Detailed information for compound 1580486

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 563.63 | Formula: C30H25N7O3S
  • H donors: 2 H acceptors: 7 LogP: 4.49 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: OCCCn1cnc2c1nc(C#N)nc2NCc1cccc(c1)c1cc2c(n1S(=O)(=O)c1ccccc1)cccc2
  • InChi: 1S/C30H25N7O3S/c31-18-27-34-29(28-30(35-27)36(20-33-28)14-7-15-38)32-19-21-8-6-10-22(16-21)26-17-23-9-4-5-13-25(23)37(26)41(39,40)24-11-2-1-3-12-24/h1-6,8-13,16-17,20,38H,7,14-15,19H2,(H,32,34,35)
  • InChiKey: ZEWQIKYLLVIMRU-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cathepsin L Starlite/ChEMBL References
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like References
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin L 333 aa 359 aa 30.1 %
Giardia lamblia Cathepsin L precursor cysteine peptidase, Clan CA, family C1, Cathepsin L-like 450 aa 428 aa 21.5 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0315
Onchocerca volvulus 0.0019 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Schistosoma mansoni hypothetical protein 0.015 0.0851 0.0938
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0288 0.0494
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0108 0.0185
Schistosoma mansoni biogenic amine receptor 0.0064 0.0313 0.0345
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.003 0.0098 0.0108
Loa Loa (eye worm) hypothetical protein 0.0105 0.0567 0.0977
Plasmodium falciparum cGMP-specific phosphodiesterase 0.003 0.0098 0.0315
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.0064 0.0313 0.0343
Entamoeba histolytica acyl-coA synthetase, putative 0.0074 0.0371 0.312
Echinococcus multilocularis protein phosphatase 1 catalytic subunit 0.002 0.0034 0.0032
Brugia malayi Papain family cysteine protease containing protein 0.0067 0.0332 0.057
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0019 0.0027 0.0028
Schistosoma mansoni glucose transporter 0.0016 0.0009 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0332 0.2117
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0163 0.0178
Brugia malayi F/Y-rich N-terminus family protein 0.0033 0.0116 0.0198
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.003 0.0098 0.0096
Echinococcus granulosus neuropeptide Y receptor 0.0064 0.0313 0.0343
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.003 0.0098 0.0106
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0108 0.0107
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0132 0.0844
Entamoeba histolytica cdc48-like protein, putative 0.0029 0.0086 0.055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Brugia malayi hypothetical protein 0.0019 0.0025 0.0042
Onchocerca volvulus 0.0064 0.0313 0.0538
Echinococcus granulosus small conductance calcium activated potassium 0.0502 0.3076 0.3389
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0062 0.0295 0.0323
Brugia malayi G protein-coupled receptor F59B2.13 0.0064 0.0313 0.0538
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0014 0.0013
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.003 0.0098 0.2834
Schistosoma mansoni opsin-like receptor 0.0064 0.0313 0.0345
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.004 0.0161 0.1029
Schistosoma mansoni microtubule-associated protein tau 0.1452 0.9073 1
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0042 0.0153
Schistosoma mansoni coup transcription factor 0.0032 0.0108 0.0119
Brugia malayi hypothetical protein 0.0064 0.0313 0.0538
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0054 0.0257
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0191 0.0639
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0064 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0066 0.0323 0.206
Echinococcus granulosus neuropeptides capa receptor 0.0064 0.0313 0.0343
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0108 0.0118
Echinococcus multilocularis fmrfamide receptor 0.0064 0.0313 0.0312
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0164 0.094 0.0939
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0332 0.1131
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0125 0.0902
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0074 0.0371 0.2793
Echinococcus granulosus PHD finger protein rhinoceros 0.0033 0.0114 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0098 0.0312
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0019 0.0025 0.0042
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0108 0.0185
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.002 0.0034 0.0032
Echinococcus granulosus survival motor neuron protein 1 0.0734 0.4539 0.5002
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0129 0.0128
Onchocerca volvulus 0.0064 0.0313 0.0538
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0127 0.0633
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.0009 0.0008
Schistosoma mansoni rab6-interacting 0.0022 0.0047 0.0052
Schistosoma mansoni glucose transport protein 0.0116 0.0635 0.07
Echinococcus granulosus solute carrier family 22 0.0016 0.0009 0.0008
Brugia malayi major facilitator superfamily protein 0.0016 0.0009 0.0012
Echinococcus granulosus expressed conserved protein 0.0182 0.1057 0.1164
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0116 0.0635 0.0634
Giardia lamblia Lysyl-tRNA synthetase 0.0026 0.0069 0.1918
Echinococcus granulosus rhodopsin orphan GPCR 0.0064 0.0313 0.0343
Echinococcus granulosus methyl CpG binding domain protein 2 0.0318 0.1917 0.2111
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.043 0.0473
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0108 0.0185
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0067 0.0332 0.033
Leishmania major ion transport protein-like protein 0.0019 0.0025 0.0163
Brugia malayi nuclear hormone receptor 0.0032 0.0108 0.0185
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0149 0.0845 0.093
Onchocerca volvulus 0.0016 0.0009 0.0012
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0323 0.206
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0127 0.0138
Loa Loa (eye worm) hypothetical protein 0.0074 0.0371 0.0638
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0127 0.0217
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0042 0.0668
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0019 0.0025 0.0042
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0019 0.0027 0.0026
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0159 0.0908 0.5799
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.003 0.0098 0.0108
Loa Loa (eye worm) hypothetical protein 0.0194 0.1132 0.1952
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0318 0.1917 0.1915
Echinococcus granulosus nmda type glutamate receptor 0.0019 0.0027 0.0028
Brugia malayi Serine/threonine protein phosphatase PP1-beta catalytic subunit 0.002 0.0034 0.0056
Echinococcus granulosus sterol regulatory element binding protein 0.0083 0.0432 0.0475
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.004 0.0161 0.1029
Mycobacterium ulcerans hypothetical protein 0.0074 0.0371 0.1956
Entamoeba histolytica hypothetical protein 0.0041 0.0163 0.1244
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.1319 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Onchocerca volvulus 0.0016 0.0009 0.0012
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Brugia malayi major facilitator superfamily protein 0.0016 0.0009 0.0012
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0133 0.3957
Schistosoma mansoni histamine h1 receptor 0.0064 0.0313 0.0345
Loa Loa (eye worm) hypothetical protein 0.0045 0.019 0.0325
Echinococcus granulosus neuropeptides capa receptor 0.0064 0.0313 0.0343
Schistosoma mansoni biogenic amine receptor 0.0064 0.0313 0.0345
Loa Loa (eye worm) jmjC domain-containing protein 0.0068 0.0336 0.0578
Loa Loa (eye worm) oxidoreductase 0.0022 0.0042 0.0071
Loa Loa (eye worm) hypothetical protein 0.0022 0.0042 0.0071
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0003 0.0003
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0127 0.0641
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0158 0.0905 0.0903
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0035 0.0125 0.0138
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Mycobacterium tuberculosis Conserved protein 0.0035 0.0127 0.0943
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0217
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.003 0.0098 0.0106
Plasmodium falciparum cysteine proteinase falcipain 1 0.0035 0.0125 0.0407
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0001 0.0002
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0042 0.0071
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.003 0.0098 0.0623
Onchocerca volvulus 0.0019 0.0025 0.0042
Schistosoma mansoni hypothetical protein 0.0049 0.0215 0.0237
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0064 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.0067 0.0328 0.0564
Schistosoma mansoni single-minded 0.0069 0.034 0.0375
Echinococcus granulosus solute carrier family 22 0.0016 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Onchocerca volvulus 0.0019 0.0025 0.0042
Plasmodium vivax sugar transporter, putative 0.0016 0.0009 0.0018
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0013 0.0014
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Schistosoma mansoni hypothetical protein 0.0064 0.0313 0.0345
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0047 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0064 0.0313 0.0312
Echinococcus granulosus microtubule associated protein 2 0.1452 0.9073 1
Entamoeba histolytica hypothetical protein 0.0026 0.0069 0.0392
Loa Loa (eye worm) TWK-28 protein 0.0019 0.0025 0.0042
Onchocerca volvulus 0.0064 0.0313 0.0538
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0023 0.0155
Entamoeba histolytica hypothetical protein 0.0041 0.0163 0.1244
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0108 0.0185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0108 0.0185
Onchocerca volvulus 0.0035 0.0127 0.0217
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.0047 0.0078
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0042 0.0183
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0127 0.0943
Brugia malayi hypothetical protein 0.0064 0.0313 0.0538
Loa Loa (eye worm) sugar transporter 0.0016 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0371 0.2366
Loa Loa (eye worm) PDE1B protein 0.0771 0.477 0.8238
Leishmania major cathepsin L-like protease 0.0181 0.1049 0.6697
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Brugia malayi hypothetical protein 0.0018 0.0019 0.003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0127 0.014
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-beta catalytic subunit 0.002 0.0034 0.0056
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0042 0.0183
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus multilocularis sex peptide receptor 0.0064 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0035 0.0125 0.0136
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Brugia malayi hypothetical protein 0.0064 0.0313 0.0538
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0003 0.002
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.003 0.0098 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0098 0.0312
Echinococcus multilocularis rhodopsin orphan GPCR 0.0064 0.0313 0.0312
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0035 0.0125 0.0138
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Echinococcus multilocularis neuropeptide Y receptor 0.0064 0.0313 0.0312
Echinococcus multilocularis somatostatin receptor 0.0064 0.0313 0.0312
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.003 0.0098 0.0106
Echinococcus multilocularis cpg binding protein 0.0066 0.0321 0.032
Echinococcus granulosus Desert hedgehog protein 0.0207 0.1213 0.1336
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0108 0.0119
Loa Loa (eye worm) G-protein coupled receptor 0.0064 0.0313 0.0538
Echinococcus multilocularis GPCR, family 2 0.0049 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0047 0.0079
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0049 0.0141
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0019 0.0025 0.0042
Echinococcus multilocularis serine:threonine protein phosphatase PP1 beta 0.002 0.0034 0.0032
Brugia malayi Bromodomain containing protein 0.0035 0.0129 0.022
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0127 0.0812
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0023 0.005 0.0882
Giardia lamblia PHD finger protein 15 0.0033 0.0114 0.3366
Echinococcus granulosus netrin receptor unc 5 0.0067 0.0326 0.0358
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0064 0.0313 0.0343
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0019 0.0025 0.0042
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0323 0.11
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0016 0.0009 0.0055
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0062 0.0295 0.0323
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0043 0.0179 0.5419
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0066 0.0323 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0067 0.0326 0.0561
Trypanosoma brucei cAMP-specific phosphodiesterase 0.003 0.0098 0.0623
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0179 0.1037 0.1143
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0013 0.0013
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0263 0.1566 0.5213
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.0047 0.0298
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0286 0.1441
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0129 0.0221
Schistosoma mansoni cathepsin F (C01 family) 0.0067 0.0332 0.0365
Echinococcus granulosus neuropeptide s receptor 0.0585 0.3599 0.3966
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0197 0.1151 0.1268
Onchocerca volvulus 0.0067 0.0332 0.057
Trypanosoma cruzi ion transport protein, putative 0.0019 0.0025 0.0163
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0042 0.0131
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0042 0.0071
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0047 0.0146
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0016 0.0009 0.0007
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0066 0.0323 0.206
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0042 0.0183
Schistosoma mansoni sugar transporter 0.0016 0.0009 0.0009
Giardia lamblia Prolyl-tRNA synthetase 0.0035 0.0125 0.3702
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0042 0.0071
Schistosoma mansoni neuropeptide F-like receptor 0.0064 0.0313 0.0345
Echinococcus granulosus rhodopsin orphan GPCR 0.0064 0.0313 0.0343
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0234 0.1756
Schistosoma mansoni hypothetical protein 0.0064 0.0313 0.0345
Brugia malayi hypothetical protein 0.0932 0.579 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0133 0.0435
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.003 0.0098 0.0108
Loa Loa (eye worm) TYRA-2 protein 0.0064 0.0313 0.0538
Loa Loa (eye worm) hypothetical protein 0.0932 0.579 1
Toxoplasma gondii ion channel protein 0.0019 0.0025 0.0114
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0108 0.0185
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0019 0.0025 0.0163
Leishmania major hypothetical protein, conserved 0.0016 0.0009 0.0055
Brugia malayi larval opioid receptor 0.0064 0.0313 0.0538
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0062 0.0295 0.0293
Trypanosoma cruzi cysteine proteinase, putative 0.0035 0.0125 0.08
Echinococcus granulosus g protein coupled receptor 0.0064 0.0313 0.0343
Schistosoma mansoni hypothetical protein 0.0049 0.0215 0.0237
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.002
Trichomonas vaginalis set domain proteins, putative 0.0468 0.2863 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus multilocularis neuropeptide Y receptor 0.0064 0.0313 0.0312
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0066 0.0323 0.206
Echinococcus multilocularis twik family of potassium channels 0.0019 0.0025 0.0024
Echinococcus granulosus intestinal type alkaline phosphatase 0.0158 0.0905 0.0996
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0263 0.1566 0.7961
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0019 0.0036
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0019 0.0025 0.0163
Plasmodium vivax potassium channel, putative 0.0019 0.0025 0.0075
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0042 0.0047
Schistosoma mansoni protein phosphatase type 1 0.002 0.0034 0.0037
Echinococcus granulosus Niemann Pick C1 protein 0.0277 0.1657 0.1826
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0043 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0127 0.0415
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Schistosoma mansoni opsin-like receptor 0.0064 0.0313 0.0345
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0042 0.0183
Onchocerca volvulus 0.0064 0.0313 0.0538
Trypanosoma cruzi cruzipain precursor, putative 0.0022 0.0047 0.0298
Plasmodium vivax cell division cycle protein 48 homologue, putative 0.0029 0.0086 0.0277
Schistosoma mansoni lipoxygenase 0.0133 0.0748 0.0825
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0009 0.0055
Brugia malayi bHLH-PAS transcription factor 0.0051 0.0228 0.0391
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.003 0.0098 0.0108
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0019 0.0036
Echinococcus multilocularis protein dispatched 1 0.0095 0.0506 0.0505
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0127 0.0125
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.002 0.0034 0.0036
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0108 0.0119
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0098 0.0623
Plasmodium vivax unspecified product 0.0022 0.0047 0.0146
Brugia malayi hypothetical protein 0.0022 0.0047 0.0079
Brugia malayi hypothetical protein 0.0064 0.0313 0.0538
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0016 0.0009 0.0042
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.0009 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0295 0.0325
Leishmania major serine/threonine protein phosphatase catalytic subunit, putative 0.002 0.0034 0.0216
Brugia malayi hypothetical protein 0.0734 0.4539 0.7838
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0018 0.0023 0.0023
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.002 0.0035 0.0224
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0129 0.0141
Schistosoma mansoni patched 1 0.0083 0.0432 0.0476
Toxoplasma gondii serine/threonine phosophatase PP1 0.002 0.0034 0.0156
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0043 0.0179 0.0307
Echinococcus granulosus zinc finger protein 0.0022 0.0048 0.0051
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0054 0.1139
Schistosoma mansoni hypothetical protein 0.0502 0.3076 0.339
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0234 0.1756
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Loa Loa (eye worm) inositol-1 0.0036 0.0133 0.0227
Loa Loa (eye worm) hypothetical protein 0.0194 0.1134 0.1956
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0064 0.0313 0.0538
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0127 0.0812
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0054 0.0257
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0127 0.0812
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0116 0.0635 0.0634
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0042 0.0183
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0108 0.0118
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0332 0.1131
Onchocerca volvulus Huntingtin homolog 0.0122 0.0679 0.117
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0064 0.0313 0.0538
Onchocerca volvulus 0.0016 0.0009 0.0012
Echinococcus multilocularis solute carrier family 22 0.0016 0.0009 0.0007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0042 0.0299
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Echinococcus multilocularis PHD finger protein rhinoceros 0.0033 0.0114 0.0113
Echinococcus granulosus Sugar transporter ERD6 protein 0.0016 0.0009 0.0008
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0003 0.002
Plasmodium falciparum cell division cycle protein 48 homologue, putative 0.0029 0.0086 0.0277
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Onchocerca volvulus 0.0064 0.0313 0.0538
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0371 0.0638
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0108 0.0107
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0042 0.02
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0042 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0042 0.0183
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Schistosoma mansoni glutamate receptor kainate 0.0052 0.0233 0.0256
Loa Loa (eye worm) hypothetical protein 0.0045 0.0191 0.0327
Trypanosoma brucei glucose transporter, putative 0.0036 0.0132 0.0844
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Schistosoma mansoni alkaline phosphatase 0.0158 0.0905 0.0997
Entamoeba histolytica cysteine proteinase, putative 0.0045 0.0191 0.1495
Echinococcus multilocularis rhodopsin orphan GPCR 0.0064 0.0313 0.0312
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0771 0.477 0.5258
Leishmania major potassium channel subunit-like protein 0.0019 0.0025 0.0163
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0127 0.0943
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0025 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.003 0.0098 0.0312
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Schistosoma mansoni glutaminase 0.0309 0.1859 0.2049
Brugia malayi Cathepsin L-like cysteine proteinase 0.0045 0.0191 0.0327
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.003 0.0098 0.0166
Giardia lamblia AAA family ATPase 0.0018 0.002 0.0355
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Echinococcus multilocularis alkaline phosphatase 0.0158 0.0905 0.0903
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0044 0.0313
Entamoeba histolytica hypothetical protein 0.0041 0.0163 0.1244
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.0635 0.0699
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0023 0.005 0.0144
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Loa Loa (eye worm) hypothetical protein 0.0131 0.0731 0.1261
Schistosoma mansoni protein kinase 0.0035 0.0129 0.0143
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0108 0.0185
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0026 0.0069 0.0439
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0019 0.0036
Brugia malayi Sugar transporter family protein 0.0116 0.0635 0.1095
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Brugia malayi hypothetical protein 0.0017 0.0013 0.002
Schistosoma mansoni methyl-cpg binding protein mbd 0.0256 0.152 0.1675
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.003 0.0098 0.0623
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.002
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0263 0.1566 1
Echinococcus multilocularis glutamate receptor 2 0.0139 0.0783 0.0781
Echinococcus multilocularis potassium channel subfamily K 8 0.0019 0.0025 0.0024
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0127 0.0943
Plasmodium falciparum calcium-dependent protein kinase 5 0.0035 0.0129 0.0422
Schistosoma mansoni loxhd1 0.0022 0.0047 0.0052
Echinococcus granulosus protein phosphatase 1 catalytic subunit 0.002 0.0034 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0332 0.1131
Brugia malayi follicle stimulating hormone receptor 0.0064 0.0313 0.0538
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0132 0.0433
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0066 0.0323 0.1066
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0127 0.0943
Brugia malayi hypothetical protein 0.0022 0.0047 0.0079
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0371 0.2366
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0295 0.0325
Brugia malayi G-protein coupled receptor 0.0064 0.0313 0.0538
Brugia malayi jmjC domain containing protein 0.0045 0.0192 0.0329
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0064 0.0313 0.0312
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0025 0.0028
Schistosoma mansoni nuclear receptor 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Schistosoma mansoni opsin-like receptor 0.0064 0.0313 0.0345
Loa Loa (eye worm) hypothetical protein 0.0055 0.0253 0.0435
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0127 0.0943
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0019 0.0036
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0069 0.0076
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0019 0.0025 0.0163
Brugia malayi ecdysteroid receptor 0.0032 0.0108 0.0185
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus multilocularis NMDA receptor 0.0019 0.0027 0.0026
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Onchocerca volvulus 0.0016 0.0009 0.0012
Leishmania major glucose transporter, lmgt1 0.0036 0.0132 0.0844
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0042 0.0271
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0108 0.0185
Brugia malayi Doublecortin family protein 0.0022 0.0047 0.0079
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0771 0.477 0.5257
Onchocerca volvulus 0.0064 0.0313 0.0538
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0098 0.0623
Schistosoma mansoni protein kinase 0.0035 0.0129 0.0143
Brugia malayi vesicle-fusing ATPase 0.0018 0.0017 0.0028
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0064 0.0313 0.0345
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0042 0.0071
Brugia malayi hypothetical protein 0.0171 0.0985 0.17
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0108 0.0185
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Onchocerca volvulus 0.0064 0.0313 0.0538
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Plasmodium falciparum calcium-dependent protein kinase 4 0.0035 0.0129 0.0422
Loa Loa (eye worm) RNA binding protein 0.0062 0.0295 0.0507
Schistosoma mansoni amine GPCR 0.0064 0.0313 0.0345
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Schistosoma mansoni hypothetical protein 0.0022 0.0047 0.0052
Echinococcus multilocularis cathepsin L cysteine protease 0.0067 0.0332 0.033
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0215 0.0214
Brugia malayi glutaminase DH11.1 0.0309 0.1859 0.3209
Echinococcus granulosus rhodopsin orphan GPCR 0.0064 0.0313 0.0343
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0035 0.0129 0.0141
Brugia malayi hypothetical protein 0.0016 0.0009 0.0012
Onchocerca volvulus 0.0022 0.0042 0.0071
Brugia malayi lysyl-tRNA synthetase 0.0026 0.0069 0.0116
Echinococcus granulosus calcium dependent protein kinase 0.0033 0.0116 0.0126
Echinococcus multilocularis glutamate receptor 2 0.0149 0.0845 0.0843
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0042 0.0183
Loa Loa (eye worm) hypothetical protein 0.003 0.0098 0.0166
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0158 0.0905 0.0903
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0035 0.0129 0.0422
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0042 0.0271
Echinococcus multilocularis allatostatin A receptor 0.0064 0.0313 0.0312
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.043 0.0429
Onchocerca volvulus Huntingtin homolog 0.0122 0.0679 0.117
Brugia malayi MBD3 protein 0.03 0.1799 0.3105
Loa Loa (eye worm) hypothetical protein 0.003 0.0098 0.0166
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0315
Brugia malayi hypothetical protein 0.0064 0.0313 0.0538
Echinococcus multilocularis jumonji domain containing protein 0.0046 0.0196 0.0194
Leishmania major cathepsin L-like protease 0.0067 0.0332 0.2117
Onchocerca volvulus 0.015 0.0851 0.1468
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0043 0.0179 0.1141
Onchocerca volvulus 0.0016 0.0009 0.0012
Brugia malayi Protein kinase domain containing protein 0.0069 0.034 0.0585
Loa Loa (eye worm) TWK-7 protein 0.0019 0.0025 0.0042
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0149 0.0845 0.0843
Echinococcus granulosus g protein coupled receptor 0.0064 0.0313 0.0343
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.0371 0.312
Mycobacterium ulcerans transmembrane cation transporter 0.0019 0.0025 0.0091
Loa Loa (eye worm) hypothetical protein 0.004 0.0156 0.0267
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.0635 0.0699
Brugia malayi Bromodomain containing protein 0.0179 0.1034 0.1785
Echinococcus granulosus glutamate receptor 1 0.0087 0.0456 0.0501
Echinococcus granulosus tm gpcr rhodopsin 0.0064 0.0313 0.0343
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0064 0.0313 0.0345
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0108 0.0118
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0042 0.0299
Leishmania major calcium/potassium channel (CAKC), putative 0.0019 0.0025 0.0163
Leishmania major hypothetical protein, conserved 0.0019 0.0025 0.0163
Schistosoma mansoni bromodomain containing protein 0.0065 0.0316 0.0349
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Schistosoma mansoni sugar transporter 0.0016 0.0009 0.0009
Mycobacterium ulcerans lipase LipD 0.0035 0.0127 0.0641
Loa Loa (eye worm) hypothetical protein 0.0022 0.0047 0.0078
Schistosoma mansoni sugar transporter 0.0016 0.0009 0.0009
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0295 0.0507
Loa Loa (eye worm) cysteine protease 0.0067 0.0332 0.057
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0003 0.002
Echinococcus multilocularis peregrin 0.0035 0.0129 0.0127
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0042 0.0041
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0018 0.0019 0.0121
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0066 0.0323 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0132 0.0433
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0064 0.0313 0.0345
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0013 0.002
Echinococcus granulosus tm gpcr rhodopsin 0.0064 0.0313 0.0343
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.0635 0.0699
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Plasmodium vivax vivapain-3 0.0035 0.0125 0.0407
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0019 0.0036
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0042 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0064 0.0313 0.0343
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0127 0.014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0064 0.0313 0.0345
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0371 0.0638
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0064 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.0045 0.0191 0.0327
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Echinococcus granulosus Niemann Pick C1 protein 0.0194 0.1132 0.1246
Schistosoma mansoni hypothetical protein 0.0064 0.0313 0.0345
Brugia malayi Glutamate receptor 2 precursor 0.0139 0.0783 0.135
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0108 0.0119
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0054 0.1431
Schistosoma mansoni glucose transport protein 0.0116 0.0635 0.07
Schistosoma mansoni amine GPCR 0.0064 0.0313 0.0345
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0066 0.0323 0.206
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0133 0.0971
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0108 0.0119
Schistosoma mansoni cathepsin F (C01 family) 0.0045 0.0191 0.021
Trypanosoma cruzi cysteine peptidase, putative 0.0181 0.1049 0.6697
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.0371 0.312
Echinococcus granulosus Protein patched homolog 1 0.0083 0.0432 0.0475
Echinococcus multilocularis cysteine protease 0.0067 0.0332 0.033
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0371 0.1956
Schistosoma mansoni glutamate receptor AMPA 0.0052 0.0233 0.0256
Echinococcus multilocularis g protein coupled receptor 0.0064 0.0313 0.0312
Echinococcus granulosus cathepsin L cysteine protease 0.0035 0.0125 0.0136
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0263 0.1566 1
Brugia malayi PHD-finger family protein 0.0016 0.0008 0.0011
Echinococcus granulosus glutamate receptor subunit protein glur 0.0106 0.0577 0.0634
Loa Loa (eye worm) hypothetical protein 0.0043 0.0179 0.0307
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0098 0.0623
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0066 0.0323 0.0356
Schistosoma mansoni protein phosphatase type 1 0.002 0.0034 0.0037
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0133 0.0848
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Echinococcus granulosus 7TM GPCR rhodopsin 0.0064 0.0313 0.0343
Loa Loa (eye worm) hypothetical protein 0.0179 0.1037 0.1789
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0014 0.0014
Leishmania major cAMP-specific phosphodiesterase, putative 0.003 0.0098 0.0623
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0263 0.1566 0.1565
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0132 0.0433
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0047 0.0045
Echinococcus granulosus glutamate NMDA receptor subunit 0.0052 0.0233 0.0255
Brugia malayi hypothetical protein 0.0016 0.0009 0.0012
Plasmodium falciparum hexose transporter 0.0116 0.0635 0.2109
Onchocerca volvulus Alhambra homolog 0.0033 0.0114 0.0195
Echinococcus granulosus neuropeptide receptor 0.0064 0.0313 0.0343
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus Ankyrin 0.0067 0.0328 0.036
Echinococcus granulosus serotonin receptor 0.0064 0.0313 0.0343
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0054 0.0984
Trypanosoma brucei glucose transporter, putative 0.0036 0.0132 0.0844
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0022 0.0044 0.0313
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0127 0.0943
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0127 0.0217
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0067 0.0332 0.057
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.003 0.0098 0.0096
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0009 0.0012
Onchocerca volvulus 0.0035 0.0127 0.0217
Onchocerca volvulus 0.0932 0.579 1
Toxoplasma gondii sugar transporter ST1 0.0016 0.0009 0.0028
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0163 0.018
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0371 0.2366
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Brugia malayi beta-lactamase family protein 0.0035 0.0127 0.0217
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus multilocularis zinc finger protein 0.0022 0.0048 0.0047
Brugia malayi steroid hormone receptor 0.0032 0.0108 0.0185
Toxoplasma gondii transporter, major facilitator family protein 0.0016 0.0009 0.0028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0064 0.0313 0.0312
Schistosoma mansoni ATP-binding cassette transporter 0.0052 0.0233 0.0256
Brugia malayi Cathepsin L-like precursor 0.0045 0.0191 0.0327
Plasmodium vivax serine/threonine protein phosphatase PP1, putative 0.002 0.0034 0.0102
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0064 0.0313 0.0312
Echinococcus multilocularis hedgehog 0.0207 0.1213 0.1212
Onchocerca volvulus Transitional endoplasmic reticulum ATPase homolog 0.003 0.0096 0.0163
Brugia malayi G protein-coupled receptor 0.0064 0.0313 0.0538
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0771 0.477 0.8238
Toxoplasma gondii sugar transporter ST3 0.0016 0.0009 0.0028
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.003 0.0098 0.0096
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0323 0.11
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0064 0.0313 0.0345
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0098 0.0623
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0108 0.0185
Brugia malayi RE15519p 0.0064 0.0313 0.0538
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0064 0.0313 0.0345
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Plasmodium falciparum phosphodiesterase gamma, putative 0.003 0.0098 0.0315
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0042 0.0119
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.004 0.0161 0.1029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0064 0.0313 0.0345
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0013 0.002
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Loa Loa (eye worm) beta-lactamase 0.0035 0.0127 0.0217
Brugia malayi Melatonin receptor type 1A 0.0064 0.0313 0.0538
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Schistosoma mansoni amine GPCR 0.0064 0.0313 0.0345
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0116
Brugia malayi Inositol-1 0.0036 0.0133 0.0227
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0047 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0163 0.0162
Echinococcus multilocularis protein patched 0.0083 0.0432 0.0431
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0066 0.0323 0.206
Echinococcus multilocularis rhodopsin orphan GPCR 0.0064 0.0313 0.0312
Brugia malayi putative neuropeptide receptor 0.0064 0.0313 0.0538
Schistosoma mansoni cathepsin F (C01 family) 0.0067 0.0332 0.0365
Loa Loa (eye worm) MBD3 protein 0.03 0.1799 0.3105
Trypanosoma brucei protein phosphatase 1, putative 0.002 0.0034 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.003 0.0098 0.0108
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0108 0.0119
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0025 0.0059
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0019 0.0025 0.0042
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0074 0.0371 0.2793
Echinococcus multilocularis glutamate receptor 4 0.0087 0.0456 0.0455
Echinococcus multilocularis microtubule associated protein 2 0.1452 0.9073 0.9073
Onchocerca volvulus 0.0469 0.2865 0.4946
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0132 0.0433
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0003 0.0002
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0263 0.1566 0.1725
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0108 0.0185
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0127 0.0126
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.003 0.0098 0.0166
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.003 0.0098 0.0312
Schistosoma mansoni zinc finger protein 0.0022 0.0048 0.0053
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0062 0.0295 0.0293
Plasmodium falciparum calcium-dependent protein kinase 1 0.0035 0.0129 0.0422
Onchocerca volvulus 0.0148 0.084 0.145
Schistosoma mansoni neuropeptide receptor 0.0064 0.0313 0.0345
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus g protein coupled receptor 0.0064 0.0313 0.0343
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0029 0.0086 0.0095
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0323 0.11
Echinococcus granulosus twik family of potassium channels 0.0019 0.0025 0.0026
Schistosoma mansoni calcium-activated potassium channel 0.0019 0.0025 0.0028
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0019 0.0025 0.0042
Onchocerca volvulus 0.0064 0.0313 0.0538
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0639 0.1102
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0192 0.0211
Brugia malayi hypothetical protein 0.0122 0.0679 0.117
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0047 0.005
Toxoplasma gondii sugar transporter ST2 0.0016 0.0009 0.0028
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Toxoplasma gondii transitional endoplasmic reticulum ATPase, putative 0.0018 0.002 0.0085
Onchocerca volvulus 0.0067 0.0332 0.057
Onchocerca volvulus Cathepsin F homolog 0.0067 0.0332 0.057
Echinococcus multilocularis dro:myosuppressin receptor 0.0064 0.0313 0.0312
Echinococcus multilocularis dnaJ subfamily B 0.0861 0.5339 0.5339
Trypanosoma brucei glucose transporter 2A 0.0036 0.0132 0.0844
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.002 0.0035 0.0224
Trichomonas vaginalis bsu-protein phosphatase, putative 0.002 0.0034 0.0088
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0047 0.005
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0042 0.0299
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Brugia malayi Cam kinase protein 1 0.0035 0.0129 0.0221
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0042 0.0299
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0047 0.0045
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0019 0.0025 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0035 0.0125 0.08
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0026 0.0069 0.0211
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0066 0.0323 0.1066
Schistosoma mansoni hypothetical protein 0.008 0.0413 0.0455
Schistosoma mansoni sugar transporter 0.0016 0.0009 0.0009
Echinococcus granulosus cpg binding protein 0.0066 0.0321 0.0352
Loa Loa (eye worm) G-protein coupled receptor 0.0064 0.0313 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0125 0.0409
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0217
Onchocerca volvulus 0.0016 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.003 0.0098 0.0108
Echinococcus multilocularis glutamate receptor 2 0.013 0.0724 0.0723
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0064 0.0313 0.0538
Leishmania major hypothetical protein, conserved 0.003 0.0098 0.0623
Brugia malayi Serine/threonine protein phosphatase F56C9.1 in chromosomeIII 0.002 0.0034 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0019 0.0025 0.0026
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0315
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0263 0.1566 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.004 0.0161 0.1029
Brugia malayi Cathepsin L-like precursor 0.0067 0.0332 0.057
Loa Loa (eye worm) glutamate receptor 1 0.0139 0.0783 0.135
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0035 0.0125 0.0898
Brugia malayi nuclear receptor RXR 0.0017 0.0013 0.002
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0064 0.0313 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0067 0.0332 0.1131
Loa Loa (eye worm) hypothetical protein 0.0022 0.0047 0.0079
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0054 0.0243
Loa Loa (eye worm) hypothetical protein 0.0035 0.0125 0.0213
Brugia malayi ORL1-like opioid receptor 0.0064 0.0313 0.0538
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0295 0.0325
Schistosoma mansoni hypothetical protein 0.0064 0.0313 0.0345
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0019 0.0025 0.0042
Echinococcus multilocularis cathepsin L 0.0035 0.0125 0.0124
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0129 0.0141
Onchocerca volvulus 0.0064 0.0313 0.0538
Entamoeba histolytica cysteine proteinase 2 0.0035 0.0125 0.0902
Schistosoma mansoni cathepsin s 0.0022 0.0047 0.0051
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0042 0.0271
Brugia malayi Niemann-Pick C1 protein precursor 0.0194 0.1132 0.1952
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0323 0.206
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.002 0.0033 0.021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0064 0.0313 0.0345
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0132 0.0433
Onchocerca volvulus 0.0019 0.0025 0.0042
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0016 0.0009 0.0042
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0133 0.0748 0.0747
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0108 0.0118
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0018 0.0019 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0035 0.0125 0.08
Schistosoma mansoni glutamate receptor AMPA 0.0052 0.0233 0.0256
Giardia lamblia Hypothetical protein 0.0019 0.0025 0.0537
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.002
Echinococcus granulosus fmrfamide receptor 0.0064 0.0313 0.0343
Loa Loa (eye worm) hypothetical protein 0.0122 0.0679 0.117
Brugia malayi hypothetical protein 0.0041 0.0163 0.0279
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0074 0.0371 0.1956
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0043 0.0179 0.0597
Schistosoma mansoni calcium-activated potassium channel 0.0502 0.3076 0.339
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0133 0.0131
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0074 0.0371 0.1956
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.003 0.0098 0.0166
Onchocerca volvulus 0.0016 0.0009 0.0012
Plasmodium vivax lysine--tRNA ligase, putative 0.0026 0.0069 0.0219
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0052 0.0233 0.0231
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0064 0.0313 0.0345
Trichomonas vaginalis bsu-protein phosphatase, putative 0.002 0.0034 0.0088
Loa Loa (eye worm) hypothetical protein 0.0148 0.084 0.145
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Plasmodium vivax unspecified product 0.0035 0.0125 0.0407
Schistosoma mansoni aryl hydrocarbon receptor 0.02 0.1166 0.1285
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.002 0.0033 0.021
Schistosoma mansoni myosin xvIII 0.0064 0.0313 0.0345
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0133 0.0435
Leishmania major protein kinase, putative 0.0035 0.0129 0.0826
Schistosoma mansoni polycystin 1-related 0.0022 0.0047 0.0052
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0042 0.0299
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0003 0.002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0217
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0264 0.0289
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0127 0.0943
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.0129 0.0423
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0127 0.0415
Brugia malayi Sugar transporter family protein 0.0016 0.0009 0.0012
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0066 0.0323 0.1628
Trypanosoma cruzi Valosin-containing protein, putative 0.0029 0.0086 0.0551
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.003 0.0098 0.0106
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0026 0.0069 0.0439
Leishmania major cathepsin L-like protease 0.0067 0.0332 0.2117
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0064 0.0313 0.0345
Brugia malayi hypothetical protein 0.0064 0.0313 0.0538
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0064 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Brugia malayi isocitrate dehydrogenase 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0011
Schistosoma mansoni lipoxygenase 0.0093 0.0495 0.0546
Brugia malayi putative neuropeptide receptor NPR1 0.0064 0.0313 0.0538
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0043 0.0179 0.1141
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0067 0.0332 0.057
Loa Loa (eye worm) hypothetical protein 0.0074 0.0371 0.0638
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0042 0.0119
Echinococcus granulosus solute carrier family 22 0.0016 0.0009 0.0008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0155 0.0883 0.1522
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.003 0.0098 0.0166
Brugia malayi Pre-SET motif family protein 0.0412 0.2505 0.4325
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0114 0.0566
Schistosoma mansoni biogenic amine (5HT) receptor 0.0064 0.0313 0.0345
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0043 0.0179 0.0597
Echinococcus multilocularis transitional endoplasmic reticulum atpase 0.003 0.0096 0.0095
Loa Loa (eye worm) hypothetical protein 0.0184 0.1067 0.1842
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0158 0.0905 0.0996
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0033 0.0114 0.0126
Schistosoma mansoni hypothetical protein 0.008 0.0413 0.0455
Echinococcus granulosus histone lysine methyltransferase setb 0.0179 0.1037 0.1141
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.002 0.0033 0.021
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0132 0.0844
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Entamoeba histolytica cysteine protease, putative 0.0067 0.0332 0.2767
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0127 0.0641
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0066 0.0323 0.1697
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.002 0.0035 0.0224
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0067 0.0326 0.0561
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0064 0.0313 0.0345
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Onchocerca volvulus 0.0016 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0028
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0074 0.0371 0.1956
Onchocerca volvulus 0.0064 0.0313 0.0538
Brugia malayi CXXC zinc finger family protein 0.006 0.0288 0.0494
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0332 0.1131
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0046 0.0194 0.0332
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Trypanosoma brucei glucose transporter, putative 0.0036 0.0132 0.0844
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.004 0.0161 0.0805
Onchocerca volvulus 0.0019 0.0025 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0098 0.0623
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0019 0.0036
Echinococcus multilocularis neuropeptide FF receptor 2 0.0064 0.0313 0.0312
Brugia malayi Dopamine receptor protein 1 0.0064 0.0313 0.0538
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0035 0.0129 0.0644
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Brugia malayi hypothetical protein 0.0064 0.0313 0.0538
Schistosoma mansoni hypothetical protein 0.0033 0.0114 0.0126
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0042 0.0668
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0064 0.0313 0.0538
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0055 0.0253 0.1901
Schistosoma mansoni inositol monophosphatase 0.0036 0.0133 0.0146
Echinococcus granulosus tar DNA binding protein 0.0062 0.0295 0.0324
Trypanosoma cruzi hexose transporter, putative 0.002 0.003 0.019
Trypanosoma cruzi cysteine peptidase, putative 0.0181 0.1049 0.6697
Echinococcus multilocularis General substrate transporter 0.0099 0.0533 0.0531
Loa Loa (eye worm) hypothetical protein 0.0502 0.3076 0.5311
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Trypanosoma brucei glucose transporter 1E 0.0036 0.0132 0.0844
Giardia lamblia Hypothetical protein 0.003 0.0098 0.2834
Toxoplasma gondii facilitative glucose transporter GT1 0.0116 0.0635 0.322
Echinococcus multilocularis fmrfamide receptor 0.0064 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus death domain containing protein 0.0067 0.0326 0.0358
Echinococcus granulosus lysyl tRNA synthetase 0.0026 0.0069 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0108 0.0185
Schistosoma mansoni glutamate receptor NMDA 0.0052 0.0233 0.0256
Brugia malayi GnHR receptor homolog 0.0064 0.0313 0.0538
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0013 0.0014
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0067 0.0326 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0635 0.2196
Leishmania major cathepsin L-like protease 0.0067 0.0332 0.2117
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0108 0.0185
Echinococcus multilocularis serine:threonine protein phosphatase PP1 isozyme 0.002 0.0034 0.0032
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0042 0.02
Brugia malayi Tachykinin-like peptides receptor 99D 0.0064 0.0313 0.0538
Loa Loa (eye worm) hypothetical protein 0.0067 0.0326 0.0561
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0098 0.0623
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0009 0.0012
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0019 0.0025 0.0163
Giardia lamblia Ser/Thr protein phosphatase PP1-alpha 2 catalytic subunit 0.002 0.0034 0.0802
Onchocerca volvulus 0.0064 0.0313 0.0538
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0003 0.0002
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0042 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Loa Loa (eye worm) neuropeptide F receptor 0.0064 0.0313 0.0538
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.002
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0042 0.0299
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0741
Mycobacterium leprae Probable lipase LipE 0.0035 0.0127 0.3078
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0132 0.0433
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0127 0.0415
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0215 0.0236
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0108 0.0118
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0054 0.0384
Onchocerca volvulus 0.0022 0.0042 0.0071
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0215 0.0369
Brugia malayi hypothetical protein 0.0016 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Echinococcus multilocularis sterol regulatory element binding protein 0.0083 0.0432 0.0431
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0132 0.0844
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0108 0.0185
Schistosoma mansoni hypothetical protein 0.0861 0.5339 0.5885
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0003 0.0002
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0042 0.0271
Toxoplasma gondii cell division protein CDC48AP 0.0018 0.002 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0332 0.1131
Onchocerca volvulus 0.0064 0.0313 0.0538
Onchocerca volvulus 0.0016 0.0009 0.0012
Brugia malayi jmjC domain containing protein 0.0108 0.0588 0.1014
Entamoeba histolytica hypothetical protein 0.0023 0.0054 0.0254
Trichomonas vaginalis protein phosphatase-1, putative 0.002 0.0034 0.0088
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0187 0.1084 0.3607
Loa Loa (eye worm) neuropeptide F receptor 0.0064 0.0313 0.0538
Loa Loa (eye worm) hypothetical protein 0.0033 0.0114 0.0195
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0042 0.0131
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0035 0.0129 0.0826
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0009 0.0012
Mycobacterium ulcerans glutaminase 0.0309 0.1859 1
Echinococcus multilocularis neuropeptide s receptor 0.0585 0.3599 0.3598
Echinococcus multilocularis nmda type glutamate receptor 0.0019 0.0027 0.0026
Onchocerca volvulus 0.0074 0.0371 0.0638
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0054 0.0342
Leishmania major glucose transporter, lmgt2 0.0036 0.0132 0.0844
Plasmodium vivax vivapain-2 0.0067 0.0332 0.1095
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0129 0.0128
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0035 0.0129 0.0422
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0044 0.0721
Trypanosoma brucei glucose transporter, putative 0.0036 0.0132 0.0844
Echinococcus granulosus jumonji domain containing protein 0.0046 0.0196 0.0214
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0066 0.0323 0.0354
Schistosoma mansoni rab6-interacting 0.0022 0.0047 0.0052
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0133 0.0748 0.0824
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0108 0.0185
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0066 0.0323 0.2687
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0185
Echinococcus granulosus dnaJ subfamily B 0.0861 0.5339 0.5884
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0125 0.08
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.003 0.0098 0.0623
Leishmania major cathepsin L-like protease 0.0181 0.1049 0.6697
Plasmodium falciparum phosphodiesterase delta, putative 0.003 0.0098 0.0315
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0064 0.0313 0.0345
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0035 0.0125 0.0213
Onchocerca volvulus 0.0019 0.0025 0.0042
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.0158 0.0157
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0108 0.0185
Echinococcus granulosus cathepsin l1 0.0067 0.0332 0.0364
Entamoeba histolytica cysteine proteinase, putative 0.0067 0.0332 0.2767
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0371 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Loa Loa (eye worm) hypothetical protein 0.0057 0.0263 0.0452
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0158 0.0905 0.0903
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0025 0.0059
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0066 0.0323 0.2687
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.003 0.0098 0.0096
Toxoplasma gondii protein kinase, putative 0.0326 0.1966 1
Loa Loa (eye worm) hypothetical protein 0.0171 0.0985 0.17
Schistosoma mansoni biogenic amine (5HT) receptor 0.0064 0.0313 0.0345
Brugia malayi MH2 domain containing protein 0.0116 0.0639 0.1102
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Brugia malayi hypothetical protein 0.0017 0.0013 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0025 0.0163
Brugia malayi Cathepsin L-like precursor 0.0022 0.0047 0.0078
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0023 0.005 0.0083
Echinococcus granulosus transitional endoplasmic reticulum atpase 0.003 0.0096 0.0104
Entamoeba histolytica transitional endoplasmic reticulum ATPase, putative 0.0029 0.0086 0.055
Echinococcus granulosus alpha 1A adrenergic receptor 0.0064 0.0313 0.0343
Loa Loa (eye worm) sugar transporter 0.0116 0.0635 0.1095
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0042 0.0299
Leishmania major glucose transporter, lmgt3 0.0036 0.0132 0.0844
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0069 0.0076
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Plasmodium falciparum acyl-CoA synthetase 0.0055 0.0253 0.0834
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0019 0.0036
Loa Loa (eye worm) uncoordinated protein 58 0.0019 0.0025 0.0042
Brugia malayi PHD-finger family protein 0.0033 0.0114 0.0195
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.013 0.0728 0.1255
Mycobacterium tuberculosis Putative conserved ATPase 0.0018 0.002 0.0127
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0332 0.1131
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.002 0.0035 0.0224
Loa Loa (eye worm) hypothetical protein 0.0734 0.4539 0.7838
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0003 0.002
Onchocerca volvulus 0.0171 0.0985 0.17
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.003 0.0098 0.0106
Leishmania major cathepsin L-like protease 0.0067 0.0332 0.2117
Schistosoma mansoni hypothetical protein 0.0049 0.0215 0.0237
Schistosoma mansoni hypothetical protein 0.0019 0.0027 0.003
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0771 0.477 0.4769
Loa Loa (eye worm) glutaminase 0.0309 0.1859 0.3209
Onchocerca volvulus 0.0019 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0179 0.1037 0.1035
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0042 0.02
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.003 0.0098 0.0623
Echinococcus granulosus cathepsin l cysteine peptidase 0.0067 0.0332 0.0364
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0066 0.0323 0.0555
Onchocerca volvulus 0.0067 0.0332 0.057
Brugia malayi PHD-finger family protein 0.0028 0.0081 0.0137
Leishmania major lysyl-tRNA synthetase, putative 0.0026 0.0069 0.0439
Brugia malayi Cathepsin L-like precursor 0.0067 0.0332 0.057
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0042 0.0183
Brugia malayi Dopamine receptor 0.0064 0.0313 0.0538
Echinococcus multilocularis Niemann Pick C1 protein 0.0194 0.1132 0.113
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0066 0.0323 0.1628
Schistosoma mansoni calcium-activated potassium channel 0.0299 0.1795 0.1978
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0019 0.0025 0.0042
Trypanosoma brucei glucose transporter, putative 0.0036 0.0132 0.0844
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0062 0.0295 0.0323
Schistosoma mansoni glutamate receptor NMDA 0.0062 0.0295 0.0325
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0019 0.0025 0.0042
Echinococcus multilocularis RUN 0.0022 0.0047 0.0045
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Plasmodium vivax SET domain protein, putative 0.006 0.0286 0.0944
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0025 0.0059
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0019 0.0025 0.0042
Brugia malayi Dopamine receptor protein 2 0.0064 0.0313 0.0538
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0019 0.0025 0.0163
Onchocerca volvulus 0.0083 0.043 0.0741
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0066 0.0323 0.206
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0639 0.1102
Onchocerca volvulus 0.0022 0.0047 0.0079
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0164 0.094 0.1035
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0019 0.0025 0.0024
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.004 0.0161 0.1029
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.0883 0.1522
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0185
Echinococcus granulosus sex peptide receptor 0.0064 0.0313 0.0343
Echinococcus multilocularis twik family of potassium channels 0.0019 0.0025 0.0024
Echinococcus granulosus 7tm_1 domain containing protein 0.0064 0.0313 0.0343
Loa Loa (eye worm) hypothetical protein 0.0083 0.0432 0.0744
Trichomonas vaginalis glutaminase, putative 0.0309 0.1859 0.6482
Loa Loa (eye worm) hypothetical protein 0.0067 0.0332 0.057
Plasmodium vivax CDK-related protein kinase 6, putative 0.049 0.3001 1
Mycobacterium ulcerans hypothetical protein 0.0035 0.0127 0.0641
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0323 0.11
Onchocerca volvulus 0.0016 0.0009 0.0012
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Schistosoma mansoni cpg binding protein 0.0066 0.0321 0.0354
Loa Loa (eye worm) hypothetical protein 0.0055 0.0253 0.0435
Schistosoma mansoni inositol monophosphatase 0.0036 0.0133 0.0146
Echinococcus granulosus hypothetical protein 0.0064 0.0313 0.0343
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0026 0.0069 0.1419
Echinococcus multilocularis solute carrier family 22 0.0016 0.0009 0.0007
Leishmania major glucose transporter/membrane transporter D2, putative 0.0036 0.0132 0.0844
Schistosoma mansoni calcium-activated potassium channel 0.0019 0.0025 0.0028
Brugia malayi valosin containing protein 0.0018 0.0017 0.0028
Echinococcus granulosus tm gpcr rhodopsin 0.0064 0.0313 0.0343
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0035 0.0129 0.0422
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0295 0.0507
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Loa Loa (eye worm) hypothetical protein 0.0087 0.0456 0.0786
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0125 0.0409
Trypanosoma brucei glucose transporter, putative 0.0036 0.0132 0.0844
Schistosoma mansoni hypothetical protein 0.0082 0.0425 0.0468
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0066 0.0323 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0125 0.0138
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0042 0.0183
Trypanosoma brucei glucose transporter, putative 0.0036 0.0132 0.0844
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0623
Onchocerca volvulus Putative transporter 0.0016 0.0009 0.0012
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0125 0.0138
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0025 0.0028
Onchocerca volvulus 0.0067 0.0332 0.057
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0019 0.0027 0.0026
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0066 0.0323 0.206
Echinococcus granulosus single minded 2 0.0051 0.0228 0.0249
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Schistosoma mansoni hypothetical protein 0.0067 0.0326 0.036
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0108 0.0107
Entamoeba histolytica cysteine proteinase, putative 0.0067 0.0332 0.2767
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0019 0.0025 0.0042
Echinococcus multilocularis potassium channel subfamily K 0.0019 0.0025 0.0024
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0066 0.0323 0.206
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0064 0.0313 0.0343
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0066 0.0323 0.2687
Trypanosoma cruzi serine/threonine protein phosphatase catalytic subunit, putative 0.002 0.0034 0.0216
Echinococcus multilocularis neuropeptide receptor A26 0.0585 0.3599 0.3598
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.0635 0.0699
Onchocerca volvulus 0.0022 0.0047 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.0965 0.3352
Schistosoma mansoni neuropeptide f receptor 76f 0.0064 0.0313 0.0345
Loa Loa (eye worm) hypothetical protein 0.0022 0.0047 0.0078
Echinococcus multilocularis G protein coupled receptor 139 0.0064 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0125 0.0902
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0185
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0042 0.0183
Loa Loa (eye worm) hypothetical protein 0.003 0.0098 0.0166
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Plasmodium falciparum proline--tRNA ligase 0.004 0.0161 0.0527
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0038 0.0036
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0035 0.0125 0.0213
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Onchocerca volvulus 0.0032 0.0108 0.0185
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.015 0.0851 0.1468
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Loa Loa (eye worm) PHD-finger family protein 0.0033 0.0114 0.0195
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.003 0.0098 0.0312
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0114 0.0566
Schistosoma mansoni amine GPCR 0.0064 0.0313 0.0345
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0108 0.0185
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0035 0.0125 0.08
Schistosoma mansoni hypothetical protein 0.008 0.0413 0.0455
Toxoplasma gondii cell division protein CDC48CY 0.003 0.0096 0.0473
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0019 0.0027 0.0028
Trypanosoma brucei calcium-activated potassium channel, putative 0.0019 0.0025 0.0163
Schistosoma mansoni protein kinase 0.0035 0.0129 0.0143
Schistosoma mansoni amine GPCR 0.0064 0.0313 0.0345
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0295 0.0325
Brugia malayi AKH receptor 0.0064 0.0313 0.0538
Echinococcus multilocularis g protein coupled receptor 0.0064 0.0313 0.0312
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0043 0.0179 0.1141
Onchocerca volvulus 0.0016 0.0009 0.0012
Loa Loa (eye worm) fibroinase 0.0067 0.0332 0.057
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0066 0.0323 0.0356
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0043 0.0179 0.0307
Plasmodium falciparum potassium channel 0.0019 0.0025 0.0075
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0192 0.0211
Echinococcus multilocularis small conductance calcium activated potassium 0.0502 0.3076 0.3075
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.002 0.0034 0.0088
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0185
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0067 0.0332 0.1095
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.003 0.0098 0.0623
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0064 0.0313 0.0345
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0025 0.0028
Schistosoma mansoni glutamate receptor kainate 0.0052 0.0233 0.0256
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0054 0.0168
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0043 0.0179 0.1141
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0018 0.0019 0.0121
Loa Loa (eye worm) hypothetical protein 0.003 0.0098 0.0166
Trypanosoma cruzi hexose transporter 0.0036 0.0132 0.0844
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0025 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0042 0.0071
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0133 0.0672
Echinococcus multilocularis rhodopsin orphan GPCR 0.0064 0.0313 0.0312
Schistosoma mansoni hypothetical protein 0.008 0.0413 0.0455
Echinococcus multilocularis netrin receptor unc 5 0.0067 0.0326 0.0325
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Trichomonas vaginalis bsu-protein phosphatase, putative 0.002 0.0034 0.0088
Plasmodium vivax phosphodiesterase gamma, putative 0.003 0.0098 0.0315
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0064 0.0313 0.0343
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0069 0.0326
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0038 0.0063
Loa Loa (eye worm) hypothetical protein 0.0022 0.0042 0.0071
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0066 0.0323 0.0354
Toxoplasma gondii histone lysine methyltransferase SET1 0.0119 0.0657 0.3331
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.043 0.0474
Onchocerca volvulus 0.0022 0.0042 0.0071
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus multilocularis solute carrier family 22 0.0016 0.0009 0.0007
Schistosoma mansoni biogenic amine receptor 0.0064 0.0313 0.0345
Brugia malayi Bromodomain containing protein 0.0037 0.0141 0.0242
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0215 0.0236
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0019 0.0025 0.0042
Trichomonas vaginalis spermatogenesis associated factor, putative 0.003 0.0096 0.0306
Mycobacterium ulcerans ion transport protein 0.0019 0.0025 0.0091
Plasmodium vivax acyl-CoA synthetase, putative 0.0055 0.0253 0.0834
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus somatostatin receptor 0.0064 0.0313 0.0343
Echinococcus granulosus tachykinin peptides receptor 99D 0.0064 0.0313 0.0343
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0067 0.0328 0.0361
Chlamydia trachomatis lysine--tRNA ligase 0.0026 0.0069 0.1643
Schistosoma mansoni ankyrin 23/unc44 0.0067 0.0326 0.036
Echinococcus multilocularis orexin receptor type 2 0.0064 0.0313 0.0312
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.0035 0.0129 0.0939
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0003 0.0002
Onchocerca volvulus 0.0016 0.0009 0.0012
Echinococcus granulosus peptide allatostatin:somatostatin 0.0064 0.0313 0.0343
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0064 0.0313 0.0538
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.0729 0.0803
Echinococcus multilocularis neuropeptides capa receptor 0.0064 0.0313 0.0312
Onchocerca volvulus 0.0064 0.0313 0.0538
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.002 0.0033 0.021
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0108 0.0185
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0046 0.0194 0.0332
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0116 0.0635 0.0634
Brugia malayi nuclear receptor NHR-88 0.0032 0.0108 0.0185
Echinococcus multilocularis lysyl tRNA synthetase 0.0026 0.0069 0.0067
Echinococcus granulosus RUN 0.0022 0.0047 0.005
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0371 0.0638
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0108 0.0185
Schistosoma mansoni zinc finger protein 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Echinococcus multilocularis neuropeptide receptor 0.0064 0.0313 0.0312
Schistosoma mansoni hypothetical protein 0.0151 0.0858 0.0946
Echinococcus multilocularis potassium channel subfamily K 8 0.0019 0.0025 0.0024
Onchocerca volvulus 0.0035 0.0127 0.0217
Loa Loa (eye worm) hypothetical protein 0.0055 0.0253 0.0435
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0108 0.0185
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0185
Schistosoma mansoni hypothetical protein 0.0049 0.0215 0.0237
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.0047 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Schistosoma mansoni glucose transport protein 0.0116 0.0635 0.07
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0108 0.0118
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0064 0.0313 0.0312
Leishmania major cathepsin L-like protease 0.0067 0.0332 0.2117
Loa Loa (eye worm) hypothetical protein 0.0173 0.0995 0.1717
Brugia malayi Uncoordinated protein 44 0.0067 0.0326 0.0561
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0003 0.0002
Onchocerca volvulus 0.0067 0.0332 0.057
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0019 0.0027 0.0026
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0187 0.1084 0.5508
Schistosoma mansoni hypothetical protein 0.0041 0.0163 0.018
Onchocerca volvulus 0.0067 0.0332 0.057
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0019 0.0025 0.0026
Plasmodium falciparum mitogen-activated protein kinase 2 0.0187 0.1084 0.3607
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0127 0.0414
Toxoplasma gondii lysine-tRNA ligase 0.0026 0.0069 0.0335
Echinococcus granulosus neuropeptide receptor A26 0.0585 0.3599 0.3966
Trypanosoma cruzi glucose transporter, putative 0.0016 0.0009 0.0055
Trypanosoma brucei sugar transporter, putative 0.0016 0.0009 0.0055
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0133 0.0435
Brugia malayi Cathepsin L-like precursor 0.0045 0.0191 0.0327
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0108 0.0107
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0038 0.004
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0001 0.0002
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus granulosus General substrate transporter 0.0099 0.0533 0.0586
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0066 0.0323 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0019 0.0025 0.0042
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0018 0.0023 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0332 0.1131
Brugia malayi PAS domain containing protein 0.0069 0.034 0.0586
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Echinococcus granulosus alkaline phosphatase 0.0158 0.0905 0.0996
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0064 0.0313 0.0345
Plasmodium falciparum lysine--tRNA ligase 0.0026 0.0069 0.0219
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0286 0.0315
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0042 0.0183
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0019 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.002 0.0034 0.0036
Schistosoma mansoni alpha-1 adrenergic receptor 0.0064 0.0313 0.0345
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0108 0.0118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0108 0.0185
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0185
Loa Loa (eye worm) hypothetical protein 0.0122 0.0679 0.117
Plasmodium falciparum phd finger protein, putative 0.0033 0.0114 0.0371
Echinococcus granulosus neuropeptide FF receptor 2 0.0064 0.0313 0.0343
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0295 0.0294
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0323 0.206
Plasmodium vivax hexose transporter 0.0116 0.0635 0.2109
Echinococcus granulosus neuropeptide receptor 0.0064 0.0313 0.0343
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0015 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0064 0.0313 0.0343
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.002 0.0033 0.0036
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0064 0.0313 0.0345
Onchocerca volvulus 0.0022 0.0042 0.0071
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0066 0.0323 0.0356
Toxoplasma gondii ABC1 family protein 0.0035 0.0127 0.0632
Plasmodium falciparum cysteine proteinase falcipain 3 0.0067 0.0332 0.1095
Loa Loa (eye worm) hypothetical protein 0.0932 0.579 1
Onchocerca volvulus 0.0016 0.0009 0.0012
Giardia lamblia hypothetical protein 0.003 0.0098 0.2834
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0042 0.0183
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0064 0.0313 0.0343
Schistosoma mansoni neuropeptide receptor 0.0064 0.0313 0.0345
Echinococcus granulosus neuropeptide Y receptor 0.0064 0.0313 0.0343
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0133 0.0661
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0125 0.0214
Schistosoma mansoni cell division control protein 48 aaa family protein 0.003 0.0096 0.0106
Loa Loa (eye worm) hypothetical protein 0.0045 0.0191 0.0327
Brugia malayi Hint module family protein 0.0056 0.0261 0.0449
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0025 0.0163
Echinococcus granulosus peregrin 0.0035 0.0129 0.014
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0215 0.0369
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.0047 0.0078
Brugia malayi hypothetical protein 0.0019 0.0025 0.0042
Echinococcus granulosus biogenic amine 5HT receptor 0.0064 0.0313 0.0343
Brugia malayi Glutamate receptor 1 precursor 0.0139 0.0783 0.135
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Onchocerca volvulus Cathepsin L homolog 0.0067 0.0332 0.057
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0108 0.0118
Echinococcus granulosus allatostatin A receptor 0.0064 0.0313 0.0343
Echinococcus multilocularis neuropeptides capa receptor 0.0064 0.0313 0.0312
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0098 0.0312
Plasmodium vivax potassium channel, putative 0.0019 0.0025 0.0075
Schistosoma mansoni netrin receptor unc5 0.0067 0.0326 0.036
Plasmodium vivax calcium-dependent protein kinase, putative 0.0035 0.0129 0.0422
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0035 0.0129 0.0644
Loa Loa (eye worm) hypothetical protein 0.0037 0.0142 0.0242
Plasmodium falciparum calcium-dependent protein kinase 3 0.0035 0.0129 0.0422
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0102 0.055 0.0948
Onchocerca volvulus 0.0064 0.0313 0.0538
Brugia malayi Cathepsin L-like precursor 0.0067 0.0332 0.057
Onchocerca volvulus Neuropeptide F receptor homolog 0.0064 0.0313 0.0538
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0019 0.0025 0.0042
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0133 0.0145
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0108 0.0119
Loa Loa (eye worm) hypothetical protein 0.0035 0.0125 0.0213
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0098 0.0623
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Schistosoma mansoni survival motor neuron protein 0.015 0.0851 0.0938
Loa Loa (eye worm) melatonin receptor type 1A 0.0064 0.0313 0.0538
Loa Loa (eye worm) hypothetical protein 0.0106 0.0574 0.0989
Brugia malayi G-protein coupled receptor 0.0064 0.0313 0.0538
Entamoeba histolytica protein kinase, putative 0.0035 0.0129 0.0939
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0001 0.0002
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0066 0.0073
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0125 0.0902
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0064 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0432 0.1483
Plasmodium vivax vivapain-1 0.0035 0.0125 0.0407
Echinococcus granulosus serine:threonine protein phosphatase PP1 beta 0.002 0.0034 0.0036
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0064 0.0313 0.0312
Echinococcus granulosus biogenic amine 5HT receptor 0.0064 0.0313 0.0343
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0173 0.0995 0.1717
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0108 0.0119
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0019 0.0025 0.017
Loa Loa (eye worm) hypothetical protein 0.0087 0.0456 0.0786
Echinococcus multilocularis neuropeptide receptor 0.0064 0.0313 0.0312
Mycobacterium ulcerans putative regulatory protein 0.0051 0.0228 0.1183
Brugia malayi RNA binding protein 0.0062 0.0295 0.0507
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.003
Entamoeba histolytica hypothetical protein 0.0041 0.0163 0.1244
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0295 0.0325
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0185
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0295 0.0507
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0108 0.0185
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0056 0.0261 0.0449
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0323 0.11
Brugia malayi beta-lactamase 0.0035 0.0127 0.0217
Echinococcus multilocularis serotonin receptor 0.0064 0.0313 0.0312
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0129 0.0128
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0054 0.0342
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0108 0.0588 0.0647
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0042 0.0183
Echinococcus granulosus twik family of potassium channels 0.0019 0.0025 0.0026
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0116 0.0635 0.0634
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0042 0.0668
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0019 0.0036
Leishmania major hypothetical protein, conserved 0.0019 0.0025 0.0163
Brugia malayi sulfakinin receptor protein 0.0064 0.0313 0.0538
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0018 0.0019 0.0036
Schistosoma mansoni cpg binding protein 0.0066 0.0321 0.0354
Echinococcus granulosus nuclear factor of activated T cells 5 0.0651 0.4015 0.4424
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0132 0.0844
Echinococcus granulosus potassium channel subfamily K 8 0.0019 0.0025 0.0026
Mycobacterium ulcerans ATPase 0.0018 0.002 0.006
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0042 0.0183
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0035 0.0125 0.3012
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0129 0.0141
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0064 0.0313 0.0345
Echinococcus granulosus g-protein coupled receptor 0.0064 0.0313 0.0343
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0185
Brugia malayi hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0043 0.0179 0.0196
Echinococcus granulosus potassium channel subfamily K 0.0019 0.0025 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0108 0.0185
Loa Loa (eye worm) hypothetical protein 0.0049 0.0215 0.0369
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0019 0.0025 0.0042
Plasmodium falciparum calcium-dependent protein kinase 2 0.0035 0.0129 0.0422
Plasmodium falciparum serine/threonine protein phosphatase PP1 0.002 0.0034 0.0102
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0074 0.0371 0.1956
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0108 0.0588 0.0587
Schistosoma mansoni growth hormone secretagogue receptor 0.0064 0.0313 0.0345
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0014 0.0013
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0651 0.4015 0.4014
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.003 0.0098 0.0481
Schistosoma mansoni cpg binding protein 0.006 0.0288 0.0317
Echinococcus multilocularis rhodopsin orphan GPCR 0.0064 0.0313 0.0312
Schistosoma mansoni alkaline phosphatase 0.0158 0.0905 0.0997
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0263 0.1566 0.7961
Onchocerca volvulus 0.006 0.0288 0.0494
Trypanosoma brucei cAMP-specific phosphodiesterase 0.003 0.0098 0.0623
Echinococcus multilocularis aryl hydrocarbon receptor 0.0149 0.0844 0.0843
Echinococcus multilocularis rhodopsin orphan GPCR 0.0064 0.0313 0.0312
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0083 0.0091
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0127 0.0633
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0019 0.0025 0.0042
Echinococcus multilocularis transfer RNA-Lys 0.0051 0.0228 0.0226
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0108 0.0119
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0023 0.005 0.0356
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0042 0.0271
Loa Loa (eye worm) hypothetical protein 0.0055 0.0253 0.0435
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0114 0.0371
Echinococcus granulosus glutamate receptor 2 0.0149 0.0845 0.093
Echinococcus granulosus G protein coupled receptor 139 0.0064 0.0313 0.0343
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0066 0.0071
Brugia malayi Serotonin receptor 0.0064 0.0313 0.0538
Onchocerca volvulus 0.006 0.0286 0.0492
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0286 0.0285
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0108 0.0118
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0194 0.1132 1
Schistosoma mansoni hypothetical protein 0.0106 0.0574 0.0632
Echinococcus granulosus glutamate receptor 4 0.0087 0.0456 0.0501
Loa Loa (eye worm) hypothetical protein 0.0028 0.0084 0.0142
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0286 0.0315
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0108 0.0119
Brugia malayi Hint module family protein 0.0056 0.0261 0.0449
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0035 0.0129 0.0221
Leishmania major Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog 0.0029 0.0086 0.0551
Echinococcus multilocularis rhodopsin orphan GPCR 0.0064 0.0313 0.0312
Trypanosoma cruzi ion transport protein, putative 0.0019 0.0025 0.0163
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0035 0.0125 0.0123
Brugia malayi Pre-SET motif family protein 0.006 0.0286 0.0492
Onchocerca volvulus 0.0067 0.0332 0.057
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.002 0.0034 0.0032
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0064 0.0313 0.0538
Onchocerca volvulus 0.0016 0.0009 0.0012
Leishmania major cathepsin L-like protease 0.0181 0.1049 0.6697
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0064 0.0313 0.0312
Schistosoma mansoni hypothetical protein 0.0116 0.0635 0.07
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0067 0.0326 0.0358
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0064 0.0313 0.0343
Brugia malayi aryl hydrocarbon receptor AHR-1 0.013 0.0728 0.1255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0191 0.0639
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0108 0.0185
Echinococcus granulosus dro:myosuppressin receptor 0.0064 0.0313 0.0343
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0042 0.0299
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Loa Loa (eye worm) ctsf protein 0.0067 0.0332 0.057
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0132 0.0844
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0129 0.0143
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.0253 0.1322
Trypanosoma cruzi cruzipain precursor, putative 0.0181 0.1049 0.6697
Loa Loa (eye worm) hypothetical protein 0.0087 0.0456 0.0786
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0054 0.0243
Schistosoma mansoni protein phosphatase-1 0.002 0.0034 0.0037
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0064 0.0313 0.0345
Echinococcus multilocularis cathepsin L cysteine protease 0.0067 0.0332 0.033
Trypanosoma brucei Valosin-containing protein 0.0029 0.0086 0.0551
Trypanosoma cruzi cysteine peptidase, putative 0.0181 0.1049 0.6697
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus multilocularis calcium dependent protein kinase 0.0033 0.0116 0.0114
Schistosoma mansoni adenoreceptor 0.0064 0.0313 0.0345
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0064 0.0313 0.0343
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0033 0.0054
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.002 0.0035 0.0224
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1049 0.6697
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0025 0.0059
Brugia malayi beta-lactamase family protein 0.0035 0.0127 0.0217
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0412 0.2505 0.4325
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0035 0.0129 0.0221
Brugia malayi Cathepsin L-like precursor 0.0067 0.0332 0.057
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.003 0.0098 0.0623
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0069 0.0326
Plasmodium falciparum potassium channel 0.0019 0.0025 0.0075
Echinococcus multilocularis g-protein coupled receptor 0.0064 0.0313 0.0312
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0192 0.021
Toxoplasma gondii cathepsin CPL 0.0067 0.0332 0.1673
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0025 0.0059
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0129 0.0128
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0018 0.0023 0.0021
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0064 0.0313 0.0312
Echinococcus multilocularis survival motor neuron protein 1 0.0734 0.4539 0.4538
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.003 0.0098 0.0108
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0108 0.0119
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.003 0.0098 0.0108
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0127 0.0139
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0371 0.1956
Mycobacterium tuberculosis Conserved protein 0.0035 0.0127 0.0943
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0064 0.0313 0.0312
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0019 0.0036
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0042 0.0299
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.043 0.0741
Echinococcus multilocularis G-protein coupled receptor, putative 0.0064 0.0313 0.0312
Schistosoma mansoni jumonji domain containing protein 0.0086 0.0448 0.0494
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0217
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0171 0.0986 0.1702
Leishmania major protein kinase, putative 0.002 0.0033 0.021
Leishmania major hypothetical protein, conserved 0.0035 0.0127 0.0812
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0332 0.1131
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0108 0.0107
Onchocerca volvulus Netrin receptor homolog 0.0067 0.0326 0.0561
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0067 0.0332 0.1095
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0067 0.0332 0.1131
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Schistosoma mansoni glutamate receptor kainate 0.0052 0.0233 0.0256
Echinococcus multilocularis g protein coupled receptor 0.0064 0.0313 0.0312
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0108 0.0185
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0133 0.0848
Schistosoma mansoni methyl-cpg binding protein mbd 0.0318 0.1917 0.2112
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0132 0.0844
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0012
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0019 0.0025 0.0024
Echinococcus granulosus aryl hydrocarbon receptor 0.0149 0.0844 0.0929
Echinococcus multilocularis Ankyrin 0.0067 0.0328 0.0326
Onchocerca volvulus 0.0052 0.0231 0.0397
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0108 0.0119
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0064 0.0313 0.0345
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0003 0.0003
Brugia malayi neuropeptide F receptor 0.0064 0.0313 0.0538
Echinococcus granulosus potassium channel subfamily K 8 0.0019 0.0025 0.0026
Brugia malayi Serotonin receptor 0.0064 0.0313 0.0538
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus granulosus rhodopsin orphan GPCR 0.0064 0.0313 0.0343
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0332 0.1131
Loa Loa (eye worm) hypothetical protein 0.0055 0.0253 0.0435
Schistosoma mansoni protein phosphatase-1 0.002 0.0034 0.0037
Plasmodium vivax proline--tRNA ligase, putative 0.004 0.0161 0.0527
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0108 0.0107
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0312
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Echinococcus multilocularis calcium activated potassium channel variant 0.0019 0.0025 0.0024
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.003 0.0098 0.0096
Echinococcus granulosus GPCR family 2 0.0049 0.0215 0.0236
Entamoeba histolytica cysteine proteinase 1, putative 0.0035 0.0125 0.0902
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Plasmodium vivax vivapain-2 0.0067 0.0332 0.1095
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0133 0.0848
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.003 0.0098 0.0096
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0035 0.0129 0.0644
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0064 0.0313 0.0345
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0217
Echinococcus multilocularis solute carrier family 22 0.0016 0.0009 0.0007
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0019 0.0025 0.0042
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0035 0.0129 0.0221
Echinococcus granulosus glutamate receptor 2 0.013 0.0724 0.0796
Echinococcus granulosus solute carrier family 22 0.0016 0.0009 0.0008
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0042 0.0183
Loa Loa (eye worm) glutaminase 2 0.0309 0.1859 0.3209
Schistosoma mansoni neuropeptide F-like receptor 0.0064 0.0313 0.0345
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0047 0.005
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0042 0.0183
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0125 0.0214
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0042 0.0271
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0025 0.0028
Loa Loa (eye worm) glutamate receptor 2 0.0052 0.0233 0.04
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.003 0.0098 0.0106
Trichomonas vaginalis esterase, putative 0.0035 0.0127 0.0415
Leishmania major cysteine peptidase A (CPA) 0.0067 0.0332 0.2117
Brugia malayi Cathepsin L-like precursor 0.0067 0.0332 0.057
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0013 0.002
Brugia malayi TAR-binding protein 0.0062 0.0295 0.0507
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0083 0.0432 0.0744
Trypanosoma brucei glucose transporter, putative 0.0036 0.0132 0.0844
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0064 0.0313 0.0312
Trypanosoma cruzi cysteine proteinase, putative 0.0035 0.0125 0.08
Echinococcus multilocularis expressed conserved protein 0.0182 0.1057 0.1056
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0042 0.0183
Onchocerca volvulus 0.0064 0.0313 0.0538
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0108 0.0119
Onchocerca volvulus 0.0045 0.0191 0.0327
Mycobacterium ulcerans beta-lactamase 0.0035 0.0127 0.0641
Brugia malayi Death domain containing protein 0.0067 0.0326 0.0561
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.002 0.0035 0.0058
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0025 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0108 0.0185
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.003 0.0098 0.0108
Trypanosoma cruzi cysteine protease, putative 0.0035 0.0125 0.08
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0022 0.0047 0.0079
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0192 0.0329
Echinococcus granulosus orexin receptor type 2 0.0064 0.0313 0.0343
Loa Loa (eye worm) vesicle-fusing ATPase 0.0018 0.0017 0.0028
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.003 0.0098 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0109 0.2564
Loa Loa (eye worm) hypothetical protein 0.0022 0.0047 0.0078
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Schistosoma mansoni hypothetical protein 0.0019 0.0025 0.0028
Brugia malayi neuropeptide F receptor 0.0064 0.0313 0.0538
Onchocerca volvulus 0.0019 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0217
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0064 0.0313 0.0538
Onchocerca volvulus Cathepsin L homolog 0.0067 0.0332 0.057
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0371 0.1956
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0064 0.0313 0.0345
Schistosoma mansoni neuropeptide receptor 0.0064 0.0313 0.0345
Onchocerca volvulus 0.0016 0.0009 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0125 0.0902
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0042 0.0071
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.0574 0.0989
Schistosoma mansoni lozenge 0.0117 0.0644 0.071
Trypanosoma cruzi sugar transporter, putative 0.0016 0.0009 0.0055
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0064 0.0313 0.0538
Trichomonas vaginalis protein phosphatase, caeel, putative 0.002 0.0034 0.0088
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0263 0.1566 1
Brugia malayi Cathepsin L-like precursor 0.0067 0.0332 0.057
Onchocerca volvulus 0.0064 0.0313 0.0538
Loa Loa (eye worm) hypothetical protein 0.0056 0.0261 0.0449
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0042 0.0271
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0062 0.0295 0.0293
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.003 0.0098 0.0108
Schistosoma mansoni twik family of potassium channels-related 0.0019 0.0025 0.0028
Echinococcus granulosus protein phosphatase 1, catalytic subunit, beta isozyme 0.002 0.0034 0.0036
Plasmodium falciparum protein kinase 7 0.0326 0.1966 0.6549
Loa Loa (eye worm) hypothetical protein 0.0155 0.0883 0.1522
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Echinococcus granulosus cathepsin L cysteine proteinase 0.0067 0.0332 0.0364
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0371 1
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0132 0.0433
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0042 0.0271
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0064 0.0313 0.0345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0332 0.1131
Brugia malayi hypothetical protein 0.0064 0.0313 0.0538
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0042 0.0299
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0623
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0234 0.1756
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0018 0.0019 0.0036
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus multilocularis Niemann Pick C1 protein 0.0277 0.1657 0.1656
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0042 0.0045
Plasmodium falciparum cGMP-specific phosphodiesterase 0.003 0.0098 0.0315
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0054 0.0168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0108 0.0185
Loa Loa (eye worm) hypothetical protein 0.0064 0.0313 0.0538
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0127 0.3078
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0323 0.206
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0066 0.0323 1
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0066 0.0323 0.0321
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Onchocerca volvulus 0.0064 0.0313 0.0538
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0066 0.0323 0.0321
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0179 0.1037 0.1143
Toxoplasma gondii ion channel protein 0.0019 0.0025 0.0114
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.003 0.0098 0.0623
Echinococcus granulosus cysteine protease 0.0035 0.0125 0.0136
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0019 0.0027 0.0028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0234 0.1756
Brugia malayi Sugar transporter family protein 0.0016 0.0009 0.0012
Echinococcus multilocularis cysteine protease 0.0067 0.0332 0.033
Brugia malayi cathepsin L-like precursor 0.0045 0.0191 0.0327
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.0883 0.1522
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0109 0.0806
Mycobacterium tuberculosis Conserved protein 0.0035 0.0127 0.0943
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0014 0.0014
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0013 0.0011
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0035 0.0125 0.0138
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0055 0.0253 0.771
Entamoeba histolytica cysteine protease, putative 0.0035 0.0125 0.0902
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0133 0.0848
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Schistosoma mansoni neuropeptide receptor 0.0064 0.0313 0.0345
Trypanosoma cruzi major cysteine proteinase, putative 0.0126 0.0702 0.4482
Echinococcus multilocularis serotonin receptor 0.0064 0.0313 0.0312
Loa Loa (eye worm) runx1 0.0117 0.0644 0.111
Echinococcus granulosus cathepsin l1 0.0045 0.0191 0.0209
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0042
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0215 0.0369
Echinococcus multilocularis Protein lozenge 0.0117 0.0644 0.0643
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0042 0.0299
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0064 0.0313 0.0345
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0016 0.0009 0.0018
Echinococcus granulosus cathepsin L 0.0035 0.0125 0.0136
Plasmodium falciparum protein kinase 6 0.049 0.3001 1
Brugia malayi hypothetical protein 0.0064 0.0313 0.0538
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0158 0.0905 0.0996
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0064 0.0313 0.0538
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0067 0.0332 0.033
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0064 0.0313 0.0538
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.003 0.0098 0.0312
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0106 0.0577 0.0576
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.003 0.0098 0.0315
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0074 0.0371 0.0638
Onchocerca volvulus 0.0016 0.0009 0.0012
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0035 0.0125 0.0407
Brugia malayi CHE-14 protein 0.0083 0.0432 0.0744
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0127 0.0415
Leishmania major protein kinase, putative 0.002 0.0033 0.021
Leishmania major hypothetical protein, conserved 0.003 0.0098 0.0623
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0127 0.0415
Echinococcus granulosus calcium activated potassium channel variant 0.0019 0.0025 0.0026
Leishmania major myo-inositol/proton symporter (MIT) 0.0016 0.0009 0.0055
Schistosoma mansoni nuclear receptor 0.0015 0.0001 0.0002
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0019 0.0025 0.0042

Activities

Activity type Activity value Assay description Source Reference
EC50 (ADMET) < 10 uM Cytotoxicity against human BJ cells after 72 hrs by alamar blue assay ChEMBL. 19769357
EC50 (ADMET) < 10 uM Cytotoxicity against human Raji cells after 72 hrs by alamar blue assay ChEMBL. 19769357
EC50 (ADMET) < 10 uM Cytotoxicity against human HepG2 cells after 72 hrs by alamar blue assay ChEMBL. 19769357
EC50 (ADMET) < 10 uM Cytotoxicity against human HEK293 cells after 72 hrs by alamar blue assay ChEMBL. 19769357
EC50 (functional) = 30 uM Antimalarial activity as reduced parasitaemia after 72 hrs against chloroquine-sensitive Plasmodium falciparum 3D7 infected human O+ erythrocytes by DNA stain with pepstatin ChEMBL. 19447616
EC50 (functional) > 30 uM Antimalarial activity as reduced parasitaemia after 72 hrs against chloroquine-sensitive Plasmodium falciparum 3D7 infected human O+ erythrocytes by DNA stain without pepstatin ChEMBL. 19447616
EC50 (functional) = 42 uM Antitrypanosomal activity against Trypanosoma brucei after 48 hrs ChEMBL. 19769357
IC50 (binding) = 1.8 uM Inhibition of human liver cathepsin L ChEMBL. 19769357
IC50 (binding) = 9 uM Inhibition of Trypanosoma brucei rhodesiense rhodesain ChEMBL. 19769357
IC50 (binding) > 50 uM Inhibition of human liver cathepsin B ChEMBL. 19769357

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 19769357

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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