Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0214 | 0.1635 | 0.1635 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0077 | 0.0509 | 0.063 |
Schistosoma mansoni | polycystin 1-related | 0.0022 | 0.0049 | 0.0049 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0214 | 0.1635 | 0.1921 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0993 | 0.8072 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0022 | 0.0049 | 0.0302 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0035 | 0.0048 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0247 | 0.1217 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0018 | 0.0013 | 0.0082 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0063 | 0.0063 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0198 | 0.1005 |
Echinococcus granulosus | thymidine kinase | 0.0518 | 0.415 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0148 | 0.0148 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0035 | 0.0171 |
Schistosoma mansoni | hypothetical protein | 0.0523 | 0.4187 | 0.4187 |
Echinococcus multilocularis | thymidine kinase | 0.0518 | 0.415 | 0.569 |
Brugia malayi | isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0066 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0116 | 0.0829 | 0.4197 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.0502 | 0.0622 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0105 | 0.0733 | 0.3719 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.004 | 0.0198 | 0.1214 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0035 | 0.0147 |
Trypanosoma brucei | thymidine kinase | 0.0993 | 0.8072 | 1 |
Brugia malayi | hypothetical protein | 0.0262 | 0.2034 | 1 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0105 | 0.0739 | 0.3765 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0899 | 0.7293 | 1 |
Loa Loa (eye worm) | phosphofructokinase | 0.0105 | 0.0739 | 0.3619 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0107 | 0.0751 | 0.3679 |
Mycobacterium ulcerans | lipase LipD | 0.004 | 0.0198 | 0.1214 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0214 | 0.1635 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0077 | 0.0502 | 0.0622 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0255 | 0.1975 | 1 |
Mycobacterium ulcerans | thymidylate kinase | 0.0214 | 0.1635 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0027 | 0.0092 | 0.0222 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.004 | 0.0198 | 0.0478 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.003 | 0.0117 | 0.0574 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.004 | 0.0198 | 0.1005 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.031 | 0.031 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0128 | 0.0929 | 0.2238 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0028 | 0.0104 | 0.0129 |
Echinococcus multilocularis | transfer RNA-Ile | 0.0518 | 0.415 | 0.569 |
Toxoplasma gondii | ABC1 family protein | 0.004 | 0.0198 | 0.1214 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.026 | 0.1277 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.026 | 0.0356 |
Brugia malayi | thymidylate kinase | 0.0214 | 0.1635 | 0.8037 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0058 | 0.035 | 0.2141 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0058 | 0.035 | 0.17 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0018 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.0739 | 0.0916 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.026 | 0.0626 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0028 | 0.0104 | 0.0636 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.0148 | 0.0728 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0022 | 0.0049 | 0.0068 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0104 | 0.0129 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0013 | 0.0017 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0035 | 0.0171 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0035 | 0.0171 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0035 | 0.0171 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0069 | 0.0436 | 0.2207 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0035 | 0.0147 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0022 | 0.0049 | 0.0302 |
Echinococcus granulosus | lamin dm0 | 0.0056 | 0.0332 | 0.0799 |
Giardia lamblia | Deoxynucleoside kinase | 0.0384 | 0.3038 | 0.3764 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0077 | 0.0502 | 0.05 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.004 | 0.0198 | 0.0953 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0751 | 0.3679 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0022 | 0.0049 | 0.0068 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.0301 | 0.1842 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0323 | 0.1568 |
Entamoeba histolytica | thymidine kinase, putative | 0.0993 | 0.8072 | 1 |
Schistosoma mansoni | loxhd1 | 0.0022 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | beta-lactamase | 0.004 | 0.0198 | 0.0953 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0993 | 0.8072 | 1 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0105 | 0.0739 | 0.0916 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0105 | 0.0733 | 0.3709 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0198 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0035 | 0.0147 |
Brugia malayi | intermediate filament protein | 0.0056 | 0.0332 | 0.1631 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0148 | 0.0357 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0198 | 0.0246 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.0066 | 0.0411 | 0.2351 |
Trypanosoma brucei | RNA helicase, putative | 0.0523 | 0.4187 | 0.5187 |
Brugia malayi | Isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0066 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0035 | 0.0035 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0035 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0198 | 0.0953 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.0739 | 0.0739 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0035 | 0.0171 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.0739 | 0.0797 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0035 | 0.0171 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0018 | 0.0013 | 0.0068 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0049 | 0.0242 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0198 | 0.0953 |
Onchocerca volvulus | 0.0022 | 0.0049 | 0.0091 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0092 | 0.0429 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.004 | 0.0198 | 0.1005 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0035 | 0.0084 |
Schistosoma mansoni | hypothetical protein | 0.0352 | 0.2777 | 0.2777 |
Schistosoma mansoni | thymidylate kinase | 0.0214 | 0.1635 | 0.1635 |
Onchocerca volvulus | 0.004 | 0.0198 | 0.1023 | |
Echinococcus granulosus | geminin | 0.0352 | 0.2777 | 0.6693 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0058 | 0.035 | 0.1772 |
Schistosoma mansoni | phosphoglucomutase | 0.0066 | 0.0411 | 0.0411 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0035 | 0.0048 |
Brugia malayi | follicle stimulating hormone receptor | 0.0226 | 0.1736 | 0.8536 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0116 | 0.0829 | 0.4197 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0035 | 0.0171 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.0247 | 0.1514 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0061 | 0.0374 | 0.0513 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0077 | 0.0502 | 0.0622 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.0198 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0035 | 0.0147 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.0739 | 0.0916 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0013 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0301 | 0.148 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0035 | 0.0171 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0035 | 0.0048 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0084 | 0.0562 | 0.0696 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0035 | 0.0171 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0021 | 0.004 | 0.0195 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0035 | 0.0171 |
Brugia malayi | beta-lactamase | 0.004 | 0.0198 | 0.0976 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.0739 | 0.0916 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0116 | 0.0829 | 0.4197 |
Wolbachia endosymbiont of Brugia malayi | thymidylate kinase | 0.0214 | 0.1635 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.026 | 0.026 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0077 | 0.0509 | 0.063 |
Schistosoma mansoni | intermediate filament proteins | 0.0056 | 0.0332 | 0.0332 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0993 | 0.8072 | 1 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0018 | 0.0019 | 0.0116 |
Echinococcus granulosus | intermediate filament protein | 0.0056 | 0.0332 | 0.0799 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0058 | 0.035 | 0.0433 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0104 | 0.0129 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.003 | 0.0117 | 0.055 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.0739 | 0.3635 |
Echinococcus multilocularis | bloom syndrome protein | 0.0021 | 0.004 | 0.0054 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0104 | 0.0129 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.0739 | 0.0739 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0035 | 0.0147 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0058 | 0.035 | 0.048 |
Echinococcus multilocularis | thymidylate kinase | 0.0214 | 0.1635 | 0.2241 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0198 | 0.0198 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0035 | 0.0171 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.0739 | 0.0916 |
Echinococcus granulosus | bloom syndrome protein | 0.0021 | 0.004 | 0.0096 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0077 | 0.0509 | 0.063 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0035 | 0.0035 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0214 | 0.1635 | 0.2025 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0027 | 0.0092 | 0.0126 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0022 | 0.0049 | 0.0119 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0022 | 0.0049 | 0.0068 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0035 | 0.0171 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0028 | 0.0104 | 0.0636 |
Echinococcus multilocularis | ribonuclease H1 | 0.0066 | 0.0411 | 0.0563 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0058 | 0.035 | 0.2141 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0198 | 0.0953 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0056 | 0.0332 | 0.1631 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0028 | 0.0104 | 0.0636 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0018 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0226 | 0.1736 | 0.8533 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0066 | 0.0411 | 0.0509 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0028 | 0.0104 | 0.0636 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0028 | 0.0104 | 0.0636 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0148 | 0.0148 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0063 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0035 | 0.0147 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0058 | 0.035 | 0.0433 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0035 | 0.0171 |
Brugia malayi | Inositol-1 | 0.0077 | 0.0502 | 0.2469 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0028 | 0.0104 | 0.0636 |
Onchocerca volvulus | 0.0053 | 0.031 | 0.1723 | |
Echinococcus granulosus | ribonuclease H1 | 0.0066 | 0.0411 | 0.099 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0018 | 0.0013 | 0.0017 |
Plasmodium falciparum | thymidylate kinase | 0.0214 | 0.1635 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0082 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.004 | 0.0198 | 0.1005 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0035 | 0.0147 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.026 | 0.1256 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0148 | 0.0357 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0214 | 0.1635 | 0.2025 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0198 | 0.0118 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0058 | 0.035 | 0.0433 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.0502 | 0.0622 |
Giardia lamblia | Thymidine kinase | 0.0993 | 0.8072 | 1 |
Echinococcus multilocularis | RUN | 0.0022 | 0.0049 | 0.0068 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0198 | 0.0118 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0032 |
Brugia malayi | RNase H family protein | 0.0066 | 0.0411 | 0.202 |
Schistosoma mansoni | rab6-interacting | 0.0022 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0035 | 0.0147 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.004 | 0.0198 | 0.1005 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0066 | 0.0411 | 0.0509 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0058 | 0.035 | 0.0433 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0084 | 0.0562 | 0.0696 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.0198 | 0.0976 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0066 | 0.0411 | 0.2514 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0198 | 0.1005 |
Chlamydia trachomatis | thymidylate kinase | 0.0214 | 0.1635 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.0247 | 0.1514 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0041 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.0739 | 0.3619 |
Echinococcus granulosus | thymidine kinase | 0.0518 | 0.415 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0058 | 0.035 | 0.0433 |
Trypanosoma brucei | hypothetical protein, conserved | 0.004 | 0.0198 | 0.0246 |
Echinococcus multilocularis | thymidine kinase | 0.0518 | 0.415 | 0.569 |
Brugia malayi | Doublecortin family protein | 0.0022 | 0.0049 | 0.0242 |
Leishmania major | hypothetical protein, conserved | 0.004 | 0.0198 | 0.0246 |
Onchocerca volvulus | 0.004 | 0.0198 | 0.1023 | |
Loa Loa (eye worm) | RecQ helicase | 0.0021 | 0.004 | 0.017 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.004 | 0.0198 | 0.0272 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0018 | 0.0013 | 0.0082 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.0739 | 0.3619 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0061 | 0.0374 | 0.0902 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0198 | 0.1005 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.0739 | 0.0916 |
Schistosoma mansoni | inositol monophosphatase | 0.0077 | 0.0502 | 0.0502 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0105 | 0.0733 | 0.3709 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0148 | 0.0148 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0105 | 0.0739 | 0.1014 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0035 | 0.0035 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0105 | 0.0739 | 0.1781 |
Echinococcus multilocularis | GPCR, family 2 | 0.0034 | 0.0148 | 0.0203 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0035 | 0.0171 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.0198 | 0.0198 |
Leishmania major | thymidylate kinase-like protein | 0.0214 | 0.1635 | 0.2025 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0058 | 0.035 | 0.0309 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0104 | 0.0129 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0018 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0035 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0198 | 0.0953 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0214 | 0.1635 | 0.2025 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.004 | 0.0198 | 0.1005 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0198 | 0.0246 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0214 | 0.1635 | 1 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0077 | 0.0502 | 0.0689 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0077 | 0.0502 | 0.121 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0035 | 0.0048 |
Brugia malayi | RNase H family protein | 0.0066 | 0.0411 | 0.202 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0198 | 0.0118 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0247 | 0.1195 |
Giardia lamblia | CDC8 | 0.0214 | 0.1635 | 0.2025 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0148 | 0.1095 | 0.1501 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0035 | 0.0147 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0066 | 0.0411 | 0.2514 |
Echinococcus granulosus | lamin | 0.0056 | 0.0332 | 0.0799 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0082 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0107 | 0.0751 | 0.3694 |
Echinococcus multilocularis | lamin dm0 | 0.0056 | 0.0332 | 0.0455 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0214 | 0.1635 | 0.2025 |
Echinococcus granulosus | Thymidine kinase 2 mitochondrial | 0.0518 | 0.415 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.0739 | 0.3635 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0262 | 0.2034 | 0.4901 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0035 | 0.0147 |
Schistosoma mansoni | ap endonuclease | 0.0058 | 0.035 | 0.035 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0013 | 0.0017 |
Schistosoma mansoni | lipoxygenase | 0.0022 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0035 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0198 | 0.0953 |
Schistosoma mansoni | lipoxygenase | 0.0061 | 0.0374 | 0.0374 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.0247 | 0.1253 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0058 | 0.035 | 0.0843 |
Toxoplasma gondii | ribonuclease HI protein | 0.0066 | 0.0411 | 0.2514 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0105 | 0.0733 | 0.3709 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0472 | 0.0472 |
Schistosoma mansoni | thymidylate kinase | 0.0214 | 0.1635 | 0.1635 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0035 | 0.0084 |
Echinococcus multilocularis | lamin | 0.0056 | 0.0332 | 0.0455 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0058 | 0.035 | 0.2141 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0247 | 0.1514 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.0198 | 0.0246 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.031 | 0.031 |
Loa Loa (eye worm) | inositol-1 | 0.0077 | 0.0502 | 0.2451 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0035 | 0.0035 |
Trypanosoma brucei | unspecified product | 0.0077 | 0.0509 | 0.063 |
Loa Loa (eye worm) | doublecortin family protein | 0.0022 | 0.0049 | 0.0218 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.0198 | 0.0198 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0105 | 0.0739 | 0.3743 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0035 | 0.0171 |
Mycobacterium tuberculosis | Probable hydrolase | 0.004 | 0.0198 | 0.1005 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0022 | 0.0049 | 0.0119 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0247 | 0.1217 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0993 | 0.8072 | 1 |
Leishmania major | thymidine kinase, putative | 0.0993 | 0.8072 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0035 | 0.0171 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0058 | 0.035 | 0.2141 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0058 | 0.035 | 0.2141 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0049 | 0.0049 |
Schistosoma mansoni | rab6-interacting | 0.0022 | 0.0049 | 0.0049 |
Schistosoma mansoni | hypothetical protein | 0.0128 | 0.0929 | 0.0929 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0028 | 0.0104 | 0.0636 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.026 | 0.0356 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.004 | 0.0198 | 0.0976 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0035 | 0.0035 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0198 | 0.0246 |
Plasmodium vivax | hypothetical protein, conserved | 0.004 | 0.0198 | 0.1214 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0148 | 0.0727 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0107 | 0.0751 | 0.3694 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0128 | 0.0929 | 0.1274 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.0502 | 0.0622 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.0198 | 0.0478 |
Giardia lamblia | Ribonuclease H | 0.0066 | 0.0411 | 0.0509 |
Brugia malayi | RNase H family protein | 0.0066 | 0.0411 | 0.202 |
Schistosoma mansoni | hypothetical protein | 0.0352 | 0.2777 | 0.2777 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.004 | 0.0198 | 0.1214 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0022 | 0.0049 | 0.0119 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.0301 | 0.0373 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0035 | 0.0171 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.004 | 0.0049 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0077 | 0.0502 | 0.3072 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0077 | 0.0502 | 0.3072 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.0198 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0198 | 0.0953 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.0301 | 0.1842 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.026 | 0.026 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0148 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0301 | 0.1459 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0084 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0084 | 0.0388 |
Schistosoma mansoni | ap endonuclease | 0.0058 | 0.035 | 0.035 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0035 | 0.0171 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0035 | 0.0084 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0013 | 0.0017 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.026 | 0.0626 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0035 | 0.0048 |
Loa Loa (eye worm) | intermediate filament protein | 0.0056 | 0.0332 | 0.161 |
Onchocerca volvulus | 0.004 | 0.0198 | 0.1023 | |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.0301 | 0.1842 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0104 | 0.0129 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0063 | 0.0151 |
Echinococcus multilocularis | musashi | 0.0056 | 0.0332 | 0.0455 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0049 | 0.0242 |
Schistosoma mansoni | thyroid hormone receptor | 0.0148 | 0.1095 | 0.1095 |
Leishmania major | hypothetical protein, conserved | 0.0084 | 0.0562 | 0.0696 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0035 | 0.0147 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0035 | 0.0035 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.0739 | 0.0797 |
Onchocerca volvulus | 0.0056 | 0.0332 | 0.1855 | |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0247 | 0.1514 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0262 | 0.2034 | 0.2789 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0028 | 0.0104 | 0.0129 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0069 | 0.0436 | 0.1653 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0198 | 0.0246 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.004 | 0.0198 | 0.1005 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0049 | 0.0218 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0247 | 0.0339 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.0739 | 0.0797 |
Echinococcus granulosus | thymidylate kinase | 0.0214 | 0.1635 | 0.3939 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0148 | 0.0203 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0013 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0035 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.2034 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0035 | 0.0048 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.0301 | 0.0373 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0105 | 0.0739 | 0.4522 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0247 | 0.0596 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0049 | 0.0218 |
Toxoplasma gondii | thymidylate kinase | 0.0214 | 0.1635 | 1 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0214 | 0.1635 | 0.2025 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0035 | 0.0048 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0035 | 0.0035 |
Schistosoma mansoni | thyroid hormone receptor | 0.0148 | 0.1095 | 0.1095 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.0502 | 0.0622 |
Trypanosoma brucei | ribonuclease H1 | 0.0066 | 0.0411 | 0.0509 |
Brugia malayi | phosphofructokinase | 0.0105 | 0.0739 | 0.3635 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0073 | 0.0472 | 0.2321 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.031 | 0.1526 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.0301 | 0.0373 |
Brugia malayi | hypothetical protein | 0.004 | 0.0198 | 0.0974 |
Mycobacterium ulcerans | beta-lactamase | 0.004 | 0.0198 | 0.1214 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0016 | 0.0004 | 0.0004 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0021 | 0.004 | 0.0049 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0056 | 0.0332 | 0.161 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0035 | 0.0084 |
Schistosoma mansoni | thymidine kinase | 0.0518 | 0.415 | 0.415 |
Loa Loa (eye worm) | thymidylate kinase | 0.0214 | 0.1635 | 0.8032 |
Schistosoma mansoni | phosphoglucomutase | 0.0066 | 0.0411 | 0.0411 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.0198 | 0.0246 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0247 | 0.1195 |
Plasmodium vivax | thymidylate kinase, putative | 0.0214 | 0.1635 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0035 | 0.0048 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.0198 | 0.0976 |
Toxoplasma gondii | exonuclease III APE | 0.0058 | 0.035 | 0.2141 |
Echinococcus multilocularis | geminin | 0.0352 | 0.2777 | 0.3808 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0028 | 0.0104 | 0.0636 |
Leishmania major | ribonuclease H1, putative | 0.0066 | 0.0411 | 0.0509 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0148 | 0.0148 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0035 | 0.0084 |
Onchocerca volvulus | 0.0022 | 0.0049 | 0.0091 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0035 | 0.0084 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0247 | 0.0307 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0058 | 0.035 | 0.0433 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0332 | 0.161 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.0301 | 0.0373 |
Schistosoma mansoni | lamin | 0.0056 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.0148 | 0.0705 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0035 | 0.0147 |
Echinococcus granulosus | RUN | 0.0022 | 0.0049 | 0.0119 |
Leishmania major | trypanothione reductase | 0.0046 | 0.0247 | 0.0307 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0035 | 0.0147 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0058 | 0.035 | 0.1721 |
Schistosoma mansoni | inositol monophosphatase | 0.0077 | 0.0502 | 0.0502 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0148 | 0.0705 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0104 | 0.0129 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.0148 | 0.0728 |
Schistosoma mansoni | family A2 unassigned peptidase (A02 family) | 0.0223 | 0.1711 | 0.1711 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0105 | 0.0733 | 0.3709 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0077 | 0.0502 | 0.0622 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0018 | 0.0013 | 0.0017 |
Treponema pallidum | thymidylate kinase (tmk) | 0.0214 | 0.1635 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0035 | 0.0035 |
Echinococcus granulosus | GPCR family 2 | 0.0034 | 0.0148 | 0.0357 |
Mycobacterium tuberculosis | Probable reductase | 0.0105 | 0.0733 | 0.3709 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0028 | 0.0104 | 0.0636 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.0301 | 0.1842 |
Trichomonas vaginalis | esterase, putative | 0.004 | 0.0198 | 0.0246 |
Onchocerca volvulus | 0.0056 | 0.0332 | 0.1855 | |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0035 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0778 | 0.0778 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0035 | 0.0084 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0116 | 0.0829 | 0.439 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0214 | 0.1635 | 0.8277 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0066 | 0.0411 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0472 | 0.2302 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0214 | 0.1635 | 0.2025 |
Mycobacterium ulcerans | hypothetical protein | 0.004 | 0.0198 | 0.1214 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0993 | 0.8072 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0018 | 0.0013 | 0.0018 |
Schistosoma mansoni | lamin | 0.0056 | 0.0332 | 0.0332 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0077 | 0.0509 | 0.063 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.0739 | 0.0916 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0035 | 0.0171 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0105 | 0.0739 | 0.4522 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.0247 | 0.0307 |
Schistosoma mansoni | phosphoglucomutase | 0.0066 | 0.0411 | 0.0411 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0105 | 0.0733 | 0.3709 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0035 | 0.0147 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.0247 | 0.1514 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0028 | 0.0104 | 0.0636 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0077 | 0.0502 | 0.3072 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0198 | 0.0118 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0035 | 0.0171 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0058 | 0.035 | 0.0433 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED150 (functional) | = 1.3 mg kg-1 | Effective dose against aconitine-induced arrhythmia after intravenal administration in anesthetized rats | ChEMBL. | 3806567 |
LD50 (ADMET) | = 20 mg kg-1 | Acute toxicity determined after intravenal administration in mice | ChEMBL. | 3806567 |
LD50 (ADMET) | = 20 mg kg-1 | Acute toxicity determined after intravenal administration in mice | ChEMBL. | 3806567 |
No. of positive cases (functional) | = 8 | Tested for incidence of arrhythmias in rats after a intravenal administration of 2 mg/kg of the compound expressed as no. of positive cases out of no. of tested cases (10) | ChEMBL. | 3806567 |
Relative potency (functional) | = 9.2 | Relative potency with reference to quinidine | ChEMBL. | 3806567 |
Therapeutic index (ADMET) | = 14.9 | Therapeutic index calculated as the ratio of LD50 in mice to ED 150 in rat when administered intravenously | ChEMBL. | 3806567 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.