Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | quinonoid dihydropteridine reductase, putative | 0.0009 | 0.5 | 0.5 |
Brugia malayi | dehydrogenases, short chain protein 9 | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Echinococcus multilocularis | epidermal retinal dehydrogenase 2 | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | 3-keto-dihydrosphingosine reductase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible iron-regulated short-chain dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0009 | 0.5 | 0.5 |
Plasmodium vivax | steroid dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase 3, putative | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Trypanosoma brucei | beta-D-hydroxybutyrate dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | Dehydrogenase:reductase SDR family | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0009 | 0.5 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0009 | 0.5 | 0.5 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0009 | 0.5 | 0.5 |
Mycobacterium leprae | Possible short-chain dehydrogenase EphD | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | 3 ketodihydrosphingosine reductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | short chain dehydrogenase-like protein | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0009 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | carbonyl reductase | 0.0009 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | 3-keto-dihydrosphingosine reductase | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | Sepiapterin reductase homolog | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Entamoeba histolytica | oxidoreductase, short chain dehydrogenase/reductase family | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Decaprenylphosphoryl-D-2-keto erythro pentose reductase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible ketoacyl reductase | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, putative | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0009 | 0.5 | 0.5 |
Toxoplasma gondii | 3-ketoacyl-CoA reductase, putative | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Entamoeba histolytica | 3-ketodihydrosphingosine reductase protein, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type oxidoreductase | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Giardia lamblia | Reductase, putative | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible fatty acyl-CoA reductase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0009 | 0.5 | 0.5 |
Brugia malayi | Dehydrogenases, short chain protein 2 | 0.0009 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short chain alcohol dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | estradiol 17 beta-dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short-chain dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | WW domain containing oxidoreductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | short chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable shortchain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | dehydrogenase | 0.0009 | 0.5 | 0.5 |
Giardia lamblia | Short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Plasmodium falciparum | oxidoreductase, short-chain dehydrogenase family, putative | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible short-chain dehydrogenase EphD | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | hydroxyacyl dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Leishmania major | short chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | oxidoreductase short chain dehydrogenase/reductase family | 0.0009 | 0.5 | 0.5 |
Leishmania major | short chain dehydrogenase/reductase, putative | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | estradiol 17 beta dehydrogenase 12 | 0.0009 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, putative | 0.0009 | 0.5 | 0.5 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Mycobacterium ulcerans | ketoacyl reductase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | Dehydrogenase:reductase SDR family | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | pteridine reductase 1 | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0009 | 0.5 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium leprae | Probable oxidoreductase | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain membrane-associated dehydrogenase | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Brugia malayi | dehydrogenases, short chain protein 2 | 0.0009 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Toxoplasma gondii | carbonyl reductase 1, putative | 0.0009 | 0.5 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | retinol dehydrogenase 13 | 0.0009 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 1 homolog | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | epidermal retinal dehydrogenase 2 | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium leprae | ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | 0.0009 | 0.5 | 0.5 |
Brugia malayi | Hypothetical oxidoreductase F56D1.5 | 0.0009 | 0.5 | 0.5 |
Giardia lamblia | Oxidoreductase, short chain dehydrogenase/reductase family | 0.0009 | 0.5 | 0.5 |
Leishmania major | oxidoreductase-like protein | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | short chain dehydrogenase/reductase, putative | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | retinal dehydrogenase | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium leprae | PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | carbonyl reductase | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | steroid dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0009 | 0.5 | 0.5 |
Brugia malayi | Retinol dehydrogenase 12 | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenases/reductase, putative | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type oxidoreductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0009 | 0.5 | 0.5 |
Plasmodium falciparum | steroid dehydrogenase, putative | 0.0009 | 0.5 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0009 | 0.5 | 0.5 |
Brugia malayi | D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Leishmania major | dehydrogenase-like protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Echinococcus multilocularis | 3 ketodihydrosphingosine reductase | 0.0009 | 0.5 | 0.5 |
Brugia malayi | Dehydrogenases, short chain protein 30 | 0.0009 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Trypanosoma brucei | 3-ketoacyl-CoA reductase, putative | 0.0009 | 0.5 | 0.5 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | dehydrogenase/decarboxylase protein | 0.0009 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | carveol-like dehydrogenase | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase 2 | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | carbonyl reductase | 0.0009 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0009 | 0.5 | 0.5 | |
Trypanosoma brucei | 3-keto-dihydrosphingosine reductase | 0.0009 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0009 | 0.5 | 0.5 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0009 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0009 | 0.5 | 0.5 |
Toxoplasma gondii | sterol carrier protein-2 HAD-2SCP-2 | 0.0009 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 72 uM | Inhibition of aromatase after 10 mins preincubation by plate reader relative to control | ChEMBL. | 21978950 |
Inhibition (binding) | = -3.4 % | Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells at 50 uM pretreated 15 mins before LPS challenge measured after 20 hrs relative to control | ChEMBL. | 21978950 |
Inhibition (binding) | = 40 % | Inhibition of aromatase at 50 uM after 10 mins preincubation by plate reader relative to control | ChEMBL. | 21978950 |
Survival (binding) | = 94.2 % | Induction of quinone reductase 1 activity in mouse Hepa-1c1c7 cells assessed as cell survival at 50 uM by MTT assay relative to control | ChEMBL. | 21978950 |
Survival (functional) | = 104.6 % | Antiproliferative activity against human MCF7 cells assessed as survival at 50 uM after 72 hrs by SRB assay relative to control | ChEMBL. | 21978950 |
Survival (binding) | = 137.3 % | Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells assessed as cell survival at 50 uM pretreated 15 mins before LPS challenge measured after 20 hrs relative to control | ChEMBL. | 21978950 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.