Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.8573 | 0.8573 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0074 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.005 | 0.3394 | 0.3394 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.005 | 0.3394 | 0.3182 |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.8573 | 0.8527 |
Leishmania major | cysteine peptidase A (CPA) | 0.0074 | 1 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0038 | 0.0311 | 0.0311 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0074 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0074 | 1 | 1 |
Onchocerca volvulus | 0.0074 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0074 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.005 | 0.3394 | 0.3394 |
Plasmodium vivax | vivapain-2 | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0074 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0038 | 0.0311 | 0.0311 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.8573 | 0.8573 |
Brugia malayi | Cathepsin L-like precursor | 0.0074 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.8573 | 0.8573 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.005 | 0.3394 | 0.3182 |
Loa Loa (eye worm) | cysteine protease | 0.0074 | 1 | 1 |
Onchocerca volvulus | 0.0074 | 1 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0074 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0074 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.462 | 0.462 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.3394 | 0.3394 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0038 | 0.0311 | 0.0311 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0074 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0074 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0074 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0074 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0074 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.8573 | 0.8573 |
Onchocerca volvulus | 0.0074 | 1 | 1 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.8573 | 0.8573 |
Onchocerca volvulus | 0.0074 | 1 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.005 | 0.3394 | 0.3394 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0074 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0074 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0038 | 0.0311 | 0.0311 |
Leishmania major | cathepsin L-like protease | 0.0074 | 1 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0074 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.462 | 0.462 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0074 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0074 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.005 | 0.3394 | 0.3394 |
Onchocerca volvulus | 0.0074 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0074 | 1 | 0.5 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0074 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.8573 | 0.8573 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0074 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0069 | 0.8573 | 0.8573 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0074 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0074 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.8573 | 0.8573 |
Leishmania major | cathepsin L-like protease | 0.0074 | 1 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.8573 | 0.8573 |
Echinococcus multilocularis | cysteine protease | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0074 | 1 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.3394 | 0.3394 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0074 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.462 | 0.462 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0074 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Onchocerca volvulus | 0.0074 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0038 | 0.0311 | 0.0311 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.8573 | 0.8573 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.005 | 0.3394 | 0.3182 |
Toxoplasma gondii | cathepsin CPL | 0.0074 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.3394 | 0.3394 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.8573 | 0.8573 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0074 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0074 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0074 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.005 | 0.3394 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0074 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.8573 | 0.8527 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.462 | 0.462 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0074 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0074 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0074 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.005 | 0.3394 | 0.3182 |
Onchocerca volvulus | 0.0074 | 1 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0074 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0074 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0074 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.005 | 0.3394 | 0.3394 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.