Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0052 | 0.0291 | 0.0291 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0241 | 0.0241 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.019 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0241 | 0.0241 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0163 | 0.0318 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0016 | 0.0016 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0077 | 0.3328 |
Leishmania major | trypanothione reductase | 0.0038 | 0.0176 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.002 | 0.0042 | 0.0042 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0594 | 0.0594 |
Schistosoma mansoni | cpg binding protein | 0.0062 | 0.0364 | 0.0364 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0038 | 0.0176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0115 | 0.0115 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0132 | 0.0132 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0132 | 0.0132 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0288 | 0.2125 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0594 | 0.0594 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0162 | 0.1144 | 0.1144 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1593 | 0.1593 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0024 | 0.0069 | 0.1469 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0132 | 0.0132 |
Brugia malayi | MH2 domain containing protein | 0.0121 | 0.0825 | 0.0825 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0132 | 0.0132 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0172 | 0.0771 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0194 | 0.0387 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0028 | 0.0028 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0052 | 0.0291 | 0.0291 |
Onchocerca volvulus | 0.022 | 0.1593 | 0.4166 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0061 | 0.0075 |
Onchocerca volvulus | 0.022 | 0.1593 | 0.4166 | |
Brugia malayi | glutaminase DH11.1 | 0.0272 | 0.1999 | 0.1999 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0545 | 0.0545 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0172 | 0.0338 |
Loa Loa (eye worm) | carboxylesterase | 0.022 | 0.1593 | 0.1593 |
Loa Loa (eye worm) | carboxylesterase | 0.1302 | 1 | 1 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0085 | 0.0545 | 0.0545 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0241 | 0.0241 |
Echinococcus granulosus | BC026374 protein S09 family | 0.022 | 0.1593 | 0.1593 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0061 | 0.0061 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0101 | 0.0668 | 0.0668 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0438 | 0.0438 |
Brugia malayi | Thioredoxin reductase | 0.0038 | 0.0176 | 0.0176 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.0969 | 0.0969 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0028 | 0.009 |
Toxoplasma gondii | thioredoxin reductase | 0.0038 | 0.0176 | 0.2014 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.0115 | 0.0115 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0172 | 0.0739 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0594 | 0.0594 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0061 | 0.2241 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0163 | 0.0163 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.019 | 0.019 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0103 | 0.0183 |
Echinococcus multilocularis | peregrin | 0.003 | 0.0115 | 0.0115 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0077 | 0.3821 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0046 | 0.0241 | 0.0241 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.022 | 0.1593 | 0.1593 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0098 | 0.0643 | 0.0643 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0061 | 0.0213 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0121 | 0.0825 | 0.0825 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0172 | 0.0771 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0052 | 0.0291 | 0.0291 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0591 | 0.4471 | 1 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.003 | 0.0116 | 0.0116 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0085 | 0.0545 | 0.0545 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0163 | 0.0304 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0172 | 0.0338 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0091 | 0.0091 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0038 | 0.0176 | 0.079 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0101 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1593 | 0.1593 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0132 | 0.0132 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0028 | 0.0739 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0591 | 0.4471 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.004 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0016 | 0.0016 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0127 | 0.0866 | 0.0866 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0172 | 0.0771 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0091 | 0.0091 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.022 | 0.1593 | 0.1593 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1593 | 0.1593 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0024 | 0.0069 | 0.0285 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0061 | 0.0075 |
Schistosoma mansoni | acetylcholinesterase | 0.022 | 0.1593 | 0.1593 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0594 | 0.0594 |
Schistosoma mansoni | jumonji domain containing protein | 0.0078 | 0.0487 | 0.0487 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0218 | 0.044 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0162 | 0.1144 | 0.1144 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0085 | 0.0545 | 0.0545 |
Brugia malayi | jmjC domain containing protein | 0.0039 | 0.019 | 0.019 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0163 | 0.0318 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0172 | 0.0172 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0077 | 0.067 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0241 | 0.0241 |
Echinococcus granulosus | dnaJ subfamily B | 0.0834 | 0.6364 | 0.6364 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0061 | 0.0247 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0288 | 0.2125 | 1 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0438 | 0.0438 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0172 | 0.4313 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0172 | 0.0771 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.022 | 0.1593 | 0.1593 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0024 | 0.0069 | 1 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.0302 | |
Brugia malayi | CXXC zinc finger family protein | 0.0059 | 0.0338 | 0.0338 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0132 | 0.0132 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.4471 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0438 | 0.0438 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0024 | 0.0069 | 0.0093 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0132 | 0.0132 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0091 | 0.0091 |
Mycobacterium leprae | conserved hypothetical protein | 0.0024 | 0.0069 | 0.0039 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0038 | 0.018 | 0.018 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0206 | 0.0206 |
Mycobacterium tuberculosis | Probable reductase | 0.0086 | 0.0551 | 0.2563 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0096 | 0.0626 | 0.2915 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0024 | 0.0069 | 0.3322 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0172 | 0.0771 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0077 | 0.3328 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.0969 | 0.0969 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0028 | 0.0028 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0172 | 0.0338 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0077 | 0.0124 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0172 | 0.196 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1302 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1302 | 1 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0028 | 0.0014 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0064 | 0.0378 | 0.0378 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0052 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0091 | 0.0091 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0077 | 0.3328 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.022 | 0.1593 | 0.7486 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.0115 | 0.0196 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0038 | 0.0176 | 0.4422 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0172 | 0.0172 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0172 | 0.9733 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0024 | 0.0069 | 0.0252 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0172 | 0.9733 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0163 | 0.0318 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.022 | 0.1593 | 0.7486 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.022 | 0.1593 | 0.1593 |
Onchocerca volvulus | 0.0094 | 0.0613 | 0.15 | |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0172 | 0.0739 |
Brugia malayi | Heterochromatin protein 1 | 0.0071 | 0.0438 | 0.0438 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0064 | 0.0378 | 0.0378 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0591 | 0.4471 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0172 | 0.0537 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0027 | 0.009 | 0.009 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0194 | 0.0387 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0061 | 0.0061 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0077 | 0.3821 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0594 | 0.0594 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0086 | 0.0551 | 0.2563 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0163 | 0.9124 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0172 | 0.0172 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0039 | 0.019 | 0.019 |
Trypanosoma brucei | trypanothione reductase | 0.0038 | 0.0176 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0194 | 0.0194 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.006 | 0.035 | 0.035 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0115 | 0.1186 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0103 | 0.0183 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0025 | 0.0077 | 0.0124 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0019 | 0.0029 | 0.0017 |
Plasmodium falciparum | glutathione reductase | 0.0038 | 0.0176 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0077 | 0.0124 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0046 | 0.0241 | 0.0241 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0061 | 0.0061 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0163 | 0.0318 |
Plasmodium vivax | SET domain protein, putative | 0.0064 | 0.0378 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.022 | 0.1593 | 0.1593 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0115 | 0.6195 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0017 | 0.0014 | 0.0014 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0024 | 0.0069 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.022 | 0.1593 | 0.1593 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0172 | 0.9733 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0163 | 0.0163 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0163 | 0.1837 |
Schistosoma mansoni | glutaminase | 0.0272 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.0594 | 0.0594 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0086 | 0.0551 | 0.2563 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0061 | 0.0247 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0438 | 0.0438 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0172 | 0.9733 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0017 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.0172 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0288 | 0.2125 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0028 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1593 | 0.1593 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.042 | 0.042 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0046 | 0.0241 | 0.0241 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.022 | 0.1593 | 0.7486 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.4471 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.022 | 0.1593 | 0.1593 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0281 | 0.0281 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1593 | 0.1593 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.4471 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0028 | 0.0327 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0052 | 0.0291 | 0.0291 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0077 | 0.0077 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0172 | 0.0771 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0016 | 0.0016 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0064 | 0.0378 | 0.0378 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0172 | 0.0771 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0064 | 0.0378 | 0.0378 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.042 | 0.042 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0162 | 0.1144 | 0.1144 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0085 | 0.0545 | 0.0545 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0024 | 0.0069 | 0.2789 |
Brugia malayi | Carboxylesterase family protein | 0.022 | 0.1593 | 0.1593 |
Onchocerca volvulus | 0.0059 | 0.0338 | 0.0754 | |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0241 | 0.0241 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0172 | 0.0338 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0172 | 0.0739 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0218 | 0.044 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0132 | 0.0132 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0064 | 0.0378 | 0.4756 |
Mycobacterium ulcerans | glutaminase | 0.0272 | 0.1999 | 0.9406 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0163 | 0.9124 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0029 | 0.0017 |
Loa Loa (eye worm) | glutathione reductase | 0.0038 | 0.0176 | 0.0176 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0163 | 0.0318 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0163 | 0.9124 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1593 | 0.1593 |
Schistosoma mansoni | cpg binding protein | 0.0059 | 0.0338 | 0.0338 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0086 | 0.0551 | 0.2563 |
Brugia malayi | Carboxylesterase family protein | 0.1302 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.0172 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0438 | 0.0935 |
Schistosoma mansoni | lamin | 0.0027 | 0.0091 | 0.0091 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0061 | 0.0213 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0164 | 0.0164 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0438 | 0.0935 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0098 | 0.0643 | 0.0643 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0059 | 0.0338 | 0.0338 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0172 | 0.0771 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0071 | 0.0438 | 0.0438 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.022 | 0.1593 | 0.1593 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0163 | 0.0318 |
Brugia malayi | glutathione reductase | 0.0038 | 0.0176 | 0.0176 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1188 | 0.1188 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.4471 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0062 | 0.0364 | 0.0364 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0172 | 0.0338 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.4471 | 1 |
Onchocerca volvulus | 0.0027 | 0.0091 | 0.0081 | |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0163 | 0.0304 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0172 | 0.0172 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.0302 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0077 | 0.0124 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.022 | 0.1593 | 0.1593 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0378 | 0.0378 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0163 | 0.0163 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0162 | 0.1144 | 0.1144 |
Echinococcus multilocularis | geminin | 0.0168 | 0.1188 | 0.1188 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0096 | 0.0626 | 0.2736 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0163 | 0.0318 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0668 | 0.0668 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0024 | 0.0069 | 0.2789 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0121 | 0.0825 | 0.0825 |
Brugia malayi | jmjC domain containing protein | 0.0098 | 0.0643 | 0.0643 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0024 | 0.0069 | 0.0562 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0069 | 0.0093 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0077 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0016 | 0.0016 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0163 | 0.0318 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.022 | 0.1593 | 0.1593 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0185 | 0.1323 | 0.1323 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.022 | 0.1593 | 0.1593 |
Plasmodium falciparum | thioredoxin reductase | 0.0038 | 0.0176 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0086 | 0.0551 | 0.2375 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0046 | 0.0241 | 0.0241 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1302 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0009 | 0.0009 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0046 | 0.0241 | 0.049 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0052 | 0.0291 | 0.0291 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0115 | 0.1186 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0132 | 0.0132 |
Echinococcus multilocularis | neuroligin | 0.022 | 0.1593 | 0.1593 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0025 | 0.0077 | 0.0124 |
Onchocerca volvulus | Alhambra homolog | 0.003 | 0.0115 | 0.0147 |
Brugia malayi | Carboxylesterase family protein | 0.022 | 0.1593 | 0.1593 |
Loa Loa (eye worm) | MBCTL1 | 0.0052 | 0.0291 | 0.0291 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0061 | 0.0213 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.022 | 0.1593 | 0.7477 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0172 | 0.0771 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0061 | 0.0213 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0113 | 0.0763 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.0594 | 0.0594 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0077 | 0.0124 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0028 | 0.0028 |
Schistosoma mansoni | hypothetical protein | 0.0284 | 0.2089 | 0.2089 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0115 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0077 | 0.0077 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0028 | 0.0028 |
Brugia malayi | Bromodomain containing protein | 0.003 | 0.0115 | 0.0115 |
Onchocerca volvulus | 0.0075 | 0.0468 | 0.1108 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0064 | 0.0378 | 0.0378 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0172 | 0.0172 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0046 | 0.0241 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0127 | 0.0127 |
Brugia malayi | SET domain containing protein | 0.0015 | 0.0002 | 0.0002 |
Brugia malayi | Pre-SET motif family protein | 0.0436 | 0.3271 | 0.3271 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.0115 | 0.274 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0438 | 0.0438 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0163 | 0.0163 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0115 | 0.0115 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0091 | 0.0091 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0061 | 0.0061 |
Echinococcus multilocularis | cpg binding protein | 0.0062 | 0.0364 | 0.0364 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0086 | 0.0551 | 0.2563 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0061 | 0.0213 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0028 | 0.0028 |
Onchocerca volvulus | 0.0046 | 0.0241 | 0.049 | |
Schistosoma mansoni | lamin | 0.0027 | 0.0091 | 0.0091 |
Onchocerca volvulus | 0.0085 | 0.0545 | 0.1316 | |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.002 | 0.0042 | 0.0042 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.4471 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0096 | 0.0626 | 0.2915 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0172 | 0.0172 |
Onchocerca volvulus | 0.022 | 0.1593 | 0.4166 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0087 | 0.0087 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.004 | 0.0194 | 0.0361 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0218 | 0.0425 |
Echinococcus multilocularis | acetylcholinesterase | 0.1302 | 1 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0172 | 0.0172 |
Echinococcus granulosus | acetylcholinesterase | 0.1302 | 1 | 1 |
Onchocerca volvulus | 0.022 | 0.1593 | 0.4166 | |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0162 | 0.1144 | 0.1144 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0172 | 0.0739 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.002 | 0.0042 | 0.0042 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0046 | 0.0241 | 0.0241 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0172 | 0.0537 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.042 | 0.042 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0017 | 0.0014 | 0.0014 |
Echinococcus granulosus | acetylcholinesterase | 0.1302 | 1 | 1 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0024 | 0.0069 | 0.0562 |
Brugia malayi | Carboxylesterase family protein | 0.022 | 0.1593 | 0.1593 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0172 | 0.0172 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0061 | 0.2241 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0061 | 0.0213 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0101 | 0.0668 | 0.0668 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0061 | 0.0061 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0016 | 0.0034 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0077 | 0.3328 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0077 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.0172 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0091 | 0.0091 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0115 | 0.0115 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0024 | 0.0069 | 0.0252 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0172 | 0.0771 |
Loa Loa (eye worm) | glutaminase | 0.0272 | 0.1999 | 0.1999 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.4471 | 1 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.0302 | |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0075 | 0.0468 | 0.0468 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0591 | 0.4471 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0062 | 0.0364 | 0.0364 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0436 | 0.3271 | 0.3271 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0061 | 0.0075 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0061 | 0.0213 |
Onchocerca volvulus | 0.022 | 0.1593 | 0.4166 | |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0172 | 0.0338 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0064 | 0.0378 | 0.0378 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0096 | 0.0626 | 0.2915 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0172 | 0.0739 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.022 | 0.1593 | 0.353 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0039 | 0.019 | 0.019 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0028 | 0.0014 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0061 | 0.0213 |
Trichomonas vaginalis | glutaminase, putative | 0.0272 | 0.1999 | 0.4444 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0594 | 0.0594 |
Onchocerca volvulus | 0.0027 | 0.0091 | 0.0081 | |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1593 | 0.1593 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1302 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0063 | 0.0063 |
Echinococcus granulosus | lamin | 0.0027 | 0.0091 | 0.0091 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0016 | 0.0016 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0091 | 0.0091 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0163 | 0.0318 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0834 | 0.6364 | 0.6364 |
Loa Loa (eye worm) | hypothetical protein | 0.1302 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0132 | 0.0132 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0061 | 0.2241 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.4471 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0086 | 0.0551 | 0.2563 |
Echinococcus granulosus | neuroligin | 0.022 | 0.1593 | 0.1593 |
Echinococcus granulosus | geminin | 0.0168 | 0.1188 | 0.1188 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.0172 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0063 | 0.0063 |
Echinococcus granulosus | carboxylesterase 5A | 0.1302 | 1 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0496 | 0.3737 | 0.8351 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1188 | 0.1188 |
Echinococcus multilocularis | acetylcholinesterase | 0.1302 | 1 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0185 | 0.1323 | 0.1323 |
Schistosoma mansoni | gliotactin | 0.022 | 0.1593 | 0.1593 |
Brugia malayi | hypothetical protein | 0.022 | 0.1593 | 0.1593 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.0172 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0594 | 0.0594 |
Onchocerca volvulus | 0.0496 | 0.3737 | 1 | |
Loa Loa (eye worm) | glutaminase 2 | 0.0272 | 0.1999 | 0.1999 |
Echinococcus granulosus | peregrin | 0.003 | 0.0115 | 0.0115 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0172 | 0.0172 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0132 | 0.0132 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0206 | 0.0206 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.022 | 0.1593 | 0.1593 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0163 | 0.9124 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0115 | 0.0115 |
Schistosoma mansoni | hypothetical protein | 0.0834 | 0.6364 | 0.6364 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0038 | 0.0176 | 0.0176 |
Plasmodium vivax | glutathione reductase, putative | 0.0038 | 0.0176 | 0.4422 |
Brugia malayi | Pre-SET motif family protein | 0.0064 | 0.0378 | 0.0378 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0238 | 0.1729 | 0.8129 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.0362 | 0.0362 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.022 | 0.1593 | 0.353 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0038 | 0.018 | 0.018 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0163 | 0.0163 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.0115 | 0.0115 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0091 | 0.0091 |
Onchocerca volvulus | 0.0031 | 0.0127 | 0.0179 | |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0077 | 0.169 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 80.6 mg kg-1 | Anticonvulsant activity in ip dosed albino Carworth Farms No.1 mouse assessed as protection against maximal electroshock-induced seizure after 0.25 hrs | ChEMBL. | 21862182 |
ED50 (functional) | > 200 mg kg-1 | Anticonvulsant activity in ip dosed albino Carworth Farms No.1 mouse assessed as protection against subcutaneous metrazol-induced seizure after 0.25 hrs | ChEMBL. | 21862182 |
TD50 (ADMET) | = 178.1 mg kg-1 | Neurotoxicity in ip dosed albino Carworth Farms No.1 mouse assessed as motor impairment after 0.25 hrs by rotarod test | ChEMBL. | 21862182 |
Time (functional) | = 0.25 hr | Anticonvulsant activity in ip dosed albino Carworth Farms No.1 mouse assessed as time needs to show peak effect for protection against maximal electroshock-induced seizure | ChEMBL. | 21862182 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.