Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | acetylcholinesterase | 0.027 | 0.8467 | 1 |
Brugia malayi | Telomerase reverse transcriptase | 0.0229 | 0.7107 | 0.8394 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0086 | 0.2302 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0046 | 0.094 | 0.0671 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0398 | 0.0374 |
Echinococcus multilocularis | acetylcholinesterase | 0.027 | 0.8467 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.027 | 0.8467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0398 | 0.0091 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0046 | 0.094 | 0.0713 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0046 | 0.094 | 0.0671 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.094 | 0.0671 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0324 | 0.0383 |
Giardia lamblia | Telomerase catalytic subunit | 0.0086 | 0.2302 | 0.5 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0086 | 0.2302 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0046 | 0.094 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.027 | 0.8467 | 1 |
Onchocerca volvulus | 0.0046 | 0.094 | 0.0564 | |
Loa Loa (eye worm) | carboxylesterase | 0.027 | 0.8467 | 1 |
Onchocerca volvulus | 0.0046 | 0.094 | 0.0564 | |
Brugia malayi | Pre-SET motif family protein | 0.0205 | 0.6302 | 0.7443 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.094 | 0.0756 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0046 | 0.094 | 0.0671 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.094 | 0.111 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0046 | 0.094 | 0.0713 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0046 | 0.094 | 0.5 |
Trichomonas vaginalis | set domain proteins, putative | 0.0234 | 0.7254 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0398 | 0.047 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.094 | 0.0671 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.094 | 0.0756 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0205 | 0.6302 | 0.7342 |
Echinococcus multilocularis | carboxylesterase 5A | 0.027 | 0.8467 | 1 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0086 | 0.2302 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.8467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.094 | 0.0756 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0086 | 0.2302 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0046 | 0.094 | 0.0671 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0086 | 0.2302 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.027 | 0.8467 | 1 |
Brugia malayi | hypothetical protein | 0.0046 | 0.094 | 0.111 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0046 | 0.094 | 0.0671 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.094 | 0.111 |
Loa Loa (eye worm) | carboxylesterase | 0.0046 | 0.094 | 0.0756 |
Echinococcus granulosus | acetylcholinesterase | 0.027 | 0.8467 | 1 |
Onchocerca volvulus | 0.0234 | 0.7254 | 0.7141 | |
Onchocerca volvulus | 0.0046 | 0.094 | 0.0564 | |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.094 | 0.111 |
Echinococcus multilocularis | neuroligin | 0.0046 | 0.094 | 0.0671 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0046 | 0.094 | 0.5 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0086 | 0.2302 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.094 | 0.0756 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0046 | 0.094 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.027 | 0.8467 | 1 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0086 | 0.2302 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0046 | 0.094 | 0.0671 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.094 | 0.0756 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0046 | 0.094 | 0.0713 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.094 | 0.111 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.027 | 0.8467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.094 | 0.0756 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.094 | 0.0671 |
Echinococcus granulosus | neuroligin | 0.0046 | 0.094 | 0.0713 |
Loa Loa (eye worm) | carboxylesterase | 0.0046 | 0.094 | 0.0756 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0398 | 0.0045 |
Onchocerca volvulus | 0.0046 | 0.094 | 0.0564 | |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0398 | 0.0374 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.094 | 0.0756 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.027 | 0.8467 | 1 |
Schistosoma mansoni | gliotactin | 0.0046 | 0.094 | 0.0671 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.8467 | 1 |
Onchocerca volvulus | 0.0046 | 0.094 | 0.0564 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.