Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0043 | 0.0062 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0117 | 0.0432 | 0.1143 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0043 | 0.0062 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0039 | 0.0053 | 0.0102 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0153 | 0.0608 | 0.1513 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0174 | 0.0709 | 0.1783 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0039 | 0.0053 | 0.0102 |
Echinococcus multilocularis | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.0072 | 0.0213 | 0.0192 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0041 | 0.0062 | 0.0093 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0174 | 0.0709 | 0.1877 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Entamoeba histolytica | thymidine kinase, putative | 0.0803 | 0.3778 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0041 | 0.0062 | 0.005 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0153 | 0.0608 | 0.0588 |
Schistosoma mansoni | lamin | 0.0055 | 0.013 | 0.0109 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0096 | 0.0074 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0153 | 0.0608 | 0.0592 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0022 | 0.003 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0153 | 0.0608 | 0.1513 |
Brugia malayi | Cytochrome P450 family protein | 0.0115 | 0.0422 | 0.0793 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0062 | 0.0163 |
Echinococcus granulosus | geminin | 0.0339 | 0.1518 | 0.1504 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0673 | 0.0653 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0153 | 0.0608 | 0.8299 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0039 | 0.0053 | 0.0148 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0213 | 0.0456 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0039 | 0.0053 | 0.0148 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0059 | 0.0149 | 0.0127 |
Leishmania major | cytochrome p450-like protein | 0.0039 | 0.0053 | 0.0026 |
Schistosoma mansoni | NADH-ubiquinone oxidoreductase | 0.0072 | 0.0213 | 0.0192 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0052 | 0.0114 | 0.0302 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0213 | 0.0456 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0059 | 0.0149 | 0.0132 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0043 | 0.007 |
Leishmania major | thymidylate kinase-like protein | 0.0149 | 0.0591 | 0.1466 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.0116 | 0.1344 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0052 | 0.0114 | 0.0302 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0149 | 0.0591 | 0.1466 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0043 | 0.0062 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0156 | 0.0623 | 0.0603 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0153 | 0.0608 | 0.0592 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0059 | 0.0149 | 0.1831 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0044 | 0.008 | 0.0098 |
Plasmodium vivax | thymidylate kinase, putative | 0.0149 | 0.0591 | 0.8273 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0023 | 0.0033 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.0116 | 0.0194 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0083 | 0.0266 | 0.0596 |
Echinococcus multilocularis | lamin dm0 | 0.0055 | 0.013 | 0.0109 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0149 | 0.0591 | 0.1467 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0039 | 0.0053 | 0.0148 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Brugia malayi | Inositol-1 | 0.0117 | 0.0432 | 0.0813 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Echinococcus multilocularis | thymidylate kinase | 0.0149 | 0.0591 | 0.057 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0213 | 0.0456 |
Echinococcus granulosus | intermediate filament protein | 0.0055 | 0.013 | 0.0113 |
Echinococcus multilocularis | thymidine kinase | 0.2077 | 0.9992 | 1 |
Schistosoma mansoni | thymidine kinase | 0.2077 | 0.9992 | 1 |
Trypanosoma brucei | RNA helicase, putative | 0.0311 | 0.1379 | 0.365 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0117 | 0.0432 | 0.104 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0043 | 0.0062 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0072 | 0.0213 | 0.0456 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0174 | 0.0709 | 0.0689 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0104 | 0.0187 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0039 | 0.0053 | 0.0148 |
Brugia malayi | Cytochrome P450 family protein | 0.0066 | 0.0185 | 0.0341 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.0163 |
Onchocerca volvulus | 0.0049 | 0.0104 | 0.0726 | |
Loa Loa (eye worm) | thymidylate synthase | 0.0174 | 0.0709 | 0.1176 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0059 | 0.0149 | 0.1353 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0153 | 0.0608 | 0.8299 |
Loa Loa (eye worm) | calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase | 0.0153 | 0.0608 | 0.1007 |
Echinococcus granulosus | thymidylate synthase | 0.0174 | 0.0709 | 0.0693 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0039 | 0.0053 | 0.0148 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0096 | 0.0074 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0117 | 0.0432 | 0.104 |
Echinococcus multilocularis | musashi | 0.0055 | 0.013 | 0.0109 |
Loa Loa (eye worm) | cytochrome P450 | 0.0039 | 0.0053 | 0.0078 |
Leishmania major | cathepsin L-like protease | 0.007 | 0.0206 | 0.0436 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0213 | 0.0456 |
Leishmania major | thymidine kinase, putative | 0.0803 | 0.3778 | 1 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0059 | 0.0149 | 0.0284 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0023 | 0.0001 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0059 | 0.0149 | 0.0273 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0041 | 0.0062 | 0.005 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.0163 |
Giardia lamblia | Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative | 0.0072 | 0.0213 | 0.0152 |
Toxoplasma gondii | exonuclease III APE | 0.0059 | 0.0149 | 0.0209 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0059 | 0.0149 | 0.159 |
Echinococcus granulosus | lamin dm0 | 0.0055 | 0.013 | 0.0113 |
Schistosoma mansoni | phosphoglucomutase | 0.0044 | 0.008 | 0.0058 |
Brugia malayi | RNase H family protein | 0.0044 | 0.008 | 0.0141 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0153 | 0.0608 | 0.1513 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0117 | 0.0432 | 0.1041 |
Leishmania major | cytochrome p450-like protein | 0.0039 | 0.0053 | 0.0026 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0039 | 0.0053 | 0.0102 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0043 | 0.0021 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0039 | 0.0053 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0043 | 0.0062 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0117 | 0.0432 | 0.104 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.005 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0039 | 0.0053 | 0.0026 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0043 | 0.0021 |
Echinococcus multilocularis | dna polymerase kappa | 0.0041 | 0.0062 | 0.004 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0023 | 0.0001 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma brucei | ribonuclease H1 | 0.0044 | 0.008 | 0.0211 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0117 | 0.0432 | 0.104 |
Mycobacterium ulcerans | thymidylate synthase | 0.0174 | 0.0709 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0039 | 0.0053 | 0.0102 |
Trichomonas vaginalis | set domain proteins, putative | 0.0261 | 0.1136 | 0.2927 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0041 | 0.0062 | 0.004 |
Echinococcus granulosus | thymidylate kinase | 0.0149 | 0.0591 | 0.0575 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.007 | 0.0206 | 0.0436 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.007 | 0.0206 | 0.0436 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.0366 | 0.0688 |
Schistosoma mansoni | thymidylate kinase | 0.0149 | 0.0591 | 0.057 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Leishmania major | cytochrome p450-like protein | 0.0066 | 0.0185 | 0.0379 |
Chlamydia trachomatis | thymidylate kinase | 0.0149 | 0.0591 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.007 | 0.0206 | 0.0436 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0039 | 0.0053 | 0.014 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0023 | 0.0001 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.0163 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0149 | 0.0591 | 0.1466 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0041 | 0.0062 | 0.0191 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0022 | 0.0005 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0039 | 0.0053 | 0.0148 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0104 | 0.0372 | 0.4939 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0149 | 0.0591 | 0.5098 |
Giardia lamblia | CDC8 | 0.0149 | 0.0591 | 0.0532 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.1255 | 0.5985 | 0.5983 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0053 | 0.0031 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0236 | 0.1013 | 1 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0039 | 0.0053 | 0.0148 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.0116 | 0.0306 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0066 | 0.0185 | 0.0379 |
Loa Loa (eye worm) | inositol-1 | 0.0117 | 0.0432 | 0.0712 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0174 | 0.0709 | 1 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0039 | 0.0053 | 0.0148 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0803 | 0.3778 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0043 | 0.0021 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0117 | 0.0432 | 0.6886 |
Trypanosoma cruzi | cyclic nucleotide phosphodiesterase | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0066 | 0.0185 | 0.0379 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0039 | 0.0053 | 0.0148 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.1255 | 0.5985 | 0.5981 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.1255 | 0.5985 | 0.5983 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0039 | 0.0053 | 0.0148 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Schistosoma mansoni | calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.1255 | 0.5985 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0041 | 0.0062 | 0.005 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.8299 |
Onchocerca volvulus | 0.0174 | 0.0709 | 0.6162 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0023 | 0.0001 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0039 | 0.0053 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.1046 | 0.1738 |
Echinococcus granulosus | thymidine kinase | 0.2077 | 0.9992 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0096 | 0.0079 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0039 | 0.0053 | 0.0102 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0096 | 0.0074 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0153 | 0.0608 | 0.161 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0137 | 0.0529 | 0.0513 |
Schistosoma mansoni | phosphoglucomutase | 0.0044 | 0.008 | 0.0058 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0039 | 0.0053 | 0.0148 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0149 | 0.0591 | 0.1466 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.0062 | 0.004 |
Schistosoma mansoni | DNA polymerase eta | 0.0041 | 0.0062 | 0.004 |
Loa Loa (eye worm) | intermediate filament protein | 0.0055 | 0.013 | 0.0208 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0117 | 0.0432 | 0.104 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0116 | 0.0209 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0096 | 0.015 |
Giardia lamblia | Hypothetical protein | 0.0072 | 0.0213 | 0.0152 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.005 |
Giardia lamblia | Hypothetical protein | 0.0072 | 0.0213 | 0.0152 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0044 | 0.008 | 0.0098 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0096 | 0.0074 |
Brugia malayi | hypothetical protein | 0.0083 | 0.0266 | 0.0495 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0041 | 0.0062 | 0.005 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Echinococcus multilocularis | dna polymerase eta | 0.0041 | 0.0062 | 0.004 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0022 | 0.0005 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0041 | 0.0062 | 0.0163 |
Schistosoma mansoni | camp-specific cyclic nucleotide phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0043 | 0.007 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0043 | 0.007 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0059 | 0.0149 | 0.0563 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0041 | 0.0062 | 0.005 |
Echinococcus multilocularis | geminin | 0.0339 | 0.1518 | 0.15 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Trypanosoma brucei | cAMP phosphodiesterase A, putative | 0.0153 | 0.0608 | 0.161 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0039 | 0.0053 | 0.0102 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0039 | 0.0053 | 0.0026 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0066 | 0.0185 | 0.0298 |
Leishmania major | hypothetical protein, conserved | 0.0059 | 0.0149 | 0.0283 |
Echinococcus granulosus | ribonuclease H1 | 0.0044 | 0.008 | 0.0062 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0153 | 0.0608 | 0.0588 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0055 | 0.013 | 0.0237 |
Onchocerca volvulus | 0.0055 | 0.013 | 0.0961 | |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0043 | 0.0021 |
Schistosoma mansoni | ap endonuclease | 0.0059 | 0.0149 | 0.0127 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0039 | 0.0053 | 0.0148 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0083 | 0.0266 | 0.2293 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0059 | 0.0149 | 0.0284 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0044 | 0.008 | 0.0098 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0043 | 0.0021 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.0116 | 0.0154 |
Echinococcus granulosus | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.0072 | 0.0213 | 0.0196 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0039 | 0.0053 | 0.0102 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0039 | 0.0053 | 0.0102 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.0116 | 0.0194 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0039 | 0.0053 | 0.0148 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0153 | 0.0608 | 0.1513 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0126 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0207 | 0.0336 |
Plasmodium vivax | cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.8527 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0039 | 0.0053 | 0.0102 |
Trypanosoma brucei | unspecified product | 0.0041 | 0.0062 | 0.0163 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0039 | 0.0053 | 0.0026 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma cruzi | cAMP-specific phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.1103 | 0.524 | 0.8754 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0057 | 0.0139 | 0.0117 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0072 | 0.0213 | 0.0456 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.005 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0104 | 0.0372 | 0.3391 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0059 | 0.0149 | 0.1353 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0213 | 0.0455 |
Echinococcus multilocularis | ribonuclease H1 | 0.0044 | 0.008 | 0.0058 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0041 | 0.0062 | 0.0106 |
Onchocerca volvulus | 0.0055 | 0.013 | 0.0961 | |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0174 | 0.0709 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0043 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0207 | 0.0185 |
Onchocerca volvulus | 0.0261 | 0.1136 | 1 | |
Echinococcus granulosus | dna polymerase kappa | 0.0041 | 0.0062 | 0.0044 |
Trypanosoma brucei | cAMP-specific phosphodiesterase, putative | 0.0153 | 0.0608 | 0.161 |
Schistosoma mansoni | cytochrome P450 | 0.0039 | 0.0053 | 0.0031 |
Plasmodium falciparum | thymidylate kinase | 0.0149 | 0.0591 | 0.8005 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0213 | 0.0455 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0174 | 0.0709 | 0.6865 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.8527 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1649 | 0.7905 | 0.7907 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0039 | 0.0053 | 0.0102 |
Leishmania major | cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 | 0.0153 | 0.0608 | 0.1513 |
Plasmodium vivax | phosphodiesterase gamma, putative | 0.0153 | 0.0608 | 0.8527 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0153 | 0.0608 | 0.1513 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0116 | 0.0183 |
Schistosoma mansoni | inositol monophosphatase | 0.0117 | 0.0432 | 0.0411 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Plasmodium falciparum | phosphodiesterase gamma, putative | 0.0153 | 0.0608 | 0.8299 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.1103 | 0.524 | 0.5236 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0023 | 0.0029 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0062 | 0.0278 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0117 | 0.0432 | 0.5834 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0153 | 0.0608 | 0.161 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0041 | 0.0062 | 0.004 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0153 | 0.0608 | 0.1513 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0137 | 0.0529 | 0.0508 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0062 | 0.0163 |
Giardia lamblia | Ribonuclease H | 0.0044 | 0.008 | 0.0018 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0039 | 0.0053 | 0.0026 |
Leishmania major | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.005 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0153 | 0.0608 | 0.0588 |
Echinococcus multilocularis | thymidylate synthase | 0.0174 | 0.0709 | 0.0689 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0242 | 0.1046 | 0.1027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0213 | 0.0455 |
Brugia malayi | thymidylate synthase | 0.0174 | 0.0709 | 0.1343 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0149 | 0.0591 | 0.1564 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0149 | 0.0591 | 0.8222 |
Schistosoma mansoni | ap endonuclease | 0.0059 | 0.0149 | 0.0127 |
Trypanosoma cruzi | cAMP phosphodiesterase A, putative | 0.0153 | 0.0608 | 0.1513 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0039 | 0.0053 | 0.0035 |
Echinococcus granulosus | dna polymerase eta | 0.0041 | 0.0062 | 0.0044 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.0163 |
Trichomonas vaginalis | cAMP/cGMP cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0072 | 0.0213 | 0.0456 |
Trypanosoma brucei | 3', 5'-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.161 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0803 | 0.3778 | 1 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0072 | 0.0213 | 0.0456 |
Loa Loa (eye worm) | deoxynucleoside kinase | 0.0072 | 0.0213 | 0.0346 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0039 | 0.0053 | 0.0148 |
Trypanosoma brucei | 3', 5'-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.161 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative | 0.0153 | 0.0608 | 0.115 |
Schistosoma mansoni | intermediate filament proteins | 0.0055 | 0.013 | 0.0109 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.0366 | 0.0602 |
Schistosoma mansoni | thyroid hormone receptor | 0.0156 | 0.0623 | 0.0603 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0059 | 0.0149 | 0.0088 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0052 | 0.0114 | 0.0302 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0213 | 0.0456 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Trypanosoma brucei | unspecified product | 0.0052 | 0.0114 | 0.0302 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.0163 |
Mycobacterium leprae | putative cytochrome p450 | 0.0039 | 0.0053 | 0.0148 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0213 | 0.0456 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0055 | 0.013 | 0.0208 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0117 | 0.0432 | 0.0411 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0039 | 0.0053 | 0.0102 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0039 | 0.0053 | 0.0148 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.0163 |
Schistosoma mansoni | hypothetical protein | 0.0137 | 0.0529 | 0.0508 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Echinococcus multilocularis | high affinity cgmp specific 3' 5' cyclic | 0.0153 | 0.0608 | 0.0588 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0096 | 0.0171 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0803 | 0.3778 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0052 | 0.0114 | 0.0302 |
Toxoplasma gondii | thymidylate kinase | 0.0149 | 0.0591 | 0.0946 |
Schistosoma mansoni | lipoxygenase | 0.0057 | 0.0139 | 0.0117 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0117 | 0.0432 | 0.0415 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0803 | 0.3778 | 1 |
Loa Loa (eye worm) | thymidylate kinase | 0.0149 | 0.0591 | 0.0978 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0174 | 0.0709 | 1 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Leishmania major | hypothetical protein, conserved | 0.0153 | 0.0608 | 0.1513 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0096 | 0.0079 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.1255 | 0.5985 | 0.5981 |
Echinococcus multilocularis | 0.0039 | 0.0053 | 0.0031 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0149 | 0.0591 | 0.5645 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.0591 | 0.057 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Brugia malayi | Pre-SET motif family protein | 0.0229 | 0.0982 | 0.1864 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0039 | 0.0053 | 0.0148 |
Mycobacterium ulcerans | thymidylate kinase | 0.0149 | 0.0591 | 0.8222 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0039 | 0.0053 | 0.0148 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0153 | 0.0608 | 0.115 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.016 | 0.0644 | 0.1035 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0039 | 0.0053 | 0.0102 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0149 | 0.0591 | 0.1564 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Schistosoma mansoni | phosphoglucomutase | 0.0044 | 0.008 | 0.0058 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0059 | 0.0149 | 0.0284 |
Giardia lamblia | hypothetical protein | 0.0153 | 0.0608 | 0.055 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Wolbachia endosymbiont of Brugia malayi | thymidylate kinase | 0.0149 | 0.0591 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0023 | 0.0006 |
Plasmodium falciparum | phosphodiesterase delta, putative | 0.0153 | 0.0608 | 0.8299 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0039 | 0.0053 | 0.0102 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0039 | 0.0053 | 0.0148 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0043 | 0.0114 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.8299 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.0163 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0022 | 0.0005 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.8527 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0043 | 0.0021 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0039 | 0.0053 | 0.0102 |
Echinococcus multilocularis | transfer RNA-Ile | 0.2077 | 0.9992 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0043 | 0.007 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0059 | 0.0149 | 0.0239 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.007 | 0.0206 | 0.0436 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.0062 | 0.0044 |
Schistosoma mansoni | hypothetical protein | 0.0339 | 0.1518 | 0.15 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0153 | 0.0608 | 0.0592 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0174 | 0.0709 | 0.1143 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0104 | 0.0082 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0026 | 0.0038 |
Loa Loa (eye worm) | PDE1B protein | 0.0153 | 0.0608 | 0.1007 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.013 | 0.0208 |
Giardia lamblia | Hypothetical protein | 0.0153 | 0.0608 | 0.055 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Brugia malayi | cytochrome P450 | 0.0039 | 0.0053 | 0.0089 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0153 | 0.0608 | 0.1513 |
Brugia malayi | thymidylate kinase | 0.0149 | 0.0591 | 0.1117 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0064 | 0.0176 | 0.0356 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.005 |
Schistosoma mansoni | lamin | 0.0055 | 0.013 | 0.0109 |
Onchocerca volvulus | 0.0037 | 0.0043 | 0.0176 | |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0043 | 0.007 |
Echinococcus granulosus | high affinity cAMP specific 3'5' cyclic | 0.0153 | 0.0608 | 0.0592 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0242 | 0.1046 | 0.1031 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0039 | 0.0053 | 0.0148 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0059 | 0.0149 | 0.0283 |
Schistosoma mansoni | thyroid hormone receptor | 0.0156 | 0.0623 | 0.0603 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Trypanosoma brucei | cytochrome P450, putative | 0.0066 | 0.0185 | 0.0489 |
Brugia malayi | RNase H family protein | 0.0044 | 0.008 | 0.0141 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.0207 | 0.0383 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0117 | 0.0432 | 0.104 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0039 | 0.0053 | 0.0102 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.1255 | 0.5985 | 0.5981 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0022 | 0.003 |
Echinococcus multilocularis | thymidine kinase | 0.2077 | 0.9992 | 1 |
Brugia malayi | RNase H family protein | 0.0044 | 0.008 | 0.0141 |
Onchocerca volvulus | 0.0037 | 0.0043 | 0.0176 | |
Trypanosoma cruzi | thymidine kinase, putative | 0.0803 | 0.3778 | 1 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0057 | 0.0139 | 0.0122 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0055 | 0.0133 | 0.0239 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0039 | 0.0053 | 0.0148 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0062 | 0.0163 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0059 | 0.0149 | 0.1092 |
Schistosoma mansoni | inositol monophosphatase | 0.0117 | 0.0432 | 0.0411 |
Schistosoma mansoni | hypothetical protein | 0.0339 | 0.1518 | 0.15 |
Onchocerca volvulus | 0.0037 | 0.0043 | 0.0176 | |
Trypanosoma brucei | thymidine kinase | 0.0803 | 0.3778 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0023 | 0.0001 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0043 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0043 | 0.0062 |
Brugia malayi | Deoxynucleoside kinase family protein | 0.0072 | 0.0213 | 0.0395 |
Trypanosoma cruzi | cAMP phosphodiesterase A, putative | 0.0153 | 0.0608 | 0.1513 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0039 | 0.0053 | 0.0102 |
Leishmania major | ribonuclease H1, putative | 0.0044 | 0.008 | 0.0098 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0153 | 0.0608 | 0.115 |
Toxoplasma gondii | ribonuclease HI protein | 0.0044 | 0.008 | 0.0094 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0041 | 0.0062 | 0.0191 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0213 | 0.0456 |
Brugia malayi | hypothetical protein | 0.0242 | 0.1046 | 0.1986 |
Giardia lamblia | Thymidine kinase | 0.0803 | 0.3778 | 0.3739 |
Echinococcus granulosus | lamin | 0.0055 | 0.013 | 0.0113 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0059 | 0.0149 | 0.0394 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.0366 | 0.0688 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0039 | 0.0053 | 0.0102 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.0163 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.1255 | 0.5985 | 0.596 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0153 | 0.0608 | 0.115 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0608 | 0.1007 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0096 | 0.0074 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0059 | 0.0149 | 0.0283 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0022 | 0.0027 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.1103 | 0.524 | 0.5234 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0117 | 0.0432 | 0.0681 |
Leishmania major | hypothetical protein, conserved | 0.0153 | 0.0608 | 0.1513 |
Brugia malayi | intermediate filament protein | 0.0055 | 0.013 | 0.0237 |
Schistosoma mansoni | thymidylate kinase | 0.0149 | 0.0591 | 0.057 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0083 | 0.0266 | 0.0596 |
Echinococcus granulosus | Thymidine kinase 2 mitochondrial | 0.2077 | 0.9992 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.1263 | 0.6022 | 1 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0059 | 0.0149 | 0.0284 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0066 | 0.0185 | 0.0298 |
Leishmania major | cathepsin L-like protease | 0.007 | 0.0206 | 0.0436 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0062 | 0.0278 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0043 | 0.0062 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.0163 |
Brugia malayi | Cytochrome P450 family protein | 0.0039 | 0.0053 | 0.0089 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0153 | 0.0608 | 0.0592 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0022 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0311 | 0.1379 | 0.1361 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0059 | 0.0149 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0062 | 0.0093 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0066 | 0.0185 | 0.0298 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0066 | 0.0185 | 0.2125 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0153 | 0.0608 | 0.0975 |
Leishmania major | cAMP-specific phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0229 | 0.0982 | 0.1631 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.0044 | 0.008 | 0.0507 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0023 | 0.0001 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0104 | 0.0082 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0062 | 0.0163 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Echinococcus granulosus | thymidine kinase | 0.2077 | 0.9992 | 1 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0174 | 0.0709 | 0.1783 |
Treponema pallidum | thymidylate kinase (tmk) | 0.0149 | 0.0591 | 1 |
Echinococcus multilocularis | high affinity cAMP specific 3',5' cyclic | 0.0153 | 0.0608 | 0.0588 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0059 | 0.0149 | 0.0284 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0153 | 0.0608 | 0.115 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0213 | 0.0455 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.0153 | 0.0608 | 0.115 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0043 | 0.0026 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.0116 | 0.0194 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0206 | 0.0545 |
Echinococcus granulosus | high affinity cgmp specific 3' 5' cyclic | 0.0153 | 0.0608 | 0.0592 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0039 | 0.0053 | 0.0102 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0213 | 0.0456 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0039 | 0.0053 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0366 | 0.0602 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.1103 | 0.524 | 1 |
Echinococcus multilocularis | lamin | 0.0055 | 0.013 | 0.0109 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0213 | 0.0456 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0608 | 0.1007 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0043 | 0.0286 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0149 | 0.0591 | 0.1466 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0115 | 0.0422 | 0.0694 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0153 | 0.0608 | 0.0588 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0153 | 0.0608 | 0.1513 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0041 | 0.0062 | 0.0106 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0039 | 0.0053 | 0.0102 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0153 | 0.0608 | 0.161 |
Brugia malayi | Cytochrome P450 family protein | 0.0066 | 0.0185 | 0.0341 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0041 | 0.0062 | 0.005 |
Leishmania major | cathepsin L-like protease | 0.007 | 0.0206 | 0.0436 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0608 | 0.1007 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0213 | 0.0455 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Dose (functional) | = 1.5 mg kg-1 | Compounds were evaluated for phototoxicity no-effect dose in mouse | ChEMBL. | 8385225 |
MIC (functional) | = 0.1 ug ml-1 | Antibacterial activity in vitro against Escherichia coli Vogel | ChEMBL. | 8385225 |
PD50 (functional) | = 3 mg kg-1 | Antibacterial activity against Escherichia coli Vogel after subcutaneous administration in mouse | ChEMBL. | 8385225 |
PD50 (functional) | = 10 mg kg-1 | Antibacterial activity against Escherichia coli Vogel after oral administration in mouse | ChEMBL. | 8385225 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.