Detailed information for compound 1582328

Basic information

Technical information
  • TDR Targets ID: 1582328
  • Name: N-methyl-N-(3-methyl-1,1-dioxothiolan-3-yl)cy clohexanecarboxamide
  • MW: 273.392 | Formula: C13H23NO3S
  • H donors: 0 H acceptors: 3 LogP: 1.56 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N(C1(C)CCS(=O)(=O)C1)C)C1CCCCC1
  • InChi: 1S/C13H23NO3S/c1-13(8-9-18(16,17)10-13)14(2)12(15)11-6-4-3-5-7-11/h11H,3-10H2,1-2H3
  • InChiKey: GXTVIDGEFIZAGX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-methyl-N-(3-methyl-1,1-dioxo-thiolan-3-yl)cyclohexanecarboxamide
  • N-methyl-N-(3-methyl-1,1-dioxo-3-thiolanyl)cyclohexanecarboxamide
  • N-(1,1-diketo-3-methyl-thiolan-3-yl)-N-methyl-cyclohexanecarboxamide
  • T5474389

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni neuropeptide receptor 0.0081 0.0256 0.0265
Treponema pallidum uridine phosphorylase (udp) 0.0193 0.0885 0.5
Loa Loa (eye worm) neuropeptide F receptor 0.0081 0.0256 0.0265
Echinococcus granulosus histone deacetylase 1 0.0472 0.2464 0.2629
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0953 0.0952
Schistosoma mansoni hypothetical protein 0.0098 0.0349 0.0365
Echinococcus multilocularis metastasis associated protein MTA1 0.0056 0.0111 0.0118
Onchocerca volvulus 0.0081 0.0256 0.0249
Plasmodium vivax histone deacetylase, putative 0.0395 0.203 0.3208
Brugia malayi Disco-interacting protein 2 homolog 0.0482 0.2518 0.2686
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0252 0.122 0.1219
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0081 0.0256 0.0273
Trypanosoma cruzi transcription elongation factor s-II, putative 0.0134 0.0552 0.0885
Trypanosoma brucei Aph-1 protein, putative 0.0661 0.3528 0.5657
Trypanosoma brucei uridine phosphorylase 0.0193 0.0885 0.1419
Echinococcus multilocularis neurogenic locus notch protein 0.0664 0.3549 0.3786
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0193 0.0885 0.0884
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Echinococcus multilocularis purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Echinococcus multilocularis histone lysine n methyltransferase suv420h1 0.0155 0.0675 0.072
Schistosoma mansoni hypothetical protein 0.0081 0.0256 0.0265
Onchocerca volvulus 0.0452 0.2348 0.2343
Schistosoma mansoni neuropeptide receptor 0.0081 0.0256 0.0265
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0109 0.0415 0.0408
Echinococcus granulosus uridine phosphorylase 1 0.0193 0.0885 0.0944
Loa Loa (eye worm) neuropeptide F receptor 0.0081 0.0256 0.0265
Echinococcus granulosus g protein coupled receptor 0.0081 0.0256 0.0273
Trypanosoma cruzi histone deacetylase, putative 0.0196 0.0904 0.1449
Onchocerca volvulus 0.0081 0.0256 0.0249
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0043 0.0038
Echinococcus granulosus metastasis associated protein 1 mta1 0.0056 0.0111 0.0118
Echinococcus multilocularis disco interacting protein 2 0.0482 0.2518 0.2686
Brugia malayi histone deacetylase 11 0.0196 0.0904 0.0963
Echinococcus multilocularis SET and MYND domain containing protein 3 0.008 0.0248 0.0265
Toxoplasma gondii histone deacetylase HDAC5 0.0196 0.0904 0.1503
Trypanosoma brucei histone deacetylase 1 0.0472 0.2464 0.395
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0663 0.3541 0.3778
Leishmania major hypothetical protein, conserved 0.0134 0.0552 0.0845
Loa Loa (eye worm) hypothetical protein 0.1017 0.554 0.5907
Loa Loa (eye worm) hypothetical protein 0.0043 0.0043 0.0038
Schistosoma mansoni jumonji domain containing protein 0.0086 0.0282 0.0293
Brugia malayi hypothetical protein 0.0098 0.0349 0.0372
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0953 0.0952
Echinococcus granulosus jumonji domain containing protein 0.0046 0.0056 0.006
Leishmania major nucleoside phosphorylase-like protein 0.0193 0.0885 0.1382
Loa Loa (eye worm) histone deacetylase 1 0.0472 0.2464 0.2623
Trypanosoma brucei histone-lysine n-methyltransferase 0.0203 0.0944 0.1514
Schistosoma mansoni amine GPCR 0.0081 0.0256 0.0265
Brugia malayi RE15519p 0.0081 0.0256 0.0272
Onchocerca volvulus 0.0482 0.2518 0.2513
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0177 0.0796 0.1315
Plasmodium falciparum histone deacetylase, putative 0.0395 0.203 0.3082
Echinococcus granulosus sex peptide receptor 0.0081 0.0256 0.0273
Schistosoma mansoni hypothetical protein 0.0134 0.0552 0.0582
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0043 0.0038
Schistosoma mansoni hypothetical protein 0.0081 0.0256 0.0265
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.1015 0.1014
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.1366 0.274
Echinococcus granulosus g-protein coupled receptor 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0663 0.3541 0.5567
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0165 0.0726 0.0775
Loa Loa (eye worm) hypothetical protein 0.0078 0.0237 0.0245
Trypanosoma brucei spermidine synthase 0.114 0.6237 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0077 0.0233 0.0333
Echinococcus granulosus tm gpcr rhodopsin 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0043 0.0043 0.0038
Echinococcus granulosus geminin 0.0205 0.0953 0.1016
Brugia malayi G protein-coupled receptor 0.0081 0.0256 0.0272
Brugia malayi beta-lactamase 0.0043 0.0043 0.0045
Mycobacterium tuberculosis Probable spermidine synthase SpeE (putrescine aminopropyltransferase) (aminopropyltransferase) (SPDSY) 0.0899 0.4872 1
Toxoplasma gondii histone deacetylase HDAC3 0.0472 0.2464 0.4225
Onchocerca volvulus Histone deacetylase 10 homolog 0.0196 0.0904 0.0898
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0081 0.0256 0.0273
Echinococcus granulosus histone lysine methyltransferase setb 0.0244 0.1177 0.1256
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Brugia malayi SET domain containing protein 0.0138 0.0576 0.0614
Brugia malayi hypothetical protein 0.1162 0.6356 0.6781
Loa Loa (eye worm) hypothetical protein 0.0472 0.2464 0.2623
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0256 0.0273
Leishmania major histone deacetylase, putative 0.0395 0.203 0.3225
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0081 0.0256 0.0273
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0081 0.0256 0.0272
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.1015 0.1014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Entamoeba histolytica hypothetical protein 0.0193 0.0885 0.2499
Leishmania major histone deacetylase, putative 0.0472 0.2464 0.3924
Trichomonas vaginalis Nicastrin precursor, putative 0.0098 0.0349 0.0348
Echinococcus multilocularis purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Echinococcus granulosus G protein coupled receptor 139 0.0081 0.0256 0.0273
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0043 0.0042
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0081 0.0256 0.0273
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1646 0.9091 0.9699
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0081 0.0256 0.0273
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0081 0.0256 0.0272
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0244 0.1177 0.1249
Trypanosoma cruzi histone deacetylase, putative 0.0395 0.203 0.3255
Schistosoma mansoni microtubule-associated protein tau 0.0785 0.4232 0.4511
Echinococcus granulosus purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Brugia malayi hypothetical protein 0.0385 0.1969 0.21
Echinococcus multilocularis adenosylhomocysteinase 0.0252 0.122 0.1302
Loa Loa (eye worm) hypothetical protein 0.0056 0.0111 0.0111
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0193 0.0885 0.0884
Echinococcus multilocularis protein arginine N methyltransferase 5 0.0064 0.0156 0.0166
Toxoplasma gondii phosphorylase family protein 0.0193 0.0885 0.147
Echinococcus multilocularis histone deacetylase 0.0395 0.203 0.2166
Loa Loa (eye worm) hypothetical protein 0.0067 0.0177 0.0182
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0201 0.093 0.0929
Mycobacterium tuberculosis Conserved hypothetical protein 0.0193 0.0885 0.1744
Schistosoma mansoni adenosylhomocysteinase 0.0252 0.122 0.1295
Trichomonas vaginalis set domain proteins, putative 0.1807 1 1
Plasmodium vivax histone deacetylase 1, putative 0.0472 0.2464 0.3908
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0193 0.0885 0.0884
Trypanosoma brucei presenilin-like aspartic peptidase, putative 0.0201 0.093 0.1491
Brugia malayi hypothetical protein 0.0081 0.0256 0.0272
Loa Loa (eye worm) hypothetical protein 0.0122 0.0486 0.0511
Echinococcus granulosus neuropeptide s receptor 0.0081 0.0256 0.0273
Schistosoma mansoni polybromo-1 0.0056 0.0111 0.0111
Mycobacterium leprae probable uridine phosphorylase 0.0193 0.0885 0.7154
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0201 0.093 0.0929
Echinococcus granulosus tm gpcr rhodopsin 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0046 0.0059 0.0055
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0472 0.2464 0.2463
Echinococcus multilocularis cpg binding protein 0.0454 0.2359 0.2516
Echinococcus multilocularis allatostatin A receptor 0.0081 0.0256 0.0273
Onchocerca volvulus 0.0081 0.0256 0.0249
Brugia malayi beta-lactamase family protein 0.0043 0.0043 0.0045
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.104 0.5673 0.9095
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0193 0.0885 0.5
Echinococcus granulosus neuropeptide FF receptor 2 0.0081 0.0256 0.0273
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0081 0.0256 0.0272
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0043 0.0045
Entamoeba histolytica presenilin 1 peptidase, putative 0.0201 0.093 0.2625
Echinococcus multilocularis peregrin 0.0167 0.0738 0.0787
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0472 0.2464 0.2463
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Trypanosoma brucei histone deacetylase, putative 0.0395 0.203 0.3255
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.015 0.0642 0.0685
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0663 0.3541 0.5678
Echinococcus granulosus PWWP domain containing protein 2A 0.0134 0.0552 0.0589
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0193 0.0885 0.0879
Schistosoma mansoni hypothetical protein 0.0205 0.0953 0.101
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1558 0.1558
Trypanosoma brucei transcription elongation factor s-II, putative 0.0134 0.0552 0.0885
Plasmodium falciparum spermidine synthase 0.114 0.6237 1
Loa Loa (eye worm) histone deacetylase 11 0.0196 0.0904 0.0958
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Echinococcus granulosus tm gpcr rhodopsin 0.0081 0.0256 0.0273
Schistosoma mansoni neuropeptide receptor 0.0081 0.0256 0.0265
Brugia malayi histone deacetylase 1 (HD1) 0.0472 0.2464 0.2628
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0056 0.0111 0.0111
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1558 0.1558
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Echinococcus granulosus methylthioadenosine phosphorylase 0.104 0.5673 0.6052
Loa Loa (eye worm) G-protein coupled receptor 0.0081 0.0256 0.0265
Echinococcus multilocularis uridine phosphorylase 1 0.0193 0.0885 0.0944
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1558 0.1558
Echinococcus multilocularis hepatoma derived growth factor protein 0.0134 0.0552 0.0589
Schistosoma mansoni hepatoma derived growth factor 0.0134 0.0552 0.0582
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0256 0.0265
Trichomonas vaginalis histone deacetylase, putative 0.0472 0.2464 0.2463
Echinococcus granulosus histone lysine N methyltransferase Ez 0.0334 0.1685 0.1797
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0046 0.0059 0.0055
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0081 0.0256 0.0265
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.1696 0.9373 1
Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase 0.0333 0.168 0.2506
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0193 0.0885 0.0884
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0256 0.0265
Echinococcus multilocularis Nicastrin 0.0098 0.0349 0.0373
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0953 0.0952
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0081 0.0256 0.0265
Echinococcus multilocularis histone deacetylase 6 0.0402 0.2065 0.2203
Loa Loa (eye worm) presenilin spe-4 0.007 0.0194 0.02
Loa Loa (eye worm) hypothetical protein 0.0482 0.2518 0.2681
Toxoplasma gondii Purine nucleoside phosphorylase 0.0193 0.0885 0.147
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0482 0.2518 0.2681
Onchocerca volvulus Neurogenic locus notch homolog 0.0664 0.3549 0.3545
Loa Loa (eye worm) hypothetical protein 0.0041 0.0031 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0092 0.009
Trichomonas vaginalis histone deacetylase, putative 0.0472 0.2464 0.2463
Echinococcus granulosus neuropeptide receptor 0.0081 0.0256 0.0273
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0049 0.0072 0.0076
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Entamoeba histolytica hypothetical protein 0.0067 0.0177 0.05
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0081 0.0256 0.0273
Onchocerca volvulus 0.0385 0.1969 0.1963
Echinococcus granulosus alpha 1A adrenergic receptor 0.0081 0.0256 0.0273
Trypanosoma brucei Presenilin enhancer-2 subunit of gamma secretase, putative 0.0057 0.0117 0.0188
Trypanosoma cruzi spermidine synthase, putative 0.114 0.6237 1
Loa Loa (eye worm) hypothetical protein 0.0385 0.1969 0.2094
Onchocerca volvulus 0.0081 0.0256 0.0249
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Trypanosoma cruzi Aph-1 protein, putative 0.0661 0.3528 0.5657
Brugia malayi hypothetical protein 0.0385 0.1969 0.21
Toxoplasma gondii sushi domain (scr repeat) domain-containing protein 0.0063 0.0153 0.0193
Echinococcus granulosus notch 0.008 0.0249 0.0266
Schistosoma mansoni histone J3 methyltransferase 0.16 0.8833 0.9424
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0043 0.0043 0.0038
Loa Loa (eye worm) hypothetical protein 0.0041 0.0031 0.0025
Loa Loa (eye worm) hypothetical protein 0.1162 0.6356 0.6779
Toxoplasma gondii sushi domain (scr repeat) domain-containing protein 0.0063 0.0153 0.0193
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0252 0.122 0.1219
Loa Loa (eye worm) hypothetical protein 0.0043 0.0043 0.0038
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0092 0.009
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.0252 0.122 1
Brugia malayi beta-lactamase family protein 0.0043 0.0043 0.0045
Brugia malayi gamma-secretase subunit aph-1 0.1696 0.9373 1
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0663 0.3541 0.6105
Echinococcus granulosus microtubule associated protein 2 0.0785 0.4232 0.4515
Echinococcus multilocularis neuropeptide Y receptor 0.0081 0.0256 0.0273
Loa Loa (eye worm) Notch2 0.0418 0.2155 0.2293
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Chlamydia trachomatis AMP nucleosidase 0.0193 0.0885 0.5
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0639 0.3407 0.363
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0043 0.0042
Brugia malayi S-adenosylmethionine decarboxylase proenzyme 0.0684 0.3663 0.3907
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0081 0.0256 0.0273
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1558 0.1558
Schistosoma mansoni amine GPCR 0.0081 0.0256 0.0265
Schistosoma mansoni cpg binding protein 0.0452 0.2348 0.25
Trichomonas vaginalis histone deacetylase, putative 0.0472 0.2464 0.2463
Brugia malayi Tachykinin-like peptides receptor 99D 0.0081 0.0256 0.0272
Loa Loa (eye worm) hypothetical protein 0.0206 0.0958 0.1016
Schistosoma mansoni neuropeptide F-like receptor 0.0081 0.0256 0.0265
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0953 0.0952
Loa Loa (eye worm) histone deacetylase 3 0.0472 0.2464 0.2623
Brugia malayi Presenilin spe-4 0.007 0.0194 0.0206
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0193 0.0885 0.2499
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0057 0.0116 0.0117
Trichomonas vaginalis histone deacetylase, putative 0.0472 0.2464 0.2463
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Plasmodium falciparum adenosylhomocysteinase 0.0252 0.122 0.175
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Echinococcus multilocularis fmrfamide receptor 0.0081 0.0256 0.0273
Echinococcus granulosus serotonin receptor 0.0081 0.0256 0.0273
Entamoeba histolytica Skb1 methyltransferase, putative 0.0064 0.0156 0.044
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0193 0.0885 0.1419
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.0252 0.122 0.1901
Schistosoma mansoni purine nucleoside phosphorylase 0.0193 0.0885 0.0938
Onchocerca volvulus 0.0063 0.0153 0.0146
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.0022 0.0024
Echinococcus granulosus fmrfamide receptor 0.0081 0.0256 0.0273
Schistosoma mansoni suppressor of variegation 4-20-related 0.0155 0.0675 0.0713
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0663 0.3541 0.3774
Trichomonas vaginalis CDC6, putative 0.0056 0.0111 0.011
Leishmania major hypothetical protein, conserved 0.0043 0.0043 0.0025
Entamoeba histolytica hypothetical protein 0.0134 0.0552 0.1558
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0108 0.0407 0.0434
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0049 0.0072 0.0075
Echinococcus multilocularis histone h3 methyltransferase 0.16 0.8833 0.9424
Echinococcus granulosus neuropeptides capa receptor 0.0081 0.0256 0.0273
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0079 0.0244 0.0243
Schistosoma mansoni cpg binding protein 0.0454 0.2359 0.2511
Echinococcus granulosus spermidine synthase 0.114 0.6237 0.6655
Echinococcus granulosus biogenic amine 5HT receptor 0.0081 0.0256 0.0273
Echinococcus multilocularis sex peptide receptor 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0043 0.0043 0.0038
Onchocerca volvulus 0.0043 0.0043 0.0036
Echinococcus granulosus adenosylhomocysteinase 0.0252 0.122 0.1302
Toxoplasma gondii DNA methyltransferase 2, putative 0.0663 0.3541 0.6105
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0193 0.0885 0.1419
Echinococcus granulosus Nicastrin 0.0098 0.0349 0.0373
Schistosoma mansoni bromo adjacent homology domain containing 0.0056 0.0111 0.0111
Schistosoma mansoni histamine h1 receptor 0.0081 0.0256 0.0265
Echinococcus multilocularis protein arginine N methyltransferase 7 0.016 0.0699 0.0745
Toxoplasma gondii histone arginine methyltransferase PRMT5 0.0064 0.0156 0.0198
Echinococcus multilocularis orexin receptor type 2 0.0081 0.0256 0.0273
Echinococcus granulosus 7tm_1 domain containing protein 0.0081 0.0256 0.0273
Brugia malayi GATA zinc finger family protein 0.0056 0.0111 0.0118
Schistosoma mansoni hypothetical protein 0.0134 0.0552 0.0582
Toxoplasma gondii hypothetical protein 0.0203 0.0944 0.1573
Brugia malayi jmjC domain containing protein 0.0042 0.0033 0.0034
Trichomonas vaginalis esterase, putative 0.0043 0.0043 0.0042
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0108 0.0407 0.0434
Brugia malayi Dopamine receptor protein 2 0.0081 0.0256 0.0272
Loa Loa (eye worm) hypothetical protein 0.0128 0.0521 0.0549
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Brugia malayi Calcium binding EGF domain containing protein 0.0067 0.0173 0.0183
Schistosoma mansoni opsin-like receptor 0.0081 0.0256 0.0265
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0043 0.0038
Echinococcus granulosus neurogenic locus notch protein 4 0.0041 0.0031 0.0033
Schistosoma mansoni uridine phosphorylase 0.0193 0.0885 0.0938
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0663 0.3541 1
Loa Loa (eye worm) hypothetical protein 0.0134 0.0552 0.0582
Mycobacterium ulcerans spermidine synthase 0.0899 0.4872 0.8578
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0007
Trichomonas vaginalis shk1 kinase-binding protein, putative 0.0041 0.0027 0.0026
Brugia malayi hypothetical protein 0.0081 0.0256 0.0272
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Echinococcus granulosus slit 2 protein 0.0037 0.0007 0.0007
Brugia malayi SET domain containing protein 0.0155 0.0675 0.0719
Trypanosoma cruzi spermidine synthase, putative 0.114 0.6237 1
Brugia malayi notch-like transmembrane receptor 0.0639 0.3407 0.3634
Echinococcus granulosus hypothetical protein 0.0081 0.0256 0.0273
Trypanosoma brucei protein arginine n-methyltransferase 7 0.016 0.0699 0.112
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Echinococcus granulosus histone lysine n methyltransferase suv420h1 0.0155 0.0675 0.072
Brugia malayi hypothetical protein 0.0134 0.0552 0.0588
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Onchocerca volvulus Neuropeptide F receptor homolog 0.0081 0.0256 0.0249
Loa Loa (eye worm) Skb1 methyltransferase 0.0064 0.0156 0.0159
Echinococcus multilocularis serotonin receptor 0.0081 0.0256 0.0273
Echinococcus granulosus gamma secretase subunit aph 1 0.1696 0.9373 1
Onchocerca volvulus 0.0081 0.0256 0.0249
Echinococcus multilocularis histone deacetylase 3 0.0472 0.2464 0.2629
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0244 0.1177 0.1249
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0067 0.0177 0.0284
Brugia malayi Serotonin receptor 0.0081 0.0256 0.0272
Schistosoma mansoni cpg binding protein 0.0454 0.2359 0.2511
Brugia malayi gamma-secretase subunit pen-2 0.0188 0.086 0.0917
Loa Loa (eye worm) transmembrane cell adhesion receptor mua-3 0.005 0.0077 0.0075
Trypanosoma cruzi transcription elongation factor-like protein, putative 0.0134 0.0552 0.0885
Brugia malayi uridine phosphorylase family protein 0.0193 0.0885 0.0943
Onchocerca volvulus 0.0081 0.0256 0.0249
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.016 0.0699 0.1082
Schistosoma mansoni adenosylhomocysteinase 0.0156 0.0678 0.0716
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.104 0.5673 0.9095
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0081 0.0256 0.0265
Leishmania major hypothetical protein, conserved 0.0203 0.0944 0.1477
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1558 0.1558
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.104 0.5673 0.9095
Onchocerca volvulus 0.0043 0.0043 0.0036
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0193 0.0885 0.1419
Onchocerca volvulus 0.0046 0.0059 0.0052
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0256 0.0265
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Echinococcus multilocularis neuropeptide FF receptor 2 0.0081 0.0256 0.0273
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.0252 0.122 0.2438
Echinococcus granulosus histone deacetylase 7 0.0395 0.203 0.2166
Echinococcus multilocularis bromo adjacent y domain containing 1 0.0056 0.0111 0.0118
Trichomonas vaginalis histone deacetylase, putative 0.0472 0.2464 0.2463
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0201 0.093 0.1491
Onchocerca volvulus 0.0134 0.0552 0.0545
Echinococcus multilocularis neuropeptides capa receptor 0.0081 0.0256 0.0273
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0049 0.0072 0.0069
Echinococcus granulosus neurogenic locus protein delta 0.0037 0.0007 0.0007
Brugia malayi hypothetical protein 0.0081 0.0256 0.0272
Loa Loa (eye worm) hypothetical protein 0.0244 0.1177 0.1249
Brugia malayi Dopamine receptor protein 1 0.0081 0.0256 0.0272
Brugia malayi hypothetical protein 0.0081 0.0256 0.0272
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0684 0.3663 0.5872
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0177 0.0796 0.0843
Leishmania major histone deacetylase, putative 0.0472 0.2464 0.3924
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0663 0.3541 0.5648
Onchocerca volvulus 0.0081 0.0256 0.0249
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Schistosoma mansoni uridine phosphorylase 0.0193 0.0885 0.0938
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0081 0.0256 0.0265
Toxoplasma gondii hypothetical protein 0.007 0.0194 0.0264
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.016 0.0699 0.112
Brugia malayi hypothetical protein 0.0134 0.0552 0.0588
Brugia malayi Dopamine receptor 0.0081 0.0256 0.0272
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.104 0.5673 1
Brugia malayi G-protein coupled receptor 0.0081 0.0256 0.0272
Onchocerca volvulus 0.0063 0.0153 0.0146
Brugia malayi SET domain containing protein 0.0334 0.1685 0.1797
Brugia malayi sulfakinin receptor protein 0.1162 0.6356 0.6781
Brugia malayi neuropeptide F receptor 0.0081 0.0256 0.0272
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0041 0.0031 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0085 0.0275 0.0286
Schistosoma mansoni growth hormone secretagogue receptor 0.0081 0.0256 0.0265
Trypanosoma cruzi histone deacetylase 1, putative 0.0472 0.2464 0.395
Brugia malayi Presenilin family protein 0.0201 0.093 0.0991
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0081 0.0256 0.0265
Brugia malayi Histone deacetylase family protein 0.0395 0.203 0.2165
Leishmania major modification methylase-like protein 0.0663 0.3541 0.5659
Brugia malayi Histone-lysine N-methyltransferase, H3 lysine-79 specific 0.16 0.8833 0.9424
Trypanosoma cruzi spermidine synthase, putative 0.114 0.6237 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0244 0.1177 0.1256
Brugia malayi Protein arginine N-methyltransferase 0.016 0.0699 0.0744
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Onchocerca volvulus Neurogenic locus notch homolog 0.0063 0.0153 0.0146
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0081 0.0256 0.0273
Echinococcus multilocularis histone deacetylase 7 0.0395 0.203 0.2166
Brugia malayi hypothetical protein 0.0081 0.0256 0.0272
Echinococcus granulosus histone deacetylase 8 0.0196 0.0904 0.0964
Loa Loa (eye worm) jmjC domain-containing protein 0.0068 0.0182 0.0186
Schistosoma mansoni opsin-like receptor 0.0081 0.0256 0.0265
Toxoplasma gondii histone deacetylase HDAC4 0.0196 0.0904 0.1503
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0157 0.0682 0.1054
Brugia malayi neuropeptide F receptor 0.0081 0.0256 0.0272
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Toxoplasma gondii phosphorylase family protein 0.0193 0.0885 0.147
Trypanosoma cruzi Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0203 0.0944 0.1514
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.0033 0.0035
Leishmania major hypothetical protein, conserved 0.0057 0.0117 0.0145
Loa Loa (eye worm) protein arginine N-methyltransferase 0.016 0.0699 0.0738
Brugia malayi hypothetical protein 0.007 0.0194 0.0206
Echinococcus granulosus bromo adjacent y domain containing 1 0.0056 0.0111 0.0118
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0193 0.0885 0.0884
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0081 0.0256 0.0272
Echinococcus granulosus histone deacetylase 3 0.0472 0.2464 0.2629
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0199 0.0922 0.0984
Echinococcus granulosus neuropeptide Y receptor 0.0081 0.0256 0.0273
Schistosoma mansoni protein arginine n-methyltransferase 0.0127 0.0515 0.0542
Echinococcus multilocularis histone deacetylase 6 0.0395 0.203 0.2166
Brugia malayi MTAP 0.104 0.5673 0.6052
Schistosoma mansoni subfamily A22A unassigned peptidase (A22 family) 0.0201 0.093 0.0985
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.015 0.0642 0.0685
Schistosoma mansoni methylthioadenosine phosphorylase 0.104 0.5673 0.6049
Echinococcus multilocularis Nicastrin 0.0098 0.0349 0.0373
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0081 0.0256 0.0249
Toxoplasma gondii histone deacetylase HDAC2 0.0472 0.2464 0.4225
Echinococcus granulosus biogenic amine 5HT receptor 0.0081 0.0256 0.0273
Loa Loa (eye worm) gamma-secretase subunit pen-2 0.0188 0.086 0.0911
Schistosoma mansoni hypothetical protein 0.0056 0.0111 0.0111
Schistosoma mansoni histone deacetylase 1 2 3 0.0196 0.0904 0.0958
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.1558 0.1656
Toxoplasma gondii histone deacetylase HDAC1 0.0395 0.203 0.3468
Echinococcus granulosus neuropeptide receptor A26 0.0081 0.0256 0.0273
Brugia malayi EGF-like domain containing protein 0.0063 0.0153 0.0163
Onchocerca volvulus 0.0081 0.0256 0.0249
Brugia malayi larval opioid receptor 0.0081 0.0256 0.0272
Echinococcus granulosus hepatoma derived growth factor protein 0.0134 0.0552 0.0589
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0359 0.1824 0.194
Echinococcus multilocularis neuropeptide receptor 0.0081 0.0256 0.0273
Schistosoma mansoni neuropeptide receptor 0.0081 0.0256 0.0265
Trypanosoma cruzi histone deacetylase, putative 0.0196 0.0904 0.1449
Echinococcus multilocularis histone lysine n methyltransferase setb1 0.0038 0.0013 0.0014
Plasmodium vivax S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative 0.0333 0.168 0.2643
Echinococcus multilocularis G protein coupled receptor 139 0.0081 0.0256 0.0273
Echinococcus granulosus protein arginine N methyltransferase 5 0.0064 0.0156 0.0166
Echinococcus multilocularis somatostatin receptor 0.0081 0.0256 0.0273
Toxoplasma gondii hypothetical protein 0.1058 0.5774 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0111 0.0111
Echinococcus multilocularis PWWP domain containing protein 2A 0.0134 0.0552 0.0589
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0193 0.0885 0.136
Plasmodium vivax protein arginine N-methyltransferase 5, putative 0.0064 0.0156 0.0183
Echinococcus multilocularis microtubule associated protein 2 0.0785 0.4232 0.4515
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Brugia malayi Presenilin-like protein At2g29900 0.007 0.0194 0.0206
Echinococcus granulosus dro:myosuppressin receptor 0.0081 0.0256 0.0273
Brugia malayi putative neuropeptide receptor 0.0081 0.0256 0.0272
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Schistosoma mansoni amine GPCR 0.0081 0.0256 0.0265
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0067 0.0177 0.05
Schistosoma mansoni biogenic amine (5HT) receptor 0.0081 0.0256 0.0265
Schistosoma mansoni gamma-secretase subunit aph-1 0.1696 0.9373 1
Schistosoma mansoni hepatoma derived growth factor 0.0134 0.0552 0.0582
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0067 0.0173 0.0177
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0201 0.093 0.1491
Toxoplasma gondii hypothetical protein 0.0057 0.0117 0.013
Echinococcus multilocularis PWWP domain containing protein 2A 0.0134 0.0552 0.0589
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0684 0.3663 0.5872
Trichomonas vaginalis Nicastrin precursor, putative 0.0098 0.0349 0.0348
Brugia malayi hypothetical protein 0.007 0.0194 0.0206
Loa Loa (eye worm) hypothetical protein 0.16 0.8833 0.9424
Brugia malayi EGF-like domain containing protein 0.0351 0.1781 0.1899
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0081 0.0256 0.0273
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0081 0.0256 0.0273
Echinococcus granulosus protein arginine N methyltransferase 7 0.016 0.0699 0.0745
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.0193 0.0885 0.1744
Echinococcus granulosus allatostatin A receptor 0.0081 0.0256 0.0273
Echinococcus multilocularis S adenosylmethionine decarboxylase proenzyme 0.0684 0.3663 0.3907
Loa Loa (eye worm) hypothetical protein 0.0063 0.0153 0.0156
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0157 0.0682 0.0727
Schistosoma mansoni neuropeptide f receptor 76f 0.0081 0.0256 0.0265
Brugia malayi AKH receptor 0.0081 0.0256 0.0272
Loa Loa (eye worm) Carm1-pending protein 0.0165 0.0726 0.0768
Brugia malayi hypothetical protein 0.0067 0.0177 0.0188
Loa Loa (eye worm) histone deacetylase 0.0395 0.203 0.216
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0201 0.093 0.0929
Trichomonas vaginalis shk1 kinase-binding protein, putative 0.0041 0.0027 0.0026
Onchocerca volvulus 0.0134 0.0552 0.0545
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0081 0.0256 0.0265
Trichomonas vaginalis origin recognition complex subunit, putative 0.0056 0.0111 0.011
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0299 0.1485 0.1578
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0081 0.0256 0.0265
Echinococcus granulosus tachykinin peptides receptor 99D 0.0081 0.0256 0.0273
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0081 0.0256 0.0272
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0043 0.0046
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0081 0.0256 0.0273
Schistosoma mansoni enhancer of zeste ezh 0.0334 0.1685 0.1791
Toxoplasma gondii hypothetical protein 0.0134 0.0552 0.0888
Echinococcus multilocularis neuropeptide receptor A26 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0256 0.0273
Onchocerca volvulus 0.0081 0.0256 0.0249
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0684 0.3663 0.5872
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0081 0.0256 0.0265
Loa Loa (eye worm) TYRA-2 protein 0.0081 0.0256 0.0265
Loa Loa (eye worm) G-protein coupled receptor 0.0081 0.0256 0.0265
Trypanosoma cruzi spermidine synthase, putative 0.114 0.6237 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Schistosoma mansoni hypothetical protein 0.0134 0.0552 0.0582
Echinococcus multilocularis presenilin enhancer 2 0.0188 0.086 0.0918
Plasmodium falciparum histone deacetylase 1 0.0472 0.2464 0.3795
Trypanosoma cruzi histone deacetylase, putative 0.0395 0.203 0.3255
Echinococcus multilocularis dro:myosuppressin receptor 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Echinococcus multilocularis G-protein coupled receptor, putative 0.0081 0.0256 0.0273
Schistosoma mansoni biogenic amine (5HT) receptor 0.0081 0.0256 0.0265
Echinococcus multilocularis histone deacetylase 8 0.0196 0.0904 0.0964
Echinococcus multilocularis arginine glutamic acid dipeptide (RE) repeats 0.0056 0.0111 0.0118
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0043 0.0068
Onchocerca volvulus 0.0144 0.0612 0.0605
Loa Loa (eye worm) spermidine synthase 0.114 0.6237 0.6652
Brugia malayi SET domain containing protein 0.0073 0.0212 0.0225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0067 0.0177 0.0284
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0062 0.0145 0.0147
Trypanosoma brucei histone deacetylase 4 0.0395 0.203 0.3255
Schistosoma mansoni adenoreceptor 0.0081 0.0256 0.0265
Schistosoma mansoni neuropeptide F-like receptor 0.0081 0.0256 0.0265
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0098 0.0349 0.0365
Loa Loa (eye worm) PWWP domain-containing protein 0.0134 0.0552 0.0582
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0081 0.0256 0.0273
Brugia malayi Spermidine synthase 0.114 0.6237 0.6654
Brugia malayi Adenosylhomocysteinase 0.0252 0.122 0.1301
Brugia malayi hypothetical protein 0.0081 0.0256 0.0272
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0256 0.0265
Schistosoma mansoni hypothetical protein 0.0063 0.0153 0.0156
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0953 0.0952
Loa Loa (eye worm) hypothetical protein 0.0043 0.0043 0.0038
Schistosoma mansoni methylthioadenosine phosphorylase 0.0193 0.0885 0.0938
Loa Loa (eye worm) hypothetical protein 0.0057 0.0122 0.0122
Schistosoma mansoni histone deacetylase hda2 0.0196 0.0904 0.0958
Echinococcus granulosus histone lysine n methyltransferase setb1 0.0038 0.0013 0.0014
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0081 0.0256 0.0273
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0043 0.0042
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0081 0.0256 0.0273
Echinococcus multilocularis purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Loa Loa (eye worm) SET domain-containing protein 0.0334 0.1685 0.1791
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Brugia malayi hypothetical protein 0.007 0.0194 0.0206
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Onchocerca volvulus 0.0081 0.0256 0.0249
Echinococcus granulosus neurogenic locus notch protein 0.0664 0.3549 0.3786
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0193 0.0885 0.2499
Brugia malayi ORL1-like opioid receptor 0.0081 0.0256 0.0272
Echinococcus granulosus metastasis associated protein MTA1 0.0056 0.0111 0.0118
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0193 0.0885 0.7154
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Echinococcus multilocularis neuropeptide Y receptor 0.0081 0.0256 0.0273
Schistosoma mansoni notch 0.0269 0.1315 0.1397
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0056 0.0111 0.0111
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0252 0.122 0.1956
Brugia malayi follicle stimulating hormone receptor 0.0359 0.1824 0.1945
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.1558 0.1662
Onchocerca volvulus 0.0081 0.0256 0.0249
Brugia malayi Presenilin spe-4 0.007 0.0194 0.0206
Echinococcus multilocularis g-protein coupled receptor 0.0081 0.0256 0.0273
Schistosoma mansoni SET domain protein 0.0152 0.0653 0.069
Echinococcus granulosus DNA methyltransferase 2, putative 0.0663 0.3541 0.3778
Schistosoma mansoni shk1 kinase-binding protein 0.0064 0.0156 0.0159
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1558 0.1558
Leishmania major histone deacetylase, putative 0.0395 0.203 0.3225
Brugia malayi CXXC zinc finger family protein 0.0452 0.2348 0.2505
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.104 0.5673 0.6049
Leishmania major methylthioadenosine phosphorylase, putative 0.104 0.5673 0.9091
Echinococcus granulosus presenilin 0.0201 0.093 0.0992
Schistosoma mansoni histone deacetylase 0.0472 0.2464 0.2623
Plasmodium vivax SET domain protein, putative 0.0177 0.0796 0.1217
Echinococcus granulosus disco interacting protein 2 0.0482 0.2518 0.2686
Brugia malayi Carm1-pending protein 0.0165 0.0726 0.0774
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0193 0.0885 0.2499
Loa Loa (eye worm) uridine phosphorylase 0.0193 0.0885 0.0938
Echinococcus multilocularis metastasis associated protein 1 (mta1) 0.0056 0.0111 0.0118
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0193 0.0885 0.0943
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.1058 0.5774 0.9237
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0165 0.0726 0.1193
Echinococcus granulosus neuropeptide receptor 0.0081 0.0256 0.0273
Echinococcus granulosus cpg binding protein 0.0454 0.2359 0.2516
Brugia malayi G-protein coupled receptor 0.0081 0.0256 0.0272
Schistosoma mansoni histone deacetylase hda2 0.0402 0.2065 0.2197
Trypanosoma cruzi histone deacetylase 1, putative 0.0472 0.2464 0.395
Brugia malayi histone deacetylase 3 (HD3) 0.0472 0.2464 0.2628
Echinococcus multilocularis purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0056 0.0111 0.0111
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0081 0.0256 0.0273
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0256 0.0265
Onchocerca volvulus 0.0081 0.0256 0.0249
Echinococcus granulosus purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Trypanosoma brucei histone deacetylase 2 0.0196 0.0904 0.1449
Plasmodium vivax histone deacetylase 2, putative 0.0395 0.203 0.3208
Echinococcus granulosus polybromo 1 0.0056 0.0111 0.0118
Loa Loa (eye worm) hypothetical protein 0.0043 0.0043 0.0038
Toxoplasma gondii microneme protein MIC12 0.005 0.0077 0.006
Echinococcus multilocularis serotonin receptor 0.0081 0.0256 0.0273
Leishmania major histone-lysine N-methyltransferase, putative 0.0203 0.0944 0.1477
Toxoplasma gondii notch (dsl) domain-containing protein 0.0063 0.0153 0.0193
Brugia malayi PWWP domain containing protein 0.0134 0.0552 0.0588
Leishmania major S-adenosylhomocysteine hydrolase 0.0252 0.122 0.1921
Schistosoma mansoni biogenic amine receptor 0.0081 0.0256 0.0265
Schistosoma mansoni alpha-1 adrenergic receptor 0.0081 0.0256 0.0265
Echinococcus multilocularis spermidine synthase 0.114 0.6237 0.6655
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0256 0.0265
Treponema pallidum pfs protein (pfs) 0.0193 0.0885 0.5
Schistosoma mansoni phd finger protein 0.0134 0.0552 0.0582
Schistosoma mansoni purine nucleoside phosphorylase 0.0193 0.0885 0.0938
Trypanosoma cruzi histone deacetylase, putative 0.0395 0.203 0.3255
Trypanosoma cruzi arginine N-methyltransferase, type II, putative 0.0041 0.0027 0.0043
Echinococcus multilocularis geminin 0.0205 0.0953 0.1016
Entamoeba histolytica adenosylhomocysteinase, putative 0.0252 0.122 0.3445
Brugia malayi polybromodomain protein 0.0056 0.0111 0.0118
Echinococcus multilocularis neuropeptide s receptor 0.0081 0.0256 0.0273
Schistosoma mansoni notch 0.008 0.0249 0.0259
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Onchocerca volvulus 0.0081 0.0256 0.0249
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0033 0.0028
Echinococcus multilocularis neuropeptides capa receptor 0.0081 0.0256 0.0273
Loa Loa (eye worm) S-adenosylmethionine decarboxylase proenzyme 0.0684 0.3663 0.3903
Loa Loa (eye worm) hypothetical protein 0.0046 0.0059 0.0055
Echinococcus granulosus PWWP domain containing protein 2A 0.0134 0.0552 0.0589
Echinococcus granulosus g protein coupled receptor 0.0081 0.0256 0.0273
Onchocerca volvulus 0.0043 0.0043 0.0036
Echinococcus granulosus neuropeptides capa receptor 0.0081 0.0256 0.0273
Loa Loa (eye worm) histone deacetylase 7A 0.0395 0.203 0.216
Giardia lamblia Histone deacetylase 0.0472 0.2464 1
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0193 0.0885 0.0884
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.0199 0.0923 0.0978
Schistosoma mansoni adenosylhomocysteinase 0.0156 0.0678 0.0716
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0081 0.0256 0.0265
Schistosoma mansoni protein arginine n-methyltransferase 0.0165 0.0726 0.0768
Brugia malayi Pre-SET motif family protein 0.1646 0.9091 0.9699
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Brugia malayi G protein-coupled receptor F59B2.13 0.0081 0.0256 0.0272
Brugia malayi Histone deacetylase 1 0.0472 0.2464 0.2628
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0193 0.0885 0.0884
Echinococcus granulosus histone deacetylase 0.0395 0.203 0.2166
Plasmodium falciparum histone deacetylase 2 0.0395 0.203 0.3082
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0081 0.0256 0.0265
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0081 0.0256 0.0273
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0885 0.0884
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0046 0.0059 0.0062
Plasmodium vivax histone-lysine N-methyltransferase, putative 0.0096 0.0339 0.0478
Onchocerca volvulus 0.0299 0.1485 0.1479
Echinococcus granulosus purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Echinococcus multilocularis polybromo 1 0.0056 0.0111 0.0118
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0043 0.0042
Trypanosoma brucei histone deacetylase 3 0.0395 0.203 0.3255
Trypanosoma cruzi Aph-1 protein, putative 0.0661 0.3528 0.5657
Trichomonas vaginalis histone deacetylase, putative 0.0472 0.2464 0.2463
Schistosoma mansoni adenosylhomocysteinase 0.0156 0.0678 0.0716
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.0953 0.0946
Trypanosoma brucei arginine N-methyltransferase, type II 0.0041 0.0027 0.0043
Loa Loa (eye worm) hypothetical protein 0.1017 0.554 0.5907
Echinococcus multilocularis presenilin 0.0201 0.093 0.0992
Leishmania major hypothetical protein, conserved 0.0203 0.0944 0.1477
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0193 0.0885 0.2499
Mycobacterium tuberculosis Hypothetical protein 0.0193 0.0885 0.1744
Brugia malayi NNMT/PNMT/TEMT family protein 0.1017 0.554 0.591
Echinococcus granulosus orexin receptor type 2 0.0081 0.0256 0.0273
Echinococcus granulosus purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0081 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Onchocerca volvulus 0.0081 0.0256 0.0249
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0472 0.2464 0.2463
Plasmodium falciparum histone-lysine N-methyltransferase, putative 0.0096 0.0339 0.0301
Echinococcus multilocularis histone deacetylase 6 0.0395 0.203 0.2166
Echinococcus granulosus histone h3 methyltransferase 0.16 0.8833 0.9424
Echinococcus granulosus peptide allatostatin:somatostatin 0.0081 0.0256 0.0273
Echinococcus multilocularis fmrfamide receptor 0.0081 0.0256 0.0273
Echinococcus granulosus neuropeptide Y receptor 0.0081 0.0256 0.0273
Schistosoma mansoni methylthioadenosine phosphorylase 0.104 0.5673 0.6049
Echinococcus multilocularis purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0081 0.0256 0.0273
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0193 0.0885 0.1496
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0056 0.0111 0.0111
Schistosoma mansoni biogenic amine receptor 0.0081 0.0256 0.0265
Trypanosoma cruzi hypothetical protein, conserved 0.0134 0.0552 0.0885
Echinococcus granulosus peregrin 0.0167 0.0738 0.0787
Trypanosoma brucei Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0203 0.0944 0.1514
Onchocerca volvulus 0.0081 0.0256 0.0249
Plasmodium vivax spermidine synthase, putative 0.114 0.6237 1
Echinococcus granulosus presenilin enhancer 2 0.0188 0.086 0.0918
Echinococcus granulosus purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Schistosoma mansoni histone deacetylase 4 5 0.0395 0.203 0.216
Loa Loa (eye worm) hypothetical protein 0.0196 0.0904 0.0958
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0043 0.0042
Brugia malayi Pre-SET motif family protein 0.0215 0.1013 0.108
Brugia malayi jmjC domain containing protein 0.0108 0.0407 0.0433
Loa Loa (eye worm) adenosylhomocysteinase 0.0252 0.122 0.1295
Brugia malayi Histone deacetylase family protein 0.0395 0.203 0.2165
Onchocerca volvulus 0.0081 0.0256 0.0249
Toxoplasma gondii adenosylhomocysteinase, putative 0.0252 0.122 0.2054
Schistosoma mansoni amine GPCR 0.0081 0.0256 0.0265
Echinococcus granulosus SET and MYND domain containing protein 3 0.008 0.0248 0.0265
Brugia malayi EGF-like domain containing protein 0.0037 0.0007 0.0006
Leishmania major presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative 0.0201 0.093 0.1454
Loa Loa (eye worm) hypothetical protein 0.0056 0.0111 0.0111
Echinococcus granulosus arginine glutamic acid dipeptide RE repeats 0.0056 0.0111 0.0118
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0193 0.0885 0.0884
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0256 0.0273
Loa Loa (eye worm) SET domain-containing protein 0.0155 0.0675 0.0713
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0953 0.0952
Trypanosoma brucei S-adenosylmethionine decarboxylase proenzyme, putative 0.0684 0.3663 0.5872
Echinococcus granulosus 7TM GPCR rhodopsin 0.0081 0.0256 0.0273
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0033 0.0028
Trypanosoma cruzi histone-lysine N-methyltransferase, putative 0.0203 0.0944 0.1514
Mycobacterium tuberculosis Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) 0.0848 0.4585 0.9405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0256 0.0265
Brugia malayi hypothetical protein 0.0098 0.0349 0.0372
Schistosoma mansoni histone deacetylase 0.0472 0.2464 0.2623
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0043 0.0046
Loa Loa (eye worm) CXXC zinc finger family protein 0.0452 0.2348 0.25
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0203 0.0944 0.1514
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0049 0.0072 0.0076
Echinococcus multilocularis jumonji domain containing protein 0.0046 0.0056 0.006
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0193 0.0885 0.1744
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0067 0.0177 0.0284
Loa Loa (eye worm) notch protein 0.0067 0.0173 0.0177
Loa Loa (eye worm) hypothetical protein 0.0385 0.1969 0.2094
Schistosoma mansoni biogenic amine receptor 0.0081 0.0256 0.0265
Schistosoma mansoni amine GPCR 0.0081 0.0256 0.0265
Schistosoma mansoni hypothetical protein 0.0059 0.013 0.0131
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0256 0.0265
Echinococcus granulosus purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Echinococcus multilocularis neurogenic locus protein delta 0.0037 0.0007 0.0007
Echinococcus multilocularis neuropeptide receptor 0.0081 0.0256 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0043 0.0068
Echinococcus multilocularis purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Brugia malayi Melatonin receptor type 1A 0.0081 0.0256 0.0272
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0203 0.0944 0.1514
Trypanosoma cruzi MIZ/SP-RING zinc finger, putative 0.0134 0.0552 0.0885
Echinococcus granulosus sodium channel protein 0.0157 0.0682 0.0727
Echinococcus granulosus somatostatin receptor 0.0081 0.0256 0.0273
Schistosoma mansoni histone deacetylase 4 5 0.0395 0.203 0.216
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Echinococcus granulosus histone deacetylase 6 0.0395 0.203 0.2166
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0256 0.0265
Echinococcus granulosus purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Trypanosoma brucei Histone methylation protein DOT1, putative 0.0203 0.0944 0.1514
Entamoeba histolytica histone deacetylase, putative 0.0472 0.2464 0.6957
Echinococcus granulosus g protein coupled receptor 0.0081 0.0256 0.0273
Echinococcus granulosus purine nucleoside phosphorylase 0.0193 0.0885 0.0944
Brugia malayi Calcium binding EGF domain containing protein 0.0067 0.0173 0.0183
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0177 0.0796 0.085
Brugia malayi GnHR receptor homolog 0.0081 0.0256 0.0272
Echinococcus multilocularis notch 0.008 0.0249 0.0266
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0193 0.0885 0.2499
Brugia malayi hypothetical protein 0.0081 0.0256 0.0272
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.0193 0.0885 0.1496
Schistosoma mansoni opsin-like receptor 0.0081 0.0256 0.0265
Brugia malayi putative neuropeptide receptor NPR1 0.0081 0.0256 0.0272
Brugia malayi Skb1 methyltransferase family protein 0.0064 0.0156 0.0165
Brugia malayi Presenilin spe-4 0.007 0.0194 0.0206
Leishmania major S-adenosylmethionine decarboxylase 0.0684 0.3663 0.5854
Schistosoma mansoni adenosylhomocysteinase 0.0156 0.0678 0.0716
Plasmodium falciparum purine nucleoside phosphorylase 0.0193 0.0885 0.1199
Brugia malayi ELM2 domain containing protein 0.0056 0.0111 0.0118
Brugia malayi hypothetical protein 0.0081 0.0256 0.0272
Loa Loa (eye worm) NNMT/PNMT/TEMT family protein 0.1017 0.554 0.5907
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0081 0.0256 0.0265
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.0252 0.122 0.2091
Loa Loa (eye worm) hypothetical protein 0.0385 0.1969 0.2094
Echinococcus multilocularis gamma secretase subunit aph 1 0.1696 0.9373 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Brugia malayi Serotonin receptor 0.0081 0.0256 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0885 0.0884
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0953 0.0952
Trypanosoma cruzi hypothetical protein, conserved 0.0134 0.0552 0.0885
Plasmodium vivax histone deacetylase, putative 0.0196 0.0904 0.139
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0684 0.3663 0.5872
Loa Loa (eye worm) hypothetical protein 0.0067 0.0173 0.0177
Onchocerca volvulus 0.0081 0.0256 0.0249
Schistosoma mansoni myosin xvIII 0.0081 0.0256 0.0265
Echinococcus granulosus histone deacetylase 6 0.0402 0.2065 0.2203
Loa Loa (eye worm) beta-lactamase 0.0043 0.0043 0.0038
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0165 0.0726 0.0775
Echinococcus multilocularis histone lysine N methyltransferase E(z) 0.0334 0.1685 0.1797
Loa Loa (eye worm) melatonin receptor type 1A 0.0081 0.0256 0.0265
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0193 0.0885 0.2499
Brugia malayi hypothetical protein 0.0081 0.0256 0.0272
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0252 0.122 0.1956
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.0252 0.122 0.2054
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0043 0.0068
Echinococcus multilocularis neurogenic locus notch protein 4 0.0041 0.0031 0.0033
Echinococcus multilocularis slit 2 protein 0.0037 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0081 0.0256 0.0265
Echinococcus multilocularis methylthioadenosine phosphorylase 0.104 0.5673 0.6052
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0033 0.0028
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0081 0.0256 0.0273
Leishmania major spermidine synthase 0.114 0.6237 1
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.0252 0.122 0.1956
Echinococcus multilocularis histone deacetylase 1 0.0472 0.2464 0.2629
Schistosoma mansoni hypothetical protein 0.0081 0.0256 0.0265
Trypanosoma cruzi arginine N-methyltransferase, type III 0.016 0.0699 0.112
Echinococcus granulosus histone deacetylase 6 0.0395 0.203 0.2166
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Echinococcus multilocularis sodium channel protein 0.0157 0.0682 0.0727
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0256 0.0273
Echinococcus granulosus S adenosylmethionine decarboxylase proenzyme 0.0684 0.3663 0.3907
Schistosoma mansoni hypothetical protein 0.0205 0.0953 0.101
Loa Loa (eye worm) hypothetical protein 0.0081 0.0256 0.0265
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0256 0.0265

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.2995 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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