Detailed information for compound 1591881

Basic information

Technical information
  • TDR Targets ID: 1591881
  • Name: 6,7-difluoro-N-(3,4,5-trimethoxyphenyl)quinox alin-2-amine
  • MW: 347.316 | Formula: C17H15F2N3O3
  • H donors: 1 H acceptors: 2 LogP: 3.2 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(Nc2cnc3c(n2)cc(c(c3)F)F)cc(c1OC)OC
  • InChi: 1S/C17H15F2N3O3/c1-23-14-4-9(5-15(24-2)17(14)25-3)21-16-8-20-12-6-10(18)11(19)7-13(12)22-16/h4-8H,1-3H3,(H,21,22)
  • InChiKey: QOPCKPSQKVGMMB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (6,7-difluoroquinoxalin-2-yl)-(3,4,5-trimethoxyphenyl)amine
  • NSC698039
  • NCI60_035022
  • 6,7-Difluoro-N-(3,4,5-trimethoxyphenyl)-2-quinoxalinamine
  • AIDS-152864
  • AIDS152864
  • N-(6,7-Difluoro-2-quinoxalinyl)-N-(3,4,5-trimethoxyphenyl)amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0041 0.0139
Trypanosoma brucei DNA polymerase eta, putative 0.0119 0.0393 0.0601
Brugia malayi Cathepsin L-like precursor 0.0059 0.0167 0.0283
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0008 0.0004
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0093 0.0295 0.0376
Schistosoma mansoni phosphoserine phosphatase 0.0038 0.0086 0.0111
Loa Loa (eye worm) RNA binding protein 0.0061 0.0175 0.0296
Schistosoma mansoni type V p-type atpase isoform 0.0029 0.0052 0.0066
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0018 0.001 0.0013
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.01 0.0321 0.0411
Schistosoma mansoni hypothetical protein 0.005 0.0132 0.0169
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0315 0.1125
Echinococcus granulosus phospholipid transporting ATPase VA 0.0041 0.0097 0.0124
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0397 0.0608
Brugia malayi CHD4 protein 0.0037 0.0085 0.0144
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0021 0.0022 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0074 0.0255
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0059 0.0101
Loa Loa (eye worm) GABA receptor subunit 0.0016 0.0006 0.001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0008
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Trypanosoma brucei calcium-transporting ATPase, putative 0.0112 0.0366 0.0558
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0064 0.0184 0.0299
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0143 0.0183
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0035 0.0182
Onchocerca volvulus 0.0018 0.001 0.0017
Brugia malayi Membrane calcium atpase protein 3 0.0193 0.0673 0.1139
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0069
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0079 0.0274
Trichomonas vaginalis C-MYB, putative 0.0051 0.0137 0.0482
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0034 0.0074 0.0101
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.001
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Brugia malayi SET domain containing protein 0.0037 0.0085 0.0145
Onchocerca volvulus 0.0028 0.0049 0.0083
Brugia malayi GCC2 and GCC3 family protein 0.0029 0.0054 0.0091
Onchocerca volvulus 0.0129 0.0429 0.0727
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.1579 0.5904 1
Giardia lamblia Cathepsin B precursor 0.0034 0.0074 0.0833
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0172 0.0595 0.0911
Toxoplasma gondii proton ATPase, putative 0.0026 0.0041 0.0063
Giardia lamblia Cathepsin L precursor 0.0034 0.0074 0.0833
Leishmania major cathepsin L-like protease 0.0242 0.0857 0.1314
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.0079 0.012
Brugia malayi Animal haem peroxidase family protein 0.009 0.0284 0.048
Brugia malayi Papain family cysteine protease containing protein 0.0074 0.0222 0.0375
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0039 0.0092 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0163 0.0577
Trichomonas vaginalis MYB, putative 0.0051 0.0138 0.0486
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0168 0.0576 0.7203
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0074 0.0094
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0169 0.0216
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0069
Echinococcus multilocularis neurogenic locus notch protein 0.0029 0.0054 0.0069
Brugia malayi dihydrofolate reductase family protein 0.0414 0.1505 0.255
Brugia malayi ImpB/MucB/SamB family protein 0.0093 0.0294 0.0498
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0079 0.0133
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.01 0.0319 0.0529
Entamoeba histolytica cysteine proteinase, putative 0.0074 0.0222 0.2725
Echinococcus granulosus X box binding protein 1 0.0298 0.1068 0.1365
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0034 0.0074 0.0101
Schistosoma mansoni cathepsin F (C01 family) 0.0098 0.0315 0.0403
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0071 0.021 0.0748
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0074 0.0258
Loa Loa (eye worm) hypothetical protein 0.0127 0.0422 0.0715
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0064 0.0184 0.0282
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0039 0.0092 0.0118
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0159 0.0204
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.001
Echinococcus multilocularis protein dispatched 1 0.005 0.0132 0.0169
Onchocerca volvulus 0.0086 0.0268 0.0454
Loa Loa (eye worm) hypothetical protein 0.0034 0.0074 0.0125
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0119 0.0152
Echinococcus multilocularis glycine receptor subunit beta 0.0031 0.0059 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0074 0.0255
Echinococcus multilocularis dnaJ subfamily B 0.0423 0.154 0.1968
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0122 0.0403 0.0682
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0018 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0074 0.0255
Plasmodium falciparum cysteine proteinase falcipain 1 0.0074 0.0222 0.0329
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0062 0.0212
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.0047 0.012 0.1435
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0034 0.0074 0.0109
Brugia malayi Cathepsin L-like precursor 0.0098 0.0315 0.0534
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0226 0.0797 0.0794
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0085 0.0997
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0064 0.0184 0.0299
Schistosoma mansoni DNA polymerase IV / kappa 0.0029 0.0052 0.0067
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Schistosoma mansoni microtubule-associated protein tau 0.2088 0.7825 1
Brugia malayi Animal haem peroxidase family protein 0.009 0.0284 0.048
Schistosoma mansoni rab6-interacting 0.002 0.0021 0.0027
Trichomonas vaginalis pc-MYB2, putative 0.0051 0.0137 0.0482
Brugia malayi hypothetical protein 0.0018 0.001 0.0017
Trichomonas vaginalis cation-transporting ATPase, putative 0.0064 0.0184 0.0653
Echinococcus granulosus glycine receptor subunit alpha 1 0.0031 0.0059 0.0076
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Echinococcus granulosus delta-like protein 1 0.0029 0.0054 0.0069
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0278 0.0994 0.127
Loa Loa (eye worm) hypothetical protein 0.0034 0.0074 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Echinococcus multilocularis Chromo domain 0.0036 0.0079 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0049 0.0166
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0064 0.0184 0.0282
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Loa Loa (eye worm) hypothetical protein 0.0039 0.0092 0.0156
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.01 0.0321 0.0411
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0016 0.0006 0.001
Schistosoma mansoni terminal deoxycytidyl transferase 0.0093 0.0294 0.0375
Entamoeba histolytica phospholipid-transporting ATPase Neo1, putative 0.0029 0.0052 0.0577
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0065 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0397 0.0608
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0034 0.0074 0.0101
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0315 0.1125
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0137 0.0482
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0052 0.0177
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0128 0.0164
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0067 0.0198 0.0252
Schistosoma mansoni phospholipid-transporting atpase 0.0029 0.0052 0.0066
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Echinococcus multilocularis Niemann Pick C1 protein 0.0102 0.0328 0.0419
Mycobacterium tuberculosis Conserved hypothetical protein 0.0093 0.0294 0.0485
Schistosoma mansoni hypothetical protein 0.0298 0.1068 0.1365
Brugia malayi cathepsin F-like cysteine proteinase 0.0034 0.0074 0.0125
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0018 0.0023
Loa Loa (eye worm) ACC-1 protein 0.0031 0.0059 0.0101
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0132 0.0444 0.0752
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0042 0.0104 0.0365
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Brugia malayi cathepsin B-like cysteine proteinase 0.0034 0.0074 0.0125
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0226 0.0797 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0143 0.022
Loa Loa (eye worm) hypothetical protein 0.0071 0.021 0.0356
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.1737 0.6501 1
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0018 0.001 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0005
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0119 0.0179
Onchocerca volvulus 0.0018 0.001 0.0017
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0018 0.001 0.0013
Entamoeba histolytica deoxycytidyl transferase, putative 0.0093 0.0294 0.3637
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.0079 0.0101
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0018 0.001 0.0007
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Schistosoma mansoni patched 1 0.0044 0.0109 0.0139
Trichomonas vaginalis DNA helicase recq, putative 0.0048 0.0124 0.0435
Trypanosoma cruzi cation-transporting ATPase, putative 0.0064 0.0184 0.0181
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.009 0.0316
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0108 0.0351 0.0582
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0145 0.049 0.0817
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0106 0.0343 0.0439
Loa Loa (eye worm) hypothetical protein 0.0034 0.0074 0.0125
Echinococcus multilocularis nAChR subunit 0.0016 0.0006 0.0008
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0159 0.0204
Onchocerca volvulus 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0129 0.043 0.0728
Mycobacterium ulcerans hypothetical protein 0.0029 0.0052 0.0079
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0169 0.0277
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0018 0.001 0.0017
Echinococcus granulosus phospholipid transporting ATPase IF 0.0029 0.0052 0.0066
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.001 0.0013
Brugia malayi hypothetical protein 0.0244 0.0866 0.1468
Onchocerca volvulus 0.0051 0.0137 0.0232
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.000000014634 0.000000018702
Brugia malayi Peroxidasin 0.009 0.0284 0.048
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0362 0.0462
Brugia malayi Doublecortin family protein 0.002 0.0021 0.0035
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.0079 0.012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0079 0.0274
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0036 0.0079 0.0109
Trypanosoma cruzi P-type H+-ATPase, putative 0.0124 0.0413 0.041
Echinococcus granulosus cation transporting ATPase 13A3 0.0064 0.0184 0.0235
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Brugia malayi hypothetical protein 0.0126 0.0419 0.0709
Brugia malayi hypothetical protein 0.002 0.0021 0.0035
Trypanosoma brucei protein tyrosine phosphatase 1 0.0018 0.001 0.0011
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0064 0.0184 0.0312
Leishmania major cathepsin L-like protease 0.0242 0.0857 0.1314
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0064 0.0184 0.0302
Schistosoma mansoni chromobox protein 0.0158 0.054 0.069
Echinococcus granulosus fibropellin Ia 0.0029 0.0054 0.0069
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0029 0.0052 0.0557
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Onchocerca volvulus 0.0018 0.001 0.0017
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0018 0.001 0.0013
Plasmodium vivax unspecified product 0.0074 0.0222 0.0329
Echinococcus multilocularis calcium transporting atpase 0.028 0.1002 0.128
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0343 0.0439
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0016 0.0006 0.0008
Onchocerca volvulus 0.0029 0.0054 0.0091
Loa Loa (eye worm) blistered cuticle protein 3 0.009 0.0284 0.048
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0226 0.0797 0.2861
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0031 0.0059 0.0101
Echinococcus multilocularis tumor protein p63 0.0349 0.1262 0.1613
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.1737 0.6501 1
Echinococcus multilocularis protein patched 0.0044 0.0109 0.0139
Trypanosoma brucei calcium-translocating P-type ATPase 0.028 0.1002 0.1538
Trypanosoma brucei chrX additional, unordered contigs 0.0029 0.0052 0.0077
Schistosoma mansoni alpha-glucosidase 0.0145 0.0491 0.0627
Loa Loa (eye worm) hypothetical protein 0.0146 0.0495 0.0839
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0138 0.0486
Echinococcus granulosus thymidylate synthase 0.1579 0.5904 0.7545
Plasmodium vivax unspecified product 0.0039 0.0092 0.0129
Brugia malayi thymidylate synthase 0.1579 0.5904 1
Schistosoma mansoni hypothetical protein 0.0042 0.0103 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0079 0.0274
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0172 0.0595 0.0592
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0137 0.0482
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.028 0.1002 0.128
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0031 0.0059 0.0101
Plasmodium vivax Adenylate and Guanylate cyclase catalytic domain containing protein 0.0028 0.0049 0.0064
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0085 0.0263 0.026
Leishmania major calcium-transporting ATPase, putative 0.0172 0.0595 0.0911
Onchocerca volvulus 0.0018 0.001 0.0017
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0008 0.0011
Schistosoma mansoni na+/k+ atpase alpha subunit 0.017 0.0587 0.075
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.001
Onchocerca volvulus 0.0018 0.001 0.0017
Schistosoma mansoni rab6-interacting 0.002 0.0021 0.0027
Echinococcus granulosus peroxidasin 0.009 0.0284 0.0362
Trichomonas vaginalis Heterochromatin protein, putative 0.0036 0.0079 0.0274
Echinococcus multilocularis lamin dm0 0.0028 0.0049 0.0063
Echinococcus multilocularis protein kinase c epsilon type 0.0016 0.0005 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Trypanosoma brucei glucosidase, putative 0.0037 0.0085 0.0127
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0016 0.0006 0.001
Loa Loa (eye worm) doublecortin family protein 0.002 0.0021 0.0035
Schistosoma mansoni ATPase 0.0313 0.1126 0.1439
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0226 0.0797 0.2861
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0143 0.0507
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0064 0.0184 0.0653
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0018 0.001 0.0017
Plasmodium falciparum cation-transporting ATPase 1 0.0026 0.0041 0.0052
Trypanosoma cruzi P-type H+-ATPase, putative 0.0124 0.0413 0.041
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0091 0.0286 0.0366
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0018 0.0023
Onchocerca volvulus 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0081 0.025 0.0423
Loa Loa (eye worm) protein tyrosine phosphatase 0.0018 0.001 0.0017
Brugia malayi Heterochromatin protein 1 0.0158 0.054 0.0914
Brugia malayi EGF-like domain containing protein 0.0029 0.0054 0.0091
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0168 0.058 0.0982
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.0258 0.033
Giardia lamblia Cysteine protease 0.0034 0.0074 0.0833
Trichomonas vaginalis chromobox protein, putative 0.0158 0.054 0.1935
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0343 0.0439
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0074 0.0258
Entamoeba histolytica hypothetical protein 0.0024 0.0035 0.0367
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0031 0.0059 0.0101
Schistosoma mansoni notch 0.0029 0.0054 0.0069
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0086 0.027 0.0415
Echinococcus granulosus neuropeptide receptor A26 0.0484 0.1773 0.2265
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0074 0.0833
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0074 0.0125
Onchocerca volvulus 0.0059 0.0167 0.0283
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.0211 0.032
Plasmodium vivax telomerase reverse transcriptase, putative 0.0085 0.0263 0.0393
Trypanosoma brucei telomerase reverse transcriptase 0.0085 0.0263 0.0401
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0006 0.0003
Mycobacterium tuberculosis Hypothetical protein 0.0751 0.2779 0.47
Loa Loa (eye worm) heterochromatin protein 1 0.0158 0.054 0.0914
Echinococcus granulosus glycine receptor subunit alpha 1 0.0031 0.0059 0.0076
Onchocerca volvulus 0.0098 0.0315 0.0534
Echinococcus multilocularis X box binding protein 1 0.0298 0.1068 0.1365
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.0758 0.1284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0167 0.0592
Brugia malayi phospholipid-translocating P-type ATPase, flippase family protein 0.0029 0.0052 0.0088
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0034 0.0074 0.0101
Schistosoma mansoni cathepsin C 0.0034 0.0074 0.0094
Loa Loa (eye worm) animal heme peroxidase 0.009 0.0284 0.048
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Echinococcus granulosus cathepsin l cysteine peptidase 0.0098 0.0315 0.0403
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0038 0.0086 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0074 0.0258
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0296
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0003 0.0003
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0169 0.0259
Trypanosoma cruzi DNA damage repair protein, putative 0.0029 0.0052 0.005
Echinococcus granulosus Niemann Pick C1 protein 0.0102 0.0328 0.0419
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0226 0.0797 0.0794
Trypanosoma cruzi cysteine peptidase, putative 0.0242 0.0857 0.0854
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0175 0.0296
Trichomonas vaginalis DNA polymerase eta, putative 0.012 0.0397 0.1422
Leishmania major cathepsin L-like protease 0.0098 0.0315 0.0481
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0034 0.0074 0.0853
Plasmodium falciparum serine repeat antigen 5 0.0034 0.0074 0.0101
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0128 0.0217
Schistosoma mansoni copper ABC transporter ATPase 0.0064 0.0184 0.0235
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0093 0.0294 0.0375
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0018 0.001 0.0013
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0397 0.0395
Onchocerca volvulus 0.0067 0.0198 0.0335
Brugia malayi M-phase phosphoprotein, mpp8 0.0129 0.0429 0.0727
Trypanosoma cruzi cysteine peptidase, putative 0.2664 1 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0103 0.0334 0.0427
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0051 0.0137 0.165
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0208 0.0729 0.1235
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0051 0.0137 0.165
Onchocerca volvulus 0.01 0.0321 0.0544
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0343 0.0439
Schistosoma mansoni DNA helicase recq1 0.002 0.0018 0.0023
Echinococcus multilocularis dihydrofolate reductase 0.0414 0.1505 0.1924
Brugia malayi intermediate filament protein 0.0028 0.0049 0.0083
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0052 0.0077
Brugia malayi E1-E2 ATPase family protein 0.0127 0.0423 0.0717
Brugia malayi Potential phospholipid-transporting ATPase IA 0.0026 0.0041 0.007
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0046 0.0078
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0037
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0021 0.0027
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0031 0.0059 0.0101
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0175 0.0224
Brugia malayi EGF-like domain containing protein 0.0029 0.0054 0.0091
Echinococcus multilocularis protein kinase c iota type 0.0015 0.0001 0.0001
Giardia lamblia Cathepsin B precursor 0.0034 0.0074 0.0833
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0175 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0005 0.0007
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Brugia malayi hypothetical protein 0.0111 0.0362 0.0613
Brugia malayi cathepsin L precursor 0.0034 0.0074 0.0125
Brugia malayi Protein-tyrosine phosphatase 0.0018 0.001 0.0017
Entamoeba histolytica hypothetical protein 0.0111 0.0362 0.4496
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0026 0.0041 0.0425
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.000000014634 0.000000018702
Schistosoma mansoni cation-transporting atpase fly 0.0026 0.0041 0.0053
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0031 0.0059 0.0076
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0175 0.0224
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0169 0.0273
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0208 0.0729 0.0932
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0074 0.0255
Onchocerca volvulus Peroxidasin homolog 0.009 0.0284 0.048
Loa Loa (eye worm) thymidylate synthase 0.1579 0.5904 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0049 0.0166
Brugia malayi hypothetical protein 0.0018 0.001 0.0017
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0098 0.0315 0.0534
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0086 0.027 0.0268
Schistosoma mansoni neurotransmitter gated ion channel 0.0016 0.0006 0.0008
Plasmodium falciparum serine repeat antigen 8 0.0034 0.0074 0.0101
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0036 0.0079 0.0101
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0226 0.0797 0.1222
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0031 0.0059 0.0101
Toxoplasma gondii P-type ATPase of unknown pump specificity (type V) protein 0.0026 0.0041 0.0063
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0031 0.0059 0.0076
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0034 0.0074 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0143 0.0183
Schistosoma mansoni hypothetical protein 0.0053 0.0146 0.0186
Onchocerca volvulus 0.0018 0.001 0.0017
Echinococcus granulosus cathepsin L cysteine proteinase 0.0098 0.0315 0.0403
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.001
Entamoeba histolytica cysteine proteinase 1, putative 0.0074 0.0222 0.2725
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0029 0.0054 0.0091
Echinococcus granulosus sodium channel protein 0.0148 0.0501 0.064
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.0211 0.032
Onchocerca volvulus 4.1 G protein, putative homolog 0.0018 0.001 0.0017
Onchocerca volvulus Huntingtin homolog 0.0127 0.0422 0.0715
Brugia malayi Cadherin domain containing protein 0.0029 0.0054 0.0091
Onchocerca volvulus 0.0018 0.001 0.0017
Plasmodium falciparum copper-transporting ATPase 0.0064 0.0184 0.0271
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0104 0.0365
Onchocerca volvulus Cathepsin L homolog 0.0098 0.0315 0.0534
Leishmania major copper-transporting ATPase-like protein, putative 0.0064 0.0184 0.0279
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0083 0.029
Echinococcus multilocularis phosphoserine phosphatase 0.0038 0.0086 0.0111
Brugia malayi Protein-tyrosine phosphatase 0.0018 0.001 0.0017
Echinococcus granulosus tar DNA binding protein 0.0061 0.0175 0.0224
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0397 0.0608
Echinococcus multilocularis cation transporting atpase worm 0.0064 0.0184 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0038 0.0129
Loa Loa (eye worm) hypothetical protein 0.0244 0.0866 0.1468
Trichomonas vaginalis chromobox protein, putative 0.01 0.0321 0.1146
Trypanosoma brucei P-type H+-ATPase, putative 0.0124 0.0413 0.0631
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0119 0.0117
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0091 0.0286 0.0366
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0018 0.0031
Schistosoma mansoni hypothetical protein 0.0042 0.0103 0.0131
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0414 0.1505 0.2505
Trichomonas vaginalis cation-transporting ATPase, putative 0.0313 0.1126 0.4046
Echinococcus multilocularis phospholipid transporting ATPase IF 0.0029 0.0052 0.0066
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0112 0.0366 0.0363
Brugia malayi excitatory GABA receptor EXP-1A 0.0031 0.0059 0.0101
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0079 0.0918
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0385 0.0652
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0038 0.0086 0.0132
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.0875 0.1483
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0018 0.001 0.0013
Trypanosoma brucei trypanothione reductase 0.0049 0.0128 0.0193
Onchocerca volvulus 0.0018 0.001 0.0017
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0385 0.0652
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0186 0.0238
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0034 0.0074 0.0101
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Leishmania major cathepsin L-like protease 0.0098 0.0315 0.0481
Schistosoma mansoni nAChR subunit 0.0031 0.0059 0.0076
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0031 0.0059 0.0101
Echinococcus multilocularis neurogenic locus protein delta 0.0029 0.0054 0.0069
Brugia malayi RNA binding protein 0.0061 0.0175 0.0296
Giardia lamblia Cathepsin L precursor 0.0034 0.0074 0.0833
Brugia malayi Cathepsin L-like precursor 0.0098 0.0315 0.0534
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0315 0.1125
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.001
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0222 0.0219
Leishmania major cathepsin L-like protease 0.0098 0.0315 0.0481
Echinococcus multilocularis phospholipid transporting atpase ih phospholipid transporting atpase if 0.0029 0.0052 0.0066
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.011 0.0359 0.4462
Echinococcus granulosus calcium transporting atpase 0.028 0.1002 0.128
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Onchocerca volvulus 0.0018 0.001 0.0017
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0098 0.0315 0.0403
Echinococcus granulosus Protein kinase C brain isozyme 0.0056 0.0154 0.0197
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0031 0.0059 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0074 0.0255
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0031 0.0059 0.0076
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0193 0.0673 0.086
Plasmodium vivax P-type ATPase, putative 0.0026 0.0041 0.0052
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0085 0.0296
Onchocerca volvulus 0.0064 0.0186 0.0315
Schistosoma mansoni nAChR subunit 0.0031 0.0059 0.0076
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0034 0.0074 0.0125
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0064 0.0184 0.0299
Plasmodium vivax calcium-transporting ATPase, putative 0.0316 0.1136 0.1738
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0315 0.1125
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0063 0.0096
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0021 0.0027
Trypanosoma cruzi cysteine peptidase, putative 0.0242 0.0857 0.0854
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0074 0.0255
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0074 0.0094
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0691 0.2552 0.3261
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0063 0.008
Loa Loa (eye worm) hypothetical protein 0.0064 0.0184 0.0312
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0039 0.0092 0.0156
Brugia malayi EGF-like domain containing protein 0.0029 0.0054 0.0091
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0145 0.049 0.0775
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0079 0.0274
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0008 0.0018
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0018 0.001 0.0017
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0175 0.0296
Schistosoma mansoni alpha-glucosidase 0.0145 0.0491 0.0627
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0111 0.0365 0.0605
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0018 0.001 0.005
Trypanosoma cruzi P-type H+-ATPase, putative 0.0086 0.027 0.0268
Echinococcus granulosus lysosomal alpha glucosidase 0.0168 0.058 0.0741
Onchocerca volvulus Neurogenic locus notch homolog 0.0029 0.0054 0.0092
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0037 0.0085 0.0109
Echinococcus multilocularis cathepsin b 0.0034 0.0074 0.0094
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0226 0.0797 0.2861
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0031 0.0059 0.0076
Toxoplasma gondii Copper-exporting ATPase 0.0026 0.0041 0.0063
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0059 0.0101
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0296
Echinococcus granulosus nAChR subunit 0.0031 0.0059 0.0076
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0074 0.0125
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0316 0.1136 0.1452
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0074 0.0222 0.0283
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0052 0.0577
Loa Loa (eye worm) calcium ATPase 0.0142 0.0481 0.0814
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0172 0.0595 0.0592
Echinococcus multilocularis protein jagged 1 0.0029 0.0054 0.0069
Schistosoma mansoni laminin gamma-3 chain 0.0029 0.0054 0.0069
Plasmodium falciparum glutathione reductase 0.0049 0.0128 0.0186
Loa Loa (eye worm) hypothetical protein 0.0102 0.0328 0.0556
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0143 0.0183
Trichomonas vaginalis pten, drome, putative 0.0018 0.001 0.0026
Brugia malayi CXXC zinc finger family protein 0.003 0.0056 0.0095
Giardia lamblia Myb 1-like protein 0.0051 0.0137 0.1643
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0066 0.0194 0.238
Echinococcus multilocularis cpg binding protein 0.0031 0.0062 0.008
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0064 0.0184 0.0235
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0018 0.001 0.0013
Mycobacterium tuberculosis Probable dehydrogenase 0.0111 0.0365 0.0605
Toxoplasma gondii cathepsin B 0.0034 0.0074 0.0112
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0084 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0129
Schistosoma mansoni cathepsin F (C01 family) 0.0098 0.0315 0.0403
Trichomonas vaginalis cation-transporting ATPase, putative 0.0026 0.0041 0.0139
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0138 0.0201
Giardia lamblia Cathepsin L precursor 0.0034 0.0074 0.0833
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Loa Loa (eye worm) hypothetical protein 0.01 0.0321 0.0544
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0035 0.0046
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0049 0.0083
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0064 0.0184 0.0302
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0018 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Echinococcus multilocularis nAChR subunit 0.0031 0.0059 0.0076
Toxoplasma gondii P-type ATPase4, putative 0.0208 0.0729 0.1121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0167 0.0592
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0083 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Echinococcus multilocularis cysteine protease 0.0098 0.0315 0.0403
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0397 0.0608
Plasmodium falciparum cysteine proteinase falcipain 3 0.0098 0.0315 0.0473
Echinococcus multilocularis RNA directed DNA polymerase 0.0039 0.0092 0.0118
Brugia malayi Melibiase family protein 0.0071 0.021 0.0356
Schistosoma mansoni type V p-type atpase isoform 0.0064 0.0184 0.0235
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Echinococcus granulosus cation transporting ATPase 13A1 0.0064 0.0184 0.0235
Chlamydia trachomatis metal transport ATPase 0.0064 0.0184 0.1176
Leishmania major calcium motive p-type ATPase, putative 0.0172 0.0595 0.0911
Onchocerca volvulus Putative cubilin 0.0029 0.0054 0.0091
Giardia lamblia Cysteine protease 0.0034 0.0074 0.0833
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0051 0.0137 0.165
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0138 0.0209
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0098 0.0315 0.0473
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0063 0.008
Trypanosoma cruzi proton motive ATPase 1, putative 0.0038 0.0086 0.0084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0104 0.0365
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0226 0.0797 1
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0228 0.0805 0.1238
Echinococcus granulosus chromobox protein 2 0.0036 0.0079 0.0101
Schistosoma mansoni phospholipid-transporting atpase 0.0029 0.0052 0.0066
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0414 0.1505 0.2543
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0031 0.0059 0.0076
Giardia lamblia Cathepsin L-like protease 0.0034 0.0074 0.0833
Plasmodium vivax serine-repeat antigen (SERA) 0.0034 0.0074 0.0101
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0031 0.0059 0.0101
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0069
Brugia malayi Delta serrate ligand family protein 0.0029 0.0054 0.0091
Schistosoma mansoni intermediate filament proteins 0.0028 0.0049 0.0063
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Entamoeba histolytica cysteine protease, putative 0.0034 0.0074 0.0853
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0006 0.001
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0128 0.0186
Brugia malayi Cation transporter family protein 0.0031 0.0059 0.0101
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0085 0.013
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0021 0.0027
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.001 0.0013
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0143 0.0141
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Onchocerca volvulus 0.0065 0.0191 0.0323
Onchocerca volvulus 0.0205 0.0719 0.1217
Brugia malayi Uncoordinated protein 44 0.0015 0.000000014634 0.000000024786
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0029 0.0052 0.0049
Onchocerca volvulus 0.0018 0.001 0.0017
Onchocerca volvulus Huntingtin homolog 0.0127 0.0422 0.0715
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0362 0.0462
Echinococcus multilocularis dna polymerase eta 0.0119 0.0393 0.0502
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0191 0.0665 0.2384
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0751 0.2779 0.2777
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0018 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.001
Trypanosoma cruzi cysteine proteinase, putative 0.0074 0.0222 0.0219
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0018 0.001 0.0013
Echinococcus multilocularis cathepsin L cysteine protease 0.0098 0.0315 0.0403
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Echinococcus granulosus neurogenic locus notch protein 0.0029 0.0054 0.0069
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0008 0.0008
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0085 0.0109
Schistosoma mansoni lipoxygenase 0.0057 0.0159 0.0204
Leishmania major cathepsin L-like protease 0.0098 0.0315 0.0481
Echinococcus granulosus dnaJ subfamily B 0.0423 0.154 0.1968
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0063 0.008
Loa Loa (eye worm) cathepsin B 0.0034 0.0074 0.0125
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.016 0.0246
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.1579 0.5904 0.7545
Onchocerca volvulus Putative nachr subunit 0.0031 0.0059 0.0101
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0106 0.0343 0.0439
Loa Loa (eye worm) hypothetical protein 0.0059 0.0167 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0074 0.0258
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0074 0.0255
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0111 0.0365 0.0605
Trypanosoma brucei DNA polymerase IV, putative 0.012 0.0397 0.0608
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0074 0.0255
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0031 0.0059 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0397 0.0608
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0098 0.0315 0.1125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0034 0.0074 0.0094
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0074 0.0094
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0203 0.0709 0.0706
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0109 0.0382
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0128 0.0164
Echinococcus multilocularis notch 0.0029 0.0054 0.0069
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0029 0.0052 0.0177
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0003 0.0005
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0119 0.0152
Echinococcus granulosus cysteine protease 0.0074 0.0222 0.0283
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0193 0.0673 0.086
Brugia malayi Cathepsin L-like precursor 0.0098 0.0315 0.0534
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0035 0.0053
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0064 0.0184 0.0653
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0315 0.1125
Leishmania major DNA polymerase eta, putative 0.0119 0.0393 0.0601
Echinococcus multilocularis 0.0018 0.001 0.0013
Echinococcus granulosus nAChR subunit 0.0016 0.0006 0.0008
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0035 0.0042
Leishmania major cathepsin L-like protease 0.0098 0.0315 0.0481
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0029 0.0054 0.0091
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0175 0.0224
Echinococcus granulosus Ankyrin 0.0015 0 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0104 0.0365
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0064 0.0184 0.0181
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0119 0.143
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0018 0.001 0.0017
Echinococcus multilocularis cysteine protease 0.0098 0.0315 0.0403
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0316 0.1136 0.1738
Brugia malayi Animal haem peroxidase family protein 0.009 0.0284 0.048
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0034 0.0074 0.0071
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0008 0.0005
Echinococcus granulosus neurogenic locus notch protein 4 0.0029 0.0054 0.0069
Brugia malayi hypothetical protein 0.0041 0.0097 0.0164
Echinococcus granulosus protein tyrosine phosphatase n9 0.0018 0.001 0.0013
Plasmodium falciparum telomerase reverse transcriptase 0.0085 0.0263 0.0393
Entamoeba histolytica cysteine proteinase, putative 0.0074 0.0222 0.2725
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0083 0.029
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0143 0.0141
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0036 0.0079 0.0101
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0018 0.001 0.0013
Brugia malayi Animal haem peroxidase family protein 0.009 0.0284 0.048
Echinococcus granulosus phospholipid transporting ATPase IA 0.0029 0.0052 0.0066
Plasmodium falciparum serine repeat antigen 3 0.0034 0.0074 0.0101
Leishmania major trypanothione reductase 0.0049 0.0128 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0074 0.0255
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0124 0.0412 0.0642
Giardia lamblia Cathepsin B precursor 0.0034 0.0074 0.0833
Echinococcus granulosus expressed conserved protein 0.0096 0.0305 0.0389
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0029 0.0052 0.0177
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0064 0.0184 0.2249
Onchocerca volvulus Heterochromatin protein 1 homolog 0.01 0.0321 0.0544
Brugia malayi protein kinase C II. 0.0016 0.0005 0.0009
Giardia lamblia Copper-transporting P-type ATPase 0.0064 0.0184 0.2232
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0035 0.005
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0145 0.049 0.0821
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0031 0.0059 0.0101
Trichomonas vaginalis pc-MYB2, putative 0.0051 0.0137 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0298 0.1062
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0124 0.0412 0.0685
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0079 0.0918
Brugia malayi Blistered cuticle protein 3 0.009 0.0284 0.048
Brugia malayi Protein kinase c protein 2 0.0047 0.0122 0.0207
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0018 0.001 0.0013
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0018 0.0023
Echinococcus multilocularis serine threonine protein kinase 0.005 0.0131 0.0167
Giardia lamblia Cathepsin B precursor 0.0034 0.0074 0.0833
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0016 0.0006 0.0008
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0069
Trypanosoma brucei unspecified product 0.0113 0.0372 0.0568
Giardia lamblia Cathepsin B precursor 0.0034 0.0074 0.0833
Loa Loa (eye worm) animal heme peroxidase 0.009 0.0284 0.048
Leishmania major cation-transporting ATPase, putative 0.0026 0.0041 0.006
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0064 0.0184 0.0302
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0079 0.0274
Onchocerca volvulus Peroxidase homolog 0.009 0.0284 0.048
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Loa Loa (eye worm) phospholipid-transporting ATPase ID 0.0029 0.0052 0.0088
Trichomonas vaginalis cation-transporting ATPase, putative 0.0226 0.0797 0.2861
Brugia malayi Muscle positioning protein 4 0.0029 0.0054 0.0091
Plasmodium vivax cation transporting ATPase, putative 0.0064 0.0184 0.0271
Loa Loa (eye worm) hypothetical protein 0.0059 0.0167 0.0283
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0034 0.0074 0.0101
Entamoeba histolytica cysteine protease, putative 0.0098 0.0315 0.3906
Leishmania major DNA polymerase kappa, putative 0.0029 0.0052 0.0077
Brugia malayi Thioredoxin reductase 0.0049 0.0128 0.0217
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0079 0.0274
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0691 0.2552 0.3261
Trypanosoma cruzi phospholipid-translocating ATPase, putative 0.0029 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Entamoeba histolytica hypothetical protein 0.0111 0.0362 0.4496
Onchocerca volvulus 0.0028 0.0049 0.0083
Entamoeba histolytica hypothetical protein 0.0111 0.0362 0.4496
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0056 0.0095
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0229 0.0807 0.1032
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0397 0.0608
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0018 0.0031
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0226 0.0797 0.2861
Echinococcus granulosus neuropeptide s receptor 0.0484 0.1773 0.2265
Brugia malayi Telomerase reverse transcriptase 0.0225 0.0793 0.1343
Brugia malayi Calcium binding EGF domain containing protein 0.0029 0.0054 0.0091
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0313 0.1126 0.1439
Echinococcus granulosus chromobox protein 1 0.0158 0.054 0.069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Loa Loa (eye worm) hypothetical protein 0.0026 0.0041 0.007
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Onchocerca volvulus Peroxidasin homolog 0.009 0.0284 0.048
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0026 0.0041 0.0139
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0059 0.0101
Entamoeba histolytica hypothetical protein 0.0036 0.0079 0.0918
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0018 0.001 0.0017
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0031 0.0059 0.0076
Schistosoma mansoni hypothetical protein 0.0023 0.0031 0.004
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0018 0.001 0.0007
Onchocerca volvulus Chorion peroxidase homolog 0.009 0.0284 0.048
Trypanosoma cruzi cysteine protease, putative 0.0074 0.0222 0.0219
Loa Loa (eye worm) hypothetical protein 0.01 0.0321 0.0544
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0074 0.0114
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0313 0.1126 0.1439
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0085 0.0082
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0143 0.0507
Entamoeba histolytica cysteine proteinase 2 0.0074 0.0222 0.2725
Leishmania major DNA polymerase kappa, putative 0.01 0.0319 0.0487
Loa Loa (eye worm) animal heme peroxidase 0.009 0.0284 0.048
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.004 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0092 0.0323
Onchocerca volvulus 0.0029 0.0054 0.0091
Loa Loa (eye worm) hypothetical protein 0.0051 0.0137 0.0232
Brugia malayi calcium ATPase 0.0107 0.0346 0.0586
Brugia malayi CHE-14 protein 0.0044 0.0109 0.0184
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0018 0.001 0.0017
Schistosoma mansoni slit 0.0029 0.0054 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0129
Brugia malayi TAR-binding protein 0.0061 0.0175 0.0296
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0156 0.0236
Brugia malayi cathepsin Z-like cysteine proteinase 0.0034 0.0074 0.0125
Brugia malayi Protein kinase domain containing protein 0.0016 0.0002 0.0004
Schistosoma mansoni hypothetical protein 0.1191 0.4441 0.5675
Onchocerca volvulus 0.0097 0.0312 0.0528
Trypanosoma brucei phospholipid-transporting ATPase, putative 0.0026 0.0041 0.006
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0018 0.001 0.0013
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0018 0.001 0.0013
Trypanosoma brucei cation-transporting ATPase, putative 0.0064 0.0184 0.0279
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.022 0.0773 0.1309
Brugia malayi hypothetical protein 0.0033 0.0069 0.0118
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0137 0.0482
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0138 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0034 0.0074 0.0255
Onchocerca volvulus 0.0018 0.001 0.0017
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Onchocerca volvulus 0.1579 0.5904 1
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0026 0.0041 0.0425
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0018 0.001 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0119 0.042
Onchocerca volvulus Dual oxidase homolog 0.009 0.0284 0.048
Echinococcus multilocularis jun protein 0.0083 0.0258 0.033
Treponema pallidum hypothetical protein 0.0038 0.0086 0.4465
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0074 0.0094
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0031 0.004
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.001 0.0013
Toxoplasma gondii cathepsin CPL 0.0098 0.0315 0.0484
Onchocerca volvulus 0.0098 0.0315 0.0534
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0222 0.0788
Schistosoma mansoni hypothetical protein 0.1191 0.4441 0.5675
Toxoplasma gondii RNA-directed DNA polymerase 0.0085 0.0263 0.0404
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.0258 0.033
Loa Loa (eye worm) hypothetical protein 0.0086 0.0268 0.0454
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0018 0.001 0.0013
Echinococcus granulosus cathepsin L cysteine protease 0.0074 0.0222 0.0283
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Brugia malayi Glycosyl hydrolases family 31 protein 0.0168 0.058 0.0982
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0064 0.0184 0.0254
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0042 0.0103 0.0131
Loa Loa (eye worm) hypothetical protein 0.0059 0.0167 0.0283
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0055 0.0152 0.0233
Echinococcus multilocularis cation transporting ATPase 13A3 0.0064 0.0184 0.0235
Schistosoma mansoni lamin 0.0028 0.0049 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0005
Echinococcus granulosus protein jagged 2 0.0029 0.0054 0.0069
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0296
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0193 0.0673 0.1034
Leishmania major hypothetical protein, conserved 0.0051 0.0138 0.0209
Schistosoma mansoni cation-transporting ATPase 0.0064 0.0184 0.0235
Onchocerca volvulus 0.0016 0.0006 0.001
Loa Loa (eye worm) CHromoDomain protein family member 0.0037 0.0085 0.0144
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0037 0.0085 0.0109
Trichomonas vaginalis MYB72, putative 0.0051 0.0137 0.0482
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0328 0.1182 0.2001
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0049 0.0166
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0143 0.0216
Onchocerca volvulus 0.0029 0.0054 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Brugia malayi hypothetical protein 0.0018 0.001 0.0017
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.1737 0.6501 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0074 0.0125
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0143 0.1718
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0063 0.008
Loa Loa (eye worm) hypothetical protein 0.0091 0.0286 0.0485
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0018 0.001 0.0013
Leishmania major calcium-translocating P-type ATPase 0.0313 0.1126 0.1729
Onchocerca volvulus 0.0016 0.0006 0.001
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0132 0.0224
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0063 0.008
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0018 0.001 0.0013
Schistosoma mansoni loxhd1 0.002 0.0021 0.0027
Mycobacterium ulcerans DNA polymerase IV 0.012 0.0397 0.0664
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0018 0.001 0.0013
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0018 0.001 0.0013
Echinococcus multilocularis cation transporting ATPase 13A1 0.0064 0.0184 0.0235
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0008 0.001
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0018 0.001 0.0013
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0018 0.001 0.0013
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0064 0.0184 0.0653
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0035 0.0053
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0074 0.0222 0.0283
Echinococcus multilocularis protein jagged 2 0.0029 0.0054 0.0069
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0175 0.0224
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0031 0.0059 0.0076
Entamoeba histolytica cysteine protease, putative 0.0034 0.0074 0.0853
Echinococcus granulosus neurogenic locus notch protein 0.0029 0.0054 0.0069
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0086 0.027 0.0268
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0143 0.0183
Loa Loa (eye worm) hypothetical protein 0.0036 0.0079 0.0133
Loa Loa (eye worm) hypothetical protein 0.0107 0.0349 0.059
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0051 0.0137 0.165
Onchocerca volvulus Cathepsin F homolog 0.0098 0.0315 0.0534
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0691 0.2552 0.3261
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0268 0.0343
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0138 0.0201
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.058 0.0741
Leishmania major aminophospholipid translocase, putative 0.0029 0.0052 0.0075
Loa Loa (eye worm) hypothetical protein 0.0119 0.0393 0.0666
Loa Loa (eye worm) hypothetical protein 0.0039 0.0092 0.0156
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0 0.0001
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0268 0.0343
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.017 0.0587 0.7334
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0137 0.0482
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0036 0.0079 0.012
Brugia malayi cathepsin L-like precursor 0.0059 0.0167 0.0283
Onchocerca volvulus 0.0026 0.0041 0.007
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0052 0.0577
Echinococcus granulosus jun protein 0.0083 0.0258 0.033
Brugia malayi ImpB/MucB/SamB family protein 0.0119 0.0393 0.0666
Loa Loa (eye worm) glutathione reductase 0.0049 0.0128 0.0217
Brugia malayi Cathepsin L-like precursor 0.0098 0.0315 0.0534
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0031
Leishmania major cathepsin L-like protease 0.0242 0.0857 0.1314
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0005
Echinococcus multilocularis neuropeptide s receptor 0.0484 0.1773 0.2265
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Onchocerca volvulus 0.003 0.0056 0.0095
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0049 0.0083
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0098 0.0315 0.0534
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Trichomonas vaginalis set domain proteins, putative 0.0245 0.087 0.3125
Entamoeba histolytica cysteine protease, putative 0.0034 0.0074 0.0853
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0143 0.0507
Loa Loa (eye worm) hypothetical protein 0.0051 0.0138 0.0234
Onchocerca volvulus 0.0018 0.001 0.0017
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0056 0.0154 0.0197
Trypanosoma cruzi cysteine peptidase, putative 0.0098 0.0315 0.0312
Entamoeba histolytica cysteine protease, putative 0.0034 0.0074 0.0853
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0064 0.0184 0.0181
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0098 0.0315 0.1125
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0079 0.0918
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Echinococcus granulosus dna polymerase eta 0.0119 0.0393 0.0502
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0169 0.0216
Brugia malayi cathepsin L-like cysteine proteinase 0.0034 0.0074 0.0125
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0074 0.0094
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.000000014634 0.000000018702
Schistosoma mansoni septate junction protein 0.0029 0.0054 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0071 0.021 0.0269
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.1579 0.5904 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0059 0.0101
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0309 0.1112 0.1884
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0064 0.0184 0.0235
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.012 0.0397 0.1422
Echinococcus granulosus Chromobox protein 3 0.0036 0.0079 0.0101
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0079 0.0274
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0074 0.0094
Trypanosoma brucei unspecified product 0.0064 0.0185 0.0281
Schistosoma mansoni atypical protein kinase C 0.0015 0.0001 0.0001
Mycobacterium ulcerans thymidylate synthase 0.1579 0.5904 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0018 0.001 0.0013
Onchocerca volvulus 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0079 0.0133
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0036 0.0078 0.01
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0052 0.0577
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0064 0.0184 0.0312
Echinococcus granulosus cathepsin L 0.0034 0.0074 0.0094
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0021 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0143 0.0243
Brugia malayi calcium ATPase 0.0086 0.027 0.0458
Plasmodium vivax serine-repeat antigen (SERA) 0.0034 0.0074 0.0101
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0074 0.0222 0.0283
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0018 0.001 0.0013
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.0866 0.1107
Echinococcus multilocularis slit 2 protein 0.0029 0.0054 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0162
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0313 0.1126 0.1124
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Schistosoma mansoni chromobox protein 0.0036 0.0079 0.0101
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0005
Loa Loa (eye worm) calcium ATPase 0.0047 0.012 0.0203
Onchocerca volvulus Peroxidase homolog 0.009 0.0284 0.048
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0098 0.0315 0.0403
Echinococcus granulosus dna polymerase kappa 0.012 0.0397 0.0508
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0226 0.0797 0.1222
Brugia malayi Cation transporter family protein 0.0031 0.0059 0.0101
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0008 0.0008
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0193 0.0673 0.086
Echinococcus multilocularis Niemann Pick C1 protein 0.0145 0.0493 0.063
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0069
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0231 0.0295
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0064 0.0184 0.0302
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0098 0.0315 0.0473
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Plasmodium vivax SET domain protein, putative 0.0032 0.0063 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0119 0.042
Schistosoma mansoni notch 0.0029 0.0054 0.0069
Onchocerca volvulus 0.0018 0.001 0.0017
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0031 0.0059 0.0101
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0085 0.0144
Echinococcus multilocularis chromobox protein 1 0.0158 0.054 0.069
Brugia malayi Valyl-tRNA synthetase 0.0036 0.0079 0.0133
Echinococcus granulosus copper transporting ATPase 1 0.0064 0.0184 0.0235
Schistosoma mansoni hypothetical protein 0.0423 0.154 0.1968
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0052 0.005
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0315 0.1125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0315 0.1125
Giardia lamblia DINP protein human, muc B family 0.01 0.0319 0.3949
Echinococcus multilocularis glycine receptor subunit beta 0.0031 0.0059 0.0076
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0018 0.0016
Onchocerca volvulus 0.0098 0.0315 0.0534
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Brugia malayi hypothetical protein 0.0051 0.0138 0.0234
Leishmania major cytochrome p450-like protein 0.0016 0.0006 0.0005
Plasmodium falciparum phospholipid-transporting ATPase, putative 0.0029 0.0052 0.0068
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.0866 0.1107
Onchocerca volvulus 0.0129 0.0429 0.0727
Entamoeba histolytica hypothetical protein 0.0036 0.0079 0.0918
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0085 0.0263 0.026
Giardia lamblia Cysteine protease 0.0034 0.0074 0.0833
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0074 0.0255
Schistosoma mansoni peroxidasin 0.009 0.0284 0.0362
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0298 0.1062
Schistosoma mansoni nAChR subunit 0.0031 0.0059 0.0076
Onchocerca volvulus 0.009 0.0284 0.048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0315 0.1125
Echinococcus granulosus cathepsin l1 0.0059 0.0167 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0005
Brugia malayi Calcium binding EGF domain containing protein 0.0029 0.0054 0.0091
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Echinococcus multilocularis thymidylate synthase 0.1579 0.5904 0.7545
Loa Loa (eye worm) hypothetical protein 0.0039 0.0092 0.0156
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0027 0.0037
Entamoeba histolytica cysteine proteinase, putative 0.0059 0.0167 0.2035
Onchocerca volvulus 0.0029 0.0054 0.0091
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.001
Echinococcus granulosus glycine receptor subunit alpha 1 0.0031 0.0059 0.0076
Schistosoma mansoni cathepsin s 0.0039 0.0092 0.0117
Loa Loa (eye worm) dihydrofolate reductase 0.0414 0.1505 0.255
Loa Loa (eye worm) ctsf protein 0.0098 0.0315 0.0534
Trichomonas vaginalis cation-transporting ATPase, putative 0.0313 0.1126 0.4046
Echinococcus multilocularis neurogenic locus protein delta 0.0029 0.0054 0.0069
Brugia malayi EGF-like domain containing protein 0.0029 0.0054 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0104 0.0365
Echinococcus granulosus RNA directed DNA polymerase 0.0039 0.0092 0.0118
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0064 0.0184 0.2249
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0138 0.0136
Entamoeba histolytica cysteine proteinase, putative 0.0074 0.0222 0.2725
Loa Loa (eye worm) hypothetical protein 0.0056 0.0156 0.0265
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0031 0.0059 0.0101
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0093 0.0295 0.0376
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0109 0.0139
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0041 0.0097 0.0148
Leishmania major proton motive ATPase, putative 0.0064 0.0184 0.0279
Echinococcus multilocularis expressed conserved protein 0.0096 0.0305 0.0389
Echinococcus granulosus protein kinase C gamma type 0.005 0.0131 0.0167
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0037 0.0085 0.0109
Echinococcus multilocularis phosphoserine phosphatase 0.0038 0.0086 0.0111
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0129
Schistosoma mansoni lipoxygenase 0.002 0.0021 0.0027
Echinococcus multilocularis cathepsin L 0.0034 0.0074 0.0094
Giardia lamblia High cysteine protein 0.0029 0.0054 0.0581
Schistosoma mansoni cpg binding protein 0.003 0.0056 0.0072
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0109 0.0139
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0059 0.0101
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Echinococcus granulosus geminin 0.1191 0.4441 0.5675
Trypanosoma brucei protein kinase, putative 0.0053 0.0143 0.0216
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0052 0.0177
Brugia malayi cathepsin Z-like cysteine proteinase 0.0034 0.0074 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0052 0.005
Loa Loa (eye worm) hypothetical protein 0.0034 0.0074 0.0125
Onchocerca volvulus 0.0098 0.0315 0.0534
Echinococcus granulosus glycine receptor subunit beta 0.0031 0.0059 0.0076
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0313 0.1126 0.1907
Echinococcus multilocularis neural cadherin 0.0029 0.0054 0.0069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0315 0.1125
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0018 0.001 0.0013
Echinococcus granulosus cpg binding protein 0.0031 0.0062 0.008
Trypanosoma brucei cysteine peptidase C (CPC) 0.0034 0.0074 0.0109
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0137 0.0482
Schistosoma mansoni cpg binding protein 0.0031 0.0062 0.008
Echinococcus multilocularis phosphoserine phosphatase 0.0038 0.0086 0.0111
Plasmodium vivax DNA repair protein REV1, putative 0.0029 0.0052 0.0069
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0079 0.0101
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0051 0.0137 0.165
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Echinococcus multilocularis peroxidasin 0.009 0.0284 0.0362
Trypanosoma cruzi DNA polymerase eta, putative 0.0055 0.0152 0.0149
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0052 0.0177
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0226 0.0797 0.1222
Loa Loa (eye worm) hypothetical protein 0.0053 0.0146 0.0247
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0008 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0129
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0031 0.0059 0.0076
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0226 0.0797 1
Echinococcus granulosus neurogenic locus protein delta 0.0029 0.0054 0.0069
Brugia malayi Cathepsin L-like precursor 0.0059 0.0167 0.0283
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0316 0.1136 0.1748
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0074 0.0255
Schistosoma mansoni polycystin 1-related 0.002 0.0021 0.0027
Toxoplasma gondii cathepsin CPC2 0.0034 0.0074 0.0112
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0074 0.0833
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0119 0.042
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0034 0.0074 0.0101
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Schistosoma mansoni notch 0.0029 0.0054 0.0069
Schistosoma mansoni DNA helicase recq5 0.002 0.0018 0.0023
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0021 0.0027
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0018 0.0023
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0119 0.143
Loa Loa (eye worm) RecQ helicase 0.0048 0.0124 0.0209
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0029 0.0052 0.0049
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0143 0.0141
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.008 0.0245 0.0313
Echinococcus multilocularis geminin 0.1191 0.4441 0.5675
Schistosoma mansoni cell polarity protein 0.0029 0.0054 0.0069
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0137 0.0482
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0074 0.0833
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0018 0.001 0.0013
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0018 0.001 0.0013
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0169 0.0277
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0138 0.0212
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0119 0.0179
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0169 0.0256
Entamoeba histolytica cysteine protease, putative 0.0034 0.0074 0.0853
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Echinococcus multilocularis bloom syndrome protein 0.0048 0.0124 0.0158
Schistosoma mansoni notch 0.0029 0.0054 0.0069
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0092 0.0323
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0111 0.0365 0.0562
Mycobacterium tuberculosis Probable oxidoreductase 0.0272 0.0969 0.163
Echinococcus multilocularis RUN 0.002 0.0021 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0079 0.0274
Mycobacterium ulcerans short chain dehydrogenase 0.0272 0.0969 0.1633
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0085 0.0127
Loa Loa (eye worm) hypothetical protein 0.0036 0.0079 0.0133
Schistosoma mansoni protein tyrosine phosphatase 0.0018 0.001 0.0013
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0085 0.0296
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Schistosoma mansoni hypothetical protein 0.0068 0.0199 0.0255
Echinococcus multilocularis hypothetical protein 0.0018 0.001 0.0013
Brugia malayi Cathepsin L-like precursor 0.0098 0.0315 0.0534
Echinococcus granulosus microtubule associated protein 2 0.2088 0.7825 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0119 0.0202
Brugia malayi bZIP transcription factor family protein 0.0083 0.0258 0.0438
Plasmodium falciparum serine repeat antigen 4 0.0034 0.0074 0.0101
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0064 0.0184 0.0302
Loa Loa (eye worm) hypothetical protein 0.0094 0.0298 0.0504
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0034 0.0074 0.0101
Brugia malayi chromobox protein homolog 3 0.0094 0.0298 0.0504
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Giardia lamblia Cathepsin L precursor 0.0034 0.0074 0.0833
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0016 0.0006 0.001
Schistosoma mansoni nAChR subunit 0.0031 0.0059 0.0076
Schistosoma mansoni chromobox protein 0.0158 0.054 0.069
Onchocerca volvulus 0.005 0.0132 0.0224
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0226 0.0797 0.1222
Onchocerca volvulus Cathepsin L homolog 0.0098 0.0315 0.0534
Brugia malayi MH2 domain containing protein 0.0117 0.0385 0.0652
Loa Loa (eye worm) E1-E2 ATPase 0.0124 0.0413 0.0699
Schistosoma mansoni chromobox protein 0.0036 0.0079 0.0101
Brugia malayi EGF-like domain containing protein 0.0029 0.0054 0.0091
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0111 0.0365 0.0605
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0031 0.0059 0.0076
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0008 0.0004
Onchocerca volvulus 0.0018 0.001 0.0017
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0049 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0038 0.0129
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0018 0.001 0.0013
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0064 0.0184 0.0235
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0229 0.0807 0.2898
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0397 0.0395
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0017 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0104 0.0365
Loa Loa (eye worm) hypothetical protein 0.0061 0.0173 0.0293
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0691 0.2552 0.4322
Leishmania major DNA damage repair protein, putative 0.0029 0.0052 0.0077
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0086 0.027 0.0458
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0104 0.0365
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0119 0.0179
Echinococcus granulosus protein jagged 1 0.0029 0.0054 0.0069
Brugia malayi Cathepsin L-like precursor 0.0098 0.0315 0.0534
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0226 0.0797 0.1222
Mycobacterium ulcerans DNA polymerase IV 0.012 0.0397 0.0664
Schistosoma mansoni hypothetical protein 0.002 0.0021 0.0027
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0343 0.0439
Plasmodium falciparum DNA repair protein REV1, putative 0.0029 0.0052 0.0069
Echinococcus multilocularis sodium channel protein 0.0148 0.0501 0.064
Plasmodium falciparum thioredoxin reductase 0.0049 0.0128 0.0186
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0018 0.0027
Loa Loa (eye worm) LGC-31 protein 0.0031 0.0059 0.0101
Echinococcus granulosus Na:K ATPase alpha subunit 0.017 0.0587 0.075
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0193 0.0673 0.086
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0169 0.0216
Echinococcus granulosus neural cadherin 0.0029 0.0054 0.0069
Entamoeba histolytica hypothetical protein 0.0034 0.0074 0.0853
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0008 0.0005
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0031 0.0059 0.0076
Loa Loa (eye worm) animal heme peroxidase 0.009 0.0284 0.048
Leishmania major dihydrofolate reductase-thymidylate synthase 0.1737 0.6501 1
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0041 0.0446
Loa Loa (eye worm) hypothetical protein 0.0045 0.0115 0.0195
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0026 0.0041 0.0425
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0031 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0093 0.0294 0.0498
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0079 0.0274
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Loa Loa (eye worm) hypothetical protein 0.0127 0.0422 0.0715
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0038 0.0086 0.0084
Trypanosoma cruzi major cysteine proteinase, putative 0.0034 0.0074 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Echinococcus granulosus lamin dm0 0.0028 0.0049 0.0063
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Plasmodium falciparum cation transporting P-ATPase 0.0026 0.0041 0.0052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Onchocerca volvulus 0.0018 0.001 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0038 0.0129
Giardia lamblia Telomerase catalytic subunit 0.0085 0.0263 0.3233
Brugia malayi hypothetical protein 0.0127 0.0422 0.0715
Trypanosoma brucei DNA polymerase IV, putative 0.0113 0.0372 0.0568
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0109 0.0184
Chlamydia trachomatis dihydrofolate reductase 0.0414 0.1505 1
Plasmodium vivax copper-transporting ATPase, putative 0.0064 0.0184 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0079 0.0274
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Leishmania major P-type H -ATPase, putative 0.0124 0.0413 0.0631
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0042 0.0104 0.0365
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0074 0.0255
Schistosoma mansoni hypothetical protein 0.0036 0.0079 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0163 0.0577
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0751 0.2779 1
Plasmodium falciparum serine repeat antigen 9 0.0034 0.0074 0.0101
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.028 0.1002 0.1697
Giardia lamblia Cation-transporting ATPase 2, putative 0.0026 0.0041 0.0425
Schistosoma mansoni phospholipid-transporting atpase 0.0028 0.0049 0.0063
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0052 0.0077
Trypanosoma cruzi major cysteine proteinase, putative 0.0178 0.0615 0.0613
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0074 0.0125
Plasmodium vivax vivapain-2 0.0098 0.0315 0.0473
Brugia malayi hypothetical protein 0.0018 0.001 0.0017
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0031 0.0059 0.0076
Brugia malayi follicle stimulating hormone receptor 0.0247 0.0875 0.1483
Onchocerca volvulus 0.0018 0.001 0.0017
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0031 0.0059 0.0101
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0006 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0079 0.0274
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0063 0.008
Brugia malayi hypothetical protein 0.009 0.0284 0.048
Loa Loa (eye worm) fibroinase 0.0098 0.0315 0.0534
Schistosoma mansoni notch 0.0029 0.0054 0.0069
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Schistosoma mansoni cpg binding protein 0.0031 0.0062 0.008
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0296
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0021 0.0027
Brugia malayi MAP kinase sur-1 0.0053 0.0143 0.0243
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0018 0.001 0.0013
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0035 1
Schistosoma mansoni hypothetical protein 0.0042 0.0103 0.0131
Echinococcus granulosus glycine receptor subunit beta 0.0031 0.0059 0.0076
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0034 0.0074 0.0125
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0093 0.0295 0.0376
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0064 0.0184 0.0302
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0226 0.0797 0.2861
Trypanosoma brucei phospholipid-transporting ATPase 1-like protein, putative 0.0029 0.0052 0.0075
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0085 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0034 0.0074 0.0255
Schistosoma mansoni ATPase 0.0313 0.1126 0.1439
Echinococcus multilocularis chromobox protein 2 0.0036 0.0079 0.0101
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Schistosoma mansoni protein tyrosine phosphatase 0.0018 0.001 0.0013
Brugia malayi Cytochrome P450 family protein 0.0016 0.0006 0.001
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0034 0.0074 0.0094
Plasmodium falciparum heterochromatin protein 1 0.0036 0.0079 0.0109
Echinococcus granulosus protein kinase c iota type 0.0015 0.0001 0.0001
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0018 0.001 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.0211 0.032
Onchocerca volvulus 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0034 0.0074 0.0125
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.014 0.047 0.5872
Onchocerca volvulus 0.0246 0.0871 0.1475
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0018 0.001 0.0013
Brugia malayi notch-like transmembrane receptor 0.0029 0.0054 0.0091
Trypanosoma cruzi DNA damage repair protein, putative 0.0029 0.0052 0.005
Brugia malayi Papain family cysteine protease containing protein 0.0074 0.0222 0.0375
Trichomonas vaginalis cation-transporting ATPase, putative 0.0124 0.0413 0.1478
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0093 0.0295 0.0376
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0128 0.0204
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0102 0.0328 0.407
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0231 0.0295
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0015 0 0.0001
Trypanosoma brucei P-type H+-ATPase, putative 0.0124 0.0413 0.0631
Echinococcus multilocularis cathepsin L 0.0074 0.0222 0.0283
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0079 0.0109
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0143 0.0216
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0031 0.0059 0.0076
Schistosoma mansoni cathepsin F (C01 family) 0.0059 0.0167 0.0213
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0193 0.0673 0.086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Schistosoma mansoni jun-related protein 0.0068 0.0199 0.0255
Onchocerca volvulus 0.002 0.0021 0.0035
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0142 0.0481 0.6003
Brugia malayi hypothetical protein 0.0751 0.2779 0.4707
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0085 0.0144
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0018 0.001 0.005
Schistosoma mansoni protein tyrosine phosphatase 0.0018 0.001 0.0013
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0041 0.01 0.0169
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0026 0.0041 0.0139
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0119 0.0202
Brugia malayi cathepsin F-like cysteine proteinase 0.0039 0.0092 0.0156
Leishmania major tyrosine specific protein phosphatase, putative 0.0018 0.001 0.0011
Giardia lamblia Hypothetical protein 0.0034 0.0074 0.0833
Schistosoma mansoni lamin 0.0028 0.0049 0.0063
Onchocerca volvulus 0.0031 0.0059 0.0101
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0029 0.0052 0.0177
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0315 0.3906
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0018 0.0027
Echinococcus multilocularis cathepsin b 0.0034 0.0074 0.0094
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0102 0.0145
Treponema pallidum cation-transporting ATPase, P-type 0.0064 0.0184 1
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.008 0.0245 0.0414
Toxoplasma gondii EGF family domain-containing protein 0.0029 0.0054 0.0082
Echinococcus multilocularis fibropellin Ia 0.0029 0.0054 0.0069
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0137 0.0175
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0029 0.0052 0.0177
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0111 0.0365 0.0605
Onchocerca volvulus 0.0098 0.0315 0.0534
Echinococcus multilocularis phosphoserine phosphatase 0.0038 0.0086 0.0111
Leishmania major P-type H -ATPase, putative 0.0124 0.0413 0.0631
Onchocerca volvulus 0.0029 0.0054 0.0091
Giardia lamblia Cathepsin L-like protease 0.0034 0.0074 0.0833
Brugia malayi Cation transporter family protein 0.01 0.0321 0.0544
Brugia malayi hypothetical protein 0.0065 0.0191 0.0323
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.1737 0.6501 1
Plasmodium falciparum E1-E2 ATPase, putative 0.0026 0.0041 0.0052
Brugia malayi Dihydrofolate reductase 0.0414 0.1505 0.255
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0175 0.0296
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0169 0.0277
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0031 0.0059 0.0101
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0316 0.1136 0.1452
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0005
Trypanosoma brucei DNA damage repair protein, putative 0.0029 0.0052 0.0077
Echinococcus granulosus cathepsin b 0.0034 0.0074 0.0094
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0315
Entamoeba histolytica hypothetical protein 0.0111 0.0362 0.4496
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0222 0.0337
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0143 0.0141
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0064 0.0184 0.0254
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0085 0.0997
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0041 0.0053
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0106 0.0343 0.0439
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0169 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0085 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0397 0.0608
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Schistosoma mansoni notch 0.0029 0.0054 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0079 0.0274
Toxoplasma gondii preprocathepsin c precursor, putative 0.0034 0.0074 0.0112
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0031 0.0059 0.0101
Giardia lamblia Cathepsin B precursor 0.0034 0.0074 0.0833
Brugia malayi hypothetical protein 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Brugia malayi Pre-SET motif family protein 0.0216 0.0758 0.1284
Echinococcus granulosus protein kinase c epsilon type 0.0016 0.0005 0.0007
Brugia malayi EGF-like domain containing protein 0.0029 0.0054 0.0091
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0034 0.0074 0.0101
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Schistosoma mansoni blooms syndrome DNA helicase 0.0038 0.0086 0.011
Brugia malayi Pre-SET motif family protein 0.0032 0.0063 0.0106
Giardia lamblia GTOR 0.0046 0.0119 0.1412
Schistosoma mansoni cation-transporting atpase worm 0.0064 0.0184 0.0235
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0008 0.0013
Leishmania major phospholipid-transporting ATPase 1-like protein 0.0029 0.0052 0.0075
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0029 0.0052 0.008
Mycobacterium tuberculosis Probable reductase 0.0111 0.0365 0.0605
Echinococcus granulosus protein jagged 2 0.0029 0.0054 0.0069
Trichomonas vaginalis MYB3r3, putative 0.0051 0.0137 0.0482
Loa Loa (eye worm) Notch2 0.0029 0.0054 0.0091
Giardia lamblia Cathepsin B precursor 0.0034 0.0074 0.0833
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0119 0.0117
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0069
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0119 0.0179
Echinococcus granulosus phospholipid transporting atpase ih 0.0029 0.0052 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0397 0.0608
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0091 0.0286 0.0366
Onchocerca volvulus 0.0031 0.0059 0.0101
Trypanosoma brucei unspecified product 0.0064 0.0185 0.0281
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Echinococcus multilocularis neurogenic locus notch protein 0.0029 0.0054 0.0069
Trypanosoma brucei DNA polymerase IV, putative 0.012 0.0397 0.0608
Schistosoma mansoni atpase class VI type 11c 0.0041 0.0097 0.0124
Schistosoma mansoni cation-transporting atpase worm 0.0064 0.0184 0.0235
Brugia malayi Associated with TFs and helicases family protein 0.0036 0.0079 0.0133
Toxoplasma gondii cation-transporting atpase family protein 0.0038 0.0086 0.0132
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0031 0.0059 0.0076
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.001
Loa Loa (eye worm) notch protein 0.0029 0.0054 0.0091
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0316 0.1136 0.1917
Toxoplasma gondii P-type ATPase PMA1 0.0124 0.0413 0.0635
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0031 0.0059 0.0076
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0032 0.0063 0.0106
Echinococcus granulosus notch 0.0029 0.0054 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0074 0.0258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0268 0.0454
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.01 0.0322 0.0495
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0084 0.0081
Plasmodium vivax glutathione reductase, putative 0.0049 0.0128 0.0186
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0397 0.0395
Onchocerca volvulus Slit protein homolog 0.0029 0.0054 0.0091
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0064 0.0098
Loa Loa (eye worm) hypothetical protein 0.0039 0.0092 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0074 0.0258
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0034 0.0074 0.0101
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0035 0.005
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0147 0.05 0.0847
Loa Loa (eye worm) hypothetical protein 0.0081 0.025 0.0423
Loa Loa (eye worm) hypothetical protein 0.0129 0.0429 0.0727
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0093 0.0294 0.0375
Echinococcus multilocularis Chromobox protein 3 0.0036 0.0079 0.0101
Echinococcus multilocularis phosphoserine phosphatase 0.0038 0.0086 0.0111
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0044 0.0109 0.0184
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0031 0.0059 0.0076
Brugia malayi Papain family cysteine protease containing protein 0.0098 0.0315 0.0534
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0397 0.0608
Loa Loa (eye worm) transbilayer Amphipath transporters family member 0.0029 0.0052 0.0088
Echinococcus granulosus cathepsin l1 0.0098 0.0315 0.0403
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Brugia malayi glutathione reductase 0.0049 0.0128 0.0217
Echinococcus granulosus cation transporting atpase worm 0.0064 0.0184 0.0235
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0319 0.0487
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0008 0.001
Brugia malayi hypothetical protein 0.002 0.0021 0.0035
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0018 0.001 0.0013
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0086 0.027 0.0458
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0143 0.0216
Trypanosoma brucei phospholipid-translocating P-type ATPase (flippase), putative 0.0029 0.0052 0.0075
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0029 0.0054 0.0069
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0074 0.0094
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0034 0.0074 0.0094
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0091 0.0286 0.0366
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0034 0.0074 0.0833
Brugia malayi Na,K-ATPase alpha subunit 0.0208 0.0729 0.1235
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Trypanosoma cruzi cysteine peptidase, putative 0.0242 0.0857 0.0854
Leishmania major telomerase reverse transcriptase, putative 0.0085 0.0263 0.0401
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0074 0.0255
Brugia malayi E1-E2 ATPase family protein 0.0064 0.0184 0.0312
Loa Loa (eye worm) hypothetical protein 0.0064 0.0184 0.0312
Schistosoma mansoni cathepsin S (C01 family) 0.0034 0.0074 0.0094
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0038 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Echinococcus granulosus dihydrofolate reductase 0.0414 0.1505 0.1924
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0362 0.0462
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0084 0.0124
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0034 0.0074 0.0094
Leishmania major phospholipid-translocating P-type ATPase (flippase), putative 0.0029 0.0052 0.0075
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0083 0.029
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0035 0.005
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0079 0.0109
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0124 0.0412 0.0685
Schistosoma mansoni dihydrofolate reductase 0.0414 0.1505 0.1924
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0041 0.0097 0.0124
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.028 0.1002 0.128
Plasmodium falciparum serine repeat antigen 6 0.0034 0.0074 0.0101
Entamoeba histolytica phospholipid-transporting ATPase IA, putative 0.0029 0.0052 0.0577
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0148 0.0501 0.0767
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0034 0.0074 0.0255
Trichomonas vaginalis chromobox protein, putative 0.01 0.0321 0.1146
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0091 0.0286 0.0366
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Onchocerca volvulus 0.01 0.0321 0.0544
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0268 0.0343
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0189 0.0657 0.0654
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0031 0.0059 0.0101
Trypanosoma brucei calcium-transporting ATPase, putative 0.0029 0.0052 0.0075
Brugia malayi Cathepsin L-like cysteine proteinase 0.0059 0.0167 0.0283
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0018 0.001 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0222 0.0788
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.1737 0.6501 0.65
Trichomonas vaginalis cation-transporting ATPase, putative 0.0026 0.0041 0.0139
Giardia lamblia Cathepsin L precursor 0.0034 0.0074 0.0833
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0085 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0083 0.029
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0069
Brugia malayi Animal haem peroxidase family protein 0.009 0.0284 0.048
Plasmodium vivax unspecified product 0.0034 0.0074 0.0101
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0034 0.0074 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0074 0.0255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0016 0.0006 0.001
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0208 0.0729 0.9142
Echinococcus multilocularis phospholipid transporting ATPase IA 0.0029 0.0052 0.0066
Loa Loa (eye worm) hypothetical protein 0.0036 0.0079 0.0133
Plasmodium falciparum serine repeat antigen 1 0.0034 0.0074 0.0101
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0018 0.001 0.0013
Trichomonas vaginalis hypothetical protein 0.0036 0.0079 0.0274
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0034 0.0074 0.0255
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Echinococcus granulosus cathepsin L 0.0074 0.0222 0.0283
Giardia lamblia Cathepsin L precursor 0.0034 0.0074 0.0833
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0074 0.0094
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0008 0.0008
Brugia malayi hypothetical protein 0.0129 0.043 0.0728
Brugia malayi Cathepsin L-like precursor 0.0039 0.0092 0.0156
Loa Loa (eye worm) hypothetical protein 0.0208 0.0729 0.1235
Plasmodium falciparum cation transporting ATPase, putative 0.0026 0.0041 0.0052
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0296
Onchocerca volvulus 0.01 0.0321 0.0544
Schistosoma mansoni nAChR subunit 0.0031 0.0059 0.0076
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0691 0.2552 0.4322
Echinococcus multilocularis copper transporting ATPase 1 0.0064 0.0184 0.0235
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0074 0.0125
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0035 0.0042
Trypanosoma brucei DNA damage repair protein, putative 0.0029 0.0052 0.0077
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0035 0.155
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0035
Entamoeba histolytica hypothetical protein 0.0036 0.0079 0.0918
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.0079 0.0101
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0036 0.0078 0.012
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0119 0.0152
Giardia lamblia Cysteine protease 0.0034 0.0074 0.0833
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0193 0.0673 0.086
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0031 0.0059 0.0076
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0034 0.0074 0.0125
Brugia malayi EGF-like domain containing protein 0.0029 0.0054 0.0091
Toxoplasma gondii melibiase subfamily protein 0.0106 0.0343 0.0528
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Brugia malayi Bloom's syndrome protein homolog 0.0048 0.0124 0.0209
Leishmania major cysteine peptidase A (CPA) 0.0098 0.0315 0.0481
Plasmodium vivax phospholipid-transporting ATPase, putative 0.0029 0.0052 0.0068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0242 0.0857 0.1314
Onchocerca volvulus 0.002 0.0021 0.0035
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0229 0.0807 0.1032
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0006 0.0005
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0226 0.0797 1
Echinococcus granulosus protein jagged 1 0.0029 0.0054 0.0069
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.01 0.0319 0.0487
Giardia lamblia Encystation-specific protease 0.0034 0.0074 0.0833
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0315 0.1125
Plasmodium vivax vivapain-2 0.0098 0.0315 0.0473
Plasmodium falciparum calcium-transporting ATPase 0.0278 0.0994 0.1519
Echinococcus multilocularis neuropeptide receptor A26 0.0484 0.1773 0.2265
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0074 0.0255
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0138 0.0486
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0031 0.0059 0.0101
Giardia lamblia hypothetical protein 0.0026 0.0041 0.0425
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0143 0.0507
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0031 0.0059 0.0076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0079 0.0274
Plasmodium falciparum serine repeat antigen 2 0.0034 0.0074 0.0101
Trichomonas vaginalis chromobox protein, putative 0.0158 0.054 0.1935
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.017 0.0587 0.075
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0008
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0147 0.05 0.0847
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0052 0.0577
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.004 0.0057
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.001 0.0017
Echinococcus granulosus bloom syndrome protein 0.0048 0.0124 0.0158
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0021 0.0027
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0148 0.0501 0.064
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0074 0.0094
Schistosoma mansoni cathepsin B (C01 family) 0.0034 0.0074 0.0094
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0029 0.0052 0.0177
Echinococcus multilocularis protein jagged 1 0.0029 0.0054 0.0069
Brugia malayi Cytochrome P450 family protein 0.0016 0.0006 0.001
Toxoplasma gondii thioredoxin reductase 0.0049 0.0128 0.0197
Brugia malayi Cytochrome P450 family protein 0.0027 0.0046 0.0078
Onchocerca volvulus 0.0018 0.001 0.0017
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0034 0.0074 0.0101
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0035 0.005
Leishmania major DNA polymerase eta, putative 0.0055 0.0152 0.023
Brugia malayi Niemann-Pick C1 protein precursor 0.0102 0.0328 0.0556
Echinococcus granulosus RUN 0.002 0.0021 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0017
Echinococcus multilocularis musashi 0.0028 0.0049 0.0063
Plasmodium vivax vivapain-1 0.0074 0.0222 0.0329
Toxoplasma gondii cation-transporting ATPase, putative 0.0026 0.0041 0.0063
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0018 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0101
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.058 0.0741
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Onchocerca volvulus 0.0034 0.0074 0.0125
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0109 0.0139
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0031 0.0059 0.0101
Brugia malayi Calcium binding EGF domain containing protein 0.0029 0.0054 0.0091
Schistosoma mansoni DNA polymerase eta 0.0119 0.0393 0.0502
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Brugia malayi fibroinase precursor 0.0034 0.0074 0.0125
Brugia malayi Cadherin domain containing protein 0.0029 0.0054 0.0091
Echinococcus granulosus lamin 0.0028 0.0049 0.0063
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0074 0.0255
Echinococcus granulosus slit 2 protein 0.0029 0.0054 0.0069
Trichomonas vaginalis C-MYB, putative 0.0051 0.0137 0.0482
Mycobacterium tuberculosis Probable oxidoreductase 0.0124 0.0412 0.0685
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0085 0.0296
Echinococcus granulosus Niemann Pick C1 protein 0.0145 0.0493 0.063
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0064 0.0184 0.2232
Loa Loa (eye worm) hypothetical protein 0.0086 0.0268 0.0454
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0093 0.0294 0.0375
Loa Loa (eye worm) hypothetical protein 0.009 0.0284 0.048
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0074 0.0125
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0029 0.0052 0.0177
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.004 0.0037
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0071 0.021 0.0269
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.008 0.0245 0.0414
Entamoeba histolytica cysteine protease, putative 0.0034 0.0074 0.0853
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0175 0.0224
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0018 0.001 0.0013
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0143 0.0183
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0034 0.0074 0.0101
Loa Loa (eye worm) cysteine protease 0.0098 0.0315 0.0534
Trypanosoma cruzi DNA polymerase eta, putative 0.0119 0.0393 0.0391
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0064 0.0184 0.0279
Trichomonas vaginalis DNA helicase recq1, putative 0.0048 0.0124 0.0435
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0006 0.001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0004
Trypanosoma cruzi copper-transporting ATPase, putative 0.0038 0.0086 0.0084
Onchocerca volvulus 0.0018 0.001 0.0017
Onchocerca volvulus 0.009 0.0284 0.048
Loa Loa (eye worm) ACC-1 protein 0.0031 0.0059 0.0101
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0217 0.0765 0.1296
Trypanosoma cruzi cruzipain precursor, putative 0.0242 0.0857 0.0854
Brugia malayi Death domain containing protein 0.0015 0.000000014634 0.000000024786
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0079 0.0274
Plasmodium falciparum serine repeat antigen 7 0.0034 0.0074 0.0101
Onchocerca volvulus 0.0031 0.0059 0.0101
Schistosoma mansoni alpha glucosidase 0.0037 0.0085 0.0109
Plasmodium vivax P-type ATPase4, putative 0.0316 0.1136 0.1738
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0064 0.0184 0.0299
Plasmodium vivax vivapain-3 0.0074 0.0222 0.0329
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0018 0.001 0.005
Schistosoma mansoni nAChR subunit 0.0031 0.0059 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0222 0.0337
Onchocerca volvulus 0.0098 0.0315 0.0534
Echinococcus granulosus Chromo domain 0.0036 0.0079 0.0101
Giardia lamblia DNA damage repair protein 0.0029 0.0052 0.0566
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0018 0.013
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0018 0.001 0.0013
Loa Loa (eye worm) helicase 0.0036 0.0079 0.0133
Giardia lamblia Cathepsin B precursor 0.0034 0.0074 0.0833
Echinococcus multilocularis lamin 0.0028 0.0049 0.0063
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0029 0.0052 0.0177
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0128 0.0126
Echinococcus multilocularis chromobox protein 1 0.0158 0.054 0.069
Loa Loa (eye worm) hypothetical protein 0.0064 0.0184 0.0312
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0094 0.0327
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0397 0.0395
Loa Loa (eye worm) hypothetical protein 0.0098 0.0315 0.0534
Brugia malayi Protein cec-1. 0.0036 0.0079 0.0133
Giardia lamblia Protein tyrosine phosphatase 0.0018 0.001 0.0028
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0315 0.3906
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0064 0.0184 0.2249
Echinococcus granulosus cathepsin b 0.0034 0.0074 0.0094
Schistosoma mansoni phospholipid-transporting atpase 1 (aminophospholipid flippase 1) 0.0026 0.0041 0.0053
Brugia malayi Protein-tyrosine phosphatase 1 0.0018 0.001 0.0017
Schistosoma mansoni pcd6 interacting protein-related 0.0018 0.001 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0074 0.0258
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0006 0.0003
Schistosoma mansoni hypothetical protein 0.0111 0.0362 0.0462
Entamoeba histolytica cysteine proteinase, putative 0.0074 0.0222 0.2725
Loa Loa (eye worm) hypothetical protein 0.0169 0.058 0.0983
Echinococcus multilocularis neurogenic locus notch protein 4 0.0029 0.0054 0.0069
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0036 0.0079 0.0133
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0016 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0162
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.008 0.0245 0.0313
Echinococcus granulosus intermediate filament protein 0.0028 0.0049 0.0063
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0094 0.0298 0.0504
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0056 0.0072
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0138 0.0201
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Echinococcus multilocularis cathepsin L cysteine protease 0.0098 0.0315 0.0403
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0091
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.004 0.0057
Echinococcus multilocularis microtubule associated protein 2 0.2088 0.7825 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0059 0.0101
Echinococcus multilocularis fat cadherin tumor suppressor 0.0029 0.0054 0.0069
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0051 0.0137 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0058 0.0198
Toxoplasma gondii cathepsin CPC1 0.0034 0.0074 0.0112
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0021 0.002
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0034 0.0074 0.0853
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0031 0.0059 0.0076
Trypanosoma brucei phospholipid-translocating ATPase, putative 0.0029 0.0052 0.0075
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0036 0.0079 0.0109
Entamoeba histolytica cysteine protease, putative 0.0074 0.0222 0.2725
Giardia lamblia Hypothetical protein 0.0034 0.0074 0.0833
Echinococcus multilocularis Ankyrin 0.0015 0 0.0001
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0074 0.0125
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0154 0.0197
Echinococcus granulosus tumor protein p63 0.0349 0.1262 0.1613
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Schistosoma mansoni survival motor neuron protein 0.005 0.0132 0.0169
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Onchocerca volvulus 0.009 0.0284 0.048
Plasmodium falciparum guanylyl cyclase 0.0026 0.0041 0.0052
Entamoeba histolytica recQ family helicase, putative 0.0025 0.004 0.0427
Onchocerca volvulus 0.0098 0.0315 0.0534
Brugia malayi polk-prov protein 0.0056 0.0156 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0156 0.0236
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0008 0.0005
Trypanosoma cruzi cysteine proteinase, putative 0.0074 0.0222 0.0219
Leishmania major P-type ATPase, putative 0.0193 0.0673 0.1031
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.001 0.0017
Echinococcus granulosus chromobox protein 1 0.0158 0.054 0.069
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0031 0.0059 0.0076
Echinococcus multilocularis phosphoserine phosphatase 0.0038 0.0086 0.0111
Schistosoma mansoni peroxidasin 0.009 0.0284 0.0362
Schistosoma mansoni nAChR subunit 0.0031 0.0059 0.0076
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0074 0.0222 0.0219
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0154 0.0197
Plasmodium vivax heterochromatin protein 1, putative 0.0036 0.0079 0.0109
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0091 0.0286 0.3528
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0031 0.0059 0.0076
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0029 0.0052 0.0557
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0205 0.0719 0.1209
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0414 0.1505 0.254
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0008 0.001
Echinococcus multilocularis dna polymerase kappa 0.012 0.0397 0.0508
Onchocerca volvulus 0.0018 0.001 0.0017

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4.604 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.133 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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