Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0055 | 0.0711 | 0.1239 |
Schistosoma mansoni | nuclear receptor | 0.0018 | 0.0152 | 0.0152 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0037 | 0.0438 | 0.0438 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0055 | 0.0711 | 0.1242 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0711 | 0.1239 |
Brugia malayi | ecdysone receptor | 0.0018 | 0.0152 | 0.0232 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0326 | 0.0326 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0178 | 0.2557 | 0.2557 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0018 | 0.0152 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0711 | 0.1239 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0018 | 0.0152 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Brugia malayi | nuclear hormone receptor | 0.0055 | 0.0711 | 0.1242 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0055 | 0.0711 | 0.0711 |
Brugia malayi | ecdysteroid receptor | 0.0377 | 0.5555 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0055 | 0.0711 | 0.1239 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0037 | 0.0438 | 0.0748 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0018 | 0.0152 | 0.0152 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0301 | 0.0301 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0672 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0055 | 0.0711 | 0.0711 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0018 | 0.0152 | 0.0152 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0018 | 0.0152 | 0.0232 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0055 | 0.0711 | 0.1239 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0055 | 0.0711 | 0.1242 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0018 | 0.0152 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0377 | 0.5555 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0055 | 0.0711 | 0.1242 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Schistosoma mansoni | thyroid hormone receptor | 0.0178 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0018 | 0.0152 | 0.0152 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0055 | 0.0711 | 0.0711 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0693 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0055 | 0.0711 | 0.0711 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0438 | 0.0746 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0018 | 0.0152 | 0.0152 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0055 | 0.0711 | 0.1242 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0326 | 0.0326 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0055 | 0.0711 | 0.1242 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0711 | 0.1239 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0438 | 0.0746 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0055 | 0.0711 | 0.0711 |
Onchocerca volvulus | 0.0055 | 0.0711 | 0.1034 | |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0123 | 0.1726 | 0.1726 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.03 | 0.05 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Onchocerca volvulus | 0.0028 | 0.03 | 0.0274 | |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0037 | 0.0438 | 0.0438 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0789 | 0.0789 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.2941 | 0.5273 |
Brugia malayi | nuclear receptor NHR-67 | 0.0018 | 0.0152 | 0.0232 |
Echinococcus granulosus | dnaJ subfamily B | 0.0398 | 0.5878 | 0.5878 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0055 | 0.0711 | 0.0711 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0055 | 0.0711 | 0.0711 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0152 | 0.0232 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0018 | 0.0152 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0711 | 0.1239 |
Brugia malayi | tailless protein | 0.0018 | 0.0152 | 0.0232 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0055 | 0.0711 | 0.1242 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0018 | 0.0152 | 0.0152 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0055 | 0.0711 | 0.1242 |
Brugia malayi | nuclear receptor NHR-88 | 0.0055 | 0.0711 | 0.1242 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0438 | 0.0748 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0055 | 0.0711 | 0.0711 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0055 | 0.0711 | 0.1034 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0123 | 0.1726 | 0.1726 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0018 | 0.0152 | 0.0229 |
Onchocerca volvulus | 0.0231 | 0.3362 | 0.5942 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0055 | 0.0711 | 0.1239 |
Onchocerca volvulus | 0.003 | 0.0326 | 0.0322 | |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0326 | 0.0326 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0055 | 0.0711 | 0.1242 |
Schistosoma mansoni | zinc finger protein | 0.0018 | 0.0152 | 0.0152 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0026 | 0.0026 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0055 | 0.0711 | 0.0711 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0055 | 0.0711 | 0.1242 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0711 | 0.1239 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0055 | 0.0711 | 0.0711 |
Schistosoma mansoni | hypothetical protein | 0.0398 | 0.5878 | 0.5878 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0055 | 0.0711 | 0.0711 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.1726 | 0.1726 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0326 | 0.0546 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0018 | 0.0152 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0711 | 0.1239 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0326 | 0.0326 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0037 | 0.0438 | 0.0438 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0018 | 0.0152 | 0.0152 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0055 | 0.0711 | 0.0711 |
Loa Loa (eye worm) | DR-78 | 0.0018 | 0.0152 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0055 | 0.0711 | 0.0711 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0398 | 0.5878 | 0.5878 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0055 | 0.0711 | 0.1239 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0018 | 0.0152 | 0.0152 |
Schistosoma mansoni | coup transcription factor | 0.0055 | 0.0711 | 0.0711 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0324 | 0.0324 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0055 | 0.0711 | 0.0711 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0018 | 0.0152 | 0.0232 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0152 | 0.0232 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0055 | 0.0711 | 0.0711 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0055 | 0.0711 | 0.1242 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0055 | 0.0711 | 0.1242 |
Schistosoma mansoni | thyroid hormone receptor | 0.0178 | 0.2557 | 0.2557 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0055 | 0.0711 | 0.1242 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0326 | 0.0326 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0324 | 0.0324 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0055 | 0.0711 | 0.1239 |
Schistosoma mansoni | nuclear hormone receptor | 0.0055 | 0.0711 | 0.0711 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.03 | 0.03 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0018 | 0.0152 | 0.0152 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0055 | 0.0711 | 0.1242 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0055 | 0.0711 | 0.1239 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0037 | 0.0438 | 0.0438 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0055 | 0.0711 | 0.0711 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0055 | 0.0711 | 0.1242 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0037 | 0.0438 | 0.0748 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0055 | 0.0711 | 0.0711 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0018 | 0.0152 | 0.0152 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0055 | 0.0711 | 0.1239 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0438 | 0.0746 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0026 | 0.0026 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0018 | 0.0152 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0711 | 0.1239 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0055 | 0.0711 | 0.0711 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0152 | 0.0152 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0326 | 0.5 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0324 | 0.0324 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0152 | 0.0152 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0055 | 0.0711 | 0.0711 |
Brugia malayi | nuclear receptor RXR | 0.0018 | 0.0152 | 0.0232 |
Trichomonas vaginalis | set domain proteins, putative | 0.0231 | 0.3362 | 0.5 |
Brugia malayi | conserved hypotetical protein | 0.0018 | 0.0152 | 0.0232 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0152 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0055 | 0.0711 | 0.0711 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0055 | 0.0711 | 0.1242 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0055 | 0.0711 | 0.1242 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0055 | 0.0711 | 0.0711 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0377 | 0.5555 | 1 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0438 | 0.0748 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0018 | 0.0152 | 0.0232 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0055 | 0.0711 | 0.0711 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0152 | 0.0232 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0018 | 0.0152 | 0.0152 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0037 | 0.0438 | 0.0746 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0055 | 0.0711 | 0.0711 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0152 | 0.0229 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0152 | 0.0232 |
Schistosoma mansoni | nuclear receptor | 0.0018 | 0.0152 | 0.0152 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0324 | 0.0324 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0326 | 0.0326 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0152 | 0.0152 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0055 | 0.0711 | 0.1034 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0438 | 0.0746 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0018 | 0.0152 | 0.0232 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0055 | 0.0711 | 0.0711 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0326 | 0.0326 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0438 | 0.0746 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0018 | 0.0152 | 0.0232 |
Brugia malayi | nuclear receptor RXR | 0.0037 | 0.0438 | 0.0748 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0326 | 0.0544 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.03 | 0.0497 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0672 | 1 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.2941 | 0.5272 |
Brugia malayi | steroid hormone receptor | 0.0055 | 0.0711 | 0.1242 |
Echinococcus granulosus | FTZ F1 alpha | 0.0055 | 0.0711 | 0.0711 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0055 | 0.0711 | 0.0711 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.