Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | carboxylesterase 5A | 0.5339 | 0.8742 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0902 | 0.0569 | 0.0562 |
Echinococcus granulosus | carboxylesterase 5A | 0.5339 | 0.8742 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.5339 | 0.8742 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0902 | 0.0569 | 0.0459 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0767 | 0.0319 | 0.0365 |
Loa Loa (eye worm) | hypothetical protein | 0.0902 | 0.0569 | 0.0459 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0902 | 0.0569 | 0.0651 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0902 | 0.0569 | 0.0296 |
Onchocerca volvulus | Bile acid receptor homolog | 0.3335 | 0.505 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.5339 | 0.8742 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.5339 | 0.8742 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0902 | 0.0569 | 0.0562 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.5339 | 0.8742 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.5339 | 0.8742 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.5339 | 0.8742 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.5339 | 0.8742 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0902 | 0.0569 | 0.0296 |
Echinococcus multilocularis | acetylcholinesterase | 0.5339 | 0.8742 | 1 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.5598 | 0.9219 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0902 | 0.0569 | 0.0651 |
Loa Loa (eye worm) | carboxylesterase | 0.5339 | 0.8742 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1282 | 0.1269 | 0.1276 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0902 | 0.0569 | 0.0651 |
Loa Loa (eye worm) | carboxylesterase | 0.0902 | 0.0569 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.0902 | 0.0569 | 0.0459 |
Schistosoma mansoni | gliotactin | 0.0902 | 0.0569 | 0.0651 |
Loa Loa (eye worm) | hypothetical protein | 0.0902 | 0.0569 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.0902 | 0.0569 | 0.0459 |
Brugia malayi | Carboxylesterase family protein | 0.5339 | 0.8742 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0902 | 0.0569 | 0.0459 |
Echinococcus granulosus | neuroligin | 0.0902 | 0.0569 | 0.0296 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.5339 | 0.8742 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.6022 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0902 | 0.0569 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0902 | 0.0569 | 0.0651 |
Loa Loa (eye worm) | carboxylesterase | 0.0902 | 0.0569 | 0.0459 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0902 | 0.0569 | 0.0296 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0902 | 0.0569 | 0.5 |
Echinococcus multilocularis | neuroligin | 0.0902 | 0.0569 | 0.0562 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0902 | 0.0569 | 0.0562 |
Loa Loa (eye worm) | hypothetical protein | 0.3335 | 0.505 | 0.569 |
Loa Loa (eye worm) | hypothetical protein | 0.0902 | 0.0569 | 0.0459 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.1627 | 0.1904 | 0.1634 |
Schistosoma mansoni | acetylcholinesterase | 0.0902 | 0.0569 | 0.0651 |
Brugia malayi | ecdysteroid receptor | 0.3335 | 0.505 | 0.5482 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0902 | 0.0569 | 0.0651 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.