Detailed information for compound 1588055

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 243.239 | Formula: C11H18NO3P
  • H donors: 1 H acceptors: 1 LogP: 2.23 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CCOP(=O)(Oc1ccccc1)N)C
  • InChi: 1S/C11H18NO3P/c1-10(2)8-9-14-16(12,13)15-11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3,(H2,12,13)
  • InChiKey: WQCLBCNYMYAURS-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0048 0.0203 0.0782
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0019 0.0016
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0213 0.0272
Toxoplasma gondii replication factor-a protein 1 (rpa1) subfamily protein 0.047 0.2769 1
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0069 0.02
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0044 0.006
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0022 0.0027
Entamoeba histolytica serine/threonine protein phosphatase PP1, putative 0.0025 0.0059 0.0198
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Mycobacterium ulcerans leucyl-tRNA synthetase 0.0052 0.0226 1
Plasmodium vivax importin-beta 2, putative 0.003 0.0092 0.0284
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0149 0.0893
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0255 0.0246
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0039 0.0088
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0023 0.0032
Plasmodium vivax hypothetical protein, conserved 0.0052 0.0226 0.0769
Leishmania major GTP-binding protein, putative 0.0022 0.0044 0.0107
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0019 0.0016
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0203 0.0258
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.0048 0.0203 0.1272
Trypanosoma cruzi methionyl-tRNA synthetase, putative 0.0052 0.0226 0.0769
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0023 0.017
Leishmania major leucyl-tRNA synthetase, putative 0.0052 0.0226 0.0769
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Loa Loa (eye worm) hypothetical protein 0.0052 0.0226 0.0368
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0044 0.0107
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0048 0.0203 0.0329
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0048 0.0203 0.0277
Leishmania major serine/threonine protein phosphatase catalytic subunit, putative 0.004 0.015 0.0494
Loa Loa (eye worm) methionyl-tRNA synthetase 0.0052 0.0226 0.0368
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0038 0.0032
Brugia malayi protein ZK524.3 0.0052 0.0226 0.0364
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 alpha 0.0025 0.0059 0.0161
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0025 0.0059 0.0083
Schistosoma mansoni protein phosphatase type 1 0.004 0.015 0.0186
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0981 0.5877 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0019 0.0006
Trypanosoma cruzi Replication factor A protein 1 0.047 0.2769 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Brugia malayi CXXC zinc finger family protein 0.0086 0.0429 0.071
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0213 0.038
Plasmodium vivax hypothetical protein, conserved 0.004 0.0149 0.0488
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Onchocerca volvulus 0.004 0.0149 0.0257
Echinococcus granulosus protein phosphatase 1 catalytic subunit 0.004 0.015 0.0205
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0048 0.0203 0.0277
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Trichomonas vaginalis esterase, putative 0.004 0.0149 0.0237
Schistosoma mansoni hypothetical protein 0.014 0.0759 0.1019
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Plasmodium falciparum asparagine--tRNA ligase 0.0048 0.0203 0.0684
Treponema pallidum asparaginyl-tRNA synthetase 0.0048 0.0203 0.0956
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0203 0.886
Echinococcus multilocularis glycyl tRNA synthetase 0.0255 0.1458 0.1449
Trichomonas vaginalis protein phosphatase, caeel, putative 0.0025 0.0059 0.0083
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0149 0.0237
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0023 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0025 0.0059 0.0083
Treponema pallidum methionyl-tRNA synthetase 0.0328 0.1903 1
Entamoeba histolytica hypothetical protein 0.0025 0.006 0.0202
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.014 0.0759 0.075
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0232 0.1322 0.2233
Echinococcus multilocularis geminin 0.0164 0.0904 0.0895
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1322 0.1789
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0213 0.0203
Trichomonas vaginalis bsu-protein phosphatase, putative 0.004 0.015 0.0239
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0019 0.0035
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0019 0.0016
Schistosoma mansoni protein phosphatase-1 0.004 0.015 0.0186
Echinococcus granulosus dna polymerase eta 0.0019 0.0022 0.003
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0022 0.0048
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0328 0.1903 0.768
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0025 0.0059 0.0083
Echinococcus multilocularis protein phosphatase 1 catalytic subunit 0.004 0.015 0.014
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0149 0.0237
Echinococcus granulosus methionine tRNA synthetase 0.0052 0.0226 0.0309
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0023 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Brugia malayi Elongation factor 1 gamma, conserved domain containing protein 0.0017 0.0014 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0038 0.0051
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0048 0.0203 0.0193
Trichomonas vaginalis protein phosphatase, caeel, putative 0.004 0.015 0.0239
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0149 0.0893
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0019 0.0016
Schistosoma mansoni leucyl-tRNA synthetase 0.0052 0.0226 0.029
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.0328 0.1903 0.2599
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0026 0.0028
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0237
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0092 0.0284
Giardia lamblia Aspartyl-tRNA synthetase 0.0048 0.0203 0.25
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0022 0.0016
Plasmodium falciparum importin beta, putative 0.003 0.0092 0.0284
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0019 0.0009
Loa Loa (eye worm) beta-lactamase 0.004 0.0149 0.0237
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-gamma catalytic subunit 0.0025 0.0059 0.0083
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0019 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0026 0.0028
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0149 0.0893
Brugia malayi putative serine/threonine phosphatase 0.0025 0.0059 0.0079
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0237
Toxoplasma gondii aspartate-tRNA ligase 0.0048 0.0203 0.0684
Schistosoma mansoni protein phosphatase-1 0.0025 0.0059 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.0048 0.0203 0.6985
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0203 0.886
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0023 0.0032
Echinococcus multilocularis snurportin 1 0.0323 0.1874 0.1866
Leishmania major hypothetical protein, conserved 0.0026 0.0069 0.02
Entamoeba histolytica replication factor A, putative 0.0095 0.0487 0.1935
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0201 0.1132 0.1124
Trichomonas vaginalis bsu-protein phosphatase, putative 0.004 0.015 0.0239
Brugia malayi RNA, U transporter 1 0.0086 0.0432 0.0715
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0255 0.0349
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0023 0.0032
Schistosoma mansoni hypothetical protein 0.1219 0.7322 1
Schistosoma mansoni apoptosis regulator bax 0.014 0.0759 0.1019
Echinococcus granulosus serine:threonine protein phosphatase PP1 beta 0.004 0.015 0.0205
Entamoeba histolytica hypothetical protein 0.0025 0.0058 0.0194
Leishmania major aspartyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Plasmodium vivax methionine--tRNA ligase, putative 0.0052 0.0226 0.0769
Leishmania major methionyl-tRNA synthetase, putative 0.0052 0.0226 0.0769
Loa Loa (eye worm) histone methyltransferase 0.0026 0.0069 0.0101
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0255 0.0414
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0149 0.6218
Giardia lamblia Hypothetical protein 0.0144 0.0781 1
Leishmania major DNA polymerase eta, putative 0.0019 0.0022 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Toxoplasma gondii ABC1 family protein 0.004 0.0149 0.0488
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0019 0.0011
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0069 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.0048 0.0203 0.0329
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0237
Schistosoma mansoni cpg binding protein 0.009 0.0459 0.0608
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Echinococcus granulosus lysyl tRNA synthetase 0.0048 0.0203 0.0277
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0049
Loa Loa (eye worm) hypothetical protein 0.0057 0.0255 0.0418
Treponema pallidum leucyl-tRNA synthetase 0.0052 0.0226 0.108
Trichomonas vaginalis methionine-tRNA synthetase, putative 0.0052 0.0226 0.0368
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0255 0.033
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0255 0.0246
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0092 0.0284
Echinococcus multilocularis serine:threonine protein phosphatase PP1 isozyme 0.004 0.015 0.014
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.004 0.015 0.014
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0022 0.002
Schistosoma mansoni hypothetical protein 0.0048 0.0203 0.0258
Leishmania major DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Trichomonas vaginalis ran, putative 0.0022 0.0044 0.0058
Onchocerca volvulus 0.005 0.0213 0.038
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0019 0.0017
Brugia malayi Serine/threonine protein phosphatase PP1-beta catalytic subunit 0.004 0.015 0.0235
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0893
Loa Loa (eye worm) hypothetical protein 0.005 0.0213 0.0346
Mycobacterium tuberculosis Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) 0.0052 0.0226 0.1436
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Trichomonas vaginalis protein phosphatase-1, putative 0.0025 0.0059 0.0083
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0149 0.0488
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.004 0.015 0.014
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0255 0.1458 0.2468
Toxoplasma gondii exonuclease III APE 0.0019 0.0023 0.0032
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0048 0.0203 0.0193
Schistosoma mansoni DNA polymerase eta 0.0019 0.0022 0.001
Plasmodium vivax serine/threonine protein phosphatase PP1, putative 0.004 0.015 0.0494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Brugia malayi mbt repeat family protein 0.005 0.0213 0.0342
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0149 0.0184
Giardia lamblia Ser/Thr protein phosphatase PP1-alpha 2 catalytic subunit 0.004 0.015 0.1819
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0026 0.0028
Wolbachia endosymbiont of Brugia malayi leucyl-tRNA synthetase 0.0052 0.0226 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Brugia malayi lysyl-tRNA synthetase 0.0048 0.0203 0.0325
Schistosoma mansoni hypothetical protein 0.0164 0.0904 0.1218
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0023 0.0062
Plasmodium vivax replication protein A1, large subunit, putative 0.047 0.2769 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0162 0.0895 0.3195
Entamoeba histolytica hypothetical protein 0.0048 0.0203 0.0782
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0023 0.0032
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0022 0.0027
Toxoplasma gondii OB-fold nucleic acid binding domain-containing protein 0.0247 0.1408 0.5059
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0213 0.0272
Schistosoma mansoni protein phosphatase type 1 0.004 0.015 0.0186
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0019 0.0016
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.006 0.0081
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0022 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Echinococcus granulosus importin subunit beta 1 0.003 0.0092 0.0126
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.014 0.0759 0.1273
Echinococcus granulosus cpg binding protein 0.009 0.0459 0.0626
Schistosoma mansoni protein phosphatase-1 0.004 0.015 0.0186
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0026 0.0028
Mycobacterium ulcerans lipase LipD 0.004 0.0149 0.6218
Schistosoma mansoni hypothetical protein 0.0308 0.1784 0.2422
Brugia malayi methionyl-tRNA synthetase 0.0052 0.0226 0.0364
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0095 0.0487 0.0903
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0023 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Entamoeba histolytica Ran family GTPase 0.0022 0.0044 0.0138
Schistosoma mansoni importin beta-1 0.003 0.0092 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0022 0.002
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0044 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0203 0.0258
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0933 0.5583 0.9498
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0149 0.0488
Leishmania major aspartyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Toxoplasma gondii tRNA ligases class I (M) protein 0.0052 0.0226 0.0769
Treponema pallidum aspartyl-tRNA synthetase 0.0048 0.0203 0.0956
Toxoplasma gondii methionyl-tRNA synthetase 0.0052 0.0226 0.0769
Leishmania major lysyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0893
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0092 0.0284
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0021 0.0038 0.0028
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0048 0.0203 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0023 0.0018
Chlamydia trachomatis leucine--tRNA ligase 0.0052 0.0226 0.0137
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0253 0.1444 1
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0149 0.0893
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0023 0.0414
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-beta catalytic subunit 0.004 0.015 0.0239
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0149 0.0139
Echinococcus multilocularis importin subunit beta 1 0.003 0.0092 0.0083
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0213 0.0346
Schistosoma mansoni aspartyl-tRNA synthetase 0.0048 0.0203 0.0258
Giardia lamblia Lysyl-tRNA synthetase 0.0048 0.0203 0.25
Schistosoma mansoni ran 0.0022 0.0044 0.0041
Loa Loa (eye worm) apoptosis regulator protein 0.014 0.0759 0.1277
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0213 0.0291
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0019 0.0006
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0255 0.1458 0.2468
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Schistosoma mansoni aspartyl-tRNA synthetase 0.0048 0.0203 0.0258
Schistosoma mansoni protein phosphatase type 1 0.0025 0.0059 0.0061
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.006 0.0062
Schistosoma mansoni aspartyl-tRNA synthetase 0.0048 0.0203 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0026 0.0028
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.004 0.015 0.0239
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0981 0.5877 0.8027
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0058 0.0081
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0149 0.0893
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1322 0.1789
Giardia lamblia Leucyl-tRNA synthetase 0.0052 0.0226 0.2801
Echinococcus granulosus dnaJ subfamily B 0.1219 0.7322 1
Leishmania major asparaginyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0213 0.0203
Trichomonas vaginalis bsu-protein phosphatase, putative 0.004 0.015 0.0239
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0149 0.0893
Loa Loa (eye worm) 63kd antigen 0.0048 0.0203 0.0329
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0023 0.0022
Echinococcus granulosus geminin 0.0164 0.0904 0.1235
Schistosoma mansoni ap endonuclease 0.0019 0.0023 0.0012
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0022 0.0027
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0019 0.0035
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.047 0.2769 0.4703
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0203 0.0684
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Echinococcus granulosus protein phosphatase 1, catalytic subunit, beta isozyme 0.004 0.015 0.0205
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Brugia malayi methionyl-tRNA synthetase 0.0328 0.1903 0.3224
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.014 0.0759 0.1019
Schistosoma mansoni methionine-tRNA synthetase 0.0328 0.1903 0.2585
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0878 0.525 1
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Trypanosoma brucei protein phosphatase 1 0.0025 0.0059 0.0161
Toxoplasma gondii lysine-tRNA ligase 0.0048 0.0203 0.0684
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0044 0.0107
Leishmania major hypothetical protein, conserved 0.004 0.0149 0.0488
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0023 0.0032
Loa Loa (eye worm) MBCTL1 0.0057 0.0255 0.0418
Echinococcus multilocularis leucyl tRNA synthetase 0.0052 0.0226 0.0216
Trypanosoma brucei unspecified product 0.0019 0.0022 0.0027
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.002
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.006 0.0165
Brugia malayi Serine/threonine protein phosphatase PP1 isozyme 1, putative 0.0025 0.0059 0.0079
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0255 0.0349
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0019 0.0016
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0067 0.0094
Mycobacterium tuberculosis Conserved protein 0.004 0.0149 0.0893
Plasmodium falciparum replication protein A1, large subunit 0.047 0.2769 1
Schistosoma mansoni aspartyl-tRNA synthetase 0.0048 0.0203 0.0258
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0044 0.0054
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.014 0.0759 0.1037
Schistosoma mansoni glycyl-tRNA synthetase 0.0255 0.1458 0.1975
Giardia lamblia Methionyl-tRNA synthetase 0.0052 0.0226 0.2801
Echinococcus granulosus protein phosphatase 1 catalytic subunit 0.0017 0.001 0.0014
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0201 0.1132 0.1547
Loa Loa (eye worm) hypothetical protein 0.014 0.0759 0.1277
Brugia malayi replication factor A 73 kDa subunit 0.0981 0.5877 1
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0019 0.0016
Brugia malayi hypothetical protein 0.0026 0.0069 0.0097
Schistosoma mansoni aspartyl-tRNA synthetase 0.0048 0.0203 0.0258
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0182 0.1012 0.1366
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.006 0.0165
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0149 0.0237
Echinococcus granulosus dna polymerase kappa 0.0019 0.0022 0.003
Onchocerca volvulus 0.004 0.0149 0.0257
Onchocerca volvulus 0.004 0.0149 0.0257
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0044 0.0107
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0069 0.02
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0019 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0026 0.0028
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0149 0.0233
Echinococcus multilocularis cpg binding protein 0.009 0.0459 0.0449
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0019 0.0017
Schistosoma mansoni methionine-tRNA synthetase 0.0052 0.0226 0.029
Brugia malayi Aspartyl-tRNA synthetase 0.0048 0.0203 0.0325
Echinococcus multilocularis lysyl tRNA synthetase 0.0048 0.0203 0.0193
Trypanosoma cruzi replication Factor A 28 kDa subunit, putative 0.0048 0.0203 0.0684
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0981 0.5877 1
Trichomonas vaginalis helicase, putative 0.0019 0.0026 0.0028
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0048 0.0203 0.0329
Loa Loa (eye worm) hypothetical protein 0.004 0.015 0.0239
Loa Loa (eye worm) hypothetical protein 0.0048 0.0203 0.0329
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1322 0.1789
Chlamydia trachomatis methionine--tRNA ligase 0.0328 0.1903 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0237
Trypanosoma brucei serine threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0044 0.0107
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0019 0.0016
Onchocerca volvulus 0.0086 0.0429 0.0792
Schistosoma mansoni ap endonuclease 0.0019 0.0023 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0019 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0058 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0232 0.1322 0.1313
Leishmania major importin beta-1 subunit, putative 0.0025 0.0058 0.0158
Schistosoma mansoni hypothetical protein 0.0164 0.0904 0.1218
Trypanosoma brucei serine threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0058 0.0158
Schistosoma mansoni cpg binding protein 0.009 0.0459 0.0608
Plasmodium vivax aspartate--tRNA ligase, putative 0.0048 0.0203 0.0684
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0019 0.0025
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0149 0.0893
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.0328 0.1903 0.1895
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0981 0.5877 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0022 0.001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0019 0.0016
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0044 0.0034
Leishmania major replication factor A, 51kDa subunit, putative 0.047 0.2769 1
Plasmodium falciparum nucleic acid binding protein, putative 0.0048 0.0203 0.0684
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0052 0.0226 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0026 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0069 0.0095
Loa Loa (eye worm) serine/threonine protein phosphatase PP1 isozyme 1 0.0025 0.0059 0.0083
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0022 0.001
Brugia malayi glycyl-tRNA synthetase 0.0255 0.1458 0.2464
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0026 0.0028
Brugia malayi Glutathione S-transferase, N-terminal domain containing protein 0.0017 0.0014 0.0003
Brugia malayi Serine/threonine protein phosphatase F56C9.1 in chromosomeIII 0.004 0.015 0.0235
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Echinococcus granulosus snurportin 1 0.0323 0.1874 0.2559
Schistosoma mansoni aspartyl-tRNA synthetase 0.0048 0.0203 0.0258
Schistosoma mansoni replication factor A 1 rfa1 0.0981 0.5877 0.8023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0026 0.0028
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0429 0.0714
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0785 0.468 0.4675
Entamoeba histolytica replication factor A protein 1, putative 0.0422 0.2475 1
Schistosoma mansoni ran 0.0022 0.0044 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.0083
Trichomonas vaginalis protein phosphatase-1, putative 0.0025 0.0059 0.0083
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0019 0.0016
Schistosoma mansoni hypothetical protein 0.014 0.0759 0.1019
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0069 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Echinococcus multilocularis eukaryotic translation elongation factor 1 0.0017 0.0014 0.0004
Toxoplasma gondii serine/threonine phosophatase PP1 0.004 0.015 0.0494
Plasmodium falciparum lysine--tRNA ligase 0.0048 0.0203 0.0684
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0023 0.0009
Echinococcus multilocularis methionine tRNA synthetase 0.0052 0.0226 0.0216
Plasmodium vivax asparagine--tRNA ligase, putative 0.0048 0.0203 0.0684
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0785 0.468 0.6392
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0026 0.0028
Plasmodium falciparum methionine--tRNA ligase 0.0052 0.0226 0.0769
Plasmodium vivax lysine--tRNA ligase, putative 0.0048 0.0203 0.0684
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0237
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0981 0.5877 0.5873
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0026 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0026 0.0028
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0069 0.02
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0019 0.0016
Brugia malayi Serine/threonine protein phosphatase PP1-gamma catalytic subunit 0.0025 0.0059 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0213 0.0291
Giardia lamblia GTOR 0.0018 0.0019 0.0113
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0232 0.1322 0.1313
Trypanosoma cruzi serine/threonine protein phosphatase catalytic subunit, putative 0.004 0.015 0.0494
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0232 0.1322 0.1805
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0038 0.0028
Loa Loa (eye worm) serine/threonine protein phosphatase PP1 isozyme 1 0.0025 0.0059 0.0083
Loa Loa (eye worm) hypothetical protein 0.0095 0.0487 0.0813
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0255 0.1458 0.2464
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0237
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0025 0.0059 0.0083
Trypanosoma brucei Replication factor A protein 1 0.047 0.2769 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0069 0.006
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0149 0.6218
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0323 0.1874 0.3177
Brugia malayi beta-lactamase family protein 0.004 0.0149 0.0233
Schistosoma mansoni aspartyl-tRNA synthetase 0.0048 0.0203 0.0258
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0069 0.02
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0022 0.0012
Echinococcus multilocularis glutathione S transferase 0.0017 0.0014 0.0004
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0022 0.0012
Mycobacterium ulcerans beta-lactamase 0.004 0.0149 0.6218
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0014 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0232 0.1322 0.1805
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0026 0.0028
Plasmodium falciparum asparagine--tRNA ligase 0.0048 0.0203 0.0684
Wolbachia endosymbiont of Brugia malayi methionyl-tRNA synthetase 0.0052 0.0226 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Mycobacterium ulcerans aspartyl-tRNA synthetase 0.0048 0.0203 0.886
Schistosoma mansoni cpg binding protein 0.0086 0.0429 0.0567
Schistosoma mansoni hypothetical protein 0.0323 0.1874 0.2545
Trichomonas vaginalis protein phosphatase-1, putative 0.004 0.015 0.0239
Brugia malayi BRCA2 repeat family protein 0.0198 0.1114 0.1878
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0149 0.0237
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.0048 0.0203 0.1272
Toxoplasma gondii hypothetical protein 0.0103 0.0535 0.1891
Schistosoma mansoni aspartyl-tRNA synthetase 0.0048 0.0203 0.0258
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0101
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0044 0.0107
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0048 0.0203 0.0193
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.0048 0.0203 0.0782
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0044 0.0107
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0048 0.0203 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Plasmodium vivax methionine--tRNA ligase, putative 0.0052 0.0226 0.0769
Loa Loa (eye worm) BRCA2 repeat family protein 0.0198 0.1114 0.1882
Trypanosoma brucei protein phosphatase 1 0.0025 0.0059 0.0161
Echinococcus granulosus serine protein kinase ATM 0.0025 0.006 0.0082
Leishmania major lysyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Mycobacterium ulcerans hypothetical protein 0.004 0.0149 0.6218
Echinococcus granulosus mixed lineage leukemia protein mll 0.0021 0.0038 0.0051
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0149 0.0184
Loa Loa (eye worm) hypothetical protein 0.0328 0.1903 0.3227
Trypanosoma brucei serine threonine-protein phosphatase PP1, putative 0.0025 0.0059 0.0161
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0213 0.0272
Mycobacterium leprae Probable methionyl-tRNA synthase MetS 0.0052 0.0226 1
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0025 0.0059 0.0083
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0048 0.0203 0.0684
Trypanosoma brucei methionyl-tRNA synthetase, putative 0.0052 0.0226 0.0769
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0069 0.02
Leishmania major replication Factor A 28 kDa subunit, putative 0.0048 0.0203 0.0684
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0044 0.044
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0019 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.006 0.0085
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0048 0.0203 0.6985
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0007
Schistosoma mansoni protein phosphatase-1 0.0025 0.0059 0.0061
Echinococcus multilocularis dnaJ subfamily B 0.1219 0.7322 0.7319
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0022 0.0027
Trypanosoma brucei protein phosphatase 1, putative 0.004 0.015 0.0494
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0026 0.0028
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0022 0.0027
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0023 0.0031
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0232 0.1322 0.2236
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Brugia malayi beta-lactamase family protein 0.004 0.0149 0.0233
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0023 0.0032
Plasmodium vivax asparagine--tRNA ligase, putative 0.0048 0.0203 0.0684
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0058 0.0081
Echinococcus granulosus stringent starvation protein A 0.0017 0.0014 0.0019
Echinococcus multilocularis serine:threonine protein phosphatase PP1 beta 0.004 0.015 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0023 0.0022
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0022 0.002
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.004 0.015 0.0205
Echinococcus granulosus glutathione S transferase 0.0017 0.0014 0.0019
Giardia lamblia Elongation factor 1-gamma 0.0017 0.0014 0.0056
Mycobacterium ulcerans methionyl-tRNA synthetase 0.0052 0.0226 1
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0149 0.0488
Trichomonas vaginalis protein phosphatase-5, putative 0.0025 0.0059 0.0083
Brugia malayi Importin beta-1 subunit 0.003 0.0092 0.0137
Brugia malayi mbt repeat family protein 0.005 0.0213 0.0342
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0019 0.0015
Giardia lamblia Asparaginyl-tRNA synthetase 0.0048 0.0203 0.25
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0019 0.0015
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0019 0.0016
Plasmodium falciparum serine/threonine protein phosphatase PP1 0.004 0.015 0.0494
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0237
Leishmania major serine/threonine protein phosphatase pp1(5.9), putative 0.0025 0.0059 0.0161
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0019 0.0016
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0276 0.1585 0.2685
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0019 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0026 0.0028
Brugia malayi beta-lactamase 0.004 0.0149 0.0233
Brugia malayi hypothetical protein 0.0017 0.0014 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0026 0.0028
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.0048 0.0203 0.0782
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0048 0.0203 0.0325
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0022 0.003
Brugia malayi Serine/threonine protein phosphatase PP1 isozyme 1, putative 0.0025 0.0059 0.0079
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0149 0.0203
Schistosoma mansoni aspartyl-tRNA synthetase 0.0048 0.0203 0.0258
Echinococcus granulosus glycyl tRNA synthetase 0.0255 0.1458 0.1991
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0022 0.0027
Wolbachia endosymbiont of Brugia malayi aspartyl-tRNA synthetase 0.0048 0.0203 0.89
Plasmodium falciparum aspartate--tRNA ligase 0.0048 0.0203 0.0684
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0141
Plasmodium falciparum methionine--tRNA ligase, putative 0.0052 0.0226 0.0769
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0048 0.0203 0.0684
Schistosoma mansoni hypothetical protein 0.014 0.0759 0.1019
Echinococcus multilocularis dna polymerase eta 0.0019 0.0022 0.0012
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0022 0.0016
Echinococcus granulosus eukaryotic translation elongation factor 1 0.0017 0.0014 0.0019
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.006 0.005
Brugia malayi Serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0025 0.0059 0.0079
Giardia lamblia DINP protein human, muc B family 0.0019 0.0022 0.0154
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.004 0.015 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0015
Toxoplasma gondii FATC domain-containing protein 0.0025 0.006 0.0165

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 2.0787 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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