TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 392.555 | Formula: C21H32N2O3S
H donors: 1 H acceptors: 3 LogP: 3.92 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: O=C(C1CCN(CC1)S(=O)(=O)c1cc(C)cc(c1)C)NC1CCCCCC1
InChi: 1S/C21H32N2O3S/c1-16-13-17(2)15-20(14-16)27(25,26)23-11-9-18(10-12-23)21(24)22-19-7-5-3-4-6-8-19/h13-15,18-19H,3-12H2,1-2H3,(H,22,24)
InChiKey: QNSCBADBMXEFML-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	epoxide hydrolase 2, cytoplasmic	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Mycobacterium tuberculosis	Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase)	Get druggable targets OG5_129061	All targets in OG5_129061
Mycobacterium ulcerans	epoxide hydrolase EphA	Get druggable targets OG5_129061	All targets in OG5_129061

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0085	0.0588	0.0843
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0247	0.0332
Loa Loa (eye worm)	TAR-binding protein	0.0062	0.0392	0.055
Echinococcus multilocularis	nuclear receptor nhr 48	0.004	0.0206	0.0188
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0045	0.0245	0.0221
Trypanosoma brucei	DNA polymerase eta, putative	0.0044	0.0237	0.0318
Loa Loa (eye worm)	steroid hormone receptor	0.0085	0.0588	0.0843
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0085	0.0588	0.0843
Brugia malayi	hypothetical protein	0.0045	0.0247	0.0368
Brugia malayi	Nuclear hormone receptor E75	0.004	0.0206	0.0307
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.004	0.0206	0.0181
Schistosoma mansoni	flap endonuclease-1	0.0023	0.0061	0.0035
Giardia lamblia	Flap structure-specific endonuclease	0.0025	0.0081	1
Echinococcus multilocularis	flap endonuclease 1	0.0025	0.0081	0.0059
Schistosoma mansoni	tar DNA-binding protein	0.0062	0.0392	0.0368
Trypanosoma brucei	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.08	0.6702	1
Plasmodium vivax	flap endonuclease 1, putative	0.0025	0.0081	1
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.004	0.0206	0.0188
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0085	0.0588	0.0587
Brugia malayi	nuclear receptor RXR	0.004	0.0206	0.0307
Schistosoma mansoni	nuclear hormone receptor	0.0085	0.0588	0.0564
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0247	0.0332
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0085	0.0588	0.0587
Brugia malayi	tailless protein	0.004	0.0206	0.0307
Echinococcus granulosus	flap endonuclease 1	0.0025	0.0081	0.0056
Brugia malayi	Steroid receptor seven-up type 2	0.0085	0.0588	0.0878
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0085	0.0588	0.0843
Echinococcus multilocularis	FTZ F1 alpha	0.0085	0.0588	0.0587
Echinococcus granulosus	tyrosyl DNA phosphodiesterase 1	0.08	0.6702	0.6693
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0237	0.0318
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0085	0.0588	0.0564
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0588	0.0843
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0045	0.0247	0.0222
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0085	0.0588	0.0878
Loa Loa (eye worm)	RNA binding protein	0.0062	0.0392	0.055
Schistosoma mansoni	hypothetical protein	0.0165	0.1276	0.1254
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0085	0.0588	0.0587
Brugia malayi	nuclear receptor NHR-88	0.004	0.0206	0.0307
Echinococcus granulosus	FTZ F1 alpha	0.0085	0.0588	0.0564
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.004	0.0206	0.027
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0085	0.0588	0.0878
Brugia malayi	nuclear receptor NHR-67	0.004	0.0206	0.0307
Entamoeba histolytica	hypothetical protein	0.0035	0.0164	0.0208
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0085	0.0588	0.0564
Schistosoma mansoni	nuclear hormone receptor	0.004	0.0206	0.0181
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0045	0.0245	0.023
Mycobacterium tuberculosis	Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase)	0.0197	0.1552	1
Schistosoma mansoni	transcription factor LCR-F1	0.0035	0.0164	0.0139
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.004	0.0206	0.0188
Schistosoma mansoni	tyrosyl-DNA phosphodiesterase	0.08	0.6702	0.6693
Schistosoma mansoni	thyroid hormone receptor	0.0085	0.0588	0.0564
Brugia malayi	nuclear hormone receptor	0.004	0.0206	0.0307
Schistosoma mansoni	tar DNA-binding protein	0.0062	0.0392	0.0368
Brugia malayi	ImpB/MucB/SamB family protein	0.0044	0.0237	0.0354
Echinococcus granulosus	ecdysone induced protein 78C	0.0085	0.0588	0.0564
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0085	0.0588	0.0587
Loa Loa (eye worm)	nuclear hormone receptor	0.004	0.0206	0.027
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0588	0.0843
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0588	0.0843
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0085	0.0588	0.0878
Schistosoma mansoni	nuclear receptor nhr-48	0.004	0.0206	0.0181
Leishmania major	flap endonuclease-1 (FEN-1), putative	0.0025	0.0081	0.0084
Schistosoma mansoni	nuclear hormone receptor	0.004	0.0206	0.0181
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0085	0.0588	0.0878
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0085	0.0588	0.0878
Entamoeba histolytica	tyrosyl-DNA phosphodiesterase, putative	0.08	0.6702	1
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.004	0.0206	0.0181
Entamoeba histolytica	hypothetical protein	0.0035	0.0164	0.0208
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Loa Loa (eye worm)	tyrosyl-DNA phosphodiesterase	0.08	0.6702	1
Brugia malayi	hypothetical protein	0.004	0.0206	0.0307
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0035	0.0164	0.0145
Echinococcus granulosus	thyroid hormone receptor alpha	0.004	0.0206	0.0181
Brugia malayi	photoreceptor-specific nuclear receptor	0.0085	0.0588	0.0878
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0085	0.0588	0.0564
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0045	0.0245	0.0221
Schistosoma mansoni	thyroid hormone receptor	0.0085	0.0588	0.0564
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0085	0.0588	0.0564
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0085	0.0588	0.0878
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.004	0.0206	0.0188
Schistosoma mansoni	coup transcription factor	0.0085	0.0588	0.0564
Brugia malayi	Nuclear hormone receptor-like 1	0.0045	0.0247	0.0368
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Toxoplasma gondii	ImpB/MucB/SamB family protein	0.0031	0.0127	1
Brugia malayi	ImpB/MucB/SamB family protein	0.0019	0.0025	0.0038
Echinococcus granulosus	transcription factor Dp 1	0.0463	0.3822	0.3806
Echinococcus granulosus	dna polymerase eta	0.0044	0.0237	0.0213
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0045	0.0245	0.0366
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0085	0.0588	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0085	0.0588	0.0843
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0085	0.0588	0.0843
Echinococcus multilocularis	ecdysone induced protein 78C	0.0085	0.0588	0.0587
Brugia malayi	Nuclear hormone receptor-like 1	0.0085	0.0588	0.0878
Loa Loa (eye worm)	nuclear receptor NHR-67	0.004	0.0206	0.027
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0085	0.0588	0.0564
Brugia malayi	nuclear receptor RXR	0.0045	0.0247	0.0368
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0247	0.0332
Schistosoma mansoni	tar DNA-binding protein	0.0062	0.0392	0.0368
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.004	0.0206	0.0181
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0588	0.0843
Echinococcus multilocularis	tar DNA binding protein	0.0062	0.0392	0.0383
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0085	0.0588	0.0878
Brugia malayi	RNA binding protein	0.0062	0.0392	0.0585
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0085	0.0588	0.0564
Brugia malayi	hypothetical protein	0.004	0.0206	0.0307
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0085	0.0588	0.0878
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0085	0.0588	0.0564
Mycobacterium ulcerans	epoxide hydrolase EphA	0.0197	0.1552	1
Echinococcus multilocularis	tyrosyl DNA phosphodiesterase 1	0.08	0.6702	0.696
Trypanosoma cruzi	DNA polymerase eta, putative	0.0044	0.0237	0.0318
Schistosoma mansoni	hypothetical protein	0.0035	0.0164	0.0139
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0085	0.0588	0.0878
Brugia malayi	ecdysteroid receptor	0.0085	0.0588	0.0878
Brugia malayi	nuclear hormone receptor family member nhr-6	0.004	0.0206	0.0307
Trypanosoma brucei	PAB1-binding protein , putative	0.0025	0.0074	0.0074
Leishmania major	DNA polymerase eta, putative	0.0031	0.0127	0.0152
Schistosoma mansoni	DNA polymerase eta	0.0044	0.0237	0.0213
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0085	0.0588	0.0564
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0045	0.0247	0.0332
Echinococcus granulosus	geminin	0.0165	0.1276	0.1254
Schistosoma mansoni	tar DNA-binding protein	0.0062	0.0392	0.0368
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0247	0.0332
Schistosoma mansoni	retinoic acid receptor RXR	0.1186	1	1
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Leishmania major	DNA polymerase eta, putative	0.0044	0.0237	0.0318
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0588	0.0843
Leishmania major	tyrosyl-DNA phosphodiesterase 1	0.08	0.6702	1
Brugia malayi	Nuclear hormone receptor-like 1	0.0045	0.0247	0.0368
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0074	0.0074
Schistosoma mansoni	tar DNA-binding protein	0.0062	0.0392	0.0368
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0045	0.0245	0.0221
Entamoeba histolytica	hypothetical protein	0.0035	0.0164	0.0208
Brugia malayi	TAR-binding protein	0.0062	0.0392	0.0585
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.1141	0.9618	1
Brugia malayi	nuclear hormone receptor	0.0085	0.0588	0.0878
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Onchocerca volvulus		0.0085	0.0588	1
Brugia malayi	Nuclear hormone receptor E75	0.004	0.0206	0.0307
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0085	0.0588	0.0564
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0085	0.0588	0.0878
Toxoplasma gondii	flap structure-specific endonuclease 1, putative	0.0025	0.0081	0.1335
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0247	0.0332
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0074	0.0074
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Brugia malayi	orphan nuclear receptor NR2E1	0.004	0.0206	0.0307
Brugia malayi	RNA recognition motif domain containing protein	0.0062	0.0392	0.0585
Schistosoma mansoni	nuclear receptor	0.004	0.0206	0.0181
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0085	0.0588	0.0564
Brugia malayi	ecdysone receptor	0.004	0.0206	0.0307
Loa Loa (eye worm)	flap endonuclease-1	0.0025	0.0081	0.0084
Leishmania major	hypothetical protein, conserved	0.0025	0.0074	0.0074
Entamoeba histolytica	Flap nuclease, putative	0.0025	0.0081	0.0084
Brugia malayi	hypothetical protein	0.0025	0.0074	0.0111
Brugia malayi	hypothetical protein	0.0035	0.0164	0.0245
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0588	0.0843
Trypanosoma brucei	flap endonuclease-1 (FEN-1), putative	0.0025	0.0081	0.0084
Brugia malayi	hypothetical protein	0.0045	0.0247	0.0368
Brugia malayi	Tyrosyl-DNA phosphodiesterase family protein	0.08	0.6702	1
Trypanosoma cruzi	flap endonuclease-1 (FEN-1), putative	0.0025	0.0081	0.0084
Schistosoma mansoni	RAR-like nuclear receptor	0.0085	0.0588	0.0564
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0085	0.0588	0.0843
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0085	0.0588	0.0587
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0045	0.0245	0.023
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0062	0.0392	0.055
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0588	0.0843
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.004	0.0206	0.0181
Entamoeba histolytica	hypothetical protein	0.0035	0.0164	0.0208
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0045	0.0245	0.0221
Onchocerca volvulus	Bile acid receptor homolog	0.0085	0.0588	1
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0085	0.0588	0.0878
Brugia malayi	Flap endonuclease-1	0.0025	0.0081	0.0121
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.08	0.6702	1
Schistosoma mansoni	hypothetical protein	0.0165	0.1276	0.1254
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0085	0.0588	0.0878
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0035	0.0164	0.0139
Plasmodium falciparum	flap endonuclease 1	0.0025	0.0081	1
Echinococcus multilocularis	dna polymerase eta	0.0044	0.0237	0.0221
Loa Loa (eye worm)	hypothetical protein	0.004	0.0206	0.027
Echinococcus granulosus	Nuclear hormone receptor HR96	0.004	0.0206	0.0181
Echinococcus multilocularis	geminin	0.0165	0.1276	0.1304
Schistosoma mansoni	nuclear receptor	0.004	0.0206	0.0181
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0588	0.0843
Brugia malayi	nuclear receptor NHR-88	0.0085	0.0588	0.0878
Trypanosoma cruzi	DNA polymerase eta, putative	0.0031	0.0127	0.0152
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0045	0.0247	0.0231
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0085	0.0588	0.0587
Onchocerca volvulus	Protein ultraspiracle homolog	0.0085	0.0588	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0045	0.0245	0.0221
Echinococcus granulosus	nuclear receptor nhr 48	0.004	0.0206	0.0181
Schistosoma mansoni	zinc finger protein	0.004	0.0206	0.0181
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0085	0.0588	0.0587
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.004	0.0206	0.0307
Loa Loa (eye worm)	DR-78	0.004	0.0206	0.027
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0085	0.0588	0.0878
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0085	0.0588	0.0564
Echinococcus granulosus	Nuclear hormone receptor HR96	0.004	0.0206	0.0181
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0085	0.0588	0.0564
Brugia malayi	conserved hypotetical protein	0.004	0.0206	0.0307
Echinococcus granulosus	tar DNA binding protein	0.0062	0.0392	0.0368
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0074	0.0074
Brugia malayi	nuclear hormone receptor family member odr-7	0.004	0.0206	0.0307
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.08	0.6702	1
Trichomonas vaginalis	flap endonuclease-1, putative	0.0025	0.0081	1
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.004	0.0206	0.0188
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0045	0.0247	0.0222
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0085	0.0588	0.0564
Brugia malayi	steroid hormone receptor	0.0085	0.0588	0.0878
Echinococcus multilocularis	transcription factor Dp 1	0.0463	0.3822	0.3958
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0045	0.0245	0.033
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0045	0.0247	0.0222
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0085	0.0588	0.0843

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 2000 nM	Inhibition of human soluble epoxide hydrolase using CMNPC as substrate after 5 mins by fluorescent assay	ChEMBL.	22079754

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1933658

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1595328