Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0037 | 0.0122 | 0.0159 |
Echinococcus granulosus | glucose 6 phosphate 1 dehydrogenase | 0.0113 | 0.2872 | 0.2825 |
Echinococcus multilocularis | transcription factor eb | 0.013 | 0.3515 | 0.3472 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.0499 | 0.0553 |
Brugia malayi | histone deacetylase 11 | 0.0133 | 0.36 | 0.3647 |
Echinococcus granulosus | transcription factor eb | 0.013 | 0.3515 | 0.3472 |
Mycobacterium ulcerans | glucose-6-phosphate 1-dehydrogenase | 0.0113 | 0.2872 | 1 |
Plasmodium vivax | glucose-6-phosphate 1-dehydrogenase, putative | 0.0123 | 0.3235 | 0.3271 |
Schistosoma mansoni | endoplasmin | 0.0055 | 0.0795 | 0.0734 |
Trichomonas vaginalis | glucosamine-6-phosphate isomerase, putative | 0.0123 | 0.3235 | 0.3586 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0055 | 0.0795 | 0.0753 |
Brugia malayi | jmjC domain containing protein | 0.0115 | 0.297 | 0.2997 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.0499 | 0.0553 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0978 | 0.0941 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0037 | 0.0122 | 0.0057 |
Leishmania major | histone deacetylase, putative | 0.0282 | 0.9023 | 0.924 |
Echinococcus granulosus | histone deacetylase 1 | 0.0282 | 0.9023 | 0.9017 |
Loa Loa (eye worm) | endoplasmin | 0.0055 | 0.0795 | 0.0753 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0133 | 0.36 | 1 |
Mycobacterium ulcerans | glucose-6-phosphate 1-dehydrogenase | 0.0074 | 0.1456 | 0.3562 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0792 | 0.0731 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.4945 | 0.5035 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0309 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0205 | 0.6208 | 0.6183 |
Echinococcus multilocularis | heat shock protein 90 | 0.0055 | 0.0795 | 0.0734 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0055 | 0.0795 | 0.0699 |
Plasmodium falciparum | histone deacetylase, putative | 0.0302 | 0.9755 | 1 |
Trypanosoma cruzi | heat shock protein, putative | 0.0037 | 0.0122 | 0.002 |
Leishmania major | hypothetical protein, conserved | 0.0257 | 0.8103 | 0.8285 |
Brugia malayi | Histone deacetylase family protein | 0.0302 | 0.9755 | 1 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0282 | 0.9023 | 0.9245 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0043 | 0.0364 | 0.0301 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0282 | 0.9023 | 0.9017 |
Plasmodium vivax | heat shock protein 90, putative | 0.0037 | 0.0122 | 0.0058 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0052 | 0.0672 | 0.5 |
Schistosoma mansoni | heat shock protein | 0.0037 | 0.0122 | 0.0057 |
Toxoplasma gondii | histone deacetylase HDAC5 | 0.0133 | 0.36 | 0.3647 |
Giardia lamblia | Glucose-6-phosphate 1-dehydrogenase | 0.0123 | 0.3235 | 0.3538 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0037 | 0.0122 | 0.0058 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0047 | 0.0506 | 0.0417 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0055 | 0.0795 | 0.0753 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0792 | 0.0731 |
Leishmania major | glucose-6-phosphate 1-dehydrogenase, putative | 0.0113 | 0.2872 | 0.2855 |
Entamoeba histolytica | histone deacetylase, putative | 0.0282 | 0.9023 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0133 | 0.36 | 0.3623 |
Treponema pallidum | glucose-6-phosphate 1-dehydrogenase | 0.0113 | 0.2872 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0792 | 0.0731 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0282 | 0.9023 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0084 | 0.184 | 0.1786 |
Echinococcus multilocularis | heat shock protein 90 | 0.0047 | 0.0506 | 0.0443 |
Echinococcus granulosus | histone deacetylase 6 | 0.0302 | 0.9755 | 0.9753 |
Echinococcus multilocularis | glucose 6 phosphate 1 dehydrogenase | 0.0113 | 0.2872 | 0.2825 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0795 | 0.0699 |
Trichomonas vaginalis | chromobox protein, putative | 0.0051 | 0.0629 | 0.0697 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0282 | 0.9023 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0055 | 0.0795 | 0.0717 |
Echinococcus multilocularis | heat shock protein | 0.0055 | 0.0795 | 0.0734 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0795 | 0.0699 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0047 | 0.0499 | 0.1226 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0302 | 0.9755 | 0.9753 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0055 | 0.0795 | 0.0756 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0047 | 0.0506 | 0.0417 |
Echinococcus multilocularis | chromobox protein 1 | 0.0084 | 0.184 | 0.1786 |
Brugia malayi | jmjC domain containing protein | 0.0043 | 0.0334 | 0.0277 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.0795 | 0.0717 |
Giardia lamblia | Histone deacetylase | 0.0282 | 0.9023 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0792 | 0.0731 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0282 | 0.9023 | 0.9245 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0364 | 0.0272 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0795 | 0.0699 |
Leishmania major | histone deacetylase, putative | 0.0282 | 0.9023 | 0.924 |
Plasmodium vivax | heat shock protein 86, putative | 0.0055 | 0.0795 | 0.0753 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.0795 | 0.0717 |
Schistosoma mansoni | jumonji domain containing protein | 0.0092 | 0.2111 | 0.2058 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0073 | 0.1425 | 0.1403 |
Trypanosoma brucei | histone deacetylase 2 | 0.0133 | 0.36 | 0.361 |
Schistosoma mansoni | heat shock protein | 0.0055 | 0.0795 | 0.0734 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0282 | 0.9023 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0055 | 0.0795 | 0.0734 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Echinococcus granulosus | histone deacetylase 6 | 0.0302 | 0.9755 | 0.9753 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.013 | 0.0066 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0051 | 0.0629 | 0.1594 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0043 | 0.0364 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.3492 | 0.3536 |
Plasmodium vivax | histone deacetylase, putative | 0.0302 | 0.9755 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0084 | 0.184 | 0.1831 |
Echinococcus granulosus | endoplasmin | 0.0052 | 0.0672 | 0.061 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0282 | 0.9023 | 0.9242 |
Echinococcus granulosus | histone deacetylase 3 | 0.0282 | 0.9023 | 0.9017 |
Plasmodium falciparum | histone deacetylase 1 | 0.0282 | 0.9023 | 0.9245 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0282 | 0.9023 | 0.9242 |
Trichomonas vaginalis | glucosamine-6-phosphate isomerase, putative | 0.0123 | 0.3235 | 0.3586 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0282 | 0.9023 | 1 |
Trichomonas vaginalis | 6-phosphogluconolactonase, putative | 0.0123 | 0.3235 | 0.3586 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0302 | 0.9755 | 0.9753 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0144 | 0.4016 | 0.4077 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Echinococcus granulosus | histone deacetylase 8 | 0.0133 | 0.36 | 0.3557 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0795 | 0.0699 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0047 | 0.0506 | 0.0491 |
Toxoplasma gondii | glucose-6-phosphate 1-dehydrogenase | 0.0123 | 0.3235 | 0.3271 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0309 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.0795 | 0.0717 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0047 | 0.0506 | 0.0443 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0282 | 0.9023 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0282 | 0.9023 | 1 |
Schistosoma mansoni | chromobox protein | 0.0084 | 0.184 | 0.1786 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0115 | 0.297 | 0.2923 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0055 | 0.0795 | 0.0699 |
Brugia malayi | heat shock protein 90 | 0.0055 | 0.0795 | 0.0753 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0043 | 0.0364 | 0.0301 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0795 | 0.0699 |
Trichomonas vaginalis | chromobox protein, putative | 0.0051 | 0.0629 | 0.0697 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0115 | 0.297 | 0.2923 |
Plasmodium falciparum | heat shock protein 90, putative | 0.021 | 0.6392 | 0.6529 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0133 | 0.36 | 0.3557 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0792 | 0.0731 |
Trypanosoma brucei | glucose-6-phosphate 1-dehydrogenase | 0.0113 | 0.2872 | 0.2855 |
Trichomonas vaginalis | heat shock protein, putative | 0.0055 | 0.0795 | 0.0882 |
Echinococcus granulosus | jumonji domain containing protein | 0.0049 | 0.0566 | 0.0503 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0792 | 0.0731 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0052 | 0.0672 | 0.0571 |
Plasmodium vivax | histone deacetylase, putative | 0.0133 | 0.36 | 0.3647 |
Brugia malayi | chromobox protein homolog 3 | 0.0047 | 0.0499 | 0.0447 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0282 | 0.9023 | 0.9245 |
Giardia lamblia | Grp94/Hsp90 | 0.0052 | 0.0672 | 0.0677 |
Schistosoma mansoni | endoplasmin | 0.0055 | 0.0795 | 0.0734 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0055 | 0.0795 | 0.0815 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0302 | 0.9755 | 1 |
Brugia malayi | hypothetical protein | 0.0043 | 0.0364 | 0.0308 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0795 | 0.0699 |
Plasmodium vivax | heat shock protein, putative | 0.021 | 0.6392 | 0.6529 |
Echinococcus multilocularis | endoplasmin | 0.0052 | 0.0672 | 0.061 |
Trichomonas vaginalis | chromobox protein, putative | 0.0084 | 0.184 | 0.2039 |
Schistosoma mansoni | histone deacetylase | 0.0282 | 0.9023 | 0.9017 |
Brugia malayi | Heterochromatin protein 1 | 0.0084 | 0.184 | 0.1831 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0302 | 0.9755 | 1 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0052 | 0.0672 | 0.5 |
Trypanosoma cruzi | glucose-6-phosphate 1-dehydrogenase, putative | 0.0037 | 0.0142 | 0.0041 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0257 | 0.8103 | 0.8288 |
Trypanosoma cruzi | glucose-6-phosphate 1-dehydrogenase, putative | 0.0113 | 0.2872 | 0.2869 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0364 | 0.0272 |
Echinococcus multilocularis | histone deacetylase | 0.0302 | 0.9755 | 0.9753 |
Trichomonas vaginalis | heat shock protein, putative | 0.0047 | 0.0506 | 0.056 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0037 | 0.0122 | 0.0057 |
Leishmania major | histone deacetylase, putative | 0.0302 | 0.9755 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0055 | 0.0792 | 0.075 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0257 | 0.8103 | 0.8285 |
Plasmodium vivax | endoplasmin, putative | 0.0055 | 0.0795 | 0.0753 |
Plasmodium falciparum | glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | 0.0123 | 0.3235 | 0.3271 |
Trichomonas vaginalis | endoplasmin, putative | 0.004 | 0.0245 | 0.0272 |
Brugia malayi | MH2 domain containing protein | 0.0144 | 0.4016 | 0.4077 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.6208 | 0.6183 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0133 | 0.36 | 0.3557 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0792 | 0.0731 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0133 | 0.36 | 0.3623 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.0334 | 0.027 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Trichomonas vaginalis | heat shock protein, putative | 0.0052 | 0.0672 | 0.0745 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0037 | 0.0122 | 0.0058 |
Loa Loa (eye worm) | histone deacetylase | 0.0302 | 0.9755 | 1 |
Leishmania major | histone deacetylase, putative | 0.0302 | 0.9755 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0302 | 0.9755 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0302 | 0.9755 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Trichomonas vaginalis | chromobox protein, putative | 0.0084 | 0.184 | 0.2039 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0055 | 0.0792 | 0.075 |
Chlamydia trachomatis | glucose-6-phosphate 1-dehydrogenase | 0.0113 | 0.2872 | 0.5 |
Plasmodium falciparum | histone deacetylase 2 | 0.0302 | 0.9755 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0052 | 0.0672 | 0.0745 |
Loa Loa (eye worm) | helix-loop-helix DNA-binding domain-containing protein | 0.013 | 0.3492 | 0.3536 |
Loa Loa (eye worm) | glucose-6-phosphate dehydrogenase | 0.0113 | 0.2872 | 0.2896 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.519 | 0.5288 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0364 | 0.0272 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0795 | 0.0699 |
Echinococcus granulosus | heat shock protein 90 | 0.0047 | 0.0506 | 0.0443 |
Schistosoma mansoni | heat shock protein | 0.0055 | 0.0795 | 0.0734 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0282 | 0.9023 | 0.9017 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0043 | 0.0334 | 0.027 |
Brugia malayi | Hsp90 protein | 0.0037 | 0.0122 | 0.0058 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0049 | 0.0566 | 0.0503 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0499 | 0.0447 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0055 | 0.0795 | 0.0753 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0043 | 0.0334 | 0.0277 |
Trypanosoma brucei | histone deacetylase, putative | 0.0302 | 0.9755 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0144 | 0.4016 | 0.4077 |
Toxoplasma gondii | glucose-6-phosphate 1-dehydrogenase | 0.0074 | 0.1456 | 0.1435 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0055 | 0.0795 | 0.0717 |
Brugia malayi | Histone deacetylase 1 | 0.0282 | 0.9023 | 0.9245 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0055 | 0.0795 | 0.0699 |
Brugia malayi | Helix-loop-helix DNA-binding domain containing protein | 0.013 | 0.3515 | 0.356 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0043 | 0.0334 | 0.027 |
Trypanosoma brucei | histone deacetylase 4 | 0.0302 | 0.9755 | 1 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0282 | 0.9023 | 0.9245 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0052 | 0.0672 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0364 | 0.0272 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0257 | 0.8103 | 0.8288 |
Plasmodium falciparum | heat shock protein 90 | 0.0055 | 0.0795 | 0.0753 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0795 | 0.0699 |
Echinococcus granulosus | geminin | 0.0205 | 0.6208 | 0.6183 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.9023 | 0.9245 |
Plasmodium falciparum | endoplasmin, putative | 0.004 | 0.0245 | 0.0185 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0133 | 0.36 | 0.3557 |
Echinococcus granulosus | heat shock protein | 0.0055 | 0.0795 | 0.0734 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.6208 | 0.6183 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0302 | 0.9755 | 0.9753 |
Brugia malayi | glucose-6-phosphate dehydrogenase | 0.0113 | 0.2872 | 0.2896 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0302 | 0.9755 | 1 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0133 | 0.36 | 0.3647 |
Brugia malayi | Endoplasmin precursor | 0.0055 | 0.0795 | 0.0753 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0282 | 0.9023 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.004 | 0.0245 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.36 | 0.3647 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0282 | 0.9023 | 0.9245 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0282 | 0.9023 | 1 |
Trypanosoma brucei | histone deacetylase 3 | 0.0302 | 0.9755 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0302 | 0.9755 | 0.9753 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.0133 | 0.36 | 0.3647 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0302 | 0.9755 | 0.9753 |
Echinococcus granulosus | histone deacetylase 7 | 0.0302 | 0.9755 | 0.9753 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0302 | 0.9755 | 1 |
Schistosoma mansoni | glucose-6-phosphate 1-dehydrogenase | 0.0113 | 0.2872 | 0.2825 |
Schistosoma mansoni | chromobox protein | 0.0084 | 0.184 | 0.1786 |
Echinococcus granulosus | chromobox protein 1 | 0.0084 | 0.184 | 0.1786 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0364 | 0.0301 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.021 | 0.6392 | 0.6529 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0795 | 0.0699 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0302 | 0.9755 | 1 |
Onchocerca volvulus | 0.0037 | 0.013 | 0.0181 | |
Entamoeba histolytica | heat shock protein 90, putative | 0.0055 | 0.0795 | 0.0756 |
Trypanosoma brucei | histone deacetylase 1 | 0.0282 | 0.9023 | 0.924 |
Schistosoma mansoni | histone deacetylase | 0.0282 | 0.9023 | 0.9017 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0282 | 0.9023 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.0334 | 0.027 |
Echinococcus granulosus | chromobox protein 1 | 0.0084 | 0.184 | 0.1786 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0282 | 0.9023 | 0.9245 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0282 | 0.9023 | 0.9245 |
Echinococcus granulosus | histone deacetylase | 0.0302 | 0.9755 | 0.9753 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.659 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.538 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.45 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.366 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.359 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.287 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.281 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.921 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.646 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.418 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.