Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.3058 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0517 | 0.1403 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.3058 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0517 | 0.1403 | 0.0291 |
Onchocerca volvulus | 0.0517 | 0.1403 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0517 | 0.1403 | 0.5 |
Onchocerca volvulus | 0.0517 | 0.1403 | 1 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0517 | 0.1403 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0517 | 0.1403 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0517 | 0.1403 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.3058 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.3058 | 1 | 1 |
Trypanosoma brucei | RNA helicase, putative | 0.0102 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.3058 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0517 | 0.1403 | 0.1403 |
Echinococcus multilocularis | carboxylesterase 5A | 0.3058 | 1 | 1 |
Onchocerca volvulus | 0.0517 | 0.1403 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 0.1403 | 0.0291 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.3058 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0517 | 0.1403 | 0.0291 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0517 | 0.1403 | 0.1403 |
Schistosoma mansoni | acetylcholinesterase | 0.0517 | 0.1403 | 0.1403 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 0.1403 | 0.0291 |
Echinococcus multilocularis | neuroligin | 0.0517 | 0.1403 | 0.0291 |
Onchocerca volvulus | 0.0517 | 0.1403 | 1 | |
Onchocerca volvulus | 0.0517 | 0.1403 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.3058 | 1 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0517 | 0.1403 | 0.1403 |
Loa Loa (eye worm) | carboxylesterase | 0.0517 | 0.1403 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 0.1403 | 0.0291 |
Echinococcus granulosus | carboxylesterase 5A | 0.3058 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0517 | 0.1403 | 0.1403 |
Echinococcus granulosus | neuroligin | 0.0517 | 0.1403 | 0.0291 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0517 | 0.1403 | 0.1403 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0517 | 0.1403 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 0.1403 | 0.0291 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0517 | 0.1403 | 0.0291 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0517 | 0.1403 | 0.1403 |
Loa Loa (eye worm) | carboxylesterase | 0.0517 | 0.1403 | 0.0291 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0441 | 0.1145 | 0.1145 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 0.1403 | 0.0291 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0517 | 0.1403 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 0.1403 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 0.1403 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.3058 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.3058 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0517 | 0.1403 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.3058 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0517 | 0.1403 | 0.0291 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.