Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.001 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | geminin | 0.0166 | 0.7589 | 0.7589 |
Echinococcus granulosus | carboxylesterase 5A | 0.0207 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.001 | 0.001 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.001 | 0.001 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0166 | 0.7589 | 0.7589 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0207 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.001 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.001 | 0.001 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.7589 | 0.7589 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0207 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.001 | 0.001 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.001 | 0.001 |
Loa Loa (eye worm) | carboxylesterase | 0.0207 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0035 | 0 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0035 | 0 | 0.5 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0207 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.001 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.7589 | 0.7589 |
Brugia malayi | Carboxylesterase family protein | 0.0207 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0207 | 1 | 1 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.001 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0207 | 1 | 1 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0207 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0207 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.