Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Metabotropic glutamate receptor homolog | 0.0064 | 0.0343 | 0.1208 |
Loa Loa (eye worm) | glutamate receptor | 0.0154 | 0.0982 | 0.2979 |
Echinococcus granulosus | FTZ F1 alpha | 0.0068 | 0.0372 | 0.0372 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0068 | 0.0372 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0372 | 0.113 |
Brugia malayi | DNA polymerase family B containing protein | 0.0015 | 0.0002 | 0.0006 |
Mycobacterium tuberculosis | Probable amidase AmiD (acylamidase) (acylase) | 0.0015 | 0 | 0.5 |
Trypanosoma cruzi | extracellular receptor, putative | 0.0037 | 0.0155 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0068 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0023 | 0.006 | 0.0181 |
Echinococcus granulosus | dna polymerase epsilon catalytic subunit a | 0.0015 | 0.0002 | 0.0002 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0123 | 0.0764 | 0.0764 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0023 | 0.006 | 0.0205 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0155 | 0.047 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.01 | 0.0603 | 0.1831 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0044 | 0.0208 | 0.0208 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0068 | 0.0372 | 0.113 |
Loa Loa (eye worm) | glutamate receptor | 0.0391 | 0.2657 | 0.8063 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0121 | 0.0121 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0122 | 0.3922 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0023 | 0.006 | 0.006 |
Trypanosoma brucei | DNA polymerase zeta catalytic subunit, putative | 0.0015 | 0.0002 | 0.0267 |
Schistosoma mansoni | DNA polymerase delta catalytic subunit | 0.0015 | 0.0002 | 0.0002 |
Trypanosoma cruzi | DNA polymerase epsilon catalytic subunit, putative | 0.0015 | 0.0002 | 0.0109 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0023 | 0.006 | 0.006 |
Onchocerca volvulus | 0.0032 | 0.0122 | 0.0424 | |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0003 | 0.0003 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0482 | 0.3295 | 0.3295 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.073 | 0.2215 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0068 | 0.0372 | 0.0372 |
Schistosoma mansoni | DNA polymerase zeta catalytic subunit | 0.0015 | 0.0002 | 0.0002 |
Echinococcus granulosus | GPCR family 3 C terminal | 0.0064 | 0.0343 | 0.0343 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0109 | 0.0109 |
Entamoeba histolytica | DNA polymerase alpha catalytic subunit, putative | 0.0015 | 0.0004 | 0.0174 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0328 | 0.2208 | 0.2208 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.033 | 0.033 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0068 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0391 | 0.2657 | 0.9381 |
Leishmania major | DNA polymerase delta catalytic subunit, putative | 0.0015 | 0.0002 | 0.0109 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0416 | 0.2832 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0191 | 0.1241 | 0.1241 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0068 | 0.0372 | 0.0372 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0482 | 0.3295 | 0.3295 |
Loa Loa (eye worm) | hypothetical protein | 0.0416 | 0.2832 | 0.8595 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0068 | 0.0372 | 0.1315 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0023 | 0.006 | 0.006 |
Trypanosoma brucei | DNA polymerase alpha catalytic subunit | 0.0024 | 0.0063 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0023 | 0.006 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0003 | 0.001 |
Echinococcus multilocularis | DNA polymerase zeta catalytic subunit | 0.0015 | 0.0002 | 0.0002 |
Trichomonas vaginalis | set domain proteins, putative | 0.025 | 0.1659 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0123 | 0.0764 | 0.0764 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0023 | 0.006 | 0.006 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0068 | 0.0372 | 0.113 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0122 | 0.0122 |
Echinococcus multilocularis | DNA polymerase alpha catalytic subunit | 0.0055 | 0.028 | 0.028 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0155 | 0.047 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.02 | 0.1307 | 0.1307 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0133 | 0.083 | 0.083 |
Onchocerca volvulus | 0.0037 | 0.0155 | 0.0541 | |
Brugia malayi | nuclear hormone receptor | 0.0068 | 0.0372 | 0.1315 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0044 | 0.0208 | 0.0631 |
Brugia malayi | nuclear receptor NHR-67 | 0.0023 | 0.006 | 0.0211 |
Brugia malayi | steroid hormone receptor | 0.0068 | 0.0372 | 0.1315 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0068 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | DR-78 | 0.0023 | 0.006 | 0.0181 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0068 | 0.0372 | 0.1315 |
Onchocerca volvulus | 0.025 | 0.1659 | 0.5858 | |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0037 | 0.0155 | 0.0155 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.033 | 0.1164 |
Mycobacterium ulcerans | amidase | 0.0015 | 0 | 0.5 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0003 | 0.0003 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0431 | 0.2934 | 0.2934 |
Echinococcus granulosus | dnaJ subfamily B | 0.0431 | 0.2934 | 0.2934 |
Brugia malayi | hypothetical protein | 0.0023 | 0.006 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0155 | 0.047 |
Echinococcus multilocularis | DNA polymerase delta catalytic subunit | 0.0015 | 0.0002 | 0.0002 |
Echinococcus multilocularis | atrial natriuretic peptide receptor | 0.0037 | 0.0155 | 0.0155 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0068 | 0.0372 | 0.0372 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0023 | 0.006 | 0.006 |
Schistosoma mansoni | coup transcription factor | 0.0068 | 0.0372 | 0.0372 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0068 | 0.0372 | 0.0372 |
Schistosoma mansoni | nuclear hormone receptor | 0.0023 | 0.006 | 0.006 |
Onchocerca volvulus | 0.0068 | 0.0372 | 0.131 | |
Brugia malayi | Nuclear hormone receptor E75 | 0.0023 | 0.006 | 0.0211 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0044 | 0.0208 | 0.0208 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0155 | 0.047 |
Brugia malayi | ecdysteroid receptor | 0.0416 | 0.2832 | 1 |
Plasmodium vivax | DNA polymerase epsilon, catalytic subunit a, putative | 0.0015 | 0.0002 | 0.0082 |
Echinococcus granulosus | DNA polymerase zeta catalytic subunit | 0.0015 | 0.0002 | 0.0002 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0123 | 0.0764 | 0.0764 |
Echinococcus multilocularis | GPCR, family 3, C terminal | 0.0064 | 0.0343 | 0.0343 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0023 | 0.006 | 0.006 |
Echinococcus granulosus | DNA polymerase alpha catalytic subunit | 0.0055 | 0.028 | 0.028 |
Mycobacterium tuberculosis | Probable amidase AmiB2 (aminohydrolase) | 0.0015 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0044 | 0.0208 | 0.0734 |
Mycobacterium tuberculosis | Probable amidase AmiC (aminohydrolase) | 0.0015 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0023 | 0.006 | 0.006 |
Mycobacterium tuberculosis | Possible amidase (aminohydrolase) | 0.0015 | 0 | 0.5 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0037 | 0.0155 | 0.0547 |
Mycobacterium ulcerans | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0015 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0237 | 0.0837 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0133 | 0.083 | 0.083 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.033 | 0.1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0155 | 0.047 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0015 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0068 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0068 | 0.0372 | 0.113 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0068 | 0.0372 | 0.0372 |
Brugia malayi | Guanylyl cyclase protein 23 | 0.0037 | 0.0155 | 0.0547 |
Mycobacterium ulcerans | amidase | 0.0015 | 0 | 0.5 |
Loa Loa (eye worm) | metabotropic glutamate receptor 8 | 0.0037 | 0.0155 | 0.047 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.033 | 0.033 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.01 | 0.0603 | 0.1831 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0122 | 0.0122 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1433 | 1 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0037 | 0.0155 | 0.0155 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0037 | 0.0155 | 0.047 |
Mycobacterium leprae | PROBABLE AMIDASE AMIC (AMINOHYDROLASE) | 0.0015 | 0 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0068 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0372 | 0.113 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0003 | 0.0012 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0068 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0603 | 0.1831 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0023 | 0.006 | 0.0211 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0023 | 0.006 | 0.0211 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0328 | 0.2208 | 0.2208 |
Plasmodium falciparum | DNA polymerase delta catalytic subunit | 0.0015 | 0.0002 | 0.3892 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0023 | 0.006 | 0.006 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0328 | 0.2208 | 0.2208 |
Brugia malayi | hypothetical protein | 0.0023 | 0.006 | 0.0211 |
Echinococcus granulosus | glutamate receptor 2 | 0.0037 | 0.0155 | 0.0155 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0068 | 0.0372 | 0.113 |
Brugia malayi | tailless protein | 0.0023 | 0.006 | 0.0211 |
Plasmodium vivax | DNA polymerase alpha, putative | 0.0044 | 0.0208 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0372 | 0.113 |
Brugia malayi | DNA polymerase family B, exonuclease domain containing protein | 0.0015 | 0.0002 | 0.0006 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0068 | 0.0372 | 0.1315 |
Brugia malayi | nuclear receptor NHR-88 | 0.0068 | 0.0372 | 0.1315 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0068 | 0.0372 | 0.1315 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0068 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Schistosoma mansoni | DNA polymerase alpha catalytic subunit | 0.002 | 0.004 | 0.004 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0023 | 0.006 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0122 | 0.043 |
Trypanosoma brucei | DNA polymerase epsilon catalytic subunit, putative | 0.0015 | 0.0002 | 0.0267 |
Leishmania major | extracellular receptor, putative | 0.0037 | 0.0155 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0044 | 0.0208 | 0.0734 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0123 | 0.0764 | 0.0764 |
Schistosoma mansoni | hypothetical protein | 0.0431 | 0.2934 | 0.2934 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.033 | 0.033 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0023 | 0.006 | 0.006 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0068 | 0.0372 | 0.0372 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0155 | 1 |
Echinococcus granulosus | DNA polymerase delta catalytic subunit | 0.0015 | 0.0002 | 0.0002 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0237 | 0.0837 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0037 | 0.0155 | 0.0155 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0068 | 0.0372 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0237 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Loa Loa (eye worm) | DNA-directed DNA polymerase III | 0.0015 | 0.0002 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0068 | 0.0372 | 0.1315 |
Giardia lamblia | DNA polymerase alpha subunit A | 0.0046 | 0.0221 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0023 | 0.006 | 0.006 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0122 | 0.0122 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0023 | 0.006 | 0.0181 |
Onchocerca volvulus | DNA polymerase alpha catalytic subunit homolog | 0.0075 | 0.0425 | 0.1495 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0372 | 0.113 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0037 | 0.0155 | 0.0155 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0068 | 0.0372 | 0.0372 |
Brugia malayi | hypothetical protein | 0.0279 | 0.1867 | 0.6591 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0037 | 0.0155 | 0.0155 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0068 | 0.0372 | 0.0372 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0037 | 0.0155 | 0.047 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0208 | 0.0631 |
Trichomonas vaginalis | DNA polymerase alpha catalytic subunit, putative | 0.0024 | 0.0063 | 0.0372 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0191 | 0.1241 | 0.4383 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0068 | 0.0372 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0208 | 0.0631 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.033 | 0.033 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0109 | 0.0109 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0044 | 0.0208 | 0.0734 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0109 | 0.033 |
Brugia malayi | nuclear receptor NHR-88 | 0.0023 | 0.006 | 0.0211 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0068 | 0.0372 | 0.0372 |
Echinococcus granulosus | tyrosine kinase | 0.0037 | 0.0155 | 0.0155 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0037 | 0.0155 | 0.0155 |
Brugia malayi | nuclear hormone receptor | 0.0023 | 0.006 | 0.0211 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0068 | 0.0372 | 0.0372 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0023 | 0.006 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.0764 | 0.2317 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.006 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Brugia malayi | hypothetical protein | 0.0044 | 0.0208 | 0.0734 |
Schistosoma mansoni | nuclear hormone receptor | 0.0068 | 0.0372 | 0.0372 |
Mycobacterium ulcerans | peptide amidase, GatA | 0.0015 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0023 | 0.006 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0208 | 0.0631 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0109 | 0.0383 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.033 | 0.033 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0343 | 0.1042 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0044 | 0.0208 | 0.0208 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0068 | 0.0372 | 0.113 |
Brugia malayi | amidase | 0.0123 | 0.0764 | 0.2696 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0023 | 0.006 | 0.0211 |
Brugia malayi | Pre-SET motif family protein | 0.022 | 0.1446 | 0.5106 |
Plasmodium vivax | DNA polymerase zeta catalytic subunit, putative | 0.0015 | 0.0002 | 0.0082 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0068 | 0.0372 | 0.131 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0068 | 0.0372 | 0.0372 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0044 | 0.0208 | 0.0208 |
Brugia malayi | nuclear receptor RXR | 0.0023 | 0.006 | 0.0211 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0237 | 0.0719 |
Brugia malayi | conserved hypotetical protein | 0.0023 | 0.006 | 0.0211 |
Echinococcus granulosus | glutamate receptor 2 | 0.0037 | 0.0155 | 0.0155 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.033 | 0.1164 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Brugia malayi | RNA binding protein | 0.0062 | 0.033 | 0.1164 |
Schistosoma mansoni | protein kinase | 0.0037 | 0.0155 | 0.0155 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0037 | 0.0155 | 0.047 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0003 | 0.0003 |
Onchocerca volvulus | Atrial natriuretic peptide receptor 3 homolog | 0.0037 | 0.0155 | 0.0541 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0003 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0122 | 0.0369 |
Echinococcus multilocularis | tyrosine kinase | 0.0037 | 0.0155 | 0.0155 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0129 | 0.0129 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0023 | 0.006 | 0.0211 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0003 | 0.0003 |
Schistosoma mansoni | nuclear receptor | 0.0023 | 0.006 | 0.006 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0068 | 0.0372 | 0.113 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0037 | 0.0155 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0372 | 0.113 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.033 | 0.033 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0445 | 0.3035 | 0.3035 |
Loa Loa (eye worm) | hypothetical protein | 0.0482 | 0.3295 | 1 |
Onchocerca volvulus | 0.003 | 0.0109 | 0.0378 | |
Echinococcus multilocularis | dna polymerase epsilon catalytic subunit a | 0.0015 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0003 | 0.001 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0037 | 0.0155 | 0.0155 |
Brugia malayi | hypothetical protein | 0.0044 | 0.0208 | 0.0734 |
Trypanosoma cruzi | DNA polymerase delta catalytic subunit, putative | 0.0015 | 0.0002 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0372 | 0.113 |
Onchocerca volvulus | 0.0023 | 0.006 | 0.0205 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0023 | 0.006 | 0.006 |
Mycobacterium leprae | PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) | 0.0015 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0068 | 0.0372 | 0.0372 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0121 | 0.0121 |
Onchocerca volvulus | 0.0023 | 0.006 | 0.0205 | |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0068 | 0.0372 | 0.0372 |
Plasmodium vivax | DNA polymerase delta catalytic subunit, putative | 0.0015 | 0.0002 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0372 | 0.113 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0068 | 0.0372 | 0.1315 |
Schistosoma mansoni | thyroid hormone receptor | 0.02 | 0.1307 | 0.1307 |
Schistosoma mansoni | tyrosine kinase | 0.0037 | 0.0155 | 0.0155 |
Leishmania major | DNA polymerase I alpha catalytic subunit, putative | 0.0024 | 0.0063 | 0.4095 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0023 | 0.006 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0129 | 0.0391 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0355 | 0.2397 | 0.8464 |
Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0037 | 0.0155 | 0.0155 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0068 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.033 | 0.1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0037 | 0.0155 | 0.0155 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0068 | 0.0372 | 0.1315 |
Schistosoma mansoni | DNA polymerase alpha catalytic subunit | 0.0055 | 0.028 | 0.028 |
Onchocerca volvulus | Poor gastrulation protein homolog | 0.0064 | 0.0343 | 0.1208 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0068 | 0.0372 | 0.1315 |
Brugia malayi | ecdysone receptor | 0.0023 | 0.006 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0155 | 0.047 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0208 | 0.0631 |
Trichomonas vaginalis | DNA polymerase II, putative | 0.0024 | 0.0063 | 0.0372 |
Schistosoma mansoni | amidase | 0.0123 | 0.0764 | 0.0764 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0122 | 0.0122 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0003 | 0.0003 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0122 | 0.0122 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.022 | 0.1446 | 0.4389 |
Mycobacterium tuberculosis | Probable amidase AmiA2 (aminohydrolase) | 0.0015 | 0 | 0.5 |
Leishmania major | DNA polymerase epsilon catalytic subunit, putative | 0.0015 | 0.0002 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0208 | 0.0631 |
Schistosoma mansoni | tyrosine kinase | 0.0037 | 0.0155 | 0.0155 |
Mycobacterium ulcerans | amidase | 0.0015 | 0 | 0.5 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0015 | 0 | 0.5 |
Schistosoma mansoni | nuclear receptor | 0.0023 | 0.006 | 0.006 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0129 | 0.0455 |
Trypanosoma cruzi | DNA polymerase I alpha catalytic subunit, putative | 0.0024 | 0.0063 | 0.4095 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0037 | 0.0155 | 0.0155 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0068 | 0.0372 | 0.131 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0068 | 0.0372 | 0.113 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0068 | 0.0372 | 0.113 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0003 | 0.0003 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0122 | 0.0122 |
Mycobacterium ulcerans | amidase | 0.0015 | 0 | 0.5 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.0308 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.02 | 0.1307 | 0.1307 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0023 | 0.006 | 0.006 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.01 | 0.0603 | 0.213 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0068 | 0.0372 | 0.1315 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0015 | 0 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0068 | 0.0372 | 0.0372 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0037 | 0.0155 | 0.0155 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0068 | 0.0372 | 0.0372 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1433 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0068 | 0.0372 | 0.0372 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0037 | 0.0155 | 0.0155 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.033 | 0.1 |
Brugia malayi | DNA polymerase alpha catalytic subunit | 0.0044 | 0.0208 | 0.0733 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0123 | 0.0764 | 0.0764 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0023 | 0.006 | 0.0205 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0425 | 0.1289 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.033 | 0.033 |
Toxoplasma gondii | DNA polymerase (pol2) superfamily protein | 0.0044 | 0.0208 | 0.6734 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0122 | 0.0122 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0068 | 0.0372 | 0.1315 |
Echinococcus granulosus | atrial natriuretic peptide receptor | 0.0037 | 0.0155 | 0.0155 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0122 | 0.5859 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0068 | 0.0372 | 0.1315 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0064 | 0.0343 | 0.1213 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0003 | 0.0003 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0037 | 0.0155 | 0.0547 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0023 | 0.006 | 0.006 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0155 | 0.0547 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0155 | 0.047 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0037 | 0.0155 | 0.0155 |
Echinococcus granulosus | receptor type guanylyl cyclase | 0.0037 | 0.0155 | 0.0155 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0343 | 0.0343 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0121 | 0.0121 |
Schistosoma mansoni | DNA polymerase epsilon catalytic subunit | 0.0015 | 0.0002 | 0.0002 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0068 | 0.0372 | 0.1315 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.0356 | 0.0356 |
Plasmodium falciparum | DNA polymerase alpha catalytic subunit A | 0.0015 | 0.0004 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.083 | 0.083 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0121 | 0.0121 |
Mycobacterium ulcerans | amidase | 0.0015 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase delta catalytic subunit, putative | 0.0015 | 0.0002 | 0.0267 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0068 | 0.0372 | 0.1315 |
Brugia malayi | DNA polymerase delta catalytic subunit | 0.0015 | 0.0002 | 0.0006 |
Onchocerca volvulus | 0.0037 | 0.0155 | 0.0541 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.006 | 0.0181 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0068 | 0.0372 | 0.0372 |
Trypanosoma cruzi | DNA polymerase epsilon catalytic subunit, putative | 0.0015 | 0.0002 | 0.0109 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 61 % | Inhibition of Sprague-Dawley rat brain FAAH assessed as residual activity at 10 uM after 60 mins by reverse phase HPLC-based fluorescence method | ChEMBL. | 22196515 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.