Detailed information for compound 1581999

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 783.144 | Formula: C46H46N4S4++
  • H donors: 0 H acceptors: 0 LogP: 14.01 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 2
  • SMILES: C1CCC[n+]2c(/C=C/C=c/3\sc4c(n3CCCCCC[n+]3c(/C=C/C=c\5/n(CC1)c1ccccc1s5)sc1c3cccc1)cccc4)sc1c2cccc1
  • InChi: 1S/C46H46N4S4/c1-2-14-32-48-36-20-6-10-24-40(36)52-44(48)28-18-30-46-50(38-22-8-12-26-42(38)54-46)34-16-4-3-15-33-49-37-21-7-11-25-41(37)53-45(49)29-17-27-43-47(31-13-1)35-19-5-9-23-39(35)51-43/h5-12,17-30H,1-4,13-16,31-34H2/q+2
  • InChiKey: IVQYZLKTERXNQH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0084 0.1541 0.5613
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0095 0.0089
Loa Loa (eye worm) hypothetical protein 0.0036 0.0462 0.0456
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0128 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0148 0.0158
Brugia malayi hypothetical protein 0.0021 0.0146 0.014
Entamoeba histolytica protein kinase, putative 0.0197 0.4025 1
Brugia malayi beta-lactamase family protein 0.0036 0.0462 0.0456
Schistosoma mansoni single-minded 0.0048 0.073 0.0684
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.057 0.0511
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.132 0.1319
Schistosoma mansoni loxhd1 0.0021 0.0128 0.0036
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0982 0.0956
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.132 0.1319
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.2058 0.2115
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0438 0.9379 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0148 0.0092
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0074 0.132 0.1315
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0462 0.1523
Schistosoma mansoni lipoxygenase 0.0124 0.2408 0.2491
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.057 0.0564
Echinococcus granulosus geminin 0.0176 0.3566 0.3739
Leishmania major DNA polymerase kappa, putative 0.0022 0.0148 0.0092
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.2415 0.2411
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0191 0.0499
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0462 0.2002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0148 0.0092
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0302 0.0224
Loa Loa (eye worm) cytochrome P450 0.0084 0.1541 0.1536
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.057 0.0564
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0074 0.132 0.132
Echinococcus granulosus dual specificity protein kinase clk2 0.0438 0.9379 1
Echinococcus granulosus dual specificity 0.0197 0.4025 0.4233
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0084 0.1541 0.5613
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0095 0.0035
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0326 0.0249
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.2948 0.2944
Brugia malayi nuclear receptor RXR 0.0019 0.0095 0.0089
Loa Loa (eye worm) cytochrome P450 family protein 0.0255 0.5327 0.5325
Echinococcus multilocularis dna polymerase eta 0.0022 0.0148 0.0058
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0084 0.1541 0.1587
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0084 0.1541 0.3206
Loa Loa (eye worm) hypothetical protein 0.003 0.0326 0.0321
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0084 0.1541 0.1587
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.2058 0.2114
Echinococcus multilocularis geminin 0.0176 0.3566 0.3739
Entamoeba histolytica hypothetical protein 0.0197 0.4025 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.057 0.0564
Onchocerca volvulus 0.0036 0.0462 0.0768
Brugia malayi nuclear hormone receptor 0.0019 0.0095 0.0089
Onchocerca volvulus 0.0028 0.0297 0.0422
Echinococcus granulosus dna polymerase kappa 0.0022 0.0148 0.0058
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0148 0.0234
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0148 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.057 0.0564
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0084 0.1541 0.3206
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.057 0.0511
Leishmania major DNA polymerase eta, putative 0.0022 0.0148 0.0092
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0191 0.0499
Schistosoma mansoni polycystin 1-related 0.0021 0.0128 0.0036
Brugia malayi beta-lactamase 0.0036 0.0462 0.0456
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0148 0.0158
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0462 0.0903
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0108 0.2058 0.2142
Loa Loa (eye worm) hypothetical protein 0.0041 0.057 0.0564
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0095 0.0089
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0148 0.0158
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.057 0.0564
Loa Loa (eye worm) hypothetical protein 0.0028 0.0297 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.057 0.0564
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.057 0.0564
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.0054
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0084 0.1541 0.5613
Loa Loa (eye worm) hypothetical protein 0.0191 0.3908 0.3905
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0074 0.132 0.135
Schistosoma mansoni nuclear hormone receptor 0.0041 0.057 0.0511
Loa Loa (eye worm) hypothetical protein 0.0021 0.0146 0.014
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0982 0.0977
Schistosoma mansoni cytochrome P450 0.0084 0.1541 0.1557
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0148 0.0058
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0326 0.025
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0084 0.1541 0.1587
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0084 0.1541 0.5613
Brugia malayi hypothetical protein 0.0019 0.0095 0.0089
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.0054
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0191 0.0499
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.057 0.0511
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0084 0.1541 0.5613
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.132 0.1407
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0084 0.1541 0.3206
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.057 0.0511
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0148 0.0158
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.2058 0.2114
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Brugia malayi cytochrome P450 0.0084 0.1541 0.1536
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0095 0.5
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Schistosoma mansoni serine/threonine protein kinase 0.0438 0.9379 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0084 0.1541 0.3206
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.057 0.0994
Trichomonas vaginalis set domain proteins, putative 0.0235 0.4873 0.5147
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.057 0.0994
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0095 0.0089
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0084 0.1541 0.5613
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0197 0.4025 0.4253
Loa Loa (eye worm) hypothetical protein 0.016 0.3224 0.322
Onchocerca volvulus 0.0235 0.4873 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0108 0.2058 0.2115
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0084 0.1541 0.5613
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.1161 0.1179
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0095 0.0035
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0084 0.1541 0.5613
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0148 0.0092
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0191 0.0186
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0084 0.1541 0.5613
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0146 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0148 0.0158
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0148 0.0142
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.057 0.0511
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0148 0.0158
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0326 0.025
Loa Loa (eye worm) hypothetical protein 0.0036 0.0462 0.0456
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0074 0.132 0.132
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0462 0.0395
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0074 0.132 0.132
Loa Loa (eye worm) CYP4Cod1 0.0137 0.2698 0.2694
Brugia malayi Protein kinase domain containing protein 0.0438 0.9379 0.9379
Schistosoma mansoni intermediate filament proteins 0.0028 0.0297 0.0217
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0148 0.0335
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.2058 0.2114
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0815 0.081
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.057 0.0564
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.057 0.0511
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0128 0.0073
Schistosoma mansoni rab6-interacting 0.0021 0.0128 0.0036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.057 0.0511
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.057 0.0564
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0191 0.0499
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0455 0.0388
Giardia lamblia Kinase, CMGC CLK 0.0438 0.9379 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0074 0.132 0.132
Echinococcus multilocularis 0.0084 0.1541 0.1557
Brugia malayi PAS domain containing protein 0.0048 0.073 0.0724
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0084 0.1541 0.3206
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0095 0.5
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0128 0.0036
Leishmania major hypothetical protein, conserved 0.0036 0.0462 0.0428
Loa Loa (eye worm) hypothetical protein 0.0021 0.0146 0.014
Schistosoma mansoni hypothetical protein 0.0176 0.3566 0.3739
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0462 0.0431
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.057 0.0564
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.2058 0.2114
Loa Loa (eye worm) hypothetical protein 0.0041 0.057 0.0564
Onchocerca volvulus 0.003 0.0326 0.0485
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0326 0.025
Loa Loa (eye worm) hypothetical protein 0.0041 0.057 0.0564
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.1161 0.1237
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0084 0.1541 0.3206
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.1161 0.1155
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0438 0.9379 1
Loa Loa (eye worm) DR-78 0.0019 0.0095 0.0089
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0146 0.0055
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.057 0.0511
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0148 0.0234
Mycobacterium ulcerans hypothetical protein 0.0036 0.0462 0.1523
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.057 0.0511
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0095 0.0121
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0148 0.0058
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0074 0.132 0.1319
Echinococcus granulosus cytochrome P450 2K1 0.0084 0.1541 0.1557
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0197 0.4025 0.4253
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0191 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0148 0.0158
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.057 0.0511
Trypanosoma brucei unspecified product 0.0022 0.0148 0.0158
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0982 0.0956
Mycobacterium tuberculosis Conserved protein 0.0036 0.0462 0.0903
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0462 0.0903
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.132 0.1319
Toxoplasma gondii cytochrome p450 superfamily protein 0.0084 0.1541 0.1557
Echinococcus multilocularis dual specificity protein kinase clk2 0.0438 0.9379 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.057 0.0564
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0084 0.1541 0.3206
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0084 0.1541 0.1643
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0148 0.0335
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0095 0.0089
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.1161 0.1155
Schistosoma mansoni DNA polymerase eta 0.0022 0.0148 0.0058
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0084 0.1541 0.3206
Schistosoma mansoni lamin 0.0028 0.0297 0.0217
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0084 0.1541 0.3206
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0128 0.0036
Trypanosoma brucei cytochrome P450, putative 0.0137 0.2698 0.2877
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0462 0.0395
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0084 0.1541 0.5613
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0146 0.014
Brugia malayi intermediate filament protein 0.0028 0.0297 0.0291
Leishmania major cytochrome p450-like protein 0.0137 0.2698 0.2829
Loa Loa (eye worm) hypothetical protein 0.0021 0.0146 0.014
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0108 0.2058 0.2142
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0533 0.0472
Loa Loa (eye worm) hypothetical protein 0.0028 0.0285 0.0279
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0438 0.9379 1
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0148 0.0158
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0438 0.9379 1
Brugia malayi Cytochrome P450 family protein 0.0255 0.5327 0.5325
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0146 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.057 0.0564
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0438 0.9379 0.9379
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0191 0.0139
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.057 0.0564
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.057 0.0564
Echinococcus granulosus FTZ F1 alpha 0.0041 0.057 0.0511
Leishmania major cytochrome p450-like protein 0.0084 0.1541 0.1587
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0095 0.0101
Loa Loa (eye worm) hypothetical protein 0.0024 0.0191 0.0186
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0084 0.1541 0.3206
Loa Loa (eye worm) hypothetical protein 0.0041 0.057 0.0564
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0084 0.1541 0.5613
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.057 0.0564
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.057 0.0511
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0084 0.1541 0.1587
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0095 0.0038
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.1161 0.1179
Echinococcus granulosus hypothetical protein 0.0433 0.9263 0.9875
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0462 0.1523
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0084 0.1541 0.5613
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Schistosoma mansoni lipoxygenase 0.0086 0.1584 0.1604
Schistosoma mansoni serine/threonine protein kinase 0.0438 0.9379 1
Echinococcus multilocularis RUN 0.0021 0.0128 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0191 0.0186
Brugia malayi nuclear receptor NHR-67 0.0019 0.0095 0.0089
Loa Loa (eye worm) hypothetical protein 0.0021 0.0146 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0148 0.0158
Loa Loa (eye worm) hypothetical protein 0.0433 0.9263 0.9262
Echinococcus multilocularis lamin 0.0028 0.0297 0.0217
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0197 0.4025 0.4021
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.1161 0.2711
Echinococcus granulosus mitogen activated protein kinase 0.0108 0.2058 0.2115
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.0982 0.0987
Loa Loa (eye worm) hypothetical protein 0.0024 0.0191 0.0186
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.2058 0.2142
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0095 0.0089
Echinococcus granulosus single minded 2 0.0035 0.0455 0.0388
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0074 0.132 0.132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0191 0.0245
Trichomonas vaginalis CMGC family protein kinase 0.0438 0.9379 1
Brugia malayi Pre-SET motif family protein 0.003 0.0326 0.0321
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.073 0.0684
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0095 0.0089
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0108 0.2058 0.2114
Echinococcus granulosus RUN 0.0021 0.0128 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.057 0.0511
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0148 0.0092
Loa Loa (eye worm) hypothetical protein 0.0191 0.3908 0.3905
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0462 0.0395
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0191 0.0245
Brugia malayi beta-lactamase family protein 0.0036 0.0462 0.0456
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0095 0.0089
Loa Loa (eye worm) cytochrome P450 family protein 0.0137 0.2698 0.2694
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.057 0.0564
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0148 0.0158
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0462 0.0492
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0148 0.0057
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.132 0.135
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0084 0.1541 0.3206
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0148 0.0135
Brugia malayi Cytochrome P450 family protein 0.0137 0.2698 0.2694
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0084 0.1541 0.3206
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.1161 0.1148
Brugia malayi ecdysone receptor 0.0019 0.0095 0.0089
Trichomonas vaginalis esterase, putative 0.0036 0.0462 0.0395
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.0982 0.2014
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0148 0.0142
Leishmania major cytochrome p450-like protein 0.0084 0.1541 0.1587
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.057 0.0994
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0108 0.2058 0.2053
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0533 0.0472
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.2415 0.2411
Loa Loa (eye worm) hypothetical protein 0.0074 0.132 0.1315
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.4723 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0095 0.0038
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0108 0.2058 0.2142
Loa Loa (eye worm) hypothetical protein 0.0036 0.0462 0.0456
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0084 0.1541 0.5613
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0191 0.0499
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0191 0.0499
Brugia malayi nuclear hormone receptor 0.0041 0.057 0.0564
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Brugia malayi Doublecortin family protein 0.0021 0.0128 0.0122
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0438 0.9379 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0191 0.0139
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.057 0.0564
Mycobacterium tuberculosis Conserved protein 0.0036 0.0462 0.0903
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0462 0.0456
Mycobacterium leprae putative cytochrome p450 0.0084 0.1541 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0095 0.0035
Brugia malayi hypothetical protein 0.016 0.3224 0.322
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.057 0.0511
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0148 0.0158
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0084 0.1541 0.3206
Schistosoma mansoni hypothetical protein 0.0021 0.0128 0.0036
Echinococcus granulosus intermediate filament protein 0.0028 0.0297 0.0217
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0074 0.132 0.3117
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.057 0.0511
Loa Loa (eye worm) beta-lactamase 0.0036 0.0462 0.0456
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0462 0.0395
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.057 0.0511
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0128 0.0036
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0095 0.0134
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.057 0.0511
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.057 0.0511
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.057 0.0564
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0297 0.0291
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0084 0.1541 0.5613
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0438 0.9379 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.057 0.0564
Entamoeba histolytica protein kinase, putative 0.0197 0.4025 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0462 0.0395
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0084 0.1541 0.3206
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0197 0.4025 0.4291
Loa Loa (eye worm) hypothetical protein 0.0036 0.0462 0.0456
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0148 0.0092
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0084 0.1541 0.3206
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0084 0.1541 0.5613
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.4025 0.4233
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0146 0.0055
Plasmodium vivax serine/threonine kinase-1, putative 0.0438 0.9379 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.057 0.0564
Mycobacterium leprae Probable lipase LipE 0.0036 0.0462 0.2002
Trypanosoma cruzi cytochrome P450, putative 0.0137 0.2698 0.2829
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.1161 0.1179
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0191 0.0186
Onchocerca volvulus 0.0036 0.0462 0.0768
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0148 0.0158
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0326 0.025
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.1161 0.1148
Echinococcus multilocularis mitogen activated protein kinase 3 0.0108 0.2058 0.2115
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0462 0.0395
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.057 0.0511
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0084 0.1541 0.3206
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0124 0.2408 0.2491
Brugia malayi nuclear receptor RXR 0.0021 0.0146 0.014
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.057 0.0511
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0438 0.9379 1
Trypanosoma brucei protein kinase, putative 0.0108 0.2058 0.2194
Loa Loa (eye worm) hypothetical protein 0.0021 0.0146 0.014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0148 0.0092
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.057 0.0564
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0326 0.025
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.4242 0.4238
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0095 0.0089
Brugia malayi MAP kinase sur-1 0.0108 0.2058 0.2053
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0148 0.0142
Onchocerca volvulus 0.0024 0.0191 0.0202
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0108 0.2058 0.2194
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0462 0.0903
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.057 0.0511
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0462 0.0903
Brugia malayi tailless protein 0.0019 0.0095 0.0089
Brugia malayi Cytochrome P450 family protein 0.0084 0.1541 0.1536
Echinococcus granulosus lamin dm0 0.0028 0.0297 0.0217
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0148 0.0058
Leishmania major protein kinase, putative 0.0438 0.9379 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0982 0.3495
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0108 0.2058 0.2142
Mycobacterium ulcerans beta-lactamase 0.0036 0.0462 0.1523
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.057 0.0511
Onchocerca volvulus 0.0036 0.0462 0.0768
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0326 0.025
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0128 0.0036
Schistosoma mansoni hypothetical protein 0.0176 0.3566 0.3739
Brugia malayi MH2 domain containing protein 0.0124 0.2415 0.2411
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0124 0.2408 0.2491
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0191 0.0186
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0084 0.1541 0.3206
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0191 0.0499
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0197 0.4025 0.4253
Mycobacterium ulcerans hypothetical protein 0.0024 0.0191 0.0499
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0084 0.1541 0.3206
Giardia lamblia DINP protein human, muc B family 0.0022 0.0148 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.057 0.0564
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0084 0.1541 0.5613
Brugia malayi hypoxia-induced factor 1 0.0148 0.2948 0.2944
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0089
Plasmodium falciparum protein serine/threonine kinase-1 0.0438 0.9379 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.006 0.0045
Echinococcus multilocularis musashi 0.0028 0.0297 0.0217
Onchocerca volvulus 0.0041 0.057 0.0994
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0148 0.0058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.057 0.0564
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0462 0.0395
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0146 0.014
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0297 0.0291
Brugia malayi steroid hormone receptor 0.0041 0.057 0.0564
Echinococcus granulosus dna polymerase eta 0.0022 0.0148 0.0058
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.057 0.0511
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0455 0.0449
Loa Loa (eye worm) hypothetical protein 0.0036 0.0462 0.0456
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0982 0.3495
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0148 0.0158
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0191 0.0326
Onchocerca volvulus 0.0021 0.0128 0.007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.132 0.135
Giardia lamblia Kinase, CMGC MAPK 0.0108 0.2058 0.2114
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0191 0.0245
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0084 0.1541 0.5613
Brugia malayi Cytochrome P450 family protein 0.0137 0.2698 0.2694
Loa Loa (eye worm) hypothetical protein 0.0036 0.0462 0.0456
Echinococcus multilocularis dual specificity 0.0197 0.4025 0.4233
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0462 0.0456
Onchocerca volvulus 0.0028 0.0297 0.0422
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0137 0.2698 1
Brugia malayi hypothetical protein 0.0021 0.0128 0.0122
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0462 0.0395
Loa Loa (eye worm) hypothetical protein 0.0021 0.0128 0.0122
Loa Loa (eye worm) hypothetical protein 0.0041 0.057 0.0564
Brugia malayi conserved hypotetical protein 0.0019 0.0095 0.0089
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0462 0.0903
Echinococcus granulosus lamin 0.0028 0.0297 0.0217
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0084 0.1541 0.3206
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0467 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0462 0.0428
Onchocerca volvulus 0.0021 0.0128 0.007
Schistosoma mansoni thyroid hormone receptor 0.0041 0.057 0.0511
Toxoplasma gondii ABC1 family protein 0.0036 0.0462 0.0395
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.057 0.0564
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0128 0.0122
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0084 0.1541 0.5613
Brugia malayi hypothetical protein 0.0019 0.0095 0.0089
Schistosoma mansoni lamin 0.0028 0.0297 0.0217
Loa Loa (eye worm) hypothetical protein 0.0022 0.0148 0.0142
Brugia malayi hypothetical protein 0.0021 0.0128 0.0122
Plasmodium vivax SET domain protein, putative 0.003 0.0326 0.0286
Leishmania major protein kinase, putative 0.0438 0.9379 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.057 0.0564
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0084 0.1541 0.5613
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0455 0.1496
Schistosoma mansoni coup transcription factor 0.0041 0.057 0.0511
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0462 0.0903
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.057 0.0511
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0084 0.1541 0.3206
Loa Loa (eye worm) hypothetical protein 0.0021 0.0128 0.0122
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.057 0.0511
Brugia malayi nuclear receptor NHR-88 0.0041 0.057 0.0564
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0191 0.0326
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.2058 0.2142
Echinococcus granulosus ubiquitin specific protease 41 0.0074 0.132 0.132
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0095 0.0089
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0095 0.0089
Entamoeba histolytica protein kinase domain containing protein 0.0197 0.4025 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0462 0.0903
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.006 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0462 0.0428
Brugia malayi Pre-SET motif family protein 0.0206 0.4242 0.4238
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0297 0.0291
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0462 0.0903
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0148 0.0158
Loa Loa (eye worm) hypothetical protein 0.0052 0.0828 0.0823
Brugia malayi Protein kinase domain containing protein 0.0197 0.4025 0.4021
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0074 0.132 0.132
Schistosoma mansoni hypothetical protein 0.0084 0.1541 0.1557
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0462 0.0395
Brugia malayi hypothetical protein 0.0021 0.0146 0.014
Schistosoma mansoni thyroid hormone receptor 0.0041 0.057 0.0511
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0146 0.0055
Onchocerca volvulus 0.0035 0.0455 0.0753
Echinococcus multilocularis lamin dm0 0.0028 0.0297 0.0217
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.057 0.0511
Brugia malayi ecdysteroid receptor 0.0041 0.057 0.0564
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.1161 0.1148
Trypanosoma cruzi cytochrome P450, putative 0.0137 0.2698 0.2829
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.0982 0.0956
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.0054
Brugia malayi nuclear receptor NHR-88 0.0019 0.0095 0.0089
Echinococcus multilocularis ubiquitin specific protease 41 0.0074 0.132 0.132
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0095 0.0089
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.057 0.0511
Echinococcus multilocularis 0.0433 0.9263 0.9875
Schistosoma mansoni rab6-interacting 0.0021 0.0128 0.0036
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0084 0.1541 0.5613
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0326 0.025
Mycobacterium ulcerans lipase LipD 0.0036 0.0462 0.1523
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0128 0.0073
Mycobacterium leprae Conserved hypothetical protein 0.0084 0.1541 1
Echinococcus multilocularis mitogen activated protein kinase 0.0108 0.2058 0.2115
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.0054
Loa Loa (eye worm) hypothetical protein 0.0041 0.057 0.0564
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0128 0.0036
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0148 0.0058
Loa Loa (eye worm) cytochrome P450 family protein 0.0137 0.2698 0.2694
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.057 0.0564

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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