Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0016 | 0.0009 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0045 | 0.0012 | 0.0101 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.1944 | 0.1967 | 0.169 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.5569 | 0.57 | 1 |
Echinococcus granulosus | choline O acetyltransferase | 0.1206 | 0.1208 | 0.2119 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.5569 | 0.57 | 1 |
Onchocerca volvulus | 0.1206 | 0.1208 | 0.5 | |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.1944 | 0.1967 | 0.1962 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.5569 | 0.57 | 1 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0049 | 0.0016 | 0.0028 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.1944 | 0.1967 | 0.1965 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.1944 | 0.1967 | 0.3451 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.1206 | 0.1208 | 0.1202 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.5569 | 0.57 | 1 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.5569 | 0.57 | 1 |
Brugia malayi | Choline O-acetyltransferase | 0.1206 | 0.1208 | 0.1206 |
Echinococcus multilocularis | choline O acetyltransferase | 0.1206 | 0.1208 | 0.2119 |
Loa Loa (eye worm) | hypothetical protein | 0.1206 | 0.1208 | 0.1202 |
Schistosoma mansoni | choline o-acyltransferase | 0.1206 | 0.1208 | 1 |
Onchocerca volvulus | 0.1206 | 0.1208 | 0.5 | |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.1944 | 0.1967 | 1 |
Brugia malayi | Choline O-acetyltransferase | 0.1206 | 0.1208 | 0.1206 |
Onchocerca volvulus | 0.1206 | 0.1208 | 0.5 | |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.1206 | 0.1208 | 0.1202 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.1206 | 0.1208 | 0.1206 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.1944 | 0.1967 | 0.169 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0049 | 0.0016 | 0.0028 |
Onchocerca volvulus | 0.1206 | 0.1208 | 0.5 | |
Schistosoma mansoni | choline o-acyltransferase | 0.1206 | 0.1208 | 1 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.004 | 0.0007 | 0.0004 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.1944 | 0.1967 | 0.3451 |
Loa Loa (eye worm) | hypothetical protein | 0.9746 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.