Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Possible fatty acyl-CoA reductase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Brugia malayi | Retinol dehydrogenase 12 | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Leishmania major | 3-keto-dihydrosphingosine reductase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0017 | 0.0421 | 0.0485 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0196 | 0.8679 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0017 | 0.0421 | 0.0421 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0017 | 0.0421 | 0.0421 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0017 | 0.0421 | 0.0485 |
Leishmania major | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Echinococcus granulosus | WW domain containing oxidoreductase | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 1 homolog | 0.0196 | 0.8679 | 1 |
Echinococcus granulosus | Dehydrogenase:reductase SDR family | 0.0196 | 0.8679 | 1 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0017 | 0.0421 | 0.0485 |
Entamoeba histolytica | 3-ketodihydrosphingosine reductase protein, putative | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0045 | 0.0045 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0196 | 0.8679 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0017 | 0.0421 | 0.0421 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0196 | 0.8679 | 0.5 |
Mycobacterium tuberculosis | Possible ketoacyl reductase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Trichomonas vaginalis | steroid dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0142 | 0.6155 | 0.7092 |
Echinococcus granulosus | 3 ketodihydrosphingosine reductase | 0.0196 | 0.8679 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0017 | 0.0421 | 0.0421 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0017 | 0.0421 | 0.0485 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0196 | 0.8679 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0138 | 0.5972 | 0.6881 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Onchocerca volvulus | 0.0064 | 0.2579 | 0.2971 | |
Toxoplasma gondii | sterol carrier protein-2 HAD-2SCP-2 | 0.0196 | 0.8679 | 1 |
Brugia malayi | Hypothetical oxidoreductase F56D1.5 | 0.0196 | 0.8679 | 0.8679 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0017 | 0.0421 | 0.0421 |
Mycobacterium ulcerans | short-chain type oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0017 | 0.0421 | 0.0421 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0017 | 0.0421 | 0.0485 |
Schistosoma mansoni | jun-related protein | 0.0066 | 0.2682 | 0.309 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | carbonyl reductase | 0.0196 | 0.8679 | 1 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0196 | 0.8679 | 0.8679 |
Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Leishmania major | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | dehydrogenase | 0.0196 | 0.8679 | 0.8679 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0196 | 0.8679 | 1 |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0196 | 0.8679 | 1 |
Trypanosoma brucei | beta-D-hydroxybutyrate dehydrogenase | 0.0196 | 0.8679 | 1 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.4997 | 0.4997 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0421 | 0.0421 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Brugia malayi | Dehydrogenases, short chain protein 2 | 0.0196 | 0.8679 | 0.8679 |
Entamoeba histolytica | hypothetical protein | 0.0196 | 0.8679 | 1 |
Mycobacterium tuberculosis | Possible short-chain dehydrogenase EphD | 0.0196 | 0.8679 | 0.5 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0017 | 0.0421 | 0.0485 |
Schistosoma mansoni | oxidoreductase short chain dehydrogenase/reductase family | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0017 | 0.0421 | 0.0421 |
Giardia lamblia | Short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0017 | 0.0421 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0196 | 0.8679 | 1 |
Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0017 | 0.0421 | 0.0485 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Trypanosoma brucei | 3-keto-dihydrosphingosine reductase | 0.0196 | 0.8679 | 1 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0196 | 0.8679 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.0017 | 0.0421 | 0.0485 |
Leishmania major | pteridine reductase 1 | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0017 | 0.0421 | 0.0485 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | dehydrogenases, short chain protein 2 | 0.0196 | 0.8679 | 0.8679 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0009 | 0.0045 | 0.0052 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0225 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0017 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0421 | 0.0421 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0017 | 0.0421 | 0.0421 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0082 | 0.3386 | 0.3902 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0017 | 0.0421 | 0.0485 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0017 | 0.0421 | 0.0485 |
Echinococcus multilocularis | jun protein | 0.0082 | 0.3386 | 0.3902 |
Mycobacterium tuberculosis | Probable shortchain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0196 | 0.8679 | 0.5 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0009 | 0.0045 | 0.0045 |
Leishmania major | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Mycobacterium leprae | Probable oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | retinol dehydrogenase 13 | 0.0196 | 0.8679 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0142 | 0.6155 | 0.6155 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Echinococcus granulosus | oxidoreductase | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0045 | 0.0045 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor | 0.0196 | 0.8679 | 0.8679 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0196 | 0.8679 | 1 |
Brugia malayi | hypothetical protein | 0.0064 | 0.2579 | 0.2579 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Leishmania major | short chain dehydrogenase-like protein | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0196 | 0.8679 | 1 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0196 | 0.8679 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0196 | 0.8679 | 0.5 |
Onchocerca volvulus | 0.0017 | 0.0421 | 0.0485 | |
Schistosoma mansoni | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0017 | 0.0421 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0196 | 0.8679 | 1 |
Leishmania major | short chain dehydrogenase, putative | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | ecdysteroid receptor | 0.0017 | 0.0421 | 0.0421 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | 3-keto-dihydrosphingosine reductase | 0.0196 | 0.8679 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Toxoplasma gondii | 3-ketoacyl-CoA reductase, putative | 0.0196 | 0.8679 | 1 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0045 | 0.0045 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Toxoplasma gondii | carbonyl reductase 1, putative | 0.0196 | 0.8679 | 1 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0196 | 0.8679 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0009 | 0.0045 | 0.0045 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0017 | 0.0421 | 0.0421 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0142 | 0.6182 | 0.7123 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0196 | 0.8679 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0017 | 0.0421 | 0.0485 |
Echinococcus granulosus | hypothetical protein | 0.0196 | 0.8679 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0017 | 0.0421 | 0.0485 |
Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Echinococcus multilocularis | oxidoreductase | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0017 | 0.0421 | 0.0421 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium leprae | ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | short-chain dehydrogenase/reductase | 0.0196 | 0.8679 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0009 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0421 | 0.0421 |
Mycobacterium ulcerans | oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | carbonyl reductase | 0.0196 | 0.8679 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0017 | 0.0421 | 0.0421 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0196 | 0.8679 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | bZIP transcription factor family protein | 0.0082 | 0.3386 | 0.3386 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0196 | 0.8679 | 1 |
Plasmodium vivax | steroid dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0196 | 0.8679 | 0.5 |
Leishmania major | short chain dehydrogenase/reductase, putative | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0017 | 0.0421 | 0.0485 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Leishmania major | short chain dehydrogenase/reductase, putative | 0.0196 | 0.8679 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0017 | 0.0421 | 0.0485 |
Brugia malayi | oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0045 | 0.0045 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0017 | 0.0421 | 0.0421 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0042 | 0.1545 | 0.178 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenases/reductase, putative | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0196 | 0.8679 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0017 | 0.0421 | 0.0421 |
Schistosoma mansoni | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Giardia lamblia | Reductase, putative | 0.0196 | 0.8679 | 1 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase 3, putative | 0.0196 | 0.8679 | 1 |
Leishmania major | oxidoreductase-like protein | 0.0196 | 0.8679 | 0.5 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0196 | 0.8679 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0017 | 0.0421 | 0.0485 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0009 | 0.0045 | 0.0052 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Schistosoma mansoni | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0017 | 0.0421 | 0.0485 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0196 | 0.8679 | 1 |
Brugia malayi | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium tuberculosis | Probable short-chain dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.2682 | 0.309 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0017 | 0.0421 | 0.0485 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0017 | 0.0421 | 0.0421 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Trypanosoma brucei | 3-ketoacyl-CoA reductase, putative | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0017 | 0.0421 | 0.0485 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 1 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Brugia malayi | Dehydrogenases, short chain protein 30 | 0.0196 | 0.8679 | 0.8679 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase 2 | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0017 | 0.0421 | 0.0485 |
Onchocerca volvulus | Sepiapterin reductase homolog | 0.0196 | 0.8679 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0017 | 0.0421 | 0.0421 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0017 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0017 | 0.0421 | 0.0485 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.4997 | 0.4997 |
Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0017 | 0.0421 | 0.0421 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0017 | 0.0421 | 0.0421 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Mycobacterium leprae | PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE | 0.0196 | 0.8679 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 1 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Toxoplasma gondii | oxidoreductase, putative | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Mycobacterium tuberculosis | Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0082 | 0.3386 | 0.3902 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0196 | 0.8679 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium tuberculosis | Probable short chain alcohol dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | retinal dehydrogenase | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0017 | 0.0421 | 0.0421 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0196 | 0.8679 | 1 |
Mycobacterium tuberculosis | Possible iron-regulated short-chain dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0017 | 0.0421 | 0.0485 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0196 | 0.8679 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0017 | 0.0421 | 0.0485 |
Brugia malayi | steroid hormone receptor | 0.0017 | 0.0421 | 0.0421 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0017 | 0.0421 | 0.0421 |
Schistosoma mansoni | carbonyl reductase | 0.0196 | 0.8679 | 1 |
Trichomonas vaginalis | hydroxyacyl dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | carveol-like dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0017 | 0.0421 | 0.0421 |
Schistosoma mansoni | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0017 | 0.0421 | 0.0421 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | acetyltransferase | 0.0142 | 0.6155 | 0.6155 |
Giardia lamblia | Hypothetical protein | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0045 | 0.0045 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0017 | 0.0421 | 0.0485 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0017 | 0.0421 | 0.0421 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | Dehydrogenase:reductase SDR family | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Leishmania major | short chain dehydrogenase, putative | 0.0196 | 0.8679 | 0.5 |
Entamoeba histolytica | oxidoreductase, short chain dehydrogenase/reductase family | 0.0196 | 0.8679 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0017 | 0.0421 | 0.0485 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0009 | 0.0045 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.3283 | 0.3283 |
Toxoplasma gondii | oxidoreductase, putative | 0.0196 | 0.8679 | 1 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0421 | 0.0421 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0017 | 0.0421 | 0.0485 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Trichomonas vaginalis | estradiol 17 beta-dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium ulcerans | dehydrogenase/decarboxylase protein | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0017 | 0.0421 | 0.0485 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0017 | 0.0421 | 0.0485 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0196 | 0.8679 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short-chain membrane-associated dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0017 | 0.0421 | 0.0421 |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0017 | 0.0421 | 0.0485 |
Mycobacterium tuberculosis | Probable short-chain type oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0421 | 0.0421 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0196 | 0.8679 | 1 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0009 | 0.0045 | 0.0052 |
Echinococcus granulosus | steroid dehydrogenase | 0.0196 | 0.8679 | 1 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0017 | 0.0421 | 0.0485 |
Echinococcus multilocularis | 3 ketodihydrosphingosine reductase | 0.0196 | 0.8679 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0017 | 0.0421 | 0.0485 |
Echinococcus granulosus | hypothetical protein | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Leishmania major | hypothetical protein, conserved | 0.0196 | 0.8679 | 0.5 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0196 | 0.8679 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0017 | 0.0421 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0421 | 0.0421 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0196 | 0.8679 | 1 |
Trypanosoma cruzi | quinonoid dihydropteridine reductase, putative | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | dehydrogenases, short chain protein 9 | 0.0196 | 0.8679 | 0.8679 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0045 | 0.0045 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0142 | 0.6155 | 0.7092 |
Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0196 | 0.8679 | 0.5 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Brugia malayi | nuclear hormone receptor | 0.0017 | 0.0421 | 0.0421 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0196 | 0.8679 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Echinococcus multilocularis | epidermal retinal dehydrogenase 2 | 0.0196 | 0.8679 | 1 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Echinococcus granulosus | jun protein | 0.0082 | 0.3386 | 0.3902 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Giardia lamblia | Oxidoreductase, short chain dehydrogenase/reductase family | 0.0196 | 0.8679 | 1 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0196 | 0.8679 | 1 |
Mycobacterium leprae | Possible short-chain dehydrogenase EphD | 0.0196 | 0.8679 | 0.5 |
Plasmodium falciparum | oxidoreductase, short-chain dehydrogenase family, putative | 0.0196 | 0.8679 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0009 | 0.0045 | 0.0045 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Leishmania major | dehydrogenase-like protein | 0.0196 | 0.8679 | 0.5 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0196 | 0.8679 | 1 |
Echinococcus granulosus | epidermal retinal dehydrogenase 2 | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 0.8679 | 0.8679 |
Plasmodium falciparum | steroid dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Loa Loa (eye worm) | dehydrogenase | 0.0196 | 0.8679 | 0.8679 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0196 | 0.8679 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0196 | 0.8679 | 0.5 |
Echinococcus multilocularis | estradiol 17 beta dehydrogenase 12 | 0.0196 | 0.8679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.8679 | 0.8679 |
Schistosoma mansoni | short chain dehydrogenase | 0.0196 | 0.8679 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0196 | 0.8679 | 0.8679 |
Onchocerca volvulus | 0.0196 | 0.8679 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0421 | 0.0421 |
Mycobacterium tuberculosis | Decaprenylphosphoryl-D-2-keto erythro pentose reductase | 0.0196 | 0.8679 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.4997 | 0.4997 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 at 10 uM preincubated for 15 mins measured after 5 mins by enzyme immunoassay | ChEMBL. | 21958737 | |
Inhibition (binding) | = 7 % | Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production at 10 uM preincubated for 15 mins measured after 15 mins by enzyme immunoassay | ChEMBL. | 21958737 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.