Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | carboxylesterase | 0.016 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0123 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.016 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.016 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0123 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.016 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.016 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.016 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.016 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0123 | 0 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0123 | 0 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.016 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.016 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.016 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0123 | 0 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0123 | 0 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.0123 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.