Detailed information for compound 1597607

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 437.356 | Formula: C22H15NO9
  • H donors: 6 H acceptors: 7 LogP: 2.89 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 2
  • SMILES: Oc1cc(O)c2c(c1)oc(c(c2=O)OC(=O)c1ccc(c(c1)N)O)c1ccc(c(c1)O)O
  • InChi: 1S/C22H15NO9/c23-12-5-10(2-3-13(12)25)22(30)32-21-19(29)18-16(28)7-11(24)8-17(18)31-20(21)9-1-4-14(26)15(27)6-9/h1-8,24-28H,23H2
  • InChiKey: HKABVAZPZRSPQV-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma brucei unspecified product 0.0022 0.1476 0.1136
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.2281 0.1414
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.1476 0.1476
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.1386 0.1132
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.101 0.0994
Schistosoma mansoni lipoxygenase 0.0022 0.1552 0.1552
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.1552 0.1538
Schistosoma mansoni hypothetical protein 0.0013 0.0018 0.0018
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.1552 0.1552
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.2281 0.5
Loa Loa (eye worm) hypothetical protein 0.0022 0.1552 0.1552
Echinococcus granulosus dna polymerase kappa 0.0022 0.1476 0.1476
Brugia malayi AMP-binding enzyme family protein 0.0027 0.2281 0.2281
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.1476 0.0519
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Brugia malayi Cathepsin L-like precursor 0.0019 0.101 0.101
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.101 0.101
Echinococcus multilocularis transcription factor btf3 0.0039 0.4334 0.4324
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.2281 0.5
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.1386 0.5
Brugia malayi TAR-binding protein 0.0071 0.9514 0.9514
Brugia malayi hypothetical protein 0.0022 0.1552 0.1552
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.1476 0.0519
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.101 0.101
Echinococcus multilocularis RUN 0.0022 0.1552 0.1538
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.452 0.452
Schistosoma mansoni tar DNA-binding protein 0.0071 0.9514 0.9514
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.1187 0.0533
Echinococcus granulosus cathepsin l1 0.0019 0.101 0.101
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.101 0.233
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.1476 0.1476
Entamoeba histolytica hypothetical protein 0.0041 0.452 0.452
Onchocerca volvulus 0.0019 0.101 0.4428
Trypanosoma cruzi cruzipain precursor, putative 0.0072 0.9595 0.955
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.1476 0.1136
Brugia malayi hypothetical protein 0.0022 0.1552 0.1552
Onchocerca volvulus 0.0019 0.101 0.4428
Brugia malayi hypothetical protein 0.0018 0.0924 0.0924
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.1476 0.1476
Entamoeba histolytica hypothetical protein 0.0039 0.4334 0.4334
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.1187 0.139
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.1386 0.1043
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.4334 0.4334
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.2281 0.1414
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.1476 0.1476
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.2554 0.4645
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.2281 1
Leishmania major cathepsin L-like protease 0.0072 0.9595 0.955
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.1476 0.2642
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.101 0.101
Brugia malayi AMP-binding enzyme family protein 0.0027 0.2281 0.2281
Schistosoma mansoni tar DNA-binding protein 0.0071 0.9514 0.9514
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.1476 0.1136
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.1476 0.1136
Toxoplasma gondii NAC domain-containing protein 0.0039 0.4334 1
Echinococcus multilocularis tar DNA binding protein 0.0071 0.9514 0.9513
Entamoeba histolytica hypothetical protein 0.0041 0.452 0.452
Echinococcus granulosus RUN 0.0022 0.1552 0.1552
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.1476 0.1136
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.101 0.233
Echinococcus granulosus transcription factor Dp 1 0.0043 0.4927 0.4927
Giardia lamblia DINP protein human, muc B family 0.0022 0.1476 1
Schistosoma mansoni lipoxygenase 0.0062 0.8028 0.8028
Brugia malayi AMP-binding enzyme family protein 0.0027 0.2281 0.2281
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 1 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.2281 0.2281
Onchocerca volvulus Cathepsin L homolog 0.0019 0.101 0.4428
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.4334 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Schistosoma mansoni rab6-interacting 0.0022 0.1552 0.1552
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.101 0.233
Leishmania major cathepsin L-like protease 0.0072 0.9595 0.955
Brugia malayi RNA recognition motif domain containing protein 0.0071 0.9514 0.9514
Brugia malayi Cathepsin L-like precursor 0.0019 0.101 0.101
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.2281 1
Brugia malayi Cathepsin L-like precursor 0.0019 0.101 0.101
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0062 0.8028 0.8025
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 1 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.2281 0.2281
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.2281 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.452 0.451
Loa Loa (eye worm) TAR-binding protein 0.0071 0.9514 0.9514
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.4334 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Echinococcus granulosus dna polymerase eta 0.0022 0.1476 0.1476
Schistosoma mansoni hypothetical protein 0.0041 0.452 0.452
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.101 0.233
Loa Loa (eye worm) ctsf protein 0.0019 0.101 0.101
Schistosoma mansoni tar DNA-binding protein 0.0071 0.9514 0.9514
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 1 1
Loa Loa (eye worm) hypothetical protein 0.002 0.1187 0.1187
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 1 1
Schistosoma mansoni ap endonuclease 0.0021 0.1386 0.1386
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.101 0.101
Schistosoma mansoni rab6-interacting 0.0022 0.1552 0.1552
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.101 0.101
Echinococcus multilocularis dna polymerase kappa 0.0022 0.1476 0.1461
Onchocerca volvulus 0.0019 0.101 0.4428
Brugia malayi Cathepsin L-like precursor 0.0019 0.101 0.101
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.1386 0.1386
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Loa Loa (eye worm) cysteine protease 0.0019 0.101 0.101
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.2281 0.2281
Loa Loa (eye worm) fibroinase 0.0019 0.101 0.101
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.1476 0.1136
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.101 0.233
Brugia malayi Cathepsin L-like precursor 0.0019 0.101 0.101
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.2554 0.4645
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.101 0.101
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 1 1
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.1476 0.1136
Schistosoma mansoni ap endonuclease 0.0021 0.1386 0.1386
Loa Loa (eye worm) hypothetical protein 0.0019 0.101 0.101
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.101 0.0994
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.1386 0.1822
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.2554 0.4645
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.2554 0.2257
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.1476 0.1136
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.1476 0.0519
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.1386 0.1386
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.1476 0.1136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Brugia malayi Cathepsin L-like precursor 0.0019 0.101 0.101
Schistosoma mansoni tar DNA-binding protein 0.0071 0.9514 0.9514
Plasmodium falciparum acyl-CoA synthetase 0.002 0.1187 0.0533
Onchocerca volvulus 0.0019 0.101 0.4428
Onchocerca volvulus Cathepsin F homolog 0.0019 0.101 0.4428
Onchocerca volvulus Cathepsin L homolog 0.0019 0.101 0.4428
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.1552 0.1538
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.101 0.233
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.4334 0.4109
Brugia malayi hypothetical protein 0.0041 0.452 0.452
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.2281 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.1386 0.0419
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.1476 0.3406
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.1552 0.1632
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.1386 0.1386
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.1476 0.1136
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.1476 0.2642
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.4334 1
Leishmania major cathepsin L-like protease 0.0072 0.9595 0.955
Echinococcus granulosus transcription factor btf3 0.0039 0.4334 0.4334
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.1476 0.3406
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.101 0.0994
Leishmania major hypothetical protein, conserved 0.0028 0.2554 0.1718
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.1476 0.3665
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.1476 0.1476
Loa Loa (eye worm) hypothetical protein 0.0028 0.2554 0.2554
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.1476 0.1136
Loa Loa (eye worm) hypothetical protein 0.0027 0.2281 0.2281
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.2281 1
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.4334 0.3698
Leishmania major DNA polymerase kappa, putative 0.0022 0.1476 0.0519
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.101 0.233
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.1476 0.1476
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.7104 0.6779
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.1476 0.0519
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.2281 1
Loa Loa (eye worm) RNA binding protein 0.0071 0.9514 0.9514
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.4334 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.1552 0.1538
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.1552 0.1632
Loa Loa (eye worm) hypothetical protein 0.0022 0.1552 0.1552
Onchocerca volvulus 0.0019 0.101 0.4428
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.2554 0.1718
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.101 0.101
Onchocerca volvulus 0.0022 0.1552 0.6806
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.101 0.233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.1476 0.1136
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.101 0.233
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 1 1
Brugia malayi Doublecortin family protein 0.0022 0.1552 0.1552
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.2554 0.1718
Echinococcus multilocularis cysteine protease 0.0019 0.101 0.0994
Loa Loa (eye worm) hypothetical protein 0.0027 0.2281 0.2281
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.101 0.233
Loa Loa (eye worm) ICD-1 protein 0.0039 0.4334 0.4334
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.1386 0.0419
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.9595 0.955
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.2281 1
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.9595 0.955
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0062 0.8028 0.8028
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.1386 0.3199
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.4927 0.4918
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.101 0.101
Schistosoma mansoni hypothetical protein 0.0022 0.1552 0.1552
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 1 1
Leishmania major basic transcription factor 3a, putative 0.0039 0.4334 0.3698
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.101 0.101
Onchocerca volvulus 0.0019 0.101 0.4428
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.1386 0.0419
Toxoplasma gondii exonuclease III APE 0.0021 0.1386 0.1132
Leishmania major DNA polymerase eta, putative 0.0022 0.1476 0.0519
Onchocerca volvulus 0.0019 0.101 0.4428
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.9595 0.955
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.1386 0.1386
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.2281 0.1414
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.4334 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.1476 0.1136
Echinococcus granulosus tar DNA binding protein 0.0071 0.9514 0.9514
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.1476 0.1136
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0066 0.8585 0.8426
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.1386 0.2958
Schistosoma mansoni DNA polymerase eta 0.0022 0.1476 0.1476
Echinococcus multilocularis cysteine protease 0.0019 0.101 0.0994
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.452 0.452
Loa Loa (eye worm) doublecortin family protein 0.0022 0.1552 0.1552
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.2281 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.1386 0.5
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.1476 0.0519
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.1386 0.1371
Schistosoma mansoni polycystin 1-related 0.0022 0.1552 0.1552
Schistosoma mansoni transcription factor btf3 0.0039 0.4334 0.4334
Loa Loa (eye worm) hypothetical protein 0.0022 0.1476 0.1476
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.1476 0.1461
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.1476 0.1136
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.2554 0.4645
Entamoeba histolytica hypothetical protein 0.0041 0.452 0.452
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.101 0.233
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.2281 1
Onchocerca volvulus 0.0022 0.1552 0.6806
Entamoeba histolytica hypothetical protein 0.0041 0.452 0.452
Entamoeba histolytica cysteine protease, putative 0.0019 0.101 0.101
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.2281 0.2281
Schistosoma mansoni tar DNA-binding protein 0.0071 0.9514 0.9514
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.4334 0.3698
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0071 0.9514 0.9514
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.1476 0.1476
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.1476 0.0519
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.101 0.233
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.1552 0.1552
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.1386 0.1132
Brugia malayi beta-NAC-like protein 0.0039 0.4334 0.4334
Onchocerca volvulus 0.0027 0.2281 1
Loa Loa (eye worm) hypothetical protein 0.002 0.1187 0.1187
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.1187 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Echinococcus multilocularis dna polymerase eta 0.0022 0.1476 0.1461
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Mycobacterium ulcerans hypothetical protein 0.0027 0.2281 1
Brugia malayi RNA binding protein 0.0071 0.9514 0.9514
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.1552 0.1552
Brugia malayi hypothetical protein 0.0028 0.2554 0.2554
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.1386 0.3199
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.1476 0.3665
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.9595 0.9579
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.101 0.0994
Loa Loa (eye worm) hypothetical protein 0.002 0.1187 0.1187
Loa Loa (eye worm) hypothetical protein 0.002 0.1187 0.1187
Loa Loa (eye worm) hypothetical protein 0.002 0.1187 0.1187
Schistosoma mansoni loxhd1 0.0022 0.1552 0.1552

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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