Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0467 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0028 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0511 | 0.097 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0017 | 0.0241 | 0.0356 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0126 | 0.0126 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0012 | 0.0126 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0241 | 0.041 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0017 | 0.0241 | 0.0416 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0133 | 0.3326 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0133 | 0.3326 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0044 | 0.0044 |
Schistosoma mansoni | peptidase | 0.0017 | 0.0241 | 0.0241 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0133 | 0.3326 | 0.6819 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0133 | 0.3326 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0133 | 0.3326 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0012 | 0.0126 | 0.0126 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.003 | 0.058 | 0.1099 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0018 | 0.0277 | 1 |
Schistosoma mansoni | Xaa-Pro dipeptidase (M24 family) | 0.0017 | 0.0241 | 0.0241 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0012 | 0.0126 | 0.0126 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0133 | 0.3326 | 1 |
Echinococcus multilocularis | methionine aminopeptidase, type I | 0.0017 | 0.0241 | 0.0241 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.1129 | 0.2259 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0051 | 0.1142 | 0.3171 |
Loa Loa (eye worm) | initiation factor 2-associated protein | 0.0017 | 0.0241 | 0.041 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0126 | 0.0126 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0664 | 0.1294 |
Onchocerca volvulus | 0.0028 | 0.0535 | 0.0553 | |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0191 | 0.4858 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0052 | 0.1179 | 0.3042 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0012 | 0.0126 | 0.0126 |
Echinococcus granulosus | FACT complex subunit SPT16 | 0.0017 | 0.0241 | 0.0241 |
Trypanosoma brucei | Xaa-Pro aminopeptidase, putative | 0.0017 | 0.0241 | 0.0356 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0133 | 0.3326 | 1 |
Echinococcus granulosus | xaa pro aminopeptidase | 0.0017 | 0.0241 | 0.0241 |
Brugia malayi | initiation factor 2-associated protein. | 0.0017 | 0.0241 | 0.0416 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1129 | 0.1129 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0511 | 0.0511 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0467 |
Trichomonas vaginalis | set domain proteins, putative | 0.0217 | 0.5555 | 1 |
Echinococcus granulosus | Xaa Pro aminopeptidase 3 | 0.0017 | 0.0241 | 0.0241 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0018 | 0.0277 | 0.049 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0039 | 0.0842 | 0.1663 |
Trypanosoma brucei | Metallopeptidase family M24, putative | 0.0017 | 0.0241 | 0.0356 |
Loa Loa (eye worm) | DNA-binding protein | 0.0017 | 0.0241 | 0.041 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0017 | 0.0241 | 0.0356 |
Echinococcus granulosus | dna polymerase eta | 0.0042 | 0.0912 | 0.0912 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0018 | 0.0277 | 0.0067 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0133 | 0.3326 | 1 |
Schistosoma mansoni | proliferation-associated protein 2G4 38kDa (M24 family) | 0.0017 | 0.0241 | 0.0241 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0133 | 0.3326 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0051 | 0.1142 | 0.2919 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0044 | 0.0044 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0115 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0133 | 0.3326 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0191 | 0.4858 | 1 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0133 | 0.3326 | 0.3326 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0553 | 0.0553 |
Brugia malayi | Pre-SET motif family protein | 0.0028 | 0.0535 | 0.1026 |
Leishmania major | DNA polymerase eta, putative | 0.0042 | 0.0912 | 0.2176 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0028 | 0.0535 | 0.0535 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1129 | 0.1129 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0467 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0115 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0467 |
Echinococcus multilocularis | xaa pro aminopeptidase | 0.0017 | 0.0241 | 0.0241 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0115 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0133 | 0.3326 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0018 | 0.0277 | 0.0467 |
Echinococcus multilocularis | xaa Pro dipeptidase | 0.0017 | 0.0241 | 0.0241 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0018 | 0.0277 | 0.0277 |
Schistosoma mansoni | aminopeptidase P1 (M24 family) | 0.0017 | 0.0241 | 0.0241 |
Echinococcus multilocularis | GPCR, family 2 | 0.0012 | 0.0126 | 0.0126 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0018 | 0.0277 | 0.0277 |
Echinococcus granulosus | dna polymerase kappa | 0.0018 | 0.0277 | 0.0277 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0018 | 0.0277 | 0.0115 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0039 | 0.0842 | 0.1663 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0042 | 0.0912 | 0.2454 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0042 | 0.0912 | 0.2176 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0028 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0039 | 0.0842 | 0.1658 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0012 | 0.0126 | 0.0178 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0133 | 0.3326 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0241 | 0.041 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0026 | 0.0493 | 0.0493 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0018 | 0.0277 | 0.0467 |
Echinococcus granulosus | xaa Pro dipeptidase | 0.0017 | 0.0241 | 0.0241 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0133 | 0.3326 | 0.6817 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0018 | 0.0277 | 0.0115 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0018 | 0.0277 | 0.0115 |
Echinococcus granulosus | GPCR family 2 | 0.0012 | 0.0126 | 0.0126 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.1142 | 0.2919 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0018 | 0.0277 | 0.0484 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0467 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0467 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0018 | 0.0277 | 0.0067 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0385 | 1 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0018 | 0.0277 | 0.0277 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0133 | 0.3326 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0133 | 0.3326 | 1 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0133 | 0.3326 | 1 |
Echinococcus granulosus | Proliferation associated protein 2G4 | 0.0017 | 0.0241 | 0.0241 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0133 | 0.3326 | 1 |
Schistosoma mansoni | proliferation-associated protein 2G4 38kDa (M24 family) | 0.0017 | 0.0241 | 0.0241 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0467 |
Trypanosoma brucei | unspecified product | 0.0018 | 0.0277 | 0.0467 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0467 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0133 | 0.3326 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0126 | 0.0172 |
Echinococcus multilocularis | xaa Pro dipeptidase | 0.0017 | 0.0241 | 0.0241 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0241 | 0.041 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0912 | 0.1804 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.1142 | 0.2919 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0018 | 0.0277 | 0.0277 |
Toxoplasma gondii | methionine aminopeptidase | 0.0133 | 0.3326 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0027 | 0.0511 | 0.0976 |
Echinococcus granulosus | methionine aminopeptidase type I | 0.0017 | 0.0241 | 0.0241 |
Brugia malayi | DNA-binding protein, 42 kDa containing protein | 0.0017 | 0.0241 | 0.0416 |
Toxoplasma gondii | methionine aminopeptidase | 0.0133 | 0.3326 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0553 | 0.0553 |
Plasmodium vivax | SET domain protein, putative | 0.0028 | 0.0535 | 0.0952 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1129 | 0.1129 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.4847 | 0.4847 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0133 | 0.3326 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1129 | 0.1129 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0017 | 0.0241 | 0.0416 |
Echinococcus multilocularis | Proliferation associated protein 2G4 | 0.0017 | 0.0241 | 0.0241 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.1142 | 0.2919 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0028 | 0.0535 | 0.0952 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0018 | 0.0277 | 0.0467 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0028 | 0.0535 | 0.0535 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0467 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0133 | 0.3326 | 0.3326 |
Schistosoma mansoni | methionyl aminopeptidase 2 (M24 family) | 0.0017 | 0.0241 | 0.0241 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0467 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0133 | 0.3326 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0842 | 0.1658 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1129 | 0.1129 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0133 | 0.3326 | 0.3326 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.4847 | 0.4847 |
Leishmania major | DNA polymerase eta, putative | 0.003 | 0.058 | 0.1099 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0012 | 0.0126 | 0.0126 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0017 | 0.0241 | 0.0416 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0133 | 0.3326 | 0.3326 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0133 | 0.3326 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1129 | 0.1129 |
Schistosoma mansoni | chromatin-specific transcription elongation factor 140 kDa subunit (M24 family) | 0.0017 | 0.0241 | 0.0241 |
Leishmania major | hypothetical protein, conserved | 0.0051 | 0.1142 | 0.2919 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0018 | 0.0277 | 0.0115 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0133 | 0.3326 | 0.3326 |
Trypanosoma brucei | Facilitates chromatin transcription complex subunit spt16 | 0.0017 | 0.0241 | 0.0356 |
Echinococcus granulosus | methionyl aminopeptidase 2 | 0.0017 | 0.0241 | 0.0241 |
Leishmania major | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0115 |
Echinococcus granulosus | geminin | 0.019 | 0.4847 | 0.4847 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0027 | 0.0512 | 0.0973 |
Brugia malayi | hypothetical protein | 0.0051 | 0.1142 | 0.2285 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0012 | 0.0126 | 0.0172 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0126 | 0.0126 |
Echinococcus multilocularis | methionyl aminopeptidase 2 | 0.0017 | 0.0241 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1142 | 0.228 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0042 | 0.0912 | 0.1809 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.003 | 0.058 | 0.1099 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0535 | 0.102 |
Brugia malayi | CXXC zinc finger family protein | 0.0027 | 0.0512 | 0.0978 |
Echinococcus multilocularis | dna polymerase eta | 0.0042 | 0.0912 | 0.0912 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.1142 | 0.2919 |
Onchocerca volvulus | 0.0027 | 0.0512 | 0.0509 | |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0028 | 0.0535 | 0.0535 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0051 | 0.1142 | 0.2919 |
Onchocerca volvulus | 0.0217 | 0.5555 | 1 | |
Echinococcus multilocularis | geminin | 0.019 | 0.4847 | 0.4847 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0553 | 0.0553 |
Echinococcus multilocularis | Xaa Pro aminopeptidase 3 | 0.0017 | 0.0241 | 0.0241 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0018 | 0.0277 | 0.0115 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0058 | 0.1342 | 0.1342 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0133 | 0.3326 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0027 | 0.0512 | 0.0512 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0028 | 0.0535 | 0.0535 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | metallopeptidase family M24 containing protein | 0.0017 | 0.0241 | 0.041 |
Echinococcus granulosus | xaa Pro dipeptidase | 0.0017 | 0.0241 | 0.0241 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.1129 | 0.2254 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1129 | 0.1129 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0399 | 0.0399 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0018 | 0.0277 | 0.0115 |
Trypanosoma brucei | methionine aminopeptidase 2, putative | 0.0017 | 0.0241 | 0.0356 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0399 | 0.0399 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0553 | 0.0553 |
Echinococcus multilocularis | FACT complex subunit SPT16 | 0.0017 | 0.0241 | 0.0241 |
Echinococcus multilocularis | dna polymerase kappa | 0.0018 | 0.0277 | 0.0277 |
Giardia lamblia | DINP protein human, muc B family | 0.0018 | 0.0277 | 1 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0017 | 0.0241 | 0.0356 |
Schistosoma mansoni | aminopeptidase P homologue (M24 family) | 0.0017 | 0.0241 | 0.0241 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0028 | 0.0535 | 0.0535 |
Schistosoma mansoni | DNA polymerase eta | 0.0042 | 0.0912 | 0.0912 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.