Detailed information for compound 1592332

Basic information

Technical information
  • TDR Targets ID: 1592332
  • Name: 2-(3-hydroxy-1-adamantyl)acetic acid
  • MW: 210.27 | Formula: C12H18O3
  • H donors: 2 H acceptors: 3 LogP: 1.57 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CC12CC3CC(C1)CC(C2)(C3)O
  • InChi: 1S/C12H18O3/c13-10(14)6-11-2-8-1-9(3-11)5-12(15,4-8)7-11/h8-9,15H,1-7H2,(H,13,14)
  • InChiKey: JFMDWSCOQLUOCZ-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(3-hydroxy-1-adamantyl)ethanoic acid
  • BAS 10152803
  • 1-Hydroxy-3-adamantaneacetic acid
  • 3-Hydroxy-1-(carboxymethyl)adamantane
  • 3-Hydroxy-1-adamantaneacetic acid
  • Tricyclo[3.3.1.13,7]decane-1-acetic acid, 3-hydroxy-
  • (3-Hydroxy-adamantan-1-yl)-acetic acid
  • ST5202974
  • Enamine_000851
  • 1-Adamantaneacetic acid, 3-hydroxy-
  • NSC252898
  • 3-Hydroxytricyclo[3.3.1.13,7]decane-1-acetic acid
  • 678651_ALDRICH
  • (3-hydroxy-1-adamantyl)acetic acid
  • Oprea1_388510
  • 3-Hydroxyadamantane-1-acetic acid
  • FS011397
  • Oprea1_592442
  • SDCCGMLS-0064531.P001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0057 0.0217
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0317 0.1269
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0226 0.0386
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0031 0.0029
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0024 0.0031 0.005
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0615 0.2473 0.4259
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0017 0.0032
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0024 0.0031 0.005
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0024 0.0034 0.0004
Loa Loa (eye worm) TK/ALK protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni hypothetical protein 0.0029 0.0052 0.0085
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1188 0.4799
Onchocerca volvulus 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Entamoeba histolytica glycogen phosphorylase, putative 0.013 0.0472 0.1054
Echinococcus granulosus SHC transforming protein 3 0.0455 0.1815 0.3125
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0455 0.1815 0.3125
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0455 0.1815 0.3125
Loa Loa (eye worm) TK/FER protein kinase 0.0615 0.2473 0.5676
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0072 0.0157
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0024 0.0031 0.005
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0086 0.0084
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0106 0.0104
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0106 0.0296
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0057 0.0217
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0615 0.2473 0.4259
Echinococcus multilocularis tyrosine protein kinase ABL1 0.107 0.4354 0.4353
Schistosoma mansoni phosphatidylserine receptor 0.0024 0.0034 0.0056
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0064 0.0062
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0226 0.0519
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0209 0.0357
Schistosoma mansoni vav2 0.0455 0.1815 0.3125
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0293 0.1172
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0615 0.2473 0.5676
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0135 0.031
Brugia malayi follicle stimulating hormone receptor 0.0024 0.0031 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0064 0.0148
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0615 0.2473 0.4259
Schistosoma mansoni jumonji domain containing protein 0.0024 0.0034 0.0056
Trichomonas vaginalis glycogen phosphorylase, putative 0.013 0.0472 0.1899
Loa Loa (eye worm) hypothetical protein 0.0071 0.0226 0.0514
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0135 0.049
Echinococcus granulosus insulin receptor 0.0615 0.2473 0.4259
Echinococcus multilocularis tyrosine protein kinase csk 0.0615 0.2473 0.2471
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0615 0.2473 0.4259
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0106 0.037
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0064 0.0148
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0135 0.031
Mycobacterium tuberculosis Conserved protein 0.0071 0.0226 0.087
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0136 0.0422
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus jumonji domain containing protein 0.004 0.0098 0.0165
Brugia malayi ORL1-like opioid receptor 0.0024 0.0031 0.0072
Loa Loa (eye worm) hypothetical protein 0.0069 0.0219 0.0497
Mycobacterium tuberculosis Conserved protein 0.0071 0.0226 0.087
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0086 0.0337
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0031 0.005
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0056 0.0166 0.0523
Schistosoma mansoni opsin-like receptor 0.0024 0.0031 0.005
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0072 0.0233
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0086 0.0145
Echinococcus multilocularis integrin linked protein kinase 0.0615 0.2473 0.2471
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0072 0.0157
Echinococcus multilocularis p2X purinoceptor 4 0.0066 0.0204 0.0202
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0002 0.0006
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0136 0.054
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0106 0.0999
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0106 0.021
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0226 0.0903
Entamoeba histolytica tyrosin kinase, putative 0.0615 0.2473 0.5664
Loa Loa (eye worm) TK/FER protein kinase 0.107 0.4354 1
Schistosoma mansoni biogenic amine receptor 0.0024 0.0031 0.005
Brugia malayi beta-lactamase family protein 0.0071 0.0226 0.0519
Brugia malayi Bromodomain containing protein 0.0041 0.0104 0.0239
Onchocerca volvulus 0.107 0.4354 1
Loa Loa (eye worm) TK protein kinase 0.107 0.4354 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0087 0.0293 0.0291
Echinococcus granulosus tyrosine protein kinase 0.0615 0.2473 0.4259
Echinococcus granulosus chromobox protein 1 0.0067 0.0211 0.0361
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.0113
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.003 0.0057 0.0097
Brugia malayi RNA, U transporter 1 0.0069 0.0218 0.0501
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0072 0.012
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Brugia malayi Dopamine receptor 0.0024 0.0031 0.0072
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0136 0.0232
Onchocerca volvulus 0.0615 0.2473 0.5669
Brugia malayi Protein kinase domain containing protein 0.107 0.4354 1
Schistosoma mansoni opsin-like receptor 0.0024 0.0031 0.005
Echinococcus multilocularis NCK adaptor protein 0.0455 0.1815 0.1813
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0013 0.0029
Brugia malayi PHD-finger family protein 0.003 0.0056 0.0129
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Schistosoma mansoni neuropeptide receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0031 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Brugia malayi jmjC domain containing protein 0.0024 0.0034 0.0079
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0167 0.0623 0.1426
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0031 0.005
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0037 0.0012
Echinococcus granulosus expressed conserved protein 0.0455 0.1815 0.3125
Echinococcus multilocularis natriuretic peptide receptor 1 0.0615 0.2473 0.2471
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.0317 0.0707
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0064 0.0148
Loa Loa (eye worm) TK/FER protein kinase 0.107 0.4354 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0455 0.1815 0.4165
Brugia malayi Protein kinase domain containing protein 0.107 0.4354 1
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0031 0.005
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0455 0.1815 0.4168
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0084 0.0558
Schistosoma mansoni histamine h1 receptor 0.0024 0.0031 0.005
Echinococcus granulosus retinal guanylyl cyclase 2 0.0615 0.2473 0.4259
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0226 0.0903
Echinococcus granulosus cpg binding protein 0.0029 0.0055 0.009
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0064 0.0107
Echinococcus multilocularis c src tyrosine kinase 0.107 0.4354 0.4353
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0455 0.1815 0.1813
Schistosoma mansoni tensin 0.0455 0.1815 0.3125
Echinococcus multilocularis Niemann Pick C1 protein 0.029 0.113 0.1128
Onchocerca volvulus 0.0615 0.2473 0.5669
Echinococcus granulosus suppressor of cytokine signaling 6 0.0455 0.1815 0.3125
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0095 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0615 0.2473 0.4259
Echinococcus multilocularis growth factor receptor bound protein 2 0.0455 0.1815 0.1813
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1188 0.4799
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0057 0.0217
Onchocerca volvulus 0.0615 0.2473 0.5669
Echinococcus granulosus tyrosine protein kinase HCK 0.0615 0.2473 0.4259
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0209 0.0357
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0071 0.0226 0.0514
Echinococcus multilocularis neuropeptide receptor A26 0.0024 0.0031 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Schistosoma mansoni hypothetical protein 0.0615 0.2473 0.4259
Echinococcus granulosus tyrosine protein kinase shark 0.107 0.4354 0.7503
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0031 0.0029
Brugia malayi Sex muscle abnormal protein 5 0.0455 0.1815 0.4168
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0031 0.0029
Schistosoma mansoni hypothetical protein 0.0084 0.028 0.0479
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.0317 0.0542
Echinococcus granulosus alpha 1A adrenergic receptor 0.0024 0.0031 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0087 0.0293 0.0667
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Schistosoma mansoni amine GPCR 0.0024 0.0031 0.005
Echinococcus multilocularis nibrin 0.003 0.0057 0.0055
Echinococcus granulosus 7tm_1 domain containing protein 0.0024 0.0031 0.005
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0086 0.0337
Brugia malayi neuropeptide F receptor 0.0024 0.0031 0.0072
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Leishmania major hypothetical protein, conserved 0.0025 0.0037 0.0089
Brugia malayi intermediate filament protein 0.0028 0.0047 0.0109
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0084 0.0207
Schistosoma mansoni alpha-1 adrenergic receptor 0.0024 0.0031 0.005
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0138 0.0505 0.0867
Echinococcus granulosus retinal guanylyl cyclase 2 0.0615 0.2473 0.4259
Brugia malayi larval opioid receptor 0.0024 0.0031 0.0072
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0034 0.0081
Loa Loa (eye worm) hypothetical protein 0.0107 0.0374 0.0853
Brugia malayi jmjC domain containing protein 0.0095 0.0326 0.075
Echinococcus granulosus receptor type guanylyl cyclase 0.0615 0.2473 0.4259
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0031 0.005
Echinococcus granulosus hypothetical protein 0.0455 0.1815 0.3125
Schistosoma mansoni neuropeptide f receptor 76f 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus neuropeptide receptor 0.0024 0.0031 0.005
Mycobacterium ulcerans hypothetical protein 0.0071 0.0226 0.3461
Brugia malayi G-protein coupled receptor 0.0024 0.0031 0.0072
Loa Loa (eye worm) hypothetical protein 0.0071 0.0226 0.0514
Echinococcus granulosus activated cdc42 kinase 1 0.0615 0.2473 0.4259
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0455 0.1815 0.1813
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Brugia malayi Furin-like cysteine rich region family protein 0.0615 0.2473 0.5679
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Echinococcus multilocularis phd:f box containing protein 0.0024 0.0034 0.0032
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0064 0.0107
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0086 0.0337
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0098 0.0096
Loa Loa (eye worm) hypothetical protein 0.0064 0.0199 0.0452
Schistosoma mansoni signal transduction protein lnk-related 0.0455 0.1815 0.3125
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0317 0.1228
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0226 0.3461
Brugia malayi nuclear receptor NHR-88 0.0032 0.0064 0.0148
Trichomonas vaginalis importin beta-1, putative 0.002 0.0015 0.0046
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0106 0.0295
Loa Loa (eye worm) CXXC zinc finger family protein 0.0026 0.0041 0.0088
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0031 0.0029
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0031 0.005
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0095 0.016
Echinococcus granulosus SH2 domain containing protein 7 0.0455 0.1815 0.3125
Giardia lamblia Kinase, NEK 0.0615 0.2473 1
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Echinococcus multilocularis FL cytokine receptor 0.0615 0.2473 0.2471
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0136 0.0422
Onchocerca volvulus 0.0024 0.0031 0.005
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0031 0.005
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0031 0.005
Brugia malayi Heterochromatin protein 1 0.0067 0.0211 0.0486
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0031 0.005
Schistosoma mansoni ets-related 0.0199 0.0755 0.1298
Onchocerca volvulus 0.003 0.0057 0.0108
Echinococcus granulosus 7TM GPCR rhodopsin 0.0024 0.0031 0.005
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0615 0.2473 0.2471
Entamoeba histolytica glycogen phosphorylase, putative 0.0056 0.0166 0.035
Echinococcus multilocularis raf serine:threonine protein kinase 0.0615 0.2473 0.2471
Echinococcus multilocularis tyrosine protein kinase Src42A 0.107 0.4354 0.4353
Brugia malayi Variant SH3 domain containing protein 0.0455 0.1815 0.4168
Mycobacterium ulcerans lipase LipD 0.0071 0.0226 0.3461
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0125
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0136 0.0422
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0056 0.0166 0.2238
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Trichomonas vaginalis TK family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis chromobox protein 1 0.0067 0.0211 0.0209
Brugia malayi putative neuropeptide receptor NPR1 0.0024 0.0031 0.0072
Onchocerca volvulus 0.0615 0.2473 0.5669
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0002 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0064 0.0107
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0002 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0209 0.0357
Echinococcus multilocularis protein patched 0.0087 0.0293 0.0291
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus tyrosine protein kinase csk 0.0615 0.2473 0.4259
Echinococcus granulosus Glycosyl transferase family 35 0.013 0.0472 0.081
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0615 0.2473 0.4259
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0455 0.1815 0.3125
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0024 0.0031 0.005
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0024 0.0034 0.0004
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0086 0.0337
Onchocerca volvulus 0.043 0.1712 0.3918
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0615 0.2473 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0453 0.1804 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0024 0.0031 0.0066
Echinococcus granulosus orexin receptor type 2 0.0024 0.0031 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0615 0.2474 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0615 0.2473 0.2471
Echinococcus granulosus p2X purinoceptor 4 0.0066 0.0204 0.0348
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0064 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Brugia malayi hypothetical protein 0.043 0.1712 0.3931
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0615 0.2473 0.2471
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0064 0.0142
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0226 0.0386
Trichomonas vaginalis replication factor C large subunit, putative 0.003 0.0057 0.0217
Trichomonas vaginalis CAMK family protein kinase 0.0615 0.2473 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.107 0.4354 1
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Toxoplasma gondii STE kinase 0.0615 0.2473 0.9995
Brugia malayi hypothetical protein 0.0024 0.0031 0.0072
Echinococcus multilocularis thyroid hormone receptor alpha 0.017 0.0636 0.0634
Schistosoma mansoni neuropeptide receptor 0.0024 0.0031 0.005
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0064 0.0107
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Brugia malayi Protein kinase domain containing protein 0.107 0.4354 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0024 0.0031 0.005
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0615 0.2473 0.5669
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0064 0.0062
Trypanosoma brucei glucosidase, putative 0.0037 0.0086 0.0216
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Plasmodium falciparum phd finger protein, putative 0.0029 0.0052 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0123 0.0486
Loa Loa (eye worm) hypothetical protein 0.0047 0.0128 0.0288
Loa Loa (eye worm) hypothetical protein 0.043 0.1712 0.3927
Schistosoma mansoni alpha glucosidase 0.0037 0.0086 0.0145
Echinococcus multilocularis tyrosine kinase 0.0615 0.2473 0.2471
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0213 0.0211
Schistosoma mansoni cpg binding protein 0.0029 0.0055 0.009
Schistosoma mansoni tar DNA-binding protein 0.013 0.0472 0.081
Loa Loa (eye worm) TK/FER protein kinase 0.107 0.4354 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0084 0.0658
Entamoeba histolytica serine/threonine kinase, putative 0.0615 0.2473 0.5664
Brugia malayi RE15519p 0.0024 0.0031 0.0072
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Echinococcus granulosus c src tyrosine kinase 0.107 0.4354 0.7503
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Plasmodium falciparum protein kinase, putative 0.0615 0.2473 0.9995
Giardia lamblia Protein 21.1 0.0615 0.2473 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0136 0.054
Loa Loa (eye worm) hypothetical protein 0.0056 0.0165 0.0373
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0125
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0206 0.0784 0.1347
Echinococcus granulosus neuropeptide receptor A26 0.0024 0.0031 0.005
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0064 0.0107
Loa Loa (eye worm) acetyltransferase 0.0162 0.0601 0.1376
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0072 0.0157
Schistosoma mansoni protein kinase 0.0615 0.2473 0.4259
Schistosoma mansoni protein kinase 0.0615 0.2473 0.4259
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0615 0.2473 0.5664
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0064 0.0142
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0226 0.087
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0031 0.005
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Schistosoma mansoni hypothetical protein 0.0084 0.028 0.0479
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Schistosoma mansoni P2X receptor subunit 0.0066 0.0204 0.0348
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0052 0.0113
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0064 0.0148
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Echinococcus granulosus tyrosine protein kinase Src64B 0.107 0.4354 0.7503
Plasmodium vivax tyrosine kinase-like protein, putative 0.0615 0.2473 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0086 0.0193
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.0317 0.0696
Echinococcus granulosus chromobox protein 1 0.0067 0.0211 0.0361
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0211 0.048
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0031 0.0029
Leishmania major protein kinase, putative 0.0615 0.2473 0.9995
Brugia malayi Immunoglobulin I-set domain containing protein 0.0615 0.2473 0.5679
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0037 0.0089
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) glycogen phosphorylase 0.013 0.0472 0.1079
Onchocerca volvulus 0.0028 0.0047 0.0087
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0064 0.0062
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0073 0.0122
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0213 0.0806
Echinococcus granulosus tyrosine protein kinase csk 0.0615 0.2473 0.4259
Schistosoma mansoni alpha-glucosidase 0.0144 0.0527 0.0905
Brugia malayi putative neuropeptide receptor 0.0024 0.0031 0.0072
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0072 0.0157
Loa Loa (eye worm) hypothetical protein 0.0038 0.0089 0.0199
Echinococcus multilocularis tyrosine protein kinase csk 0.0615 0.2473 0.2471
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0456 0.1816 0.4152
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Brugia malayi Serotonin receptor 0.0024 0.0031 0.0072
Brugia malayi ecdysteroid receptor 0.0032 0.0064 0.0148
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus N chimaerin 0.0455 0.1815 0.3125
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Echinococcus multilocularis glycogen phosphorylase 0.013 0.0472 0.047
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Brugia malayi Variant SH3 domain containing protein 0.0455 0.1815 0.4168
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Brugia malayi hypothetical protein 0.023 0.0883 0.2027
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0106 0.0295
Trichomonas vaginalis Importin beta-1 subunit, putative 0.002 0.0015 0.0046
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Brugia malayi Immunoglobulin I-set domain containing protein 0.0615 0.2473 0.5679
Trypanosoma cruzi FHA domain containing protein, putative 0.003 0.0057 0.0171
Loa Loa (eye worm) TK/RYK protein kinase 0.0615 0.2473 0.5676
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Brugia malayi beta-lactamase 0.0071 0.0226 0.0519
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0031 0.0029
Echinococcus multilocularis glycogen phosphorylase 0.013 0.0472 0.047
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Brugia malayi GnHR receptor homolog 0.0024 0.0031 0.0072
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0024 0.0031 0.005
Brugia malayi Serotonin receptor 0.0024 0.0031 0.0072
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0101 0.0396
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0101 0.0211
Trichomonas vaginalis Importin beta-1 subunit, putative 0.002 0.0015 0.0046
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.003 0.0057 0.013
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0615 0.2473 0.5669
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0615 0.2473 0.2471
Echinococcus granulosus somatostatin receptor 0.0024 0.0031 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Echinococcus granulosus tachykinin peptides receptor 99D 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Giardia lamblia Fructose-bisphosphate aldolase 0.0304 0.1188 0.4695
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0106 0.037
Giardia lamblia Glycogen phosphorylase 0.013 0.0472 0.1737
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0031 0.005
Echinococcus granulosus zinc finger protein 0.0024 0.0035 0.0056
Mycobacterium ulcerans hypothetical protein 0.0049 0.0135 0.1599
Loa Loa (eye worm) hypothetical protein 0.0027 0.0045 0.0099
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Schistosoma mansoni myosin xvIII 0.0024 0.0031 0.005
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0064 0.0107
Onchocerca volvulus 0.0028 0.0047 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0064 0.0148
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0317 0.1269
Loa Loa (eye worm) TK protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Echinococcus granulosus Protein patched homolog 1 0.0087 0.0293 0.0501
Brugia malayi hypothetical protein 0.003 0.0057 0.013
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.0317 0.0722
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0304 0.1188 0.2704
Echinococcus multilocularis tyrosine protein kinase 0.0615 0.2473 0.2471
Schistosoma mansoni thyroid hormone receptor 0.017 0.0636 0.1093
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0455 0.1815 0.3125
Echinococcus multilocularis lysine specific demethylase 5A 0.0092 0.0313 0.0311
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0235 0.054
Schistosoma mansoni cpg binding protein 0.0026 0.0041 0.0067
Echinococcus multilocularis JmjC domain containing protein 4 0.0024 0.0034 0.0032
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0226 0.0386
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0226 0.3461
Schistosoma mansoni glycogen phosphorylase 0.013 0.0472 0.081
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Schistosoma mansoni SH2A 0.0455 0.1815 0.3125
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0064 0.0148
Brugia malayi AKH receptor 0.0024 0.0031 0.0072
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0031 0.005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1188 0.4799
Echinococcus granulosus tyrosine protein kinase Srms 0.107 0.4354 0.7503
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0064 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0317 0.1269
Onchocerca volvulus 0.003 0.0056 0.0106
Echinococcus granulosus fmrfamide receptor 0.0024 0.0031 0.005
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0084 0.0048
Schistosoma mansoni P2X receptor subunit 0.0066 0.0204 0.0348
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0615 0.2473 0.5676
Leishmania major hypothetical protein, conserved 0.0615 0.2473 0.9995
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0615 0.2474 0.4261
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0052 0.0074
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0615 0.2473 0.5676
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0615 0.2473 1
Onchocerca volvulus 0.0615 0.2473 0.5669
Trichomonas vaginalis conserved hypothetical protein 0.0615 0.2473 1
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0072 0.0233
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0226 0.087
Schistosoma mansoni tyrosine kinase 0.107 0.4354 0.7503
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0103
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0024 0.0031 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis SH2 domain containing protein 7 0.0455 0.1815 0.1813
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.107 0.4354 0.4353
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.107 0.4354 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0064 0.0062
Schistosoma mansoni hypothetical protein 0.0084 0.028 0.0479
Schistosoma mansoni amine GPCR 0.0024 0.0031 0.005
Echinococcus multilocularis N chimaerin 0.0455 0.1815 0.1813
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0203 0.0771 0.1742
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0615 0.2473 0.5679
Schistosoma mansoni zinc finger protein 0.0024 0.0035 0.0056
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1188 0.4799
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0615 0.2473 0.5679
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0057 0.0217
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0086 0.0337
Loa Loa (eye worm) hypothetical protein 0.0044 0.0114 0.0256
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0072 0.0233
Loa Loa (eye worm) TK/ABL protein kinase 0.107 0.4354 1
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0455 0.1815 0.1813
Brugia malayi sulfakinin receptor protein 0.0024 0.0031 0.0072
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Echinococcus multilocularis tyrosine protein kinase csk 0.0615 0.2473 0.2471
Leishmania major hypothetical protein, conserved 0.0024 0.0034 0.0081
Loa Loa (eye worm) hypothetical protein 0.0049 0.0135 0.0304
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0317 0.0542
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0031 0.0029
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0073 0.0162
Echinococcus granulosus lamin 0.0028 0.0047 0.0078
Onchocerca volvulus 0.0047 0.0127 0.027
Loa Loa (eye worm) hypothetical protein 0.0049 0.0135 0.0304
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0064 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0615 0.2473 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0031 0.005
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.107 0.4354 0.4353
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0064 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Loa Loa (eye worm) TK protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni hypothetical protein 0.0165 0.0614 0.1054
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0209 0.3113
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0037 0.0089
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0226 0.0903
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0064 0.0142
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0148 0.0546 0.2723
Loa Loa (eye worm) TK/FER protein kinase 0.0615 0.2473 0.5676
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0127 0.0292
Echinococcus multilocularis SHC transforming protein 3 0.0455 0.1815 0.1813
Brugia malayi SH2 domain containing protein 0.107 0.4354 1
Entamoeba histolytica protein kinase, putative 0.0456 0.1816 0.4152
Plasmodium falciparum JmjC domain-containing protein, putative 0.0024 0.0034 0.0004
Giardia lamblia Kinase 0.0615 0.2473 1
Schistosoma mansoni ap endonuclease 0.0042 0.0106 0.0178
Echinococcus granulosus growth factor receptor bound protein 2 0.0455 0.1815 0.3125
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0106 0.0415
Brugia malayi Ets-domain containing protein 0.0066 0.0204 0.0469
Echinococcus multilocularis p2X purinoceptor 4 0.0066 0.0204 0.0202
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0064 0.0107
Echinococcus multilocularis tyrosine protein kinase Blk 0.107 0.4354 0.4353
Brugia malayi Dopamine receptor protein 1 0.0024 0.0031 0.0072
Schistosoma mansoni tensin 0.0455 0.1815 0.3125
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0209 0.0207
Loa Loa (eye worm) runx1 0.0054 0.0156 0.0354
Schistosoma mansoni tyrosine kinase 0.107 0.4354 0.7503
Brugia malayi RNA binding protein 0.013 0.0472 0.1084
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.0883 0.0881
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0086 0.0292
Trypanosoma brucei Pseudokinase, putative 0.0615 0.2473 0.9995
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0089 0.0348
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0304 0.1188 0.2704
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Schistosoma mansoni suppressor of cytokine signaling 0.0455 0.1815 0.3125
Echinococcus multilocularis tyrosine protein kinase HCK 0.0615 0.2473 0.2471
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Echinococcus granulosus p2X purinoceptor 4 0.0066 0.0204 0.0348
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0037 0.0012
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.0317 0.0727
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0064 0.0148
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.003 0.0057 0.0095
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0455 0.1815 0.4165
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0615 0.2473 0.2471
Schistosoma mansoni shc transforming protein 0.0455 0.1815 0.3125
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0209 0.072
Schistosoma mansoni serine/threonine protein kinase 0.0615 0.2473 0.4259
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0213 0.0363
Echinococcus granulosus replication factor c subunit 1 0.003 0.0057 0.0094
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0125
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0005
Schistosoma mansoni intermediate filament proteins 0.0028 0.0047 0.0078
Echinococcus granulosus tyrosine protein kinase Lyn 0.107 0.4356 0.7505
Schistosoma mansoni thyroid hormone receptor 0.017 0.0636 0.1093
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0106 0.0173
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0615 0.2473 0.5676
Loa Loa (eye worm) hypothetical protein 0.0203 0.0771 0.1765
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Brugia malayi chromobox protein homolog 3 0.0038 0.0089 0.0205
Schistosoma mansoni biogenic amine receptor 0.0024 0.0031 0.005
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0615 0.2473 0.9995
Onchocerca volvulus 0.0024 0.0031 0.005
Echinococcus multilocularis tyrosine protein kinase pr2 0.0615 0.2473 0.2471
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0024 0.0031 0.0029
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Loa Loa (eye worm) TK protein kinase 0.0615 0.2473 0.5676
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0107 0.0375 0.0855
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0209 0.3113
Brugia malayi Pax transcription activation domain interacting protein 0.003 0.0057 0.013
Echinococcus granulosus serotonin receptor 0.0024 0.0031 0.005
Echinococcus multilocularis tyrosine protein kinase Src64B 0.107 0.4354 0.4353
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0615 0.2473 0.2471
Brugia malayi hypothetical protein 0.0024 0.0031 0.0072
Schistosoma mansoni protein kinase 0.0615 0.2473 0.4259
Plasmodium vivax tyrosine kinase-like protein, putative 0.0615 0.2473 1
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Schistosoma mansoni coup transcription factor 0.0032 0.0064 0.0107
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0615 0.2473 0.4259
Schistosoma mansoni hypothetical protein 0.0455 0.1815 0.3125
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0178 0.0402
Loa Loa (eye worm) hypothetical protein 0.107 0.4354 1
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0317 0.1269
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Echinococcus granulosus fibroblast growth factor receptor 4 0.0615 0.2473 0.4259
Loa Loa (eye worm) hypothetical protein 0.0049 0.0135 0.0304
Echinococcus granulosus tyrosine protein kinase Src42A 0.107 0.4354 0.7503
Onchocerca volvulus 0.0455 0.1815 0.4156
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0211 0.0843
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0073 0.0168
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0314 0.0312
Schistosoma mansoni cpg binding protein 0.0029 0.0055 0.009
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0024 0.0031 0.005
Echinococcus granulosus g protein coupled receptor 0.0024 0.0031 0.005
Onchocerca volvulus 0.107 0.4354 1
Plasmodium falciparum tyrosine kinase-like protein 0.0615 0.2473 0.9995
Echinococcus multilocularis neuropeptide FF receptor 2 0.0024 0.0031 0.0029
Onchocerca volvulus 0.0032 0.0064 0.0126
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0615 0.2473 0.5664
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0135 0.1599
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Brugia malayi hypothetical protein 0.0024 0.0031 0.0072
Echinococcus multilocularis signal transduction protein lnk realted 0.0455 0.1815 0.1813
Plasmodium vivax protein kinase, putative 0.0615 0.2473 1
Plasmodium falciparum replication factor C subunit 1, putative 0.003 0.0057 0.0095
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Schistosoma mansoni serine/threonine RGC 0.0615 0.2473 0.4259
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0031 0.005
Giardia lamblia Kinase, PLK 0.0093 0.0317 0.1095
Brugia malayi hypothetical protein 0.003 0.0057 0.013
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0024 0.0031 0.005
Loa Loa (eye worm) RGC/RGC protein kinase 0.0615 0.2473 0.5676
Brugia malayi hypothetical protein 0.107 0.4354 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0064 0.0142
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0089 0.0183
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0226 0.086
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0135 0.1599
Echinococcus granulosus protein tyrosine kinase 0.0615 0.2473 0.4259
Loa Loa (eye worm) TK/EGFR protein kinase 0.0615 0.2473 0.5676
Trichomonas vaginalis AGC family protein kinase 0.0615 0.2473 1
Leishmania major protein kinase, putative 0.0615 0.2474 1
Echinococcus multilocularis p2X purinoceptor 4 0.0066 0.0204 0.0202
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0057 0.0171
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Schistosoma mansoni importin beta-1 0.0024 0.0034 0.0054
Echinococcus granulosus jumonji domain containing 1A 0.0024 0.0034 0.0056
Echinococcus granulosus neuropeptide s receptor 0.0024 0.0031 0.005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0031 0.0029
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Onchocerca volvulus 0.0024 0.0031 0.005
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0135 0.0343
Echinococcus multilocularis tyrosine kinase 0.107 0.4354 0.4353
Echinococcus multilocularis peregrin 0.0035 0.0077 0.0075
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0213 0.0483
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0073 0.0071
Brugia malayi Variant SH3 domain containing protein 0.0455 0.1815 0.4168
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0209 0.0791
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0106 0.0178
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.003 0.0049
Schistosoma mansoni lamin 0.0028 0.0047 0.0078
Echinococcus multilocularis lamin 0.0028 0.0047 0.0045
Trypanosoma brucei Flagellum attachment zone protein 20 0.0615 0.2473 0.9995
Schistosoma mansoni ephrin receptor 0.0615 0.2473 0.4259
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0615 0.2473 0.2471
Trypanosoma cruzi protein kinase, putative 0.0615 0.2473 0.9995
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0615 0.2473 1
Echinococcus granulosus natriuretic peptide receptor 1 0.0615 0.2473 0.4259
Echinococcus granulosus glycogen phosphorylase 0.013 0.0472 0.081
Echinococcus multilocularis receptor type guanylyl cyclase 0.0615 0.2473 0.2471
Trichomonas vaginalis protein kinase atn1, putative 0.0615 0.2473 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0064 0.0148
Entamoeba histolytica glycogen phosphorylase, putative 0.0056 0.0166 0.035
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0057 0.0171
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Onchocerca volvulus 0.0024 0.0031 0.005
Echinococcus multilocularis g-protein coupled receptor 0.0024 0.0031 0.0029
Schistosoma mansoni hypothetical protein 0.0259 0.1003 0.1725
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0031 0.0066
Onchocerca volvulus 0.0071 0.0226 0.0498
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0615 0.2474 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0142
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0024 0.0031 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0615 0.2473 1
Plasmodium vivax replication factor C subunit 1, putative 0.003 0.0057 0.0095
Echinococcus multilocularis GPCR, family 2 0.0034 0.0073 0.0071
Echinococcus multilocularis sex peptide receptor 0.0024 0.0031 0.0029
Loa Loa (eye worm) TK protein kinase 0.0615 0.2473 0.5676
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0064 0.0062
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0314 0.0538
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0052 0.0085
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Echinococcus multilocularis SH2 motif 0.0455 0.1815 0.1813
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Trichomonas vaginalis esterase, putative 0.0071 0.0226 0.0903
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0162 0.0528
Plasmodium falciparum protein kinase, putative 0.0615 0.2473 0.9995
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0196 0.0194
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Plasmodium falciparum tyrosine kinase-like protein 0.0615 0.2473 0.9995
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0031 0.0029
Schistosoma mansoni hypothetical protein 0.0073 0.0235 0.0401
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0037 0.0012
Brugia malayi SH2 domain containing protein 0.0455 0.1815 0.4168
Schistosoma mansoni growth hormone secretagogue receptor 0.0024 0.0031 0.005
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0226 0.087
Onchocerca volvulus 0.0024 0.0031 0.005
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0615 0.2473 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0455 0.1815 0.4165
Trypanosoma cruzi protein kinase, putative 0.0615 0.2473 0.9995
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0135 0.0277
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Schistosoma mansoni jumonji/arid domain-containing protein 0.0095 0.0326 0.0559
Echinococcus multilocularis microtubule associated protein 2 0.1421 0.5803 0.5802
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0086 0.0337
Onchocerca volvulus 0.0615 0.2473 0.5669
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0111 0.0317
Echinococcus multilocularis tar DNA binding protein 0.013 0.0472 0.047
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.0317 0.1228
Schistosoma mansoni lamin 0.0028 0.0047 0.0078
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0064 0.0126
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0024 0.0031 0.0066
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0024 0.0031 0.0029
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.107 0.4354 0.7503
Echinococcus multilocularis heat shock protein 70 0.0615 0.2473 0.2471
Brugia malayi hypothetical protein 0.0024 0.0031 0.0072
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1188 0.4799
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Echinococcus multilocularis SH2 motif 0.0455 0.1815 0.1813
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0084 0.0207
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0138 0.0505 0.0503
Onchocerca volvulus Glycogen phosphorylase homolog 0.013 0.0472 0.1064
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0086 0.0292
Echinococcus multilocularis SH2 motif 0.0455 0.1815 0.1813
Echinococcus multilocularis protein dispatched 1 0.0099 0.0344 0.0341
Schistosoma mansoni chromosome transmission fidelity factor 0.003 0.0057 0.0094
Brugia malayi Glycosyl hydrolases family 31 protein 0.0167 0.0623 0.1431
Echinococcus multilocularis jumonji domain containing 1A 0.0024 0.0034 0.0032
Loa Loa (eye worm) SH2 domain-containing protein 0.0455 0.1815 0.4165
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0314 0.0312
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0031 0.0029
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0615 0.2473 0.4259
Onchocerca volvulus 0.0097 0.0332 0.0743
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0024 0.0031 0.0072
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0615 0.2473 0.5676
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0314 0.0716
Onchocerca volvulus Alhambra homolog 0.0029 0.0052 0.0097
Echinococcus granulosus tyrosine protein kinase Btk29A 0.107 0.4354 0.7503
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Entamoeba histolytica receptor protein kinase, putative 0.0615 0.2473 0.5664
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0615 0.2473 0.4259
Schistosoma mansoni tar DNA-binding protein 0.013 0.0472 0.081
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0052 0.0074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0034 0.0074
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0615 0.2473 0.5679
Schistosoma mansoni tar DNA-binding protein 0.013 0.0472 0.081
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0064 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0044 0.0164
Entamoeba histolytica ankyrin repeat protein 0.0615 0.2473 0.5664
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0211 0.0843
Echinococcus granulosus retinal guanylyl cyclase 2 0.0615 0.2473 0.4259
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0615 0.2473 0.5664
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0064 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Onchocerca volvulus 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Echinococcus granulosus SH2 motif 0.0455 0.1815 0.3125
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0031 0.005
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0031 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0031 0.0029
Schistosoma mansoni protein tyrosine kinase 0.0615 0.2473 0.4259
Entamoeba histolytica ankyrin repeat protein 0.0615 0.2473 0.5664
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Echinococcus granulosus protein kinase 0.0615 0.2473 0.4259
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0024 0.0031 0.005
Echinococcus multilocularis transfer RNA-Thr 0.0615 0.2473 0.2471
Echinococcus granulosus tyrosine protein kinase Fyn 0.107 0.4354 0.7503
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0064 0.0148
Echinococcus granulosus tyrosine protein kinase Fps85D 0.107 0.4354 0.7503
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Onchocerca volvulus 0.0455 0.1815 0.4156
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0226 0.3461
Onchocerca volvulus 0.0024 0.0031 0.005
Brugia malayi hypothetical protein 0.0024 0.0031 0.0072
Onchocerca volvulus 0.0024 0.0031 0.005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) TK/ACK protein kinase 0.0615 0.2473 0.5676
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0125
Brugia malayi Protein kinase domain containing protein 0.107 0.4354 1
Onchocerca volvulus 0.0455 0.1815 0.4156
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0072 0.0159
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0106 0.0243
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0057 0.0217
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0024 0.0031 0.0072
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0064 0.0107
Trichomonas vaginalis glycogen phosphorylase, putative 0.013 0.0472 0.1899
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0064 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0086 0.0292
Brugia malayi hypothetical protein 0.0017 0.0002 0.0006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0031 0.005
Echinococcus multilocularis lamin dm0 0.0028 0.0047 0.0045
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0028 0.0048 0.008
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0615 0.2473 0.9995
Echinococcus granulosus Niemann Pick C1 protein 0.029 0.113 0.1945
Brugia malayi SH2 domain containing protein 0.0455 0.1815 0.4168
Schistosoma mansoni topbp1 0.003 0.0057 0.0094
Onchocerca volvulus 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0226 0.0514
Echinococcus granulosus nibrin 0.003 0.0057 0.0094
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0034 0.0074
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus SH2 domain containing adapter protein F 0.0455 0.1815 0.3125
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Trypanosoma brucei polo-like protein kinase 0.0093 0.0317 0.116
Schistosoma mansoni growth factor receptor-bound protein 0.0455 0.1815 0.3125
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0314 0.0538
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0455 0.1815 0.4165
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0037 0.0012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0004 0.0002
Entamoeba histolytica hypothetical protein, conserved 0.0615 0.2473 0.5664
Onchocerca volvulus Tyrosine kinase homolog 0.0615 0.2473 0.5669
Loa Loa (eye worm) TK protein kinase 0.0615 0.2473 0.5676
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.003 0.0028
Echinococcus granulosus sterol regulatory element binding protein 0.0087 0.0293 0.0501
Brugia malayi neuropeptide F receptor 0.0024 0.0031 0.0072
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0135 0.1599
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.107 0.4354 0.4353
Brugia malayi hypothetical protein 0.0024 0.0031 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Onchocerca volvulus 0.0024 0.0031 0.005
Brugia malayi Ets-domain containing protein 0.0066 0.0204 0.0469
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1188 0.4799
Onchocerca volvulus 0.0071 0.0226 0.0498
Entamoeba histolytica serine/threonine kinase, putative 0.0615 0.2473 0.5664
Schistosoma mansoni hypothetical protein 0.0034 0.0073 0.0122
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0455 0.1815 0.1813
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0135 0.031
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0106 0.0432
Brugia malayi hypothetical protein 0.0615 0.2473 0.5679
Schistosoma mansoni ap endonuclease 0.0042 0.0106 0.0178
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0142
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0072 0.0157
Echinococcus granulosus integrin linked protein kinase 0.0615 0.2473 0.4259
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0031 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0031 0.005
Loa Loa (eye worm) RNA binding protein 0.013 0.0472 0.1079
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0317 0.1269
Toxoplasma gondii protein kinase 0.0615 0.2473 0.9995
Giardia lamblia Kinase, NEK 0.0615 0.2473 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0615 0.2474 1
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Echinococcus multilocularis kinase suppressor of Ras 1 0.0615 0.2473 0.2471
Loa Loa (eye worm) jmjC domain-containing protein 0.0095 0.0326 0.0745
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0024 0.0034 0.0056
Echinococcus multilocularis tyrosine protein kinase Fgr 0.107 0.4354 0.4353
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0135 0.1599
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0213 0.0734
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0064 0.0062
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0064 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0031 0.005
Schistosoma mansoni hypothetical protein 0.0024 0.0031 0.005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0064 0.0148
Brugia malayi Guanylyl cyclase protein 23 0.0615 0.2473 0.5679
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0122
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0213 0.0457
Schistosoma mansoni protein kinase 0.0615 0.2473 0.4259
Schistosoma mansoni protein kinase 0.0615 0.2473 0.4259
Brugia malayi Tachykinin-like peptides receptor 99D 0.0024 0.0031 0.0072
Echinococcus multilocularis ephrin type A receptor 4 A 0.0615 0.2473 0.2471
Echinococcus multilocularis replication factor c subunit 1 0.003 0.0057 0.0055
Echinococcus multilocularis geminin 0.0165 0.0614 0.0612
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0004 0.0004
Echinococcus multilocularis Niemann Pick C1 protein 0.0203 0.0771 0.0769
Onchocerca volvulus 0.0024 0.0031 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Schistosoma mansoni glycogen phosphorylase 0.013 0.0472 0.081
Schistosoma mansoni amine GPCR 0.0024 0.0031 0.005
Brugia malayi G-protein coupled receptor 0.0024 0.0031 0.0072
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0455 0.1815 0.3125
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0125
Brugia malayi SH2 domain containing protein 0.0455 0.1815 0.4168
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0064 0.0148
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.107 0.4354 1
Brugia malayi SH2 domain containing protein 0.0455 0.1815 0.4168
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0101 0.0396
Schistosoma mansoni hypothetical protein 0.0034 0.0073 0.0122
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Schistosoma mansoni protein kinase 0.0615 0.2474 0.4261
Echinococcus multilocularis GA binding protein alpha chain 0.0066 0.0204 0.0202
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0047 0.0103
Mycobacterium tuberculosis Conserved protein 0.0071 0.0226 0.087
Echinococcus granulosus NCK adaptor protein 0.0455 0.1815 0.3125
Brugia malayi steroid hormone receptor 0.0032 0.0064 0.0148
Echinococcus granulosus tyrosine protein kinase Blk 0.107 0.4354 0.7503
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0024 0.0031 0.005
Schistosoma mansoni protein kinase 0.0615 0.2474 0.4261
Loa Loa (eye worm) TK protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0004 0.0004
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Onchocerca volvulus 0.0615 0.2473 0.5669
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0226 0.0789
Entamoeba histolytica tyrosin kinase, putative 0.0615 0.2473 0.5664
Loa Loa (eye worm) fli-1 protein 0.0199 0.0755 0.173
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.0623 0.0621
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0615 0.2473 0.4259
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0031 0.005
Echinococcus granulosus tensin 0.0455 0.1815 0.3125
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0086 0.0165
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0455 0.1815 0.3125
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0004 0.0004
Schistosoma mansoni adapter molecule crk 0.0455 0.1815 0.3125
Schistosoma mansoni patched 1 0.0087 0.0293 0.0501
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0226 0.086
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0064 0.0148
Loa Loa (eye worm) TK/FER protein kinase 0.107 0.4354 1
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0037 0.0012
Echinococcus multilocularis chromobox protein 1 0.0067 0.0211 0.0209
Brugia malayi C-terminal src kinase protein 1 0.0615 0.2473 0.5679
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0031 0.005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Loa Loa (eye worm) beta-lactamase 0.0071 0.0226 0.0514
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0123 0.0486
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0086 0.0337
Echinococcus granulosus lysosomal alpha glucosidase 0.0167 0.0623 0.107
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0615 0.2473 0.5679
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0057 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0031 0.005
Echinococcus multilocularis somatostatin receptor 0.0024 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Echinococcus granulosus g protein coupled receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Echinococcus granulosus activated cdc42 kinase 1 0.0615 0.2473 0.4259
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Onchocerca volvulus 0.0071 0.0226 0.0498
Echinococcus multilocularis tensin 0.0455 0.1815 0.1813
Loa Loa (eye worm) SRC-1 0.107 0.4354 1
Schistosoma mansoni alpha-glucosidase 0.0144 0.0527 0.0905
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Mycobacterium ulcerans beta-lactamase 0.0071 0.0226 0.3461
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0213 0.0363
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0455 0.1815 0.3125
Echinococcus granulosus expressed conserved protein 0.019 0.072 0.1237
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0024 0.0031 0.0029
Echinococcus multilocularis insulin receptor 0.0615 0.2473 0.2471
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Schistosoma mansoni hypothetical protein 0.0024 0.0031 0.005
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0031 0.005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1188 0.4799
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0031 0.0029
Echinococcus multilocularis tyrosine protein kinase Srms 0.107 0.4354 0.4353
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Onchocerca volvulus 0.0024 0.0031 0.005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0064 0.0148
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0072 0.007
Loa Loa (eye worm) hypothetical protein 0.023 0.0883 0.2023
Brugia malayi SH2 domain containing protein 0.107 0.4354 1
Loa Loa (eye worm) TYRA-2 protein 0.0024 0.0031 0.0066
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Brugia malayi RNA recognition motif domain containing protein 0.013 0.0472 0.1084
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0064 0.0148
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0021 0.0042
Entamoeba histolytica serine/threonine kinase, putative 0.0615 0.2473 0.5664
Onchocerca volvulus 0.0024 0.0031 0.005
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0024 0.0031 0.0066
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0106 0.0237
Loa Loa (eye worm) TK protein kinase 0.0615 0.2473 0.5676
Loa Loa (eye worm) protein kinase domain-containing protein 0.0615 0.2473 0.5676
Loa Loa (eye worm) TK/FER protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.107 0.4354 0.7503
Onchocerca volvulus 0.0615 0.2473 0.5669
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Schistosoma mansoni hypothetical protein 0.0455 0.1815 0.3125
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0615 0.2473 0.2471
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0024 0.0031 0.0029
Onchocerca volvulus 0.0024 0.0031 0.005
Toxoplasma gondii protein kinase domain-containing protein 0.0615 0.2473 0.9995
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0226 0.087
Brugia malayi jmjC domain containing protein 0.0024 0.0034 0.0079
Echinococcus granulosus sex peptide receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) STAT protein 0.0455 0.1815 0.4165
Echinococcus multilocularis 0.0455 0.1815 0.1813
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0314 0.0538
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1188 0.4799
Loa Loa (eye worm) TK/ROR protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni serine/threonine protein kinase 0.0615 0.2473 0.4259
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0226 0.087
Echinococcus multilocularis cpg binding protein 0.0029 0.0055 0.0052
Schistosoma mansoni protein kinase 0.0615 0.2473 0.4259
Loa Loa (eye worm) TK/EPH protein kinase 0.0615 0.2473 0.5676
Brugia malayi acetyltransferase, GNAT family protein 0.0162 0.0601 0.1381
Brugia malayi hypothetical protein 0.0024 0.0031 0.0072
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0074
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0455 0.1815 0.1813
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0148 0.0546 1
Schistosoma mansoni chromobox protein 0.0067 0.0211 0.0361
Schistosoma mansoni hypothetical protein 0.0024 0.0031 0.005
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Loa Loa (eye worm) TAR-binding protein 0.013 0.0472 0.1079
Loa Loa (eye worm) TK/FER protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni DNA ligase IV 0.003 0.0057 0.0094
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0031 0.005
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0052 0.0074
Echinococcus granulosus tyrosine protein kinase Fyn 0.107 0.4354 0.7503
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Brugia malayi hypothetical protein 0.0017 0.0002 0.0006
Echinococcus multilocularis epidermal growth factor receptor 0.0615 0.2473 0.2471
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0455 0.1815 0.3125
Onchocerca volvulus 0.0024 0.0031 0.005
Brugia malayi G protein-coupled receptor F59B2.13 0.0024 0.0031 0.0072
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0086 0.0198
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0142
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0057 0.0171
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.107 0.4354 0.7503
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Schistosoma mansoni hypothetical protein 0.0165 0.0614 0.1054
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0055 0.0161 0.0274
Echinococcus granulosus survival motor neuron protein 1 0.023 0.0883 0.1518
Loa Loa (eye worm) RGC/RGC protein kinase 0.0615 0.2473 0.5676
Entamoeba histolytica serine/threonine kinase, putative 0.0615 0.2473 0.5664
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0047 0.0109
Entamoeba histolytica glycogen phosphorylase, putative 0.013 0.0472 0.1054
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0052 0.005
Echinococcus granulosus tyrosine kinase 0.107 0.4354 0.7503
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0066 0.0204 0.0463
Toxoplasma gondii exonuclease III APE 0.0042 0.0106 0.0295
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Echinococcus granulosus intermediate filament protein 0.0028 0.0047 0.0078
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0455 0.1815 0.4156
Schistosoma mansoni tensin-related 0.0455 0.1815 0.3125
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Echinococcus granulosus tyrosine protein kinase ABL1 0.107 0.4354 0.7503
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0071
Echinococcus granulosus tyrosine kinase 0.0615 0.2473 0.4259
Brugia malayi PHD-finger family protein 0.0029 0.0052 0.0119
Brugia malayi Raf kinase 0.0615 0.2473 0.5679
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Echinococcus granulosus lysine specific demethylase 6a 0.0024 0.0034 0.0056
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0024 0.0031 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.107 0.4354 0.4353
Onchocerca volvulus 0.0026 0.0041 0.0072
Schistosoma mansoni ephrin receptor 0.0615 0.2473 0.4259
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0615 0.2473 0.5679
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0031 0.0029
Schistosoma mansoni gabp alpha 0.0066 0.0204 0.0348
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0064 0.0107
Echinococcus granulosus G protein coupled receptor 139 0.0024 0.0031 0.005
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0024 0.0034 0.0004
Echinococcus granulosus suppressor of cytokine signaling 7 0.0455 0.1815 0.3125
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0086 0.0337
Echinococcus granulosus raf serine:threonine protein kinase 0.0615 0.2473 0.4259
Schistosoma mansoni hypothetical protein 0.0034 0.0073 0.0122
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0135 0.0277
Echinococcus granulosus glycogen phosphorylase 0.013 0.0472 0.081
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0107 0.0375 0.086
Schistosoma mansoni P2X receptor subunit 0.0066 0.0204 0.0348
Echinococcus granulosus epidermal growth factor receptor 0.0615 0.2473 0.4259
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0057 0.0095
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0064 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0155 0.0573 0.0984
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Echinococcus granulosus SH2 motif 0.0455 0.1815 0.3125
Brugia malayi hypothetical protein 0.0025 0.0037 0.0084
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0086 0.0165
Schistosoma mansoni tar DNA-binding protein 0.013 0.0472 0.081
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Schistosoma mansoni protein phosphatase 2C 0.0024 0.0034 0.0056
Echinococcus granulosus dro:myosuppressin receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0615 0.2473 0.5676
Entamoeba histolytica SH2 domain containing protein 0.0455 0.1815 0.4149
Entamoeba histolytica glycogenphosphorylase, putative 0.0056 0.0166 0.035
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0615 0.2473 0.5676
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0187
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0074
Brugia malayi jmjC domain containing protein 0.0024 0.0034 0.0079
Echinococcus multilocularis neuropeptide s receptor 0.0024 0.0031 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0317 0.1269
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Echinococcus multilocularis expressed conserved protein 0.019 0.072 0.0718
Brugia malayi nuclear hormone receptor 0.0032 0.0064 0.0148
Schistosoma mansoni hypothetical protein 0.0138 0.0505 0.0867
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.003 0.0049
Brugia malayi bone morphogenetic protein type 1 receptor 0.0615 0.2473 0.5679
Brugia malayi cytokine inducible SH2-containing protein 5 0.0455 0.1815 0.4168
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0031 0.005
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Schistosoma mansoni tyrosine kinase 0.107 0.4354 0.7503
Loa Loa (eye worm) SH2 domain-containing protein 0.0455 0.1815 0.4165
Treponema pallidum fructose-bisphosphate aldolase 0.0304 0.1188 1
Schistosoma mansoni kinase 0.0047 0.0128 0.0217
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0317 0.1228
Echinococcus granulosus hypothetical protein 0.0024 0.0031 0.005
Schistosoma mansoni tyrosine kinase 0.107 0.4354 0.7503
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0031 0.0029
Schistosoma mansoni hypothetical protein 0.0034 0.0073 0.0122
Echinococcus multilocularis tyrosine protein kinase csk 0.0615 0.2473 0.2471
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0226 0.079
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0064 0.0142
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0135 0.049
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2474 0.5667
Echinococcus multilocularis activated cdc42 kinase 1 0.0615 0.2473 0.2471
Loa Loa (eye worm) TK/Met protein kinase 0.0615 0.2473 0.5676
Echinococcus multilocularis dro:myosuppressin receptor 0.0024 0.0031 0.0029
Echinococcus granulosus Niemann Pick C1 protein 0.0203 0.0771 0.1325
Loa Loa (eye worm) hypothetical protein 0.0071 0.0226 0.0514
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.107 0.4354 0.4353
Schistosoma mansoni opsin-like receptor 0.0024 0.0031 0.005
Schistosoma mansoni jumonji domain containing protein 0.0132 0.0477 0.0819
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0226 0.087
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0615 0.2473 0.2471
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0615 0.2473 0.4259
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0064 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0615 0.2473 1
Brugia malayi G protein-coupled receptor 0.0024 0.0031 0.0072
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Chlamydia trachomatis glycogen phosphorylase 0.013 0.0472 1
Brugia malayi SH2 domain containing protein 0.0455 0.1815 0.4168
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0024 0.0031 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0031 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0615 0.2473 1
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0162 0.0601 0.0599
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0615 0.2473 0.2471
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0106 0.037
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0135 0.1599
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0031 0.0029
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.107 0.4354 0.4353
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Brugia malayi Importin beta-1 subunit 0.0024 0.0034 0.0077
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Echinococcus granulosus snurportin 1 0.0259 0.1003 0.1725
Schistosoma mansoni hypothetical protein 0.0047 0.0127 0.0215
Echinococcus multilocularis activin receptor type 0.0615 0.2474 0.2472
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0314 0.0538
Schistosoma mansoni protein kinase 0.0615 0.2473 0.4259
Brugia malayi DKFZp564C0469 protein 0.003 0.0057 0.013
Echinococcus granulosus microtubule associated protein 2 0.1421 0.5803 1
Brugia malayi nuclear receptor RXR 0.0017 0.0002 0.0006
Echinococcus multilocularis protein KINase family member (kin 25) 0.0615 0.2473 0.2471
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0142
Echinococcus granulosus signal transduction protein lnk realted 0.0455 0.1815 0.3125
Echinococcus multilocularis importin subunit beta 1 0.0024 0.0034 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0162 0.0601 0.1033
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis Protein lozenge 0.0054 0.0156 0.0154
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0073 0.0162
Onchocerca volvulus 0.107 0.4354 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0024 0.0031 0.0072
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0226 0.087
Entamoeba histolytica hypothetical protein 0.003 0.0057 0.0097
Schistosoma mansoni nck2/grb4 0.0455 0.1815 0.3125
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0031 0.005
Schistosoma mansoni bromodomain containing protein 0.0067 0.0211 0.036
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0031 0.0066
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Brugia malayi carbohydrate phosphorylase 0.013 0.0472 0.1084
Echinococcus multilocularis zinc finger protein 0.0024 0.0035 0.0032
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0615 0.2474 1
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0455 0.1815 0.3125
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0615 0.2473 0.4259
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0024 0.0031 0.0029
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0024 0.0031 0.0029
Schistosoma mansoni GTPase activating protein 0.0455 0.1815 0.3125
Echinococcus granulosus tyrosine protein kinase csk 0.0615 0.2473 0.4259
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0209 0.0772
Echinococcus granulosus p2X purinoceptor 4 0.0066 0.0204 0.0348
Brugia malayi Melatonin receptor type 1A 0.0024 0.0031 0.0072
Brugia malayi Dopamine receptor protein 2 0.0024 0.0031 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.0615 0.2473 0.4259
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0064 0.0107
Brugia malayi integrin-linked kinase 0.0615 0.2473 0.5679
Loa Loa (eye worm) TK/FAK protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0031 0.005
Onchocerca volvulus 0.107 0.4354 1
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Echinococcus multilocularis protein kinase 0.0615 0.2473 0.2471
Schistosoma mansoni neuropeptide receptor 0.0024 0.0031 0.005
Trichomonas vaginalis STE family protein kinase 0.0615 0.2473 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0375 0.0855
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0031 0.0029
Brugia malayi Tyrosine-protein kinase abl-1 0.107 0.4354 1
Brugia malayi RhoGAP domain containing protein 0.0455 0.1815 0.4168
Schistosoma mansoni tensin 0.0455 0.1815 0.3125
Loa Loa (eye worm) hypothetical protein 0.0073 0.0235 0.0534
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0317 0.1269
Echinococcus multilocularis G-protein coupled receptor, putative 0.0024 0.0031 0.0029
Echinococcus multilocularis Glycosyl transferase, family 35 0.013 0.0472 0.047
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0209 0.3113
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0031 0.0029
Onchocerca volvulus 0.0455 0.1815 0.4156
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0073 0.0071
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Entamoeba histolytica tyrosin kinase, putative 0.0615 0.2473 0.5664
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0455 0.1815 0.1813
Brugia malayi hypothetical protein 0.0024 0.0031 0.0072
Schistosoma mansoni neuropeptide receptor 0.0024 0.0031 0.005
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0615 0.2473 0.4259
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0106 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0151 0.0557 0.0555
Schistosoma mansoni glycogen phosphorylase 0.0056 0.0166 0.0283
Loa Loa (eye worm) TK/CSK protein kinase 0.0615 0.2473 0.5676
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0024 0.0031 0.0072
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0615 0.2473 0.9995
Schistosoma mansoni tyrosine kinase 0.107 0.4354 0.7503
Echinococcus granulosus ephrin type A receptor 4 A 0.0615 0.2473 0.4259
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0047 0.0103
Echinococcus granulosus importin subunit beta 1 0.0024 0.0034 0.0054
Loa Loa (eye worm) hypothetical protein 0.0071 0.0226 0.0514
Loa Loa (eye worm) TK/DDR protein kinase 0.0615 0.2473 0.5676
Echinococcus multilocularis serotonin receptor 0.0024 0.0031 0.0029
Onchocerca volvulus 0.0455 0.1815 0.4156
Schistosoma mansoni hypothetical protein 0.0084 0.028 0.0479
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0615 0.2473 0.2471
Trichomonas vaginalis conserved hypothetical protein 0.0615 0.2473 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0187
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0615 0.2473 0.5679
Schistosoma mansoni chromobox protein 0.0067 0.0211 0.0361
Echinococcus granulosus allatostatin A receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0187
Schistosoma mansoni protein kinase 0.0615 0.2473 0.4259
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Loa Loa (eye worm) TK/FER protein kinase 0.107 0.4354 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0031 0.005
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0455 0.1815 0.1813
Brugia malayi hypothetical protein 0.0024 0.0031 0.0072
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0106 0.0415
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0148 0.0546 1
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Brugia malayi TAR-binding protein 0.013 0.0472 0.1084
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) hypothetical protein 0.0025 0.0037 0.0078
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Onchocerca volvulus Neuropeptide F receptor homolog 0.0024 0.0031 0.005
Mycobacterium leprae Probable lipase LipE 0.0071 0.0226 0.3461
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0455 0.1815 0.1813
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0071 0.0226 0.0514
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0615 0.2473 0.4259
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0087 0.0293 0.0667
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0064 0.0107
Leishmania major hypothetical protein, conserved 0.0034 0.0072 0.0233
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Brugia malayi Fli-1 protein 0.0199 0.0755 0.1735
Brugia malayi SH2 domain containing protein 0.0455 0.1815 0.4168
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Brugia malayi Augmenter of liver regeneration 0.0034 0.0072 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0057 0.0217
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0073 0.0122
Echinococcus granulosus lysine specific demethylase 5A 0.0095 0.0326 0.0559
Loa Loa (eye worm) RGC/RGC protein kinase 0.0615 0.2473 0.5676
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0615 0.2473 0.4259
Echinococcus granulosus tyrosine protein kinase Fyn 0.107 0.4354 0.7503
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0064 0.0126
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0615 0.2473 0.2471
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0073 0.0168
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0031 0.0029
Brugia malayi jmjC domain containing protein 0.0024 0.0034 0.0079
Brugia malayi hypothetical protein 0.0455 0.1815 0.4168
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0226 0.0224
Brugia malayi Tyrosine-protein kinase PR2 0.0615 0.2473 0.5679
Entamoeba histolytica tyrosin kinase, putative 0.0615 0.2473 0.5664
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0135 0.1599
Brugia malayi Calcitonin receptor-like protein seb-1 0.0107 0.0375 0.086
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Schistosoma mansoni lozenge 0.0054 0.0156 0.0266
Entamoeba histolytica serine/threonine kinase, putative 0.0615 0.2473 0.5664
Echinococcus multilocularis epidermal growth factor receptor 0.0615 0.2473 0.2471
Brugia malayi Bromodomain containing protein 0.0035 0.0077 0.0178
Echinococcus multilocularis tyrosine protein kinase Fyn 0.107 0.4354 0.4353
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0455 0.1815 0.4156
Leishmania major hypothetical protein, conserved 0.0071 0.0226 0.086
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0615 0.2473 0.4259
Schistosoma mansoni suppressor of cytokine signaling 0.0455 0.1815 0.3125
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0135 0.049
Brugia malayi Variant SH3 domain containing protein 0.0455 0.1815 0.4168
Schistosoma mansoni tar DNA-binding protein 0.013 0.0472 0.081
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0135 0.1599
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0142
Toxoplasma gondii ATPase, AAA family protein 0.003 0.0057 0.0095
Brugia malayi Receptor family ligand binding region containing protein 0.0615 0.2473 0.5679
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0031 0.005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0064 0.0107
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0078 0.0131
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0135 0.0343
Loa Loa (eye worm) RGC/RGC protein kinase 0.0615 0.2473 0.5676
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0259 0.1003 0.2299
Echinococcus multilocularis snurportin 1 0.0259 0.1003 0.1001
Brugia malayi CHE-14 protein 0.0087 0.0293 0.0672
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0455 0.1815 0.3125
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus kinase suppressor of Ras 1 0.0615 0.2473 0.4259
Echinococcus multilocularis musashi 0.0028 0.0047 0.0045
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Brugia malayi Tensin 0.0455 0.1815 0.4168
Schistosoma mansoni adenoreceptor 0.0024 0.0031 0.005
Onchocerca volvulus 0.0615 0.2473 0.5669
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0226 0.0903
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0213 0.0806
Brugia malayi STAT protein, DNA binding domain containing protein 0.0455 0.1815 0.4168
Schistosoma mansoni biogenic amine receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Echinococcus granulosus peptide allatostatin:somatostatin 0.0024 0.0031 0.005
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0031 0.005
Echinococcus granulosus activin receptor type 0.0615 0.2474 0.4261
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0052 0.0085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0031 0.005
Plasmodium vivax JmjC domain containing protein 0.0024 0.0034 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.107 0.4354 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0024 0.0031 0.0029
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0086 0.0337
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0044 0.0164
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0455 0.1815 0.4165
Schistosoma mansoni topbp1 0.003 0.0057 0.0094
Echinococcus multilocularis allatostatin A receptor 0.0024 0.0031 0.0029
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0064 0.0126
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0031 0.005
Echinococcus multilocularis orexin receptor type 2 0.0024 0.0031 0.0029
Echinococcus granulosus g protein coupled receptor 0.0024 0.0031 0.005
Entamoeba histolytica hypothetical protein 0.0615 0.2473 0.5664
Schistosoma mansoni survival motor neuron protein 0.0047 0.0127 0.0215
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0024 0.0034 0.0032
Echinococcus granulosus neuropeptide receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0615 0.2473 0.5676
Schistosoma mansoni tyrosine kinase 0.107 0.4354 0.7503
Echinococcus granulosus peregrin 0.0035 0.0077 0.013
Brugia malayi ephrin receptor 1 precursor 0.0615 0.2473 0.5679
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Entamoeba histolytica cysteine surface protein, putative 0.0615 0.2473 0.5664
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Schistosoma mansoni phd/f-box containing protein 0.0024 0.0034 0.0056
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0615 0.2474 0.2472
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0078 0.0076
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0057 0.0217
Loa Loa (eye worm) hypothetical protein 0.043 0.1712 0.3927
Trichomonas vaginalis protein tyrosine kinase, putative 0.0615 0.2473 1
Giardia lamblia Replication factor C, subunit 1 0.003 0.0057 0.0021
Onchocerca volvulus 0.107 0.4354 1
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0057 0.0217
Onchocerca volvulus 0.0049 0.0135 0.0289
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0064 0.0142
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0213 0.0806
Echinococcus granulosus neuropeptide FF receptor 2 0.0024 0.0031 0.005
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0034 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus epidermal growth factor receptor 0.0615 0.2473 0.4259
Schistosoma mansoni jumonji/arid domain-containing protein 0.0095 0.0326 0.0559
Entamoeba histolytica receptor protein kinase, putative 0.0615 0.2473 0.5664
Trypanosoma brucei protein kinase, putative 0.0615 0.2474 1
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0615 0.2473 0.4259
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0455 0.1815 0.4165
Loa Loa (eye worm) melatonin receptor type 1A 0.0024 0.0031 0.0066
Echinococcus granulosus tar DNA binding protein 0.013 0.0472 0.081
Plasmodium falciparum protein kinase, putative 0.0615 0.2474 1
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Toxoplasma gondii ABC1 family protein 0.0071 0.0226 0.0789
Schistosoma mansoni P2X receptor subunit 0.0066 0.0204 0.0348
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0064 0.0148
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Schistosoma mansoni hypothetical protein 0.0024 0.0031 0.005
Echinococcus multilocularis tyrosine protein kinase Fyn 0.107 0.4354 0.4353
Loa Loa (eye worm) TK/FER protein kinase 0.107 0.4354 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0314 0.0722
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0615 0.2473 0.2471
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0615 0.2473 0.5664
Schistosoma mansoni tensin-related 0.0455 0.1815 0.3125
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Loa Loa (eye worm) hypothetical protein 0.0037 0.0088 0.0197
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Schistosoma mansoni amine GPCR 0.0024 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0455 0.1815 0.4165
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0064 0.0107
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0142
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0031 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0111 0.0222
Brugia malayi hypothetical protein 0.0615 0.2473 0.5679
Brugia malayi Niemann-Pick C1 protein precursor 0.0203 0.0771 0.177
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.107 0.4354 0.4353
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0024 0.0031 0.0066
Schistosoma mansoni hypothetical protein 0.002 0.0017 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0226 0.0903
Echinococcus multilocularis serotonin receptor 0.0024 0.0031 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Echinococcus granulosus tyrosine protein kinase pr2 0.0615 0.2473 0.4259
Echinococcus granulosus phd:f box containing protein 0.0024 0.0034 0.0056
Echinococcus granulosus tyrosine protein kinase Src42A 0.0455 0.1815 0.3125
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0028 0.0048 0.0046
Echinococcus multilocularis protein tyrosine kinase 0.0615 0.2473 0.2471
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0615 0.2473 0.4259
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Echinococcus multilocularis protein kinase 0.0615 0.2473 0.2471
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0034 0.0081
Brugia malayi topoisomerase 0.003 0.0057 0.013
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0135 0.1599
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Schistosoma mansoni protein kinase 0.0615 0.2474 0.4261
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0187
Brugia malayi Protein kinase domain containing protein 0.107 0.4354 1
Brugia malayi jmjC domain containing protein 0.0151 0.0557 0.1279
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0031 0.005
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Schistosoma mansoni tyrosine protein kinase 0.0615 0.2473 0.4259
Brugia malayi hypothetical protein 0.0024 0.0031 0.0072
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.0317 0.0315
Echinococcus multilocularis tyrosine protein kinase shark 0.107 0.4354 0.4353
Brugia malayi protein-tyrosine kinase 0.107 0.4354 1
Loa Loa (eye worm) TK/FER protein kinase 0.107 0.4354 1
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0064 0.0107
Echinococcus granulosus g-protein coupled receptor 0.0024 0.0031 0.005
Loa Loa (eye worm) serine/threonine protein kinase 0.0615 0.2473 0.5676
Echinococcus multilocularis G protein coupled receptor 139 0.0024 0.0031 0.0029
Onchocerca volvulus 0.107 0.4354 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0151 0.0557 0.0956
Schistosoma mansoni serine/threonine protein kinase 0.0615 0.2473 0.4259
Brugia malayi SRC-1 0.107 0.4354 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0314 0.0538
Loa Loa (eye worm) TK/INSR protein kinase 0.0615 0.2473 0.5676
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0196 0.0335
Brugia malayi Bromodomain containing protein 0.0079 0.0258 0.0593
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Echinococcus granulosus JmjC domain containing protein 4 0.0024 0.0034 0.0056
Echinococcus granulosus GA binding protein alpha chain 0.0066 0.0204 0.0348
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0066
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0213 0.0489
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0135 0.1599
Brugia malayi beta-lactamase family protein 0.0071 0.0226 0.0519
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0002 0.0001
Loa Loa (eye worm) SH2 domain-containing protein 0.0455 0.1815 0.4165
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Entamoeba histolytica protein kinase domain containing protein 0.0615 0.2473 0.5664
Echinococcus granulosus lamin dm0 0.0028 0.0047 0.0078
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0455 0.1815 0.1813
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Schistosoma mansoni microtubule-associated protein tau 0.1421 0.5803 1
Brugia malayi tRNA modification GTPase TrmE family protein 0.0455 0.1815 0.4168
Entamoeba histolytica serine/threonine kinase, putative 0.0615 0.2473 0.5664
Onchocerca volvulus 0.0024 0.0031 0.005
Trichomonas vaginalis TKL family protein kinase 0.0615 0.2473 1
Schistosoma mansoni growth factor receptor-bound protein 0.0455 0.1815 0.3125
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.013 0.0472 0.1079
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0135 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0089 0.0348
Entamoeba histolytica tyrosine kinase, putative 0.0615 0.2473 0.5664
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Echinococcus granulosus geminin 0.0165 0.0614 0.1054
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.0623 0.0621
Entamoeba histolytica protein kinase, putative 0.0615 0.2473 0.5664
Onchocerca volvulus 0.0455 0.1815 0.4156
Brugia malayi SH2 domain containing protein 0.0455 0.1815 0.4168
Echinococcus granulosus GPCR family 2 0.0034 0.0073 0.0122
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0086 0.0216
Loa Loa (eye worm) TK protein kinase 0.0615 0.2473 0.5676
Echinococcus granulosus tyrosine kinase 0.107 0.4354 0.7503
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0142
Schistosoma mansoni tyrosine kinase 0.0615 0.2473 0.4259
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.107 0.4354 0.7503
Loa Loa (eye worm) hypothetical protein 0.0615 0.2473 0.5676
Loa Loa (eye worm) TK protein kinase 0.0615 0.2473 0.5676
Brugia malayi CXXC zinc finger family protein 0.0026 0.0041 0.0094
Brugia malayi Protein kinase domain containing protein 0.0615 0.2473 0.5679
Echinococcus multilocularis tensin 0.0455 0.1815 0.1813
Schistosoma mansoni amine GPCR 0.0024 0.0031 0.005
Echinococcus multilocularis tyrosine protein kinase Abl 0.107 0.4354 0.4353
Trichomonas vaginalis conserved hypothetical protein 0.0615 0.2473 1
Loa Loa (eye worm) TK/FER protein kinase 0.0615 0.2473 0.5676
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0106 0.0223
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0111 0.0244

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4.46 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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