.5192
Echinococcus granulosus cathepsin b 0.0751 0.5307 0.5307
Trichomonas vaginalis calpain, putative 0.01 0.0592 0.1756
Brugia malayi EGF-like domain containing protein 0.0034 0.0117 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0155 0.0155
Trypanosoma brucei Calpain-like protein 2 0.01 0.0592 0.0526
Trypanosoma cruzi kinesin, putative 0.0232 0.155 0.1621
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0018 0.0019
Toxoplasma gondii calcium-dependent protein kinase 0.0051 0.0238 0.0253
Echinococcus multilocularis calpain 7 (C02 family) 0.0332 0.2272 0.2272
Brugia malayi Cathepsin L-like precursor 0.0237 0.1588 0.1688
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0229 0.0136
Onchocerca volvulus 0.0034 0.0114 0.0121
Plasmodium vivax proteasome subunit beta type-5, putative 0.0084 0.0479 0.2028
Trypanosoma brucei cysteine peptidase, putative 0.01 0.0592 0.0526
Loa Loa (eye worm) hypothetical protein 0.004 0.0162 0.0172
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0173 0.0075
Brugia malayi steroid hormone receptor 0.002 0.0018 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0018 0.0019
Giardia lamblia Cathepsin B precursor 0.008 0.0452 0.1825
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0315 0.0315
Echinococcus multilocularis cathepsin L 0.008 0.0452 0.0452
Brugia malayi prolyl oligopeptidase family protein 0.0138 0.087 0.0925
Schistosoma mansoni laminin gamma-3 chain 0.0034 0.0117 0.0117
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0294 0.0294
Brugia malayi Cathepsin L-like precursor 0.0107 0.0644 0.0685
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.024 0.0713
Entamoeba histolytica cysteine protease, putative 0.0344 0.2363 1
Leishmania major calpain protease-like protein 0.01 0.0592 0.06
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0151 0.0449
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.008 0.0452 0.0481
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0151 0.0161
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Mycobacterium ulcerans hypothetical protein 0.0034 0.0114 0.0033
Giardia lamblia Dipeptidyl-peptidase I precursor 0.008 0.0452 0.1825
Schistosoma mansoni calmodulin related calcium binding protein 0.005 0.0229 0.0229
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.008 0.0452 0.0452
Brugia malayi programmed cell death protein 6 0.005 0.0229 0.0244
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0332 0.2272 0.2391
Echinococcus granulosus cathepsin L cysteine protease 0.0187 0.1227 0.1227
Leishmania major cathepsin L-like protease 0.044 0.3054 0.3224
Schistosoma mansoni hypothetical protein 0.0424 0.2943 0.2943
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0163 0.0163
Echinococcus granulosus acylamino acid releasing enzyme 0.0138 0.087 0.087
Loa Loa (eye worm) proteasome subunit beta type 1 0.0065 0.0343 0.0365
Plasmodium falciparum serine repeat antigen 2 0.008 0.0452 0.1914
Plasmodium falciparum proteasome subunit beta type-5 0.0084 0.0479 0.2028
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0018 0.0018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Entamoeba histolytica prolyl oligopeptidase family protein 0.0138 0.087 0.3304
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0138 0.087 0.0925
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0205 0.0218
Brugia malayi Delta serrate ligand family protein 0.0034 0.0117 0.0124
Echinococcus multilocularis proteasome (prosome, macropain) 0.0084 0.0479 0.0479
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Schistosoma mansoni cathepsin B (C01 family) 0.008 0.0452 0.0452
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.024 0.024
Trichomonas vaginalis glycogen phosphorylase, putative 0.0113 0.0688 0.2039
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0138 0.087 0.0825
Echinococcus multilocularis expressed protein 0.0756 0.5349 0.5349
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0019
Echinococcus multilocularis tissue type plasminogen activator 0.0022 0.003 0.003
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0295 0.0313
Brugia malayi Papain family cysteine protease containing protein 0.008 0.0452 0.0481
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.0155 0.0155
Entamoeba histolytica grainin, putative 0.005 0.0234 0.0451
Trichomonas vaginalis ran, putative 0.0042 0.0173 0.0512
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0205 0.0218
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Loa Loa (eye worm) trypsin family protein 0.0034 0.0114 0.0121
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0084 0.0479 0.0479
Mycobacterium ulcerans beta-lactamase 0.0107 0.0645 0.1525
Loa Loa (eye worm) hypothetical protein 0.0034 0.0114 0.0121
Echinococcus granulosus calumenin 0.005 0.0234 0.0234
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0138 0.087 0.2581
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0766 0.1865
Mycobacterium ulcerans esterase/lipase LipP 0.0107 0.0645 0.1525
Trypanosoma cruzi caltractin, putative 0.005 0.0229 0.0213
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0084 0.0479 0.04
Echinococcus multilocularis transmembrane protease serine 3 0.0034 0.0114 0.0114
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0315 0.0315
Loa Loa (eye worm) TK/ROR protein kinase 0.0022 0.003 0.0032
Entamoeba histolytica cysteine protease, putative 0.008 0.0452 0.1429
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.1227 0.3638
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0018 0.0019
Giardia lamblia Cathepsin L precursor 0.008 0.0452 0.1825
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0205 0.0205
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.005 0.0229 0.0213
Leishmania major cathepsin L-like protease 0.0344 0.2363 0.2488
Brugia malayi cathepsin L-like precursor 0.0237 0.1588 0.1688
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0229 0.068
Plasmodium falciparum cysteine proteinase falcipain 3 0.0344 0.2363 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.0155 0.0155
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2363 0.7007
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.005 0.0229 0.0136
Loa Loa (eye worm) Notch2 0.0034 0.0117 0.0124
Brugia malayi hypothetical protein 0.0242 0.1626 0.1728
Echinococcus multilocularis EF hand domain containing family member A2 0.005 0.0229 0.0229
Echinococcus granulosus caspase 2 0.0058 0.0288 0.0288
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0684 0.4824 0.5661
Trypanosoma brucei prolyl endopeptidase 0.1317 0.9409 1
Brugia malayi Kringle domain containing protein 0.0022 0.003 0.0032
Schistosoma mansoni nuclear hormone receptor 0.002 0.0018 0.0018
Schistosoma mansoni notch 0.0034 0.0117 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0344 0.2363 0.7007
Trichomonas vaginalis calcium binding proteins, putative 0.005 0.0229 0.068
Entamoeba histolytica Ran family GTPase 0.0042 0.0173 0.0174
Mycobacterium ulcerans hypothetical protein 0.0107 0.0645 0.1525
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0065 0.0343 0.0334
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0018 0.0019
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0039 0.0151 0.0151
Brugia malayi EGF-like domain containing protein 0.0034 0.0117 0.0124
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0332 0.2272 0.2391
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0151 0.0151
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0547 0.3836 0.4077
Giardia lamblia Cysteine protease 0.008 0.0452 0.1825
Trypanosoma brucei proteasome subunit beta type-2, putative 0.004 0.0163 0.0065
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0592 0.06
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0332 0.2272 0.2391
Mycobacterium ulcerans lipase LipD 0.0107 0.0645 0.1525
Trypanosoma brucei protein I/6 0.005 0.0229 0.0136
Brugia malayi ecdysteroid receptor 0.002 0.0018 0.0019
Leishmania major hypothetical protein, conserved 0.0107 0.0645 0.0656
Loa Loa (eye worm) hypothetical protein 0.0107 0.0644 0.0685
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0018 0.0018
Trypanosoma brucei protein kinase, putative 0.0051 0.024 0.0148
Brugia malayi EF hand family protein 0.005 0.0234 0.0249
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0929 0.6597 0.6597
Echinococcus multilocularis snurportin 1 0.0606 0.4261 0.4261
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.008 0.0452 0.1341
Schistosoma mansoni hypothetical protein 0.0034 0.0117 0.0117
Onchocerca volvulus 0.0034 0.0117 0.0124
Trypanosoma brucei hypothetical protein, conserved 0.0107 0.0645 0.0583
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0065 0.0343 0.0343
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0149 0.0068
Brugia malayi calpain family protein 1 0.0879 0.6238 0.663
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Onchocerca volvulus Peroxidasin homolog 0.0304 0.2071 0.2201
Onchocerca volvulus 0.002 0.0018 0.0019
Schistosoma mansoni hypothetical protein 0.017 0.1099 0.1099
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0524 0.3663 1
Echinococcus granulosus cysteine protease 0.0187 0.1227 0.1227
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0173 0.0731
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Onchocerca volvulus 0.0049 0.0228 0.0242
Loa Loa (eye worm) cathepsin B 0.0288 0.1954 0.2076
Entamoeba histolytica prolyl oligopeptidase family protein 0.0138 0.087 0.3304
Brugia malayi A-kinase anchor protein 10, precursor 0.0039 0.0151 0.0161
Echinococcus granulosus calpain A 0.0929 0.6602 0.6602
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Plasmodium vivax hypothetical protein, conserved 0.0138 0.087 0.3683
Echinococcus multilocularis cysteine protease 0.0344 0.2363 0.2363
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Schistosoma mansoni neuronal calcium sensor 0.005 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0332 0.2272 0.2391
Giardia lamblia Cathepsin L-like protease 0.008 0.0452 0.1825
Plasmodium vivax vivapain-1 0.0187 0.1227 0.5192
Trypanosoma cruzi cysteine peptidase, putative 0.044 0.3054 0.3224
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0149 0.0127
Loa Loa (eye worm) hypothetical protein 0.0034 0.0114 0.0121
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.024 0.0255
Leishmania major cytochrome p450-like protein 0.0032 0.0102 0.0078
Schistosoma mansoni gamma-secretase subunit aph-1 0.0237 0.1589 0.1589
Echinococcus multilocularis dnaJ subfamily B 0.0424 0.2943 0.2943
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0018 0.0018
Trypanosoma brucei caltractin, putative 0.005 0.0229 0.0136
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.073 0.0776
Loa Loa (eye worm) animal heme peroxidase 0.0304 0.2071 0.2201
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0203 0.0603
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0155 0.0155
Entamoeba histolytica cysteine proteinase 1, putative 0.0187 0.1227 0.4903
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0034 0.0117 0.0124
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0151 0.0151
Brugia malayi Animal haem peroxidase family protein 0.0304 0.2071 0.2201
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.005 0.0229 0.068
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0032
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0084 0.0479 0.1421
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.1626 0.1626
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.005 0.0233 0.014
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0203 0.0185
Plasmodium vivax proteasome subunit beta type-2, putative 0.004 0.0163 0.0691
Loa Loa (eye worm) animal heme peroxidase 0.0304 0.2071 0.2201
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0149 0.0159
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0117 0.0124
Onchocerca volvulus 0.004 0.0162 0.0172
Onchocerca volvulus 0.0034 0.0114 0.0121
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0151 0.0151
Schistosoma mansoni notch 0.0034 0.0119 0.0119
Trypanosoma cruzi cruzipain precursor, putative 0.044 0.3054 0.3224
Echinococcus granulosus calbindin 32 0.005 0.0234 0.0234
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.024 0.0713
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.008 0.0452 0.1341
Onchocerca volvulus 0.0034 0.0117 0.0124
Echinococcus granulosus dnaJ subfamily B 0.0424 0.2943 0.2943
Schistosoma mansoni thyroid hormone receptor 0.002 0.0018 0.0018
Entamoeba histolytica calcium binding family protein 0.005 0.0229 0.0428
Brugia malayi Animal haem peroxidase family protein 0.0304 0.2071 0.2201
Trichomonas vaginalis set domain proteins, putative 0.0483 0.3372 1
Schistosoma mansoni hypothetical protein 0.017 0.1099 0.1099
Brugia malayi Cytochrome P450 family protein 0.0032 0.0102 0.0109
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.008 0.0452 0.1914
Toxoplasma gondii cathepsin B 0.0288 0.1954 0.2076
Trypanosoma cruzi cysteine peptidase, putative 0.044 0.3054 0.3224
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Brugia malayi MH2 domain containing protein 0.0119 0.073 0.0776
Trypanosoma brucei proteasome beta 6 subunit 0.0065 0.0343 0.0259
Brugia malayi EGF-like domain containing protein 0.0034 0.0117 0.0124
Schistosoma mansoni ef hand domain family member A2 0.005 0.0229 0.0229
Onchocerca volvulus Neurogenic locus notch homolog 0.0034 0.0119 0.0126
Giardia lamblia Glycogen phosphorylase 0.0113 0.0688 0.3106
Schistosoma mansoni thyroid hormone receptor 0.002 0.0018 0.0018
Brugia malayi cathepsin Z-like cysteine proteinase 0.008 0.0452 0.0481
Brugia malayi Cytochrome P450 family protein 0.0053 0.0254 0.027
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0751 0.5307 0.5307
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0332 0.2272 0.2391
Loa Loa (eye worm) hypothetical protein 0.0344 0.2363 0.2511
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0161
Brugia malayi Papain family cysteine protease containing protein 0.008 0.0452 0.0481
Schistosoma mansoni microtubule-associated protein tau 0.1398 1 1
Brugia malayi Calmodulin-like protein 0.005 0.0229 0.0244
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0592 0.06
Loa Loa (eye worm) blistered cuticle protein 3 0.0304 0.2071 0.2201
Entamoeba histolytica cysteine protease, putative 0.008 0.0452 0.1429
Loa Loa (eye worm) animal heme peroxidase 0.0304 0.2071 0.2201
Loa Loa (eye worm) animal heme peroxidase 0.0304 0.2071 0.2201
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0138 0.087 0.3304
Mycobacterium tuberculosis Probable hydrolase 0.0107 0.0645 0.0601
Loa Loa (eye worm) hypothetical protein 0.008 0.0452 0.0481
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0173 0.0152
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0018 0.0019
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0102 0.0078
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0173 0.0302
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0228 0.0242
Trypanosoma cruzi hypothetical protein, conserved 0.0107 0.0645 0.0656
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0138 0.087 0.0925
Onchocerca volvulus 0.0153 0.0979 0.104
Echinococcus multilocularis beta LACTamase domain containing family member 0.0107 0.0645 0.0645
Brugia malayi nuclear receptor NHR-88 0.002 0.0018 0.0019
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0107 0.0645 0.0686
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2363 0.7007
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0929 0.6597 0.6597
Loa Loa (eye worm) calpain 0.0332 0.2272 0.2415
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0019
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0086 0.0091
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.024 0.0225
Entamoeba histolytica protein kinase, putative 0.0232 0.1553 0.6368
Onchocerca volvulus 0.003 0.0086 0.0091
Loa Loa (eye worm) hypothetical protein 0.0107 0.0645 0.0686
Brugia malayi hypothetical protein 0.0034 0.0114 0.0121
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0205 0.0205
Onchocerca volvulus 0.0034 0.0114 0.0121
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.005 0.0229 0.0428
Trypanosoma brucei centrin, putative 0.005 0.0229 0.0136
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0117 0.0124
Loa Loa (eye worm) hypothetical protein 0.008 0.0452 0.0481
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.01 0.0592 0.0526
Loa Loa (eye worm) hypothetical protein 0.0034 0.0114 0.0121
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0107 0.0645 0.1525
Trichomonas vaginalis myosin light chain 1, putative 0.005 0.0229 0.068
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.008 0.0452 0.1341
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Echinococcus granulosus enteropeptidase 0.0034 0.0114 0.0114
Echinococcus granulosus slit 2 protein 0.0034 0.0117 0.0117
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Brugia malayi PXA domain containing protein 0.0039 0.0151 0.0161
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0151 0.0151
Schistosoma mansoni hypothetical protein 0.004 0.0162 0.0162
Leishmania major cathepsin L-like protease 0.044 0.3054 0.3224
Entamoeba histolytica calmodulin, putative 0.005 0.0229 0.0428
Trypanosoma cruzi calmodulin, putative 0.005 0.0229 0.0213
Trypanosoma cruzi hypothetical protein, conserved 0.0138 0.087 0.0896
Trypanosoma brucei calpain-like protein, putative 0.0332 0.2272 0.2331
Entamoeba histolytica cysteine proteinase, putative 0.0187 0.1227 0.4903
Onchocerca volvulus 0.0304 0.2071 0.2201
Trypanosoma cruzi 20S proteasome subunit 0.004 0.0163 0.0142
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.008 0.0452 0.1914
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0018 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.008 0.0452 0.1341
Loa Loa (eye worm) hypothetical protein 0.008 0.0452 0.0481
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.008 0.0452 0.1914
Brugia malayi GCC2 and GCC3 family protein 0.0034 0.0117 0.0124
Brugia malayi calcium-binding protein 0.005 0.0229 0.0244
Loa Loa (eye worm) hypothetical protein 0.008 0.0452 0.0481
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0151 0.0151
Trichomonas vaginalis centrin, putative 0.005 0.0229 0.068
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0034 0.0114 0.0114
Echinococcus multilocularis regulator of G protein signaling 0.0039 0.0151 0.0151
Brugia malayi gamma-secretase subunit aph-1 0.0237 0.1589 0.1688
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0751 0.5307 0.5626
Echinococcus granulosus prolyl endopeptidase 0.1317 0.9409 0.9409
Brugia malayi EGF-like domain containing protein 0.0034 0.0117 0.0124
Loa Loa (eye worm) hypothetical protein 0.0034 0.0114 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0018 0.0019
Schistosoma mansoni hypothetical protein 0.01 0.0592 0.0592
Plasmodium falciparum calpain 0.01 0.0592 0.2505
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0084 0.0479 0.1549
Schistosoma mansoni coup transcription factor 0.002 0.0018 0.0018
Echinococcus granulosus calmodulin 0.005 0.0229 0.0229
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0187 0.1227 0.1276
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.008 0.0452 0.1341
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.0766 0.0766
Schistosoma mansoni calpain-7 (C02 family) 0.0332 0.2272 0.2272
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.008 0.0452 0.1914
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.0766 0.0747
Echinococcus granulosus importin subunit beta 1 0.0057 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Trichomonas vaginalis calmodulin, putative 0.005 0.0229 0.068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0018 0.0019
Echinococcus granulosus cathepsin L cysteine proteinase 0.0344 0.2363 0.2363
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.024 0.0255
Leishmania major hypothetical protein, conserved 0.005 0.0229 0.0213
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0187 0.1227 0.1227
Entamoeba histolytica calcium-binding protein, putative 0.005 0.0229 0.0428
Onchocerca volvulus 0.005 0.0233 0.0247
Echinococcus granulosus apoptotic protease activating factor 1 0.004 0.0162 0.0162
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0107 0.0645 0.0645
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0766 0.0766
Loa Loa (eye worm) hypothetical protein 0.0107 0.0645 0.0686
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0344 0.2363 0.2511
Onchocerca volvulus 0.005 0.0229 0.0244
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.008 0.0452 0.1914
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0114 0.0114
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0524 0.3663 0.3874
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0114 0.0114
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.01 0.0592 0.0526
Brugia malayi notch-like transmembrane receptor 0.0034 0.0117 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0344 0.2363 0.7007
Trichomonas vaginalis calmodulin-2, putative 0.005 0.0229 0.068
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0281 0.0281
Plasmodium vivax centrin-1, putative 0.005 0.0229 0.0971
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.008 0.0452 0.1341
Trypanosoma brucei Component of motile flagella 41 0.005 0.0229 0.0136
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0524 0.3663 0.3874
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2363 0.7007
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0138 0.087 0.0825
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Echinococcus multilocularis calmodulin 0.005 0.0229 0.0229
Echinococcus multilocularis protein jagged 1 0.0034 0.0117 0.0117
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0018 0.0019
Echinococcus granulosus calpain A 0.0332 0.2272 0.2272
Mycobacterium tuberculosis Conserved protein 0.0107 0.0645 0.0601
Entamoeba histolytica hypothetical protein 0.008 0.0452 0.1429
Brugia malayi Cathepsin L-like cysteine proteinase 0.0237 0.1588 0.1688
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0161
Trypanosoma brucei antigen, putative 0.0332 0.2272 0.2331
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Brugia malayi Trypsin family protein 0.0034 0.0114 0.0121
Echinococcus granulosus EF hand domain containing family member A2 0.005 0.0234 0.0234
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0114 0.0114
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.008 0.0452 0.0452
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0022 0.003 0.0126
Trypanosoma cruzi cysteine protease, putative 0.0187 0.1227 0.1276
Echinococcus granulosus protein jagged 2 0.0034 0.0117 0.0117
Onchocerca volvulus 0.0107 0.0645 0.0686
Echinococcus multilocularis notch 0.0034 0.0117 0.0117
Giardia lamblia Cathepsin L precursor 0.008 0.0452 0.1825
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.005 0.0229 0.0213
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0018 0.0018
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.0645 0.1914
Trypanosoma cruzi cysteine peptidase, putative 0.0187 0.1227 0.1276
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0114 0.0114
Brugia malayi Papain family cysteine protease containing protein 0.0187 0.1227 0.1304
Trypanosoma brucei calpain-like protein, putative 0.0332 0.2272 0.2331
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0134 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Echinococcus granulosus snurportin 1 0.0606 0.4261 0.4261
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.008 0.0452 0.1825
Entamoeba histolytica cysteine proteinase, putative 0.0344 0.2363 1
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0138 0.087 0.087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Trypanosoma cruzi hypothetical protein, conserved 0.0107 0.0645 0.0656
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.005 0.0229 0.0229
Echinococcus multilocularis geminin 0.017 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.008 0.0452 0.0481
Brugia malayi Animal haem peroxidase family protein 0.0304 0.2071 0.2201
Entamoeba histolytica cysteine protease, putative 0.008 0.0452 0.1429
Echinococcus granulosus protein jagged 1 0.0034 0.0117 0.0117
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0018 0.0018
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Entamoeba histolytica hypothetical protein 0.0039 0.0151 0.0078
Trypanosoma cruzi major cysteine proteinase, putative 0.008 0.0452 0.0451
Trypanosoma brucei centrin, putative 0.005 0.0229 0.0136
Trypanosoma brucei calmodulin, putative 0.005 0.0234 0.0142
Loa Loa (eye worm) calpain 5 0.0232 0.155 0.1647
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Brugia malayi Peroxidasin 0.0304 0.2071 0.2201
Trypanosoma cruzi oligopeptidase b 0.0524 0.3663 0.3874
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0034 0.0114 0.0121
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Giardia lamblia Cathepsin B precursor 0.0288 0.1954 1
Trypanosoma cruzi centrin, putative 0.005 0.0229 0.0213
Trypanosoma cruzi cysteine peptidase, putative 0.0344 0.2363 0.2488
Trichomonas vaginalis calpain, putative 0.01 0.0592 0.1756
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0592 0.1756
Brugia malayi Cathepsin L-like precursor 0.0344 0.2363 0.2511
Trypanosoma cruzi cysteine peptidase, putative 0.044 0.3054 0.3224
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0151 0.0449
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Trypanosoma cruzi I/6 autoantigen, putative 0.005 0.0229 0.0213
Onchocerca volvulus 0.0547 0.3836 0.4077
Giardia lamblia Cathepsin B precursor 0.0288 0.1954 1
Brugia malayi Serotonin receptor 0.0463 0.3225 0.3428
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0018 0.0018
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0138 0.087 0.3304
Trypanosoma cruzi calmodulin, putative 0.005 0.0229 0.0213
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0315 0.0315
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0065 0.0343 0.1453
Loa Loa (eye worm) fibroinase 0.0344 0.2363 0.2511
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0149 0.0131
Schistosoma mansoni centrin 0.005 0.0229 0.0229
Echinococcus multilocularis enteropeptidase 0.0034 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.008 0.0452 0.1341
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0151 0.0151
Trichomonas vaginalis calmodulin, putative 0.005 0.0229 0.068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2363 0.7007
Echinococcus granulosus protein jagged 1 0.0034 0.0117 0.0117
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.008 0.0452 0.0452
Plasmodium vivax serine-repeat antigen (SERA), putative 0.008 0.0452 0.1914
Giardia lamblia Cathepsin L precursor 0.008 0.0452 0.1825
Trypanosoma cruzi conserved protein 0.01 0.0592 0.06
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.0526
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Trichomonas vaginalis calmodulin, putative 0.005 0.0229 0.068
Brugia malayi Cathepsin L-like precursor 0.0344 0.2363 0.2511
Schistosoma mansoni neuronal calcium sensor 0.005 0.0229 0.0229
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0524 0.3663 0.4255
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0151 0.0151
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0592 0.1756
Plasmodium falciparum cysteine repeat modular protein 1 0.0022 0.003 0.0126
Brugia malayi hypothetical protein 0.0153 0.0979 0.104
Entamoeba histolytica glycogen phosphorylase, putative 0.0113 0.0688 0.2484
Brugia malayi cathepsin L precursor 0.008 0.0452 0.0481
Echinococcus multilocularis EF hand domain containing family member A2 0.005 0.0234 0.0234
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2363 0.7007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Onchocerca volvulus 0.0304 0.2071 0.2201
Leishmania major calmodulin, putative 0.005 0.0229 0.0213
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Entamoeba histolytica cysteine proteinase, putative 0.0344 0.2363 1
Plasmodium falciparum centrin-1 0.005 0.0229 0.0971
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0065 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0161
Leishmania major calcineurin B subunit, putative 0.005 0.0229 0.0213
Echinococcus granulosus peroxidasin 0.0304 0.2071 0.2071
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0592 0.1756
Plasmodium vivax hypothetical protein, conserved 0.005 0.0234 0.0992
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0018 0.0019
Onchocerca volvulus 0.0304 0.2071 0.2201
Echinococcus granulosus fibropellin Ia 0.0034 0.0117 0.0117
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0344 0.0344
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0149 0.0631
Echinococcus multilocularis cathepsin L 0.0187 0.1227 0.1227
Echinococcus granulosus Dipeptidyl peptidase 9 0.0138 0.087 0.087
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Entamoeba histolytica hypothetical protein 0.0046 0.0203 0.0312
Onchocerca volvulus Chorion peroxidase homolog 0.0304 0.2071 0.2201
Brugia malayi Trypsin-like protease protein 5 0.0034 0.0114 0.0121
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.073 0.0776
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0288 0.1954 0.1954
Schistosoma mansoni hypothetical protein 0.0034 0.0117 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.0526
Onchocerca volvulus 0.0484 0.3374 0.3586
Toxoplasma gondii EGF family domain-containing protein 0.0034 0.0117 0.0124
Schistosoma mansoni glycogen phosphorylase 0.0049 0.0223 0.0223
Brugia malayi calpain 5 0.0232 0.155 0.1647
Brugia malayi Cathepsin L-like precursor 0.0344 0.2363 0.2511
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0149 0.0149
Plasmodium vivax vivapain-2 0.0344 0.2363 1
Schistosoma mansoni hypothetical protein 0.0034 0.0117 0.0117
Brugia malayi cathepsin Z-like cysteine proteinase 0.008 0.0452 0.0481
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0138 0.087 0.0925
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0018 0.0018
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.024 0.0148
Brugia malayi prolyl oligopeptidase family protein 0.1317 0.9409 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0645 0.0686
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0592 0.1756
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0018 0.0019
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0151 0.0151
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0333 0.2279 0.2398
Trypanosoma cruzi cruzipain precursor, putative 0.0107 0.0644 0.0655
Brugia malayi Cathepsin L-like precursor 0.0344 0.2363 0.2511
Onchocerca volvulus Slit protein homolog 0.0034 0.0117 0.0124
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Schistosoma mansoni hypothetical protein 0.0606 0.4261 0.4261
Onchocerca volvulus 0.0034 0.0114 0.0121
Echinococcus multilocularis calmodulin 0.005 0.0229 0.0229
Schistosoma mansoni caspase-7 (C14 family) 0.0058 0.0288 0.0288
Onchocerca volvulus 0.008 0.0452 0.0481
Schistosoma mansoni reticulocalbin 0.005 0.0229 0.0229
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0332 0.2272 0.2391
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0138 0.087 0.087
Trypanosoma brucei calpain-like protein, putative 0.0332 0.2272 0.2331
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0592 0.1756
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0117 0.0124
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0187 0.1227 0.1227
Schistosoma mansoni calpain-7 (C02 family) 0.0332 0.2272 0.2272
Trypanosoma brucei cysteine peptidase C (CPC) 0.0288 0.1954 0.1989
Loa Loa (eye worm) calmodulin-like protein 0.005 0.0229 0.0244
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.008 0.0452 0.1341
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0034 0.0114 0.0114
Toxoplasma gondii cathepsin CPC2 0.008 0.0452 0.0481
Plasmodium falciparum serine repeat antigen 4 0.008 0.0452 0.1914
Onchocerca volvulus 0.0344 0.2363 0.2511
Schistosoma mansoni calmodulin 0.005 0.0229 0.0229
Brugia malayi calpain family protein 1 0.0879 0.6238 0.663
Echinococcus multilocularis Regulator of G protein signaling 20 0.0039 0.0151 0.0151
Brugia malayi Cathepsin L-like precursor 0.0344 0.2363 0.2511
Schistosoma mansoni importin beta-1 0.0057 0.0281 0.0281
Trypanosoma brucei calpain-like protein, putative 0.0332 0.2272 0.2331
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.005 0.0229 0.0229
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0524 0.3663 0.3826
Echinococcus granulosus cathepsin l cysteine peptidase 0.0344 0.2363 0.2363
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.008 0.0452 0.1341
Schistosoma mansoni hypothetical protein 0.0034 0.0114 0.0114
Plasmodium vivax vivapain-3 0.0187 0.1227 0.5192
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.008 0.0452 0.0452
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.008 0.0452 0.1341
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Plasmodium vivax serine-repeat antigen (SERA) 0.008 0.0452 0.1914
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0281 0.0192
Trypanosoma brucei calmodulin, putative 0.005 0.0229 0.0136
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0151 0.0151
Onchocerca volvulus 0.0022 0.003 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0237 0.1588 0.1688
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0254 0.027
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0161
Loa Loa (eye worm) hypothetical protein 0.0138 0.087 0.0925
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0163 0.0484
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0107 0.0645 0.0601
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0065 0.0343 0.0365
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0049 0.0223 0.034
Onchocerca volvulus Peroxidasin homolog 0.0304 0.2071 0.2201
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0138 0.087 0.087
Schistosoma mansoni glycogen phosphorylase 0.0113 0.0688 0.0688
Leishmania major calpain family cysteine protease-like protein 0.01 0.0592 0.06
Onchocerca volvulus 0.0034 0.0117 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0151 0.0449
Trypanosoma brucei Calpain-like protein 1.1 0.01 0.0592 0.0526
Entamoeba histolytica cysteine proteinase, putative 0.0237 0.1588 0.6525
Echinococcus multilocularis neurogenic locus protein delta 0.0034 0.0117 0.0117
Trypanosoma cruzi cysteine proteinase, putative 0.0187 0.1227 0.1276
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0237 0.1588 0.471
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0281 0.0192
Echinococcus multilocularis calpain 0.0332 0.2272 0.2272
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.1227 0.3638
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0084 0.0479 0.0509
Giardia lamblia Cathepsin B precursor 0.008 0.0452 0.1825
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0592 0.1756
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0018 0.0019
Brugia malayi Pre-SET motif family protein 0.0425 0.2947 0.3133
Trichomonas vaginalis calcineurin B subunit, putative 0.005 0.0229 0.068
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0332 0.2272 0.2391
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.1626 0.1626
Echinococcus multilocularis prolyl endopeptidase 0.1317 0.9409 0.9409
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0138 0.087 0.0896
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0151 0.0151
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0134 0.0134
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0149 0.0127
Brugia malayi hypothetical protein 0.0304 0.2071 0.2201
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Loa Loa (eye worm) hypothetical protein 0.0107 0.0645 0.0686
Onchocerca volvulus Cathepsin L homolog 0.0344 0.2363 0.2511
Giardia lamblia Cysteine protease 0.008 0.0452 0.1825
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0425 0.2947 0.3133
Brugia malayi Pre-SET motif family protein 0.0061 0.0315 0.0335
Loa Loa (eye worm) hypothetical protein 0.0034 0.0114 0.0121
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0149 0.005
Giardia lamblia Hypothetical protein 0.008 0.0452 0.1825
Trypanosoma cruzi centrin, putative 0.005 0.0229 0.0213
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0237 0.1589 0.1688
Plasmodium falciparum serine repeat antigen 6 0.008 0.0452 0.1914
Loa Loa (eye worm) hypothetical protein 0.005 0.0233 0.0247
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.008 0.0452 0.1914
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0149 0.0159
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Mycobacterium tuberculosis Probable lipase LipD 0.0107 0.0645 0.0601
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0018 0.0018
Brugia malayi cathepsin L-like cysteine proteinase 0.008 0.0452 0.0481
Onchocerca volvulus Dual oxidase homolog 0.0304 0.2071 0.2201
Onchocerca volvulus 0.0034 0.0117 0.0124
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0766 0.1865
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0187 0.1227 0.1227
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.01 0.0592 0.0629
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0203 0.0603
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.008 0.0452 0.0452
Schistosoma mansoni peroxidasin 0.0304 0.2071 0.2071
Loa Loa (eye worm) calpain family protein 1 0.0647 0.4558 0.4844
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0102 0.0109
Trypanosoma brucei kinesin, putative 0.0232 0.155 0.1555
Onchocerca volvulus Peroxidase homolog 0.0304 0.2071 0.2201
Onchocerca volvulus 0.0061 0.0315 0.0335
Echinococcus multilocularis programmed cell death protein 0.005 0.0229 0.0229
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0332 0.2272 0.2391
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.005 0.0233 0.0216
Echinococcus granulosus cathepsin l1 0.0237 0.1588 0.1588
Echinococcus granulosus gamma secretase subunit aph 1 0.0237 0.1589 0.1589
Toxoplasma gondii kringle domain-containing protein 0.0022 0.003 0.0032
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0018 0.0018
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0592 0.06
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.004 0.0163 0.0163
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0173 0.0183
Loa Loa (eye worm) prolyl oligopeptidase 0.0138 0.087 0.0925
Schistosoma mansoni notch 0.0034 0.0117 0.0117
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.024 0.0671
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.005 0.0234 0.0218
Brugia malayi calpain 5 0.01 0.0592 0.0629
Brugia malayi Trypsin family protein 0.0034 0.0114 0.0121
Schistosoma mansoni hypothetical protein 0.0022 0.003 0.003
Onchocerca volvulus 0.0034 0.0117 0.0124
Loa Loa (eye worm) hypothetical protein 0.0058 0.0288 0.0306
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0344 0.2363 0.2363
Onchocerca volvulus 0.0107 0.0645 0.0686
Echinococcus multilocularis Glycosyl transferase, family 35 0.0113 0.0688 0.0688
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0163 0.0163
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.005 0.0229 0.0213
Brugia malayi Papain family cysteine protease containing protein 0.0344 0.2363 0.2511
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0151 0.0151
Echinococcus multilocularis centrin 2 0.005 0.0229 0.0229
Echinococcus multilocularis tumor protein p63 0.0342 0.235 0.235
Onchocerca volvulus Cathepsin L homolog 0.0344 0.2363 0.2511
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0084 0.0479 0.0479
Trichomonas vaginalis calmodulin, putative 0.005 0.0229 0.068
Leishmania major oligopeptidase b 0.0524 0.3663 0.3874
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Plasmodium vivax serine-repeat antigen (SERA) 0.008 0.0452 0.1914
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.01 0.0592 0.06
Schistosoma mansoni cathepsin S (C01 family) 0.008 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Echinococcus multilocularis caspase 2 0.0058 0.0288 0.0288
Loa Loa (eye worm) prolyl oligopeptidase 0.0138 0.087 0.0925
Onchocerca volvulus 0.0237 0.1588 0.1688
Trichomonas vaginalis calmodulin, putative 0.005 0.0229 0.068
Trypanosoma brucei Calpain-like protein 1.2 0.01 0.0592 0.0526
Trichomonas vaginalis centrin, putative 0.005 0.0229 0.068
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0332 0.2272 0.2391
Schistosoma mansoni ap endonuclease 0.0039 0.0149 0.0149
Echinococcus multilocularis neurogenic locus protein delta 0.0034 0.0117 0.0117
Giardia lamblia Hypothetical protein 0.005 0.0234 0.0639
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.008 0.0452 0.1341
Loa Loa (eye worm) hypothetical protein 0.0107 0.0645 0.0686
Schistosoma mansoni reticulocalbin 0.005 0.0234 0.0234
Echinococcus multilocularis protein jagged 2 0.0034 0.0117 0.0117
Leishmania major phospholipase c-like protein 0.005 0.0229 0.0213
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.024 0.0225
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.008 0.0452 0.0452
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.024 0.024
Onchocerca volvulus Peroxidase homolog 0.0304 0.2071 0.2201
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0084 0.0479 0.0479
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0034 0.0117 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0019
Giardia lamblia Cathepsin L precursor 0.008 0.0452 0.1825
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0161
Brugia malayi Trypsin family protein 0.0034 0.0114 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0018 0.0019
Brugia malayi Cadherin domain containing protein 0.0034 0.0117 0.0124
Brugia malayi Papain family cysteine protease containing protein 0.008 0.0452 0.0481
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.005 0.0233 0.0216
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0149 0.0149
Trypanosoma brucei Aph-1 protein, putative 0.0092 0.054 0.047
Leishmania major centrin, putative 0.005 0.0229 0.0213
Echinococcus granulosus neurogenic locus notch protein 0.0034 0.0117 0.0117
Echinococcus granulosus transmembrane protease serine 3 0.0034 0.0114 0.0114
Entamoeba histolytica calpain family cysteine protease, putative 0.01 0.0592 0.2055
Echinococcus granulosus glycogen phosphorylase 0.0113 0.0688 0.0688
Giardia lamblia Alanyl dipeptidyl peptidase 0.0138 0.087 0.4101
Brugia malayi proteasome subunit beta type 2 0.004 0.0163 0.0173
Schistosoma mansoni hypothetical protein 0.0036 0.0134 0.0134
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0281 0.0299
Mycobacterium tuberculosis Probable lipase LipE 0.0107 0.0645 0.0601
Entamoeba histolytica hypothetical protein 0.0039 0.0151 0.0078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0161
Echinococcus multilocularis cathepsin b 0.0751 0.5307 0.5307
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0151 0.0151
Entamoeba histolytica cysteine protease, putative 0.0187 0.1227 0.4903
Onchocerca volvulus 0.005 0.0229 0.0244
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0288 0.1954 0.2051
Onchocerca volvulus 0.0344 0.2363 0.2511
Echinococcus granulosus EF HAND 1 calcium binding site 0.005 0.0229 0.0229
Echinococcus granulosus neurocalcin 0.005 0.0229 0.0229
Echinococcus multilocularis Mastin 0.0034 0.0114 0.0114
Plasmodium falciparum serine repeat antigen 8 0.008 0.0452 0.1914
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0315 0.0315
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0138 0.087 0.087
Toxoplasma gondii EFHC1, putative 0.005 0.0229 0.0244
Plasmodium falciparum serine repeat antigen 9 0.008 0.0452 0.1914
Plasmodium falciparum serine repeat antigen 3 0.008 0.0452 0.1914
Toxoplasma gondii calmodulin CAM1 0.005 0.0234 0.0249
Loa Loa (eye worm) ctsf protein 0.0344 0.2363 0.2511
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0018 0.0018
Trypanosoma brucei calpain, putative 0.01 0.0592 0.0526
Giardia lamblia Dipeptidyl-peptidase I precursor 0.008 0.0452 0.1825
Leishmania major calmodulin-like protein 0.005 0.0229 0.0213
Echinococcus multilocularis neurocalcin 0.005 0.0229 0.0229
Schistosoma mansoni hypothetical protein 0.0034 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0879 0.6238 0.663
Giardia lamblia Cathepsin B precursor 0.008 0.0452 0.1825
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.008 0.0452 0.1341
Mycobacterium tuberculosis Probable esterase LipL 0.0107 0.0645 0.0601
Brugia malayi prolyl oligopeptidase family protein 0.0138 0.087 0.0925
Schistosoma mansoni neuronal calcium sensor 0.005 0.0229 0.0229
Brugia malayi RNA, U transporter 1 0.0161 0.104 0.1105
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0344 0.2363 0.2511
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0205 0.0205
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1179 0.8408 1
Brugia malayi regulator of G-protein signaling egl-10 0.0039 0.0151 0.0161
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0102 0.0109
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0018 0.0018
Giardia lamblia Cathepsin B precursor 0.008 0.0452 0.1825
Trypanosoma cruzi prolyl endopeptidase 0.1317 0.9409 1
Schistosoma mansoni hypothetical protein 0.0034 0.0114 0.0114
Schistosoma mansoni notch 0.0034 0.0117 0.0117
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.008 0.0452 0.1914
Schistosoma mansoni mitochondrial solute carrier 0.005 0.0229 0.0229
Trichomonas vaginalis calmodulin, putative 0.005 0.0234 0.0695
Echinococcus multilocularis glycoprotein Antigen 5 0.0034 0.0114 0.0114
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0018 0.0018
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0163 0.0484
Giardia lamblia Cathepsin B precursor 0.008 0.0452 0.1825
Schistosoma mansoni cathepsin s 0.0107 0.0644 0.0644
Giardia lamblia Cysteine protease 0.008 0.0452 0.1825
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0018 0.0018
Entamoeba histolytica hypothetical protein, conserved 0.005 0.0234 0.0451
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.008 0.0452 0.1341
Brugia malayi beta-lactamase family protein 0.0107 0.0645 0.0686
Toxoplasma gondii proteasome subunit beta type, putative 0.0084 0.0479 0.0509
Toxoplasma gondii cathepsin CPL 0.0344 0.2363 0.2511
Loa Loa (eye worm) hypothetical protein 0.008 0.0452 0.0481
Loa Loa (eye worm) proteasome subunit beta type 2 0.004 0.0163 0.0173
Loa Loa (eye worm) hypothetical protein 0.0237 0.1588 0.1688
Brugia malayi beta-lactamase family protein 0.0107 0.0645 0.0686
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.024 0.0225
Schistosoma mansoni cpg binding protein 0.0031 0.0098 0.0098
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Echinococcus multilocularis neuronal calcium sensor 0.005 0.0229 0.0229
Schistosoma mansoni cathepsin C 0.008 0.0452 0.0452
Toxoplasma gondii EF hand domain-containing protein 0.005 0.0229 0.0244
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.008 0.0452 0.1914
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Loa Loa (eye worm) hypothetical protein 0.0057 0.0281 0.0299
Plasmodium falciparum proteasome subunit beta type-2, putative 0.004 0.0163 0.0691
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.004 0.0163 0.0131
Trypanosoma brucei centrin-3 0.005 0.0229 0.0136
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0149 0.0442
Onchocerca volvulus Cell death protein 3 homolog 0.0058 0.0288 0.0306
Leishmania major kinesin, putative 0.0232 0.155 0.1621
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0151 0.0151
Plasmodium falciparum cysteine proteinase falcipain 1 0.0187 0.1227 0.5192
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0344 0.2363 1
Brugia malayi Animal haem peroxidase family protein 0.0304 0.2071 0.2201
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0138 0.087 0.0896
Leishmania major cysteine peptidase A (CPA) 0.0344 0.2363 0.2488
Trypanosoma brucei prolyl oligopeptidase, putative 0.0524 0.3663 0.3826
Schistosoma mansoni hypothetical protein 0.005 0.0229 0.0229
Echinococcus multilocularis cathepsin L cysteine protease 0.0344 0.2363 0.2363
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0114 0.0114
Plasmodium falciparum serine repeat antigen 7 0.008 0.0452 0.1914
Brugia malayi calpain 7 0.0332 0.2272 0.2415
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0018 0.0018
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0039 0.0151 0.0151
Echinococcus multilocularis gamma secretase subunit aph 1 0.0237 0.1589 0.1589
Echinococcus granulosus cathepsin L 0.0187 0.1227 0.1227
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.008 0.0452 0.1341
Entamoeba histolytica glycogen phosphorylase, putative 0.0113 0.0688 0.2484
Entamoeba histolytica grainin 2 0.005 0.0229 0.0428
Onchocerca volvulus 0.0107 0.0645 0.0686
Schistosoma mansoni hypothetical protein 0.0034 0.0117 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0187 0.1227 0.1208
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.024 0.024
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0766 0.0766
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0592 0.06
Schistosoma mansoni hypothetical protein 0.0049 0.0228 0.0228
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0065 0.0343 0.0343
Brugia malayi nuclear hormone receptor 0.002 0.0018 0.0019
Echinococcus multilocularis peroxidasin 0.0304 0.2071 0.2071
Plasmodium vivax serine-repeat antigen (SERA), putative 0.008 0.0452 0.1914
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0019
Schistosoma mansoni cathepsin F (C01 family) 0.0344 0.2363 0.2363
Entamoeba histolytica cysteine proteinase, putative 0.0187 0.1227 0.4903
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0524 0.3663 0.3874
Plasmodium vivax hypothetical protein, conserved 0.0107 0.0645 0.2731
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0315 0.0315
Trypanosoma brucei hypothetical protein 0.01 0.0592 0.0526
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0237 0.1588 0.471
Giardia lamblia Proteasome subunit beta type 2 0.004 0.0163 0.0251
Loa Loa (eye worm) hypothetical protein 0.01 0.0592 0.0629
Echinococcus granulosus beta LACTamase domain containing family member 0.0107 0.0645 0.0645
Toxoplasma gondii proteasome subunit beta type 2, putative 0.004 0.0163 0.0173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0018 0.0019
Brugia malayi prolyl oligopeptidase family protein 0.0138 0.087 0.0925
Trypanosoma cruzi calpain cysteine peptidase, putative 0.01 0.0592 0.06
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0065 0.0343 0.0939
Echinococcus granulosus cpg binding protein 0.0031 0.0098 0.0098
Echinococcus granulosus glycogen phosphorylase 0.0113 0.0688 0.0688
Loa Loa (eye worm) hypothetical protein 0.005 0.0229 0.0244
Chlamydia trachomatis glycogen phosphorylase 0.0113 0.0688 0.5
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0114 0.0114
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0332 0.2272 0.2391
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0065 0.0343 0.1018
Brugia malayi regulator of G-protein signaling rgs-7 0.0039 0.0151 0.0161
Leishmania major proteasome beta 2 subunit, putative 0.004 0.0163 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0237 0.1588 0.1688
Giardia lamblia Cathepsin B precursor 0.0288 0.1954 1
Schistosoma mansoni rab 0.005 0.0229 0.0229
Entamoeba histolytica prolyl oligopeptidase family protein 0.0138 0.087 0.3304
Echinococcus multilocularis fibropellin Ia 0.0034 0.0117 0.0117
Echinococcus granulosus tissue type plasminogen activator 0.0022 0.003 0.003
Trichomonas vaginalis glycogen phosphorylase, putative 0.0113 0.0688 0.2039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0117 0.0124
Echinococcus multilocularis fat cadherin tumor suppressor 0.0034 0.0117 0.0117
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.008 0.0452 0.0452
Onchocerca volvulus Cathepsin L homolog 0.008 0.0452 0.0481
Echinococcus granulosus expressed protein 0.0756 0.5349 0.5349
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0452 0.1341
Schistosoma mansoni ran 0.0042 0.0173 0.0173
Entamoeba histolytica glycogenphosphorylase, putative 0.0049 0.0223 0.0401
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0766 0.1865
Toxoplasma gondii cathepsin CPC1 0.008 0.0452 0.0481
Mycobacterium tuberculosis Probable peptidase 0.0524 0.3663 0.4255
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.0766 0.0815
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.008 0.0452 0.1914
Loa Loa (eye worm) hypothetical protein 0.0107 0.0645 0.0686
Echinococcus granulosus neurogenic locus notch protein 0.0034 0.0117 0.0117
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.024 0.0225
Echinococcus granulosus EF hand domain containing family member A2 0.005 0.0229 0.0229
Mycobacterium tuberculosis Conserved protein 0.0107 0.0645 0.0601
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0102 0.0078
Echinococcus multilocularis calbindin 32 0.005 0.0234 0.0234
Entamoeba histolytica papain family cysteine protease domain containing protein 0.008 0.0452 0.1429
Echinococcus granulosus sarcoplasmic calcium binding protein 0.005 0.0229 0.0229
Trichomonas vaginalis calcium binding protein, putative 0.005 0.0229 0.068
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0751 0.5307 0.5307
Trypanosoma cruzi kinesin, putative 0.0232 0.155 0.1621
Giardia lamblia Hypothetical protein 0.008 0.0452 0.1825
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0018 0.0018
Trichomonas vaginalis esterase, putative 0.0107 0.0645 0.1914
Echinococcus multilocularis apoptotic protease activating factor 1 0.004 0.0162 0.0162
Echinococcus granulosus cathepsin l1 0.0344 0.2363 0.2363
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.044 0.3054 0.3171
Entamoeba histolytica papain family cysteine protease domain containing protein 0.008 0.0452 0.1429
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0173 0.0731
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0084 0.0479 0.0405
Brugia malayi Importin beta-1 subunit 0.0057 0.0281 0.0299
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0107 0.0645 0.0686
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0332 0.2272 0.2331
Schistosoma mansoni cpg binding protein 0.0031 0.0098 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0151 0.0449
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0149 0.0127
Echinococcus multilocularis calpain A 0.0929 0.6602 0.6602
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0114 0.0114
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0233 0.0233
Brugia malayi Cell death protein 3 precursor 0.0058 0.0288 0.0306
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.005 0.0229 0.068
Loa Loa (eye worm) hypothetical protein 0.0107 0.0644 0.0685
Trypanosoma cruzi Aph-1 protein, putative 0.0092 0.054 0.0544
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.008 0.0452 0.1341
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2363 0.7007
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0138 0.087 0.0825
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0592 0.06
Trypanosoma cruzi Aph-1 protein, putative 0.0092 0.054 0.0544
Leishmania major calmodulin, putative 0.005 0.0229 0.0213
Brugia malayi hypothetical protein 0.0518 0.3619 0.3846
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.0645 0.1914
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0039 0.0155 0.0164
Brugia malayi cahepsin L-like non-peptiedase homolog 0.008 0.0452 0.0481
Trichomonas vaginalis penicillin-binding protein, putative 0.0107 0.0645 0.1914
Leishmania major importin beta-1 subunit, putative 0.0046 0.0203 0.0185
Echinococcus multilocularis slit 2 protein 0.0034 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0304 0.2071 0.2201
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2363 0.7007
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0149 0.5
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0018 0.0019
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0751 0.5307 0.5307
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0751 0.5307 0.5307
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.008 0.0452 0.1914
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0134 0.0134
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0034 0.0114 0.0114
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0151 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0288 0.1954 0.5794
Trypanosoma brucei oligopeptidase b 0.0524 0.3663 0.3826
Echinococcus multilocularis hypothetical protein 0.0332 0.2272 0.2272
Brugia malayi calpain D 0.01 0.0592 0.0629
Onchocerca volvulus Cathepsin F homolog 0.0344 0.2363 0.2511
Entamoeba histolytica hypothetical protein 0.0039 0.0151 0.0078
Mycobacterium ulcerans hydrolase/amidase 0.0271 0.1834 0.4862
Loa Loa (eye worm) hypothetical protein 0.0779 0.5516 0.5862
Brugia malayi Papain family cysteine protease containing protein 0.0187 0.1227 0.1304
Onchocerca volvulus 0.0344 0.2363 0.2511
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0065 0.0343 0.0334
Loa Loa (eye worm) calpain D 0.01 0.0592 0.0629
Echinococcus multilocularis calpain 5 0.0332 0.2272 0.2272

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 45 nM Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assay ChEMBL. 21924902

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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