Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | PHD-finger family protein | 0.0015 | 0.0026 | 0.0031 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0025 | 0.0088 | 0.0077 |
Schistosoma mansoni | zinc finger protein | 0.0042 | 0.0186 | 0.0219 |
Echinococcus granulosus | geminin | 0.0347 | 0.2004 | 0.2337 |
Brugia malayi | Cell division protein ftsZ | 0.0141 | 0.078 | 0.0919 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0067 | 0.0336 | 0.0957 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0036 | 0.0154 | 0.0132 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0049 | 0.0227 | 0.0205 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.0227 | 0.0205 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.004 | 0.0175 | 0.0206 |
Plasmodium falciparum | DNA gyrase subunit A | 0.0607 | 0.3551 | 0.3549 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0014 | 0.0023 | 0.0004 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0063 | 0.0314 | 0.037 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0023 | 0.0001 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0599 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0812 | 0.0959 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.0111 | 0.0105 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0139 | 0.0765 | 0.4467 |
Onchocerca volvulus | Alhambra homolog | 0.0028 | 0.0107 | 0.065 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.17 | 0.2006 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0103 | 0.0553 | 0.0531 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0014 | 0.0023 | 0.0001 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0137 | 0.0136 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0169 | 0.0446 |
Brugia malayi | jmjC domain containing protein | 0.004 | 0.0175 | 0.0206 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0023 | 0.0001 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0049 | 0.0227 | 0.0205 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.0377 | 0.0444 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0067 | 0.0336 | 0.1253 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0115 | 0.0093 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0036 | 0.0154 | 0.0181 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0041 | 0.0184 | 0.0646 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.0111 | 0.0131 |
Mycobacterium ulcerans | oxidoreductase | 0.0114 | 0.062 | 0.0599 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0184 | 0.0646 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0014 | 0.0022 | 0.0019 |
Toxoplasma gondii | DNA gyrase/topoisomerase IV, A subunit domain-containing protein | 0.0607 | 0.3551 | 0.3537 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0063 | 0.0314 | 0.0889 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.181 | 0.1792 |
Schistosoma mansoni | lamin | 0.0029 | 0.0111 | 0.0131 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0065 | 0.0323 | 0.0379 |
Trypanosoma brucei | pteridine reductase 1 | 0.0114 | 0.062 | 0.3593 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0063 | 0.0314 | 0.0369 |
Schistosoma mansoni | tyrosine kinase | 0.0543 | 0.3169 | 0.3728 |
Schistosoma mansoni | protein kinase | 0.1436 | 0.8486 | 0.9982 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.0111 | 0.0105 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0093 | 0.0491 | 0.048 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0023 | 0.0005 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0137 | 0.0136 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0227 | 0.1233 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0014 | 0.0023 | 0.002 |
Chlamydia trachomatis | DNA gyrase subunit A | 0.0063 | 0.0314 | 0.0292 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0074 | 0.0376 | 0.0418 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium ulcerans | hypothetical protein | 0.0155 | 0.0858 | 0.0838 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 0.0491 | 0.0553 |
Chlamydia trachomatis | oxoacy-ACP reductase | 0.0114 | 0.062 | 0.0599 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0114 | 0.062 | 0.3593 |
Onchocerca volvulus | 0.0029 | 0.0111 | 0.0682 | |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0014 | 0.0023 | 0.0012 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.181 | 0.1792 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0111 | 0.0131 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.181 | 0.1792 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0314 | 0.181 | 0.5471 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0154 | 0.0182 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0063 | 0.0314 | 0.1164 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0153 | 0.085 | 0.1001 |
Wolbachia endosymbiont of Brugia malayi | parvulin-like peptidyl-prolyl isomerase, PPID | 0.0021 | 0.0062 | 0.004 |
Treponema pallidum | DNA gyrase, subunit A (gyrA) | 0.0607 | 0.3551 | 1 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0089 | 0.0471 | 0.053 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0063 | 0.0314 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0468 | 0.0552 |
Brugia malayi | hypothetical protein | 0.0147 | 0.0812 | 0.0957 |
Loa Loa (eye worm) | glutathione reductase | 0.0041 | 0.0181 | 0.0213 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0041 | 0.0184 | 0.0191 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.181 | 0.1792 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.0111 | 0.0131 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0023 | 0.0012 |
Brugia malayi | Bromodomain containing protein | 0.0155 | 0.0862 | 0.1016 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0114 | 0.062 | 0.0599 |
Echinococcus granulosus | insulin receptor | 0.0543 | 0.3169 | 0.3712 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0184 | 0.0646 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0041 | 0.0184 | 0.0191 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.004 | 0.0175 | 0.0206 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0068 | 0.0345 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.062 | 0.0731 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0114 | 0.062 | 0.0609 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0107 | 0.0126 |
Trichomonas vaginalis | rotamase, putative | 0.0067 | 0.0336 | 0.0314 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0023 | 0.0027 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0023 | 0.0005 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0143 | 0.0131 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.0021 | 0.0062 | 0.0239 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0048 | 0.0223 | 0.0237 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0093 | 0.0491 | 0.048 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0074 | 0.0376 | 0.0418 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0093 | 0.0491 | 0.048 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0023 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0023 | 0.0027 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0014 | 0.0023 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0107 | 0.0126 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0063 | 0.0314 | 0.2253 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0114 | 0.062 | 0.0731 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0169 | 0.0173 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0067 | 0.0336 | 0.1886 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0025 | 0.0088 | 0.0085 |
Loa Loa (eye worm) | STAT protein | 0.0153 | 0.085 | 0.1003 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0599 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0067 | 0.0336 | 0.1886 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0139 | 0.0765 | 0.4467 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0014 | 0.0023 | 0.0005 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0028 | 0.0107 | 0.0126 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0014 | 0.0022 | 0.0011 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0014 | 0.0023 | 0.0012 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0247 | 0.1408 | 0.1635 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0114 | 0.062 | 0.0609 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0093 | 0.0491 | 0.048 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.169 | 1 | 1 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0014 | 0.0023 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0023 | 0.0027 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0023 | 0.0001 |
Schistosoma mansoni | hypothetical protein | 0.0347 | 0.2004 | 0.2357 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0063 | 0.0314 | 0.2253 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0543 | 0.3169 | 0.3712 |
Mycobacterium leprae | cell division protein FtsZ | 0.0295 | 0.1692 | 0.1673 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.0111 | 0.0105 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0293 | 0.1685 | 0.6643 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0025 | 0.0088 | 0.0066 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0114 | 0.062 | 0.0599 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0025 | 0.0088 | 0.0396 |
Brugia malayi | Protein kinase domain containing protein | 0.03 | 0.1726 | 0.2033 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0543 | 0.3169 | 0.3712 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0065 | 0.0323 | 0.0355 |
Leishmania major | peptidyl-prolyl cis-trans isomerase, putative | 0.0021 | 0.0062 | 0.0239 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0063 | 0.0314 | 0.1164 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0114 | 0.062 | 0.3593 |
Onchocerca volvulus | 0.0029 | 0.0111 | 0.0682 | |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0114 | 0.062 | 0.0609 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0114 | 0.062 | 0.0705 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0434 | 0.2525 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0227 | 0.0268 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0227 | 0.0268 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.181 | 0.1792 |
Brugia malayi | PHD-finger family protein | 0.0053 | 0.0251 | 0.0296 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0115 | 0.0135 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.004 | 0.0175 | 0.0181 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0023 | 0.0001 |
Toxoplasma gondii | PPIC-type PPIASE domain-containing protein | 0.0021 | 0.0062 | 0.004 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.181 | 0.1792 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0114 | 0.062 | 0.3593 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0014 | 0.0022 | 0.0019 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0023 | 0.0027 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0049 | 0.0227 | 0.0205 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0014 | 0.0023 | 0.0005 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0107 | 0.0085 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0014 | 0.0023 | 0.0001 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.0287 | 0.0338 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0014 | 0.0023 | 0.0027 |
Schistosoma mansoni | DNA topoisomerase II | 0.0063 | 0.0314 | 0.0369 |
Brugia malayi | jmjC domain containing protein | 0.0093 | 0.0491 | 0.0578 |
Onchocerca volvulus | 0.0114 | 0.062 | 0.4629 | |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0314 | 0.181 | 0.5471 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0115 | 0.0111 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0114 | 0.062 | 0.3593 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0014 | 0.0022 | 0.0019 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0154 | 0.0853 | 0.0832 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Schistosoma mansoni | dihydropteridine reductase | 0.0114 | 0.062 | 0.0729 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0063 | 0.0314 | 0.031 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0609 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0063 | 0.0314 | 0.031 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0023 | 0.0074 | 0.0087 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0143 | 0.0131 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0015 | 0.0026 | 0.0004 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0025 | 0.0088 | 0.0396 |
Trichomonas vaginalis | pps1 dual specificty phosphatase, putative | 0.0563 | 0.329 | 0.3275 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.181 | 0.1792 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase subunit A | 0.0607 | 0.3551 | 0.3537 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0114 | 0.062 | 0.0599 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0247 | 0.1408 | 0.1635 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0014 | 0.0023 | 0.0001 |
Mycobacterium leprae | Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) | 0.0289 | 0.1661 | 0.1641 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0103 | 0.0553 | 0.0542 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0042 | 0.019 | 0.0224 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0314 | 0.037 |
Schistosoma mansoni | tyrosine kinase | 0.0247 | 0.1408 | 0.1656 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0227 | 0.0205 |
Onchocerca volvulus | 0.003 | 0.0115 | 0.0709 | |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0022 | 0.0026 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0063 | 0.0314 | 0.1751 |
Schistosoma mansoni | rotamase | 0.0068 | 0.0345 | 0.0406 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0041 | 0.0181 | 0.0177 |
Mycobacterium ulcerans | cell division protein FtsZ | 0.0295 | 0.1692 | 0.1673 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0034 | 0.0142 | 0.0142 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0035 | 0.0146 | 0.0147 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0014 | 0.0023 | 0.0012 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0114 | 0.062 | 0.0609 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.169 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0088 | 0.0199 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0014 | 0.0023 | 0.0001 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.169 | 1 | 1 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0014 | 0.0022 | 0.0026 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0065 | 0.0323 | 0.0379 |
Brugia malayi | Bromodomain containing protein | 0.0033 | 0.0136 | 0.016 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0049 | 0.0227 | 0.0205 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0014 | 0.0023 | 0.0001 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0025 | 0.0088 | 0.0066 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0154 | 0.0853 | 0.0832 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0143 | 0.0131 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.0227 | 0.0625 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0115 | 0.0135 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.0114 | 0.062 | 0.0616 |
Onchocerca volvulus | 0.0089 | 0.0471 | 0.3474 | |
Mycobacterium tuberculosis | Probable reductase | 0.0093 | 0.0491 | 0.048 |
Plasmodium falciparum | glutathione reductase | 0.0014 | 0.0022 | 0.0019 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0125 | 0.0147 |
Echinococcus multilocularis | 0.0071 | 0.036 | 0.0399 | |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0025 | 0.0088 | 0.0066 |
Trypanosoma cruzi | ISWI complex protein | 0.0031 | 0.0125 | 0.041 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0014 | 0.0022 | 0.0026 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0169 | 0.0173 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0014 | 0.0022 | 0.0001 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0169 | 0.0446 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0114 | 0.062 | 0.0731 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0435 | 0.0513 |
Toxoplasma gondii | thioredoxin reductase | 0.0041 | 0.0181 | 0.0159 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0067 | 0.0336 | 0.0314 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.0405 | 0.0477 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0063 | 0.0314 | 0.1751 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0599 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0227 | 0.0268 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0114 | 0.062 | 0.073 |
Trypanosoma brucei | ISWI complex protein | 0.0031 | 0.0125 | 0.0617 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0107 | 0.0126 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0089 | 0.0471 | 0.0555 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0036 | 0.0154 | 0.0151 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.0227 | 0.0625 |
Mycobacterium tuberculosis | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0607 | 0.3551 | 0.3544 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0227 | 0.0268 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium leprae | POSSIBLE OXIDOREDUCTASE | 0.0114 | 0.062 | 0.0598 |
Mycobacterium tuberculosis | Cell division protein FtsZ | 0.0295 | 0.1692 | 0.1683 |
Brugia malayi | Cell division protein ftsZ | 0.0145 | 0.0804 | 0.0947 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0014 | 0.0023 | 0.0001 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0014 | 0.0023 | 0.0001 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0028 | 0.0107 | 0.0101 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0227 | 0.1233 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0397 | 0.2304 | 0.2691 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0609 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0028 | 0.0107 | 0.0101 |
Leishmania major | trypanothione reductase | 0.0041 | 0.0181 | 0.0952 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0247 | 0.1408 | 0.1659 |
Schistosoma mansoni | zinc finger protein | 0.0031 | 0.0125 | 0.0147 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0247 | 0.1408 | 0.1662 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0041 | 0.0184 | 0.0972 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0039 | 0.0173 | 0.0178 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0014 | 0.0023 | 0.0001 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0114 | 0.062 | 0.2387 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0103 | 0.0553 | 0.0542 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0031 | 0.0037 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0093 | 0.0491 | 0.0469 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.169 | 1 | 1 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0114 | 0.062 | 0.0705 |
Schistosoma mansoni | hypothetical protein | 0.0347 | 0.2004 | 0.2357 |
Echinococcus granulosus | expressed protein | 0.0068 | 0.0345 | 0.0382 |
Schistosoma mansoni | tyrosine kinase | 0.0242 | 0.1382 | 0.1625 |
Treponema pallidum | cell division protein FtsZ | 0.0295 | 0.1692 | 0.4731 |
Mycobacterium ulcerans | hypothetical protein | 0.0049 | 0.0227 | 0.0205 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0025 | 0.0088 | 0.0085 |
Echinococcus granulosus | peregrin | 0.0033 | 0.0136 | 0.0135 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0115 | 0.011 |
Schistosoma mansoni | lamin | 0.0029 | 0.0111 | 0.0131 |
Schistosoma mansoni | bromodomain containing protein | 0.0131 | 0.0719 | 0.0846 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0014 | 0.0022 | 0.0019 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.0114 | 0.062 | 0.0616 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0108 | 0.0127 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0114 | 0.062 | 0.0599 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0025 | 0.0088 | 0.0066 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0169 | 0.0446 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0023 | 0.0004 |
Toxoplasma gondii | hypothetical protein | 0.0047 | 0.022 | 0.0198 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0014 | 0.0023 | 0.0005 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0041 | 0.0181 | 0.0169 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.004 | 0.0175 | 0.0207 |
Echinococcus multilocularis | insulin receptor | 0.0543 | 0.3169 | 0.3712 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0114 | 0.062 | 0.0609 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0015 | 0.0026 | 0.0004 |
Plasmodium falciparum | glutathione reductase | 0.0041 | 0.0181 | 0.0177 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 0.0491 | 0.0553 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0063 | 0.0314 | 0.1164 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0609 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0599 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0041 | 0.0181 | 0.0633 |
Toxoplasma gondii | propionate-CoA ligase | 0.0014 | 0.0023 | 0.0001 |
Mycobacterium leprae | conserved hypothetical protein | 0.0025 | 0.0088 | 0.0065 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0137 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0154 | 0.0182 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0169 | 0.0199 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0543 | 0.3169 | 0.374 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0014 | 0.0023 | 0.0027 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0025 | 0.0088 | 0.0066 |
Onchocerca volvulus | 0.0114 | 0.062 | 0.4629 | |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0137 | 0.0161 |
Plasmodium falciparum | thioredoxin reductase | 0.0014 | 0.0022 | 0.0019 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.1146 | 0.1352 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0023 | 0.0027 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0067 | 0.0336 | 0.1253 |
Echinococcus multilocularis | geminin | 0.0347 | 0.2004 | 0.2337 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0227 | 0.0205 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0599 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0063 | 0.0314 | 0.1751 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0124 | 0.0676 | 0.0771 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0049 | 0.0227 | 0.0216 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Onchocerca volvulus | 0.0028 | 0.0104 | 0.063 | |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0035 | 0.0146 | 0.0172 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.0114 | 0.062 | 0.0599 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0023 | 0.0012 |
Giardia lamblia | DNA topoisomerase II | 0.0063 | 0.0314 | 0.1628 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0169 | 0.0199 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.169 | 1 | 1 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0023 | 0.0001 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0114 | 0.062 | 0.0599 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.181 | 0.1792 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0049 | 0.0227 | 0.0216 |
Trichomonas vaginalis | rotamase, putative | 0.0068 | 0.0345 | 0.0324 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0048 | 0.0223 | 0.0237 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0025 | 0.0088 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0227 | 0.0268 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0014 | 0.0023 | 0.0027 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0434 | 0.2525 | 1 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0014 | 0.0023 | 0.0012 |
Leishmania major | pteridine reductase 1 | 0.0114 | 0.062 | 0.3593 |
Plasmodium falciparum | thioredoxin reductase | 0.0041 | 0.0181 | 0.0177 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0089 | 0.0471 | 0.0554 |
Onchocerca volvulus | 0.0147 | 0.0812 | 0.6123 | |
Echinococcus multilocularis | zinc finger protein | 0.0042 | 0.0186 | 0.0194 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0115 | 0.0135 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0139 | 0.0765 | 0.2967 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.019 | 0.0223 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0154 | 0.0853 | 0.0842 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0114 | 0.062 | 0.1826 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.1146 | 0.135 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0227 | 0.0268 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0014 | 0.0023 | 0.0012 |
Schistosoma mansoni | tyrosine kinase | 0.0242 | 0.1382 | 0.1625 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0017 | 0.0041 | 0.0048 |
Echinococcus multilocularis | peregrin | 0.0033 | 0.0136 | 0.0135 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0227 | 0.0268 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0063 | 0.0314 | 0.0292 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0227 | 0.0205 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0154 | 0.0182 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0788 | 0.4628 | 0.5432 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0049 | 0.0227 | 0.0625 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0014 | 0.0023 | 0.0001 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0014 | 0.0023 | 0.0012 |
Loa Loa (eye worm) | oxidoreductase | 0.0114 | 0.062 | 0.0731 |
Loa Loa (eye worm) | hypothetical protein | 0.1434 | 0.8474 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1438 | 0.8502 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0231 | 0.1312 | 0.1292 |
Entamoeba histolytica | dual specificity protein phosphatase, putative | 0.0563 | 0.329 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.169 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0019 | 0.0022 |
Giardia lamblia | PHD finger protein 15 | 0.0028 | 0.0107 | 0.0473 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0014 | 0.0022 | 0.0001 |
Onchocerca volvulus | 0.0231 | 0.1312 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0314 | 0.037 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0114 | 0.062 | 0.0599 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0293 | 0.1685 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0023 | 0.0027 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.1436 | 0.8486 | 0.9982 |
Brugia malayi | Neuronal symmetry protein 1 | 0.1436 | 0.8486 | 1 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0014 | 0.0023 | 0.0002 |
Echinococcus granulosus | zinc finger protein | 0.0042 | 0.0186 | 0.0194 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.0111 | 0.0131 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0023 | 0.0004 |
Schistosoma mansoni | protein kinase | 0.1436 | 0.8486 | 0.9982 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0227 | 0.1233 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0169 | 0.0446 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0021 | 0.0062 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0323 | 0.0381 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0014 | 0.0023 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0154 | 0.0182 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0014 | 0.0023 | 0.0004 |
Echinococcus granulosus | lamin | 0.0029 | 0.0111 | 0.0105 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.169 | 1 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0036 | 0.0154 | 0.0151 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0314 | 0.181 | 1 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0114 | 0.062 | 0.0599 |
Echinococcus granulosus | dnaJ subfamily B | 0.0397 | 0.2304 | 0.2691 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0014 | 0.0023 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0026 | 0.0031 |
Trypanosoma cruzi | ISWI complex protein | 0.0031 | 0.0125 | 0.041 |
Trypanosoma brucei | trypanothione reductase | 0.0041 | 0.0181 | 0.0952 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0035 | 0.0146 | 0.0172 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0041 | 0.0181 | 0.0213 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0048 | 0.0223 | 0.0262 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0068 | 0.0345 | 0.0408 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0023 | 0.0012 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0023 | 0.0012 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0247 | 0.1408 | 0.1635 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0114 | 0.062 | 0.073 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0023 | 0.0001 |
Schistosoma mansoni | hypothetical protein | 0.0397 | 0.2304 | 0.271 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0114 | 0.062 | 0.2387 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0068 | 0.0345 | 0.0407 |
Echinococcus multilocularis | expressed protein | 0.0068 | 0.0345 | 0.0382 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0063 | 0.0314 | 0.1751 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.1436 | 0.8486 | 0.9982 |
Plasmodium vivax | glutathione reductase, putative | 0.0041 | 0.0181 | 0.0177 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0089 | 0.0471 | 0.053 |
Onchocerca volvulus | 0.0049 | 0.0227 | 0.1584 | |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsZ | 0.0295 | 0.1692 | 0.1673 |
Brugia malayi | glutathione reductase | 0.0041 | 0.0181 | 0.0213 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0063 | 0.0314 | 0.0344 |
Echinococcus granulosus | jumonji domain containing protein | 0.0039 | 0.0173 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0432 | 0.2512 | 0.2965 |
Loa Loa (eye worm) | oxidoreductase | 0.0014 | 0.0023 | 0.0027 |
Schistosoma mansoni | tyrosine kinase | 0.0543 | 0.3169 | 0.3728 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0114 | 0.062 | 0.0729 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0314 | 0.181 | 0.5067 |
Brugia malayi | Probable DNA topoisomerase II | 0.0063 | 0.0314 | 0.0369 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0014 | 0.0023 | 0.0001 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0293 | 0.1685 | 0.6643 |
Schistosoma mansoni | tyrosine kinase | 0.0242 | 0.1382 | 0.1625 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.08 | 0.0945 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0104 | 0.0123 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0063 | 0.0314 | 0.1164 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0247 | 0.1408 | 0.1635 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.0111 | 0.0131 |
Echinococcus multilocularis | musashi | 0.0029 | 0.0111 | 0.0105 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1438 | 0.8502 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.0031 | 0.0036 |
Brugia malayi | Thioredoxin reductase | 0.0041 | 0.0181 | 0.0213 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.005 | 0.0238 | 0.086 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0107 | 0.0085 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0103 | 0.0553 | 0.0542 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0014 | 0.0023 | 0.0001 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0288 | 0.0266 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0155 | 0.0858 | 0.0848 |
Schistosoma mansoni | tyrosine kinase | 0.0247 | 0.1408 | 0.1656 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.169 | 1 | 1 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0063 | 0.0314 | 0.2253 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0014 | 0.0023 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0154 | 0.0182 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1438 | 0.8502 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0093 | 0.0491 | 0.048 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0471 | 0.0556 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0035 | 0.0146 | 0.0147 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0247 | 0.1408 | 0.1635 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0063 | 0.0314 | 0.0369 |
Mycobacterium leprae | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI | 0.0114 | 0.062 | 0.0598 |
Plasmodium vivax | DNA gyrase subunit A, putative | 0.0607 | 0.3551 | 0.3549 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0036 | 0.0154 | 0.0132 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0114 | 0.062 | 0.2387 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0114 | 0.062 | 0.3593 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0104 | 0.0123 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0025 | 0.0088 | 0.0066 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0105 | 0.0098 |
Plasmodium falciparum | phd finger protein, putative | 0.0028 | 0.0107 | 0.0103 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0014 | 0.0023 | 0.0012 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0014 | 0.0023 | 0.0027 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.0107 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0406 | 0.0479 |
Schistosoma mansoni | tyrosine kinase | 0.0247 | 0.1408 | 0.1656 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0297 | 0.0349 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0124 | 0.0676 | 0.0771 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0023 | 0.0001 |
Leishmania major | oxidoreductase-like protein | 0.0114 | 0.062 | 0.3593 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0065 | 0.0323 | 0.0355 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0293 | 0.1685 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0104 | 0.0123 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.0111 | 0.0131 |
Brugia malayi | Protein kinase domain containing protein | 0.0543 | 0.3169 | 0.3734 |
Chlamydia trachomatis | DNA gyrase subunit A | 0.0607 | 0.3551 | 0.3537 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0114 | 0.062 | 0.0599 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0114 | 0.062 | 0.0609 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0019 | 0.0022 |
Leishmania major | DNA topoisomerase ii | 0.0063 | 0.0314 | 0.1751 |
Loa Loa (eye worm) | STE/STE11/ASK protein kinase | 0.0434 | 0.2525 | 0.298 |
Mycobacterium ulcerans | DNA gyrase subunit A | 0.0607 | 0.3551 | 0.3537 |
Echinococcus multilocularis | lamin | 0.0029 | 0.0111 | 0.0105 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.0227 | 0.0205 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0169 | 0.0199 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0036 | 0.0154 | 0.0143 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0063 | 0.0314 | 0.0344 |
Leishmania major | hypothetical protein, conserved | 0.0031 | 0.0125 | 0.0617 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0143 | 0.0131 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0021 | 0.0062 | 0.0159 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0028 | 0.0107 | 0.0126 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | > 50 uM | Antifungal activity against Cryptococcus neoformans by broth microdilution method | ChEMBL. | 21920743 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.