Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Peroxidase homolog | 0.007 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0072 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0072 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.007 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0072 | 1 | 1 |
Onchocerca volvulus | 0.007 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0072 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.007 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0072 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.007 | 0 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0072 | 1 | 1 |
Onchocerca volvulus | 0.007 | 0 | 0.5 | |
Onchocerca volvulus | Peroxidase homolog | 0.007 | 0 | 0.5 |
Onchocerca volvulus | Dual oxidase homolog | 0.007 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0072 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0072 | 1 | 1 |
Onchocerca volvulus | 0.007 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0072 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0072 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.