Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | inositol 5-phosphatase 1, putative | 0.0017 | 0.0038 | 0.0047 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0003 | 0.0002 | 0.0002 |
Brugia malayi | Cytochrome P450 family protein | 0.005 | 0.0124 | 0.0124 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0333 | 0.0871 | 0.0871 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0028 | 0.0068 | 0.0066 |
Trypanosoma cruzi | endonuclease/exonuclease/phosphatase, putative | 0.0017 | 0.0038 | 0.0047 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0005 | 0.0006 | 0.0006 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0333 | 0.0871 | 0.116 |
Trypanosoma brucei | Endonuclease/Exonuclease/phosphatase family, putative | 0.0017 | 0.0038 | 0.0032 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0038 |
Trypanosoma brucei | Inositol phosphosphingolipids phospholipase C | 0.0017 | 0.0038 | 0.0032 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0034 | 0.0083 | 0.3389 |
Trypanosoma cruzi | cytochrome P450, putative | 0.005 | 0.0124 | 0.0161 |
Schistosoma mansoni | thyroid hormone receptor | 0.0047 | 0.0116 | 0.0115 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0038 | 0.0047 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0034 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0003 | 0.0002 | 0.0002 |
Schistosoma mansoni | neutral sphingomyelinase | 0.0017 | 0.0038 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0107 | 0.0105 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0034 | 0.0083 | 0.3389 |
Trypanosoma brucei | RNA editing exonuclease 2 | 0.0017 | 0.0038 | 0.0032 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0085 | 0.0217 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0025 | 0.0058 | 0.2171 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0034 | 0.0083 | 0.0107 |
Leishmania major | DNA topoisomerase IB, large subunit | 0.2841 | 0.7485 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0011 | 0.0021 | 0.0021 |
Onchocerca volvulus | Putative neutral sphingomyelinase | 0.0017 | 0.0038 | 0.5496 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0034 | 0.0083 | 0.3389 |
Echinococcus multilocularis | carbonic anhydrase | 0.0133 | 0.0343 | 0.0343 |
Mycobacterium tuberculosis | Probable exported protein | 0.0017 | 0.0038 | 0.1192 |
Trichomonas vaginalis | type II inositol 5-phosphatase, putative | 0.0017 | 0.0038 | 0.1638 |
Schistosoma mansoni | nocturnin | 0.0017 | 0.0038 | 0.0036 |
Leishmania major | inositol/phosphatidylinositol phosphatase, putative | 0.0017 | 0.0038 | 0.0047 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0034 | 0.0083 | 0.3389 |
Echinococcus granulosus | carbonic anhydrase | 0.0133 | 0.0343 | 0.0343 |
Plasmodium falciparum | exodeoxyribonuclease III, putative | 0.0017 | 0.0038 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.005 | 0.0124 | 0.0124 |
Onchocerca volvulus | 0.0009 | 0.0017 | 0.2303 | |
Leishmania major | inositol phosphosphingolipid phospholipase C-Like | 0.0017 | 0.0038 | 0.0047 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0034 | 0.0083 | 0.3389 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0004 | 0.0003 | 0.0003 |
Plasmodium falciparum | endonuclease/exonuclease/phosphatase family protein, putative | 0.0017 | 0.0038 | 0.0024 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0034 | 0.0083 | 0.3389 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0003 | 0.0002 | 0.0002 |
Schistosoma mansoni | cytochrome P450 | 0.0034 | 0.0083 | 0.0081 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0025 | 0.0058 | 0.2171 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0034 | 0.0083 | 0.3389 |
Echinococcus multilocularis | musashi | 0.0011 | 0.0021 | 0.0021 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0034 | 0.0083 | 0.3389 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0038 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0034 | 0.0083 | 0.3389 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0003 | 0.0002 | 0.0002 |
Echinococcus multilocularis | carbonic anhydrase | 0.0133 | 0.0343 | 0.0343 |
Schistosoma mansoni | cpg binding protein | 0.001 | 0.0018 | 0.0017 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0008 | 0.0014 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0003 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0009 | 0.0017 | 0.0017 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0003 | 0.0002 | 0.0002 |
Onchocerca volvulus | 0.0028 | 0.0068 | 1 | |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0034 | 0.0083 | 0.3389 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0017 | 0.0038 | 0.1638 |
Onchocerca volvulus | 0.0011 | 0.0021 | 0.2906 | |
Echinococcus granulosus | single minded 2 | 0.0011 | 0.0022 | 0.0022 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.0343 | 0.0341 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0034 | 0.0083 | 0.3389 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0038 | 0.0047 |
Echinococcus multilocularis | lamin | 0.0011 | 0.0021 | 0.0021 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0017 | 0.0038 | 0.1638 |
Schistosoma mansoni | carbonic anhydrase | 0.0133 | 0.0343 | 0.0341 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0034 | 0.0083 | 0.0092 |
Loa Loa (eye worm) | DNA topoisomerase I | 0.3795 | 1 | 1 |
Entamoeba histolytica | inositol polyphosphate 5-phosphatase, putative | 0.0017 | 0.0038 | 0.1192 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0022 | 0.005 | 0.005 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0025 | 0.0058 | 0.0044 |
Echinococcus granulosus | intermediate filament protein | 0.0011 | 0.0021 | 0.0021 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0003 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | cytochrome P450 | 0.0034 | 0.0083 | 0.0083 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0003 | 0.0002 | 0.0002 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0003 | 0.0002 | 0.0002 |
Echinococcus granulosus | neutral sphingomyelinase | 0.0017 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | CYP4Cod1 | 0.005 | 0.0124 | 0.0124 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0085 | 0.0217 | 1 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0024 |
Plasmodium falciparum | carbonic anhydrase | 0.0133 | 0.0343 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0.0002 | 0.0002 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0043 | 0.0107 | 0.0107 |
Brugia malayi | intermediate filament protein | 0.0011 | 0.0021 | 0.0021 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0085 | 0.0217 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0003 | 0.0002 | 0.0002 |
Schistosoma mansoni | lamin | 0.0011 | 0.0021 | 0.0019 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0077 | 0.0195 | 0.0195 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0003 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0023 | 0.0054 | 0.1994 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0006 | 0.0006 |
Echinococcus granulosus | lamin dm0 | 0.0011 | 0.0021 | 0.0021 |
Trypanosoma brucei | inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative | 0.0017 | 0.0038 | 0.0032 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0003 | 0.0002 | 0.0002 |
Echinococcus granulosus | carbonic anhydrase | 0.0133 | 0.0343 | 0.0343 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0333 | 0.0871 | 0.116 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0024 |
Brugia malayi | ecdysteroid receptor | 0.0003 | 0.0002 | 0.0002 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0003 | 0.0002 | 0.0002 |
Plasmodium vivax | endonuclease/exonuclease/phosphatase domain containing protein | 0.0017 | 0.0038 | 0.0024 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0003 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0034 | 0.0083 | 0.3389 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0083 | 0.0081 |
Brugia malayi | CCR4 | 0.0017 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.005 | 0.0124 | 0.0124 |
Treponema pallidum | hypothetical protein | 0.0017 | 0.0038 | 0.1192 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0003 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0034 | 0.0083 | 0.3389 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0333 | 0.0871 | 0.0871 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0028 | 0.0068 | 0.0068 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0003 | 0.0002 | 0.0002 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0248 | 0.0648 | 0.0646 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0085 | 0.0217 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0.0002 | 0.0002 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.1192 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0004 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0017 | 0.0038 | 0.5496 | |
Echinococcus granulosus | CCR4 NOT transcription complex subunit 6 | 0.0017 | 0.0038 | 0.0038 |
Schistosoma mansoni | DNA topoisomerase type I | 0.2841 | 0.7485 | 0.7485 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0008 | 0.0014 | 0.0015 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0038 |
Echinococcus granulosus | DNA topoisomerase 1 | 0.3795 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0023 | 0.0054 | 0.1994 |
Mycobacterium leprae | conserved hypothetical protein | 0.0008 | 0.0014 | 0.1359 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0034 | 0.0083 | 0.3389 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0333 | 0.0871 | 0.1147 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0034 | 0.0083 | 0.3389 |
Schistosoma mansoni | ap endonuclease | 0.0085 | 0.0217 | 0.0216 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0017 | 0.0038 | 0.0047 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.002 | 0.0044 | 0.0042 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0024 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0015 | 0.0032 | 0.003 |
Brugia malayi | cytochrome P450 | 0.0034 | 0.0083 | 0.0083 |
Schistosoma mansoni | DNA topoisomerase type I | 0.2841 | 0.7485 | 0.7485 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0003 | 0.0002 | 0.0002 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0.0002 | 0.0002 |
Brugia malayi | Cytochrome P450 family protein | 0.0079 | 0.02 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0034 | 0.0083 | 0.3389 |
Brugia malayi | follicle stimulating hormone receptor | 0.0077 | 0.0195 | 0.0195 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0038 |
Trypanosoma brucei | cytochrome P450, putative | 0.005 | 0.0124 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0343 | 0.0343 |
Echinococcus multilocularis | cpg binding protein | 0.001 | 0.0018 | 0.0018 |
Plasmodium vivax | exodeoxyribonuclease III, putative | 0.0017 | 0.0038 | 0.0024 |
Loa Loa (eye worm) | intermediate filament protein | 0.0011 | 0.0021 | 0.0021 |
Onchocerca volvulus | 0.0017 | 0.0038 | 0.5496 | |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0038 | 0.0047 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0085 | 0.0217 | 0.0217 |
Mycobacterium ulcerans | putative regulatory protein | 0.0011 | 0.0022 | 0.0397 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.005 | 0.0124 | 0.5398 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0085 | 0.0217 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0017 | 0.0038 | 0.0024 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0133 | 0.0343 | 0.0343 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0034 | 0.0083 | 0.3389 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0248 | 0.0648 | 0.0648 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0038 | 0.0038 |
Onchocerca volvulus | 0.0011 | 0.0022 | 0.3036 | |
Plasmodium falciparum | DNase I-like protein, putative | 0.0017 | 0.0038 | 0.0024 |
Onchocerca volvulus | 0.0004 | 0.0003 | 0.0159 | |
Echinococcus multilocularis | transfer RNA-Lys | 0.0011 | 0.0022 | 0.0022 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0003 | 0.0002 | 0.0002 |
Trypanosoma cruzi | DNA topoisomerase type IB small subunit, putative | 0.0954 | 0.2507 | 0.3347 |
Leishmania major | pantothenate kinase subunit, putative | 0.0017 | 0.0038 | 0.0047 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0017 | 0.0038 | 0.1638 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0017 | 0.0038 | 0.0038 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0133 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0068 | 0.0067 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0025 | 0.0058 | 0.2171 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0085 | 0.0217 | 0.0204 |
Echinococcus multilocularis | inositol polyphosphate 5 phosphatase OCRL 1 | 0.0017 | 0.0038 | 0.0038 |
Schistosoma mansoni | cpg binding protein | 0.0009 | 0.0017 | 0.0015 |
Echinococcus granulosus | carbonic anhydrase | 0.0133 | 0.0343 | 0.0343 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0034 | 0.0083 | 0.0107 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0133 | 0.0343 | 0.0343 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0005 | 0.0006 | 0.0006 |
Plasmodium falciparum | topoisomerase I | 0.3795 | 1 | 1 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0004 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0003 | 0.0002 | 0.0002 |
Plasmodium vivax | endonuclease/exonuclease/phosphatase domain containing protein | 0.0017 | 0.0038 | 0.0024 |
Brugia malayi | Cytochrome P450 family protein | 0.005 | 0.0124 | 0.0124 |
Schistosoma mansoni | DNA topoisomerase type I | 0.3795 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0003 | 0.0002 | 0.0002 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0248 | 0.0648 | 0.0648 |
Brugia malayi | hypothetical protein | 0.005 | 0.0125 | 0.0125 |
Trypanosoma brucei | DNA topoisomerase IB, large subunit | 0.2841 | 0.7485 | 1 |
Leishmania major | DNA topoisomerase type IB small subunit | 0.0954 | 0.2507 | 0.3347 |
Trypanosoma brucei | Endonuclease/Exonuclease/phosphatase family, putative | 0.0017 | 0.0038 | 0.0032 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0003 | 0.0002 | 0.0002 |
Schistosoma mansoni | synaptojanin | 0.0017 | 0.0038 | 0.0036 |
Trypanosoma cruzi | DNA topoisomerase IB, large subunit, putative | 0.2841 | 0.7485 | 1 |
Echinococcus granulosus | carbonic anhydrase II | 0.0333 | 0.0871 | 0.0871 |
Schistosoma mansoni | ap endonuclease | 0.0085 | 0.0217 | 0.0216 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0034 | 0.0083 | 0.3389 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0133 | 0.0343 | 0.0343 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0034 | 0.0083 | 0.3389 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0034 | 0.0083 | 0.3389 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0133 | 0.0343 | 0.0341 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0017 | 0.0038 | 0.0047 |
Toxoplasma gondii | DNA topoisomerase I, putative | 0.3795 | 1 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0034 | 0.0083 | 0.3389 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0085 | 0.0217 | 0.0204 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.1192 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0023 | 0.0054 | 0.1994 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0085 | 0.0217 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0003 | 0.0002 | 0.0002 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0085 | 0.0217 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0047 | 0.0116 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.002 | 0.002 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0034 | 0.0083 | 0.3389 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0017 | 0.0038 | 0.0047 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0023 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0.0002 | 0.0002 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0034 | 0.0083 | 0.0069 |
Echinococcus multilocularis | neutral sphingomyelinase | 0.0017 | 0.0038 | 0.0038 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0034 | 0.0083 | 0.3389 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0004 | 0.0003 | 0.0003 |
Trichomonas vaginalis | skeletal muscle/kidney enriched inositol 5-phosphatase, putative | 0.0017 | 0.0038 | 0.1638 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0025 | 0.0058 | 0.0058 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0034 | 0.0083 | 0.3389 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0025 | 0.0058 | 0.0058 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.1192 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0017 | 0.0038 | 0.0038 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase domain containing protein | 0.0017 | 0.0038 | 0.1192 |
Schistosoma mansoni | synaptojanin | 0.0017 | 0.0038 | 0.0036 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0003 | 0.0002 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.0132 | 0.034 | 0.0338 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0033 | 0.0033 |
Brugia malayi | bHLH-PAS transcription factor | 0.0011 | 0.0022 | 0.0022 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0043 | 0.0107 | 0.0107 |
Trypanosoma cruzi | RNA-editing complex protein MP100, putative | 0.0017 | 0.0038 | 0.0047 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0017 | 0.0038 | 0.0038 |
Trichomonas vaginalis | Phospholipase C precursor, putative | 0.0017 | 0.0038 | 0.1638 |
Echinococcus granulosus | lamin | 0.0011 | 0.0021 | 0.0021 |
Schistosoma mansoni | carbon catabolite repressor protein | 0.0017 | 0.0038 | 0.0036 |
Brugia malayi | PAS domain containing protein | 0.0015 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0343 | 0.0343 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0034 | 0.0083 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0125 | 0.0125 |
Brugia malayi | steroid hormone receptor | 0.0003 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0085 | 0.0217 | 0.0217 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0034 | 0.0083 | 0.3389 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0034 | 0.0083 | 0.3389 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0034 | 0.0083 | 0.0107 |
Leishmania major | cytochrome p450-like protein | 0.005 | 0.0124 | 0.0161 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0017 | 0.0038 | 0.0038 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0017 | 0.0038 | 0.0047 |
Echinococcus multilocularis | deoxyribonuclease 1 2 | 0.0017 | 0.0038 | 0.0038 |
Schistosoma mansoni | ocrl type II inositol 5-phosphatase | 0.0017 | 0.0038 | 0.0036 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0003 | 0.0002 | 0.0002 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase domain containing protein | 0.0017 | 0.0038 | 0.1192 |
Trypanosoma brucei | DNA topoisomerase type IB small subunit | 0.0954 | 0.2507 | 0.3337 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0003 | 0.0002 | 0.0002 |
Leishmania major | carbonic anhydrase-like protein | 0.0333 | 0.0871 | 0.116 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0046 | 0.0115 | 0.0115 |
Loa Loa (eye worm) | CCR4-NOT transcription complex subunit 6 family protein | 0.0017 | 0.0038 | 0.0038 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0024 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0006 | 0.0008 | 0.0008 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0133 | 0.0343 | 0.0341 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0085 | 0.0217 | 0.0217 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0003 | 0.0002 | 0.0002 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0333 | 0.0871 | 0.0869 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0021 | 0.0021 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0034 | 0.0083 | 0.3389 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0003 | 0.0002 | 0.0002 |
Onchocerca volvulus | 0.0011 | 0.0021 | 0.2906 | |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0006 | 0.0006 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0003 | 0.0002 | 0.0002 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.1192 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0343 | 0.0343 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0034 | 0.0083 | 0.3389 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0024 |
Trichomonas vaginalis | sphingomyelinase C 2 precursor, putative | 0.0017 | 0.0038 | 0.1638 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0038 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0133 | 0.0343 | 0.0343 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0003 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0025 | 0.0058 | 0.2171 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0085 | 0.0217 | 0.0287 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0003 | 0.0002 | 0.0002 |
Mycobacterium leprae | putative cytochrome p450 | 0.0034 | 0.0083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0.0002 | 0.0002 |
Brugia malayi | hypoxia-induced factor 1 | 0.0046 | 0.0115 | 0.0115 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0024 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0023 | 0.0054 | 0.0053 |
Trypanosoma brucei | inositol/phosphatidylinositol phosphatase, putative | 0.0017 | 0.0038 | 0.0032 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.1192 |
Brugia malayi | CXXC zinc finger family protein | 0.0009 | 0.0017 | 0.0017 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0011 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0003 | 0.0002 | 0.0002 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0018 | 0.0039 | 0.0025 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0034 | 0.0083 | 0.3389 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0133 | 0.0343 | 0.0343 |
Schistosoma mansoni | cript-related | 0.0017 | 0.0038 | 0.0036 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0333 | 0.0871 | 0.0871 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0011 | 0.0021 | 0.0021 |
Echinococcus multilocularis | 0.0034 | 0.0083 | 0.0083 | |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0038 | 0.0036 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0006 | 0.0006 |
Entamoeba histolytica | sphingomyelinase C precursor, putative | 0.0017 | 0.0038 | 0.1192 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0038 | 0.0038 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0003 | 0.0002 | 0.0002 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0003 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0034 | 0.0083 | 0.3389 |
Brugia malayi | Cytochrome P450 family protein | 0.0034 | 0.0083 | 0.0083 |
Trypanosoma brucei | DNA-(apurinic or apyrimidinic site) lyase, putative | 0.0017 | 0.0038 | 0.0032 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0038 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0085 | 0.0217 | 0.0273 |
Leishmania major | cytochrome p450-like protein | 0.0034 | 0.0083 | 0.0107 |
Trypanosoma cruzi | Inositol phosphosphingolipids phospholipase C | 0.0017 | 0.0038 | 0.0047 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0034 | 0.0083 | 0.3389 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0034 | 0.0083 | 0.3389 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0333 | 0.0871 | 0.0869 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0017 | 0.0038 | 0.0024 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0006 | 0.0008 | 0.0008 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0003 | 0.0002 | 0.0002 |
Trichomonas vaginalis | type IV inositol 5-phosphatase, putative | 0.0017 | 0.0038 | 0.1638 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0003 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0017 | 0.0038 | 0.0038 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.1192 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0017 | 0.0038 | 0.0038 |
Schistosoma mansoni | single-minded | 0.0015 | 0.0032 | 0.003 |
Echinococcus granulosus | traf and tnf receptor associated protein | 0.0017 | 0.0038 | 0.0038 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0025 | 0.0058 | 0.0056 |
Schistosoma mansoni | cpg binding protein | 0.001 | 0.0018 | 0.0017 |
Echinococcus granulosus | cpg binding protein | 0.001 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0003 | 0.0002 | 0.0002 |
Echinococcus multilocularis | traf and tnf receptor associated protein | 0.0017 | 0.0038 | 0.0038 |
Echinococcus multilocularis | DNA topoisomerase 1 | 0.3795 | 1 | 1 |
Plasmodium vivax | topoisomerase I, putative | 0.3795 | 1 | 1 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0017 | 0.0038 | 0.0038 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0034 | 0.0083 | 0.3389 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0034 | 0.0083 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0003 | 0.0002 | 0.0002 |
Trypanosoma brucei | Endonuclease/Exonuclease/phosphatase family, putative | 0.0017 | 0.0038 | 0.0032 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0004 | 0.0003 | 0.0003 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0047 | 0.0116 | 0.0116 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0017 | 0.0038 | 0.0047 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0085 | 0.0217 | 0.0287 |
Schistosoma mansoni | intermediate filament proteins | 0.0011 | 0.0021 | 0.0019 |
Trichomonas vaginalis | ocrl type II inositol 5-phosphatase, putative | 0.0017 | 0.0038 | 0.1638 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0038 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0003 | 0.0002 | 0.0002 |
Leishmania major | endonuclease/exonuclease protein-like protein | 0.0017 | 0.0038 | 0.0047 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0085 | 0.0217 | 0.0217 |
Trypanosoma cruzi | mitochondrial protein 99, putative | 0.0017 | 0.0038 | 0.0047 |
Leishmania major | RNA-editing complex protein MP100, putative | 0.0017 | 0.0038 | 0.0047 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0028 | 0.0068 | 0.0067 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0023 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.0003 | 0.0003 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0003 | 0.0002 | 0.0002 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0333 | 0.0871 | 0.0871 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0025 | 0.0058 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0.0002 | 0.0002 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0017 | 0.0038 | 0.0047 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0034 | 0.0083 | 0.3389 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0023 | 0.0054 | 0.0054 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0085 | 0.0217 | 0.0287 |
Toxoplasma gondii | exonuclease III APE | 0.0085 | 0.0217 | 0.0204 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0333 | 0.0871 | 0.0871 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0023 | 0.0054 | 0.0069 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0079 | 0.02 | 0.02 |
Brugia malayi | nuclear hormone receptor | 0.0003 | 0.0002 | 0.0002 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0133 | 0.0343 | 0.0341 |
Entamoeba histolytica | inositol polyphosphate-5-phosphatase, putative | 0.0017 | 0.0038 | 0.1192 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0025 | 0.0058 | 0.0074 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0017 | 0.0038 | 0.0038 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0017 | 0.0038 | 0.0047 |
Echinococcus multilocularis | CCR4 NOT transcription complex subunit 6 | 0.0017 | 0.0038 | 0.0038 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0034 | 0.0083 | 0.3389 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0034 | 0.0083 | 0.3389 |
Trypanosoma cruzi | cytochrome P450, putative | 0.005 | 0.0124 | 0.0161 |
Leishmania major | cytochrome p450-like protein | 0.0034 | 0.0083 | 0.0107 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0132 | 0.034 | 0.0339 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0028 | 0.0068 | 0.0067 |
Schistosoma mansoni | lamin | 0.0011 | 0.0021 | 0.0019 |
Brugia malayi | nuclear receptor NHR-88 | 0.0003 | 0.0002 | 0.0002 |
Echinococcus granulosus | dnaJ subfamily B | 0.0132 | 0.034 | 0.0339 |
Trypanosoma cruzi | mitochondrial protein 99, putative | 0.0017 | 0.0038 | 0.0047 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0017 | 0.0038 | 0.0024 |
Echinococcus multilocularis | carbonic anhydrase | 0.0133 | 0.0343 | 0.0343 |
Echinococcus granulosus | synaptojanin 1 | 0.0017 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0003 | 0.0002 | 0.0002 |
Echinococcus granulosus | inositol polyphosphate 5 phosphatase OCRL 1 | 0.0017 | 0.0038 | 0.0038 |
Toxoplasma gondii | hypothetical protein | 0.0133 | 0.0343 | 0.0329 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0085 | 0.0217 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0034 | 0.0083 | 0.3389 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0034 | 0.0083 | 0.3389 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0034 | 0.0083 | 0.3389 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0003 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0034 | 0.0083 | 0.3389 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0017 | 0.0038 | 0.0047 |
Echinococcus multilocularis | synaptojanin 1 | 0.0017 | 0.0038 | 0.0038 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.